Motif ID: VSX1,2.p2

Z-value: 0.450


Transcription factors associated with VSX1,2.p2:

Gene SymbolEntrez IDGene Name
VSX1 30813 visual system homeobox 1
VSX2 338917 visual system homeobox 2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
VSX1chr20_-_250627560.048.9e-01Click!


Activity profile for motif VSX1,2.p2.

activity profile for motif VSX1,2.p2


Sorted Z-values histogram for motif VSX1,2.p2

Sorted Z-values for motif VSX1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of VSX1,2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_169418167 2.066 NM_001166108
NM_016081
PALLD

palladin, cytoskeletal associated protein

chrX_+_43515406 0.923 NM_000240
MAOA
monoamine oxidase A
chr16_+_55515468 0.743 NM_001127891
MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chrX_+_43515441 0.735 MAOA
monoamine oxidase A
chr2_-_217560247 0.529 NM_000599
IGFBP5
insulin-like growth factor binding protein 5
chr12_+_28410132 0.524 NM_018318
CCDC91
coiled-coil domain containing 91
chr11_-_118135197 0.466 NM_005797
NM_144765
MPZL2

myelin protein zero-like 2

chr3_-_126327397 0.458 NM_001039783
TXNRD3NB
thioredoxin reductase 3 neighbor
chr6_+_121756744 0.410 NM_000165
GJA1
gap junction protein, alpha 1, 43kDa
chr18_+_61554938 0.377 NM_001143818
NM_002575
SERPINB2

serpin peptidase inhibitor, clade B (ovalbumin), member 2

chr11_-_120008801 0.375 TRIM29
tripartite motif containing 29
chr12_-_53012332 0.311 NM_175068
KRT73
keratin 73
chr7_-_81399286 0.309 NM_000601
NM_001010931
NM_001010932
NM_001010933
NM_001010934
HGF




hepatocyte growth factor (hepapoietin A; scatter factor)




chr1_-_68697997 0.306 NM_001002292
NM_001193334
NM_024911
WLS


wntless homolog (Drosophila)


chrX_+_43515531 0.291 MAOA
monoamine oxidase A
chr5_-_39394423 0.277 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr12_-_91505215 0.243 LUM
lumican
chr8_-_86290333 0.235 NM_001128829
NM_001128830
NM_001128831
NM_001738
CA1



carbonic anhydrase I



chr6_+_90276556 0.228 NM_001242814
ANKRD6
ankyrin repeat domain 6
chr3_+_159557649 0.228 NM_001197109
SCHIP1
schwannomin interacting protein 1
chr11_-_4414887 0.228 NM_003141
TRIM21
tripartite motif containing 21
chr11_+_59824054 0.212 NM_001031666
NM_001031809
NM_006138
MS4A3


membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)


chr6_-_47253962 0.201 TNFRSF21
tumor necrosis factor receptor superfamily, member 21
chr1_+_147425566 0.162 NM_001097616
GPR89C
G protein-coupled receptor 89C
chr11_-_118134956 0.162 MPZL2
myelin protein zero-like 2
chr2_+_189839132 0.161 COL3A1
collagen, type III, alpha 1
chr3_+_69985750 0.161 NM_000248
NM_001184968
NM_198158
NM_198178
MITF



microphthalmia-associated transcription factor



chr8_+_54764367 0.155 NM_170587
RGS20
regulator of G-protein signaling 20
chr7_-_83824216 0.146 NM_006080
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr2_+_189839113 0.141 COL3A1
collagen, type III, alpha 1
chr2_-_175712276 0.138 NM_001206602
CHN1
chimerin (chimaerin) 1
chr11_-_118134986 0.137 MPZL2
myelin protein zero-like 2
chr18_+_3447607 0.136 NM_173207
TGIF1
TGFB-induced factor homeobox 1
chr15_-_37393364 0.131 NM_001220482
NM_002399
MEIS2

Meis homeobox 2

chr11_-_120008738 0.124 TRIM29
tripartite motif containing 29
chr7_+_2557496 0.121 NM_002304
LFNG
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr1_+_81771844 0.114 LPHN2
latrophilin 2
chr5_+_71403040 0.112 NM_005909
MAP1B
microtubule-associated protein 1B
chr10_+_18689512 0.111 NM_201570
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr4_-_169239816 0.103 NM_017631
DDX60
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
chr1_+_151735444 0.103 NM_001134939
OAZ3
ornithine decarboxylase antizyme 3
chr9_+_132897342 0.101 GPR107
G protein-coupled receptor 107
chr12_-_52828105 0.100 NM_004693
KRT75
keratin 75
chr4_+_70796798 0.096 NM_001025104
NM_001890
CSN1S1

casein alpha s1

chr15_-_55563091 0.094 NM_183236
RAB27A
RAB27A, member RAS oncogene family
chr6_-_111888520 0.094 NM_001164283
TRAF3IP2
TRAF3 interacting protein 2
chr1_+_177140062 0.088 FAM5B
family with sequence similarity 5, member B
chr6_-_46293628 0.081 NM_005822
RCAN2
regulator of calcineurin 2
chr9_+_21440452 0.079 NM_024013
IFNA1
interferon, alpha 1
chr1_+_28261503 0.075 NM_001009568
NM_014474
SMPDL3B

sphingomyelin phosphodiesterase, acid-like 3B

chr3_+_111717585 0.075 NM_001008272
NM_013259
TAGLN3

transgelin 3

chr8_-_62602285 0.073 NM_001164750
NM_001164751
NM_001164752
NM_001164753
NM_020164
NM_032467
NM_032468
ASPH






aspartate beta-hydroxylase






chr4_-_72669757 0.072 NM_001204307
GC
group-specific component (vitamin D binding protein)
chr1_-_200377262 0.071 ZNF281
zinc finger protein 281
chr4_-_123377471 0.071 NM_000586
IL2
interleukin 2
chr11_+_59824129 0.070 MS4A3
membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr11_-_17191287 0.069 NM_002645
PIK3C2A
phosphoinositide-3-kinase, class 2, alpha polypeptide
chr4_-_122137781 0.065 NM_001128843
TNIP3
TNFAIP3 interacting protein 3
chr14_+_32798478 0.062 NM_004274
AKAP6
A kinase (PRKA) anchor protein 6
chr16_-_20338808 0.060 NM_001007240
NM_001007241
NM_001007242
NM_001502
GP2



glycoprotein 2 (zymogen granule membrane)



chr14_+_67831484 0.060 EIF2S1
eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
chr10_+_96443250 0.057 NM_000772
NM_001128925
CYP2C18

cytochrome P450, family 2, subfamily C, polypeptide 18

chr15_-_42749710 0.054 NM_022473
ZFP106
zinc finger protein 106 homolog (mouse)
chr14_+_61201450 0.054 NM_001177963
NM_002431
MNAT1

menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis)

chr1_-_205325915 0.052 NM_018203
KLHDC8A
kelch domain containing 8A
chr3_-_164796275 0.050 NM_001041
SI
sucrase-isomaltase (alpha-glucosidase)
chr8_+_19796581 0.050 NM_000237
LPL
lipoprotein lipase
chr14_-_78083109 0.049 NM_004863
SPTLC2
serine palmitoyltransferase, long chain base subunit 2
chr10_-_69455926 0.044 NM_013266
CTNNA3
catenin (cadherin-associated protein), alpha 3
chr1_+_160160284 0.044 NM_001231
CASQ1
calsequestrin 1 (fast-twitch, skeletal muscle)
chr4_+_5526882 0.044 NM_005750
C4orf6
chromosome 4 open reading frame 6
chr10_-_33224485 0.043 NM_033668
ITGB1
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
chr1_+_117544371 0.042 NM_004258
CD101
CD101 molecule
chr4_-_39979549 0.042 NM_001100399
NM_001100400
PDS5A

PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)

chr22_-_18923963 0.039 NM_001195226
NM_016335
PRODH

proline dehydrogenase (oxidase) 1

chr9_-_21202201 0.039 NM_021057
IFNA7
interferon, alpha 7
chr10_+_32856650 0.035 NM_024688
C10orf68
chromosome 10 open reading frame 68
chr11_+_60048013 0.033 NM_001243266
NM_024021
NM_148975
MS4A4A


membrane-spanning 4-domains, subfamily A, member 4


chr3_+_108541544 0.031 NM_016388
TRAT1
T cell receptor associated transmembrane adaptor 1
chr5_-_9630462 0.031 NM_019599
TAS2R1
taste receptor, type 2, member 1
chr8_+_9413390 0.031 TNKS
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr15_-_55562483 0.028 NM_183234
NM_004580
RAB27A

RAB27A, member RAS oncogene family

chr6_+_29079586 0.027 NM_001005216
OR2J3
olfactory receptor, family 2, subfamily J, member 3
chr12_-_4488707 0.027 NM_020638
FGF23
fibroblast growth factor 23
chr7_+_129008044 0.027 AHCYL2
adenosylhomocysteinase-like 2
chrX_-_23925947 0.026 NM_024122
APOO
apolipoprotein O
chr18_-_53089722 0.026 NM_001243233
TCF4
transcription factor 4
chr2_-_219031646 0.026 NM_000634
CXCR1
chemokine (C-X-C motif) receptor 1
chr1_-_190446701 0.026 NM_199051
FAM5C
family with sequence similarity 5, member C
chr10_+_5136613 0.025 AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr1_-_93257950 0.024 NM_005665
EVI5
ecotropic viral integration site 5
chr6_+_28317687 0.024 NM_001242894
NM_001242895
NM_024493
ZKSCAN3


zinc finger with KRAB and SCAN domains 3


chr12_-_71031174 0.023 NM_001109754
PTPRB
protein tyrosine phosphatase, receptor type, B
chr4_-_39979159 0.021 PDS5A
PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)
chr9_+_116356199 0.021 NM_144489
RGS3
regulator of G-protein signaling 3
chr17_-_29624249 0.021 NM_002544
OMG
oligodendrocyte myelin glycoprotein
chr18_-_51690988 0.019 MBD2
methyl-CpG binding domain protein 2
chr11_-_115088628 0.017 CADM1
cell adhesion molecule 1
chr10_+_95372344 0.017 NM_006204
PDE6C
phosphodiesterase 6C, cGMP-specific, cone, alpha prime
chr10_+_18549583 0.017 NM_000724
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr11_-_114466397 0.016 FAM55D
family with sequence similarity 55, member D
chr4_-_72649734 0.016 NM_000583
GC
group-specific component (vitamin D binding protein)
chr18_+_46065367 0.016 NM_001142397
NM_014772
CTIF

CBP80/20-dependent translation initiation factor

chr3_-_167191808 0.014 NM_006217
SERPINI2
serpin peptidase inhibitor, clade I (pancpin), member 2
chr12_-_56106061 0.013 NM_001144997
ITGA7
integrin, alpha 7
chr7_-_99774821 0.012 NM_152742
GPC2
glypican 2
chr12_+_18414473 0.012 NM_004570
PIK3C2G
phosphoinositide-3-kinase, class 2, gamma polypeptide
chr12_+_10460416 0.012 NM_002262
NM_007334
KLRD1

killer cell lectin-like receptor subfamily D, member 1

chrX_-_151619669 0.011 NM_000808
GABRA3
gamma-aminobutyric acid (GABA) A receptor, alpha 3
chr4_-_89978117 0.011 NM_014883
FAM13A
family with sequence similarity 13, member A
chr7_+_141811508 0.008 LOC93432
maltase-glucoamylase (alpha-glucosidase) pseudogene
chr3_+_151985828 0.008 NM_021038
NM_207292
MBNL1

muscleblind-like (Drosophila)

chr1_-_157746863 0.008 NM_030764
FCRL2
Fc receptor-like 2
chr8_-_87755880 0.007 NM_019098
CNGB3
cyclic nucleotide gated channel beta 3
chr13_-_36050758 0.006 NM_005584
MAB21L1
mab-21-like 1 (C. elegans)
chr6_+_29426130 0.006 NM_030883
OR2H1
olfactory receptor, family 2, subfamily H, member 1
chr11_+_89764273 0.006 NM_001195234
TRIM49L2
tripartite motif containing 49-like 2
chr12_-_58135853 0.005 NM_014770
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chrX_-_138790328 0.005 NM_001099855
NM_001171876
MCF2

MCF.2 cell line derived transforming sequence

chr11_+_45115563 0.003 NM_020229
PRDM11
PR domain containing 11
chr6_+_27925018 0.003 NM_012367
OR2B6
olfactory receptor, family 2, subfamily B, member 6
chr10_-_48416692 0.003 NM_016204
GDF2
growth differentiation factor 2
chr2_+_109204745 0.003 NM_004987
LIMS1
LIM and senescent cell antigen-like domains 1
chr6_+_160542862 0.003 NM_003057
NM_153187
SLC22A1

solute carrier family 22 (organic cation transporter), member 1

chr2_-_37374948 0.002 NM_001135652
EIF2AK2
eukaryotic translation initiation factor 2-alpha kinase 2
chrX_-_107334749 0.002 NM_002814
NM_170750
PSMD10

proteasome (prosome, macropain) 26S subunit, non-ATPase, 10

chr11_-_89541742 0.000 NM_020358
TRIM49
tripartite motif containing 49

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.