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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for DBX2_HLX

Z-value: 0.57

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Transcription factors associated with DBX2_HLX

Gene Symbol Gene ID Gene Info
DBX2
ENSG00000185610.6 developing brain homeobox 2
HLX
ENSG00000136630.11 H2.0 like homeobox

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HLXhg19_v2_chr1_+_221051699_2210516990.881.2e-01Click!

Activity profile of DBX2_HLX motif

Sorted Z-values of DBX2_HLX motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_10978957 0.44 ENST00000240619.2
TAS2R10
taste receptor, type 2, member 10
chr21_+_33671264 0.37 ENST00000339944.4
MRAP
melanocortin 2 receptor accessory protein
chr11_+_5710919 0.36 ENST00000379965.3
ENST00000425490.1
TRIM22
tripartite motif containing 22
chr16_+_12059091 0.35 ENST00000562385.1
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr8_-_145754428 0.32 ENST00000527462.1
ENST00000313465.5
ENST00000524821.1
C8orf82
chromosome 8 open reading frame 82
chr9_-_21482312 0.26 ENST00000448696.3
IFNE
interferon, epsilon
chr1_+_117963209 0.25 ENST00000449370.2
MAN1A2
mannosidase, alpha, class 1A, member 2
chr7_+_138915102 0.25 ENST00000486663.1
UBN2
ubinuclein 2
chr17_+_61151306 0.24 ENST00000580068.1
ENST00000580466.1
TANC2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr19_-_3557570 0.23 ENST00000355415.2
MFSD12
major facilitator superfamily domain containing 12
chr4_-_89442940 0.19 ENST00000527353.1
PIGY
phosphatidylinositol glycan anchor biosynthesis, class Y
chr22_-_39268308 0.15 ENST00000407418.3
CBX6
chromobox homolog 6
chr12_-_85430024 0.14 ENST00000547836.1
ENST00000532498.2
TSPAN19
tetraspanin 19
chr19_+_50016610 0.14 ENST00000596975.1
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr11_-_327537 0.14 ENST00000602735.1
IFITM3
interferon induced transmembrane protein 3
chr2_+_135596180 0.14 ENST00000283054.4
ENST00000392928.1
ACMSD
aminocarboxymuconate semialdehyde decarboxylase
chr19_+_50016411 0.14 ENST00000426395.3
ENST00000600273.1
ENST00000599988.1
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr16_-_66583994 0.13 ENST00000564917.1
TK2
thymidine kinase 2, mitochondrial
chr1_-_183538319 0.13 ENST00000420553.1
ENST00000419402.1
NCF2
neutrophil cytosolic factor 2
chr3_-_114790179 0.12 ENST00000462705.1
ZBTB20
zinc finger and BTB domain containing 20
chr13_-_45048386 0.12 ENST00000472477.1
TSC22D1
TSC22 domain family, member 1
chr1_+_76251912 0.12 ENST00000370826.3
RABGGTB
Rab geranylgeranyltransferase, beta subunit
chr19_-_22018966 0.12 ENST00000599906.1
ENST00000354959.4
ZNF43
zinc finger protein 43
chr5_+_175288631 0.12 ENST00000509837.1
CPLX2
complexin 2
chr6_+_30029008 0.12 ENST00000332435.5
ENST00000376782.2
ENST00000359374.4
ENST00000376785.2
ZNRD1
zinc ribbon domain containing 1
chr22_+_30821732 0.12 ENST00000355143.4
MTFP1
mitochondrial fission process 1
chr6_-_25874440 0.12 ENST00000361703.6
ENST00000397060.4
SLC17A3
solute carrier family 17 (organic anion transporter), member 3
chr5_+_102200948 0.12 ENST00000511477.1
ENST00000506006.1
ENST00000509832.1
PAM
peptidylglycine alpha-amidating monooxygenase
chr3_+_138340049 0.11 ENST00000464668.1
FAIM
Fas apoptotic inhibitory molecule
chr7_+_13141010 0.11 ENST00000443947.1
AC011288.2
AC011288.2
chrM_-_14670 0.11 ENST00000361681.2
MT-ND6
mitochondrially encoded NADH dehydrogenase 6
chr4_+_71019903 0.11 ENST00000344526.5
C4orf40
chromosome 4 open reading frame 40
chr4_+_147096837 0.11 ENST00000296581.5
ENST00000502781.1
LSM6
LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr16_-_66584059 0.11 ENST00000417693.3
ENST00000544898.1
ENST00000569718.1
ENST00000527284.1
ENST00000299697.7
ENST00000451102.2
TK2
thymidine kinase 2, mitochondrial
chr16_-_28937027 0.11 ENST00000358201.4
RABEP2
rabaptin, RAB GTPase binding effector protein 2
chr2_+_135596106 0.11 ENST00000356140.5
ACMSD
aminocarboxymuconate semialdehyde decarboxylase
chr7_-_44122063 0.10 ENST00000335195.6
ENST00000395831.3
ENST00000414235.1
ENST00000452049.1
ENST00000242248.5
POLM
polymerase (DNA directed), mu
chr10_-_22292675 0.10 ENST00000376946.1
DNAJC1
DnaJ (Hsp40) homolog, subfamily C, member 1
chr11_+_327171 0.10 ENST00000534483.1
ENST00000524824.1
ENST00000531076.1
RP11-326C3.12
RP11-326C3.12
chrM_+_8366 0.10 ENST00000361851.1
MT-ATP8
mitochondrially encoded ATP synthase 8
chr19_-_58864848 0.10 ENST00000263100.3
A1BG
alpha-1-B glycoprotein
chrX_-_77225135 0.10 ENST00000458128.1
PGAM4
phosphoglycerate mutase family member 4
chr17_+_17685422 0.09 ENST00000395774.1
RAI1
retinoic acid induced 1
chr2_-_211342292 0.09 ENST00000448951.1
LANCL1
LanC lantibiotic synthetase component C-like 1 (bacterial)
chr6_-_47445214 0.09 ENST00000604014.1
RP11-385F7.1
RP11-385F7.1
chr9_-_3469181 0.09 ENST00000366116.2
AL365202.1
Uncharacterized protein
chr4_+_87857538 0.09 ENST00000511442.1
AFF1
AF4/FMR2 family, member 1
chr10_+_91152303 0.09 ENST00000371804.3
IFIT1
interferon-induced protein with tetratricopeptide repeats 1
chr1_-_89591749 0.09 ENST00000370466.3
GBP2
guanylate binding protein 2, interferon-inducible
chr9_+_67977438 0.09 ENST00000456982.1
RP11-195B21.3
Protein LOC644249
chr2_+_161993412 0.09 ENST00000259075.2
ENST00000432002.1
TANK
TRAF family member-associated NFKB activator
chr11_+_45825616 0.09 ENST00000442528.2
ENST00000456334.1
ENST00000526817.1
SLC35C1
solute carrier family 35 (GDP-fucose transporter), member C1
chr1_+_221051699 0.09 ENST00000366903.6
HLX
H2.0-like homeobox
chr1_-_108743471 0.08 ENST00000569674.1
SLC25A24
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
chr11_-_47521309 0.08 ENST00000535982.1
CELF1
CUGBP, Elav-like family member 1
chr12_+_14572070 0.08 ENST00000545769.1
ENST00000428217.2
ENST00000396279.2
ENST00000542514.1
ENST00000536279.1
ATF7IP
activating transcription factor 7 interacting protein
chr11_-_559377 0.08 ENST00000486629.1
C11orf35
chromosome 11 open reading frame 35
chr2_-_203735484 0.08 ENST00000420558.1
ENST00000418208.1
ICA1L
islet cell autoantigen 1,69kDa-like
chr14_-_54425475 0.08 ENST00000559642.1
BMP4
bone morphogenetic protein 4
chr6_+_114178512 0.08 ENST00000368635.4
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr2_+_208414985 0.08 ENST00000414681.1
CREB1
cAMP responsive element binding protein 1
chr18_+_61445205 0.08 ENST00000431370.1
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr12_+_21207503 0.07 ENST00000545916.1
SLCO1B7
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr9_+_131549610 0.07 ENST00000223865.8
TBC1D13
TBC1 domain family, member 13
chr8_+_120885949 0.07 ENST00000523492.1
ENST00000286234.5
DEPTOR
DEP domain containing MTOR-interacting protein
chr1_+_196788887 0.07 ENST00000320493.5
ENST00000367424.4
ENST00000367421.3
CFHR1
CFHR2
complement factor H-related 1
complement factor H-related 2
chr21_-_16125773 0.07 ENST00000454128.2
AF127936.3
AF127936.3
chr2_-_183106641 0.07 ENST00000346717.4
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr16_-_28634874 0.07 ENST00000395609.1
ENST00000350842.4
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr9_-_95055923 0.07 ENST00000430417.1
IARS
isoleucyl-tRNA synthetase
chr8_-_124741451 0.07 ENST00000520519.1
ANXA13
annexin A13
chr8_-_112039643 0.07 ENST00000524283.1
RP11-946L20.2
RP11-946L20.2
chr1_-_204183071 0.07 ENST00000308302.3
GOLT1A
golgi transport 1A
chr15_+_67418047 0.07 ENST00000540846.2
SMAD3
SMAD family member 3
chr1_-_168464875 0.07 ENST00000422253.1
RP5-968D22.3
RP5-968D22.3
chr5_+_157158205 0.06 ENST00000231198.7
THG1L
tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
chr11_+_5711010 0.06 ENST00000454828.1
TRIM22
tripartite motif containing 22
chr14_+_52164675 0.06 ENST00000555936.1
FRMD6
FERM domain containing 6
chr16_-_29934558 0.06 ENST00000568995.1
ENST00000566413.1
KCTD13
potassium channel tetramerization domain containing 13
chr17_+_74463650 0.06 ENST00000392492.3
AANAT
aralkylamine N-acetyltransferase
chr6_+_26087509 0.06 ENST00000397022.3
ENST00000353147.5
ENST00000352392.4
ENST00000349999.4
ENST00000317896.7
ENST00000357618.5
ENST00000470149.1
ENST00000336625.8
ENST00000461397.1
ENST00000488199.1
HFE
hemochromatosis
chr22_+_23487513 0.06 ENST00000263116.2
ENST00000341989.4
RAB36
RAB36, member RAS oncogene family
chr20_-_33735070 0.06 ENST00000374491.3
ENST00000542871.1
ENST00000374492.3
EDEM2
ER degradation enhancer, mannosidase alpha-like 2
chr17_-_7760457 0.06 ENST00000576384.1
LSMD1
LSM domain containing 1
chr5_-_175388327 0.06 ENST00000432305.2
ENST00000505969.1
THOC3
THO complex 3
chr13_-_110438914 0.06 ENST00000375856.3
IRS2
insulin receptor substrate 2
chr11_+_44117219 0.06 ENST00000532479.1
ENST00000527014.1
EXT2
exostosin glycosyltransferase 2
chr1_+_160370344 0.06 ENST00000368061.2
VANGL2
VANGL planar cell polarity protein 2
chr12_+_57623477 0.06 ENST00000557487.1
ENST00000555634.1
ENST00000556689.1
SHMT2
serine hydroxymethyltransferase 2 (mitochondrial)
chr1_+_151253991 0.06 ENST00000443959.1
ZNF687
zinc finger protein 687
chr2_-_37068530 0.06 ENST00000593798.1
AC007382.1
Uncharacterized protein
chr10_-_63995871 0.06 ENST00000315289.2
RTKN2
rhotekin 2
chr11_+_100784231 0.06 ENST00000531183.1
ARHGAP42
Rho GTPase activating protein 42
chr7_-_92777606 0.06 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
SAMD9L
sterile alpha motif domain containing 9-like
chr10_-_53459319 0.06 ENST00000331173.4
CSTF2T
cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
chr22_+_46476192 0.06 ENST00000443490.1
FLJ27365
hsa-mir-4763
chrX_+_150565038 0.06 ENST00000370361.1
VMA21
VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)
chr1_-_110950564 0.06 ENST00000256644.4
LAMTOR5
late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
chr11_-_111649015 0.06 ENST00000529841.1
RP11-108O10.2
RP11-108O10.2
chrX_+_55744228 0.06 ENST00000262850.7
RRAGB
Ras-related GTP binding B
chr16_-_21875424 0.05 ENST00000541674.1
NPIPB4
nuclear pore complex interacting protein family, member B4
chr14_-_67826538 0.05 ENST00000553687.1
ATP6V1D
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
chr4_-_40477766 0.05 ENST00000507180.1
RBM47
RNA binding motif protein 47
chr8_-_133637624 0.05 ENST00000522789.1
LRRC6
leucine rich repeat containing 6
chr2_-_87248975 0.05 ENST00000409310.2
ENST00000355705.3
PLGLB1
plasminogen-like B1
chrM_+_10464 0.05 ENST00000361335.1
MT-ND4L
mitochondrially encoded NADH dehydrogenase 4L
chr1_+_149239529 0.05 ENST00000457216.2
RP11-403I13.4
RP11-403I13.4
chr4_+_186990298 0.05 ENST00000296795.3
ENST00000513189.1
TLR3
toll-like receptor 3
chrX_+_9502971 0.05 ENST00000452824.1
TBL1X
transducin (beta)-like 1X-linked
chr2_+_201987200 0.05 ENST00000425030.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr17_+_67759813 0.05 ENST00000587241.1
AC003051.1
AC003051.1
chr8_-_42396185 0.05 ENST00000518717.1
SLC20A2
solute carrier family 20 (phosphate transporter), member 2
chr1_-_89357179 0.05 ENST00000448623.1
ENST00000418217.1
ENST00000370500.5
GTF2B
general transcription factor IIB
chrM_+_10053 0.05 ENST00000361227.2
MT-ND3
mitochondrially encoded NADH dehydrogenase 3
chr3_-_150421752 0.05 ENST00000498386.1
FAM194A
family with sequence similarity 194, member A
chr14_+_35591509 0.05 ENST00000604073.1
KIAA0391
KIAA0391
chr9_+_131549483 0.05 ENST00000372648.5
ENST00000539497.1
TBC1D13
TBC1 domain family, member 13
chr5_+_43602750 0.05 ENST00000505678.2
ENST00000512422.1
ENST00000264663.5
NNT
nicotinamide nucleotide transhydrogenase
chr22_-_50970919 0.05 ENST00000329363.4
ENST00000437588.1
ODF3B
outer dense fiber of sperm tails 3B
chr4_+_26324474 0.05 ENST00000514675.1
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr4_-_177116772 0.05 ENST00000280191.2
SPATA4
spermatogenesis associated 4
chr1_+_225600404 0.05 ENST00000366845.2
AC092811.1
AC092811.1
chr8_-_116504448 0.05 ENST00000518018.1
TRPS1
trichorhinophalangeal syndrome I
chr7_-_22862406 0.05 ENST00000372879.4
TOMM7
translocase of outer mitochondrial membrane 7 homolog (yeast)
chr3_-_112564797 0.05 ENST00000398214.1
ENST00000448932.1
CD200R1L
CD200 receptor 1-like
chr5_-_33297946 0.05 ENST00000510327.1
CTD-2066L21.3
CTD-2066L21.3
chr11_-_64684672 0.05 ENST00000377264.3
ENST00000421419.2
ATG2A
autophagy related 2A
chr8_+_109455830 0.05 ENST00000524143.1
EMC2
ER membrane protein complex subunit 2
chr2_+_120687335 0.05 ENST00000544261.1
PTPN4
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chr2_+_234580499 0.05 ENST00000354728.4
UGT1A9
UDP glucuronosyltransferase 1 family, polypeptide A9
chr1_-_160549235 0.05 ENST00000368054.3
ENST00000368048.3
ENST00000311224.4
ENST00000368051.3
ENST00000534968.1
CD84
CD84 molecule
chr6_+_34204642 0.05 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
HMGA1
high mobility group AT-hook 1
chr12_+_9066472 0.05 ENST00000538657.1
PHC1
polyhomeotic homolog 1 (Drosophila)
chr3_-_148939598 0.05 ENST00000455472.3
CP
ceruloplasmin (ferroxidase)
chr15_-_99789736 0.05 ENST00000560235.1
ENST00000394132.2
ENST00000560860.1
ENST00000558078.1
ENST00000394136.1
ENST00000262074.4
ENST00000558613.1
ENST00000394130.1
ENST00000560772.1
TTC23
tetratricopeptide repeat domain 23
chr5_-_146781153 0.05 ENST00000520473.1
DPYSL3
dihydropyrimidinase-like 3
chr17_+_29664830 0.05 ENST00000444181.2
ENST00000417592.2
NF1
neurofibromin 1
chr17_+_8191815 0.04 ENST00000226105.6
ENST00000407006.4
ENST00000580434.1
ENST00000439238.3
RANGRF
RAN guanine nucleotide release factor
chr2_+_74685413 0.04 ENST00000233615.2
WBP1
WW domain binding protein 1
chr2_-_70520539 0.04 ENST00000482975.2
ENST00000438261.1
SNRPG
small nuclear ribonucleoprotein polypeptide G
chr11_+_110300607 0.04 ENST00000260270.2
FDX1
ferredoxin 1
chr16_-_66583701 0.04 ENST00000527800.1
ENST00000525974.1
ENST00000563369.2
TK2
thymidine kinase 2, mitochondrial
chr10_+_696000 0.04 ENST00000381489.5
PRR26
proline rich 26
chr11_-_104827425 0.04 ENST00000393150.3
CASP4
caspase 4, apoptosis-related cysteine peptidase
chr2_+_87135076 0.04 ENST00000409776.2
RGPD1
RANBP2-like and GRIP domain containing 1
chr9_-_5833027 0.04 ENST00000339450.5
ERMP1
endoplasmic reticulum metallopeptidase 1
chr18_+_61616510 0.04 ENST00000408945.3
HMSD
histocompatibility (minor) serpin domain containing
chr14_-_23292596 0.04 ENST00000554741.1
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr10_+_32873190 0.04 ENST00000375025.4
C10orf68
Homo sapiens coiled-coil domain containing 7 (CCDC7), transcript variant 5, mRNA.
chr2_-_228582709 0.04 ENST00000541617.1
ENST00000409456.2
ENST00000409287.1
ENST00000258403.3
SLC19A3
solute carrier family 19 (thiamine transporter), member 3
chr4_-_186570679 0.04 ENST00000451974.1
SORBS2
sorbin and SH3 domain containing 2
chrX_-_154689596 0.04 ENST00000369444.2
H2AFB3
H2A histone family, member B3
chr15_+_22368478 0.04 ENST00000332663.2
OR4M2
olfactory receptor, family 4, subfamily M, member 2
chr19_-_36304201 0.04 ENST00000301175.3
PRODH2
proline dehydrogenase (oxidase) 2
chr7_+_13141097 0.04 ENST00000411542.1
AC011288.2
AC011288.2
chr15_-_64385981 0.04 ENST00000557835.1
ENST00000380290.3
ENST00000559950.1
FAM96A
family with sequence similarity 96, member A
chr3_-_141747950 0.04 ENST00000497579.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr11_-_26593649 0.04 ENST00000455601.2
MUC15
mucin 15, cell surface associated
chr5_-_149829294 0.04 ENST00000401695.3
RPS14
ribosomal protein S14
chr1_+_196743943 0.04 ENST00000471440.2
ENST00000391985.3
CFHR3
complement factor H-related 3
chr1_+_81771806 0.04 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
LPHN2
latrophilin 2
chr14_-_101295407 0.04 ENST00000596284.1
AL117190.2
AL117190.2
chr7_+_141811539 0.04 ENST00000550469.2
ENST00000477922.3
RP11-1220K2.2
Putative inactive maltase-glucoamylase-like protein LOC93432
chr4_+_89513574 0.04 ENST00000402738.1
ENST00000431413.1
ENST00000422770.1
ENST00000407637.1
HERC3
HECT and RLD domain containing E3 ubiquitin protein ligase 3
chr2_+_11696464 0.04 ENST00000234142.5
GREB1
growth regulation by estrogen in breast cancer 1
chr7_+_23719749 0.04 ENST00000409192.3
ENST00000344962.4
ENST00000409653.1
ENST00000409994.3
FAM221A
family with sequence similarity 221, member A
chr4_+_159131630 0.04 ENST00000504569.1
ENST00000509278.1
ENST00000514558.1
ENST00000503200.1
TMEM144
transmembrane protein 144
chr13_+_111855399 0.04 ENST00000426768.2
ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr7_-_16844611 0.04 ENST00000401412.1
ENST00000419304.2
AGR2
anterior gradient 2
chr1_-_54879140 0.04 ENST00000525990.1
SSBP3
single stranded DNA binding protein 3
chr17_-_6524159 0.04 ENST00000589033.1
KIAA0753
KIAA0753
chr7_-_107883678 0.04 ENST00000417701.1
NRCAM
neuronal cell adhesion molecule
chr17_-_72772462 0.04 ENST00000582870.1
ENST00000581136.1
ENST00000357814.3
ENST00000579218.1
ENST00000583476.1
ENST00000580301.1
ENST00000583757.1
ENST00000582524.1
NAT9
N-acetyltransferase 9 (GCN5-related, putative)
chr1_-_113160826 0.04 ENST00000538187.1
ENST00000369664.1
ST7L
suppression of tumorigenicity 7 like
chr5_+_140762268 0.04 ENST00000518325.1
PCDHGA7
protocadherin gamma subfamily A, 7
chr1_-_211307404 0.04 ENST00000367007.4
KCNH1
potassium voltage-gated channel, subfamily H (eag-related), member 1
chr6_+_26087646 0.04 ENST00000309234.6
HFE
hemochromatosis
chr5_+_140254884 0.04 ENST00000398631.2
PCDHA12
protocadherin alpha 12
chr13_-_46742630 0.04 ENST00000416500.1
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr21_+_33671160 0.04 ENST00000303645.5
MRAP
melanocortin 2 receptor accessory protein
chr2_+_234580525 0.04 ENST00000609637.1
UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A8
chr4_+_155484155 0.04 ENST00000509493.1
FGB
fibrinogen beta chain
chr8_-_143859197 0.03 ENST00000395192.2
LYNX1
Ly6/neurotoxin 1
chr4_-_159080806 0.03 ENST00000590648.1
FAM198B
family with sequence similarity 198, member B
chr12_+_14369524 0.03 ENST00000538329.1
RP11-134N1.2
RP11-134N1.2
chr3_-_145940214 0.03 ENST00000481701.1
PLSCR4
phospholipid scramblase 4
chr2_+_170440844 0.03 ENST00000260970.3
ENST00000433207.1
ENST00000409714.3
ENST00000462903.1
PPIG
peptidylprolyl isomerase G (cyclophilin G)
chr1_+_76251879 0.03 ENST00000535300.1
ENST00000319942.3
RABGGTB
Rab geranylgeranyltransferase, beta subunit
chr4_+_119809984 0.03 ENST00000307142.4
ENST00000448416.2
ENST00000429713.2
SYNPO2
synaptopodin 2
chr12_+_26348429 0.03 ENST00000242729.2
SSPN
sarcospan
chr7_-_55620433 0.03 ENST00000418904.1
VOPP1
vesicular, overexpressed in cancer, prosurvival protein 1
chr4_-_164534657 0.03 ENST00000339875.5
MARCH1
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr10_-_38146482 0.03 ENST00000374648.3
ZNF248
zinc finger protein 248
chr4_-_74486109 0.03 ENST00000395777.2
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr12_-_11287243 0.03 ENST00000539585.1
TAS2R30
taste receptor, type 2, member 30
chr2_+_105050794 0.03 ENST00000429464.1
ENST00000414442.1
ENST00000447380.1
AC013402.2
long intergenic non-protein coding RNA 1102
chr4_+_113568207 0.03 ENST00000511529.1
LARP7
La ribonucleoprotein domain family, member 7
chr2_+_88047606 0.03 ENST00000359481.4
PLGLB2
plasminogen-like B2
chr6_+_34725263 0.03 ENST00000374018.1
ENST00000374017.3
SNRPC
small nuclear ribonucleoprotein polypeptide C
chr6_+_26402517 0.03 ENST00000414912.2
BTN3A1
butyrophilin, subfamily 3, member A1

Network of associatons between targets according to the STRING database.

First level regulatory network of DBX2_HLX

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.1 0.3 GO:0046092 deoxycytidine metabolic process(GO:0046092)
0.0 0.3 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.2 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.1 GO:0002589 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) response to iron ion starvation(GO:1990641)
0.0 0.5 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.1 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.1 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.0 0.1 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 0.1 GO:0060488 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.0 0.1 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.0 0.1 GO:0018032 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
0.0 0.1 GO:0045356 positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0 0.1 GO:0015783 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.0 0.2 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.1 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.0 0.1 GO:0015747 urate transport(GO:0015747)
0.0 0.1 GO:0061151 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.0 0.0 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.0 0.1 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.0 0.0 GO:0097065 anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.0 0.1 GO:0036511 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.0 0.1 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.0 GO:0032661 regulation of interleukin-18 production(GO:0032661)
0.0 0.2 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.1 GO:0034670 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.0 0.0 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.0 0.0 GO:1901420 negative regulation of vitamin D receptor signaling pathway(GO:0070563) negative regulation of response to alcohol(GO:1901420)
0.0 0.1 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.1 GO:0042585 germinal vesicle(GO:0042585)
0.0 0.1 GO:0060187 cell pole(GO:0060187)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.1 GO:0032010 phagolysosome(GO:0032010)
0.0 0.1 GO:1990357 terminal web(GO:1990357)
0.0 0.1 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 0.0 GO:0000806 Y chromosome(GO:0000806)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0031780 melanocortin receptor binding(GO:0031779) corticotropin hormone receptor binding(GO:0031780) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782) type 5 melanocortin receptor binding(GO:0031783) type 1 melanocortin receptor binding(GO:0070996)
0.1 0.3 GO:0019770 IgG receptor activity(GO:0019770)
0.0 0.3 GO:0004797 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.0 0.5 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.2 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.2 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.1 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.1 GO:0008193 tRNA guanylyltransferase activity(GO:0008193)
0.0 0.3 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.1 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0 0.1 GO:0036080 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.0 0.1 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.0 0.1 GO:0016652 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.0 0.1 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.1 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.0 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.0 0.1 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.0 0.0 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.0 0.1 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.1 GO:0042835 BRE binding(GO:0042835)
0.0 0.0 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403) uptake transmembrane transporter activity(GO:0015563)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism