Motif ID: ZBTB16.p2

Z-value: 1.892


Transcription factors associated with ZBTB16.p2:

Gene SymbolEntrez IDGene Name
ZBTB16 7704 zinc finger and BTB domain containing 16

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
ZBTB16chr11_+_113931228,
chr11_+_113930430,
chr11_+_113930296		0.009.9e-01Click!


Activity profile for motif ZBTB16.p2.

activity profile for motif ZBTB16.p2


Sorted Z-values histogram for motif ZBTB16.p2

Sorted Z-values for motif ZBTB16.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZBTB16.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_198608136 6.154 NM_002838
NM_080921
NM_080923
 PTPRC


protein tyrosine phosphatase, receptor type, C


chr12_-_53601051 5.972 ITGB7
integrin, beta 7
chr7_+_26400503 5.775 NM_001199837
 SNX10
sorting nexin 10
chr1_+_198608216 5.129 PTPRC
protein tyrosine phosphatase, receptor type, C
chr12_-_53600999 4.712 NM_000889
 ITGB7
integrin, beta 7
chr1_+_198608244 4.168 PTPRC
protein tyrosine phosphatase, receptor type, C
chr13_-_99959649 3.777 NM_004951
 GPR183
G protein-coupled receptor 183
chr19_-_48759141 3.499 NM_001184902
NM_001184904
 CARD8

caspase recruitment domain family, member 8

chr13_-_46756291 3.358 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr2_-_89292396 3.355 IGKC
immunoglobulin kappa constant
chr13_-_99910548 3.340 NM_001098200
NM_005292
 GPR18

G protein-coupled receptor 18

chr19_-_48752921 3.324 NM_001184901
NM_001184903
NM_014959
 CARD8


caspase recruitment domain family, member 8


chr16_+_81812899 2.879 PLCG2
phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr16_+_81812897 2.848 NM_002661
 PLCG2
phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr22_+_23229959 2.823 NM_001178126
 IGLL5
IGLC1
immunoglobulin lambda-like polypeptide 5
immunoglobulin lambda constant 1 (Mcg marker)
chr6_+_12717036 2.735 NM_001242648
NM_030948
 PHACTR1

phosphatase and actin regulator 1

chr3_-_15382874 2.582 NM_001018009
 SH3BP5
SH3-domain binding protein 5 (BTK-associated)
chr8_-_80993009 2.373 NM_001025252
 TPD52
tumor protein D52
chr2_+_33661392 2.364 NM_170672
 RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr1_+_174844655 2.352 NM_001035230
 RABGAP1L
RAB GTPase activating protein 1-like

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 42 entries
Enrichment   P-value GO Accession GO Term
48.04 1.60e-02 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB cascade
40.04 2.91e-02 GO:0043372 positive regulation of CD4-positive, alpha-beta T cell differentiation
40.04 2.91e-02 GO:2000516 positive regulation of CD4-positive, alpha-beta T cell activation
37.68 1.84e-03 GO:0050853 B cell receptor signaling pathway
25.63 9.44e-03 GO:0030890 positive regulation of B cell proliferation
24.64 1.11e-02 GO:0002285 lymphocyte activation involved in immune response
19.07 3.45e-03 GO:0002263 cell activation involved in immune response
19.07 3.45e-03 GO:0002366 leukocyte activation involved in immune response
18.85 3.32e-02 GO:0030888 regulation of B cell proliferation
14.24 4.74e-05 GO:0050851 antigen receptor-mediated signaling pathway
13.08 9.24e-05 GO:0002429 immune response-activating cell surface receptor signaling pathway
12.72 2.58e-02 GO:0002449 lymphocyte mediated immunity
12.69 1.17e-04 GO:0002768 immune response-regulating cell surface receptor signaling pathway
12.42 3.85e-06 GO:0002252 immune effector process
12.33 3.00e-02 GO:0042113 B cell activation
11.96 3.47e-02 GO:0050671 positive regulation of lymphocyte proliferation
11.78 3.73e-02 GO:0032946 positive regulation of mononuclear cell proliferation
11.73 2.03e-07 GO:0002757 immune response-activating signal transduction
11.61 4.00e-02 GO:0070665 positive regulation of leukocyte proliferation
11.52 2.51e-07 GO:0002764 immune response-regulating signaling pathway

Nothing significant found in compartment category.

Gene overrepresentation in function category:

Showing 1 to 7 of 7 entries
Enrichment   P-value GO Accession GO Term
28.27 1.53e-02 GO:0001608 nucleotide receptor activity, G-protein coupled
28.27 1.53e-02 GO:0045028 purinergic nucleotide receptor activity, G-protein coupled
28.03 4.47e-07 GO:0003823 antigen binding
20.03 4.42e-02 GO:0001614 purinergic nucleotide receptor activity
20.03 4.42e-02 GO:0016502 nucleotide receptor activity
9.21 2.10e-02 GO:0019207 kinase regulator activity
3.07 1.52e-02 GO:0030234 enzyme regulator activity