Motif ID: UCCAGUU

Z-value: 2.244


Mature miRNA associated with seed UCCAGUU:

NamemiRBase Accession
hsa-miR-145 MIMAT0000437



Activity profile for motif UCCAGUU.

activity profile for motif UCCAGUU


Sorted Z-values histogram for motif UCCAGUU

Sorted Z-values for motif UCCAGUU



Network of associatons between targets according to the STRING database.



First level regulatory network of UCCAGUU

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_+_151646634 8.096 NM_144497
 AKAP12
A kinase (PRKA) anchor protein 12
chr6_+_151561094 7.775 NM_005100
 AKAP12
A kinase (PRKA) anchor protein 12
chr5_-_39425297 7.512 NM_001244871
NM_001343
 DAB2

disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)

chr12_-_106533810 6.946 NM_014840
 NUAK1
NUAK family, SNF1-like kinase, 1
chr7_+_130126035 6.591 NM_177524
 MEST
mesoderm specific transcript homolog (mouse)
chr5_-_121412805 6.424 NM_001178102
 LOX
lysyl oxidase
chr1_+_86046434 6.237 NM_001554
 CYR61
cysteine-rich, angiogenic inducer, 61
chr8_-_12973752 6.168 NM_001164271
 DLC1
deleted in liver cancer 1
chr8_-_12990731 6.051 NM_006094
 DLC1
deleted in liver cancer 1
chr7_+_130131172 5.710 NM_177525
 MEST
mesoderm specific transcript homolog (mouse)
chr7_+_130131921 5.487 NM_002402
 MEST
mesoderm specific transcript homolog (mouse)
chr1_-_94703252 5.335 NM_004815
 ARHGAP29
Rho GTPase activating protein 29
chrX_-_99891690 4.921 NM_003270
 TSPAN6
tetraspanin 6
chr12_+_78225068 4.781 NM_014903
 NAV3
neuron navigator 3
chr5_-_121414011 4.736 NM_002317
 LOX
lysyl oxidase
chr7_+_100770378 4.459 NM_000602
NM_001165413
 SERPINE1

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

chr2_+_9346876 4.345 NM_001135191
NM_003887
 ASAP2

ArfGAP with SH3 domain, ankyrin repeat and PH domain 2

chr7_-_131241321 4.078 NM_001018111
NM_005397
 PODXL

podocalyxin-like

chr3_+_30647901 3.491 NM_001024847
NM_003242
 TGFBR2

transforming growth factor, beta receptor II (70/80kDa)

chr12_-_89746244 3.367 NM_001946
NM_022652
 DUSP6

dual specificity phosphatase 6


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 19 of 19 entries
Enrichment   P-value GO Accession GO Term
47.44 1.77e-02 GO:0034446 substrate adhesion-dependent cell spreading
43.13 2.42e-02 GO:0048009 insulin-like growth factor receptor signaling pathway
7.59 2.28e-02 GO:0001525 angiogenesis
7.46 1.89e-03 GO:0048514 blood vessel morphogenesis
7.00 2.62e-04 GO:0001944 vasculature development
6.83 1.15e-03 GO:0001568 blood vessel development
5.20 6.38e-04 GO:0072358 cardiovascular system development
5.20 6.38e-04 GO:0072359 circulatory system development
4.66 5.36e-03 GO:0009967 positive regulation of signal transduction
4.43 8.88e-03 GO:0010647 positive regulation of cell communication
4.41 9.30e-03 GO:0023056 positive regulation of signaling
3.47 2.11e-05 GO:0009966 regulation of signal transduction
3.34 3.84e-02 GO:0048584 positive regulation of response to stimulus
3.17 1.06e-02 GO:0010646 regulation of cell communication
3.13 7.35e-05 GO:0023051 regulation of signaling
2.84 5.02e-03 GO:0009653 anatomical structure morphogenesis
2.68 1.43e-03 GO:0048583 regulation of response to stimulus
2.12 3.70e-03 GO:0048856 anatomical structure development
1.91 1.84e-02 GO:0032502 developmental process

Gene overrepresentation in compartment category:

Showing 1 to 4 of 4 entries
Enrichment   P-value GO Accession GO Term
31.63 1.47e-02 GO:0016010 dystrophin-associated glycoprotein complex
10.84 1.33e-02 GO:0030027 lamellipodium
7.97 9.61e-04 GO:0031252 cell leading edge
6.94 3.11e-02 GO:0045121 membrane raft

Gene overrepresentation in function category:

Showing 1 to 3 of 3 entries
Enrichment   P-value GO Accession GO Term
5.85 9.34e-04 GO:0003779 actin binding
3.94 1.25e-02 GO:0008092 cytoskeletal protein binding
1.41 4.68e-02 GO:0005515 protein binding