Motif ID: TFAP2B.p2

Z-value: 1.554


Transcription factors associated with TFAP2B.p2:

Gene SymbolEntrez IDGene Name
TFAP2B 7021 transcription factor AP-2 beta (activating enhancer binding protein 2 beta)

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
TFAP2Bchr6_+_50786438-0.332.1e-01Click!


Activity profile for motif TFAP2B.p2.

activity profile for motif TFAP2B.p2


Sorted Z-values histogram for motif TFAP2B.p2

Sorted Z-values for motif TFAP2B.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TFAP2B.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_129325175 2.396 NM_015103
PLXND1
plexin D1
chr21_+_46825001 2.344 NM_130445
COL18A1
collagen, type XVIII, alpha 1
chr17_-_76921205 2.140 TIMP2
TIMP metallopeptidase inhibitor 2
chr19_-_18717467 2.105 CRLF1
cytokine receptor-like factor 1
chr7_-_50861114 2.077 NM_001001555
GRB10
growth factor receptor-bound protein 10
chr17_-_76921076 1.969 TIMP2
TIMP metallopeptidase inhibitor 2
chr15_+_63334753 1.954 NM_000366
NM_001018004
NM_001018005
NM_001018006
NM_001018007
NM_001018020
TPM1





tropomyosin 1 (alpha)





chr19_-_18717631 1.883 NM_004750
CRLF1
cytokine receptor-like factor 1
chr20_-_50384861 1.851 ATP9A
ATPase, class II, type 9A
chr18_-_25757351 1.803 NM_001792
CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr1_-_85930610 1.796 DDAH1
dimethylarginine dimethylaminohydrolase 1
chr8_+_136469557 1.731 NM_006558
KHDRBS3
KH domain containing, RNA binding, signal transduction associated 3
chr15_+_63335086 1.659 TPM1
tropomyosin 1 (alpha)
chr2_+_9346909 1.618 ASAP2
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
chr7_-_50860665 1.573 GRB10
growth factor receptor-bound protein 10
chr20_-_50384899 1.555 NM_006045
ATP9A
ATPase, class II, type 9A
chr14_+_105941061 1.543 NM_001312
CRIP2
cysteine-rich protein 2
chr17_-_76921453 1.526 NM_003255
TIMP2
TIMP metallopeptidase inhibitor 2
chr3_-_185542807 1.501 NM_001007225
NM_006548
IGF2BP2

insulin-like growth factor 2 mRNA binding protein 2

chr19_-_18717577 1.491 CRLF1
cytokine receptor-like factor 1
chr2_-_161349874 1.443 RBMS1
RNA binding motif, single stranded interacting protein 1
chr21_+_46825291 1.431


chr8_+_136470108 1.418 KHDRBS3
KH domain containing, RNA binding, signal transduction associated 3
chr14_-_30396811 1.368 NM_002742
PRKD1
protein kinase D1
chr10_-_15413054 1.340 NM_001010924
FAM171A1
family with sequence similarity 171, member A1
chr2_+_9346876 1.331 NM_001135191
NM_003887
ASAP2

ArfGAP with SH3 domain, ankyrin repeat and PH domain 2

chr1_-_85930733 1.308 NM_012137
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr2_+_236402685 1.258 NM_001037131
NM_001244888
NM_014914
AGAP1


ArfGAP with GTPase domain, ankyrin repeat and PH domain 1


chr7_+_128470462 1.250 NM_001127487
NM_001458
FLNC

filamin C, gamma

chr3_-_38691118 1.246 NM_000335
NM_001099404
NM_001099405
NM_198056
NM_001160160
NM_001160161
SCN5A





sodium channel, voltage-gated, type V, alpha subunit





chr5_-_176900653 1.195 NM_004395
DBN1
drebrin 1
chr1_-_22263676 1.189 NM_005529
HSPG2
heparan sulfate proteoglycan 2
chr11_-_86666211 1.187 NM_012193
FZD4
frizzled family receptor 4
chr11_-_65640199 1.178 NM_016938
EFEMP2
EGF containing fibulin-like extracellular matrix protein 2
chr6_-_52441815 1.171 NM_012288
TRAM2
translocation associated membrane protein 2
chr9_+_103235634 1.146 TMEFF1
transmembrane protein with EGF-like and two follistatin-like domains 1
chr5_+_34656482 1.145 RAI14
retinoic acid induced 14
chr11_-_78128765 1.138 GAB2
GRB2-associated binding protein 2
chr7_-_131241321 1.126 NM_001018111
NM_005397
PODXL

podocalyxin-like

chr5_+_34656595 1.120 NM_001145520
RAI14
retinoic acid induced 14
chr5_+_34656367 1.105 NM_001145522
NM_015577
RAI14

retinoic acid induced 14

chr19_-_1567875 1.097 NM_001174118
NM_203304
MEX3D

mex-3 homolog D (C. elegans)

chr5_-_176900591 1.086 DBN1
drebrin 1
chr1_-_95392501 1.075 NM_001839
CNN3
calponin 3, acidic
chr2_+_102314162 1.073 NM_001242560
NM_004834
NM_145686
NM_001242559
NM_145687
MAP4K4




mitogen-activated protein kinase kinase kinase kinase 4




chr14_+_105781180 1.070 PACS2
phosphofurin acidic cluster sorting protein 2
chr12_+_3068442 1.053 NM_003213
NM_201441
NM_201443
TEAD4


TEA domain family member 4


chr19_+_33685489 1.048 NM_002333
LRP3
low density lipoprotein receptor-related protein 3
chr11_+_46402333 1.047 NM_001012334
MDK
midkine (neurite growth-promoting factor 2)
chr11_-_2160199 1.037 NM_000612
IGF2
insulin-like growth factor 2 (somatomedin A)
chr3_-_185542744 1.035 IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr5_-_126366068 1.033 MARCH3
membrane-associated ring finger (C3HC4) 3
chr7_-_150946031 1.027 SMARCD3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr6_-_52441714 1.026 TRAM2
translocation associated membrane protein 2
chr9_+_103235489 1.020 NM_003692
TMEFF1
transmembrane protein with EGF-like and two follistatin-like domains 1
chr2_+_177053306 1.013 NM_024501
HOXD1
homeobox D1
chr3_-_52567708 1.009 NM_001134231
NT5DC2
5'-nucleotidase domain containing 2
chr18_-_5543967 1.005 NM_012307
EPB41L3
erythrocyte membrane protein band 4.1-like 3
chr10_+_104404195 1.005 NM_030912
TRIM8
tripartite motif containing 8
chr11_-_75236866 0.999 GDPD5
glycerophosphodiester phosphodiesterase domain containing 5
chr2_-_99347430 0.987 MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr9_+_138371627 0.984 NM_014811
PPP1R26
protein phosphatase 1, regulatory subunit 26
chr6_-_170124065 0.982 PHF10
PHD finger protein 10
chr2_+_97481977 0.980 NM_017623
NM_199078
CNNM3

cyclin M3

chr1_-_95392449 0.978 CNN3
calponin 3, acidic
chr3_-_149688638 0.976 NM_002628
NM_053024
PFN2

profilin 2

chr1_+_25071967 0.972 CLIC4
chloride intracellular channel 4
chr22_+_38201113 0.964 NM_005318
H1F0
H1 histone family, member 0
chr2_-_39664430 0.956 MAP4K3
mitogen-activated protein kinase kinase kinase kinase 3
chr5_-_179498598 0.949 RNF130
ring finger protein 130
chr13_+_98795410 0.932 NM_001001715
NM_005766
FARP1

FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)

chr6_+_148663953 0.930 SASH1
SAM and SH3 domain containing 1
chr9_+_96338671 0.906 NM_005392
PHF2
PHD finger protein 2
chr21_-_44846927 0.900 NM_173354
SIK1
salt-inducible kinase 1
chr14_+_100259445 0.898 NM_001008707
NM_004434
EML1

echinoderm microtubule associated protein like 1

chr3_-_124605840 0.897 ITGB5
integrin, beta 5
chr2_-_16847070 0.892 NM_030797
FAM49A
family with sequence similarity 49, member A
chr10_-_735522 0.890 NM_014974
DIP2C
DIP2 disco-interacting protein 2 homolog C (Drosophila)
chr2_-_39664291 0.877 MAP4K3
mitogen-activated protein kinase kinase kinase kinase 3
chr9_+_137533643 0.875 NM_000093
COL5A1
collagen, type V, alpha 1
chr13_+_98795468 0.873 FARP1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chrX_+_117861523 0.871 NM_001560
IL13RA1
interleukin 13 receptor, alpha 1
chr11_-_2906960 0.863 NM_000076
NM_001122630
NM_001122631
CDKN1C


cyclin-dependent kinase inhibitor 1C (p57, Kip2)


chr13_+_98795710 0.852 FARP1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr22_+_23412364 0.851 NM_002073
GNAZ
guanine nucleotide binding protein (G protein), alpha z polypeptide
chr6_-_170124086 0.851 NM_018288
NM_133325
PHF10

PHD finger protein 10

chr1_+_39547088 0.845 NM_012090
MACF1
microtubule-actin crosslinking factor 1
chr2_-_127864505 0.844 NM_004305
NM_139343
NM_139344
NM_139345
NM_139346
NM_139347
NM_139348
NM_139349
NM_139350
NM_139351
BIN1









bridging integrator 1









chr1_+_25071906 0.842 CLIC4
chloride intracellular channel 4
chr11_-_63536112 0.837 NM_001144936
C11orf95
chromosome 11 open reading frame 95
chr8_+_97657581 0.833 PGCP
plasma glutamate carboxypeptidase
chr22_-_29075708 0.833 NM_001145418
TTC28
tetratricopeptide repeat domain 28
chr6_+_71998508 0.833 OGFRL1
opioid growth factor receptor-like 1
chr19_+_3094528 0.829 GNA11
guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
chr1_+_2160133 0.827 NM_003036
SKI
v-ski sarcoma viral oncogene homolog (avian)
chr6_+_71998476 0.821 NM_024576
OGFRL1
opioid growth factor receptor-like 1
chr19_+_3094266 0.818 NM_002067
GNA11
guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
chr2_-_220436010 0.813 OBSL1
obscurin-like 1
chr8_+_97657592 0.799 PGCP
plasma glutamate carboxypeptidase
chr8_+_1711869 0.797 NM_018941
CLN8
ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
chr6_+_163835783 0.781 QKI
QKI, KH domain containing, RNA binding
chr5_-_111093251 0.770 NM_001142479
NM_001142480
NM_001142478
C5orf13


chromosome 5 open reading frame 13


chr14_+_59104736 0.768 NM_001079520
NM_016651
DACT1

dapper, antagonist of beta-catenin, homolog 1 (Xenopus laevis)

chr3_-_52567809 0.762 NT5DC2
5'-nucleotidase domain containing 2
chr4_+_41362750 0.760 NM_001112717
NM_001112718
NM_014988
LIMCH1


LIM and calponin homology domains 1


chr8_+_97506141 0.759 SDC2
syndecan 2
chr14_+_105780903 0.757 PACS2
phosphofurin acidic cluster sorting protein 2
chr7_+_94139331 0.756 CASD1
CAS1 domain containing 1
chr8_-_12990731 0.753 NM_006094
DLC1
deleted in liver cancer 1
chr20_-_60942300 0.752 NM_005560
LAMA5
laminin, alpha 5
chr8_+_97506071 0.747 SDC2
syndecan 2
chr3_+_187871473 0.738 NM_001167672
LPP
LIM domain containing preferred translocation partner in lipoma
chr6_+_148663728 0.734 NM_015278
SASH1
SAM and SH3 domain containing 1
chr8_-_67525426 0.732 NM_001080416
NM_001144755
MYBL1

LOC645895
v-myb myeloblastosis viral oncogene homolog (avian)-like 1

uncharacterized LOC645895
chr10_-_62703822 0.728 NM_001242359
NM_014836
RHOBTB1

Rho-related BTB domain containing 1

chr4_+_4861371 0.727 NM_002448
MSX1
msh homeobox 1
chr10_+_123922940 0.726 TACC2
transforming, acidic coiled-coil containing protein 2
chr10_-_15210610 0.724 NM_004808
NMT2
N-myristoyltransferase 2
chr2_+_85811530 0.721 NM_006634
VAMP5
vesicle-associated membrane protein 5 (myobrevin)
chr4_-_186456580 0.715 NM_001114107
NM_014476
PDLIM3

PDZ and LIM domain 3

chr7_-_150945731 0.715 NM_001003801
SMARCD3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr6_-_7910716 0.715 NM_030810
TXNDC5
thioredoxin domain containing 5 (endoplasmic reticulum)
chr3_-_124606129 0.709 NM_002213
ITGB5
integrin, beta 5
chr12_-_124457099 0.709 NM_025140
CCDC92
coiled-coil domain containing 92
chr7_+_98246595 0.704 NM_002523
NPTX2
neuronal pentraxin II
chr10_-_17659365 0.692 NM_014241
PTPLA
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A
chr1_+_25071759 0.691 NM_013943
CLIC4
chloride intracellular channel 4
chr13_+_48807492 0.688 ITM2B
integral membrane protein 2B
chrX_-_34675366 0.683 NM_031442
TMEM47
transmembrane protein 47
chr8_+_97506020 0.681 SDC2
syndecan 2
chr4_-_80994183 0.680


chr2_-_218843541 0.679 TNS1
tensin 1
chr17_-_56032494 0.677 CUEDC1
CUE domain containing 1
chr2_-_175869910 0.675 NM_001822
NM_001025201
CHN1

chimerin (chimaerin) 1

chr4_+_3768295 0.674 NM_000683
ADRA2C
adrenergic, alpha-2C-, receptor
chr8_+_97657452 0.673 NM_016134
PGCP
plasma glutamate carboxypeptidase
chr11_+_832965 0.672 CD151
CD151 molecule (Raph blood group)
chr7_-_19157262 0.672 NM_000474
TWIST1
twist homolog 1 (Drosophila)
chr17_-_78194085 0.672 NM_000199
SGSH
N-sulfoglucosamine sulfohydrolase
chr12_-_106641675 0.668 NM_006825
CKAP4
cytoskeleton-associated protein 4
chr8_+_97506478 0.666 SDC2
syndecan 2
chr7_-_559479 0.662 NM_002607
NM_033023
PDGFA

platelet-derived growth factor alpha polypeptide

chr3_+_39851028 0.661 NM_015460
MYRIP
myosin VIIA and Rab interacting protein
chr12_-_15942350 0.657 NM_004447
EPS8
epidermal growth factor receptor pathway substrate 8
chr12_-_15942116 0.655 EPS8
epidermal growth factor receptor pathway substrate 8
chr5_+_72921980 0.655 NM_001080479
NM_001177693
RGNEF

190 kDa guanine nucleotide exchange factor

chr6_+_71998514 0.654 OGFRL1
opioid growth factor receptor-like 1
chr11_-_75236418 0.651 NM_030792
GDPD5
glycerophosphodiester phosphodiesterase domain containing 5
chr19_+_50016500 0.646 FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr14_-_105262078 0.644 NM_001014431
NM_001014432
AKT1

v-akt murine thymoma viral oncogene homolog 1

chr11_+_833007 0.640 CD151
CD151 molecule (Raph blood group)
chr5_-_111093792 0.638 NM_001142477
NM_001142476
C5orf13

chromosome 5 open reading frame 13

chr16_-_4166185 0.632 NM_001116
ADCY9
adenylate cyclase 9
chr22_+_38201232 0.632 H1F0
H1 histone family, member 0
chr16_+_58497993 0.631 NM_001130487
NDRG4
NDRG family member 4
chr1_-_94702916 0.629 ARHGAP29
Rho GTPase activating protein 29
chr14_-_105262015 0.629 AKT1
v-akt murine thymoma viral oncogene homolog 1
chr3_+_61547179 0.629 NM_002841
PTPRG
protein tyrosine phosphatase, receptor type, G
chr2_-_1748240 0.629 PXDN
peroxidasin homolog (Drosophila)
chr8_+_61591239 0.628 NM_017780
CHD7
chromodomain helicase DNA binding protein 7
chr3_+_37903643 0.627 NM_001008392
NM_005808
CTDSPL

CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like

chr2_-_113191106 0.623 NM_001164463
NM_005054
RGPD8
RGPD5
RANBP2-like and GRIP domain containing 8
RANBP2-like and GRIP domain containing 5
chr15_-_26108236 0.623 NM_024490
ATP10A
ATPase, class V, type 10A
chr2_-_183902747 0.622 NCKAP1
NCK-associated protein 1
chr2_-_73339911 0.619 RAB11FIP5
RAB11 family interacting protein 5 (class I)
chr22_+_37956404 0.618 NM_152243
CDC42EP1
CDC42 effector protein (Rho GTPase binding) 1
chr13_+_48807307 0.614 ITM2B
integral membrane protein 2B
chr6_-_7910278 0.612 NM_001145549
TXNDC5
thioredoxin domain containing 5 (endoplasmic reticulum)
chr4_-_7941092 0.612 NM_001134647
NM_198595
AFAP1

actin filament associated protein 1

chr20_+_30193083 0.601 NM_002165
NM_181353
ID1

inhibitor of DNA binding 1, dominant negative helix-loop-helix protein

chr1_-_235812994 0.598 NM_001098722
GNG4
guanine nucleotide binding protein (G protein), gamma 4
chr1_+_78444922 0.598 DNAJB4
DnaJ (Hsp40) homolog, subfamily B, member 4
chr16_-_52580805 0.597 NM_001080430
TOX3
TOX high mobility group box family member 3
chr11_-_33890931 0.594 LMO2
LIM domain only 2 (rhombotin-like 1)
chr12_+_70759974 0.593 NM_014505
KCNMB4
potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr22_-_47134130 0.591 NM_022766
CERK
ceramide kinase
chr7_-_559030 0.590 PDGFA
platelet-derived growth factor alpha polypeptide
chr1_+_182992694 0.588


chr2_-_73340058 0.583 RAB11FIP5
RAB11 family interacting protein 5 (class I)
chr6_+_163835668 0.578 NM_006775
NM_206853
NM_206854
NM_206855
QKI



QKI, KH domain containing, RNA binding



chr15_+_83776323 0.574 NM_001144903
NM_023003
TM6SF1

transmembrane 6 superfamily member 1

chr7_-_95064213 0.573 NM_000305
NM_001018161
PON2

paraoxonase 2

chr1_+_99127146 0.569 NM_015976
NM_152238
SNX7

sorting nexin 7

chr9_-_74979625 0.554 ZFAND5
zinc finger, AN1-type domain 5
chr14_-_65438794 0.551 NM_198686
RAB15
RAB15, member RAS onocogene family
chr17_-_56065596 0.550 NM_007146
VEZF1
vascular endothelial zinc finger 1
chr5_-_57755787 0.550 NM_001252226
NM_006622
PLK2

polo-like kinase 2

chr16_+_58497628 0.550 NDRG4
NDRG family member 4
chr2_-_39664129 0.547 NM_003618
MAP4K3
mitogen-activated protein kinase kinase kinase kinase 3
chr17_-_74707066 0.546 MXRA7
matrix-remodelling associated 7
chr17_-_56065474 0.544 VEZF1
vascular endothelial zinc finger 1
chr17_-_80009649 0.544 NM_002917
RFNG
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr1_+_23037329 0.543 NM_004442
NM_017449
EPHB2

EPH receptor B2

chr20_+_11871364 0.542 NM_181443
BTBD3
BTB (POZ) domain containing 3
chr5_+_76011780 0.540 NM_001992
F2R
coagulation factor II (thrombin) receptor
chr9_-_16870719 0.537 NM_017637
BNC2
basonuclin 2
chr5_-_179498995 0.533 NM_018434
RNF130
ring finger protein 130
chr3_-_128207366 0.531 NM_001145661
GATA2
GATA binding protein 2
chr1_-_33168356 0.529 NM_001161708
NM_030786
SYNC

syncoilin, intermediate filament protein

chr11_-_119234628 0.529 USP2
ubiquitin specific peptidase 2

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.