Motif ID: UUGGUCC

Z-value: 1.320


Mature miRNA associated with seed UUGGUCC:

NamemiRBase Accession
hsa-miR-133a MIMAT0000427
hsa-miR-133b MIMAT0000770



Activity profile for motif UUGGUCC.

activity profile for motif UUGGUCC


Sorted Z-values histogram for motif UUGGUCC

Sorted Z-values for motif UUGGUCC



Network of associatons between targets according to the STRING database.



First level regulatory network of UUGGUCC

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_+_33359607 2.757 NM_000627
NM_001166264
NM_001166265
NM_001166266
LTBP1



latent transforming growth factor beta binding protein 1



chr2_+_33172368 2.677 NM_206943
LTBP1
latent transforming growth factor beta binding protein 1
chr10_-_126849066 2.443 NM_001329
CTBP2
C-terminal binding protein 2
chr10_-_126716452 2.385 NM_022802
CTBP2
C-terminal binding protein 2
chr10_-_126849556 2.158 NM_001083914
CTBP2
C-terminal binding protein 2
chr5_-_127873734 2.149 NM_001999
FBN2
fibrillin 2
chr1_-_159895279 2.066 NM_003564
TAGLN2
transgelin 2
chr13_-_40177355 1.901 NM_005780
LHFP
lipoma HMGIC fusion partner
chrX_-_140271293 1.881 NM_012317
LDOC1
leucine zipper, down-regulated in cancer 1
chr9_-_14398981 1.692 NM_001190738
NFIB
nuclear factor I/B
chr8_-_93029864 1.591 NM_175636
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr9_-_14314036 1.557 NM_001190737
NM_005596
NFIB

nuclear factor I/B

chr3_-_168865521 1.487 NM_001164000
MECOM
MDS1 and EVI1 complex locus
chr6_-_134498973 1.447 NM_001143677
SGK1
serum/glucocorticoid regulated kinase 1
chr4_-_114900802 1.445 NM_024590
ARSJ
arylsulfatase family, member J
chr6_-_132272311 1.438 NM_001901
CTGF
connective tissue growth factor
chr6_-_134639195 1.429 NM_001143676
SGK1
serum/glucocorticoid regulated kinase 1
chr8_-_93115453 1.389 NM_001198633
NM_175634
RUNX1T1

runt-related transcription factor 1; translocated to, 1 (cyclin D-related)

chr3_-_168864325 1.355 NM_001105078
MECOM
MDS1 and EVI1 complex locus
chrX_+_64887510 1.344 NM_002444
MSN
moesin
chr8_-_93111915 1.333 NM_001198628
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr6_-_134496006 1.330 NM_005627
SGK1
serum/glucocorticoid regulated kinase 1
chr8_-_93107881 1.298 NM_001198625
NM_001198626
NM_001198627
NM_001198631
NM_001198634
NM_001198679
RUNX1T1





runt-related transcription factor 1; translocated to, 1 (cyclin D-related)





chr6_-_134497069 1.290 NM_001143678
SGK1
serum/glucocorticoid regulated kinase 1
chr1_+_7831326 1.217 NM_004781
VAMP3
vesicle-associated membrane protein 3 (cellubrevin)
chr8_-_93075190 1.212 NM_004349
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr11_-_9025531 1.178 NM_020645
NRIP3
nuclear receptor interacting protein 3
chr3_-_168864066 1.170 NM_001105077
NM_001163999
NM_005241
MECOM


MDS1 and EVI1 complex locus


chr2_-_56151273 1.124 NM_001039348
NM_001039349
EFEMP1

EGF containing fibulin-like extracellular matrix protein 1

chr7_-_27205148 1.121 NM_152739
HOXA9
homeobox A9
chr3_-_107809754 1.112 NM_001777
NM_198793
CD47

CD47 molecule

chr12_+_10365415 1.109 NM_031412
GABARAPL1
GABA(A) receptor-associated protein like 1
chr3_+_33318911 1.092 NM_012157
NM_001171713
FBXL2

F-box and leucine-rich repeat protein 2

chr8_-_93107442 1.077 NM_001198629
NM_001198630
NM_001198632
NM_175635
RUNX1T1



runt-related transcription factor 1; translocated to, 1 (cyclin D-related)



chr14_-_23388380 1.056 NM_001077351
NM_001077352
NM_018107
RBM23


RNA binding motif protein 23


chr4_+_86699846 1.054 NM_001042669
ARHGAP24
Rho GTPase activating protein 24
chr2_+_66662516 1.050 NM_002398
MEIS1
Meis homeobox 1
chr6_+_21593963 1.045 NM_003107
SOX4
SRY (sex determining region Y)-box 4
chr4_+_86851425 0.971 NM_031305
ARHGAP24
Rho GTPase activating protein 24
chrX_+_107069081 0.964 NM_012216
NM_052817
MID2

midline 2

chr1_-_183604885 0.960 NM_005717
ARPC5
actin related protein 2/3 complex, subunit 5, 16kDa
chr4_-_7941092 0.948 NM_001134647
NM_198595
AFAP1

actin filament associated protein 1

chr15_-_23086290 0.929 NM_144599
NIPA1
non imprinted in Prader-Willi/Angelman syndrome 1
chr15_-_48937795 0.923 NM_000138
FBN1
fibrillin 1
chr4_+_86396251 0.922 NM_001025616
ARHGAP24
Rho GTPase activating protein 24
chr6_+_1610680 0.908 NM_001453
FOXC1
forkhead box C1
chr17_-_39942937 0.850 NM_002230
NM_021991
JUP

junction plakoglobin

chr10_-_104262404 0.843 NM_005736
ACTR1A
ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)
chr15_+_52121807 0.803 NM_014547
TMOD3
tropomodulin 3 (ubiquitous)
chr1_-_208417635 0.800 NM_025179
PLXNA2
plexin A2
chr2_-_26205437 0.785 NM_002254
KIF3C
kinesin family member 3C
chr1_-_209825797 0.777 NM_000228
LAMB3
laminin, beta 3
chr19_+_16178170 0.756 NM_001145160
TPM4
tropomyosin 4
chr1_-_209824641 0.755 NM_001017402
LAMB3
laminin, beta 3
chr1_-_209825673 0.749 NM_001127641
LAMB3
laminin, beta 3
chr19_+_16187047 0.738 NM_003290
TPM4
tropomyosin 4
chr6_+_125475334 0.728 NM_001003395
TPD52L1
tumor protein D52-like 1
chr17_+_60704747 0.707 NM_006039
MRC2
mannose receptor, C type 2
chr2_-_1748285 0.697 NM_012293
PXDN
peroxidasin homolog (Drosophila)
chr3_-_160822625 0.694 NM_033169
NM_001038628
NM_003781
NM_033167
NM_033168
B3GALNT1




beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)




chr6_+_125474800 0.682 NM_001003396
NM_001003397
NM_003287
TPD52L1


tumor protein D52-like 1


chr15_-_37392358 0.671 NM_170674
NM_170675
NM_170676
NM_170677
MEIS2



Meis homeobox 2



chr11_-_17191287 0.668 NM_002645
PIK3C2A
phosphoinositide-3-kinase, class 2, alpha polypeptide
chr7_+_5632435 0.630 NM_003088
FSCN1
fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
chr19_+_1026271 0.628 NM_004368
NM_201277
CNN2

calponin 2

chr6_+_11538486 0.619 NM_001100829
TMEM170B
transmembrane protein 170B
chr12_+_122516555 0.618 NM_014938
MLXIP
MLX interacting protein
chr15_-_37393364 0.617 NM_001220482
NM_002399
MEIS2

Meis homeobox 2

chr3_-_149688638 0.612 NM_002628
NM_053024
PFN2

profilin 2

chr20_+_11898536 0.610 NM_014962
BTBD3
BTB (POZ) domain containing 3
chr12_+_72666462 0.609 NM_013381
TRHDE
thyrotropin-releasing hormone degrading enzyme
chr15_-_37390372 0.608 NM_172315
MEIS2
Meis homeobox 2
chr22_+_25202135 0.606 NM_001039948
NM_001098497
NM_001098498
NM_133454
SGSM1



small G protein signaling modulator 1



chr12_-_106641675 0.596 NM_006825
CKAP4
cytoskeleton-associated protein 4
chr3_+_183892569 0.595 NM_001025205
NM_004068
AP2M1

adaptor-related protein complex 2, mu 1 subunit

chr1_+_201924618 0.588 NM_006335
TIMM17A
translocase of inner mitochondrial membrane 17 homolog A (yeast)
chr6_-_138428477 0.586 NM_022121
PERP
PERP, TP53 apoptosis effector
chr1_-_36184727 0.582 NM_152374
C1orf216
chromosome 1 open reading frame 216
chr1_-_205180691 0.567 NM_015375
NM_199462
DSTYK

dual serine/threonine and tyrosine protein kinase

chr3_+_25469833 0.561 NM_000965
RARB
retinoic acid receptor, beta
chr17_-_1359410 0.556 NM_005206
NM_016823
CRK

v-crk sarcoma virus CT10 oncogene homolog (avian)

chr9_+_36190852 0.555 NM_001076677
NM_001184760
NM_001184761
NM_001184762
NM_001833
NM_007096
CLTA





clathrin, light chain A





chr9_-_124132503 0.547 NM_004099
NM_198194
STOM

stomatin

chr5_+_95997871 0.545 NM_001042440
CAST
calpastatin
chr3_-_15798057 0.540 NM_001195099
ANKRD28
ankyrin repeat domain 28
chr20_+_11871364 0.511 NM_181443
BTBD3
BTB (POZ) domain containing 3
chr3_-_15839674 0.504 NM_001195098
ANKRD28
ankyrin repeat domain 28
chr2_-_161350304 0.504 NM_002897
NM_016836
RBMS1

RNA binding motif, single stranded interacting protein 1

chr4_-_177713664 0.499 NM_005429
VEGFC
vascular endothelial growth factor C
chr17_-_41174431 0.491 NM_006373
VAT1
vesicle amine transport protein 1 homolog (T. californica)
chr9_+_116226006 0.485 NM_017790
RGS3
regulator of G-protein signaling 3
chr7_+_121513158 0.482 NM_001206838
NM_001206839
NM_002851
PTPRZ1


protein tyrosine phosphatase, receptor-type, Z polypeptide 1


chr5_+_95997723 0.471 NM_001190442
CAST
calpastatin
chr22_-_28315214 0.456 NM_012399
PITPNB
phosphatidylinositol transfer protein, beta
chr15_-_37391596 0.454 NM_172316
MEIS2
Meis homeobox 2
chr5_+_96038492 0.448 NM_173060
CAST
calpastatin
chr4_+_1283662 0.446 NM_001017405
NM_005882
MAEA

macrophage erythroblast attacher

chr12_+_56137063 0.445 NM_005811
GDF11
growth differentiation factor 11
chr15_+_96875793 0.440 NM_001145156
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr10_+_6186758 0.431 NM_001145443
PFKFB3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr15_+_96876568 0.421 NM_001145157
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr15_+_96869156 0.419 NM_001145155
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr8_+_22409226 0.418 NM_005775
SORBS3
sorbin and SH3 domain containing 3
chr12_-_105629790 0.416 NM_001251904
NM_018171
APPL2

adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2

chr1_+_170633312 0.414 NM_006902
NM_022716
PRRX1

paired related homeobox 1

chr6_-_80656870 0.413 NM_022726
ELOVL4
ELOVL fatty acid elongase 4
chr3_-_32544358 0.412 NM_017801
CMTM6
CKLF-like MARVEL transmembrane domain containing 6
chrX_+_153665258 0.410 NM_001493
GDI1
GDP dissociation inhibitor 1
chr3_+_45730677 0.408 NM_014016
SACM1L
SAC1 suppressor of actin mutations 1-like (yeast)
chr14_+_90863302 0.406 NM_006888
CALM1
calmodulin 1 (phosphorylase kinase, delta)
chr3_-_52090090 0.405 NM_001947
DUSP7
dual specificity phosphatase 7
chr10_-_104473957 0.404 NM_004311
ARL3
ADP-ribosylation factor-like 3
chr11_+_12399024 0.403 NM_018222
PARVA
parvin, alpha
chr12_-_26277807 0.403 NM_030762
BHLHE41
basic helix-loop-helix family, member e41
chr16_-_66584045 0.400 NM_001172643
NM_001172644
NM_001172645
NM_004614
TK2



thymidine kinase 2, mitochondrial



chr12_+_56521953 0.399 NM_001184796
NM_015292
ESYT1

extended synaptotagmin-like protein 1

chr22_-_36784055 0.398 NM_002473
MYH9
myosin, heavy chain 9, non-muscle
chr3_-_15900928 0.397 NM_015199
ANKRD28
ankyrin repeat domain 28
chr1_-_149889362 0.388 NM_014849
SV2A
synaptic vesicle glycoprotein 2A
chr11_-_75062650 0.382 NM_004041
NM_020251
ARRB1

arrestin, beta 1

chr3_+_43328001 0.369 NM_001100594
NM_017719
SNRK

SNF related kinase

chr5_-_178157597 0.366 NM_005649
ZNF354A
zinc finger protein 354A
chr18_-_812268 0.359 NM_005433
YES1
v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1
chr1_+_32573619 0.358 NM_012316
KPNA6
karyopherin alpha 6 (importin alpha 7)
chr13_-_110438896 0.350 NM_003749
IRS2
insulin receptor substrate 2
chr12_+_79258448 0.346 NM_005639
SYT1
synaptotagmin I
chr7_+_30951414 0.344 NM_198098
AQP1
aquaporin 1 (Colton blood group)
chr20_+_43104513 0.342 NM_001039199
NM_024331
TTPAL

tocopherol (alpha) transfer protein-like

chr15_+_96873845 0.340 NM_021005
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr14_+_69658193 0.330 NM_001193360
NM_001193361
NM_018199
EXD2


exonuclease 3'-5' domain containing 2


chr10_+_60272868 0.330 NM_001080512
BICC1
bicaudal C homolog 1 (Drosophila)
chr6_-_128841432 0.327 NM_002844
NM_001135648
PTPRK

protein tyrosine phosphatase, receptor type, K

chr8_+_22423170 0.323 NM_001018003
SORBS3
sorbin and SH3 domain containing 3
chr6_-_84140854 0.322 NM_002395
ME1
malic enzyme 1, NADP(+)-dependent, cytosolic
chr14_+_23305792 0.321 NM_004995
MMP14
matrix metallopeptidase 14 (membrane-inserted)
chr18_+_33234532 0.320 NM_020474
GALNT1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1)
chrX_-_48931645 0.314 NM_007213
PRAF2
PRA1 domain family, member 2
chr12_+_79439432 0.312 NM_001135806
SYT1
synaptotagmin I
chrX_-_37706816 0.310 NM_006520
DYNLT3
dynein, light chain, Tctex-type 3
chr3_-_185542807 0.307 NM_001007225
NM_006548
IGF2BP2

insulin-like growth factor 2 mRNA binding protein 2

chr1_+_117910052 0.307 NM_006699
MAN1A2
mannosidase, alpha, class 1A, member 2
chr11_+_35639734 0.304 NM_014344
FJX1
four jointed box 1 (Drosophila)
chr7_-_42276617 0.300 NM_000168
GLI3
GLI family zinc finger 3
chr8_-_22926490 0.292 NM_003842
NM_147187
TNFRSF10B

tumor necrosis factor receptor superfamily, member 10b

chr10_+_6244839 0.291 NM_004566
PFKFB3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr9_-_101470836 0.289 NM_005458
GABBR2
gamma-aminobutyric acid (GABA) B receptor, 2
chr11_-_89322778 0.289 NM_001143837
NOX4
NADPH oxidase 4
chr13_-_29069215 0.286 NM_001159920
NM_001160030
NM_001160031
NM_002019
FLT1



fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)



chr5_+_140739589 0.285 NM_018923
NM_032096
PCDHGB2

protocadherin gamma subfamily B, 2

chr4_-_96470350 0.285 NM_003728
UNC5C
unc-5 homolog C (C. elegans)
chr3_-_46608039 0.285 NM_024512
LRRC2
leucine rich repeat containing 2
chr13_+_58205788 0.284 NM_001040429
PCDH17
protocadherin 17
chr12_+_79257772 0.284 NM_001135805
SYT1
synaptotagmin I
chr6_-_7910278 0.284 NM_001145549
TXNDC5
thioredoxin domain containing 5 (endoplasmic reticulum)
chr5_+_140797243 0.284 NM_018927
PCDHGB7
protocadherin gamma subfamily B, 7
chr19_+_19322763 0.283 NM_004386
NCAN
neurocan
chr8_-_38326351 0.281 NM_001174063
NM_001174064
NM_015850
NM_023105
NM_023106
NM_023110
FGFR1





fibroblast growth factor receptor 1





chr14_+_69658482 0.281 NM_001193362
NM_001193363
EXD2

exonuclease 3'-5' domain containing 2

chr10_+_71211215 0.281 NM_012339
TSPAN15
tetraspanin 15
chr5_+_34687663 0.278 NM_001145523
RAI14
retinoic acid induced 14
chr11_-_6502563 0.278 NM_001242854
NM_001242855
NM_001242856
NM_012402
ARFIP2



ADP-ribosylation factor interacting protein 2



chr5_+_140868721 0.277 NM_018929
NM_032407
PCDHGC5

protocadherin gamma subfamily C, 5

chr10_+_89419352 0.276 NM_001015880
NM_004670
PAPSS2

3'-phosphoadenosine 5'-phosphosulfate synthase 2

chr8_-_30670323 0.275 NM_001009552
PPP2CB
protein phosphatase 2, catalytic subunit, beta isozyme
chr9_-_16870719 0.273 NM_017637
BNC2
basonuclin 2
chr5_+_34656595 0.272 NM_001145520
RAI14
retinoic acid induced 14
chr5_+_140749830 0.272 NM_018924
NM_032097
PCDHGB3

protocadherin gamma subfamily B, 3

chr5_+_34656367 0.271 NM_001145522
NM_015577
RAI14

retinoic acid induced 14

chr6_+_134274247 0.267 NM_004865
TBPL1
TBP-like 1
chr1_+_25870043 0.267 NM_015627
LDLRAP1
low density lipoprotein receptor adaptor protein 1
chr7_+_28475233 0.264 NM_004904
CREB5
cAMP responsive element binding protein 5
chr11_-_89224413 0.261 NM_001143836
NM_016931
NOX4

NADPH oxidase 4

chr7_-_100425035 0.261 NM_004444
EPHB4
EPH receptor B4
chr11_-_61584451 0.258 NM_013402
FADS1
fatty acid desaturase 1
chr1_+_218458628 0.258 NM_016052
RRP15
ribosomal RNA processing 15 homolog (S. cerevisiae)
chr5_+_34684611 0.257 NM_001145521
NM_001145525
RAI14

retinoic acid induced 14

chr19_+_41305333 0.253 NM_053046
EGLN2
egl nine homolog 2 (C. elegans)
chrX_-_119709618 0.250 NM_003588
CUL4B
cullin 4B
chr4_+_111397181 0.250 NM_001977
ENPEP
glutamyl aminopeptidase (aminopeptidase A)
chr5_+_140864626 0.249 NM_018928
NM_032406
PCDHGC4

protocadherin gamma subfamily C, 4

chrX_+_40440145 0.247 NM_005765
ATP6AP2
ATPase, H+ transporting, lysosomal accessory protein 2
chr3_-_45267804 0.247 NM_015444
TMEM158
transmembrane protein 158 (gene/pseudogene)
chr17_-_40307015 0.246 NM_001252039
NM_004583
NM_201434
RAB5C


RAB5C, member RAS oncogene family


chr9_+_131873592 0.245 NM_178000
NM_178001
NM_178003
PPP2R4


protein phosphatase 2A activator, regulatory subunit 4


chr19_+_41305041 0.245 NM_080732
EGLN2
egl nine homolog 2 (C. elegans)
chr4_+_52709165 0.245 NM_001040402
NM_015115
DCUN1D4

DCN1, defective in cullin neddylation 1, domain containing 4 (S. cerevisiae)

chr15_-_77712436 0.243 NM_024776
PEAK1
NKF3 kinase family member
chr1_-_179198814 0.241 NM_001136001
NM_001168236
NM_001168237
NM_001168238
NM_007314
ABL2




v-abl Abelson murine leukemia viral oncogene homolog 2




chr9_+_101867401 0.239 NM_001130916
NM_004612
TGFBR1

transforming growth factor, beta receptor 1

chr5_+_140729723 0.238 NM_018922
NM_032095
PCDHGB1

protocadherin gamma subfamily B, 1

chr5_+_140810126 0.238 NM_003735
NM_032094
PCDHGA12

protocadherin gamma subfamily A, 12

chr11_+_67351065 0.238 NM_000852
GSTP1
glutathione S-transferase pi 1
chr1_+_29213569 0.237 NM_001166005
NM_001166007
NM_004437
NM_203342
NM_203343
EPB41




erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)




chr21_+_22370622 0.234 NM_004540
NCAM2
neural cell adhesion molecule 2
chr1_+_40506254 0.232 NM_001105530
NM_006367
CAP1

CAP, adenylate cyclase-associated protein 1 (yeast)

chr5_-_142065586 0.230 NM_000800
FGF1
fibroblast growth factor 1 (acidic)
chr6_-_7910716 0.230 NM_030810
TXNDC5
thioredoxin domain containing 5 (endoplasmic reticulum)
chr3_-_169381417 0.230 NM_001205194
NM_004991
MECOM

MDS1 and EVI1 complex locus

chr19_-_37019169 0.229 NM_001012756
NM_001166036
NM_001166037
NM_001166038
ZNF260



zinc finger protein 260



chr14_-_23623493 0.226 NM_182728
SLC7A8
solute carrier family 7 (amino acid transporter light chain, L system), member 8

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
351.37 1.65e-03 GO:0035581 extracellular sequestering of receptor ligand
351.37 1.65e-03 GO:0035583 negative regulation of transforming growth factor beta receptor signaling pathway by extracellular sequestering of TGFbeta
351.37 1.65e-03 GO:0071692 protein localization in extracellular region
351.37 1.65e-03 GO:0071694 maintenance of protein location in extracellular region
150.61 1.15e-02 GO:0060216 definitive hemopoiesis

Nothing significant found in compartment category.

Nothing significant found in function category.