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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for AR_NR3C2

Z-value: 0.43

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Transcription factors associated with AR_NR3C2

Gene Symbol Gene ID Gene Info
AR
ENSG00000169083.11 androgen receptor
NR3C2
ENSG00000151623.10 nuclear receptor subfamily 3 group C member 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ARhg19_v2_chrX_+_66764375_667644650.955.0e-02Click!
NR3C2hg19_v2_chr4_-_149365827_149365870-0.811.9e-01Click!

Activity profile of AR_NR3C2 motif

Sorted Z-values of AR_NR3C2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_122241812 0.30 ENST00000538335.1
AC084018.1
AC084018.1
chr9_-_106087316 0.28 ENST00000411575.1
RP11-341A22.2
RP11-341A22.2
chr7_-_75241096 0.26 ENST00000420909.1
HIP1
huntingtin interacting protein 1
chr16_-_787771 0.23 ENST00000568545.1
NARFL
nuclear prelamin A recognition factor-like
chr5_+_140186647 0.19 ENST00000512229.2
ENST00000356878.4
ENST00000530339.1
PCDHA4
protocadherin alpha 4
chr11_+_18287801 0.17 ENST00000532858.1
ENST00000405158.2
SAA1
serum amyloid A1
chr19_-_8408139 0.17 ENST00000330915.3
ENST00000593649.1
ENST00000595639.1
KANK3
KN motif and ankyrin repeat domains 3
chr12_+_53443680 0.16 ENST00000314250.6
ENST00000451358.1
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr5_-_141392538 0.16 ENST00000503794.1
ENST00000510194.1
ENST00000504424.1
ENST00000513454.1
ENST00000458112.2
ENST00000542860.1
ENST00000503229.1
ENST00000500692.2
ENST00000311337.6
ENST00000504139.1
ENST00000505689.1
GNPDA1
glucosamine-6-phosphate deaminase 1
chr11_-_236326 0.15 ENST00000525237.1
ENST00000532956.1
ENST00000525319.1
ENST00000524564.1
ENST00000382743.4
SIRT3
sirtuin 3
chr17_+_79071365 0.15 ENST00000576756.1
BAIAP2
BAI1-associated protein 2
chr17_-_14140166 0.15 ENST00000420162.2
ENST00000431716.2
CDRT15
CMT1A duplicated region transcript 15
chr6_-_26235206 0.14 ENST00000244534.5
HIST1H1D
histone cluster 1, H1d
chr12_+_52203789 0.13 ENST00000599343.1
AC068987.1
HCG1997999; cDNA FLJ33996 fis, clone DFNES2008881
chr16_-_4852915 0.13 ENST00000322048.7
ROGDI
rogdi homolog (Drosophila)
chr4_-_76598052 0.12 ENST00000509100.1
G3BP2
GTPase activating protein (SH3 domain) binding protein 2
chr12_+_53443963 0.12 ENST00000546602.1
ENST00000552570.1
ENST00000549700.1
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr19_+_56187987 0.11 ENST00000411543.2
EPN1
epsin 1
chr8_-_72756667 0.11 ENST00000325509.4
MSC
musculin
chr19_+_35630628 0.10 ENST00000588715.1
ENST00000588607.1
FXYD1
FXYD domain containing ion transport regulator 1
chr8_+_38614754 0.09 ENST00000521642.1
TACC1
transforming, acidic coiled-coil containing protein 1
chr2_+_238395879 0.09 ENST00000445024.2
ENST00000338530.4
ENST00000409373.1
MLPH
melanophilin
chr16_+_67207838 0.09 ENST00000566871.1
ENST00000268605.7
NOL3
nucleolar protein 3 (apoptosis repressor with CARD domain)
chr4_+_8442496 0.09 ENST00000389737.4
ENST00000504134.1
TRMT44
tRNA methyltransferase 44 homolog (S. cerevisiae)
chrX_-_80377118 0.09 ENST00000373250.3
HMGN5
high mobility group nucleosome binding domain 5
chr11_+_18287721 0.09 ENST00000356524.4
SAA1
serum amyloid A1
chr19_+_54704610 0.08 ENST00000302907.4
RPS9
ribosomal protein S9
chr3_-_134093738 0.08 ENST00000506107.1
AMOTL2
angiomotin like 2
chr19_-_42916499 0.08 ENST00000601189.1
ENST00000599211.1
LIPE
lipase, hormone-sensitive
chr3_+_13521665 0.08 ENST00000295757.3
ENST00000402259.1
ENST00000402271.1
ENST00000446613.2
ENST00000404548.1
ENST00000404040.1
HDAC11
histone deacetylase 11
chrX_-_80377162 0.08 ENST00000430960.1
ENST00000447319.1
HMGN5
high mobility group nucleosome binding domain 5
chr19_+_1261106 0.08 ENST00000588411.1
CIRBP
cold inducible RNA binding protein
chr5_-_149792295 0.08 ENST00000518797.1
ENST00000524315.1
ENST00000009530.7
ENST00000377795.3
CD74
CD74 molecule, major histocompatibility complex, class II invariant chain
chr2_+_238395803 0.08 ENST00000264605.3
MLPH
melanophilin
chr2_-_242576864 0.08 ENST00000407315.1
THAP4
THAP domain containing 4
chr10_+_696000 0.08 ENST00000381489.5
PRR26
proline rich 26
chr16_-_66584059 0.07 ENST00000417693.3
ENST00000544898.1
ENST00000569718.1
ENST00000527284.1
ENST00000299697.7
ENST00000451102.2
TK2
thymidine kinase 2, mitochondrial
chr16_-_4852616 0.07 ENST00000591392.1
ENST00000587711.1
ROGDI
rogdi homolog (Drosophila)
chr11_-_506739 0.07 ENST00000529306.1
ENST00000438658.2
ENST00000527485.1
ENST00000397615.2
ENST00000397614.1
RNH1
ribonuclease/angiogenin inhibitor 1
chr12_+_51318513 0.06 ENST00000332160.4
METTL7A
methyltransferase like 7A
chr10_-_375422 0.06 ENST00000434695.2
DIP2C
DIP2 disco-interacting protein 2 homolog C (Drosophila)
chr2_-_27435390 0.06 ENST00000428518.1
SLC5A6
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
chr8_+_38614778 0.06 ENST00000521050.1
ENST00000522904.1
TACC1
transforming, acidic coiled-coil containing protein 1
chr11_-_114271139 0.06 ENST00000325636.4
C11orf71
chromosome 11 open reading frame 71
chr2_+_102953608 0.06 ENST00000311734.2
ENST00000409584.1
IL1RL1
interleukin 1 receptor-like 1
chr17_-_79304150 0.06 ENST00000574093.1
TMEM105
transmembrane protein 105
chr17_-_3794021 0.05 ENST00000381769.2
CAMKK1
calcium/calmodulin-dependent protein kinase kinase 1, alpha
chr12_-_53575120 0.05 ENST00000542115.1
CSAD
cysteine sulfinic acid decarboxylase
chr1_-_49242553 0.05 ENST00000371833.3
BEND5
BEN domain containing 5
chr2_-_27435634 0.05 ENST00000430186.1
SLC5A6
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
chr1_-_27693349 0.05 ENST00000374040.3
ENST00000357582.2
ENST00000493901.1
MAP3K6
mitogen-activated protein kinase kinase kinase 6
chr22_+_38054721 0.05 ENST00000215904.6
PDXP
pyridoxal (pyridoxine, vitamin B6) phosphatase
chr22_+_24030321 0.05 ENST00000401461.1
RGL4
ral guanine nucleotide dissociation stimulator-like 4
chr2_-_73298802 0.04 ENST00000411783.1
ENST00000410065.1
ENST00000442582.1
ENST00000272433.2
SFXN5
sideroflexin 5
chr10_+_48359344 0.04 ENST00000412534.1
ENST00000444585.1
ZNF488
zinc finger protein 488
chr2_-_109605663 0.04 ENST00000409271.1
ENST00000258443.2
ENST00000376651.1
EDAR
ectodysplasin A receptor
chr16_+_67207872 0.04 ENST00000563258.1
ENST00000568146.1
NOL3
nucleolar protein 3 (apoptosis repressor with CARD domain)
chr1_-_10856694 0.04 ENST00000377022.3
ENST00000344008.5
CASZ1
castor zinc finger 1
chr13_+_114462193 0.04 ENST00000375353.3
TMEM255B
transmembrane protein 255B
chr17_-_19290117 0.04 ENST00000497081.2
MFAP4
microfibrillar-associated protein 4
chr16_+_56672571 0.04 ENST00000290705.8
MT1A
metallothionein 1A
chr16_+_56642041 0.04 ENST00000245185.5
MT2A
metallothionein 2A
chr13_-_26452679 0.04 ENST00000596729.1
AL138815.2
Uncharacterized protein
chr2_-_231825668 0.04 ENST00000392039.2
GPR55
G protein-coupled receptor 55
chr7_-_4877677 0.04 ENST00000538469.1
RADIL
Ras association and DIL domains
chr2_+_27435179 0.04 ENST00000606999.1
ENST00000405489.3
ATRAID
all-trans retinoic acid-induced differentiation factor
chr17_-_16472483 0.04 ENST00000395824.1
ENST00000448349.2
ENST00000395825.3
ZNF287
zinc finger protein 287
chr5_-_60139347 0.03 ENST00000511799.1
ELOVL7
ELOVL fatty acid elongase 7
chr2_+_242577027 0.03 ENST00000402096.1
ENST00000404914.3
ATG4B
autophagy related 4B, cysteine peptidase
chr12_+_122241928 0.03 ENST00000604567.1
ENST00000542440.1
SETD1B
SET domain containing 1B
chr12_-_56615693 0.03 ENST00000394013.2
ENST00000345093.4
ENST00000551711.1
ENST00000552656.1
RNF41
ring finger protein 41
chr11_-_75380165 0.03 ENST00000304771.3
MAP6
microtubule-associated protein 6
chr2_-_75788424 0.03 ENST00000410071.1
EVA1A
eva-1 homolog A (C. elegans)
chr6_+_31638156 0.03 ENST00000409525.1
LY6G5B
lymphocyte antigen 6 complex, locus G5B
chr14_-_24616426 0.03 ENST00000216802.5
PSME2
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr12_-_56848426 0.03 ENST00000257979.4
MIP
major intrinsic protein of lens fiber
chr19_+_57874835 0.02 ENST00000543226.1
ENST00000596755.1
ENST00000282282.3
ENST00000597658.1
TRAPPC2P1
ZNF547
AC003002.4
trafficking protein particle complex 2 pseudogene 1
zinc finger protein 547
Uncharacterized protein
chr3_+_52279737 0.02 ENST00000457351.2
PPM1M
protein phosphatase, Mg2+/Mn2+ dependent, 1M
chr8_-_145634731 0.02 ENST00000349769.3
CPSF1
cleavage and polyadenylation specific factor 1, 160kDa
chr15_+_65204075 0.02 ENST00000380230.3
ENST00000357698.3
ENST00000395720.1
ENST00000496660.1
ENST00000319580.8
ANKDD1A
ankyrin repeat and death domain containing 1A
chr22_+_18632666 0.02 ENST00000215794.7
USP18
ubiquitin specific peptidase 18
chr11_+_48002076 0.02 ENST00000418331.2
ENST00000440289.2
PTPRJ
protein tyrosine phosphatase, receptor type, J
chr2_+_27435734 0.02 ENST00000419744.1
ATRAID
all-trans retinoic acid-induced differentiation factor
chr4_-_69215699 0.02 ENST00000510746.1
ENST00000344157.4
ENST00000355665.3
YTHDC1
YTH domain containing 1
chr19_-_14117074 0.02 ENST00000588885.1
ENST00000254325.4
RFX1
regulatory factor X, 1 (influences HLA class II expression)
chr10_+_115674530 0.02 ENST00000451472.1
AL162407.1
CDNA FLJ20147 fis, clone COL07954; HCG1781466; Uncharacterized protein
chr8_-_110615669 0.02 ENST00000533394.1
SYBU
syntabulin (syntaxin-interacting)
chr7_+_74379083 0.02 ENST00000361825.7
GATSL1
GATS protein-like 1
chr9_-_35563896 0.01 ENST00000399742.2
FAM166B
family with sequence similarity 166, member B
chr8_+_91013577 0.01 ENST00000220764.2
DECR1
2,4-dienoyl CoA reductase 1, mitochondrial
chr9_+_131683174 0.01 ENST00000372592.3
ENST00000428610.1
PHYHD1
phytanoyl-CoA dioxygenase domain containing 1
chr11_-_5959840 0.01 ENST00000412903.1
TRIM5
tripartite motif containing 5
chr12_+_125549925 0.01 ENST00000316519.6
AACS
acetoacetyl-CoA synthetase
chr6_+_123317116 0.01 ENST00000275162.5
CLVS2
clavesin 2
chr17_+_38498594 0.01 ENST00000394081.3
RARA
retinoic acid receptor, alpha
chr8_+_9046503 0.01 ENST00000512942.2
RP11-10A14.5
RP11-10A14.5
chr20_+_15177480 0.01 ENST00000402914.1
MACROD2
MACRO domain containing 2
chr12_+_125549973 0.01 ENST00000536752.1
ENST00000261686.6
AACS
acetoacetyl-CoA synthetase
chr9_-_40792063 0.01 ENST00000377626.3
ENST00000441795.1
ENST00000602553.1
ZNF658
zinc finger protein 658
chr19_-_45657028 0.01 ENST00000429338.1
ENST00000589776.1
NKPD1
NTPase, KAP family P-loop domain containing 1
chrX_+_2609207 0.01 ENST00000381192.3
CD99
CD99 molecule
chr5_-_173043591 0.01 ENST00000285908.5
ENST00000480951.1
ENST00000311086.4
BOD1
biorientation of chromosomes in cell division 1
chr8_+_38614807 0.01 ENST00000330691.6
ENST00000348567.4
TACC1
transforming, acidic coiled-coil containing protein 1
chr16_-_787728 0.01 ENST00000567403.1
ENST00000562421.1
NARFL
nuclear prelamin A recognition factor-like
chr17_-_65242063 0.01 ENST00000581159.1
HELZ
helicase with zinc finger
chr2_+_242577097 0.01 ENST00000419606.1
ENST00000474739.2
ENST00000396411.3
ENST00000425239.1
ENST00000400771.3
ENST00000430617.2
ATG4B
autophagy related 4B, cysteine peptidase
chr12_-_56615485 0.01 ENST00000549038.1
ENST00000552244.1
RNF41
ring finger protein 41
chr1_+_93811438 0.01 ENST00000370272.4
ENST00000370267.1
DR1
down-regulator of transcription 1, TBP-binding (negative cofactor 2)
chr2_-_37551846 0.01 ENST00000443187.1
PRKD3
protein kinase D3
chr4_+_87928140 0.01 ENST00000307808.6
AFF1
AF4/FMR2 family, member 1
chr17_-_19290483 0.00 ENST00000395592.2
ENST00000299610.4
MFAP4
microfibrillar-associated protein 4
chr17_+_41323204 0.00 ENST00000542611.1
ENST00000590996.1
ENST00000389312.4
ENST00000589872.1
NBR1
neighbor of BRCA1 gene 1
chr4_-_69817481 0.00 ENST00000251566.4
UGT2A3
UDP glucuronosyltransferase 2 family, polypeptide A3
chr12_+_1099675 0.00 ENST00000545318.2
ERC1
ELKS/RAB6-interacting/CAST family member 1
chr8_-_21669826 0.00 ENST00000517328.1
GFRA2
GDNF family receptor alpha 2
chr1_+_61547405 0.00 ENST00000371189.4
NFIA
nuclear factor I/A
chrX_-_117119243 0.00 ENST00000539496.1
ENST00000469946.1
KLHL13
kelch-like family member 13

Network of associatons between targets according to the STRING database.

First level regulatory network of AR_NR3C2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:2000588 positive regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000588)
0.1 0.2 GO:0006043 glucosamine catabolic process(GO:0006043)
0.0 0.1 GO:0014876 response to injury involved in regulation of muscle adaptation(GO:0014876)
0.0 0.1 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.0 0.1 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 0.1 GO:0015887 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887)
0.0 0.2 GO:0032364 oxygen homeostasis(GO:0032364)
0.0 0.0 GO:0031247 actin rod assembly(GO:0031247)
0.0 0.1 GO:0002905 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.0 0.1 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.1 GO:0046092 deoxycytidine metabolic process(GO:0046092)
0.0 0.1 GO:1905232 cellular response to L-glutamate(GO:1905232)
0.0 0.1 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.0 0.2 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 0.1 GO:0042412 taurine biosynthetic process(GO:0042412)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0097361 CIA complex(GO:0097361)
0.0 0.3 GO:0071682 endocytic vesicle lumen(GO:0071682)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.0 0.1 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.0 0.3 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.1 GO:0002113 interleukin-33 binding(GO:0002113)
0.0 0.1 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.0 0.1 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 0.0 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.0 0.1 GO:0035877 death effector domain binding(GO:0035877)
0.0 0.1 GO:0004137 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.0 0.1 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.1 GO:0004782 sulfinoalanine decarboxylase activity(GO:0004782)
0.0 0.1 GO:1990932 5.8S rRNA binding(GO:1990932)