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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for CUX2

Z-value: 1.37

Motif logo

Transcription factors associated with CUX2

Gene Symbol Gene ID Gene Info
ENSG00000111249.9 cut like homeobox 2

Activity profile of CUX2 motif

Sorted Z-values of CUX2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_+_61151306 1.62 ENST00000580068.1
ENST00000580466.1
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr17_+_34171081 1.09 ENST00000585577.1
TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
chr19_-_58864848 1.09 ENST00000263100.3
alpha-1-B glycoprotein
chr19_+_507299 1.03 ENST00000359315.5
tubulin polyglutamylase complex subunit 1
chr14_-_81425828 0.93 ENST00000555529.1
ENST00000556042.1
ENST00000556981.1
centrosomal protein 128kDa
chr8_-_145754428 0.86 ENST00000527462.1
ENST00000313465.5
ENST00000524821.1
chromosome 8 open reading frame 82
chrY_+_15418467 0.85 ENST00000595988.1
Uncharacterized protein
chr17_+_67498396 0.72 ENST00000588110.1
mitogen-activated protein kinase kinase 6
chr12_+_7052974 0.72 ENST00000544681.1
ENST00000537087.1
chromosome 12 open reading frame 57
chr6_-_27799305 0.71 ENST00000357549.2
histone cluster 1, H4k
chr12_+_74931551 0.70 ENST00000519948.2
ataxin 7-like 3B
chr8_+_94752349 0.65 ENST00000391680.1
RBM12B antisense RNA 1
chr16_+_12059091 0.62 ENST00000562385.1
tumor necrosis factor receptor superfamily, member 17
chr1_+_200860122 0.59 ENST00000532631.1
ENST00000451872.2
chromosome 1 open reading frame 106
chr16_-_28634874 0.51 ENST00000395609.1
ENST00000350842.4
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr9_-_110540419 0.47 ENST00000398726.3
Uncharacterized protein
chr12_-_76879852 0.47 ENST00000548341.1
oxysterol binding protein-like 8
chr9_-_106087316 0.47 ENST00000411575.1
RP11-341A22.2
chr1_-_153950116 0.46 ENST00000368589.1
jumping translocation breakpoint
chr20_+_62492566 0.46 ENST00000369916.3
abhydrolase domain containing 16B
chr3_+_181429704 0.44 ENST00000431565.2
ENST00000325404.1
SRY (sex determining region Y)-box 2
chr22_+_30821732 0.44 ENST00000355143.4
mitochondrial fission process 1
chr19_+_41882466 0.44 ENST00000436170.2
transmembrane protein 91
chr4_+_109571800 0.43 ENST00000512478.2
oligosaccharyltransferase complex subunit (non-catalytic)
chr19_-_47287990 0.43 ENST00000593713.1
ENST00000598022.1
ENST00000434726.2
solute carrier family 1 (neutral amino acid transporter), member 5
chr2_+_27255806 0.42 ENST00000238788.9
ENST00000404032.3
transmembrane protein 214
chr22_+_24198890 0.41 ENST00000345044.6
solute carrier family 2 (facilitated glucose transporter), member 11
chr6_-_33548006 0.41 ENST00000374467.3
BCL2-antagonist/killer 1
chr9_-_130497565 0.41 ENST00000336067.6
ENST00000373281.5
ENST00000373284.5
ENST00000458505.3
torsin family 2, member A
chr11_+_44117219 0.39 ENST00000532479.1
ENST00000527014.1
exostosin glycosyltransferase 2
chr20_-_22566089 0.39 ENST00000377115.4
forkhead box A2
chr19_+_48248779 0.38 ENST00000246802.5
glioma tumor suppressor candidate region gene 2
chr11_+_34999328 0.38 ENST00000526309.1
pyruvate dehydrogenase complex, component X
chr16_-_4817129 0.37 ENST00000545009.1
ENST00000219478.6
zinc finger protein 500
chr12_+_47610315 0.37 ENST00000548348.1
ENST00000549500.1
PC-esterase domain containing 1B
chr2_+_217524323 0.37 ENST00000456764.1
insulin-like growth factor binding protein 2, 36kDa
chr11_+_110225855 0.36 ENST00000526605.1
ENST00000526703.1
RP11-347E10.1
chr12_-_10601963 0.36 ENST00000543893.1
killer cell lectin-like receptor subfamily C, member 1
chr7_-_3214287 0.35 ENST00000404626.3
LOC392621; Uncharacterized protein
chr12_+_48166978 0.34 ENST00000442218.2
solute carrier family 48 (heme transporter), member 1
chr22_+_20703829 0.33 ENST00000583722.1
family with sequence similarity 230, member A
chr17_+_67498295 0.33 ENST00000589295.1
mitogen-activated protein kinase kinase 6
chr6_-_33547975 0.33 ENST00000442998.2
ENST00000360661.5
BCL2-antagonist/killer 1
chr1_-_89591749 0.33 ENST00000370466.3
guanylate binding protein 2, interferon-inducible
chr15_+_75315896 0.33 ENST00000342932.3
ENST00000564923.1
ENST00000569562.1
ENST00000568649.1
phosphopantothenoylcysteine decarboxylase
chr1_+_75594119 0.33 ENST00000294638.5
LIM homeobox 8
chr17_+_17685422 0.32 ENST00000395774.1
retinoic acid induced 1
chr6_+_49518113 0.32 ENST00000529246.2
chromosome 6 open reading frame 141
chr5_-_43397184 0.32 ENST00000513525.1
chemokine (C-C motif) ligand 28
chrY_+_15815447 0.32 ENST00000284856.3
thymosin beta 4, Y-linked
chr2_-_228497888 0.31 ENST00000264387.4
ENST00000409066.1
chromosome 2 open reading frame 83
chr1_-_249120832 0.31 ENST00000366472.5
SH3-binding domain protein 5-like
chr6_-_32160622 0.31 ENST00000487761.1
ENST00000375040.3
G-protein signaling modulator 3
chr16_-_66584059 0.31 ENST00000417693.3
ENST00000544898.1
ENST00000569718.1
ENST00000527284.1
ENST00000299697.7
ENST00000451102.2
thymidine kinase 2, mitochondrial
chr19_-_16008880 0.31 ENST00000011989.7
ENST00000221700.6
cytochrome P450, family 4, subfamily F, polypeptide 2
chr5_+_140529630 0.31 ENST00000543635.1
protocadherin beta 6
chr3_+_25831567 0.30 ENST00000280701.3
ENST00000420173.2
3-oxoacyl-ACP synthase, mitochondrial
chr12_+_123944070 0.30 ENST00000412157.2
small nuclear ribonucleoprotein 35kDa (U11/U12)
chr1_-_24513737 0.30 ENST00000374421.3
ENST00000374418.3
ENST00000327535.1
ENST00000327575.2
interferon, lambda receptor 1
chr6_-_26285737 0.30 ENST00000377727.1
ENST00000289352.1
histone cluster 1, H4h
chr14_+_38033252 0.30 ENST00000554829.1
RP11-356O9.1
chr14_+_74004051 0.30 ENST00000557556.1
acyl-CoA thioesterase 1
chr1_+_45477901 0.29 ENST00000434478.1
uroporphyrinogen decarboxylase
chr8_-_8318847 0.29 ENST00000521218.1
CTA-398F10.2
chr3_+_186158169 0.29 ENST00000435548.1
ENST00000421006.1
RP11-78H24.1
chr4_+_109571740 0.29 ENST00000361564.4
oligosaccharyltransferase complex subunit (non-catalytic)
chr5_-_135290705 0.29 ENST00000274507.1
leukocyte cell-derived chemotaxin 2
chr1_+_196788887 0.29 ENST00000320493.5
ENST00000367424.4
ENST00000367421.3
complement factor H-related 1
complement factor H-related 2
chr1_+_155179012 0.29 ENST00000609421.1
metaxin 1
chr19_-_22018966 0.29 ENST00000599906.1
ENST00000354959.4
zinc finger protein 43
chr7_-_104909435 0.29 ENST00000357311.3
SRSF protein kinase 2
chr1_+_67632083 0.29 ENST00000347310.5
ENST00000371002.1
interleukin 23 receptor
chr16_-_30621663 0.28 ENST00000287461.3
zinc finger protein 689
chr5_-_135290651 0.28 ENST00000522943.1
ENST00000514447.2
leukocyte cell-derived chemotaxin 2
chr19_+_29704142 0.28 ENST00000587859.1
ENST00000590607.1
CTB-32O4.2
chr15_+_41057818 0.28 ENST00000558467.1
GTP cyclohydrolase I feedback regulator
chr11_-_82612678 0.28 ENST00000534631.1
ENST00000531801.1
prolylcarboxypeptidase (angiotensinase C)
chr19_+_49588677 0.28 ENST00000598984.1
ENST00000598441.1
small nuclear ribonucleoprotein 70kDa (U1)
chr11_-_58611957 0.28 ENST00000532258.1
glycine-N-acyltransferase-like 2
chr1_+_81106951 0.27 ENST00000443565.1
RP5-887A10.1
chr22_-_28392227 0.27 ENST00000431039.1
tetratricopeptide repeat domain 28
chr4_-_909521 0.27 ENST00000511229.1
cyclin G associated kinase
chr13_+_111855399 0.27 ENST00000426768.2
Rho guanine nucleotide exchange factor (GEF) 7
chr10_+_6779326 0.27 ENST00000417112.1
RP11-554I8.2
chr4_+_69681710 0.27 ENST00000265403.7
ENST00000458688.2
UDP glucuronosyltransferase 2 family, polypeptide B10
chr5_-_54988448 0.26 ENST00000503817.1
ENST00000512595.1
solute carrier family 38, member 9
chr19_-_10697895 0.26 ENST00000591240.1
ENST00000589684.1
ENST00000591676.1
ENST00000250244.6
ENST00000590923.1
adaptor-related protein complex 1, mu 2 subunit
chr7_+_102290772 0.26 ENST00000507450.1
speedy/RINGO cell cycle regulator family member E2B
chr3_+_8543393 0.26 ENST00000157600.3
ENST00000415597.1
ENST00000535732.1
LIM and cysteine-rich domains 1
chr8_+_120885949 0.26 ENST00000523492.1
ENST00000286234.5
DEP domain containing MTOR-interacting protein
chr9_-_131790550 0.26 ENST00000372554.4
ENST00000372564.3
SH3-domain GRB2-like endophilin B2
chr7_+_16828866 0.26 ENST00000597084.1
Uncharacterized protein
chr1_+_225600404 0.26 ENST00000366845.2
AC092811.1
chr17_-_72772462 0.25 ENST00000582870.1
ENST00000581136.1
ENST00000357814.3
ENST00000579218.1
ENST00000583476.1
ENST00000580301.1
ENST00000583757.1
ENST00000582524.1
N-acetyltransferase 9 (GCN5-related, putative)
chr2_+_120687335 0.25 ENST00000544261.1
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chr11_+_47279155 0.25 ENST00000444396.1
ENST00000457932.1
ENST00000412937.1
nuclear receptor subfamily 1, group H, member 3
chr2_+_9778872 0.25 ENST00000478468.1
RP11-521D12.1
chr19_-_13900972 0.25 ENST00000397557.1
Uncharacterized protein
chr11_-_65488260 0.25 ENST00000527610.1
ENST00000528220.1
ENST00000308418.4
ribonuclease H2, subunit C
chr17_-_4167142 0.24 ENST00000570535.1
ENST00000574367.1
ENST00000341657.4
ENST00000433651.1
ankyrin repeat and FYVE domain containing 1
chr12_+_28605426 0.24 ENST00000542801.1
coiled-coil domain containing 91
chr10_+_70980051 0.24 ENST00000354624.5
ENST00000395086.2
hexokinase domain containing 1
chr11_+_62623544 0.24 ENST00000377890.2
ENST00000377891.2
ENST00000377889.2
solute carrier family 3 (amino acid transporter heavy chain), member 2
chr19_+_36486078 0.24 ENST00000378887.2
succinate dehydrogenase complex assembly factor 1
chr1_-_153950164 0.24 ENST00000271843.4
jumping translocation breakpoint
chr3_-_197300194 0.24 ENST00000358186.2
ENST00000431056.1
3-hydroxybutyrate dehydrogenase, type 1
chr10_+_5238793 0.23 ENST00000263126.1
aldo-keto reductase family 1, member C4
chr4_-_40477766 0.23 ENST00000507180.1
RNA binding motif protein 47
chr11_-_559377 0.23 ENST00000486629.1
chromosome 11 open reading frame 35
chr20_-_36794938 0.23 ENST00000453095.1
transglutaminase 2
chr22_+_18560743 0.23 ENST00000399744.3
peroxisomal biogenesis factor 26
chrX_-_107682702 0.23 ENST00000372216.4
collagen, type IV, alpha 6
chr16_-_2314222 0.23 ENST00000566397.1
RNA binding protein S1, serine-rich domain
chr12_+_31226779 0.22 ENST00000542838.1
ENST00000407793.2
ENST00000251758.5
ENST00000228264.6
ENST00000438391.2
ENST00000415475.2
ENST00000545668.1
ENST00000350437.4
DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11
chr10_-_90751038 0.22 ENST00000458159.1
ENST00000415557.1
ENST00000458208.1
actin, alpha 2, smooth muscle, aorta
chr5_-_149829294 0.22 ENST00000401695.3
ribosomal protein S14
chr7_-_135612198 0.22 ENST00000589735.1
leucine zipper protein 6
chr2_+_58655461 0.22 ENST00000429095.1
ENST00000429664.1
ENST00000452840.1
long intergenic non-protein coding RNA 1122
chr3_-_120365866 0.22 ENST00000475447.2
homogentisate 1,2-dioxygenase
chr19_+_41882598 0.21 ENST00000447302.2
ENST00000544232.1
ENST00000542945.1
ENST00000540732.1
transmembrane protein 91
2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial; Uncharacterized protein
chr19_+_49588690 0.21 ENST00000221448.5
small nuclear ribonucleoprotein 70kDa (U1)
chr8_+_77593448 0.21 ENST00000521891.2
zinc finger homeobox 4
chr1_+_16083154 0.21 ENST00000375771.1
filamin binding LIM protein 1
chr4_+_15341442 0.21 ENST00000397700.2
ENST00000295297.4
C1q and tumor necrosis factor related protein 7
chr18_+_61445007 0.21 ENST00000447428.1
ENST00000546027.1
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr19_-_44124019 0.21 ENST00000300811.3
zinc finger protein 428
chr22_+_24407642 0.21 ENST00000454754.1
ENST00000263119.5
calcineurin binding protein 1
chr9_+_35673853 0.21 ENST00000378357.4
carbonic anhydrase IX
chr6_+_26273144 0.20 ENST00000377733.2
histone cluster 1, H2bi
chr20_+_58571419 0.20 ENST00000244049.3
ENST00000350849.6
ENST00000456106.1
cadherin 26
chr16_-_66583994 0.20 ENST00000564917.1
thymidine kinase 2, mitochondrial
chr1_+_8378140 0.20 ENST00000377479.2
solute carrier family 45, member 1
chr11_+_92085262 0.20 ENST00000298047.6
ENST00000409404.2
ENST00000541502.1
FAT atypical cadherin 3
chr20_-_43133491 0.20 ENST00000411544.1
serine incorporator 3
chr9_-_21482312 0.20 ENST00000448696.3
interferon, epsilon
chr17_+_4046964 0.20 ENST00000573984.1
cytochrome b5 domain containing 2
chr5_-_133706695 0.19 ENST00000521755.1
ENST00000523054.1
ENST00000435240.2
ENST00000609654.1
ENST00000536186.1
ENST00000609383.1
cyclin-dependent kinase-like 3
chr19_+_21106081 0.19 ENST00000300540.3
ENST00000595854.1
ENST00000601284.1
ENST00000328178.8
ENST00000599885.1
ENST00000596476.1
ENST00000345030.6
zinc finger protein 85
chr5_-_150727111 0.19 ENST00000335244.4
ENST00000521967.1
solute carrier family 36 (proton/amino acid symporter), member 2
chr11_-_75917569 0.19 ENST00000322563.3
wingless-type MMTV integration site family, member 11
chr17_-_79876010 0.19 ENST00000328666.6
sirtuin 7
chr20_-_52612705 0.19 ENST00000434986.2
breast carcinoma amplified sequence 1
chr21_+_43619796 0.19 ENST00000398457.2
ATP-binding cassette, sub-family G (WHITE), member 1
chr2_+_217082311 0.19 ENST00000597904.1
RP11-566E18.3
chr18_-_69246186 0.18 ENST00000568095.1
RP11-510D19.1
chr15_+_89631647 0.17 ENST00000569550.1
ENST00000565066.1
ENST00000565973.1
abhydrolase domain containing 2
chr11_-_59633951 0.17 ENST00000257264.3
transcobalamin I (vitamin B12 binding protein, R binder family)
chr12_-_118490217 0.17 ENST00000542304.1
WD repeat and SOCS box containing 2
chr10_+_99205959 0.17 ENST00000352634.4
ENST00000353979.3
ENST00000370842.2
ENST00000345745.5
zinc finger, DHHC-type containing 16
chr19_-_4400415 0.17 ENST00000598564.1
ENST00000417295.2
ENST00000269886.3
SH3-domain GRB2-like 1
chr1_+_207262881 0.17 ENST00000451804.2
complement component 4 binding protein, beta
chr6_+_131958436 0.17 ENST00000357639.3
ENST00000543135.1
ENST00000427148.2
ENST00000358229.5
ectonucleotide pyrophosphatase/phosphodiesterase 3
chrX_-_77225135 0.17 ENST00000458128.1
phosphoglycerate mutase family member 4
chr5_-_55412774 0.17 ENST00000434982.2
ankyrin repeat domain 55
chr1_-_45476944 0.16 ENST00000372172.4
HECT domain containing E3 ubiquitin protein ligase 3
chr6_-_138539627 0.16 ENST00000527246.2
prostate and breast cancer overexpressed 1
chr7_-_92777606 0.16 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
sterile alpha motif domain containing 9-like
chr8_-_623547 0.16 ENST00000522893.1
glutamate-rich 1
chr3_+_39424828 0.16 ENST00000273158.4
ENST00000431510.1
solute carrier family 25, member 38
chr2_-_86333244 0.16 ENST00000263857.6
ENST00000409681.1
polymerase (RNA) I polypeptide A, 194kDa
chr19_-_55677999 0.16 ENST00000532817.1
ENST00000527223.2
ENST00000391720.4
dynein, axonemal, assembly factor 3
chr20_-_44516256 0.16 ENST00000372519.3
spermatogenesis associated 25
chr19_+_48216600 0.16 ENST00000263277.3
ENST00000538399.1
EH-domain containing 2
chr22_-_22337204 0.16 ENST00000430142.1
ENST00000357179.5
topoisomerase (DNA) III beta
chr5_-_149829314 0.16 ENST00000407193.1
ribosomal protein S14
chr1_+_207262627 0.15 ENST00000391923.1
complement component 4 binding protein, beta
chr6_-_31613280 0.15 ENST00000453833.1
BCL2-associated athanogene 6
chr16_-_740354 0.15 ENST00000293883.4
WD repeat domain 24
chr11_+_44117099 0.15 ENST00000533608.1
exostosin glycosyltransferase 2
chr1_+_73771844 0.15 ENST00000440762.1
ENST00000444827.1
ENST00000415686.1
ENST00000411903.1
RP4-598G3.1
chr19_+_29493486 0.15 ENST00000589821.1
CTD-2081K17.2
chr6_+_36839616 0.15 ENST00000359359.2
ENST00000510325.2
chromosome 6 open reading frame 89
chr20_-_43150601 0.15 ENST00000541235.1
ENST00000255175.1
ENST00000342374.4
serine incorporator 3
chr19_-_6433765 0.15 ENST00000321510.6
solute carrier family 25, member 41
chr11_+_101983176 0.15 ENST00000524575.1
Yes-associated protein 1
chr6_+_42847649 0.15 ENST00000424341.2
ENST00000602561.1
ribosomal protein L7-like 1
chr4_+_110736659 0.15 ENST00000394631.3
ENST00000226796.6
GAR1 ribonucleoprotein
chr14_+_29241910 0.15 ENST00000399387.4
ENST00000552957.1
ENST00000548213.1
chromosome 14 open reading frame 23
chr1_+_26036093 0.15 ENST00000374329.1
mannosidase, alpha, class 1C, member 1
chr10_+_99205894 0.15 ENST00000370854.3
ENST00000393760.1
ENST00000414567.1
ENST00000370846.4
zinc finger, DHHC-type containing 16
chr5_-_149829244 0.14 ENST00000312037.5
ribosomal protein S14
chr5_+_60933634 0.14 ENST00000505642.1
chromosome 5 open reading frame 64
chr7_+_133615169 0.14 ENST00000541309.1
exocyst complex component 4
chr1_-_106161540 0.14 ENST00000420901.1
ENST00000610126.1
ENST00000435253.2
RP11-251P6.1
chr1_-_46664074 0.14 ENST00000371986.3
ENST00000371984.3
protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)
chr8_-_66474884 0.14 ENST00000520902.1
CTD-3025N20.2
chr2_+_131769256 0.14 ENST00000355771.3
Rho guanine nucleotide exchange factor (GEF) 4
chr4_+_74275057 0.14 ENST00000511370.1
albumin
chr15_+_78370140 0.14 ENST00000409568.2
SH2 domain containing 7
chr15_-_75932528 0.14 ENST00000403490.1
IMP3, U3 small nucleolar ribonucleoprotein, homolog (yeast)
chr3_-_150690786 0.14 ENST00000327047.1
clarin 1
chr10_+_104503727 0.14 ENST00000448841.1
WW domain binding protein 1-like
chr9_+_105757590 0.14 ENST00000374798.3
ENST00000487798.1
cylicin, basic protein of sperm head cytoskeleton 2
chr6_+_88054530 0.14 ENST00000388923.4
chromosome 6 open reading frame 163
chr4_-_85771168 0.14 ENST00000514071.1
WD repeat and FYVE domain containing 3
chr11_+_60145948 0.14 ENST00000300184.3
ENST00000358246.1
membrane-spanning 4-domains, subfamily A, member 7
chr15_-_64673665 0.14 ENST00000300035.4
KIAA0101
chr6_+_31105426 0.14 ENST00000547221.1
psoriasis susceptibility 1 candidate 1
chr1_+_44870866 0.14 ENST00000355387.2
ENST00000361799.2
ring finger protein 220
chr16_-_740419 0.13 ENST00000248142.6
WD repeat domain 24

Network of associatons between targets according to the STRING database.

First level regulatory network of CUX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0048597 B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597)
0.2 1.1 GO:0072709 cellular response to sorbitol(GO:0072709)
0.1 0.4 GO:1904995 negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995)
0.1 0.4 GO:0010585 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.1 0.5 GO:0046092 deoxycytidine metabolic process(GO:0046092)
0.1 0.4 GO:0045013 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.1 0.3 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
0.1 0.3 GO:0043095 regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.1 0.8 GO:0007288 sperm axoneme assembly(GO:0007288)
0.1 0.5 GO:0061084 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.1 0.2 GO:0034553 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.1 0.2 GO:1904976 response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976)
0.1 0.3 GO:0042361 menaquinone catabolic process(GO:0042361) vitamin K catabolic process(GO:0042377)
0.1 0.3 GO:1905224 clathrin-coated pit assembly(GO:1905224)
0.1 0.3 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.1 0.2 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.1 0.3 GO:0036343 psychomotor behavior(GO:0036343)
0.1 0.3 GO:0035063 nuclear speck organization(GO:0035063)
0.1 0.2 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.1 0.3 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
0.1 0.3 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.0 0.1 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.0 0.6 GO:0032494 response to peptidoglycan(GO:0032494)
0.0 0.2 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.0 0.2 GO:0045897 positive regulation of transcription during mitosis(GO:0045897)
0.0 0.1 GO:0001897 cytolysis by symbiont of host cells(GO:0001897)
0.0 0.2 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.0 0.3 GO:0002155 regulation of thyroid hormone mediated signaling pathway(GO:0002155) kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353)
0.0 0.4 GO:0009597 detection of virus(GO:0009597)
0.0 0.4 GO:0045959 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.0 0.3 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.0 0.2 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.4 GO:0001714 endodermal cell fate specification(GO:0001714)
0.0 0.4 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.2 GO:0090131 mesenchyme migration(GO:0090131)
0.0 0.2 GO:0060356 leucine import(GO:0060356)
0.0 0.6 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.4 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.4 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.1 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.0 0.2 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.2 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.0 0.1 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.0 0.1 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.1 GO:2001202 regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904235) positive regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904237) negative regulation of transforming growth factor-beta secretion(GO:2001202)
0.0 0.3 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 0.2 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.1 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.0 0.1 GO:0032661 regulation of interleukin-18 production(GO:0032661)
0.0 0.5 GO:0006068 ethanol catabolic process(GO:0006068)
0.0 0.2 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.1 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.0 0.1 GO:0070409 carbamoyl phosphate metabolic process(GO:0070408) carbamoyl phosphate biosynthetic process(GO:0070409) response to ammonia(GO:1903717) cellular response to ammonia(GO:1903718)
0.0 0.1 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 0.2 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.1 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.0 0.2 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.0 0.2 GO:1904749 regulation of protein localization to nucleolus(GO:1904749)
0.0 0.1 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.0 0.2 GO:0015808 L-alanine transport(GO:0015808) proline transmembrane transport(GO:0035524)
0.0 0.1 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.5 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.1 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.1 GO:0006147 guanine catabolic process(GO:0006147)
0.0 0.2 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.0 0.3 GO:0015886 heme transport(GO:0015886)
0.0 0.4 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.1 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.0 0.1 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.0 0.1 GO:0035701 hematopoietic stem cell migration(GO:0035701)
0.0 0.2 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.0 0.1 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.0 0.1 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.1 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.2 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.2 GO:0045046 protein import into peroxisome membrane(GO:0045046)
0.0 0.3 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.2 GO:1904379 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.3 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0 0.2 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.0 GO:0007113 endomitotic cell cycle(GO:0007113)
0.0 0.3 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.2 GO:0006824 cobalt ion transport(GO:0006824)
0.0 0.1 GO:0048388 glycerol transport(GO:0015793) endosomal lumen acidification(GO:0048388)
0.0 0.3 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.1 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.0 0.2 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.0 GO:0017143 insecticide metabolic process(GO:0017143) cellular response to luteinizing hormone stimulus(GO:0071373)
0.0 0.4 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.1 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.0 0.1 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.2 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.0 GO:0060488 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.0 0.2 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.1 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.0 0.2 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.2 GO:0015816 glycine transport(GO:0015816)
0.0 0.0 GO:0070839 regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395) divalent metal ion export(GO:0070839)
0.0 0.3 GO:0014850 response to muscle activity(GO:0014850)
0.0 0.1 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0 0.6 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.1 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.1 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.3 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.1 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.1 0.3 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.1 0.2 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.1 0.6 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.1 0.8 GO:0000243 commitment complex(GO:0000243)
0.1 0.3 GO:0001674 female germ cell nucleus(GO:0001674)
0.1 0.7 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.4 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.2 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.7 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.1 GO:0097635 extrinsic component of autophagosome membrane(GO:0097635)
0.0 0.1 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.0 0.1 GO:0034457 Mpp10 complex(GO:0034457)
0.0 0.3 GO:0061574 ASAP complex(GO:0061574)
0.0 0.2 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.3 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.3 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.1 GO:0090661 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.2 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.3 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.2 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.1 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.1 GO:0000811 GINS complex(GO:0000811)
0.0 0.2 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.2 GO:0000322 storage vacuole(GO:0000322)
0.0 0.1 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.1 0.6 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.1 1.0 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.1 0.3 GO:0097258 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.1 0.3 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
0.1 0.3 GO:0004853 uroporphyrinogen decarboxylase activity(GO:0004853)
0.1 0.3 GO:0042019 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.1 0.3 GO:0044549 GTP cyclohydrolase binding(GO:0044549)
0.1 0.3 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.1 0.5 GO:0004137 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.1 0.2 GO:0045142 triplex DNA binding(GO:0045142)
0.1 0.3 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.1 0.5 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894) steroid sulfotransferase activity(GO:0050294)
0.1 0.2 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.1 0.2 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.1 0.4 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.5 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.2 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.0 0.4 GO:0004738 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 0.2 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.0 0.7 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.2 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.5 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.1 GO:0002113 interleukin-33 binding(GO:0002113)
0.0 0.2 GO:0022858 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.0 0.2 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.1 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.1 GO:0047223 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223)
0.0 0.4 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.4 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.2 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.1 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.0 0.1 GO:0052591 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.0 1.1 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.4 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.1 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.0 0.3 GO:0032810 sterol response element binding(GO:0032810)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.2 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.4 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.1 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.0 0.1 GO:0000384 first spliceosomal transesterification activity(GO:0000384)
0.0 0.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.2 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.5 GO:0051400 BH domain binding(GO:0051400)
0.0 0.1 GO:0008431 vitamin E binding(GO:0008431)
0.0 0.1 GO:0008892 guanine deaminase activity(GO:0008892)
0.0 0.1 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.3 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.0 GO:0031177 phosphopantetheine binding(GO:0031177)
0.0 0.1 GO:0004088 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.0 0.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.3 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.5 GO:0035198 miRNA binding(GO:0035198)
0.0 0.4 GO:0008009 chemokine activity(GO:0008009)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.2 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.1 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.3 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.2 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.3 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.2 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.1 GO:0052828 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.7 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.1 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.9 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 1.1 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.4 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.5 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.5 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.4 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.5 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.9 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.3 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.3 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.7 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.4 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.3 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.4 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells