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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for ESRRB_ESRRG

Z-value: 0.84

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Transcription factors associated with ESRRB_ESRRG

Gene Symbol Gene ID Gene Info
ENSG00000119715.10 estrogen related receptor beta
ENSG00000196482.12 estrogen related receptor gamma

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ESRRBhg19_v2_chr14_+_76776957_767770610.891.1e-01Click!
ESRRGhg19_v2_chr1_-_217311090_217311097-0.851.5e-01Click!

Activity profile of ESRRB_ESRRG motif

Sorted Z-values of ESRRB_ESRRG motif

Promoter Log-likelihood Transcript Gene Gene Info
chrX_+_109602039 0.92 ENST00000520821.1
retrotransposon gag domain containing 1
chr11_+_66624527 0.76 ENST00000393952.3
leucine rich repeat and fibronectin type III domain containing 4
chr11_-_790060 0.71 ENST00000330106.4
cell cycle exit and neuronal differentiation 1
chr16_+_776936 0.69 ENST00000549114.1
ENST00000341413.4
ENST00000562187.1
ENST00000564537.1
hydroxyacylglutathione hydrolase-like
chr11_-_63993601 0.64 ENST00000545812.1
ENST00000394547.3
ENST00000317459.6
tRNA phosphotransferase 1
chr14_-_103987679 0.57 ENST00000553610.1
creatine kinase, brain
chr11_-_118272610 0.56 ENST00000534438.1
Uncharacterized protein
chr11_+_67798114 0.55 ENST00000453471.2
ENST00000528492.1
ENST00000526339.1
ENST00000525419.1
NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
chr16_+_777739 0.52 ENST00000563792.1
hydroxyacylglutathione hydrolase-like
chr11_-_63993690 0.52 ENST00000394546.2
ENST00000541278.1
tRNA phosphotransferase 1
chr16_+_691792 0.51 ENST00000307650.4
family with sequence similarity 195, member A
chr7_-_150777920 0.47 ENST00000353841.2
ENST00000297532.6
Fas-activated serine/threonine kinase
chr11_-_1783633 0.42 ENST00000367196.3
cathepsin D
chr18_-_56985776 0.41 ENST00000587244.1
complexin 4
chr11_-_47470682 0.39 ENST00000529341.1
ENST00000352508.3
receptor-associated protein of the synapse
chr10_-_76995675 0.39 ENST00000469299.1
catechol-O-methyltransferase domain containing 1
chr10_-_76995769 0.38 ENST00000372538.3
catechol-O-methyltransferase domain containing 1
chr16_+_777118 0.34 ENST00000562141.1
hydroxyacylglutathione hydrolase-like
chr11_+_67798363 0.34 ENST00000525628.1
NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
chr2_-_176046391 0.34 ENST00000392541.3
ENST00000409194.1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
chr10_-_10504285 0.34 ENST00000602311.1
RP11-271F18.4
chr22_+_46546406 0.33 ENST00000440343.1
ENST00000415785.1
peroxisome proliferator-activated receptor alpha
chr22_+_29702996 0.33 ENST00000406549.3
ENST00000360113.2
ENST00000341313.6
ENST00000403764.1
ENST00000471961.1
ENST00000407854.1
growth arrest-specific 2 like 1
chr15_+_67813406 0.33 ENST00000342683.4
chromosome 15 open reading frame 61
chr7_-_150777874 0.33 ENST00000540185.1
Fas-activated serine/threonine kinase
chr7_-_150777949 0.32 ENST00000482571.1
Fas-activated serine/threonine kinase
chr15_-_76352069 0.32 ENST00000305435.10
ENST00000563910.1
neuregulin 4
chr12_-_111358372 0.32 ENST00000548438.1
ENST00000228841.8
myosin, light chain 2, regulatory, cardiac, slow
chr22_+_30115986 0.31 ENST00000216144.3
calcium binding protein 7
chr1_+_155179012 0.31 ENST00000609421.1
metaxin 1
chr12_+_6644443 0.30 ENST00000396858.1
glyceraldehyde-3-phosphate dehydrogenase
chr1_+_16083154 0.30 ENST00000375771.1
filamin binding LIM protein 1
chr17_+_73455788 0.29 ENST00000581519.1
KIAA0195
chr19_+_41699103 0.28 ENST00000597754.1
cytochrome P450, family 2, subfamily S, polypeptide 1
chr12_-_57039739 0.27 ENST00000552959.1
ENST00000551020.1
ENST00000553007.2
ENST00000552919.1
ENST00000552104.1
ENST00000262030.3
ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
chr8_-_145752390 0.27 ENST00000529415.2
ENST00000533758.1
leucine rich repeat containing 24
chr11_+_86667117 0.25 ENST00000531827.1
RP11-736K20.6
chr20_-_3748363 0.25 ENST00000217195.8
chromosome 20 open reading frame 27
chr8_+_145149930 0.25 ENST00000318911.4
cytochrome c-1
chr2_-_198364552 0.25 ENST00000439605.1
ENST00000418022.1
heat shock 60kDa protein 1 (chaperonin)
chr15_-_81616446 0.25 ENST00000302824.6
StAR-related lipid transfer (START) domain containing 5
chr22_-_24110063 0.25 ENST00000520222.1
ENST00000401675.3
coiled-coil-helix-coiled-coil-helix domain containing 10
chr1_+_207262881 0.25 ENST00000451804.2
complement component 4 binding protein, beta
chr1_-_149889382 0.25 ENST00000369145.1
ENST00000369146.3
synaptic vesicle glycoprotein 2A
chr10_+_112257596 0.24 ENST00000369583.3
dual specificity phosphatase 5
chr19_-_36019123 0.24 ENST00000588674.1
ENST00000452271.2
ENST00000518157.1
suprabasin
chr1_-_207119738 0.24 ENST00000356495.4
polymeric immunoglobulin receptor
chr17_+_79679369 0.24 ENST00000350690.5
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
chr19_+_589893 0.23 ENST00000251287.2
hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chr1_-_235116495 0.23 ENST00000549744.1
RP11-443B7.3
chr5_+_175085033 0.23 ENST00000377291.2
histamine receptor H2
chr11_+_66059339 0.23 ENST00000327259.4
transmembrane protein 151A
chr17_-_1553346 0.22 ENST00000301336.6
Rab interacting lysosomal protein
chr12_+_121163538 0.22 ENST00000242592.4
acyl-CoA dehydrogenase, C-2 to C-3 short chain
chr22_+_30821732 0.21 ENST00000355143.4
mitochondrial fission process 1
chr1_+_36024107 0.21 ENST00000437806.1
neurochondrin
chr11_+_22646739 0.21 ENST00000428556.2
AC103801.2
chr14_-_102976135 0.21 ENST00000560748.1
ankyrin repeat domain 9
chr19_-_15236562 0.21 ENST00000263383.3
ilvB (bacterial acetolactate synthase)-like
chr6_+_89790490 0.21 ENST00000336032.3
proline-rich nuclear receptor coactivator 1
chr15_+_67814008 0.21 ENST00000557807.1
chromosome 15 open reading frame 61
chr22_+_50354104 0.20 ENST00000360612.4
pim-3 oncogene
chr16_+_28875126 0.20 ENST00000359285.5
ENST00000538342.1
SH2B adaptor protein 1
chr20_-_3748416 0.20 ENST00000399672.1
chromosome 20 open reading frame 27
chr17_-_79838860 0.20 ENST00000582866.1
RP11-498C9.15
chr16_+_28874860 0.20 ENST00000545570.1
SH2B adaptor protein 1
chr12_+_58176525 0.19 ENST00000543727.1
ENST00000540550.1
ENST00000323833.8
ENST00000350762.5
ENST00000550559.1
ENST00000548851.1
ENST00000434359.1
ENST00000457189.1
Ts translation elongation factor, mitochondrial
chr17_+_79679299 0.19 ENST00000331531.5
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
chr3_-_179322416 0.19 ENST00000259038.2
mitochondrial ribosomal protein L47
chr19_+_38307999 0.19 ENST00000589653.1
ENST00000590433.1
CTD-2554C21.2
chr17_-_65235916 0.19 ENST00000579861.1
helicase with zinc finger
chr12_+_6643676 0.19 ENST00000396856.1
ENST00000396861.1
glyceraldehyde-3-phosphate dehydrogenase
chr16_+_30937213 0.19 ENST00000427128.1
F-box and leucine-rich repeat protein 19
chr5_+_111964133 0.18 ENST00000508879.1
ENST00000507565.1
RP11-159K7.2
chr6_-_26285737 0.18 ENST00000377727.1
ENST00000289352.1
histone cluster 1, H4h
chr16_-_29874211 0.18 ENST00000563415.1
CDP-diacylglycerol--inositol 3-phosphatidyltransferase
chr19_+_2249308 0.18 ENST00000592877.1
ENST00000221496.4
anti-Mullerian hormone
chr6_-_33548006 0.18 ENST00000374467.3
BCL2-antagonist/killer 1
chr1_+_16083098 0.18 ENST00000496928.2
ENST00000508310.1
filamin binding LIM protein 1
chr1_+_16083123 0.18 ENST00000510393.1
ENST00000430076.1
filamin binding LIM protein 1
chr19_-_3062465 0.18 ENST00000327141.4
amino-terminal enhancer of split
chr22_-_30960876 0.18 ENST00000401975.1
ENST00000428682.1
ENST00000423299.1
galactose-3-O-sulfotransferase 1
chr16_+_777246 0.18 ENST00000561546.1
ENST00000564545.1
ENST00000389703.3
ENST00000567414.1
ENST00000568141.1
hydroxyacylglutathione hydrolase-like
chr8_+_99956759 0.17 ENST00000522510.1
ENST00000457907.2
odd-skipped related transciption factor 2
chr3_-_49823941 0.17 ENST00000321599.4
ENST00000395238.1
ENST00000468463.1
ENST00000460540.1
inositol hexakisphosphate kinase 1
chr11_+_86502085 0.17 ENST00000527521.1
protease, serine, 23
chr12_+_133067157 0.17 ENST00000261673.6
fibrosin-like 1
chr1_+_202995611 0.17 ENST00000367240.2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
chr19_-_55574538 0.17 ENST00000415061.3
retinol dehydrogenase 13 (all-trans/9-cis)
chr22_-_39239987 0.16 ENST00000333039.2
neuronal pentraxin receptor
chr22_+_46546494 0.16 ENST00000396000.2
ENST00000262735.5
ENST00000420804.1
peroxisome proliferator-activated receptor alpha
chr8_+_124429006 0.16 ENST00000522194.1
ENST00000523356.1
WDYHV motif containing 1
chr16_-_67190152 0.16 ENST00000486556.1
TNFRSF1A-associated via death domain
chr3_-_179322436 0.16 ENST00000392659.2
ENST00000476781.1
mitochondrial ribosomal protein L47
chr3_-_49726104 0.15 ENST00000383728.3
ENST00000545762.1
macrophage stimulating 1 (hepatocyte growth factor-like)
chr11_-_3859089 0.15 ENST00000396979.1
ras homolog family member G
chr1_+_1260147 0.15 ENST00000343938.4
glycolipid transfer protein domain containing 1
chr12_+_120875910 0.15 ENST00000551806.1
Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial
chr12_-_100656134 0.15 ENST00000548313.1
DEP domain containing 4
chr11_-_68611721 0.15 ENST00000561996.1
carnitine palmitoyltransferase 1A (liver)
chr19_-_7293942 0.15 ENST00000341500.5
ENST00000302850.5
insulin receptor
chr11_+_67798090 0.15 ENST00000313468.5
NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
chr11_+_77899920 0.15 ENST00000528910.1
ENST00000529308.1
ubiquitin specific peptidase 35
chr15_-_94614049 0.15 ENST00000556447.1
ENST00000555772.1
CTD-3049M7.1
chr8_+_67405794 0.15 ENST00000522977.1
ENST00000480005.1
chromosome 8 open reading frame 46
chr13_+_28519343 0.15 ENST00000381026.3
ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit pseudogene 2
chr17_+_39868577 0.15 ENST00000329402.3
gastrin
chr17_-_73505961 0.15 ENST00000433559.2
CASK interacting protein 2
chr11_-_3862206 0.15 ENST00000351018.4
ras homolog family member G
chr12_+_51632638 0.14 ENST00000549732.2
DAZ associated protein 2
chr6_-_43197189 0.14 ENST00000509253.1
ENST00000393987.2
ENST00000230431.6
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
chr22_+_40573921 0.14 ENST00000454349.2
ENST00000335727.9
trinucleotide repeat containing 6B
chr11_-_3862059 0.14 ENST00000396978.1
ras homolog family member G
chr19_-_15236470 0.14 ENST00000533747.1
ENST00000598709.1
ENST00000534378.1
ilvB (bacterial acetolactate synthase)-like
chr8_+_99956662 0.14 ENST00000523368.1
ENST00000297565.4
ENST00000435298.2
odd-skipped related transciption factor 2
chr2_+_217498105 0.14 ENST00000233809.4
insulin-like growth factor binding protein 2, 36kDa
chr19_+_45251804 0.14 ENST00000164227.5
B-cell CLL/lymphoma 3
chr1_-_211752073 0.14 ENST00000367001.4
solute carrier family 30 (zinc transporter), member 1
chr16_-_67694597 0.14 ENST00000393919.4
ENST00000219251.8
adrenocortical dysplasia homolog (mouse)
chr17_+_900342 0.13 ENST00000327158.4
translocase of inner mitochondrial membrane 22 homolog (yeast)
chr19_+_3185910 0.13 ENST00000588428.1
nicalin
chr17_-_79792909 0.13 ENST00000330261.4
ENST00000570394.1
protein phosphatase 1, regulatory subunit 27
chr16_+_4674787 0.13 ENST00000262370.7
mahogunin ring finger 1, E3 ubiquitin protein ligase
chr9_+_133978190 0.13 ENST00000372312.3
allograft inflammatory factor 1-like
chr7_+_2443202 0.13 ENST00000258711.6
carbohydrate (chondroitin 4) sulfotransferase 12
chr4_+_119512928 0.13 ENST00000567913.2
RP11-384K6.6
chr3_-_156840776 0.13 ENST00000471357.1
long intergenic non-protein coding RNA 880
chr16_-_89787360 0.13 ENST00000389386.3
VPS9 domain containing 1
chr4_-_1723040 0.13 ENST00000382936.3
ENST00000536901.1
ENST00000303277.2
transmembrane protein 129
chr14_-_102976091 0.13 ENST00000286918.4
ankyrin repeat domain 9
chr6_-_33547975 0.13 ENST00000442998.2
ENST00000360661.5
BCL2-antagonist/killer 1
chr17_+_38975358 0.13 ENST00000436612.1
ENST00000301665.3
transmembrane protein 99
chr17_+_79670386 0.13 ENST00000333676.3
ENST00000571730.1
ENST00000541223.1
mitochondrial ribosomal protein L12
Mitochondrial dicarboxylate carrier; Uncharacterized protein; cDNA FLJ60124, highly similar to Mitochondrial dicarboxylate carrier
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
chr6_-_97345689 0.13 ENST00000316149.7
NADH dehydrogenase (ubiquinone) complex I, assembly factor 4
chr11_+_62623544 0.13 ENST00000377890.2
ENST00000377891.2
ENST00000377889.2
solute carrier family 3 (amino acid transporter heavy chain), member 2
chr3_-_10028366 0.12 ENST00000429759.1
ER membrane protein complex subunit 3
chr11_+_62623621 0.12 ENST00000535296.1
solute carrier family 3 (amino acid transporter heavy chain), member 2
chr19_+_1248547 0.12 ENST00000586757.1
ENST00000300952.2
midnolin
chr18_-_56985873 0.12 ENST00000299721.3
complexin 4
chr18_-_43678241 0.12 ENST00000593152.2
ENST00000589252.1
ENST00000590665.1
ENST00000398752.6
ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
chr12_-_53320245 0.12 ENST00000552150.1
keratin 8
chr5_-_140027175 0.12 ENST00000512088.1
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
chr11_+_65769946 0.12 ENST00000533166.1
barrier to autointegration factor 1
chr16_+_31366455 0.12 ENST00000268296.4
integrin, alpha X (complement component 3 receptor 4 subunit)
chr6_+_30749649 0.12 ENST00000422944.1
HLA complex group 20 (non-protein coding)
chr12_+_6976687 0.12 ENST00000396705.5
triosephosphate isomerase 1
chr12_+_121163602 0.12 ENST00000411593.2
acyl-CoA dehydrogenase, C-2 to C-3 short chain
chr11_+_62623512 0.12 ENST00000377892.1
solute carrier family 3 (amino acid transporter heavy chain), member 2
chr11_+_6411636 0.12 ENST00000299397.3
ENST00000356761.2
ENST00000342245.4
sphingomyelin phosphodiesterase 1, acid lysosomal
chr8_+_11188397 0.12 ENST00000382435.4
solute carrier family 35, member G5
chr19_-_3062881 0.12 ENST00000586742.1
amino-terminal enhancer of split
chr16_-_69390209 0.12 ENST00000563634.1
Uncharacterized protein
chr15_-_77988485 0.11 ENST00000561030.1
leucine rich repeat and Ig domain containing 1
chr22_+_30821784 0.11 ENST00000407550.3
mitochondrial fission process 1
chr17_+_74723031 0.11 ENST00000586200.1
methyltransferase like 23
chr9_-_140095186 0.11 ENST00000409012.4
taperin
chr16_-_57481278 0.11 ENST00000567751.1
ENST00000568940.1
ENST00000563341.1
ENST00000565961.1
ENST00000569370.1
ENST00000567518.1
ENST00000565786.1
ENST00000394391.4
cytokine induced apoptosis inhibitor 1
chr17_+_74075263 0.11 ENST00000334586.5
ENST00000392503.2
zinc activated ligand-gated ion channel
chr2_+_219135115 0.11 ENST00000248451.3
ENST00000273077.4
paroxysmal nonkinesigenic dyskinesia
chr19_-_3063099 0.11 ENST00000221561.8
amino-terminal enhancer of split
chr1_+_33231268 0.11 ENST00000373480.1
KIAA1522
chr16_-_19896832 0.11 ENST00000537135.1
ENST00000564449.1
G protein-coupled receptor, family C, group 5, member B
chr11_+_63742050 0.11 ENST00000314133.3
ENST00000535431.1
cytochrome c oxidase subunit VIIIA (ubiquitous)
Uncharacterized protein
chr8_+_66933779 0.11 ENST00000276570.5
DnaJ (Hsp40) homolog, subfamily C, member 5 beta
chr15_+_43809797 0.11 ENST00000399453.1
ENST00000300231.5
microtubule-associated protein 1A
chr19_+_18726786 0.11 ENST00000594709.1
transmembrane protein 59-like
chr7_+_76107444 0.11 ENST00000435861.1
deltex homolog 2 (Drosophila)
chr19_+_46171464 0.11 ENST00000590918.1
ENST00000263281.3
ENST00000304207.8
gastric inhibitory polypeptide receptor
chr11_+_122733011 0.11 ENST00000533709.1
cytotoxic and regulatory T cell molecule
chr4_-_21699380 0.11 ENST00000382148.3
Kv channel interacting protein 4
chr19_+_29704142 0.11 ENST00000587859.1
ENST00000590607.1
CTB-32O4.2
chr3_-_49158218 0.11 ENST00000417901.1
ENST00000306026.5
ENST00000434032.2
ubiquitin specific peptidase 19
chr7_-_105029812 0.11 ENST00000482897.1
SRSF protein kinase 2
chr1_-_153514241 0.11 ENST00000368718.1
ENST00000359215.1
S100 calcium binding protein A5
chr22_+_30792980 0.11 ENST00000403484.1
ENST00000405717.3
ENST00000402592.3
SEC14-like 2 (S. cerevisiae)
chr1_-_20834586 0.10 ENST00000264198.3
mitochondrial E3 ubiquitin protein ligase 1
chr3_-_52312337 0.10 ENST00000469000.1
WD repeat domain 82
chr3_-_52443799 0.10 ENST00000470173.1
ENST00000296288.5
BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
chr13_-_111214015 0.10 ENST00000267328.3
RAB20, member RAS oncogene family
chr8_+_101349823 0.10 ENST00000519566.1
KB-1991G8.1
chr19_-_49016418 0.10 ENST00000270238.3
lemur tyrosine kinase 3
chr20_+_3776371 0.10 ENST00000245960.5
cell division cycle 25B
chr11_-_64511575 0.10 ENST00000431822.1
ENST00000377486.3
ENST00000394432.3
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr21_-_46330545 0.10 ENST00000320216.6
ENST00000397852.1
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr2_-_96926313 0.10 ENST00000435268.1
transmembrane protein 127
chr11_-_6462210 0.10 ENST00000265983.3
hemopexin
chr9_+_131873227 0.10 ENST00000358994.4
ENST00000455292.1
protein phosphatase 2A activator, regulatory subunit 4
chr22_+_42372764 0.10 ENST00000396426.3
ENST00000406029.1
septin 3
chr16_-_70729496 0.10 ENST00000567648.1
Vac14 homolog (S. cerevisiae)
chr19_-_40931891 0.10 ENST00000357949.4
SERTA domain containing 1
chr6_-_13328050 0.10 ENST00000420456.1
TBC1 domain family, member 7
chr9_-_131872928 0.10 ENST00000455830.2
ENST00000393384.3
ENST00000318080.2
carnitine O-acetyltransferase
chr20_+_1875942 0.10 ENST00000358771.4
signal-regulatory protein alpha
chr17_-_2169425 0.10 ENST00000570606.1
ENST00000354901.4
SMG6 nonsense mediated mRNA decay factor
chr14_-_24911868 0.10 ENST00000554698.1
short chain dehydrogenase/reductase family 39U, member 1
chr9_-_130889990 0.10 ENST00000449878.1
prostaglandin E synthase 2
chr22_+_30792846 0.10 ENST00000312932.9
ENST00000428195.1
SEC14-like 2 (S. cerevisiae)
chr1_-_157108266 0.10 ENST00000326786.4
ets variant 3
chr22_+_30163340 0.10 ENST00000330029.6
ENST00000401406.3
ubiquinol-cytochrome c reductase, complex III subunit X
chr16_+_680932 0.09 ENST00000319070.2
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1

Network of associatons between targets according to the STRING database.

First level regulatory network of ESRRB_ESRRG

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0015729 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356)
0.2 0.5 GO:0072361 regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter(GO:0072361)
0.1 0.3 GO:0048597 B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597)
0.1 0.7 GO:0021590 cerebellum maturation(GO:0021590) cerebellar cortex maturation(GO:0021699)
0.1 0.5 GO:0052330 induction of programmed cell death(GO:0012502) positive regulation of apoptotic process in other organism(GO:0044533) positive regulation by symbiont of host programmed cell death(GO:0052042) positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052330) positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction(GO:0052501)
0.1 0.6 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.1 0.2 GO:0070676 intralumenal vesicle formation(GO:0070676)
0.1 0.2 GO:0006218 uridine catabolic process(GO:0006218)
0.1 0.2 GO:0007506 gonadal mesoderm development(GO:0007506)
0.1 1.2 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.1 0.2 GO:1900075 regulation of neuromuscular synaptic transmission(GO:1900073) positive regulation of neuromuscular synaptic transmission(GO:1900075)
0.1 0.4 GO:0060356 leucine import(GO:0060356)
0.0 0.2 GO:0002415 immune response in mucosal-associated lymphoid tissue(GO:0002386) immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.0 0.1 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.0 0.1 GO:0060381 regulation of single-stranded telomeric DNA binding(GO:0060380) positive regulation of single-stranded telomeric DNA binding(GO:0060381)
0.0 0.3 GO:0036022 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.0 0.1 GO:0006533 aspartate catabolic process(GO:0006533)
0.0 0.1 GO:1990535 neuron projection maintenance(GO:1990535)
0.0 0.1 GO:0061727 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.7 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.2 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.0 0.1 GO:1901526 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.0 0.1 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.0 0.1 GO:0018194 N-terminal protein amino acid methylation(GO:0006480) N-terminal peptidyl-alanine methylation(GO:0018011) N-terminal peptidyl-alanine trimethylation(GO:0018012) N-terminal peptidyl-glycine methylation(GO:0018013) N-terminal peptidyl-proline dimethylation(GO:0018016) peptidyl-alanine modification(GO:0018194) N-terminal peptidyl-proline methylation(GO:0035568) N-terminal peptidyl-serine methylation(GO:0035570) N-terminal peptidyl-serine dimethylation(GO:0035572) N-terminal peptidyl-serine trimethylation(GO:0035573)
0.0 0.4 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.5 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.3 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.0 0.1 GO:0046166 glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.0 0.3 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.1 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.1 GO:0019242 methylglyoxal biosynthetic process(GO:0019242)
0.0 0.1 GO:0045362 interleukin-1 biosynthetic process(GO:0042222) regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.0 0.1 GO:1902869 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) regulation of amacrine cell differentiation(GO:1902869) positive regulation of amacrine cell differentiation(GO:1902871)
0.0 0.2 GO:0023021 termination of signal transduction(GO:0023021)
0.0 0.1 GO:0002368 B cell cytokine production(GO:0002368)
0.0 0.1 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.1 GO:0009822 alkaloid catabolic process(GO:0009822)
0.0 0.1 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.1 GO:0061145 bronchus cartilage development(GO:0060532) lung smooth muscle development(GO:0061145)
0.0 0.2 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.1 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.2 GO:0030450 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.0 0.2 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.2 GO:0070305 response to cGMP(GO:0070305) cellular response to cGMP(GO:0071321)
0.0 0.1 GO:1903721 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
0.0 0.1 GO:1902824 cleavage furrow ingression(GO:0036090) positive regulation of late endosome to lysosome transport(GO:1902824)
0.0 0.1 GO:0015680 intracellular copper ion transport(GO:0015680)
0.0 0.1 GO:0061687 detoxification of inorganic compound(GO:0061687)
0.0 0.2 GO:0009644 response to high light intensity(GO:0009644)
0.0 0.2 GO:0070508 sterol import(GO:0035376) cholesterol import(GO:0070508)
0.0 0.1 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.0 0.1 GO:0048808 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0 0.0 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.0 0.1 GO:1900063 regulation of peroxisome organization(GO:1900063)
0.0 0.1 GO:0071543 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 1.1 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.1 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.0 0.1 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.2 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.4 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.0 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159) renal albumin absorption(GO:0097018) regulation of renal albumin absorption(GO:2000532)
0.0 0.1 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.2 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.1 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.0 0.2 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.0 0.2 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.0 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.0 0.3 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.3 GO:0014850 response to muscle activity(GO:0014850)
0.0 0.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.0 GO:0045763 negative regulation of cellular amino acid metabolic process(GO:0045763)
0.0 0.2 GO:0007144 female meiosis I(GO:0007144)
0.0 0.2 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
0.0 0.4 GO:1900027 regulation of ruffle assembly(GO:1900027)
0.0 0.1 GO:0090383 phagosome acidification(GO:0090383)
0.0 0.1 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 0.0 GO:0052255 induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0097452 GAIT complex(GO:0097452)
0.1 0.4 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.1 GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 0.5 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.1 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.0 0.4 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.3 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.1 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 0.2 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.2 GO:0099634 postsynaptic specialization membrane(GO:0099634)
0.0 0.1 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.1 GO:0032021 NELF complex(GO:0032021)
0.0 1.0 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.1 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.1 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.0 0.1 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.0 GO:0055087 Ski complex(GO:0055087)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.2 1.2 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.2 0.6 GO:0015117 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131)
0.1 0.5 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) aspartic-type endopeptidase inhibitor activity(GO:0019828) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1 0.3 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
0.1 0.2 GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.1 0.2 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.1 0.2 GO:0052839 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.1 0.4 GO:0043532 angiostatin binding(GO:0043532)
0.1 0.4 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.1 0.2 GO:0008431 vitamin E binding(GO:0008431)
0.1 0.2 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.0 0.2 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.0 0.1 GO:0030943 mitochondrion targeting sequence binding(GO:0030943)
0.0 0.1 GO:0070546 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0 0.5 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.1 GO:0004807 triose-phosphate isomerase activity(GO:0004807)
0.0 0.1 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.4 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.1 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.0 0.2 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.0 0.1 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.1 GO:0004144 2-acylglycerol O-acyltransferase activity(GO:0003846) diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 0.1 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.1 GO:0004347 glucose-6-phosphate isomerase activity(GO:0004347)
0.0 0.6 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.2 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.3 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.6 GO:0031005 filamin binding(GO:0031005)
0.0 0.2 GO:0070513 death domain binding(GO:0070513)
0.0 0.3 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.2 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.1 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.0 0.2 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.1 GO:0030343 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0 0.8 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.1 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.2 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.4 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.1 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 1.1 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.3 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.0 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.0 0.2 GO:0032052 bile acid binding(GO:0032052)
0.0 0.1 GO:0052847 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.0 0.1 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.3 GO:0051400 BH domain binding(GO:0051400)
0.0 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.3 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0008169 C-methyltransferase activity(GO:0008169) rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383)
0.0 0.1 GO:0034511 U3 snoRNA binding(GO:0034511)
0.0 0.0 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.0 0.1 GO:0010736 serum response element binding(GO:0010736)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.2 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.1 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.1 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.0 0.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.3 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.3 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME SHC RELATED EVENTS Genes involved in SHC-related events
0.0 1.5 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.4 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.3 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.7 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.3 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.1 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.3 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.6 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression