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Motif ID: TCF4_dimer.p2

Z-value: 2.144

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr15_+_74218962	6.887		LOXL1	lysyl oxidase-like 1
chr9_-_35689799	4.825		TPM2	tropomyosin 2 (beta)
chr9_-_35689902	4.746	NM_003289 NM_213674	TPM2	tropomyosin 2 (beta)
chr2_+_220283098	4.632	NM_001927	DES	desmin
chr4_-_80994183	4.587
chr15_+_74218786	4.435	NM_005576	LOXL1	lysyl oxidase-like 1
chr15_+_74218794	4.372		LOXL1	lysyl oxidase-like 1
chr15_-_48937795	3.928	NM_000138	FBN1	fibrillin 1
chr9_-_75567915	3.771		ALDH1A1	aldehyde dehydrogenase 1 family, member A1
chr2_+_170366211	3.659	NM_006063	KBTBD10	kelch repeat and BTB (POZ) domain containing 10
chr7_+_94023872	3.418	NM_000089	COL1A2	collagen, type I, alpha 2
chr9_-_75568232	3.200	NM_000689	ALDH1A1	aldehyde dehydrogenase 1 family, member A1
chr7_+_94024201	3.143		COL1A2	collagen, type I, alpha 2
chr10_+_124220990	2.978	NM_002775	HTRA1	HtrA serine peptidase 1
chr2_-_175629140	2.835	NM_000079 NM_001039523	CHRNA1	cholinergic receptor, nicotinic, alpha 1 (muscle)
chr3_-_87040246	2.748	NM_016206	VGLL3	vestigial like 3 (Drosophila)
chr11_-_47470687	2.728	NM_005055 NM_032645	RAPSN	receptor-associated protein of the synapse
chr6_-_139695349	2.565	NM_001168389 NM_001168388	CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chrX_-_135863502	2.539	NM_004840	ARHGEF6	Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chrX_-_107018889	2.518		TSC22D3	TSC22 domain family, member 3
chr12_+_81110689	2.434	NM_005593	MYF5	myogenic factor 5
chr17_+_45286713	2.429	NM_002476	MYL4	myosin, light chain 4, alkali; atrial, embryonic
chr3_+_35681008	2.424		ARPP21	cAMP-regulated phosphoprotein, 21kDa
chr7_+_102553343	2.409	NM_001031692 NM_005824	LRRC17	leucine rich repeat containing 17
chr10_-_92681025	2.403	NM_014391	ANKRD1	ankyrin repeat domain 1 (cardiac muscle)
chr10_+_11060069	2.398		CELF2	CUGBP, Elav-like family member 2
chr10_+_31608097	2.392	NM_001174093 NM_001174095 NM_001174096 NM_030751	ZEB1	zinc finger E-box binding homeobox 1
chr2_-_192711923	2.384	NM_004657	SDPR	serum deprivation response
chr8_-_49833823	2.378	NM_003068	SNAI2	snail homolog 2 (Drosophila)
chr11_+_65779461	2.373	NM_001323	CST6	cystatin E/M
chr12_-_91505215	2.360		LUM	lumican
chr21_+_30517897	2.316		C21orf7	chromosome 21 open reading frame 7
chr15_+_74218811	2.302		LOXL1	lysyl oxidase-like 1
chr7_-_131241321	2.294	NM_001018111 NM_005397	PODXL	podocalyxin-like
chr2_-_192711651	2.284		SDPR	serum deprivation response
chr12_-_91505541	2.276	NM_002345	LUM	lumican
chr10_+_11059854	2.246	NM_006561	CELF2	CUGBP, Elav-like family member 2
chr4_-_41216455	2.217	NM_001166050 NM_004307 NM_173075	APBB2	amyloid beta (A4) precursor protein-binding, family B, member 2
chr1_-_201346804	2.215	NM_000364 NM_001001430 NM_001001431 NM_001001432	TNNT2	troponin T type 2 (cardiac)
chr10_+_31607419	2.165		ZEB1	zinc finger E-box binding homeobox 1
chr2_-_37899227	2.153	NM_006449	CDC42EP3	CDC42 effector protein (Rho GTPase binding) 3
chr7_-_45960738	2.141	NM_000598 NM_001013398	IGFBP3	insulin-like growth factor binding protein 3
chr10_-_92680784	2.134		ANKRD1	ankyrin repeat domain 1 (cardiac muscle)
chr1_-_201346783	2.094		TNNT2	troponin T type 2 (cardiac)
chr15_-_35087748	2.049	NM_005159	ACTC1	actin, alpha, cardiac muscle 1
chr7_+_98246595	2.048	NM_002523	NPTX2	neuronal pentraxin II
chr7_+_116140097	2.029	NM_001206748	CAV2	caveolin 2
chrX_-_13956530	2.019		GPM6B	glycoprotein M6B
chr1_-_33168356	2.012	NM_001161708 NM_030786	SYNC	syncoilin, intermediate filament protein
chr2_-_211179765	1.978	NM_079420	MYL1	myosin, light chain 1, alkali; skeletal, fast
chr5_+_148520985	1.958	NM_014945	ABLIM3	actin binding LIM protein family, member 3
chrX_+_70521627	1.950	NM_012278	ITGB1BP2	integrin beta 1 binding protein (melusin) 2
chr4_+_41258941	1.949		UCHL1	ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr10_+_104404195	1.894	NM_030912	TRIM8	tripartite motif containing 8
chr10_+_11060105	1.893		CELF2	CUGBP, Elav-like family member 2
chr10_+_11207053	1.888		CELF2	CUGBP, Elav-like family member 2
chr19_-_45826131	1.859		CKM	creatine kinase, muscle
chr10_-_75410778	1.845	NM_024875	SYNPO2L	synaptopodin 2-like
chr2_-_190044330	1.802	NM_000393	COL5A2	collagen, type V, alpha 2
chr11_-_63933493	1.795	NM_014067	MACROD1	MACRO domain containing 1
chr12_+_78225068	1.795	NM_014903	NAV3	neuron navigator 3
chr3_+_8775485	1.788	NM_001234 NM_033337	CAV3	caveolin 3
chrX_-_107019001	1.765	NM_198057	TSC22D3	TSC22 domain family, member 3
chr6_-_139695739	1.748		CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chr21_+_27011588	1.746	NM_021219	JAM2	junctional adhesion molecule 2
chr17_+_45286427	1.682	NM_001002841	MYL4	myosin, light chain 4, alkali; atrial, embryonic
chr6_-_139695784	1.673	NM_006079	CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chr1_-_95392501	1.668	NM_001839	CNN3	calponin 3, acidic
chr1_+_182992694	1.656
chr1_-_193155723	1.653	NM_003783	B3GALT2	UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr17_-_10452939	1.651	NM_001100112 NM_017534	MYH2	myosin, heavy chain 2, skeletal muscle, adult
chr2_-_179672056	1.626	NM_003319 NM_133378 NM_133379 NM_133432 NM_133437	TTN	titin
chr1_-_144931707	1.614		PDE4DIP	phosphodiesterase 4D interacting protein
chr9_-_97401588	1.611		FBP1	fructose-1,6-bisphosphatase 1
chr8_+_22436641	1.598		PDLIM2	PDZ and LIM domain 2 (mystique)
chr11_-_63933204	1.597		MACROD1	MACRO domain containing 1
chr4_-_57976516	1.594		IGFBP7	insulin-like growth factor binding protein 7
chr8_-_41522724	1.588	NM_001142445 NM_020478 NM_020480	ANK1	ankyrin 1, erythrocytic
chr10_+_11206928	1.572	NM_001025076 NM_001083591	CELF2	CUGBP, Elav-like family member 2
chr21_-_39288661	1.569	NM_002240	KCNJ6	potassium inwardly-rectifying channel, subfamily J, member 6
chr4_-_57976550	1.561	NM_001253835 NM_001553	IGFBP7	insulin-like growth factor binding protein 7
chr4_-_157892545	1.557	NM_016205	PDGFC	platelet derived growth factor C
chr21_-_44845920	1.544		SIK1	salt-inducible kinase 1
chr15_+_63340314	1.544	NM_001018008	TPM1	tropomyosin 1 (alpha)
chr4_-_57976355	1.519		IGFBP7	insulin-like growth factor binding protein 7
chr1_+_223889253	1.518	NM_001146068	CAPN2	calpain 2, (m/II) large subunit
chr2_+_71295685	1.509		NAGK	N-acetylglucosamine kinase
chrX_-_13956644	1.468	NM_001001994	GPM6B	glycoprotein M6B
chr11_+_1886394	1.457	NM_001242932	LSP1	lymphocyte-specific protein 1
chr19_-_46974663	1.441		PNMAL1	PNMA-like 1
chr6_-_137113166	1.439
chr3_-_178789535	1.427		ZMAT3	zinc finger, matrin-type 3
chr2_-_152590983	1.412	NM_001164507 NM_001164508 NM_004543	NEB	nebulin
chr1_-_85930610	1.411		DDAH1	dimethylarginine dimethylaminohydrolase 1
chr11_-_119294242	1.408	NM_006288	THY1	Thy-1 cell surface antigen
chr22_-_19511777	1.404		CLDN5	claudin 5
chr3_-_178789597	1.381	NM_022470 NM_152240	ZMAT3	zinc finger, matrin-type 3
chrX_-_135863033	1.368		ARHGEF6	Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr5_-_88199868	1.367	NM_001131005 NM_001193347	MEF2C	myocyte enhancer factor 2C
chr11_+_86511490	1.362	NM_007173	PRSS23	protease, serine, 23
chr15_-_26108236	1.359	NM_024490	ATP10A	ATPase, class V, type 10A
chrX_-_135863104	1.359		ARHGEF6	Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr7_+_116166346	1.337	NM_001172896 NM_001172897	CAV1	caveolin 1, caveolae protein, 22kDa
chr11_-_119293848	1.304		THY1	Thy-1 cell surface antigen
chr11_+_1860232	1.290	NM_003282	TNNI2	troponin I type 2 (skeletal, fast)
chr5_-_172755195	1.284		STC2	stanniocalcin 2
chr2_+_223916861	1.280	NM_080671	KCNE4	potassium voltage-gated channel, Isk-related family, member 4
chr1_-_203144910	1.268	NM_004997	MYBPH	myosin binding protein H
chr19_-_12886263	1.228		HOOK2	hook homolog 2 (Drosophila)
chr3_+_158787040	1.222	NM_001197113 NM_001197114 NM_001042705 NM_001042706 NM_001197100	IQCJ-SCHIP1 IQCJ	IQCJ-SCHIP1 readthrough IQ motif containing J
chr6_+_129204285	1.222	NM_000426 NM_001079823	LAMA2	laminin, alpha 2
chr7_+_44788453	1.211	NM_031449	ZMIZ2	zinc finger, MIZ-type containing 2
chr8_+_1922030	1.192	NM_014867	KBTBD11	kelch repeat and BTB (POZ) domain containing 11
chr4_-_157892054	1.187		PDGFC	platelet derived growth factor C
chr5_+_140864626	1.177	NM_018928 NM_032406	PCDHGC4	protocadherin gamma subfamily C, 4
chr7_-_37956377	1.164		SFRP4	secreted frizzled-related protein 4
chr5_-_151066492	1.159	NM_003118	SPARC	secreted protein, acidic, cysteine-rich (osteonectin)
chr3_-_99833348	1.153	NM_001042459 NM_182909	FILIP1L	filamin A interacting protein 1-like
chr3_-_15900928	1.138	NM_015199	ANKRD28	ankyrin repeat domain 28
chr16_-_31076408	1.132	NM_001172669 NM_001172670	ZNF668	zinc finger protein 668
chr5_-_176899870	1.131	NM_080881	DBN1	drebrin 1
chr16_+_7382750	1.129	NM_145891 NM_145892 NM_145893	RBFOX1	RNA binding protein, fox-1 homolog (C. elegans) 1
chr19_-_49658645	1.120	NM_002152	HRC	histidine rich calcium binding protein
chr1_+_145524989	1.119	NM_003637	ITGA10	integrin, alpha 10
chr19_-_18717577	1.116		CRLF1	cytokine receptor-like factor 1
chr14_-_23821423	1.103	NM_020372	SLC22A17	solute carrier family 22, member 17
chr6_+_57037058	1.083	NM_004282	BAG2	BCL2-associated athanogene 2
chr6_+_46097700	1.081	NM_014936	ENPP4	ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)
chr11_-_6341708	1.081	NM_145040	PRKCDBP	protein kinase C, delta binding protein
chrX_+_135251454	1.076	NM_001159704	FHL1	four and a half LIM domains 1
chr1_-_40367539	1.075	NM_001033081 NM_001033082 NM_005376	MYCL1	v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian)
chr6_-_46459010	1.075	NM_001251974	RCAN2	regulator of calcineurin 2
chr6_-_137113624	1.070	NM_005923	MAP3K5	mitogen-activated protein kinase kinase kinase 5
chr11_+_69455837	1.067	NM_053056	CCND1	cyclin D1
chr1_-_23885916	1.066		ID3	inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr1_-_147931877	1.048		FLJ39739	uncharacterized FLJ39739
chr15_-_42749710	1.042	NM_022473	ZFP106	zinc finger protein 106 homolog (mouse)
chr19_-_18717631	1.033	NM_004750	CRLF1	cytokine receptor-like factor 1
chr12_+_122150638	1.025	NM_001080825	TMEM120B	transmembrane protein 120B
chr1_-_17445865	1.007	NM_007365	PADI2	peptidyl arginine deiminase, type II
chr21_+_47531369	1.006		COL6A2	collagen, type VI, alpha 2
chr11_-_64014381	1.001		PPP1R14B	protein phosphatase 1, regulatory (inhibitor) subunit 14B
chrX_-_6146655	1.001	NM_181332	NLGN4X	neuroligin 4, X-linked
chr6_+_46097818	0.993		ENPP4	ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)
chr19_-_11308184	0.972	NM_001136191	KANK2	KN motif and ankyrin repeat domains 2
chr6_-_137113602	0.959		MAP3K5	mitogen-activated protein kinase kinase kinase 5
chr6_-_137113721	0.954		MAP3K5	mitogen-activated protein kinase kinase kinase 5
chr9_+_133320093	0.953	NM_000050 NM_054012	ASS1	argininosuccinate synthase 1
chr10_+_17271341	0.949		VIM	vimentin
chr1_+_86046434	0.948	NM_001554	CYR61	cysteine-rich, angiogenic inducer, 61
chr9_+_34990715	0.939		DNAJB5	DnaJ (Hsp40) homolog, subfamily B, member 5
chr4_-_186733372	0.934	NM_003603 NM_001145670	SORBS2	sorbin and SH3 domain containing 2
chr11_+_1860718	0.928	NM_001145829	TNNI2	troponin I type 2 (skeletal, fast)
chr11_+_44587140	0.927	NM_001024844 NM_002231	CD82	CD82 molecule
chr5_+_95066628	0.926	NM_014899	RHOBTB3	Rho-related BTB domain containing 3
chr1_-_109584589	0.923	NM_001142550 NM_001142551 NM_014969	WDR47	WD repeat domain 47
chr19_-_12886421	0.919	NM_001100176 NM_013312	HOOK2	hook homolog 2 (Drosophila)
chr17_+_16945766	0.909	NM_015134 NM_201274	MPRIP	myosin phosphatase Rho interacting protein
chr15_-_23932364	0.908
chr2_-_1748317	0.907		PXDN	peroxidasin homolog (Drosophila)
chr5_+_71403040	0.907	NM_005909	MAP1B	microtubule-associated protein 1B
chr15_-_56209305	0.907	NM_198400	NEDD4	neural precursor cell expressed, developmentally down-regulated 4
chr6_-_137113529	0.906		MAP3K5	mitogen-activated protein kinase kinase kinase 5
chr8_+_22436253	0.894	NM_021630	PDLIM2	PDZ and LIM domain 2 (mystique)
chr11_+_67776016	0.885	NM_001161473	ALDH3B1	aldehyde dehydrogenase 3 family, member B1
chrX_-_13956445	0.884
chr12_-_110434028	0.879		GIT2	G protein-coupled receptor kinase interacting ArfGAP 2
chr2_-_230135954	0.878	NM_001100818 NM_017933	PID1	phosphotyrosine interaction domain containing 1
chr19_-_18717467	0.877		CRLF1	cytokine receptor-like factor 1
chr10_+_17271956	0.868		VIM	vimentin
chr2_-_1748240	0.868		PXDN	peroxidasin homolog (Drosophila)
chr17_-_48264039	0.866		COL1A1	collagen, type I, alpha 1
chr6_-_46293404	0.865		RCAN2	regulator of calcineurin 2
chr19_-_45826232	0.864	NM_001824	CKM	creatine kinase, muscle
chr10_+_17271859	0.860		VIM	vimentin
chr14_-_34419957	0.859	NM_022073	EGLN3	egl nine homolog 3 (C. elegans)
chr11_+_44587212	0.854		CD82	CD82 molecule
chr9_-_97401746	0.851		FBP1	fructose-1,6-bisphosphatase 1
chr9_+_34990266	0.850	NM_001135005	DNAJB5	DnaJ (Hsp40) homolog, subfamily B, member 5
chr2_+_238395863	0.845	NM_001042467 NM_024101	MLPH	melanophilin
chr6_-_24911194	0.844	NM_014722	FAM65B	family with sequence similarity 65, member B
chr17_+_7348362	0.842	NM_000747	CHRNB1	cholinergic receptor, nicotinic, beta 1 (muscle)
chr12_+_6833425	0.842	NM_001164093	COPS7A	COP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis)
chr8_-_17941598	0.839		ASAH1	N-acylsphingosine amidohydrolase (acid ceramidase) 1
chr11_-_35547144	0.836	NM_001001991 NM_015430	PAMR1	peptidase domain containing associated with muscle regeneration 1
chr15_+_83776323	0.831	NM_001144903 NM_023003	TM6SF1	transmembrane 6 superfamily member 1
chr17_+_1665233	0.826	NM_002615	SERPINF1	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr10_-_62703822	0.824	NM_001242359 NM_014836	RHOBTB1	Rho-related BTB domain containing 1
chr16_+_89238160	0.820	NM_004933	CDH15	cadherin 15, type 1, M-cadherin (myotubule)
chr17_+_1665281	0.812		SERPINF1	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr11_-_61658853	0.806	NM_021727	FADS3	fatty acid desaturase 3
chr8_+_37654833	0.806		GPR124	G protein-coupled receptor 124
chr17_+_68165660	0.804	NM_000891	KCNJ2	potassium inwardly-rectifying channel, subfamily J, member 2
chr1_+_203097427	0.802		ADORA1	adenosine A1 receptor
chr1_+_89990396	0.797	NM_001134476	LRRC8B	leucine rich repeat containing 8 family, member B
chr12_-_111358353	0.792	NM_000432	MYL2	myosin, light chain 2, regulatory, cardiac, slow
chr9_-_89562103	0.788	NM_002048	GAS1	growth arrest-specific 1
chr19_-_46285645	0.788		DMPK	dystrophia myotonica-protein kinase
chr17_+_7348840	0.787		CHRNB1	cholinergic receptor, nicotinic, beta 1 (muscle)
chr10_+_99258615	0.787	NM_024954	UBTD1	ubiquitin domain containing 1

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
35.15	4.44e-12	GO:0030049	muscle filament sliding
35.15	4.44e-12	GO:0033275	actin-myosin filament sliding
34.23	6.21e-12	GO:0070252	actin-mediated cell contraction
25.50	2.24e-10	GO:0030048	actin filament-based movement
11.61	2.85e-10	GO:0007517	muscle organ development
11.52	1.82e-09	GO:0006936	muscle contraction
8.71	5.50e-09	GO:0061061	muscle structure development
10.56	6.49e-09	GO:0003012	muscle system process
26.28	3.35e-07	GO:0006941	striated muscle contraction
10.20	3.16e-05	GO:0042692	muscle cell differentiation
6.33	8.55e-05	GO:0030029	actin filament-based process
16.56	1.26e-04	GO:0055001	muscle cell development
23.65	1.23e-03	GO:0031032	actomyosin structure organization
15.77	1.33e-03	GO:0055002	striated muscle cell development
11.66	1.46e-03	GO:0051146	striated muscle cell differentiation
8.93	2.05e-03	GO:0014706	striated muscle tissue development
8.16	4.03e-03	GO:0060537	muscle tissue development
31.53	4.15e-03	GO:0043462	regulation of ATPase activity
31.53	4.15e-03	GO:0060048	cardiac muscle contraction
1.68	4.92e-03	GO:0032501	multicellular organismal process
2.61	6.73e-03	GO:0003008	system process
59.11	7.82e-03	GO:0031579	membrane raft organization
1.92	8.51e-03	GO:0048856	anatomical structure development
24.89	1.15e-02	GO:0003015	heart process
24.89	1.15e-02	GO:0030239	myofibril assembly
24.89	1.15e-02	GO:0060047	heart contraction
1.84	1.80e-02	GO:0007275	multicellular organismal development
4.59	1.84e-02	GO:0044057	regulation of system process
2.23	2.04e-02	GO:0048513	organ development
3.01	2.86e-02	GO:0009888	tissue development
1.91	3.06e-02	GO:0048731	system development
39.41	3.22e-02	GO:0045214	sarcomere organization
9.10	3.36e-02	GO:0008016	regulation of heart contraction
35.47	4.58e-02	GO:0032781	positive regulation of ATPase activity
118.21	4.80e-02	GO:0001765	membrane raft assembly
118.21	4.80e-02	GO:0070836	caveola assembly

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
19.33	1.52e-15	GO:0030016	myofibril
22.00	1.67e-15	GO:0030017	sarcomere
18.11	4.81e-15	GO:0043292	contractile fiber
18.73	2.49e-14	GO:0044449	contractile fiber part
7.77	6.75e-09	GO:0015629	actin cytoskeleton
23.07	2.03e-07	GO:0031674	I band
45.47	6.43e-06	GO:0005865	striated muscle thin filament
22.17	3.22e-05	GO:0030018	Z disc
2.60	9.22e-04	GO:0005856	cytoskeleton
2.78	9.61e-03	GO:0044430	cytoskeletal part
10.95	1.20e-02	GO:0016459	myosin complex
32.25	1.24e-02	GO:0005583	fibrillar collagen
7.25	2.38e-02	GO:0044420	extracellular matrix part
4.00	2.67e-02	GO:0031012	extracellular matrix
1.82	4.90e-02	GO:0043228	non-membrane-bounded organelle
1.82	4.90e-02	GO:0043232	intracellular non-membrane-bounded organelle

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
4.92	1.55e-07	GO:0005198	structural molecule activity
23.07	2.07e-07	GO:0008307	structural constituent of muscle
4.81	3.89e-06	GO:0008092	cytoskeletal protein binding
5.68	6.10e-05	GO:0003779	actin binding
8.70	3.68e-02	GO:0005201	extracellular matrix structural constituent