Motif ID: TFAP4.p2

Z-value: 1.381


Transcription factors associated with TFAP4.p2:

Gene SymbolEntrez IDGene Name
TFAP4 7023 transcription factor AP-4 (activating enhancer binding protein 4)

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
TFAP4chr16_-_4323000,
chr16_-_4322695
0.097.4e-01Click!


Activity profile for motif TFAP4.p2.

activity profile for motif TFAP4.p2


Sorted Z-values histogram for motif TFAP4.p2

Sorted Z-values for motif TFAP4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TFAP4.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_57044980 2.823 PPAP2B
phosphatidic acid phosphatase type 2B
chr11_-_35547144 2.686 NM_001001991
NM_015430
PAMR1

peptidase domain containing associated with muscle regeneration 1

chr1_-_94702916 2.646 ARHGAP29
Rho GTPase activating protein 29
chr1_+_43996478 2.490 NM_002840
NM_130440
PTPRF

protein tyrosine phosphatase, receptor type, F

chr1_-_57045129 2.380 PPAP2B
phosphatidic acid phosphatase type 2B
chr3_-_87040246 2.368 NM_016206
VGLL3
vestigial like 3 (Drosophila)
chr8_+_97506020 2.271 SDC2
syndecan 2
chr15_+_74218962 2.082 LOXL1
lysyl oxidase-like 1
chr8_+_97506141 1.806 SDC2
syndecan 2
chr1_+_182992694 1.787


chr16_+_70502824 1.761 FUK
fucokinase
chr17_-_76921205 1.718 TIMP2
TIMP metallopeptidase inhibitor 2
chr14_-_52535737 1.701 NID2
nidogen 2 (osteonidogen)
chr1_-_57045214 1.682 PPAP2B
phosphatidic acid phosphatase type 2B
chr10_-_126849010 1.678 CTBP2
C-terminal binding protein 2
chr3_-_149688886 1.668 PFN2
profilin 2
chr7_+_17338182 1.640 NM_001621
AHR
aryl hydrocarbon receptor
chr2_-_161349874 1.603 RBMS1
RNA binding motif, single stranded interacting protein 1
chr17_-_76921076 1.548 TIMP2
TIMP metallopeptidase inhibitor 2
chr8_+_97505895 1.547 SDC2
syndecan 2
chr16_-_4166021 1.521 ADCY9
adenylate cyclase 9
chr15_+_74218786 1.514 NM_005576
LOXL1
lysyl oxidase-like 1
chr14_-_52535711 1.509 NID2
nidogen 2 (osteonidogen)
chr14_-_52535945 1.507 NM_007361
NID2
nidogen 2 (osteonidogen)
chr9_-_129884885 1.501 ANGPTL2
angiopoietin-like 2
chr15_+_74218811 1.438 LOXL1
lysyl oxidase-like 1
chr11_+_133938965 1.434 JAM3
junctional adhesion molecule 3
chr16_+_56642477 1.430 NM_005953
MT2A
metallothionein 2A
chr3_-_32023237 1.429 NM_001174060
NM_017784
OSBPL10

oxysterol binding protein-like 10

chr1_-_94147201 1.429 NM_003567
BCAR3
breast cancer anti-estrogen resistance 3
chr8_+_97506071 1.409 SDC2
syndecan 2
chr7_+_102553343 1.376 NM_001031692
NM_005824
LRRC17

leucine rich repeat containing 17

chr11_+_32112414 1.364 NM_002901
RCN1
reticulocalbin 1, EF-hand calcium binding domain
chr8_-_13134028 1.350 DLC1
deleted in liver cancer 1
chr3_-_32022734 1.346 OSBPL10
oxysterol binding protein-like 10
chr3_-_145879222 1.326 NM_000935
NM_182943
PLOD2

procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2

chr2_-_161350304 1.315 NM_002897
NM_016836
RBMS1

RNA binding motif, single stranded interacting protein 1

chr10_-_126849066 1.302 NM_001329
CTBP2
C-terminal binding protein 2
chr3_-_185542807 1.298 NM_001007225
NM_006548
IGF2BP2

insulin-like growth factor 2 mRNA binding protein 2

chr8_-_48650683 1.279 CEBPD
CCAAT/enhancer binding protein (C/EBP), delta
chr20_+_19870209 1.260 NM_018993
RIN2
Ras and Rab interactor 2
chr5_-_122372320 1.238 PPIC
peptidylprolyl isomerase C (cyclophilin C)
chr15_+_74218794 1.228 LOXL1
lysyl oxidase-like 1
chr6_-_132272311 1.220 NM_001901
CTGF
connective tissue growth factor
chr9_-_129884998 1.217 NM_012098
ANGPTL2
angiopoietin-like 2
chr19_+_3094528 1.214 GNA11
guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
chr10_+_124220990 1.214 NM_002775
HTRA1
HtrA serine peptidase 1
chr1_+_182992329 1.179 NM_002293
LAMC1
laminin, gamma 1 (formerly LAMB2)
chr5_-_122372413 1.166 NM_000943
PPIC
peptidylprolyl isomerase C (cyclophilin C)
chr3_-_133969563 1.150 NM_001005861
NM_002958
RYK

RYK receptor-like tyrosine kinase

chr16_-_4166185 1.140 NM_001116
ADCY9
adenylate cyclase 9
chrX_+_54835492 1.137 NM_201222
MAGED2
melanoma antigen family D, 2
chr3_-_124606129 1.136 NM_002213
ITGB5
integrin, beta 5
chr3_+_122785855 1.126 NM_006810
PDIA5
protein disulfide isomerase family A, member 5
chr5_-_121412805 1.125 NM_001178102
LOX
lysyl oxidase
chr12_+_13349720 1.119 EMP1
epithelial membrane protein 1
chr17_-_76921453 1.110 NM_003255
TIMP2
TIMP metallopeptidase inhibitor 2
chr13_-_114567040 1.099 NM_000820
GAS6
growth arrest-specific 6
chr3_-_124605840 1.093 ITGB5
integrin, beta 5
chr8_+_97506478 1.091 SDC2
syndecan 2
chr12_+_81471796 1.087 NM_024560
ACSS3
acyl-CoA synthetase short-chain family member 3
chr6_-_134495944 1.081 SGK1
serum/glucocorticoid regulated kinase 1
chr15_+_32933869 1.073 NM_001144757
NM_003020
SCG5

secretogranin V (7B2 protein)

chr14_+_21538339 1.066 NM_018071
ARHGEF40
Rho guanine nucleotide exchange factor (GEF) 40
chr9_+_124030413 1.064 GSN
gelsolin
chr12_-_76424474 1.046 PHLDA1
pleckstrin homology-like domain, family A, member 1
chr12_+_13349601 1.019 NM_001423
EMP1
epithelial membrane protein 1
chr3_-_149095517 1.011 NM_014220
TM4SF1
transmembrane 4 L six family member 1
chr17_-_74707000 1.008 NM_001008528
NM_001008529
NM_198530
MXRA7


matrix-remodelling associated 7


chr4_+_4861371 1.004 NM_002448
MSX1
msh homeobox 1
chr5_+_52776408 1.001 FST
follistatin
chr5_+_52776479 0.998 FST
follistatin
chr12_-_54813010 0.995 NM_002205
ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr9_+_133320093 0.993 NM_000050
NM_054012
ASS1

argininosuccinate synthase 1

chr7_-_45960738 0.990 NM_000598
NM_001013398
IGFBP3

insulin-like growth factor binding protein 3

chr2_-_158732341 0.987 NM_001111067
ACVR1
activin A receptor, type I
chr3_-_123339178 0.982 MYLK
myosin light chain kinase
chr10_+_102792166 0.976 SFXN3
sideroflexin 3
chr9_-_74383301 0.974 NM_001135820
NM_013390
TMEM2

transmembrane protein 2

chr4_+_166299942 0.969 NM_001873
CPE
carboxypeptidase E
chr13_-_114566951 0.964 GAS6
growth arrest-specific 6
chr12_-_54812936 0.957 ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr13_-_114567011 0.944 GAS6
growth arrest-specific 6
chr17_-_74707066 0.929 MXRA7
matrix-remodelling associated 7
chr7_+_130131172 0.920 NM_177525
MEST
mesoderm specific transcript homolog (mouse)
chr2_-_20212408 0.916 MATN3
matrilin 3
chr6_-_134496006 0.911 NM_005627
SGK1
serum/glucocorticoid regulated kinase 1
chr12_-_54813002 0.898 ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr10_+_102792161 0.896 SFXN3
sideroflexin 3
chr19_-_19051112 0.895 NM_001145722
NM_001145721
HOMER3

homer homolog 3 (Drosophila)

chr6_-_47277511 0.894 TNFRSF21
tumor necrosis factor receptor superfamily, member 21
chr5_-_136834887 0.888 NM_004598
SPOCK1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chr16_-_31106125 0.881 NM_024006
NM_206824
VKORC1

vitamin K epoxide reductase complex, subunit 1

chr3_-_149688638 0.880 NM_002628
NM_053024
PFN2

profilin 2

chrX_-_38079980 0.879 NM_001170750
NM_001170751
NM_001170752
NM_006307
SRPX



sushi-repeat containing protein, X-linked



chr9_+_124030455 0.879 GSN
gelsolin
chr7_+_100199881 0.878 NM_002593
PCOLCE
procollagen C-endopeptidase enhancer
chr17_+_80186281 0.875 NM_001042422
NM_001206950
SLC16A3

solute carrier family 16, member 3 (monocarboxylic acid transporter 4)

chr16_+_30386097 0.873 NM_013292
MYLPF
myosin light chain, phosphorylatable, fast skeletal muscle
chr1_-_59249687 0.864 NM_002228
JUN
jun proto-oncogene
chr16_-_31106049 0.863 VKORC1
vitamin K epoxide reductase complex, subunit 1
chr17_+_80186886 0.861 NM_004207
SLC16A3
solute carrier family 16, member 3 (monocarboxylic acid transporter 4)
chr4_+_169753105 0.860 NM_001166110
PALLD
palladin, cytoskeletal associated protein
chr6_-_47277646 0.859 NM_014452
TNFRSF21
tumor necrosis factor receptor superfamily, member 21
chr21_+_42539727 0.851 NM_012105
NM_138991
NM_138992
BACE2


beta-site APP-cleaving enzyme 2


chr16_-_31106093 0.849 VKORC1
vitamin K epoxide reductase complex, subunit 1
chr1_+_180123906 0.836 NM_001004128
NM_002826
QSOX1

quiescin Q6 sulfhydryl oxidase 1

chr1_-_120612301 0.830 NM_001200001
NM_024408
NOTCH2

notch 2

chr5_-_39425297 0.829 NM_001244871
NM_001343
DAB2

disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)

chr6_-_47277246 0.824 TNFRSF21
tumor necrosis factor receptor superfamily, member 21
chr16_-_65155881 0.818 NM_001797
CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr11_+_101980736 0.817 NM_001130145
NM_001195044
NM_006106
YAP1


Yes-associated protein 1


chr20_+_3451615 0.815 NM_001207047
NM_139321
NM_139322
ATRN


attractin


chr6_-_47277354 0.815 TNFRSF21
tumor necrosis factor receptor superfamily, member 21
chr1_+_17944810 0.808 ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr1_+_180124013 0.806 QSOX1
quiescin Q6 sulfhydryl oxidase 1
chr14_-_94856926 0.802 NM_001002235
NM_001002236
NM_001127700
NM_001127701
NM_001127702
NM_001127703
NM_001127704
NM_001127705
NM_001127706
NM_001127707
SERPINA1









serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1









chr9_-_35689799 0.800 TPM2
tropomyosin 2 (beta)
chr11_+_32112607 0.798 RCN1
reticulocalbin 1, EF-hand calcium binding domain
chr1_+_180124023 0.796 QSOX1
quiescin Q6 sulfhydryl oxidase 1
chr2_-_73339911 0.794 RAB11FIP5
RAB11 family interacting protein 5 (class I)
chr10_-_17659365 0.793 NM_014241
PTPLA
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A
chr2_-_220436010 0.784 OBSL1
obscurin-like 1
chr17_-_66453561 0.778 NM_017983
WIPI1
WD repeat domain, phosphoinositide interacting 1
chr1_+_180124031 0.775 QSOX1
quiescin Q6 sulfhydryl oxidase 1
chrX_+_154611748 0.774 NM_001007523
NM_001007524
NM_012151
F8A2
F8A3
F8A1
coagulation factor VIII-associated 2
coagulation factor VIII-associated 3
coagulation factor VIII-associated 1
chr9_+_90341030 0.773 CTSL1
cathepsin L1
chr1_-_120612019 0.772 NOTCH2
notch 2
chr19_+_33685489 0.756 NM_002333
LRP3
low density lipoprotein receptor-related protein 3
chr17_-_7017971 0.754 ASGR2
asialoglycoprotein receptor 2
chr10_-_126849556 0.753 NM_001083914
CTBP2
C-terminal binding protein 2
chr17_-_62658175 0.751 SMURF2
SMAD specific E3 ubiquitin protein ligase 2
chr19_+_33685140 0.749 LRP3
low density lipoprotein receptor-related protein 3
chr2_+_187454724 0.749 NM_001145000
NM_002210
ITGAV

integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)

chr9_+_90341022 0.739 CTSL1
cathepsin L1
chr8_+_97505876 0.738 NM_002998
SDC2
syndecan 2
chr1_-_94703252 0.733 NM_004815
ARHGAP29
Rho GTPase activating protein 29
chrX_-_128657381 0.731 SMARCA1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chr9_+_90340973 0.729 NM_001912
NM_145918
CTSL1

cathepsin L1

chr6_-_138428477 0.725 NM_022121
PERP
PERP, TP53 apoptosis effector
chr1_+_180123975 0.723 QSOX1
quiescin Q6 sulfhydryl oxidase 1
chr11_+_842821 0.721 NM_001025238
NM_001025239
NM_003271
NM_001025235
NM_001025236
TSPAN4




tetraspanin 4




chr17_-_7018049 0.721 NM_001181
NM_001201352
NM_080912
NM_080913
ASGR2



asialoglycoprotein receptor 2



chr9_-_35689902 0.716 NM_003289
NM_213674
TPM2

tropomyosin 2 (beta)

chr18_+_7567313 0.713 NM_001105244
NM_002845
PTPRM

protein tyrosine phosphatase, receptor type, M

chr16_-_31105922 0.710


chr17_-_7017558 0.707 NM_080914
ASGR2
asialoglycoprotein receptor 2
chrX_-_128657453 0.705 NM_003069
NM_139035
SMARCA1

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1

chr13_-_45150391 0.703 TSC22D1
TSC22 domain family, member 1
chrX_-_128657440 0.702 SMARCA1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chr8_+_98787808 0.698 NM_018407
LAPTM4B
lysosomal protein transmembrane 4 beta
chr11_-_8832189 0.696 NM_213618
ST5
suppression of tumorigenicity 5
chr5_-_73936299 0.695 ENC1
ectodermal-neural cortex 1 (with BTB-like domain)
chr3_-_51996855 0.695 NM_033010
PCBP4
poly(rC) binding protein 4
chr9_+_90341123 0.693 CTSL1
cathepsin L1
chr8_+_98788014 0.692 LAPTM4B
lysosomal protein transmembrane 4 beta
chr15_-_71146427 0.691 NM_018357
NM_197958
LARP6

La ribonucleoprotein domain family, member 6

chr3_-_139258531 0.686 NM_001130992
NM_001130993
NM_002899
RBP1


retinol binding protein 1, cellular


chr17_+_79651042 0.680 HGS
hepatocyte growth factor-regulated tyrosine kinase substrate
chr21_+_30452872 0.677 NM_020152
C21orf7
chromosome 21 open reading frame 7
chr17_-_62658311 0.675 NM_022739
SMURF2
SMAD specific E3 ubiquitin protein ligase 2
chr8_+_136469557 0.675 NM_006558
KHDRBS3
KH domain containing, RNA binding, signal transduction associated 3
chr12_-_106533810 0.674 NM_014840
NUAK1
NUAK family, SNF1-like kinase, 1
chr17_+_70117168 0.673 SOX9
SRY (sex determining region Y)-box 9
chr13_-_110959441 0.673 NM_001845
COL4A1
collagen, type IV, alpha 1
chr2_-_220436267 0.666 NM_001173408
NM_001173431
NM_015311
OBSL1


obscurin-like 1


chr11_+_133938819 0.662 NM_001205329
NM_032801
JAM3

junctional adhesion molecule 3

chr7_-_124405029 0.660 GPR37
G protein-coupled receptor 37 (endothelin receptor type B-like)
chr6_+_129204285 0.657 NM_000426
NM_001079823
LAMA2

laminin, alpha 2

chr9_+_124030370 0.657 NM_001127662
NM_001127663
NM_001127664
NM_001127665
NM_001127666
NM_001127667
NM_198252
GSN






gelsolin






chr4_-_80994183 0.657


chr3_-_185542744 0.654 IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr17_-_62657997 0.654 SMURF2
SMAD specific E3 ubiquitin protein ligase 2
chr10_-_3827205 0.651 KLF6
Kruppel-like factor 6
chr7_-_30029284 0.651 NM_001145515
NM_014766
NM_001145513
SCRN1


secernin 1


chr20_+_43160435 0.651 NM_007066
NM_181804
NM_181805
PKIG


protein kinase (cAMP-dependent, catalytic) inhibitor gamma


chr1_+_192778168 0.651 NM_002923
RGS2
regulator of G-protein signaling 2, 24kDa
chr8_+_136470108 0.650 KHDRBS3
KH domain containing, RNA binding, signal transduction associated 3
chr21_+_42540092 0.647 BACE2
beta-site APP-cleaving enzyme 2
chr2_-_73340058 0.640 RAB11FIP5
RAB11 family interacting protein 5 (class I)
chrX_-_154688260 0.638 NM_001007523
NM_001007524
NM_012151
F8A2
F8A3
F8A1
coagulation factor VIII-associated 2
coagulation factor VIII-associated 3
coagulation factor VIII-associated 1
chrX_-_106243442 0.634 NM_001085354
NM_024657
MORC4

MORC family CW-type zinc finger 4

chr21_+_42540054 0.631 BACE2
beta-site APP-cleaving enzyme 2
chr2_-_47168902 0.631 NM_001171508
NM_001171511
MCFD2

multiple coagulation factor deficiency 2

chr17_+_70117177 0.629 SOX9
SRY (sex determining region Y)-box 9
chr1_-_22263676 0.624 NM_005529
HSPG2
heparan sulfate proteoglycan 2
chr5_+_109025135 0.620 NM_002372
MAN2A1
mannosidase, alpha, class 2A, member 1
chr14_-_92414004 0.619 NM_006329
FBLN5
fibulin 5
chr8_+_37654833 0.609 GPR124
G protein-coupled receptor 124
chr8_+_22224786 0.608 SLC39A14
solute carrier family 39 (zinc transporter), member 14
chr11_+_65779461 0.607 NM_001323
CST6
cystatin E/M
chrX_-_51239426 0.599 NM_018159
NUDT11
nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr5_-_111093792 0.597 NM_001142477
NM_001142476
C5orf13

chromosome 5 open reading frame 13

chr8_+_37654757 0.593 GPR124
G protein-coupled receptor 124
chr11_+_67777788 0.592 NM_000694
NM_001030010
ALDH3B1

aldehyde dehydrogenase 3 family, member B1

chr5_+_102201713 0.591 PAM
peptidylglycine alpha-amidating monooxygenase
chr17_+_41003184 0.588 NM_003734
AOC3
amine oxidase, copper containing 3 (vascular adhesion protein 1)
chr19_+_3094266 0.580 NM_002067
GNA11
guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
chr1_-_110282908 0.580 GSTM3
glutathione S-transferase mu 3 (brain)
chr2_-_55277459 0.574 RTN4
reticulon 4

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.