Motif ID: TEAD1.p2

Z-value: 3.683


Transcription factors associated with TEAD1.p2:

Gene SymbolEntrez IDGene Name
TEAD1 7003 TEA domain family member 1 (SV40 transcriptional enhancer factor)
TEAD2 8463 TEA domain family member 2
TEAD3 7005 TEAD3 TEA domain family member 3
TEAD4 7004 TEAD4 TEA domain family member 4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
TEAD1chr11_+_126958510.926.5e-07Click!
TEAD3chr6_-_354647160.582.0e-02Click!
TEAD4chr12_+_30689890.448.9e-02Click!


Activity profile for motif TEAD1.p2.

activity profile for motif TEAD1.p2


Sorted Z-values histogram for motif TEAD1.p2

Sorted Z-values for motif TEAD1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TEAD1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_-_39424930 24.249 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr6_-_132272311 22.068 NM_001901
 CTGF
connective tissue growth factor
chr5_-_39425030 13.179 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr15_+_39873276 11.967 NM_003246
 THBS1
thrombospondin 1
chr6_-_128841432 10.814 NM_002844
NM_001135648
 PTPRK

protein tyrosine phosphatase, receptor type, K

chr15_+_63334753 10.661 NM_000366
NM_001018004
NM_001018005
NM_001018006
NM_001018007
NM_001018020
 TPM1





tropomyosin 1 (alpha)





chr15_+_63335086 10.289 TPM1
tropomyosin 1 (alpha)
chr11_-_6341708 10.213 NM_145040
 PRKCDBP
protein kinase C, delta binding protein
chr5_-_39425297 9.914 NM_001244871
NM_001343
 DAB2

disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)

chr10_-_90712510 9.651 NM_001613
 ACTA2
actin, alpha 2, smooth muscle, aorta
chr11_+_114166534 9.389 NM_006169
 NNMT
nicotinamide N-methyltransferase
chr2_-_190044330 9.150 NM_000393
 COL5A2
collagen, type V, alpha 2
chr7_+_134464161 8.451 NM_004342
NM_033138
NM_033157
 CALD1


caldesmon 1


chr10_-_125853102 8.074 CHST15
carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
chr20_+_35169876 8.068 NM_006097
NM_181526
 MYL9

myosin, light chain 9, regulatory

chr5_-_151066492 7.960 NM_003118
 SPARC
secreted protein, acidic, cysteine-rich (osteonectin)
chr20_+_35169897 7.703 MYL9
myosin, light chain 9, regulatory
chr7_+_134464417 7.350 CALD1
caldesmon 1
chr12_-_13153200 7.254 NM_015987
 HEBP1
heme binding protein 1
chr3_-_149086884 7.190 TM4SF1
transmembrane 4 L six family member 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 42 entries
Enrichment   P-value GO Accession GO Term
18.20 7.03e-04 GO:0007044 cell-substrate junction assembly
8.50 1.68e-02 GO:0090257 regulation of muscle system process
7.93 2.66e-02 GO:0007160 cell-matrix adhesion
7.90 7.18e-03 GO:0030198 extracellular matrix organization
7.42 2.55e-04 GO:0034330 cell junction organization
7.21 4.08e-03 GO:0014706 striated muscle tissue development
6.65 7.99e-03 GO:0034329 cell junction assembly
6.59 8.57e-03 GO:0060537 muscle tissue development
6.44 3.33e-03 GO:0043062 extracellular structure organization
5.52 1.31e-02 GO:0006936 muscle contraction
5.34 2.49e-03 GO:0048514 blood vessel morphogenesis
5.13 5.74e-04 GO:0001568 blood vessel development
5.12 2.27e-04 GO:0001944 vasculature development
5.06 2.80e-02 GO:0003012 muscle system process
4.83 2.91e-03 GO:0030334 regulation of cell migration
4.78 3.21e-03 GO:2000145 regulation of cell motility
4.46 6.97e-03 GO:0040012 regulation of locomotion
4.39 8.28e-03 GO:0051270 regulation of cellular component movement
4.29 3.77e-05 GO:0072358 cardiovascular system development
4.29 3.77e-05 GO:0072359 circulatory system development

Gene overrepresentation in compartment category:

Showing 1 to 20 of 28 entries
Enrichment   P-value GO Accession GO Term
84.89 2.13e-02 GO:0005610 laminin-5 complex
42.45 4.82e-03 GO:0001527 microfibril
25.47 2.79e-02 GO:0043205 fibril
12.13 4.70e-02 GO:0008305 integrin complex
11.72 5.55e-05 GO:0005604 basement membrane
11.32 8.84e-08 GO:0005925 focal adhesion
10.84 1.48e-07 GO:0005924 cell-substrate adherens junction
10.40 2.42e-07 GO:0030055 cell-substrate junction
10.40 2.42e-07 GO:0044420 extracellular matrix part
9.44 6.06e-03 GO:0016459 myosin complex
9.01 6.92e-08 GO:0005912 adherens junction
8.09 2.90e-07 GO:0070161 anchoring junction
6.12 7.55e-03 GO:0043292 contractile fiber
5.89 2.89e-02 GO:0044449 contractile fiber part
5.80 2.04e-05 GO:0016323 basolateral plasma membrane
5.72 3.46e-02 GO:0030016 myofibril
5.55 4.63e-06 GO:0005578 proteinaceous extracellular matrix
5.46 2.83e-07 GO:0031012 extracellular matrix
5.35 1.96e-02 GO:0043235 receptor complex
4.81 1.69e-02 GO:0031252 cell leading edge

Gene overrepresentation in function category:

Showing 1 to 10 of 10 entries
Enrichment   P-value GO Accession GO Term
84.89 2.14e-02 GO:0004923 leukemia inhibitory factor receptor activity
14.50 6.85e-05 GO:0008307 structural constituent of muscle
11.24 1.46e-05 GO:0005201 extracellular matrix structural constituent
8.41 4.56e-05 GO:0019838 growth factor binding
5.54 5.64e-03 GO:0001871 pattern binding
5.54 5.64e-03 GO:0030247 polysaccharide binding
5.31 2.08e-02 GO:0005539 glycosaminoglycan binding
3.70 1.74e-05 GO:0005198 structural molecule activity
2.70 7.66e-03 GO:0042802 identical protein binding
1.33 2.01e-02 GO:0005515 protein binding