Motif ID: TGIF1.p2

Z-value: 1.418


Transcription factors associated with TGIF1.p2:

Gene SymbolEntrez IDGene Name
TGIF1 7050 TGFB-induced factor homeobox 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
TGIF1chr18_+_3451589,
chr18_+_3449972
-0.693.1e-03Click!


Activity profile for motif TGIF1.p2.

activity profile for motif TGIF1.p2


Sorted Z-values histogram for motif TGIF1.p2

Sorted Z-values for motif TGIF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TGIF1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_-_111250156 3.421 NM_006235
POU2AF1
POU class 2 associating factor 1
chr11_-_111249902 3.278 POU2AF1
POU class 2 associating factor 1
chr6_+_32407618 2.828 NM_019111
HLA-DRA
major histocompatibility complex, class II, DR alpha
chr19_-_39826676 2.731 NM_004877
GMFG
glia maturation factor, gamma
chr19_-_39826625 2.288 GMFG
glia maturation factor, gamma
chr5_-_88199868 2.070 NM_001131005
NM_001193347
MEF2C

myocyte enhancer factor 2C

chr1_-_160681552 1.957 NM_001778
CD48
CD48 molecule
chr2_+_33661392 1.564 NM_170672
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr8_+_28174648 1.538 NM_006228
PNOC
prepronociceptin
chr14_-_106237675 1.537 IGHM
immunoglobulin heavy constant mu
chr1_+_79086087 1.518 NM_006820
IFI44L
interferon-induced protein 44-like
chr4_+_55095263 1.517 NM_006206
PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chrX_+_129305553 1.504 NM_004794
RAB33A
RAB33A, member RAS oncogene family
chr2_+_8822112 1.486 NM_002166
ID2
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
chr16_+_27413482 1.466 NM_181078
NM_181079
IL21R

interleukin 21 receptor

chr9_-_132805456 1.334 NM_015033
FNBP1
formin binding protein 1
chr15_-_48937795 1.273 NM_000138
FBN1
fibrillin 1
chr2_+_143886898 1.262 NM_018460
ARHGAP15
Rho GTPase activating protein 15
chr2_+_143886969 1.172 ARHGAP15
Rho GTPase activating protein 15
chr22_+_44395090 1.148 NM_001003828
PARVB
parvin, beta
chr7_-_94285477 1.024 NM_001099400
NM_001099401
NM_003919
SGCE


sarcoglycan, epsilon


chr20_-_20036685 1.021 NM_016652
CRNKL1
crooked neck pre-mRNA splicing factor-like 1 (Drosophila)
chr10_-_90750955 0.997 NM_001141945
ACTA2
actin, alpha 2, smooth muscle, aorta
chr3_+_45067750 0.989 NM_003278
CLEC3B
C-type lectin domain family 3, member B
chr7_-_94285426 0.981 SGCE
sarcoglycan, epsilon
chrX_-_154563735 0.980 NM_001289
CLIC2
chloride intracellular channel 2
chr11_-_119294242 0.980 NM_006288
THY1
Thy-1 cell surface antigen
chr3_-_127541975 0.951 NM_001003794
MGLL
monoglyceride lipase
chr19_-_7766978 0.926 NM_001220500
NM_002002
FCER2

Fc fragment of IgE, low affinity II, receptor for (CD23)

chr12_-_9268513 0.923 A2M
alpha-2-macroglobulin
chr7_-_137686814 0.920 NM_001253775
NM_194071
CREB3L2

cAMP responsive element binding protein 3-like 2

chr1_-_38412725 0.914 NM_005540
INPP5B
inositol polyphosphate-5-phosphatase, 75kDa
chr3_-_127541160 0.914 NM_007283
MGLL
monoglyceride lipase
chr7_-_94285372 0.906 SGCE
sarcoglycan, epsilon
chr7_-_137028533 0.865 NM_002825
PTN
pleiotrophin
chr7_+_99816870 0.849 NM_024070
PVRIG
poliovirus receptor related immunoglobulin domain containing
chr1_-_38412720 0.821 INPP5B
inositol polyphosphate-5-phosphatase, 75kDa
chr14_-_106405633 0.810 IGHM
immunoglobulin heavy constant mu
chr3_+_113251217 0.808 NM_017699
SIDT1
SID1 transmembrane family, member 1
chr8_+_98881277 0.793 NM_002380
NM_030583
MATN2

matrilin 2

chr1_-_38412667 0.778 INPP5B
inositol polyphosphate-5-phosphatase, 75kDa
chr3_+_178254223 0.777 NM_181361
KCNMB2
potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr1_+_198608136 0.762 NM_002838
NM_080921
NM_080923
PTPRC


protein tyrosine phosphatase, receptor type, C


chr1_-_38412704 0.759 INPP5B
inositol polyphosphate-5-phosphatase, 75kDa
chr14_-_107078578 0.734


chr12_-_8765438 0.725 NM_020661
AICDA
activation-induced cytidine deaminase
chr16_+_30194730 0.723 NM_001193333
NM_007074
CORO1A

coronin, actin binding protein, 1A

chr7_+_101928417 0.717 SH2B2
SH2B adaptor protein 2
chr5_-_169724817 0.713 NM_005565
LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr18_+_32556891 0.706 NM_001143826
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr14_-_23284565 0.704 SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr7_+_101928390 0.702 NM_020979
SH2B2
SH2B adaptor protein 2
chr18_-_52969714 0.702 NM_001243236
TCF4
transcription factor 4
chr7_+_119913688 0.702 NM_012281
KCND2
potassium voltage-gated channel, Shal-related subfamily, member 2
chr10_+_81073763 0.695 ZMIZ1
zinc finger, MIZ-type containing 1
chr5_-_169724734 0.678 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr7_+_94297448 0.675 PEG10
paternally expressed 10
chr16_-_4896197 0.675 GLYR1
glyoxylate reductase 1 homolog (Arabidopsis)
chr12_-_9268475 0.669 A2M
alpha-2-macroglobulin
chr12_-_109027654 0.668 NM_003006
SELPLG
selectin P ligand
chr17_+_59477169 0.653 NM_005994
TBX2
T-box 2
chr14_-_23284617 0.649 SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr12_-_109027565 0.641 SELPLG
selectin P ligand
chr3_-_121379701 0.641 HCLS1
hematopoietic cell-specific Lyn substrate 1
chr1_+_163038395 0.639 NM_001102445
RGS4
regulator of G-protein signaling 4
chr5_+_133984234 0.638 NM_001252231
NM_021982
SEC24A

SEC24 family, member A (S. cerevisiae)

chr19_+_4969123 0.631 NM_015015
KDM4B
lysine (K)-specific demethylase 4B
chr15_-_55562483 0.625 NM_183234
NM_004580
RAB27A

RAB27A, member RAS oncogene family

chr3_-_123339178 0.621 MYLK
myosin light chain kinase
chr5_-_169724782 0.621 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr15_-_66084544 0.620 NM_001144823
NM_005848
DENND4A

DENN/MADD domain containing 4A

chr3_+_4535030 0.613 NM_001099952
NM_001168272
NM_002222
ITPR1


inositol 1,4,5-trisphosphate receptor, type 1


chr7_+_94285620 0.611 NM_001040152
NM_001184961
NM_001184962
NM_015068
PEG10



paternally expressed 10



chr7_+_94285736 0.608 PEG10
paternally expressed 10
chr1_+_198608216 0.605 PTPRC
protein tyrosine phosphatase, receptor type, C
chr9_-_35650852 0.603 NM_014450
SIT1
signaling threshold regulating transmembrane adaptor 1
chr10_-_14372807 0.595 NM_018027
FRMD4A
FERM domain containing 4A
chr16_+_53479685 0.593 RBL2
retinoblastoma-like 2 (p130)
chr15_-_37391893 0.589 MEIS2
Meis homeobox 2
chr1_-_89591685 0.587 NM_004120
GBP2
guanylate binding protein 2, interferon-inducible
chr12_-_9268522 0.585 NM_000014
A2M
alpha-2-macroglobulin
chr20_+_43343523 0.584 WISP2
WNT1 inducible signaling pathway protein 2
chr11_-_78128765 0.583 GAB2
GRB2-associated binding protein 2
chr20_+_35201948 0.581 NM_021809
TGIF2
TGFB-induced factor homeobox 2
chr16_+_50776012 0.576 NM_001042412
CYLD
cylindromatosis (turban tumor syndrome)
chr16_+_50775960 0.573 NM_001042355
NM_015247
CYLD

cylindromatosis (turban tumor syndrome)

chr11_-_76380894 0.566 NM_005512
LRRC32
leucine rich repeat containing 32
chr12_-_9268440 0.562 A2M
alpha-2-macroglobulin
chr1_+_163038564 0.556 NM_005613
RGS4
regulator of G-protein signaling 4
chr15_-_43559054 0.552 NM_004245
NM_201631
TGM5

transglutaminase 5

chr4_-_42658883 0.551 NM_001105529
NM_006095
ATP8A1

ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1

chr5_-_94620277 0.549 NM_024717
MCTP1
multiple C2 domains, transmembrane 1
chr4_+_55095433 0.544 PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr2_+_97202463 0.533 NM_212481
ARID5A
AT rich interactive domain 5A (MRF1-like)
chr16_+_30194925 0.530 CORO1A
coronin, actin binding protein, 1A
chr2_+_185463092 0.530 NM_194250
ZNF804A
zinc finger protein 804A
chr17_-_66287256 0.528 NM_001174166
NM_004694
SLC16A6

solute carrier family 16, member 6 (monocarboxylic acid transporter 7)

chr12_-_109027615 0.525 SELPLG
selectin P ligand
chr3_-_121379757 0.523 NM_005335
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr15_-_66084438 0.518 DENND4A
DENN/MADD domain containing 4A
chr10_+_28822508 0.516 WAC
WW domain containing adaptor with coiled-coil
chr20_+_35201854 0.511 NM_001199513
NM_001199514
TGIF2

TGFB-induced factor homeobox 2

chr18_+_13611664 0.506 NM_001003674
NM_001003675
C18orf1

chromosome 18 open reading frame 1

chr5_+_110559647 0.504 NM_001744
CAMK4
calcium/calmodulin-dependent protein kinase IV
chr2_+_185463235 0.502 ZNF804A
zinc finger protein 804A
chr15_+_81589240 0.501 NM_004513
IL16
interleukin 16
chr4_-_105412466 0.499 NM_025212
CXXC4
CXXC finger protein 4
chr7_+_94285676 0.497 NM_001172437
NM_001172438
PEG10

paternally expressed 10

chr18_+_66465316 0.489 NM_024781
CCDC102B
coiled-coil domain containing 102B
chr17_-_26220372 0.488 NM_001076680
C17orf108
chromosome 17 open reading frame 108
chr2_+_46926049 0.485 NM_014011
SOCS5
suppressor of cytokine signaling 5
chr6_-_133078894 0.484 NM_001242350
NM_004665
VNN2

vanin 2

chr22_+_40322609 0.478 GRAP2
GRB2-related adaptor protein 2
chr1_+_156123321 0.476 NM_001193300
NM_022367
NM_001193302
SEMA4A


sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A


chr12_+_6898605 0.474 NM_000616
NM_001195014
NM_001195015
NM_001195016
NM_001195017
CD4




CD4 molecule




chr2_+_24807345 0.474 NM_003743
NM_147223
NM_147233
NCOA1


nuclear receptor coactivator 1


chr20_+_43344005 0.470 WISP2
WNT1 inducible signaling pathway protein 2
chr1_+_51435641 0.464 NM_078626
CDKN2C
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
chr9_+_125133322 0.464 PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr14_+_88471467 0.460 NM_003608
GPR65
G protein-coupled receptor 65
chr3_+_4535106 0.457 ITPR1
inositol 1,4,5-trisphosphate receptor, type 1
chr11_-_76381787 0.455 NM_001128922
LRRC32
leucine rich repeat containing 32
chr18_+_9137560 0.446 NM_001204056
ANKRD12
ankyrin repeat domain 12
chr19_+_4969126 0.439 KDM4B
lysine (K)-specific demethylase 4B
chr12_+_6898705 0.435 CD4
CD4 molecule
chr11_+_67776016 0.428 NM_001161473
ALDH3B1
aldehyde dehydrogenase 3 family, member B1
chr1_+_154966061 0.428 NM_018655
LENEP
lens epithelial protein
chr14_-_106208695 0.422


chr9_+_128510477 0.421 NM_001134778
PBX3
pre-B-cell leukemia homeobox 3
chr15_-_37391596 0.420 NM_172316
MEIS2
Meis homeobox 2
chr9_-_16727887 0.419 BNC2
basonuclin 2
chr6_-_112194648 0.419 NM_002037
FYN
FYN oncogene related to SRC, FGR, YES
chr10_-_75255718 0.418 PPP3CB
protein phosphatase 3, catalytic subunit, beta isozyme
chr11_-_78128852 0.411 NM_080491
GAB2
GRB2-associated binding protein 2
chr17_-_35969401 0.411 NM_001163544
NM_001163545
NM_001163546
NM_001163547
NM_007247
NM_080550
NM_198882
SYNRG






synergin, gamma






chr11_-_60673854 0.407 PRPF19
PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae)
chr20_+_35202956 0.403 NM_001199535
NM_001199515
TGIF2-C20ORF24
TGIF2
TGIF2-C20orf24 readthrough
TGFB-induced factor homeobox 2
chr2_-_162929928 0.400 DPP4
dipeptidyl-peptidase 4
chr6_-_112194430 0.397 FYN
FYN oncogene related to SRC, FGR, YES
chr15_-_62352565 0.394 NM_001018088
NM_017684
NM_018080
NM_020821
VPS13C



vacuolar protein sorting 13 homolog C (S. cerevisiae)



chr19_-_36643770 0.393 NM_001864
COX7A1
cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
chr12_-_49318663 0.391 NM_001143781
FKBP11
FK506 binding protein 11, 19 kDa
chr12_+_104458235 0.387 NM_013320
HCFC2
host cell factor C2
chr16_+_23847321 0.387 PRKCB
protein kinase C, beta
chr10_-_97416564 0.382 NM_001017423
NM_002860
ALDH18A1

aldehyde dehydrogenase 18 family, member A1

chr14_-_107099379 0.382 IGHG1
IGHG3
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
chr2_+_118846029 0.379 NM_016133
INSIG2
insulin induced gene 2
chr6_+_26368405 0.377 NM_001197246
BTN3A2
butyrophilin, subfamily 3, member A2
chr4_+_77870944 0.366 SEPT11
septin 11
chr3_-_123339423 0.365 NM_053031
NM_053032
MYLK

myosin light chain kinase

chr17_+_68165660 0.360 NM_000891
KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr15_+_81517639 0.359 NM_172217
IL16
interleukin 16
chr15_-_90645621 0.357 IDH2
isocitrate dehydrogenase 2 (NADP+), mitochondrial
chr14_-_106791054 0.355 IGHV4-31
IGHV3-30
IGHA1
IGHD
IGHG1
IGHG2
IGHG3
IGHM
SCFV
immunoglobulin heavy variable 4-31
immunoglobulin heavy variable 3-30
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 2 (G2m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
single-chain Fv fragment
chr12_+_108909049 0.353 NM_007076
FICD
FIC domain containing
chr1_+_51434231 0.353 NM_001262
CDKN2C
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
chr1_+_226016428 0.351 EPHX1
epoxide hydrolase 1, microsomal (xenobiotic)
chr1_-_54871978 0.350 NM_018070
NM_145716
SSBP3

single stranded DNA binding protein 3

chr6_-_26235160 0.349 NM_005320
HIST1H1D
histone cluster 1, H1d
chr2_-_162930544 0.348 DPP4
dipeptidyl-peptidase 4
chr19_+_1067114 0.348 NM_012292
HMHA1
histocompatibility (minor) HA-1
chr14_+_100150596 0.347 NM_006668
CYP46A1
cytochrome P450, family 46, subfamily A, polypeptide 1
chr13_-_34250899 0.346 NM_001243476
STARD13
StAR-related lipid transfer (START) domain containing 13
chr15_-_90645704 0.344 NM_002168
IDH2
isocitrate dehydrogenase 2 (NADP+), mitochondrial
chr6_-_131384387 0.344 NM_001135554
NM_001135555
NM_001199388
NM_001431
EPB41L2



erythrocyte membrane protein band 4.1-like 2



chr1_+_101702304 0.343 NM_001400
S1PR1
sphingosine-1-phosphate receptor 1
chr7_+_150413597 0.343 NM_001199577
NM_130759
GIMAP1-GIMAP5
GIMAP1
GIMAP1-GIMAP5 readthrough
GTPase, IMAP family member 1
chr3_+_69788562 0.341 NM_198159
MITF
microphthalmia-associated transcription factor
chr17_+_16319087 0.341 TRPV2
transient receptor potential cation channel, subfamily V, member 2
chr14_-_106237486 0.339


chr10_+_28822428 0.339 WAC
WW domain containing adaptor with coiled-coil
chr1_-_202129705 0.337 PTPN7
protein tyrosine phosphatase, non-receptor type 7
chr9_+_125132823 0.337 PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr9_+_2622099 0.333 VLDLR
very low density lipoprotein receptor
chr15_+_43809805 0.333 NM_002373
MAP1A
microtubule-associated protein 1A
chr10_+_124768401 0.332 NM_001609
ACADSB
acyl-CoA dehydrogenase, short/branched chain
chr13_-_38172862 0.328 NM_001135934
NM_001135935
NM_001135936
NM_006475
POSTN



periostin, osteoblast specific factor



chr11_+_6411637 0.328 NM_000543
NM_001007593
SMPD1

sphingomyelin phosphodiesterase 1, acid lysosomal

chr12_+_59989847 0.326 SLC16A7
solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
chr3_-_129325175 0.325 NM_015103
PLXND1
plexin D1
chr12_-_92539614 0.325 NM_001731
BTG1
B-cell translocation gene 1, anti-proliferative
chr9_+_116207010 0.322 NM_144488
RGS3
regulator of G-protein signaling 3
chr15_-_90645709 0.321 IDH2
isocitrate dehydrogenase 2 (NADP+), mitochondrial
chr12_+_111843743 0.320 NM_005475
SH2B3
SH2B adaptor protein 3
chrX_+_46940235 0.317 RGN
regucalcin (senescence marker protein-30)
chr1_-_54871681 0.317 SSBP3
single stranded DNA binding protein 3
chr1_-_160832466 0.315 NM_001166663
NM_001166664
NM_016382
CD244


CD244 molecule, natural killer cell receptor 2B4


chr2_-_191872322 0.315 STAT1
signal transducer and activator of transcription 1, 91kDa
chr19_+_1067536 0.314 HMHA1
histocompatibility (minor) HA-1
chr22_-_37882214 0.314 NM_001166343
NM_002405
MFNG

MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

chr19_+_41903723 0.313 BCKDHA
branched chain keto acid dehydrogenase E1, alpha polypeptide
chr1_-_173176314 0.310 NM_003326
TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr12_-_91572328 0.309 NM_133504
NM_133505
NM_133506
NM_133507
DCN



decorin



chr1_+_65613771 0.309 NM_013410
AK4
adenylate kinase 4
chr10_-_23003036 0.308 PIP4K2A
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
chr10_+_63808968 0.308 NM_001244638
ARID5B
AT rich interactive domain 5B (MRF1-like)
chr7_+_120590816 0.307 NM_019071
NM_198267
ING3

inhibitor of growth family, member 3

chr8_-_102803438 0.307 NM_032041
NCALD
neurocalcin delta
chr3_-_49066760 0.305 IMPDH2
IMP (inosine 5'-monophosphate) dehydrogenase 2
chr9_-_95244634 0.304 ASPN
asporin

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.