Motif ID: ZEB1.p2

Z-value: 3.028


Transcription factors associated with ZEB1.p2:

Gene SymbolEntrez IDGene Name
ZEB1 6935 zinc finger E-box binding homeobox 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
ZEB1chr10_+_31610063-0.829.7e-05Click!


Activity profile for motif ZEB1.p2.

activity profile for motif ZEB1.p2


Sorted Z-values histogram for motif ZEB1.p2

Sorted Z-values for motif ZEB1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZEB1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_+_38755422 10.527 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr19_+_38755238 9.980 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr19_+_38755097 9.796 NM_001166103
NM_021102
SPINT2

serine peptidase inhibitor, Kunitz type, 2

chr7_+_26331493 7.878 NM_001199835
NM_013322
SNX10

sorting nexin 10

chr4_+_75310852 7.654 NM_001657
AREG
amphiregulin
chr2_+_47596286 6.621 NM_002354
EPCAM
epithelial cell adhesion molecule
chr4_+_75480628 6.606 NM_001657
AREG
amphiregulin
chr18_+_29078026 6.598 NM_001943
DSG2
desmoglein 2
chr2_+_47596447 6.375 EPCAM
epithelial cell adhesion molecule
chr1_+_1981902 6.279 NM_002744
PRKCZ
protein kinase C, zeta
chr6_+_7541837 6.233 DSP
desmoplakin
chr6_+_7541863 6.087 NM_001008844
NM_004415
DSP

desmoplakin

chr6_+_7541892 5.984 DSP
desmoplakin
chr7_+_26331611 5.878 SNX10
sorting nexin 10
chr20_-_6103562 5.842 FERMT1
fermitin family member 1
chr16_+_68771192 5.255 NM_004360
CDH1
cadherin 1, type 1, E-cadherin (epithelial)
chr21_-_43187197 5.027 NM_020639
RIPK4
receptor-interacting serine-threonine kinase 4
chr1_+_60280462 4.857 NM_015888
HOOK1
hook homolog 1 (Drosophila)
chr2_-_166650770 4.798 NM_004482
GALNT3
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)
chr19_+_35739519 4.771 NM_015925
NM_205834
NM_205835
LSR


lipolysis stimulated lipoprotein receptor



Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 10 of 10 entries
Enrichment   P-value GO Accession GO Term
13.32 2.52e-02 GO:0031100 organ regeneration
7.79 3.20e-05 GO:0008544 epidermis development
4.51 4.58e-03 GO:0060429 epithelium development
3.86 6.51e-04 GO:0009887 organ morphogenesis
3.18 1.67e-03 GO:0009888 tissue development
2.38 4.45e-04 GO:0048513 organ development
2.00 1.35e-03 GO:0048731 system development
1.97 5.59e-04 GO:0048856 anatomical structure development
1.80 9.95e-03 GO:0007275 multicellular organismal development
1.74 1.21e-02 GO:0032502 developmental process

Gene overrepresentation in compartment category:

Showing 1 to 11 of 11 entries
Enrichment   P-value GO Accession GO Term
28.11 1.03e-04 GO:0030057 desmosome
6.37 5.84e-04 GO:0005911 cell-cell junction
5.51 1.58e-02 GO:0070161 anchoring junction
4.94 5.41e-03 GO:0016323 basolateral plasma membrane
3.14 2.31e-02 GO:0030054 cell junction
2.32 1.47e-05 GO:0044459 plasma membrane part
1.94 1.11e-05 GO:0005886 plasma membrane
1.91 1.90e-05 GO:0071944 cell periphery
1.57 1.47e-03 GO:0044425 membrane part
1.55 3.76e-05 GO:0016020 membrane
1.32 2.33e-02 GO:0005737 cytoplasm

Nothing significant found in function category.