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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for CREB5_CREM_JUNB

Z-value: 0.93

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Transcription factors associated with CREB5_CREM_JUNB

Gene Symbol Gene ID Gene Info
CREB5
ENSG00000146592.12 cAMP responsive element binding protein 5
CREM
ENSG00000095794.15 cAMP responsive element modulator
JUNB
ENSG00000171223.4 JunB proto-oncogene, AP-1 transcription factor subunit

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
JUNBhg19_v2_chr19_+_12902289_12902310-0.995.1e-03Click!
CREB5hg19_v2_chr7_+_28725585_28725608-0.928.0e-02Click!
CREMhg19_v2_chr10_+_35456444_354564980.918.9e-02Click!

Activity profile of CREB5_CREM_JUNB motif

Sorted Z-values of CREB5_CREM_JUNB motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chrX_-_135056106 0.75 ENST00000433339.2
MMGT1
membrane magnesium transporter 1
chr22_-_44258280 0.70 ENST00000540422.1
SULT4A1
sulfotransferase family 4A, member 1
chr8_+_26149274 0.63 ENST00000522535.1
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr19_-_10341948 0.61 ENST00000590320.1
ENST00000592342.1
ENST00000588952.1
S1PR2
DNMT1
sphingosine-1-phosphate receptor 2
DNA (cytosine-5-)-methyltransferase 1
chr2_+_37571845 0.57 ENST00000537448.1
QPCT
glutaminyl-peptide cyclotransferase
chr7_-_140624499 0.56 ENST00000288602.6
BRAF
v-raf murine sarcoma viral oncogene homolog B
chr18_+_77867177 0.56 ENST00000560752.1
ADNP2
ADNP homeobox 2
chr10_+_35484053 0.54 ENST00000487763.1
ENST00000473940.1
ENST00000488328.1
ENST00000356917.5
CREM
cAMP responsive element modulator
chr1_+_156030937 0.54 ENST00000361084.5
RAB25
RAB25, member RAS oncogene family
chr4_-_104119528 0.50 ENST00000380026.3
ENST00000503705.1
ENST00000265148.3
CENPE
centromere protein E, 312kDa
chr6_-_70506963 0.50 ENST00000370577.3
LMBRD1
LMBR1 domain containing 1
chr1_+_168148169 0.48 ENST00000367833.2
TIPRL
TIP41, TOR signaling pathway regulator-like (S. cerevisiae)
chr3_+_170075436 0.47 ENST00000476188.1
ENST00000259119.4
ENST00000426052.2
SKIL
SKI-like oncogene
chr6_-_27440460 0.45 ENST00000377419.1
ZNF184
zinc finger protein 184
chr4_-_104119488 0.45 ENST00000514974.1
CENPE
centromere protein E, 312kDa
chrX_-_135056216 0.44 ENST00000305963.2
MMGT1
membrane magnesium transporter 1
chr2_-_151395525 0.43 ENST00000439275.1
RND3
Rho family GTPase 3
chr6_+_56819773 0.42 ENST00000370750.2
BEND6
BEN domain containing 6
chr8_-_94928861 0.41 ENST00000607097.1
MIR378D2
microRNA 378d-2
chr1_+_168148273 0.41 ENST00000367830.3
TIPRL
TIP41, TOR signaling pathway regulator-like (S. cerevisiae)
chr2_+_3705785 0.41 ENST00000252505.3
ALLC
allantoicase
chr10_+_119000604 0.40 ENST00000298472.5
SLC18A2
solute carrier family 18 (vesicular monoamine transporter), member 2
chr6_-_27440837 0.40 ENST00000211936.6
ZNF184
zinc finger protein 184
chr14_-_103989033 0.40 ENST00000553878.1
ENST00000557530.1
CKB
creatine kinase, brain
chr6_-_19804973 0.39 ENST00000457670.1
ENST00000607810.1
ENST00000606628.1
RP4-625H18.2
RP4-625H18.2
chr17_+_29421987 0.38 ENST00000431387.4
NF1
neurofibromin 1
chr12_+_100661156 0.37 ENST00000360820.2
SCYL2
SCY1-like 2 (S. cerevisiae)
chr2_+_37571717 0.36 ENST00000338415.3
ENST00000404976.1
QPCT
glutaminyl-peptide cyclotransferase
chr8_+_26149007 0.35 ENST00000380737.3
ENST00000524169.1
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr14_+_60716159 0.35 ENST00000325658.3
PPM1A
protein phosphatase, Mg2+/Mn2+ dependent, 1A
chrX_-_47863348 0.35 ENST00000376943.3
ENST00000396965.1
ENST00000305127.6
ZNF182
zinc finger protein 182
chr19_+_8455200 0.35 ENST00000601897.1
ENST00000594216.1
RAB11B
RAB11B, member RAS oncogene family
chr3_+_158288999 0.34 ENST00000482628.1
ENST00000478894.2
ENST00000392822.3
ENST00000466246.1
MLF1
myeloid leukemia factor 1
chr18_+_23806437 0.34 ENST00000578121.1
TAF4B
TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
chr12_+_69004805 0.34 ENST00000541216.1
RAP1B
RAP1B, member of RAS oncogene family
chr14_+_68086515 0.34 ENST00000261783.3
ARG2
arginase 2
chr6_-_30523865 0.33 ENST00000433809.1
GNL1
guanine nucleotide binding protein-like 1
chr4_+_1873155 0.33 ENST00000507820.1
ENST00000514045.1
WHSC1
Wolf-Hirschhorn syndrome candidate 1
chr12_+_100660909 0.32 ENST00000549687.1
SCYL2
SCY1-like 2 (S. cerevisiae)
chr21_-_43430440 0.32 ENST00000398505.3
ENST00000310826.5
ENST00000449949.1
ENST00000398499.1
ENST00000398497.2
ENST00000398511.3
ZBTB21
zinc finger and BTB domain containing 21
chr20_+_55099542 0.32 ENST00000371328.3
FAM209A
family with sequence similarity 209, member A
chr7_-_124569864 0.32 ENST00000609702.1
POT1
protection of telomeres 1
chr2_+_70142189 0.32 ENST00000264444.2
MXD1
MAX dimerization protein 1
chr1_+_85527987 0.32 ENST00000326813.8
ENST00000294664.6
ENST00000528899.1
WDR63
WD repeat domain 63
chr3_+_159570722 0.31 ENST00000482804.1
SCHIP1
schwannomin interacting protein 1
chr3_+_63898275 0.31 ENST00000538065.1
ATXN7
ataxin 7
chr3_+_156544057 0.31 ENST00000498839.1
ENST00000470811.1
ENST00000356539.4
ENST00000483177.1
ENST00000477399.1
ENST00000491763.1
LEKR1
leucine, glutamate and lysine rich 1
chr20_+_5892147 0.31 ENST00000455042.1
CHGB
chromogranin B (secretogranin 1)
chr10_-_31320840 0.31 ENST00000375311.1
ZNF438
zinc finger protein 438
chr4_-_76598326 0.31 ENST00000503660.1
G3BP2
GTPase activating protein (SH3 domain) binding protein 2
chr1_+_70820451 0.31 ENST00000361764.4
ENST00000359875.5
ENST00000370940.5
ENST00000531950.1
ENST00000432224.1
HHLA3
HERV-H LTR-associating 3
chr5_+_172332220 0.30 ENST00000518247.1
ENST00000326654.2
ERGIC1
endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1
chr4_-_156298028 0.30 ENST00000433024.1
ENST00000379248.2
MAP9
microtubule-associated protein 9
chr10_-_31320860 0.30 ENST00000436087.2
ENST00000442986.1
ENST00000413025.1
ENST00000452305.1
ZNF438
zinc finger protein 438
chr17_+_29421900 0.30 ENST00000358273.4
ENST00000356175.3
NF1
neurofibromin 1
chr5_-_132948216 0.30 ENST00000265342.7
FSTL4
follistatin-like 4
chr8_-_17104099 0.30 ENST00000524358.1
CNOT7
CCR4-NOT transcription complex, subunit 7
chr8_+_38243967 0.30 ENST00000524874.1
ENST00000379957.4
ENST00000523983.2
LETM2
leucine zipper-EF-hand containing transmembrane protein 2
chr15_-_66790146 0.30 ENST00000316634.5
SNAPC5
small nuclear RNA activating complex, polypeptide 5, 19kDa
chr17_+_33914424 0.29 ENST00000590432.1
AP2B1
adaptor-related protein complex 2, beta 1 subunit
chr6_-_106773291 0.29 ENST00000343245.3
ATG5
autophagy related 5
chr11_+_18343800 0.29 ENST00000453096.2
GTF2H1
general transcription factor IIH, polypeptide 1, 62kDa
chr17_+_66509019 0.29 ENST00000585981.1
ENST00000589480.1
ENST00000585815.1
PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr12_+_69004736 0.29 ENST00000545720.2
RAP1B
RAP1B, member of RAS oncogene family
chr4_-_668108 0.29 ENST00000304312.4
ATP5I
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E
chr19_+_1954632 0.28 ENST00000589350.1
CSNK1G2
casein kinase 1, gamma 2
chr11_-_82782861 0.28 ENST00000524635.1
ENST00000526205.1
ENST00000527633.1
ENST00000533486.1
ENST00000533276.2
RAB30
RAB30, member RAS oncogene family
chr1_+_109289279 0.28 ENST00000370008.3
STXBP3
syntaxin binding protein 3
chr2_+_149632783 0.28 ENST00000435030.1
KIF5C
kinesin family member 5C
chr4_-_156298087 0.28 ENST00000311277.4
MAP9
microtubule-associated protein 9
chr9_-_125027079 0.28 ENST00000417201.3
RBM18
RNA binding motif protein 18
chr4_-_156297919 0.28 ENST00000450097.1
MAP9
microtubule-associated protein 9
chr2_-_202645835 0.27 ENST00000264276.6
ALS2
amyotrophic lateral sclerosis 2 (juvenile)
chr12_+_100660940 0.27 ENST00000548392.1
SCYL2
SCY1-like 2 (S. cerevisiae)
chr9_+_111696664 0.27 ENST00000374624.3
ENST00000445175.1
FAM206A
family with sequence similarity 206, member A
chrX_+_155110956 0.27 ENST00000286448.6
ENST00000262640.6
ENST00000460621.1
VAMP7
vesicle-associated membrane protein 7
chr1_-_17380630 0.26 ENST00000375499.3
SDHB
succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
chr8_+_38243721 0.26 ENST00000527334.1
LETM2
leucine zipper-EF-hand containing transmembrane protein 2
chr9_+_134165195 0.26 ENST00000372261.1
PPAPDC3
phosphatidic acid phosphatase type 2 domain containing 3
chr14_-_50053081 0.26 ENST00000396020.3
ENST00000245458.6
RPS29
ribosomal protein S29
chr12_+_69004705 0.26 ENST00000534899.1
ENST00000453560.2
ENST00000378985.3
ENST00000540209.1
ENST00000540781.1
ENST00000535492.1
ENST00000539091.1
ENST00000542145.1
ENST00000485252.2
ENST00000541386.1
ENST00000538877.1
ENST00000543697.1
RAP1B
RAP1B, member of RAS oncogene family
chr19_+_2841433 0.26 ENST00000334241.4
ENST00000585966.1
ENST00000591539.1
ZNF555
zinc finger protein 555
chr21_+_17443521 0.26 ENST00000456342.1
LINC00478
long intergenic non-protein coding RNA 478
chr10_+_124739964 0.26 ENST00000406217.2
PSTK
phosphoseryl-tRNA kinase
chr6_-_86353510 0.26 ENST00000444272.1
SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chr15_-_34394008 0.26 ENST00000527822.1
ENST00000528949.1
EMC7
ER membrane protein complex subunit 7
chr1_+_22379179 0.26 ENST00000315554.8
ENST00000421089.2
CDC42
cell division cycle 42
chr14_+_102276209 0.25 ENST00000445439.3
ENST00000334743.5
ENST00000557095.1
PPP2R5C
protein phosphatase 2, regulatory subunit B', gamma
chr4_+_75311019 0.25 ENST00000502307.1
AREG
amphiregulin
chr20_+_55108302 0.25 ENST00000371325.1
FAM209B
family with sequence similarity 209, member B
chr5_+_112849373 0.25 ENST00000161863.4
ENST00000515883.1
YTHDC2
YTH domain containing 2
chr5_+_68513622 0.25 ENST00000512880.1
ENST00000602380.1
MRPS36
mitochondrial ribosomal protein S36
chr1_+_27719148 0.25 ENST00000374024.3
GPR3
G protein-coupled receptor 3
chr16_-_3767506 0.25 ENST00000538171.1
TRAP1
TNF receptor-associated protein 1
chr19_+_55795493 0.25 ENST00000309383.1
BRSK1
BR serine/threonine kinase 1
chr6_+_28048753 0.25 ENST00000377325.1
ZNF165
zinc finger protein 165
chr20_+_10199566 0.25 ENST00000430336.1
SNAP25
synaptosomal-associated protein, 25kDa
chr18_+_76829441 0.25 ENST00000458297.2
ATP9B
ATPase, class II, type 9B
chr7_+_23221438 0.24 ENST00000258742.5
NUPL2
nucleoporin like 2
chr18_+_268148 0.24 ENST00000581677.1
RP11-705O1.8
RP11-705O1.8
chr5_-_175965008 0.24 ENST00000537487.1
RNF44
ring finger protein 44
chr11_+_18344106 0.24 ENST00000534641.1
ENST00000525831.1
ENST00000265963.4
GTF2H1
general transcription factor IIH, polypeptide 1, 62kDa
chr1_+_28099700 0.24 ENST00000440806.2
STX12
syntaxin 12
chr3_+_158288960 0.24 ENST00000484955.1
ENST00000359117.5
ENST00000498592.1
ENST00000477042.1
ENST00000471745.1
ENST00000469452.1
MLF1
myeloid leukemia factor 1
chr7_+_120591170 0.24 ENST00000431467.1
ING3
inhibitor of growth family, member 3
chr16_+_4666475 0.24 ENST00000591895.1
MGRN1
mahogunin ring finger 1, E3 ubiquitin protein ligase
chr16_+_11343475 0.24 ENST00000572173.1
RMI2
RecQ mediated genome instability 2
chr3_+_62304648 0.23 ENST00000462069.1
ENST00000232519.5
ENST00000465142.1
C3orf14
chromosome 3 open reading frame 14
chr13_+_111767582 0.23 ENST00000375741.2
ENST00000375739.2
ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr6_-_159065741 0.23 ENST00000367085.3
ENST00000367089.3
DYNLT1
dynein, light chain, Tctex-type 1
chr8_+_38243951 0.23 ENST00000297720.5
LETM2
leucine zipper-EF-hand containing transmembrane protein 2
chr8_+_94929273 0.23 ENST00000518573.1
PDP1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr6_+_47445467 0.23 ENST00000359314.5
CD2AP
CD2-associated protein
chr5_-_78809950 0.23 ENST00000334082.6
HOMER1
homer homolog 1 (Drosophila)
chr13_+_49822041 0.23 ENST00000538056.1
ENST00000251108.6
ENST00000444959.1
ENST00000429346.1
CDADC1
cytidine and dCMP deaminase domain containing 1
chr6_-_106773610 0.23 ENST00000369076.3
ENST00000369070.1
ATG5
autophagy related 5
chr19_+_45971246 0.23 ENST00000585836.1
ENST00000417353.2
ENST00000353609.3
ENST00000591858.1
ENST00000443841.2
ENST00000590335.1
FOSB
FBJ murine osteosarcoma viral oncogene homolog B
chr2_+_70142232 0.22 ENST00000540449.1
MXD1
MAX dimerization protein 1
chr8_+_133787586 0.22 ENST00000395379.1
ENST00000395386.2
ENST00000337920.4
PHF20L1
PHD finger protein 20-like 1
chr4_-_39367949 0.22 ENST00000503784.1
ENST00000349703.2
ENST00000381897.1
RFC1
replication factor C (activator 1) 1, 145kDa
chr19_-_39402798 0.22 ENST00000571838.1
CTC-360G5.1
coiled-coil glutamate-rich protein 2
chr1_+_25071848 0.22 ENST00000374379.4
CLIC4
chloride intracellular channel 4
chr19_-_39881777 0.22 ENST00000595564.1
ENST00000221265.3
PAF1
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
chr3_+_187871659 0.22 ENST00000416784.1
ENST00000430340.1
ENST00000414139.1
ENST00000454789.1
LPP
LIM domain containing preferred translocation partner in lipoma
chr9_+_70856899 0.22 ENST00000377342.5
ENST00000478048.1
CBWD3
COBW domain containing 3
chr10_+_14920843 0.22 ENST00000433779.1
ENST00000378325.3
ENST00000354919.6
ENST00000313519.5
ENST00000420416.1
SUV39H2
suppressor of variegation 3-9 homolog 2 (Drosophila)
chr3_+_158288942 0.22 ENST00000491767.1
ENST00000355893.5
MLF1
myeloid leukemia factor 1
chr20_+_44420617 0.22 ENST00000449078.1
ENST00000456939.1
DNTTIP1
deoxynucleotidyltransferase, terminal, interacting protein 1
chr4_+_85504075 0.22 ENST00000295887.5
CDS1
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
chr1_+_52082751 0.22 ENST00000447887.1
ENST00000435686.2
ENST00000428468.1
ENST00000453295.1
OSBPL9
oxysterol binding protein-like 9
chr12_+_69004619 0.22 ENST00000250559.9
ENST00000393436.5
ENST00000425247.2
ENST00000489473.2
ENST00000422358.2
ENST00000541167.1
ENST00000538283.1
ENST00000341355.5
ENST00000537460.1
ENST00000450214.2
ENST00000545270.1
ENST00000538980.1
ENST00000542018.1
ENST00000543393.1
RAP1B
RAP1B, member of RAS oncogene family
chr1_-_154164534 0.21 ENST00000271850.7
ENST00000368530.2
TPM3
tropomyosin 3
chr8_-_10697281 0.21 ENST00000524114.1
ENST00000553390.1
ENST00000554914.1
PINX1
SOX7
SOX7
PIN2/TERF1 interacting, telomerase inhibitor 1
SRY (sex determining region Y)-box 7
Transcription factor SOX-7; Uncharacterized protein; cDNA FLJ58508, highly similar to Transcription factor SOX-7
chr3_-_51937331 0.21 ENST00000310914.5
IQCF1
IQ motif containing F1
chr6_-_106773491 0.21 ENST00000360666.4
ATG5
autophagy related 5
chr1_-_145382434 0.21 ENST00000610154.1
RP11-458D21.1
RP11-458D21.1
chr5_-_99870890 0.21 ENST00000499025.1
CTD-2001C12.1
CTD-2001C12.1
chr6_-_3157760 0.20 ENST00000333628.3
TUBB2A
tubulin, beta 2A class IIa
chr1_+_9599540 0.20 ENST00000302692.6
SLC25A33
solute carrier family 25 (pyrimidine nucleotide carrier), member 33
chr2_+_114195268 0.20 ENST00000259199.4
ENST00000416503.2
ENST00000433343.2
CBWD2
COBW domain containing 2
chr11_-_77185094 0.20 ENST00000278568.4
ENST00000356341.3
PAK1
p21 protein (Cdc42/Rac)-activated kinase 1
chr4_-_83931862 0.20 ENST00000506560.1
ENST00000442461.2
ENST00000446851.2
ENST00000340417.3
LIN54
lin-54 homolog (C. elegans)
chr4_+_113558272 0.20 ENST00000509061.1
ENST00000508577.1
ENST00000513553.1
LARP7
La ribonucleoprotein domain family, member 7
chr6_+_30908747 0.20 ENST00000462446.1
ENST00000304311.2
DPCR1
diffuse panbronchiolitis critical region 1
chr19_+_8455077 0.20 ENST00000328024.6
RAB11B
RAB11B, member RAS oncogene family
chr16_+_58535372 0.20 ENST00000566656.1
ENST00000566618.1
NDRG4
NDRG family member 4
chr15_+_42841008 0.20 ENST00000260372.3
ENST00000568876.1
ENST00000568846.2
ENST00000562398.1
HAUS2
HAUS augmin-like complex, subunit 2
chr3_+_62304712 0.20 ENST00000494481.1
C3orf14
chromosome 3 open reading frame 14
chr10_+_124134201 0.20 ENST00000368990.3
ENST00000368988.1
ENST00000368989.2
ENST00000463663.2
PLEKHA1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr4_-_146019693 0.20 ENST00000514390.1
ANAPC10
anaphase promoting complex subunit 10
chr3_+_38206975 0.20 ENST00000446845.1
ENST00000311806.3
OXSR1
oxidative stress responsive 1
chr4_-_113558014 0.20 ENST00000503172.1
ENST00000505019.1
ENST00000309071.5
C4orf21
chromosome 4 open reading frame 21
chr3_-_156877997 0.20 ENST00000295926.3
CCNL1
cyclin L1
chr4_-_113558079 0.20 ENST00000445203.2
C4orf21
chromosome 4 open reading frame 21
chr1_+_28099683 0.19 ENST00000373943.4
STX12
syntaxin 12
chr4_+_1873100 0.19 ENST00000508803.1
WHSC1
Wolf-Hirschhorn syndrome candidate 1
chr4_+_170541678 0.19 ENST00000360642.3
ENST00000512813.1
CLCN3
chloride channel, voltage-sensitive 3
chr17_+_66508154 0.19 ENST00000358598.2
PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr12_+_112856690 0.19 ENST00000392597.1
ENST00000351677.2
PTPN11
protein tyrosine phosphatase, non-receptor type 11
chr12_-_6772249 0.19 ENST00000467678.1
ENST00000493873.1
ENST00000423703.2
ENST00000412586.2
ENST00000444704.2
ING4
inhibitor of growth family, member 4
chr7_+_30174668 0.19 ENST00000415604.1
C7orf41
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr5_+_56469843 0.19 ENST00000514387.2
GPBP1
GC-rich promoter binding protein 1
chr12_-_51566562 0.19 ENST00000548108.1
TFCP2
transcription factor CP2
chr14_+_35515582 0.19 ENST00000382406.3
FAM177A1
family with sequence similarity 177, member A1
chr19_+_16186903 0.18 ENST00000588507.1
TPM4
tropomyosin 4
chr5_-_178054105 0.18 ENST00000316308.4
CLK4
CDC-like kinase 4
chr11_-_95523500 0.18 ENST00000540054.1
FAM76B
family with sequence similarity 76, member B
chr6_+_27833034 0.18 ENST00000357320.2
HIST1H2AL
histone cluster 1, H2al
chr11_-_28129656 0.18 ENST00000263181.6
KIF18A
kinesin family member 18A
chr9_-_128003606 0.18 ENST00000324460.6
HSPA5
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
chr6_-_53213780 0.18 ENST00000304434.6
ENST00000370918.4
ELOVL5
ELOVL fatty acid elongase 5
chr8_-_17104356 0.18 ENST00000361272.4
ENST00000523917.1
CNOT7
CCR4-NOT transcription complex, subunit 7
chr19_-_50528392 0.18 ENST00000600137.1
ENST00000597215.1
VRK3
vaccinia related kinase 3
chr10_-_90967063 0.18 ENST00000371852.2
CH25H
cholesterol 25-hydroxylase
chr22_+_32340481 0.18 ENST00000397492.1
YWHAH
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
chr4_+_75310851 0.18 ENST00000395748.3
ENST00000264487.2
AREG
amphiregulin
chr3_-_119182523 0.18 ENST00000319172.5
TMEM39A
transmembrane protein 39A
chr15_-_72612470 0.18 ENST00000287202.5
CELF6
CUGBP, Elav-like family member 6
chr13_+_111767650 0.18 ENST00000449979.1
ENST00000370623.3
ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr19_+_54960790 0.18 ENST00000443957.1
LENG8
leukocyte receptor cluster (LRC) member 8
chr1_-_245026388 0.18 ENST00000440865.1
HNRNPU
heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
chr1_+_22379120 0.18 ENST00000400259.1
ENST00000344548.3
CDC42
cell division cycle 42
chr17_+_41177220 0.18 ENST00000587250.2
ENST00000544533.1
RND2
Rho family GTPase 2
chr9_-_69262509 0.18 ENST00000377449.1
ENST00000382399.4
ENST00000377439.1
ENST00000377441.1
ENST00000377457.5
CBWD6
COBW domain containing 6
chr22_-_41252962 0.18 ENST00000216218.3
ST13
suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)
chr1_-_86861936 0.18 ENST00000394733.2
ENST00000359242.3
ENST00000294678.2
ENST00000479890.1
ENST00000317336.7
ENST00000370567.1
ENST00000394731.1
ENST00000478286.2
ENST00000370566.3
ODF2L
outer dense fiber of sperm tails 2-like
chr20_+_33292507 0.18 ENST00000414082.1
TP53INP2
tumor protein p53 inducible nuclear protein 2
chr5_-_178054014 0.18 ENST00000520957.1
CLK4
CDC-like kinase 4
chr12_+_19389814 0.18 ENST00000536974.1
PLEKHA5
pleckstrin homology domain containing, family A member 5
chr12_-_64616019 0.18 ENST00000311915.8
ENST00000398055.3
ENST00000544871.1
C12orf66
chromosome 12 open reading frame 66
chr11_-_3818932 0.17 ENST00000324932.7
ENST00000359171.4
NUP98
nucleoporin 98kDa
chr4_-_122791583 0.17 ENST00000506636.1
ENST00000264499.4
BBS7
Bardet-Biedl syndrome 7
chr15_-_42840961 0.17 ENST00000563454.1
ENST00000397130.3
ENST00000570160.1
ENST00000323443.2
LRRC57
leucine rich repeat containing 57
chr16_+_22825475 0.17 ENST00000261374.3
HS3ST2
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr4_-_170533723 0.17 ENST00000510533.1
ENST00000439128.2
ENST00000511633.1
ENST00000512193.1
ENST00000507142.1
NEK1
NIMA-related kinase 1
chr13_+_111972980 0.17 ENST00000283547.1
TEX29
testis expressed 29
chr5_+_133706865 0.17 ENST00000265339.2
UBE2B
ubiquitin-conjugating enzyme E2B
chr5_+_56469939 0.17 ENST00000506184.2
GPBP1
GC-rich promoter binding protein 1
chr9_+_125027127 0.17 ENST00000441707.1
ENST00000373723.5
ENST00000373729.1
MRRF
mitochondrial ribosome recycling factor
chr8_-_112248400 0.17 ENST00000519506.1
ENST00000522778.1
RP11-946L20.4
RP11-946L20.4

Network of associatons between targets according to the STRING database.

First level regulatory network of CREB5_CREM_JUNB

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.2 0.7 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.2 1.4 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.2 0.5 GO:1990519 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.1 0.4 GO:0060382 regulation of DNA strand elongation(GO:0060382)
0.1 0.1 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.1 0.4 GO:0043605 cellular amide catabolic process(GO:0043605)
0.1 0.9 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.1 0.4 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) sequestering of neurotransmitter(GO:0042137)
0.1 0.1 GO:1902232 regulation of positive thymic T cell selection(GO:1902232)
0.1 1.0 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.1 0.3 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.1 0.6 GO:0039689 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.1 0.3 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.1 0.8 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.1 0.3 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
0.1 0.3 GO:1990108 protein linear deubiquitination(GO:1990108)
0.1 0.2 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.1 0.3 GO:0009386 translational attenuation(GO:0009386)
0.1 1.0 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.1 0.6 GO:0090116 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.1 0.7 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.1 1.2 GO:0015693 magnesium ion transport(GO:0015693)
0.1 0.3 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 0.5 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.1 0.4 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.1 0.2 GO:2000687 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.1 0.2 GO:0070121 pronephric nephron morphogenesis(GO:0039007) pronephric nephron tubule morphogenesis(GO:0039008) pronephric duct development(GO:0039022) pronephric duct morphogenesis(GO:0039023) Kupffer's vesicle development(GO:0070121)
0.1 0.3 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.1 0.3 GO:0044026 DNA hypermethylation(GO:0044026) hypermethylation of CpG island(GO:0044027)
0.1 0.2 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.1 0.2 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.1 0.6 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.1 0.2 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.1 0.7 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.1 0.5 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.1 0.2 GO:1903722 regulation of centriole elongation(GO:1903722)
0.1 0.4 GO:0097056 selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
0.1 0.2 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.1 0.2 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.1 0.3 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730) positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.1 0.4 GO:0060750 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.1 0.2 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.1 0.4 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.1 0.2 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.0 0.5 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.2 GO:0061582 intestinal epithelial cell migration(GO:0061582)
0.0 0.2 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.5 GO:0045054 constitutive secretory pathway(GO:0045054)
0.0 1.0 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.0 GO:0046653 folic acid-containing compound biosynthetic process(GO:0009396) tetrahydrofolate interconversion(GO:0035999) tetrahydrofolate metabolic process(GO:0046653)
0.0 1.3 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.2 GO:0035188 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0 0.3 GO:0061084 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.0 0.9 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.1 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.0 0.2 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
0.0 0.1 GO:0022613 ribonucleoprotein complex biogenesis(GO:0022613)
0.0 0.2 GO:0051708 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.2 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
0.0 0.1 GO:0045829 negative regulation of isotype switching(GO:0045829)
0.0 0.1 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.0 0.1 GO:0002879 positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.0 0.3 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.6 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.1 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.0 0.2 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.0 GO:0060702 negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702)
0.0 0.1 GO:0060127 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) superior vena cava morphogenesis(GO:0060578)
0.0 0.1 GO:0021764 amygdala development(GO:0021764)
0.0 0.4 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.4 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.1 GO:0006429 glutaminyl-tRNA aminoacylation(GO:0006425) leucyl-tRNA aminoacylation(GO:0006429)
0.0 0.3 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.0 0.2 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.0 0.1 GO:0051866 general adaptation syndrome(GO:0051866)
0.0 0.3 GO:0045955 negative regulation of calcium ion-dependent exocytosis(GO:0045955)
0.0 0.3 GO:0048511 rhythmic process(GO:0048511)
0.0 0.1 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.0 0.1 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.0 0.2 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.1 GO:0051177 meiotic sister chromatid cohesion(GO:0051177)
0.0 0.1 GO:0060032 notochord regression(GO:0060032)
0.0 0.3 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.5 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.1 GO:0021503 neural fold bending(GO:0021503)
0.0 0.3 GO:0051612 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.1 GO:1990637 response to prolactin(GO:1990637)
0.0 0.1 GO:0043449 cellular alkene metabolic process(GO:0043449)
0.0 0.3 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.2 GO:0003322 pancreatic A cell development(GO:0003322)
0.0 0.3 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.1 GO:0033484 nitric oxide homeostasis(GO:0033484)
0.0 0.2 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.0 0.1 GO:1902568 regulation of eosinophil degranulation(GO:0043309) positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.0 0.3 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.3 GO:0000050 urea cycle(GO:0000050)
0.0 0.1 GO:0071373 cellular response to luteinizing hormone stimulus(GO:0071373)
0.0 0.3 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.1 GO:1903450 regulation of G1 to G0 transition(GO:1903450) positive regulation of G1 to G0 transition(GO:1903452)
0.0 0.1 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.1 GO:1902159 regulation of cyclic nucleotide-gated ion channel activity(GO:1902159)
0.0 0.2 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.1 GO:0035617 stress granule disassembly(GO:0035617)
0.0 0.2 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.1 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.3 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.1 GO:0035283 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.0 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.0 0.1 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.0 0.2 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.3 GO:0001553 luteinization(GO:0001553)
0.0 0.2 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.0 0.1 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.0 0.2 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.1 GO:1902962 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.0 0.1 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.5 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.1 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.1 GO:1904106 protein localization to microvillus(GO:1904106)
0.0 0.1 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.0 0.1 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.3 GO:0006105 succinate metabolic process(GO:0006105)
0.0 0.1 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.0 0.1 GO:1904235 regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904235) positive regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904237)
0.0 0.1 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.1 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.0 0.7 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.0 GO:1901340 negative regulation of store-operated calcium channel activity(GO:1901340)
0.0 0.3 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.0 0.4 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.0 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0 0.1 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 0.1 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.0 0.2 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.1 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.2 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.1 GO:0055096 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
0.0 0.2 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.0 0.1 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.0 0.2 GO:0060149 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
0.0 0.6 GO:0050427 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0 0.0 GO:1902990 mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.0 0.1 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 0.1 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.0 0.3 GO:0060973 cell migration involved in heart development(GO:0060973)
0.0 0.1 GO:0035754 B cell chemotaxis(GO:0035754)
0.0 0.1 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.0 0.1 GO:0090650 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.0 0.1 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.0 0.1 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.1 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.2 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0 0.1 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.1 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.4 GO:0000732 strand displacement(GO:0000732)
0.0 0.3 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.0 GO:0048075 positive regulation of eye pigmentation(GO:0048075)
0.0 0.1 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.0 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.0 0.2 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0 0.1 GO:1990441 negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990441)
0.0 0.2 GO:0072520 seminiferous tubule development(GO:0072520)
0.0 0.1 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.1 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.1 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.1 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.0 0.2 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.1 GO:0070897 DNA-templated transcriptional preinitiation complex assembly(GO:0070897)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0075341 host cell PML body(GO:0075341)
0.1 0.7 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.1 0.3 GO:0005873 plus-end kinesin complex(GO:0005873)
0.1 2.1 GO:1990023 mitotic spindle midzone(GO:1990023)
0.1 1.1 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 0.3 GO:0045257 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1 0.9 GO:0000322 storage vacuole(GO:0000322)
0.1 0.5 GO:0097452 GAIT complex(GO:0097452)
0.1 0.2 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.0 0.5 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.3 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.0 0.4 GO:0070081 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 0.4 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.0 0.1 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.0 0.3 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.0 0.5 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.2 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 0.2 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.0 0.9 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.3 GO:0033503 HULC complex(GO:0033503)
0.0 0.2 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.3 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.5 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.8 GO:0031143 pseudopodium(GO:0031143)
0.0 0.1 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.0 0.7 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.1 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.0 0.1 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 0.2 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.1 GO:0098536 deuterosome(GO:0098536)
0.0 0.1 GO:0031673 H zone(GO:0031673)
0.0 0.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.4 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.7 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.3 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.0 GO:1990423 RZZ complex(GO:1990423)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.1 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.2 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.2 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.1 GO:1990357 terminal web(GO:1990357)
0.0 0.2 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.3 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.1 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.4 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.2 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.1 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.0 1.5 GO:0005811 lipid particle(GO:0005811)
0.0 0.1 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.2 GO:0034464 BBSome(GO:0034464)
0.0 0.1 GO:0043679 axon terminus(GO:0043679)
0.0 0.9 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.1 GO:0000346 transcription export complex(GO:0000346)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.2 0.5 GO:0015235 cobalamin transporter activity(GO:0015235)
0.2 0.5 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.1 0.7 GO:0019776 Atg8 ligase activity(GO:0019776)
0.1 0.7 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.1 0.4 GO:0032427 GBD domain binding(GO:0032427)
0.1 0.9 GO:0043515 kinetochore binding(GO:0043515)
0.1 0.3 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177) 3 iron, 4 sulfur cluster binding(GO:0051538)
0.1 0.6 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 0.1 GO:0017129 triglyceride binding(GO:0017129)
0.1 0.4 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 0.4 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.1 0.3 GO:0032558 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.1 0.3 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 0.2 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142) phosphatidate cytidylyltransferase activity(GO:0004605)
0.1 0.8 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 1.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.1 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
0.0 0.2 GO:0070012 oligopeptidase activity(GO:0070012)
0.0 1.0 GO:0048156 tau protein binding(GO:0048156)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.2 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 0.4 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.3 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.2 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.0 0.1 GO:0098770 FBXO family protein binding(GO:0098770)
0.0 0.9 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.5 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 1.1 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.2 GO:0050436 microfibril binding(GO:0050436)
0.0 1.1 GO:0031489 myosin V binding(GO:0031489)
0.0 0.2 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974) S-adenosyl-L-methionine binding(GO:1904047)
0.0 0.1 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.0 0.1 GO:0004823 glutamine-tRNA ligase activity(GO:0004819) leucine-tRNA ligase activity(GO:0004823)
0.0 0.3 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.4 GO:0042731 PH domain binding(GO:0042731)
0.0 0.6 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.1 GO:0051908 double-stranded DNA 5'-3' exodeoxyribonuclease activity(GO:0051908)
0.0 0.1 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.0 0.1 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.0 0.3 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.3 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.2 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.1 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.5 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.1 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.1 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.3 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.8 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.3 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.6 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.3 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 1.2 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.3 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.2 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.1 GO:0030250 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0 0.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.6 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.1 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.6 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.2 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.3 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.2 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.1 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.0 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.0 1.2 GO:0019003 GDP binding(GO:0019003)
0.0 0.4 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.1 GO:0008526 phosphatidylcholine transporter activity(GO:0008525) phosphatidylinositol transporter activity(GO:0008526)
0.0 0.0 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.2 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.1 GO:0097677 STAT family protein binding(GO:0097677)
0.0 0.1 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.9 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.2 GO:0043121 neurotrophin binding(GO:0043121)
0.0 0.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.5 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.5 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.1 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.0 0.3 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.1 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.1 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.2 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.2 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.1 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.5 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.1 GO:0005549 odorant binding(GO:0005549)
0.0 0.3 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.1 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0 0.1 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.0 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.0 0.1 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.2 GO:0043274 phospholipase binding(GO:0043274)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.8 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 1.6 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.9 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.8 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.6 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.5 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.0 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.2 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 1.2 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.5 PID VEGFR1 PATHWAY VEGFR1 specific signals

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.6 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 1.3 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.5 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.8 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.6 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.6 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.5 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.5 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.0 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.3 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 0.3 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.5 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.5 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 1.0 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.9 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.8 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.7 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.6 REACTOME KINESINS Genes involved in Kinesins
0.0 0.7 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.3 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.3 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.2 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins