Motif ID: UGUGCUU

Z-value: 1.536


Mature miRNA associated with seed UGUGCUU:

NamemiRBase Accession
hsa-miR-218 MIMAT0000275



Activity profile for motif UGUGCUU.

activity profile for motif UGUGCUU


Sorted Z-values histogram for motif UGUGCUU

Sorted Z-values for motif UGUGCUU



Network of associatons between targets according to the STRING database.



First level regulatory network of UGUGCUU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr18_-_11148760 3.109 NM_022068
PIEZO2
piezo-type mechanosensitive ion channel component 2
chr5_-_88199868 2.620 NM_001131005
NM_001193347
MEF2C

myocyte enhancer factor 2C

chr5_-_88179278 2.598 NM_001193350
NM_002397
MEF2C

myocyte enhancer factor 2C

chr12_-_56652118 2.210 NM_173595
ANKRD52
ankyrin repeat domain 52
chr4_-_40631846 2.158 NM_001098634
RBM47
RNA binding motif protein 47
chr19_-_41196419 1.977 NM_004756
NUMBL
numb homolog (Drosophila)-like
chr20_-_4804067 1.966 NM_014737
RASSF2
Ras association (RalGDS/AF-6) domain family member 2
chr20_-_4795768 1.798 NM_170774
RASSF2
Ras association (RalGDS/AF-6) domain family member 2
chr15_-_61521478 1.700 NM_134261
RORA
RAR-related orphan receptor A
chr7_-_1595746 1.699 NM_001097620
TMEM184A
transmembrane protein 184A
chr15_-_60884615 1.698 NM_134262
RORA
RAR-related orphan receptor A
chr7_-_37488554 1.689 NM_014800
ELMO1
engulfment and cell motility 1
chr7_-_103629962 1.602 NM_005045
NM_173054
RELN

reelin

chr3_+_16974581 1.598 NM_015184
PLCL2
phospholipase C-like 2
chr7_-_37393271 1.596 NM_001206482
ELMO1
engulfment and cell motility 1
chr3_+_16926451 1.595 NM_001144382
PLCL2
phospholipase C-like 2
chr14_-_89883306 1.579 NM_005197
FOXN3
forkhead box N3
chr10_+_80828776 1.527 NM_020338
ZMIZ1
zinc finger, MIZ-type containing 1
chr8_+_38644721 1.515 NM_001122824
NM_006283
TACC1

transforming, acidic coiled-coil containing protein 1

chr7_+_50344255 1.511 NM_001220765
NM_001220766
NM_001220767
NM_001220768
NM_001220769
NM_001220770
NM_001220771
NM_001220772
NM_001220773
NM_001220774
NM_001220775
NM_001220776
NM_006060
IKZF1












IKAROS family zinc finger 1 (Ikaros)












chr3_-_171177851 1.488 NM_001161560
NM_001161561
NM_001161562
NM_001161563
NM_001161564
NM_001161565
NM_001161566
NM_015028
TNIK







TRAF2 and NCK interacting kinase







chr1_-_154842725 1.480 NM_001204087
NM_002249
KCNN3

potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3

chr8_+_38585703 1.480 NM_001146216
TACC1
transforming, acidic coiled-coil containing protein 1
chr15_-_60919642 1.478 NM_002943
NM_134260
RORA

RAR-related orphan receptor A

chr1_+_213123853 1.471 NM_001136474
NM_001136475
NM_024749
VASH2


vasohibin 2


chr7_-_37488894 1.459 NM_001206480
ELMO1
engulfment and cell motility 1
chr5_-_88119604 1.393 NM_001193348
NM_001193349
MEF2C

myocyte enhancer factor 2C

chr7_-_37024664 1.347 NM_001039459
ELMO1
engulfment and cell motility 1
chr4_-_40517913 1.343 NM_019027
RBM47
RNA binding motif protein 47
chr17_+_53342320 1.322 NM_002126
HLF
hepatic leukemia factor
chr1_-_200992824 1.292 NM_001252100
NM_001252102
NM_001252103
NM_017596
KIF21B



kinesin family member 21B



chr1_-_21978287 1.267 NM_001145658
RAP1GAP
RAP1 GTPase activating protein
chr2_+_231729501 1.236 NM_001012514
NM_001012516
NM_030926
ITM2C


integral membrane protein 2C


chr3_-_125239049 1.205 NM_003794
SNX4
sorting nexin 4
chr13_+_103451398 1.200 NM_001159596
NM_017693
BIVM

basic, immunoglobulin-like variable motif containing

chr11_-_78128852 1.186 NM_080491
GAB2
GRB2-associated binding protein 2
chr8_-_70745624 1.182 NM_001146008
SLCO5A1
solute carrier organic anion transporter family, member 5A1
chr1_-_21995793 1.169 NM_001145657
NM_002885
RAP1GAP

RAP1 GTPase activating protein

chr9_-_36400212 1.166 NM_022781
NM_194329
RNF38

ring finger protein 38

chr9_-_36400817 1.157 NM_194328
NM_194332
RNF38

ring finger protein 38

chr9_-_36401149 1.144 NM_194330
RNF38
ring finger protein 38
chr18_+_13218777 1.125 NM_181481
NM_181482
C18orf1

chromosome 18 open reading frame 1

chr17_-_46507481 1.109 NM_001075099
NM_003726
SKAP1

src kinase associated phosphoprotein 1

chr18_+_13620866 1.097 NM_004338
NM_181483
C18orf1

chromosome 18 open reading frame 1

chr5_+_126112314 1.087 NM_005573
LMNB1
lamin B1
chr22_-_39548448 1.057 NM_175709
CBX7
chromobox homolog 7
chr18_+_13611664 1.051 NM_001003674
NM_001003675
C18orf1

chromosome 18 open reading frame 1

chr8_-_70745403 1.045 NM_001146009
SLCO5A1
solute carrier organic anion transporter family, member 5A1
chr2_-_20527120 1.040 NM_015317
PUM2
pumilio homolog 2 (Drosophila)
chr22_+_21271619 1.033 NM_005207
CRKL
v-crk sarcoma virus CT10 oncogene homolog (avian)-like
chr3_-_101395611 1.030 NM_014415
ZBTB11
zinc finger and BTB domain containing 11
chr6_-_7910716 1.017 NM_030810
TXNDC5
thioredoxin domain containing 5 (endoplasmic reticulum)
chr11_-_78052925 1.011 NM_012296
GAB2
GRB2-associated binding protein 2
chr11_-_35441099 1.008 NM_004171
SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr3_-_53079285 0.995 NM_001005159
SFMBT1
Scm-like with four mbt domains 1
chr11_-_72852957 0.990 NM_014824
FCHSD2
FCH and double SH3 domains 2
chr5_+_126112819 0.979 NM_001198557
LMNB1
lamin B1
chr16_+_68119211 0.974 NM_004555
NM_173163
NM_173165
NFATC3


nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3


chr3_+_167453431 0.964 NM_001122752
NM_005025
SERPINI1

serpin peptidase inhibitor, clade I (neuroserpin), member 1

chr20_+_35201948 0.964 NM_021809
TGIF2
TGFB-induced factor homeobox 2
chr18_+_55102777 0.963 NM_004852
ONECUT2
one cut homeobox 2
chr22_+_21771661 0.958 NM_015094
HIC2
hypermethylated in cancer 2
chr12_-_25055966 0.945 NM_001178093
BCAT1
branched chain amino-acid transaminase 1, cytosolic
chr1_+_167298280 0.939 NM_001198783
POU2F1
POU class 2 homeobox 1
chr1_+_167189948 0.938 NM_001198786
NM_002697
POU2F1

POU class 2 homeobox 1

chr2_-_64881040 0.928 NM_014755
SERTAD2
SERTA domain containing 2
chr6_-_7910278 0.910 NM_001145549
TXNDC5
thioredoxin domain containing 5 (endoplasmic reticulum)
chr1_+_28844647 0.908 NM_001048194
NM_001048195
NM_001269
RCC1


regulator of chromosome condensation 1


chr7_+_119913688 0.894 NM_012281
KCND2
potassium voltage-gated channel, Shal-related subfamily, member 2
chr3_+_151985828 0.893 NM_021038
NM_207292
MBNL1

muscleblind-like (Drosophila)

chr14_-_90085325 0.887 NM_001085471
FOXN3
forkhead box N3
chr2_-_200322699 0.886 NM_001172509
SATB2
SATB homeobox 2
chr11_-_35441501 0.882 NM_001195728
NM_001252652
SLC1A2

solute carrier family 1 (glial high affinity glutamate transporter), member 2

chr20_+_35201854 0.870 NM_001199513
NM_001199514
TGIF2

TGFB-induced factor homeobox 2

chr20_+_34742656 0.855 NM_012156
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr14_+_92788924 0.855 NM_153648
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr17_+_5185551 0.849 NM_001083585
NM_004703
RABEP1

rabaptin, RAB GTPase binding effector protein 1

chr3_-_184870727 0.837 NM_001025266
C3orf70
chromosome 3 open reading frame 70
chr12_-_131002409 0.834 NM_015347
RIMBP2
RIMS binding protein 2
chr4_+_129730772 0.832 NM_024900
NM_199320
PHF17

PHD finger protein 17

chr3_+_152017193 0.827 NM_207293
NM_207294
NM_207295
NM_207296
NM_207297
MBNL1




muscleblind-like (Drosophila)




chr1_+_65613211 0.826 NM_203464
NM_001005353
AK4

adenylate kinase 4

chr2_-_69614321 0.812 NM_001244710
NM_002056
GFPT1

glutamine--fructose-6-phosphate transaminase 1

chr8_-_70747200 0.811 NM_030958
SLCO5A1
solute carrier organic anion transporter family, member 5A1
chr14_+_92789536 0.810 NM_153647
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr12_-_25055228 0.809 NM_001178094
BCAT1
branched chain amino-acid transaminase 1, cytosolic
chr15_+_74907334 0.800 NM_001130028
CLK3
CDC-like kinase 3
chr18_-_6414900 0.788 NM_173464
L3MBTL4
l(3)mbt-like 4 (Drosophila)
chr1_+_65613771 0.778 NM_013410
AK4
adenylate kinase 4
chr16_-_52580805 0.776 NM_001080430
TOX3
TOX high mobility group box family member 3
chr2_-_152955208 0.765 NM_001005746
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr2_-_152955502 0.751 NM_000726
NM_001145798
CACNB4

calcium channel, voltage-dependent, beta 4 subunit

chr12_-_25102281 0.747 NM_001178091
NM_001178092
NM_005504
BCAT1


branched chain amino-acid transaminase 1, cytosolic


chr11_+_121322848 0.739 NM_003105
SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr5_+_61601944 0.736 NM_001098511
NM_001243952
NM_001243953
NM_004520
KIF2A



kinesin heavy chain member 2A



chr9_-_127905715 0.735 NM_001144877
NM_173690
SCAI

suppressor of cancer cell invasion

chr1_+_28832454 0.732 NM_001048199
RCC1
regulator of chromosome condensation 1
chr12_+_94542239 0.732 NM_005761
PLXNC1
plexin C1
chr17_-_79881304 0.730 NM_032711
MAFG
v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)
chr1_+_36348795 0.728 NM_012199
EIF2C1
eukaryotic translation initiation factor 2C, 1
chr8_-_82024277 0.724 NM_018440
PAG1
phosphoprotein associated with glycosphingolipid microdomains 1
chr18_+_2655885 0.706 NM_015295
SMCHD1
structural maintenance of chromosomes flexible hinge domain containing 1
chr5_+_127419407 0.700 NM_001046
SLC12A2
solute carrier family 12 (sodium/potassium/chloride transporters), member 2
chr17_-_48785016 0.682 NM_052855
ANKRD40
ankyrin repeat domain 40
chr3_-_182698291 0.679 NM_020640
DCUN1D1
DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae)
chr7_-_138665853 0.678 NM_001164665
NM_020910
KIAA1549

KIAA1549

chr14_+_92790151 0.677 NM_153646
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr21_+_45285101 0.669 NM_020132
AGPAT3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr11_-_70507911 0.663 NM_133266
SHANK2
SH3 and multiple ankyrin repeat domains 2
chr15_+_74900712 0.656 NM_003992
CLK3
CDC-like kinase 3
chr17_+_60556247 0.655 NM_001112707
NM_006852
TLK2

tousled-like kinase 2

chr2_-_200329810 0.654 NM_001172517
SATB2
SATB homeobox 2
chrX_-_20284708 0.653 NM_004586
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr9_+_112403067 0.650 NM_001037293
PALM2
paralemmin 2
chr7_+_100026412 0.649 NM_001194990
NM_001194991
NM_001194992
MEPCE


methylphosphate capping enzyme


chr10_-_14372807 0.640 NM_018027
FRMD4A
FERM domain containing 4A
chr17_-_76356153 0.635 NM_003955
SOCS3
suppressor of cytokine signaling 3
chr16_-_52581713 0.632 NM_001146188
TOX3
TOX high mobility group box family member 3
chr20_+_48552902 0.623 NM_018683
RNF114
ring finger protein 114
chr1_+_211499956 0.622 NM_004619
TRAF5
TNF receptor-associated factor 5
chr6_+_12012723 0.617 NM_002114
HIVEP1
human immunodeficiency virus type I enhancer binding protein 1
chrX_+_108780058 0.614 NM_001242617
NXT2
nuclear transport factor 2-like export factor 2
chr1_+_211500147 0.611 NM_001033910
TRAF5
TNF receptor-associated factor 5
chr15_+_78441678 0.611 NM_005530
IDH3A
isocitrate dehydrogenase 3 (NAD+) alpha
chr1_-_154832187 0.610 NM_170782
KCNN3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr3_-_150480963 0.609 NM_005067
SIAH2
seven in absentia homolog 2 (Drosophila)
chr2_+_32288579 0.607 NM_014946
NM_199436
SPAST

spastin

chr8_-_81083660 0.605 NM_001025253
NM_005079
TPD52

tumor protein D52

chr8_-_80993009 0.601 NM_001025252
TPD52
tumor protein D52
chr22_+_45560529 0.601 NM_153645
NUP50
nucleoporin 50kDa
chr5_-_115910406 0.599 NM_020796
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr19_-_14316980 0.598 NM_001008701
NM_014921
LPHN1

latrophilin 1

chr2_-_152830448 0.596 NM_001005747
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr21_+_35445808 0.587 NM_032476
NM_006933
MRPS6
SLC5A3
mitochondrial ribosomal protein S6
solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
chr1_-_153940187 0.587 NM_014437
SLC39A1
solute carrier family 39 (zinc transporter), member 1
chr1_+_44870926 0.584 NM_018150
RNF220
ring finger protein 220
chr2_-_55646946 0.581 NM_001135597
NM_018084
CCDC88A

coiled-coil domain containing 88A

chr5_+_67586466 0.579 NM_181504
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chrX_+_108779009 0.577 NM_018698
NXT2
nuclear transport factor 2-like export factor 2
chr5_+_133861685 0.573 NM_015288
PHF15
PHD finger protein 15
chr4_+_160188997 0.573 NM_014247
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr2_-_200335988 0.572 NM_015265
SATB2
SATB homeobox 2
chr10_+_22610138 0.571 NM_005180
BMI1
BMI1 polycomb ring finger oncogene
chr9_-_91793681 0.570 NM_016848
SHC3
SHC (Src homology 2 domain containing) transforming protein 3
chr7_+_106685007 0.567 NM_002736
PRKAR2B
protein kinase, cAMP-dependent, regulatory, type II, beta
chrX_-_15873094 0.566 NM_003916
AP1S2
adaptor-related protein complex 1, sigma 2 subunit
chr2_-_73496595 0.565 NM_001080410
FBXO41
F-box protein 41
chr15_+_91643181 0.564 NM_001167580
SV2B
synaptic vesicle glycoprotein 2B
chr12_-_58240746 0.560 NM_005730
CTDSP2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr1_+_211519705 0.559 NM_145759
TRAF5
TNF receptor-associated factor 5
chr19_-_33166057 0.556 NM_032139
ANKRD27
ankyrin repeat domain 27 (VPS9 domain)
chr6_+_64281910 0.551 NM_003463
PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr2_-_128100673 0.537 NM_006609
MAP3K2
mitogen-activated protein kinase kinase kinase 2
chr22_+_25960738 0.535 NM_005160
ADRBK2
adrenergic, beta, receptor kinase 2
chr6_+_150920998 0.531 NM_001029884
PLEKHG1
pleckstrin homology domain containing, family G (with RhoGef domain) member 1
chr15_+_91643429 0.530 NM_014848
SV2B
synaptic vesicle glycoprotein 2B
chr7_-_22396511 0.528 NM_012294
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr11_-_47545539 0.524 NM_001172639
CELF1
CUGBP, Elav-like family member 1
chr13_+_76334796 0.518 NM_015842
LMO7
LIM domain 7
chrX_+_108780235 0.516 NM_001242618
NXT2
nuclear transport factor 2-like export factor 2
chr5_-_1524022 0.509 NM_024830
LPCAT1
lysophosphatidylcholine acyltransferase 1
chr2_-_61697846 0.509 NM_014709
USP34
ubiquitin specific peptidase 34
chr3_+_39093480 0.503 NM_020839
WDR48
WD repeat domain 48
chr7_+_98476084 0.500 NM_001244580
NM_003496
TRRAP

transformation/transcription domain-associated protein

chr4_+_38665587 0.496 NM_016531
KLF3
Kruppel-like factor 3 (basic)
chr13_-_79233266 0.494 NM_024546
RNF219
ring finger protein 219
chr2_+_208394615 0.489 NM_004379
NM_134442
CREB1

cAMP responsive element binding protein 1

chr1_-_235490801 0.487 NM_001206794
ARID4B
AT rich interactive domain 4B (RBP1-like)
chr7_+_100027253 0.485 NM_019606
MEPCE
methylphosphate capping enzyme
chr4_+_87856152 0.484 NM_001166693
AFF1
AF4/FMR2 family, member 1
chr16_+_19535178 0.483 NM_001199022
NM_014711
CCP110

centriolar coiled coil protein 110kDa

chr11_-_70935807 0.479 NM_012309
SHANK2
SH3 and multiple ankyrin repeat domains 2
chr5_-_160975124 0.473 NM_000813
NM_021911
GABRB2

gamma-aminobutyric acid (GABA) A receptor, beta 2

chr3_+_140660639 0.469 NM_001104647
NM_018155
SLC25A36

solute carrier family 25, member 36

chr12_+_5019048 0.464 NM_000217
KCNA1
potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)
chr3_+_124303505 0.464 NM_007064
KALRN
kalirin, RhoGEF kinase
chr6_-_32157511 0.460 NM_002586
PBX2
pre-B-cell leukemia homeobox 2
chr4_+_87928083 0.457 NM_005935
AFF1
AF4/FMR2 family, member 1
chr13_+_36050885 0.455 NM_001204197
NBEA
neurobeachin
chr12_-_54653317 0.450 NM_001127322
CBX5
chromobox homolog 5
chr12_+_12869818 0.450 NM_004064
CDKN1B
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
chr6_-_24911194 0.444 NM_014722
FAM65B
family with sequence similarity 65, member B
chr1_+_36396673 0.443 NM_024852
NM_177422
EIF2C3

eukaryotic translation initiation factor 2C, 3

chr2_+_121103670 0.440 NM_002193
INHBB
inhibin, beta B
chr7_-_112727832 0.434 NM_001146265
NM_018970
GPR85

G protein-coupled receptor 85

chr11_+_66886735 0.434 NM_012308
KDM2A
lysine (K)-specific demethylase 2A
chr20_+_62887046 0.432 NM_001104925
NM_018257
PCMTD2

protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2

chr1_+_93544786 0.432 NM_001164391
NM_001164392
NM_001164393
NM_007358
MTF2



metal response element binding transcription factor 2



chrX_+_24167728 0.430 NM_001178086
NM_001178095
NM_001178084
NM_001178085
NM_003410
ZFX




zinc finger protein, X-linked




chr11_+_119020298 0.426 NM_001142505
ABCG4
ATP-binding cassette, sub-family G (WHITE), member 4
chr9_+_34958171 0.425 NM_015297
KIAA1045
KIAA1045
chr8_+_125486949 0.419 NM_007218
RNF139
ring finger protein 139
chr5_-_32313069 0.414 NM_001040446
MTMR12
myotubularin related protein 12
chr12_-_24715349 0.414 NM_152989
SOX5
SRY (sex determining region Y)-box 5
chr10_-_21463019 0.413 NM_001173484
NM_213569
NEBL

nebulette

chr6_-_143266283 0.413 NM_006734
HIVEP2
human immunodeficiency virus type I enhancer binding protein 2
chr5_+_65440004 0.412 NM_001077199
SREK1
splicing regulatory glutamine/lysine-rich protein 1
chr17_+_37026111 0.410 NM_006148
LASP1
LIM and SH3 protein 1
chrX_-_73834460 0.410 NM_016120
NM_183353
RLIM

ring finger protein, LIM domain interacting

chr12_-_54653369 0.406 NM_001127321
CBX5
chromobox homolog 5

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.