Motif ID: bHLH_family.p2

Z-value: 1.992


Transcription factors associated with bHLH_family.p2:

Gene SymbolEntrez IDGene Name
ARNTL 406 aryl hydrocarbon receptor nuclear translocator-like
ARNTL2 56938 aryl hydrocarbon receptor nuclear translocator-like 2
CLOCK 9575 clock homolog (mouse)
HES6 55502 hairy and enhancer of split 6 (Drosophila)
HEY1 23462 hairy/enhancer-of-split related with YRPW motif 1
HEY2 23493 hairy/enhancer-of-split related with YRPW motif 2
HEYL 26508 hairy/enhancer-of-split related with YRPW motif-like
ID1 3397 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
MITF 4286 microphthalmia-associated transcription factor
MLXIPL 51085 MLX interacting protein-like
MNT 4335 MAX binding protein
MXD3 83463 MAX dimerization protein 3
MXD4 10608 MAX dimerization protein 4
MXI1 4601 MAX interactor 1
NPAS2 4862 neuronal PAS domain protein 2
OLIG1 116448 oligodendrocyte transcription factor 1
OLIG2 10215 oligodendrocyte lineage transcription factor 2
TFE3 7030 transcription factor binding to IGHM enhancer 3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
MLXIPLchr7_-_730388140.621.0e-02Click!
MXD4chr4_-_2263706-0.611.2e-02Click!
TFE3chrX_-_48900932-0.581.9e-02Click!
NPAS2chr2_+_1014364910.448.6e-02Click!
MITFchr3_+_69812961-0.439.7e-02Click!
HEY1chr8_-_806798970.421.1e-01Click!
ID1chr20_+_301930830.381.5e-01Click!
OLIG2chr21_+_34398210-0.351.9e-01Click!
ARNTLchr11_+_13299260-0.243.8e-01Click!
MXI1chr10_+_111969988,
chr10_+_111985628		0.233.8e-01Click!
HEY2chr6_+_126070724,
chr6_+_126070813		0.204.5e-01Click!
ARNTL2chr12_+_27485767-0.185.0e-01Click!
HEYLchr1_-_40105341,
chr1_-_40098639,
chr1_-_40105296		0.126.7e-01Click!
MXD3chr5_-_176738831-0.087.6e-01Click!
MNTchr17_-_23042170.048.7e-01Click!
CLOCKchr4_-_56412968-0.029.5e-01Click!


Activity profile for motif bHLH_family.p2.

activity profile for motif bHLH_family.p2


Sorted Z-values histogram for motif bHLH_family.p2

Sorted Z-values for motif bHLH_family.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of bHLH_family.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_+_10765106 3.556 ILF3
interleukin enhancer binding factor 3, 90kDa
chrX_+_152908819 3.428 DUSP9
dual specificity phosphatase 9
chrX_+_131157635 3.217 NM_001042452
 MST4
serine/threonine protein kinase MST4
chr14_-_55369163 3.152 NM_000161
NM_001024024
NM_001024070
NM_001024071
 GCH1



GTP cyclohydrolase 1



chr19_+_18284578 3.106 NM_006332
 IFI30
interferon, gamma-inducible protein 30
chr1_-_113498615 3.046 NM_001166496
 SLC16A1
solute carrier family 16, member 1 (monocarboxylic acid transporter 1)
chr1_-_161193375 3.045 NM_001643
 APOA2
apolipoprotein A-II
chr11_+_121322848 2.801 NM_003105
 SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr6_+_87865261 2.757 NM_015021
 ZNF292
zinc finger protein 292
chr12_-_63328857 2.684 PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr14_-_94849552 2.624 SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr17_+_76164624 2.614 NM_004710
 SYNGR2
synaptogyrin 2
chr19_-_10764449 2.612 LOC147727
uncharacterized LOC147727
chr17_+_55163077 2.592 NM_001242903
NM_001242902
 AKAP1

A kinase (PRKA) anchor protein 1

chrX_-_133119475 2.543 GPC3
glypican 3
chrX_+_131157231 2.542 NM_001042453
NM_016542
 MST4

serine/threonine protein kinase MST4

chrX_-_133119624 2.423 NM_001164617
NM_001164618
NM_001164619
NM_004484
 GPC3



glypican 3



chr2_-_208634051 2.418 NM_003468
 FZD5
frizzled family receptor 5
chr20_+_61273823 2.414 SLCO4A1
solute carrier organic anion transporter family, member 4A1
chr11_+_68079999 2.404 NM_002335
 LRP5
low density lipoprotein receptor-related protein 5

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.