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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for EGR1_EGR4

Z-value: 0.48

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Transcription factors associated with EGR1_EGR4

Gene Symbol Gene ID Gene Info
EGR1
ENSG00000120738.7 early growth response 1
EGR4
ENSG00000135625.6 early growth response 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
EGR1hg19_v2_chr5_+_137801160_1378011790.237.7e-01Click!

Activity profile of EGR1_EGR4 motif

Sorted Z-values of EGR1_EGR4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_61108449 0.32 ENST00000439412.1
ENST00000452343.1
AC010733.4
AC010733.4
chr2_+_191513587 0.26 ENST00000416973.1
ENST00000426601.1
NAB1
NGFI-A binding protein 1 (EGR1 binding protein 1)
chr19_+_47778119 0.25 ENST00000552360.2
PRR24
proline rich 24
chr17_-_77179487 0.25 ENST00000580508.1
RBFOX3
RNA binding protein, fox-1 homolog (C. elegans) 3
chr1_-_9189144 0.22 ENST00000414642.2
GPR157
G protein-coupled receptor 157
chr2_+_220306238 0.22 ENST00000435853.1
SPEG
SPEG complex locus
chr11_+_124609742 0.20 ENST00000284292.6
NRGN
neurogranin (protein kinase C substrate, RC3)
chr16_+_3070313 0.19 ENST00000326577.4
TNFRSF12A
tumor necrosis factor receptor superfamily, member 12A
chr11_+_66624527 0.19 ENST00000393952.3
LRFN4
leucine rich repeat and fibronectin type III domain containing 4
chr5_-_172662197 0.18 ENST00000521848.1
NKX2-5
NK2 homeobox 5
chr17_+_72428266 0.18 ENST00000582473.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr11_+_124609823 0.17 ENST00000412681.2
NRGN
neurogranin (protein kinase C substrate, RC3)
chr1_+_38273988 0.16 ENST00000446260.2
C1orf122
chromosome 1 open reading frame 122
chr1_+_38273818 0.15 ENST00000373042.4
C1orf122
chromosome 1 open reading frame 122
chr9_-_34637806 0.15 ENST00000477726.1
SIGMAR1
sigma non-opioid intracellular receptor 1
chr5_+_421030 0.14 ENST00000506456.1
AHRR
aryl-hydrocarbon receptor repressor
chr5_-_172662230 0.14 ENST00000424406.2
NKX2-5
NK2 homeobox 5
chr19_-_46405861 0.14 ENST00000322217.5
MYPOP
Myb-related transcription factor, partner of profilin
chr16_+_2564254 0.14 ENST00000565223.1
ATP6V0C
ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chr2_+_242498135 0.14 ENST00000318407.3
BOK
BCL2-related ovarian killer
chr22_+_46546406 0.14 ENST00000440343.1
ENST00000415785.1
PPARA
peroxisome proliferator-activated receptor alpha
chr7_+_100860949 0.13 ENST00000305105.2
ZNHIT1
zinc finger, HIT-type containing 1
chr6_+_138188351 0.13 ENST00000421450.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr14_-_21566731 0.13 ENST00000360947.3
ZNF219
zinc finger protein 219
chr22_+_50354104 0.13 ENST00000360612.4
PIM3
pim-3 oncogene
chr1_-_33647267 0.13 ENST00000291416.5
TRIM62
tripartite motif containing 62
chr5_+_175223715 0.13 ENST00000515502.1
CPLX2
complexin 2
chr5_+_133562095 0.12 ENST00000602919.1
CTD-2410N18.3
CTD-2410N18.3
chr19_-_54693401 0.12 ENST00000338624.6
MBOAT7
membrane bound O-acyltransferase domain containing 7
chr5_+_172484377 0.12 ENST00000523161.1
CREBRF
CREB3 regulatory factor
chr15_+_74833518 0.11 ENST00000346246.5
ARID3B
AT rich interactive domain 3B (BRIGHT-like)
chr17_-_7297833 0.11 ENST00000571802.1
ENST00000576201.1
ENST00000573213.1
ENST00000324822.11
TMEM256-PLSCR3
TMEM256-PLSCR3 readthrough (NMD candidate)
chr11_-_64512803 0.11 ENST00000377489.1
ENST00000354024.3
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr2_-_27718052 0.11 ENST00000264703.3
FNDC4
fibronectin type III domain containing 4
chr19_+_589893 0.11 ENST00000251287.2
HCN2
hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chr22_-_30722866 0.11 ENST00000403477.3
TBC1D10A
TBC1 domain family, member 10A
chr14_+_102027688 0.10 ENST00000510508.4
ENST00000359323.3
DIO3
deiodinase, iodothyronine, type III
chr19_+_36132631 0.10 ENST00000379026.2
ENST00000379023.4
ENST00000402764.2
ENST00000479824.1
ETV2
ets variant 2
chr9_+_34652164 0.10 ENST00000441545.2
ENST00000553620.1
IL11RA
interleukin 11 receptor, alpha
chr1_+_156698743 0.10 ENST00000524343.1
RRNAD1
ribosomal RNA adenine dimethylase domain containing 1
chr19_-_14201507 0.10 ENST00000533683.2
SAMD1
sterile alpha motif domain containing 1
chr11_-_506739 0.10 ENST00000529306.1
ENST00000438658.2
ENST00000527485.1
ENST00000397615.2
ENST00000397614.1
RNH1
ribonuclease/angiogenin inhibitor 1
chr17_-_42402138 0.10 ENST00000592857.1
ENST00000586016.1
ENST00000590194.1
ENST00000377095.5
ENST00000588049.1
ENST00000586633.1
ENST00000537904.2
ENST00000585636.1
ENST00000585523.1
ENST00000225308.8
SLC25A39
solute carrier family 25, member 39
chr20_+_49348081 0.10 ENST00000371610.2
PARD6B
par-6 family cell polarity regulator beta
chr1_-_94312706 0.10 ENST00000370244.1
BCAR3
breast cancer anti-estrogen resistance 3
chr1_+_155051305 0.10 ENST00000368408.3
EFNA3
ephrin-A3
chr20_-_31172598 0.10 ENST00000201961.2
C20orf112
chromosome 20 open reading frame 112
chr4_+_103422499 0.10 ENST00000511926.1
ENST00000507079.1
NFKB1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr16_+_3014269 0.10 ENST00000575885.1
ENST00000571007.1
ENST00000319500.6
KREMEN2
kringle containing transmembrane protein 2
chr19_+_49617609 0.10 ENST00000221459.2
ENST00000486217.2
LIN7B
lin-7 homolog B (C. elegans)
chr10_+_49514698 0.09 ENST00000432379.1
ENST00000429041.1
ENST00000374189.1
MAPK8
mitogen-activated protein kinase 8
chr1_+_161494036 0.09 ENST00000309758.4
HSPA6
heat shock 70kDa protein 6 (HSP70B')
chr6_+_11537910 0.09 ENST00000543875.1
TMEM170B
transmembrane protein 170B
chr4_-_90758227 0.09 ENST00000506691.1
ENST00000394986.1
ENST00000506244.1
ENST00000394989.2
ENST00000394991.3
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr17_+_54671047 0.09 ENST00000332822.4
NOG
noggin
chr8_+_145064233 0.09 ENST00000529301.1
ENST00000395068.4
GRINA
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr18_+_3449821 0.09 ENST00000407501.2
ENST00000405385.3
ENST00000546979.1
TGIF1
TGFB-induced factor homeobox 1
chr19_-_54693521 0.09 ENST00000391754.1
ENST00000245615.1
ENST00000431666.2
MBOAT7
membrane bound O-acyltransferase domain containing 7
chrX_+_71996972 0.09 ENST00000334036.5
DMRTC1B
DMRT-like family C1B
chrX_-_47479246 0.09 ENST00000295987.7
ENST00000340666.4
SYN1
synapsin I
chr20_+_35202909 0.09 ENST00000558530.1
ENST00000558028.1
ENST00000560025.1
TGIF2-C20orf24
TGIF2
TGIF2-C20orf24 readthrough
TGFB-induced factor homeobox 2
chr2_-_128145498 0.09 ENST00000409179.2
MAP3K2
mitogen-activated protein kinase kinase kinase 2
chr19_-_1863567 0.09 ENST00000250916.4
KLF16
Kruppel-like factor 16
chr14_-_20922960 0.09 ENST00000553640.1
ENST00000488532.2
OSGEP
O-sialoglycoprotein endopeptidase
chr16_+_30194916 0.09 ENST00000570045.1
ENST00000565497.1
ENST00000570244.1
CORO1A
coronin, actin binding protein, 1A
chr19_-_663277 0.09 ENST00000292363.5
RNF126
ring finger protein 126
chrX_-_23926004 0.08 ENST00000379226.4
ENST00000379220.3
APOO
apolipoprotein O
chr9_-_140196703 0.08 ENST00000356628.2
NRARP
NOTCH-regulated ankyrin repeat protein
chrX_+_117957741 0.08 ENST00000310164.2
ZCCHC12
zinc finger, CCHC domain containing 12
chr1_+_65886326 0.08 ENST00000371059.3
ENST00000371060.3
ENST00000349533.6
ENST00000406510.3
LEPR
leptin receptor
chr5_-_101632153 0.08 ENST00000310954.6
SLCO4C1
solute carrier organic anion transporter family, member 4C1
chr19_+_10531150 0.08 ENST00000352831.6
PDE4A
phosphodiesterase 4A, cAMP-specific
chr14_-_23822080 0.08 ENST00000397267.1
ENST00000354772.3
SLC22A17
solute carrier family 22, member 17
chr11_-_507184 0.08 ENST00000533410.1
ENST00000354420.2
ENST00000397604.3
ENST00000531149.1
ENST00000356187.5
RNH1
ribonuclease/angiogenin inhibitor 1
chr10_+_6625605 0.08 ENST00000414894.1
ENST00000449648.1
PRKCQ-AS1
PRKCQ antisense RNA 1
chr4_-_82393009 0.08 ENST00000436139.2
RASGEF1B
RasGEF domain family, member 1B
chr19_-_54693146 0.08 ENST00000414665.1
ENST00000453320.1
MBOAT7
membrane bound O-acyltransferase domain containing 7
chr16_-_2264779 0.08 ENST00000333503.7
PGP
phosphoglycolate phosphatase
chr3_-_135916073 0.08 ENST00000481989.1
MSL2
male-specific lethal 2 homolog (Drosophila)
chr19_-_5567842 0.08 ENST00000587632.1
TINCR
tissue differentiation-inducing non-protein coding RNA
chr17_+_77751931 0.08 ENST00000310942.4
ENST00000269399.5
CBX2
chromobox homolog 2
chr19_+_50879705 0.08 ENST00000598168.1
ENST00000411902.2
ENST00000253727.5
ENST00000597790.1
ENST00000597130.1
ENST00000599105.1
NR1H2
nuclear receptor subfamily 1, group H, member 2
chr17_+_46185111 0.07 ENST00000582104.1
ENST00000584335.1
SNX11
sorting nexin 11
chr11_+_46403303 0.07 ENST00000407067.1
ENST00000395565.1
MDK
midkine (neurite growth-promoting factor 2)
chr22_-_30722912 0.07 ENST00000215790.7
TBC1D10A
TBC1 domain family, member 10A
chr20_+_48429356 0.07 ENST00000361573.2
ENST00000541138.1
ENST00000539601.1
SLC9A8
solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
chr19_-_36523529 0.07 ENST00000593074.1
CLIP3
CAP-GLY domain containing linker protein 3
chr6_+_144471643 0.07 ENST00000367568.4
STX11
syntaxin 11
chr12_-_56223363 0.07 ENST00000546957.1
DNAJC14
DnaJ (Hsp40) homolog, subfamily C, member 14
chr17_+_72772621 0.07 ENST00000335464.5
ENST00000417024.2
ENST00000578764.1
ENST00000582773.1
ENST00000582330.1
TMEM104
transmembrane protein 104
chr3_-_194207388 0.07 ENST00000457986.1
ATP13A3
ATPase type 13A3
chr17_-_7297519 0.07 ENST00000576362.1
ENST00000571078.1
TMEM256-PLSCR3
TMEM256-PLSCR3 readthrough (NMD candidate)
chr17_+_72428218 0.07 ENST00000392628.2
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr18_-_53255766 0.07 ENST00000566286.1
ENST00000564999.1
ENST00000566279.1
ENST00000354452.3
ENST00000356073.4
TCF4
transcription factor 4
chr19_-_663171 0.07 ENST00000606896.1
ENST00000589762.2
RNF126
ring finger protein 126
chr7_+_128502895 0.07 ENST00000492758.1
ATP6V1F
ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F
chr22_+_31090793 0.07 ENST00000332585.6
ENST00000382310.3
ENST00000446658.2
OSBP2
oxysterol binding protein 2
chr7_-_5569588 0.07 ENST00000417101.1
ACTB
actin, beta
chr5_-_176923846 0.07 ENST00000506537.1
PDLIM7
PDZ and LIM domain 7 (enigma)
chr11_+_66045634 0.07 ENST00000528852.1
ENST00000311445.6
CNIH2
cornichon family AMPA receptor auxiliary protein 2
chr1_-_35395178 0.07 ENST00000373347.1
DLGAP3
discs, large (Drosophila) homolog-associated protein 3
chr11_-_66103932 0.07 ENST00000311320.4
RIN1
Ras and Rab interactor 1
chr1_+_155051379 0.07 ENST00000418360.2
EFNA3
ephrin-A3
chr19_+_35634146 0.07 ENST00000586063.1
ENST00000270310.2
ENST00000588265.1
FXYD7
FXYD domain containing ion transport regulator 7
chr16_+_3070356 0.07 ENST00000341627.5
ENST00000575124.1
ENST00000575836.1
TNFRSF12A
tumor necrosis factor receptor superfamily, member 12A
chr5_+_176853702 0.07 ENST00000507633.1
ENST00000393576.3
ENST00000355958.5
ENST00000528793.1
ENST00000512684.1
GRK6
G protein-coupled receptor kinase 6
chr2_-_38830030 0.07 ENST00000410076.1
HNRNPLL
heterogeneous nuclear ribonucleoprotein L-like
chr1_-_156786634 0.07 ENST00000392306.2
ENST00000368199.3
SH2D2A
SH2 domain containing 2A
chr5_+_176853669 0.07 ENST00000355472.5
GRK6
G protein-coupled receptor kinase 6
chr16_-_66959429 0.07 ENST00000420652.1
ENST00000299759.6
RRAD
Ras-related associated with diabetes
chr11_-_64512273 0.06 ENST00000377497.3
ENST00000377487.1
ENST00000430645.1
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr16_-_2185899 0.06 ENST00000262304.4
ENST00000423118.1
PKD1
polycystic kidney disease 1 (autosomal dominant)
chr16_+_29823427 0.06 ENST00000358758.7
ENST00000567659.1
ENST00000572820.1
PRRT2
proline-rich transmembrane protein 2
chr17_-_17494972 0.06 ENST00000435340.2
ENST00000255389.5
ENST00000395781.2
PEMT
phosphatidylethanolamine N-methyltransferase
chr11_-_118966167 0.06 ENST00000530167.1
H2AFX
H2A histone family, member X
chr1_+_156698708 0.06 ENST00000519086.1
RRNAD1
ribosomal RNA adenine dimethylase domain containing 1
chr11_-_64014379 0.06 ENST00000309318.3
PPP1R14B
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr1_+_156698234 0.06 ENST00000368218.4
ENST00000368216.4
RRNAD1
ribosomal RNA adenine dimethylase domain containing 1
chr17_-_41623716 0.06 ENST00000319349.5
ETV4
ets variant 4
chr19_+_14544099 0.06 ENST00000242783.6
ENST00000586557.1
ENST00000590097.1
PKN1
protein kinase N1
chr8_+_144821557 0.06 ENST00000534398.1
FAM83H-AS1
FAM83H antisense RNA 1 (head to head)
chr1_+_35734616 0.06 ENST00000441447.1
ZMYM4
zinc finger, MYM-type 4
chr16_-_29910365 0.06 ENST00000346932.5
ENST00000350527.3
ENST00000537485.1
ENST00000568380.1
SEZ6L2
seizure related 6 homolog (mouse)-like 2
chr17_+_75369400 0.06 ENST00000590059.1
SEPT9
septin 9
chr6_+_12012536 0.06 ENST00000379388.2
HIVEP1
human immunodeficiency virus type I enhancer binding protein 1
chr15_-_71146347 0.06 ENST00000559140.2
LARP6
La ribonucleoprotein domain family, member 6
chr9_-_130742792 0.06 ENST00000373095.1
FAM102A
family with sequence similarity 102, member A
chr16_+_28834303 0.06 ENST00000340394.8
ENST00000325215.6
ENST00000395547.2
ENST00000336783.4
ENST00000382686.4
ENST00000564304.1
ATXN2L
ataxin 2-like
chr5_+_149109825 0.06 ENST00000360453.4
ENST00000394320.3
ENST00000309241.5
PPARGC1B
peroxisome proliferator-activated receptor gamma, coactivator 1 beta
chr22_+_38597889 0.06 ENST00000338483.2
ENST00000538320.1
ENST00000538999.1
ENST00000441709.1
MAFF
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
chr7_+_27282319 0.06 ENST00000222761.3
EVX1
even-skipped homeobox 1
chr8_-_145911188 0.06 ENST00000540274.1
ARHGAP39
Rho GTPase activating protein 39
chr7_-_559853 0.06 ENST00000405692.2
PDGFA
platelet-derived growth factor alpha polypeptide
chr17_-_79995553 0.06 ENST00000581584.1
ENST00000577712.1
ENST00000582900.1
ENST00000579155.1
ENST00000306869.2
DCXR
dicarbonyl/L-xylulose reductase
chr18_+_3449695 0.06 ENST00000343820.5
TGIF1
TGFB-induced factor homeobox 1
chr21_+_44394742 0.06 ENST00000432907.2
PKNOX1
PBX/knotted 1 homeobox 1
chr12_+_107349606 0.06 ENST00000547242.1
ENST00000551489.1
ENST00000550344.1
C12orf23
chromosome 12 open reading frame 23
chrX_+_153237740 0.06 ENST00000369982.4
TMEM187
transmembrane protein 187
chr22_-_24181174 0.06 ENST00000318109.7
ENST00000406855.3
ENST00000404056.1
ENST00000476077.1
DERL3
derlin 3
chr19_-_9929708 0.06 ENST00000247977.4
ENST00000590277.1
ENST00000588922.1
ENST00000589626.1
ENST00000592067.1
ENST00000586469.1
FBXL12
F-box and leucine-rich repeat protein 12
chr19_+_676385 0.06 ENST00000166139.4
FSTL3
follistatin-like 3 (secreted glycoprotein)
chr12_-_49582593 0.06 ENST00000295766.5
TUBA1A
tubulin, alpha 1a
chr3_+_75721428 0.05 ENST00000463183.1
LINC00960
long intergenic non-protein coding RNA 960
chr6_+_134274322 0.05 ENST00000367871.1
ENST00000237264.4
TBPL1
TBP-like 1
chr16_+_2933209 0.05 ENST00000293981.6
FLYWCH2
FLYWCH family member 2
chr1_-_15850676 0.05 ENST00000440484.1
ENST00000333868.5
CASP9
caspase 9, apoptosis-related cysteine peptidase
chr19_+_54412517 0.05 ENST00000391767.1
CACNG7
calcium channel, voltage-dependent, gamma subunit 7
chr11_+_46403194 0.05 ENST00000395569.4
ENST00000395566.4
MDK
midkine (neurite growth-promoting factor 2)
chr14_-_23770683 0.05 ENST00000561437.1
ENST00000559942.1
ENST00000560913.1
ENST00000559314.1
ENST00000558058.1
PPP1R3E
protein phosphatase 1, regulatory subunit 3E
chr8_+_128747661 0.05 ENST00000259523.6
MYC
v-myc avian myelocytomatosis viral oncogene homolog
chr11_+_46402583 0.05 ENST00000359803.3
MDK
midkine (neurite growth-promoting factor 2)
chr7_-_100860851 0.05 ENST00000223127.3
PLOD3
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chr19_-_36505098 0.05 ENST00000252984.7
ENST00000486389.1
ENST00000378875.3
ENST00000485128.1
ALKBH6
alkB, alkylation repair homolog 6 (E. coli)
chrX_+_37545012 0.05 ENST00000378616.3
XK
X-linked Kx blood group (McLeod syndrome)
chr11_-_64511575 0.05 ENST00000431822.1
ENST00000377486.3
ENST00000394432.3
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr11_+_67070919 0.05 ENST00000308127.4
ENST00000308298.7
SSH3
slingshot protein phosphatase 3
chr8_-_145331153 0.05 ENST00000377412.4
KM-PA-2
KM-PA-2 protein; Uncharacterized protein
chr12_+_56661033 0.05 ENST00000433805.2
COQ10A
coenzyme Q10 homolog A (S. cerevisiae)
chr5_+_63461642 0.05 ENST00000296615.6
ENST00000381081.2
ENST00000389100.4
RNF180
ring finger protein 180
chr3_+_88108381 0.05 ENST00000473136.1
RP11-159G9.5
Uncharacterized protein
chr1_-_182573514 0.05 ENST00000367558.5
RGS16
regulator of G-protein signaling 16
chr11_-_123525289 0.05 ENST00000392770.2
ENST00000299333.3
ENST00000530277.1
SCN3B
sodium channel, voltage-gated, type III, beta subunit
chr19_-_40724246 0.05 ENST00000311308.6
TTC9B
tetratricopeptide repeat domain 9B
chr3_-_45267760 0.05 ENST00000503771.1
TMEM158
transmembrane protein 158 (gene/pseudogene)
chr2_+_191208601 0.05 ENST00000413239.1
ENST00000431594.1
ENST00000444194.1
INPP1
inositol polyphosphate-1-phosphatase
chr1_-_6052463 0.05 ENST00000378156.4
NPHP4
nephronophthisis 4
chr5_+_149865838 0.05 ENST00000519157.1
NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr11_+_66610883 0.05 ENST00000309657.3
ENST00000524506.1
RCE1
Ras converting CAAX endopeptidase 1
chr4_+_109571800 0.05 ENST00000512478.2
OSTC
oligosaccharyltransferase complex subunit (non-catalytic)
chr1_+_6673745 0.05 ENST00000377648.4
PHF13
PHD finger protein 13
chr9_+_74764340 0.05 ENST00000376986.1
ENST00000358399.3
GDA
guanine deaminase
chr7_+_43966018 0.05 ENST00000222402.3
ENST00000446008.1
ENST00000394798.4
UBE2D4
ubiquitin-conjugating enzyme E2D 4 (putative)
chr5_+_139028510 0.05 ENST00000502336.1
ENST00000520967.1
ENST00000511048.1
CXXC5
CXXC finger protein 5
chr17_-_18945798 0.05 ENST00000395635.1
GRAP
GRB2-related adaptor protein
chr11_-_66104237 0.05 ENST00000530056.1
RIN1
Ras and Rab interactor 1
chr17_-_72772462 0.05 ENST00000582870.1
ENST00000581136.1
ENST00000357814.3
ENST00000579218.1
ENST00000583476.1
ENST00000580301.1
ENST00000583757.1
ENST00000582524.1
NAT9
N-acetyltransferase 9 (GCN5-related, putative)
chr9_-_34637718 0.05 ENST00000378892.1
ENST00000277010.4
SIGMAR1
sigma non-opioid intracellular receptor 1
chr16_+_28986085 0.05 ENST00000565975.1
ENST00000311008.11
ENST00000323081.8
ENST00000334536.8
SPNS1
spinster homolog 1 (Drosophila)
chr20_+_48429233 0.05 ENST00000417961.1
SLC9A8
solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
chr19_-_55691614 0.05 ENST00000592470.1
ENST00000354308.3
SYT5
synaptotagmin V
chr17_-_4710288 0.05 ENST00000571067.1
RP11-81A22.5
RP11-81A22.5
chr19_+_7985880 0.05 ENST00000597584.1
SNAPC2
small nuclear RNA activating complex, polypeptide 2, 45kDa
chr20_-_62258394 0.05 ENST00000370077.1
GMEB2
glucocorticoid modulatory element binding protein 2
chr19_-_55919087 0.05 ENST00000587845.1
ENST00000589978.1
ENST00000264552.9
UBE2S
ubiquitin-conjugating enzyme E2S
chr8_-_145060593 0.05 ENST00000313059.5
ENST00000524918.1
ENST00000313028.7
ENST00000525773.1
PARP10
poly (ADP-ribose) polymerase family, member 10
chrX_+_16964794 0.05 ENST00000357277.3
REPS2
RALBP1 associated Eps domain containing 2
chr11_-_77899634 0.05 ENST00000526208.1
ENST00000529350.1
ENST00000530018.1
ENST00000528776.1
KCTD21
potassium channel tetramerization domain containing 21
chr20_+_36531499 0.05 ENST00000373458.3
ENST00000373461.4
ENST00000373459.4
VSTM2L
V-set and transmembrane domain containing 2 like
chr7_+_116593953 0.05 ENST00000397750.3
ST7-OT4
ST7 overlapping transcript 4
chr22_-_24110063 0.05 ENST00000520222.1
ENST00000401675.3
CHCHD10
coiled-coil-helix-coiled-coil-helix domain containing 10
chr19_-_45953983 0.05 ENST00000592083.1
ERCC1
excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr1_+_32671236 0.05 ENST00000537469.1
ENST00000291358.6
IQCC
IQ motif containing C
chr19_+_1275917 0.05 ENST00000469144.1
C19orf24
chromosome 19 open reading frame 24
chr7_+_100199800 0.05 ENST00000223061.5
PCOLCE
procollagen C-endopeptidase enhancer
chr12_-_53625958 0.05 ENST00000327550.3
ENST00000546717.1
ENST00000425354.2
ENST00000394426.1
RARG
retinoic acid receptor, gamma
chr12_+_1099675 0.05 ENST00000545318.2
ERC1
ELKS/RAB6-interacting/CAST family member 1
chr16_+_2563871 0.05 ENST00000330398.4
ENST00000568562.1
ENST00000569317.1
ATP6V0C
ATP6C
ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
Uncharacterized protein
chr19_+_39897453 0.05 ENST00000597629.1
ENST00000248673.3
ENST00000594045.1
ENST00000594442.1
ZFP36
ZFP36 ring finger protein
chr3_-_49907323 0.05 ENST00000296471.7
ENST00000488336.1
ENST00000467248.1
ENST00000466940.1
ENST00000463537.1
ENST00000480398.2
CAMKV
CaM kinase-like vesicle-associated
chr19_+_19303572 0.05 ENST00000407360.3
ENST00000540981.1
RFXANK
regulatory factor X-associated ankyrin-containing protein

Network of associatons between targets according to the STRING database.

First level regulatory network of EGR1_EGR4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0003168 Purkinje myocyte differentiation(GO:0003168) cardiac pacemaker cell fate commitment(GO:0060927) atrioventricular node cell fate commitment(GO:0060929)
0.0 0.1 GO:0072361 regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter(GO:0072361)
0.0 0.1 GO:2000349 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573) negative regulation of CD40 signaling pathway(GO:2000349)
0.0 0.1 GO:0060796 regulation of transcription involved in primary germ layer cell fate commitment(GO:0060796)
0.0 0.0 GO:0071505 response to mycophenolic acid(GO:0071505) cellular response to mycophenolic acid(GO:0071506)
0.0 0.1 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.1 GO:0045083 negative regulation of interleukin-12 biosynthetic process(GO:0045083)
0.0 0.2 GO:0001839 neural plate morphogenesis(GO:0001839)
0.0 0.1 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.1 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.0 0.2 GO:0030421 defecation(GO:0030421)
0.0 0.1 GO:0097360 chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
0.0 0.1 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.0 0.3 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.1 GO:0090108 positive regulation of high-density lipoprotein particle assembly(GO:0090108) positive regulation of pancreatic juice secretion(GO:0090187) positive regulation of secretion of lysosomal enzymes(GO:0090340)
0.0 0.1 GO:2000656 regulation of apolipoprotein binding(GO:2000656) negative regulation of apolipoprotein binding(GO:2000657)
0.0 0.1 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.1 GO:0071629 cytoplasm-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071629)
0.0 0.1 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.1 GO:0090095 regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.0 0.1 GO:0035674 tricarboxylic acid transmembrane transport(GO:0035674)
0.0 0.1 GO:0051585 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.0 0.1 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.0 0.1 GO:0042732 D-xylose metabolic process(GO:0042732)
0.0 0.2 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.1 GO:0098507 polynucleotide 5' dephosphorylation(GO:0098507)
0.0 0.1 GO:0061341 chemoattraction of serotonergic neuron axon(GO:0036517) non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346) planar cell polarity pathway involved in outflow tract morphogenesis(GO:0061347) planar cell polarity pathway involved in ventricular septum morphogenesis(GO:0061348) planar cell polarity pathway involved in cardiac right atrium morphogenesis(GO:0061349) planar cell polarity pathway involved in cardiac muscle tissue morphogenesis(GO:0061350) planar cell polarity pathway involved in pericardium morphogenesis(GO:0061354) chemoattraction of axon(GO:0061642) negative regulation of cell proliferation in midbrain(GO:1904934) planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation(GO:1904955)
0.0 0.1 GO:0006147 guanine catabolic process(GO:0006147)
0.0 0.1 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.0 0.0 GO:0006816 calcium ion transport(GO:0006816)
0.0 0.1 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085) regulation of polynucleotide adenylyltransferase activity(GO:1904245)
0.0 0.1 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.1 GO:0032796 uropod organization(GO:0032796)
0.0 0.1 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.0 0.0 GO:0071586 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.0 0.1 GO:0072287 metanephric distal tubule morphogenesis(GO:0072287)
0.0 0.1 GO:0010512 negative regulation of phosphatidylinositol biosynthetic process(GO:0010512)
0.0 0.0 GO:0042137 sequestering of neurotransmitter(GO:0042137)
0.0 0.1 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.0 0.2 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.0 0.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.0 GO:0003274 endocardial cushion fusion(GO:0003274)
0.0 0.1 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0 0.2 GO:0060019 radial glial cell differentiation(GO:0060019)
0.0 0.3 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.0 0.0 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.0 0.1 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 0.1 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.0 0.1 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.1 GO:0046549 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.2 GO:1905247 positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.0 0.0 GO:1901656 glycoside transport(GO:1901656)
0.0 0.0 GO:0070266 necroptotic process(GO:0070266)
0.0 0.0 GO:1904897 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.0 0.1 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.0 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.0 0.0 GO:0002513 tolerance induction to self antigen(GO:0002513)
0.0 0.0 GO:0019417 sulfur oxidation(GO:0019417)
0.0 0.0 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.0 0.0 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.0 0.0 GO:0071529 cementum mineralization(GO:0071529)
0.0 0.1 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0 0.1 GO:0097091 synaptic vesicle clustering(GO:0097091)
0.0 0.1 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.1 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.0 0.1 GO:0033962 regulation of cytoplasmic mRNA processing body assembly(GO:0010603) cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 0.1 GO:0006235 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.0 0.1 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.0 0.2 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.1 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.0 0.0 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.0 0.3 GO:1900273 positive regulation of long-term synaptic potentiation(GO:1900273)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0034753 nuclear aryl hydrocarbon receptor complex(GO:0034753)
0.0 0.2 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.0 0.1 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.1 GO:0043293 apoptosome(GO:0043293)
0.0 0.2 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.3 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.1 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.0 0.0 GO:0002139 stereocilia coupling link(GO:0002139)
0.0 0.1 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.1 GO:0061617 MICOS complex(GO:0061617)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0010736 serum response element binding(GO:0010736)
0.0 0.1 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.0 0.2 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 0.1 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.1 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.0 0.1 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.1 GO:0001133 RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding(GO:0001133)
0.0 0.2 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.1 GO:0043208 glycosphingolipid binding(GO:0043208) ceramide binding(GO:0097001)
0.0 0.1 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.1 GO:0052829 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829)
0.0 0.1 GO:0004584 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity(GO:0004584)
0.0 0.1 GO:0004608 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.0 0.1 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.0 0.1 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.0 0.3 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 0.1 GO:1902379 receptor tyrosine kinase-like orphan receptor binding(GO:0005115) chemoattractant activity involved in axon guidance(GO:1902379)
0.0 0.1 GO:0008892 guanine deaminase activity(GO:0008892)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.2 GO:0008428 ribonuclease inhibitor activity(GO:0008428)
0.0 0.1 GO:0004376 glycolipid mannosyltransferase activity(GO:0004376)
0.0 0.1 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.0 0.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.2 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.0 GO:0047025 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.0 0.0 GO:0004960 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.0 0.0 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.1 GO:0015137 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 0.1 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.1 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 0.1 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI