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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for EZH2

Z-value: 1.43

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Transcription factors associated with EZH2

Gene Symbol Gene ID Gene Info
EZH2
ENSG00000106462.6 enhancer of zeste 2 polycomb repressive complex 2 subunit

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
EZH2hg19_v2_chr7_-_148581251_148581347-0.821.8e-01Click!

Activity profile of EZH2 motif

Sorted Z-values of EZH2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_51152702 2.05 ENST00000425202.1
C19orf81
chromosome 19 open reading frame 81
chr5_+_175298487 2.04 ENST00000393745.3
CPLX2
complexin 2
chr5_+_175298573 1.82 ENST00000512824.1
CPLX2
complexin 2
chr5_+_175298674 1.57 ENST00000514150.1
CPLX2
complexin 2
chr19_-_56056888 0.81 ENST00000592464.1
ENST00000420723.3
SBK3
SH3 domain binding kinase family, member 3
chr15_+_91416092 0.77 ENST00000559353.1
FURIN
furin (paired basic amino acid cleaving enzyme)
chr10_-_75168071 0.77 ENST00000394847.3
ANXA7
annexin A7
chr9_+_131902283 0.75 ENST00000436883.1
ENST00000414510.1
PPP2R4
protein phosphatase 2A activator, regulatory subunit 4
chr11_-_44331679 0.74 ENST00000329255.3
ALX4
ALX homeobox 4
chrY_+_15418467 0.73 ENST00000595988.1
AC010877.1
Uncharacterized protein
chr16_+_30709530 0.71 ENST00000411466.2
SRCAP
Snf2-related CREBBP activator protein
chr17_+_7123207 0.69 ENST00000584103.1
ENST00000579886.2
ACADVL
acyl-CoA dehydrogenase, very long chain
chr5_+_149865377 0.68 ENST00000522491.1
NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr5_+_92919043 0.58 ENST00000327111.3
NR2F1
nuclear receptor subfamily 2, group F, member 1
chr11_-_66056596 0.55 ENST00000471387.2
ENST00000359461.6
ENST00000376901.4
YIF1A
Yip1 interacting factor homolog A (S. cerevisiae)
chr10_-_81932771 0.52 ENST00000437799.1
ANXA11
annexin A11
chr9_-_14322319 0.52 ENST00000606230.1
NFIB
nuclear factor I/B
chr17_+_75316336 0.48 ENST00000591934.1
SEPT9
septin 9
chr8_+_22428457 0.45 ENST00000517962.1
SORBS3
sorbin and SH3 domain containing 3
chr12_+_7022909 0.44 ENST00000537688.1
ENO2
enolase 2 (gamma, neuronal)
chr2_+_121493717 0.44 ENST00000418323.1
GLI2
GLI family zinc finger 2
chr5_+_102200948 0.44 ENST00000511477.1
ENST00000506006.1
ENST00000509832.1
PAM
peptidylglycine alpha-amidating monooxygenase
chr17_+_55183261 0.43 ENST00000576295.1
AKAP1
A kinase (PRKA) anchor protein 1
chr9_+_131902346 0.42 ENST00000432124.1
ENST00000435305.1
PPP2R4
protein phosphatase 2A activator, regulatory subunit 4
chr5_+_158527630 0.42 ENST00000523301.1
RP11-175K6.1
RP11-175K6.1
chr19_+_1261106 0.42 ENST00000588411.1
CIRBP
cold inducible RNA binding protein
chr14_-_23284703 0.41 ENST00000555911.1
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr14_+_77244349 0.40 ENST00000554743.1
VASH1
vasohibin 1
chrX_+_152990302 0.40 ENST00000218104.3
ABCD1
ATP-binding cassette, sub-family D (ALD), member 1
chr16_+_30662085 0.40 ENST00000569864.1
PRR14
proline rich 14
chr7_+_13141010 0.39 ENST00000443947.1
AC011288.2
AC011288.2
chr3_-_157824292 0.38 ENST00000483851.2
SHOX2
short stature homeobox 2
chr16_-_1020954 0.38 ENST00000543238.1
ENST00000539379.1
ENST00000399843.2
ENST00000262301.11
LMF1
lipase maturation factor 1
chr11_+_57559005 0.37 ENST00000534647.1
CTNND1
catenin (cadherin-associated protein), delta 1
chr2_+_210288760 0.37 ENST00000199940.6
MAP2
microtubule-associated protein 2
chr3_-_120400960 0.36 ENST00000476082.2
HGD
homogentisate 1,2-dioxygenase
chr6_-_31697255 0.36 ENST00000436437.1
DDAH2
dimethylarginine dimethylaminohydrolase 2
chr3_-_129035120 0.36 ENST00000333762.4
H1FX
H1 histone family, member X
chr2_+_220462560 0.36 ENST00000456909.1
ENST00000295641.10
STK11IP
serine/threonine kinase 11 interacting protein
chr14_-_23285069 0.36 ENST00000554758.1
ENST00000397528.4
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr6_-_113754604 0.35 ENST00000421737.1
RP1-124C6.1
RP1-124C6.1
chr4_-_159094194 0.35 ENST00000592057.1
ENST00000585682.1
ENST00000393807.5
FAM198B
family with sequence similarity 198, member B
chr13_-_45048386 0.35 ENST00000472477.1
TSC22D1
TSC22 domain family, member 1
chr6_+_30848771 0.35 ENST00000503180.1
DDR1
discoidin domain receptor tyrosine kinase 1
chr17_-_7387524 0.35 ENST00000311403.4
ZBTB4
zinc finger and BTB domain containing 4
chr2_-_220436248 0.35 ENST00000265318.4
OBSL1
obscurin-like 1
chr16_+_29911864 0.35 ENST00000308748.5
ASPHD1
aspartate beta-hydroxylase domain containing 1
chr5_+_175223313 0.34 ENST00000359546.4
CPLX2
complexin 2
chr22_-_39268192 0.34 ENST00000216083.6
CBX6
chromobox homolog 6
chrX_+_100878112 0.33 ENST00000491568.2
ENST00000479298.1
ARMCX3
armadillo repeat containing, X-linked 3
chr17_-_46806540 0.33 ENST00000290295.7
HOXB13
homeobox B13
chr17_-_47045949 0.33 ENST00000357424.2
GIP
gastric inhibitory polypeptide
chr16_-_89785777 0.33 ENST00000561976.1
VPS9D1
VPS9 domain containing 1
chr16_-_19725899 0.33 ENST00000567367.1
KNOP1
lysine-rich nucleolar protein 1
chr5_-_158526756 0.32 ENST00000313708.6
ENST00000517373.1
EBF1
early B-cell factor 1
chr19_-_46405861 0.32 ENST00000322217.5
MYPOP
Myb-related transcription factor, partner of profilin
chr7_-_100881109 0.32 ENST00000308344.5
CLDN15
claudin 15
chr13_-_108518986 0.32 ENST00000375915.2
FAM155A
family with sequence similarity 155, member A
chr6_+_30848829 0.32 ENST00000508317.1
DDR1
discoidin domain receptor tyrosine kinase 1
chr17_-_46724186 0.32 ENST00000433510.2
RP11-357H14.17
RP11-357H14.17
chr10_-_77161533 0.31 ENST00000535216.1
ZNF503
zinc finger protein 503
chr6_+_35744367 0.31 ENST00000360454.2
ENST00000403376.3
CLPSL2
colipase-like 2
chr19_-_36505098 0.31 ENST00000252984.7
ENST00000486389.1
ENST00000378875.3
ENST00000485128.1
ALKBH6
alkB, alkylation repair homolog 6 (E. coli)
chr5_-_141703713 0.30 ENST00000511815.1
SPRY4
sprouty homolog 4 (Drosophila)
chr17_+_75276643 0.30 ENST00000589070.1
SEPT9
septin 9
chr3_-_187455680 0.30 ENST00000438077.1
BCL6
B-cell CLL/lymphoma 6
chr12_-_6483969 0.30 ENST00000396966.2
SCNN1A
sodium channel, non-voltage-gated 1 alpha subunit
chr2_+_66662249 0.29 ENST00000560281.2
MEIS1
Meis homeobox 1
chr1_+_155023757 0.29 ENST00000356955.2
ENST00000449910.2
ENST00000359280.4
ENST00000360674.4
ENST00000368412.3
ENST00000355956.2
ENST00000368410.2
ENST00000271836.6
ENST00000368413.1
ENST00000531455.1
ENST00000447332.3
ADAM15
ADAM metallopeptidase domain 15
chr17_-_45918539 0.29 ENST00000584123.1
ENST00000578323.1
ENST00000407215.3
ENST00000290216.9
SCRN2
secernin 2
chr9_+_127539425 0.29 ENST00000331715.9
OLFML2A
olfactomedin-like 2A
chr1_+_225600404 0.28 ENST00000366845.2
AC092811.1
AC092811.1
chr2_-_118943930 0.28 ENST00000449075.1
ENST00000414886.1
ENST00000449819.1
AC093901.1
AC093901.1
chr12_+_6930703 0.28 ENST00000311268.3
GPR162
G protein-coupled receptor 162
chr2_-_190044480 0.28 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr15_-_88799948 0.28 ENST00000394480.2
NTRK3
neurotrophic tyrosine kinase, receptor, type 3
chr3_-_112360116 0.27 ENST00000206423.3
ENST00000439685.2
CCDC80
coiled-coil domain containing 80
chr18_+_72166564 0.27 ENST00000583216.1
ENST00000581912.1
ENST00000582589.1
CNDP2
CNDP dipeptidase 2 (metallopeptidase M20 family)
chr19_+_41903709 0.27 ENST00000542943.1
ENST00000457836.2
BCKDHA
branched chain keto acid dehydrogenase E1, alpha polypeptide
chr22_-_39268308 0.27 ENST00000407418.3
CBX6
chromobox homolog 6
chr2_+_28615669 0.27 ENST00000379619.1
ENST00000264716.4
FOSL2
FOS-like antigen 2
chr12_-_6715808 0.27 ENST00000545584.1
CHD4
chromodomain helicase DNA binding protein 4
chr17_-_8027402 0.27 ENST00000541682.2
ENST00000317814.4
ENST00000577735.1
HES7
hes family bHLH transcription factor 7
chr12_+_6930813 0.27 ENST00000428545.2
GPR162
G protein-coupled receptor 162
chr15_+_81293254 0.27 ENST00000267984.2
MESDC1
mesoderm development candidate 1
chr16_+_31085714 0.27 ENST00000300850.5
ENST00000564189.1
ENST00000428260.1
ZNF646
zinc finger protein 646
chr1_+_157963063 0.27 ENST00000360089.4
ENST00000368173.3
ENST00000392272.2
KIRREL
kin of IRRE like (Drosophila)
chr2_+_217363559 0.27 ENST00000600880.1
ENST00000446558.1
RPL37A
ribosomal protein L37a
chr19_-_12992244 0.27 ENST00000538460.1
DNASE2
deoxyribonuclease II, lysosomal
chr17_+_21729899 0.26 ENST00000583708.1
UBBP4
ubiquitin B pseudogene 4
chr4_-_153457197 0.26 ENST00000281708.4
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr16_-_29934558 0.26 ENST00000568995.1
ENST00000566413.1
KCTD13
potassium channel tetramerization domain containing 13
chr7_+_140396465 0.26 ENST00000476279.1
ENST00000247866.4
ENST00000461457.1
ENST00000465506.1
ENST00000204307.5
ENST00000464566.1
NDUFB2
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa
chr1_+_20878932 0.26 ENST00000332947.4
FAM43B
family with sequence similarity 43, member B
chr17_+_4846101 0.26 ENST00000576965.1
RNF167
ring finger protein 167
chr6_-_43484621 0.25 ENST00000506469.1
ENST00000503972.1
YIPF3
Yip1 domain family, member 3
chr6_-_168397757 0.25 ENST00000456585.1
ENST00000414364.1
KIF25-AS1
KIF25 antisense RNA 1
chrX_+_70316005 0.25 ENST00000374259.3
FOXO4
forkhead box O4
chr6_+_32132360 0.25 ENST00000333845.6
ENST00000395512.1
ENST00000432129.1
EGFL8
EGF-like-domain, multiple 8
chr17_+_42148225 0.25 ENST00000591696.1
G6PC3
glucose 6 phosphatase, catalytic, 3
chr8_+_22857048 0.25 ENST00000251822.6
RHOBTB2
Rho-related BTB domain containing 2
chr1_-_150208320 0.25 ENST00000534220.1
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr19_-_40440533 0.25 ENST00000221347.6
FCGBP
Fc fragment of IgG binding protein
chr16_+_31483451 0.25 ENST00000565360.1
ENST00000361773.3
TGFB1I1
transforming growth factor beta 1 induced transcript 1
chr12_-_56652111 0.25 ENST00000267116.7
ANKRD52
ankyrin repeat domain 52
chr12_-_116714564 0.24 ENST00000548743.1
MED13L
mediator complex subunit 13-like
chr7_-_100076873 0.24 ENST00000300181.2
TSC22D4
TSC22 domain family, member 4
chr3_-_15563229 0.24 ENST00000383786.5
ENST00000383787.2
ENST00000383785.2
ENST00000383788.5
ENST00000603808.1
COLQ
collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
chr22_-_29663954 0.24 ENST00000216085.7
RHBDD3
rhomboid domain containing 3
chr8_+_22423168 0.24 ENST00000518912.1
ENST00000428103.1
SORBS3
sorbin and SH3 domain containing 3
chr5_+_137673200 0.24 ENST00000434981.2
FAM53C
family with sequence similarity 53, member C
chr6_-_37665751 0.24 ENST00000297153.7
ENST00000434837.3
MDGA1
MAM domain containing glycosylphosphatidylinositol anchor 1
chr11_-_117698765 0.24 ENST00000532119.1
FXYD2
FXYD domain containing ion transport regulator 2
chr10_-_77161650 0.24 ENST00000372524.4
ZNF503
zinc finger protein 503
chr4_-_80994471 0.24 ENST00000295465.4
ANTXR2
anthrax toxin receptor 2
chr5_+_59783941 0.24 ENST00000506884.1
ENST00000504876.2
PART1
prostate androgen-regulated transcript 1 (non-protein coding)
chr3_-_197300194 0.24 ENST00000358186.2
ENST00000431056.1
BDH1
3-hydroxybutyrate dehydrogenase, type 1
chr17_-_40575535 0.24 ENST00000357037.5
PTRF
polymerase I and transcript release factor
chr16_-_29875057 0.24 ENST00000219789.6
CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase
chr12_+_113376249 0.24 ENST00000551007.1
ENST00000548514.1
OAS3
2'-5'-oligoadenylate synthetase 3, 100kDa
chr9_-_34372830 0.24 ENST00000379142.3
KIAA1161
KIAA1161
chr14_-_23285011 0.23 ENST00000397532.3
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr12_+_6930964 0.23 ENST00000382315.3
GPR162
G protein-coupled receptor 162
chr17_+_7358889 0.23 ENST00000575379.1
CHRNB1
cholinergic receptor, nicotinic, beta 1 (muscle)
chr12_+_66218212 0.22 ENST00000393578.3
ENST00000425208.2
ENST00000536545.1
ENST00000354636.3
HMGA2
high mobility group AT-hook 2
chr16_+_69373471 0.22 ENST00000569637.2
NIP7
NIP7, nucleolar pre-rRNA processing protein
chr6_-_32143828 0.22 ENST00000412465.2
ENST00000375107.3
AGPAT1
1-acylglycerol-3-phosphate O-acyltransferase 1
chr2_-_216003127 0.22 ENST00000412081.1
ENST00000272895.7
ABCA12
ATP-binding cassette, sub-family A (ABC1), member 12
chr15_+_64428529 0.22 ENST00000560861.1
SNX1
sorting nexin 1
chr1_+_45274154 0.22 ENST00000450269.1
ENST00000453418.1
ENST00000409335.2
BTBD19
BTB (POZ) domain containing 19
chr22_+_24990746 0.22 ENST00000456869.1
ENST00000411974.1
GGT1
gamma-glutamyltransferase 1
chr19_-_54692132 0.22 ENST00000449249.1
MBOAT7
membrane bound O-acyltransferase domain containing 7
chr18_+_3450161 0.22 ENST00000551402.1
ENST00000577543.1
TGIF1
TGFB-induced factor homeobox 1
chr3_+_164924716 0.22 ENST00000470138.1
ENST00000498616.1
RP11-85M11.2
RP11-85M11.2
chr11_+_64008525 0.22 ENST00000449942.2
FKBP2
FK506 binding protein 2, 13kDa
chr10_-_75682535 0.22 ENST00000409178.1
C10orf55
chromosome 10 open reading frame 55
chr17_+_27895045 0.22 ENST00000580183.2
ENST00000578749.1
ENST00000582829.2
TP53I13
tumor protein p53 inducible protein 13
chr2_-_27435634 0.22 ENST00000430186.1
SLC5A6
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
chr1_-_153521714 0.22 ENST00000368713.3
S100A3
S100 calcium binding protein A3
chr9_+_130469257 0.22 ENST00000373295.2
C9orf117
chromosome 9 open reading frame 117
chr7_-_100076765 0.21 ENST00000393991.1
TSC22D4
TSC22 domain family, member 4
chr11_+_64008443 0.21 ENST00000309366.4
FKBP2
FK506 binding protein 2, 13kDa
chr6_+_32936942 0.21 ENST00000496118.2
BRD2
bromodomain containing 2
chr16_-_30773372 0.21 ENST00000545825.1
ENST00000541260.1
C16orf93
chromosome 16 open reading frame 93
chr12_-_118406777 0.21 ENST00000339824.5
KSR2
kinase suppressor of ras 2
chr16_+_31483374 0.21 ENST00000394863.3
TGFB1I1
transforming growth factor beta 1 induced transcript 1
chr17_-_71223839 0.21 ENST00000579872.1
ENST00000580032.1
FAM104A
family with sequence similarity 104, member A
chr20_-_62168714 0.21 ENST00000542869.1
PTK6
protein tyrosine kinase 6
chr1_-_155112883 0.20 ENST00000368399.1
ENST00000368400.4
ENST00000341298.3
DPM3
dolichyl-phosphate mannosyltransferase polypeptide 3
chr16_-_29910853 0.20 ENST00000308713.5
SEZ6L2
seizure related 6 homolog (mouse)-like 2
chr11_-_6255846 0.20 ENST00000449352.2
FAM160A2
family with sequence similarity 160, member A2
chr17_-_56494882 0.20 ENST00000584437.1
RNF43
ring finger protein 43
chr16_-_2260834 0.20 ENST00000562360.1
ENST00000566018.1
BRICD5
BRICHOS domain containing 5
chr9_+_35829208 0.20 ENST00000439587.2
ENST00000377991.4
TMEM8B
transmembrane protein 8B
chr15_+_59903975 0.20 ENST00000560585.1
ENST00000396065.1
GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr5_+_158527485 0.20 ENST00000517335.1
RP11-175K6.1
RP11-175K6.1
chr3_+_50654821 0.20 ENST00000457064.1
MAPKAPK3
mitogen-activated protein kinase-activated protein kinase 3
chr8_+_22438009 0.20 ENST00000409417.1
PDLIM2
PDZ and LIM domain 2 (mystique)
chr14_-_61124977 0.20 ENST00000554986.1
SIX1
SIX homeobox 1
chr1_-_153521597 0.20 ENST00000368712.1
S100A3
S100 calcium binding protein A3
chr17_+_67498396 0.20 ENST00000588110.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr1_+_145727681 0.20 ENST00000417171.1
ENST00000451928.2
PDZK1
PDZ domain containing 1
chr16_-_1020849 0.20 ENST00000568897.1
LMF1
lipase maturation factor 1
chr10_-_103454876 0.19 ENST00000331272.7
FBXW4
F-box and WD repeat domain containing 4
chr1_-_209824643 0.19 ENST00000391911.1
ENST00000415782.1
LAMB3
laminin, beta 3
chr17_-_46667594 0.19 ENST00000476342.1
ENST00000460160.1
ENST00000472863.1
HOXB3
homeobox B3
chr10_+_71389983 0.19 ENST00000373279.4
C10orf35
chromosome 10 open reading frame 35
chr15_+_90544532 0.19 ENST00000268154.4
ZNF710
zinc finger protein 710
chr19_+_51728316 0.19 ENST00000436584.2
ENST00000421133.2
ENST00000391796.3
ENST00000262262.4
CD33
CD33 molecule
chr9_-_34628104 0.19 ENST00000378909.2
ARID3C
AT rich interactive domain 3C (BRIGHT-like)
chr17_+_42148097 0.19 ENST00000269097.4
G6PC3
glucose 6 phosphatase, catalytic, 3
chr2_-_220435963 0.19 ENST00000373876.1
ENST00000404537.1
ENST00000603926.1
ENST00000373873.4
ENST00000289656.3
OBSL1
obscurin-like 1
chr1_+_18807424 0.19 ENST00000400664.1
KLHDC7A
kelch domain containing 7A
chr11_-_62414070 0.19 ENST00000540933.1
ENST00000346178.4
ENST00000356638.3
ENST00000534779.1
ENST00000525994.1
GANAB
glucosidase, alpha; neutral AB
chr16_+_30662050 0.19 ENST00000568754.1
PRR14
proline rich 14
chr11_-_17410869 0.19 ENST00000528731.1
KCNJ11
potassium inwardly-rectifying channel, subfamily J, member 11
chr17_-_56494908 0.19 ENST00000577716.1
RNF43
ring finger protein 43
chr15_-_59041954 0.19 ENST00000439637.1
ENST00000558004.1
ADAM10
ADAM metallopeptidase domain 10
chr1_-_154934200 0.19 ENST00000368457.2
PYGO2
pygopus family PHD finger 2
chr6_+_32146268 0.19 ENST00000427134.2
RNF5
ring finger protein 5, E3 ubiquitin protein ligase
chrX_+_99899180 0.19 ENST00000373004.3
SRPX2
sushi-repeat containing protein, X-linked 2
chr19_-_51289436 0.18 ENST00000562076.1
CTD-2568A17.1
CTD-2568A17.1
chr1_-_154943212 0.18 ENST00000368445.5
ENST00000448116.2
ENST00000368449.4
SHC1
SHC (Src homology 2 domain containing) transforming protein 1
chr10_+_1102303 0.18 ENST00000381329.1
WDR37
WD repeat domain 37
chr2_-_131099897 0.18 ENST00000409127.1
ENST00000437688.2
ENST00000259229.2
CCDC115
coiled-coil domain containing 115
chr15_-_65117807 0.18 ENST00000559239.1
ENST00000268043.4
ENST00000333425.6
PIF1
PIF1 5'-to-3' DNA helicase
chr20_-_62168672 0.18 ENST00000217185.2
PTK6
protein tyrosine kinase 6
chr7_-_100881041 0.18 ENST00000412417.1
ENST00000414035.1
CLDN15
claudin 15
chr4_+_102268904 0.18 ENST00000527564.1
ENST00000529296.1
AP001816.1
Uncharacterized protein
chr14_+_50234827 0.18 ENST00000554589.1
ENST00000557247.1
KLHDC2
kelch domain containing 2
chr17_+_7338737 0.18 ENST00000323206.1
ENST00000396568.1
TMEM102
transmembrane protein 102
chr1_+_117544366 0.18 ENST00000256652.4
ENST00000369470.1
CD101
CD101 molecule
chr16_-_29874211 0.18 ENST00000563415.1
CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase
chr9_+_140500087 0.18 ENST00000371421.4
ARRDC1
arrestin domain containing 1
chr14_+_23352374 0.18 ENST00000267396.4
ENST00000536884.1
REM2
RAS (RAD and GEM)-like GTP binding 2
chr6_-_79944336 0.18 ENST00000344726.5
ENST00000275036.7
HMGN3
high mobility group nucleosomal binding domain 3
chr15_+_43885799 0.17 ENST00000449946.1
ENST00000417289.1
CKMT1B
creatine kinase, mitochondrial 1B
chr8_+_22423219 0.17 ENST00000523965.1
ENST00000521554.1
SORBS3
sorbin and SH3 domain containing 3
chr6_-_43484718 0.17 ENST00000372422.2
YIPF3
Yip1 domain family, member 3
chr22_+_29664241 0.17 ENST00000436425.1
ENST00000447973.1
EWSR1
EWS RNA-binding protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of EZH2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0090472 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.2 5.4 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.1 0.4 GO:0021776 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.1 0.5 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 0.4 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.1 1.0 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.1 0.4 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.1 0.3 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.3 GO:2000729 positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.1 0.3 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1 0.3 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764) negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.1 0.4 GO:0072709 cellular response to sorbitol(GO:0072709)
0.1 0.3 GO:0052026 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.1 0.2 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.1 0.2 GO:0001172 transcription, RNA-templated(GO:0001172)
0.1 0.1 GO:0072194 kidney smooth muscle tissue development(GO:0072194)
0.1 0.6 GO:0021730 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740)
0.1 0.4 GO:0018032 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
0.1 0.3 GO:0021623 optic cup structural organization(GO:0003409) oculomotor nerve morphogenesis(GO:0021622) oculomotor nerve formation(GO:0021623)
0.1 0.2 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.2 GO:0035627 ceramide transport(GO:0035627)
0.1 0.3 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.1 0.1 GO:2000812 regulation of barbed-end actin filament capping(GO:2000812)
0.1 0.5 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1 0.4 GO:0070092 regulation of glucagon secretion(GO:0070092)
0.1 0.5 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.1 0.2 GO:0060796 regulation of transcription involved in primary germ layer cell fate commitment(GO:0060796)
0.1 0.2 GO:0070460 thyroid-stimulating hormone secretion(GO:0070460) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.1 0.7 GO:0006477 protein sulfation(GO:0006477)
0.1 0.2 GO:2000588 positive regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000588)
0.0 0.7 GO:0046322 negative regulation of fatty acid oxidation(GO:0046322)
0.0 0.1 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.1 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.0 0.3 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.0 0.3 GO:0001555 oocyte growth(GO:0001555)
0.0 0.1 GO:2001302 lipoxin biosynthetic process(GO:2001301) lipoxin A4 metabolic process(GO:2001302) lipoxin A4 biosynthetic process(GO:2001303)
0.0 0.3 GO:0072553 terminal button organization(GO:0072553)
0.0 0.2 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.0 0.4 GO:0070235 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.2 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.4 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.2 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
0.0 0.4 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.4 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.2 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.0 0.4 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.0 0.6 GO:0034382 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830)
0.0 0.1 GO:1903566 ciliary basal body organization(GO:0032053) positive regulation of protein localization to cilium(GO:1903566)
0.0 0.4 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.4 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.1 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.3 GO:1990785 response to water-immersion restraint stress(GO:1990785)
0.0 0.1 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.2 GO:0015887 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887)
0.0 0.1 GO:1904117 response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
0.0 0.9 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.3 GO:0006007 glucose catabolic process(GO:0006007) NADH metabolic process(GO:0006734) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.2 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.2 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.5 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.1 GO:0048852 diencephalon morphogenesis(GO:0048852)
0.0 0.1 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.1 GO:0052362 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.0 0.2 GO:0044858 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.0 0.1 GO:0036343 psychomotor behavior(GO:0036343)
0.0 0.2 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.7 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 0.1 GO:0060535 trachea cartilage morphogenesis(GO:0060535) inner medullary collecting duct development(GO:0072061)
0.0 0.1 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.1 GO:0097535 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.0 0.2 GO:0072275 metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.0 0.2 GO:0021553 olfactory nerve development(GO:0021553)
0.0 0.1 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.0 0.2 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.0 0.1 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
0.0 0.1 GO:0019249 lactate biosynthetic process(GO:0019249)
0.0 0.1 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.0 0.3 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.2 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.1 GO:0009624 response to nematode(GO:0009624) regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.0 0.1 GO:0002605 negative regulation of dendritic cell antigen processing and presentation(GO:0002605) regulation of cytotoxic T cell degranulation(GO:0043317) negative regulation of cytotoxic T cell degranulation(GO:0043318)
0.0 0.1 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.0 0.1 GO:0015793 glycerol transport(GO:0015793)
0.0 0.1 GO:0086092 regulation of the force of heart contraction by cardiac conduction(GO:0086092)
0.0 0.1 GO:0098582 innate vocalization behavior(GO:0098582)
0.0 0.2 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.0 0.2 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.3 GO:1990035 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 0.1 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 0.2 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.3 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.0 0.1 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.0 0.1 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.0 0.8 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.3 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.0 0.1 GO:0014805 smooth muscle adaptation(GO:0014805)
0.0 0.1 GO:0098886 modification of dendritic spine(GO:0098886)
0.0 0.1 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.1 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.2 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.0 0.1 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.1 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.0 0.1 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.0 0.6 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.2 GO:0010820 positive regulation of T cell chemotaxis(GO:0010820)
0.0 0.3 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.2 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.2 GO:0060700 regulation of ribonuclease activity(GO:0060700)
0.0 0.1 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.0 0.2 GO:0018406 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.1 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.1 GO:0034721 histone H3-K4 demethylation, trimethyl-H3-K4-specific(GO:0034721)
0.0 0.1 GO:2000481 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377) positive regulation of cAMP-dependent protein kinase activity(GO:2000481)
0.0 0.1 GO:0061552 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) renal artery morphogenesis(GO:0061441) ganglion morphogenesis(GO:0061552) endothelial tip cell fate specification(GO:0097102) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.0 0.7 GO:0035116 embryonic hindlimb morphogenesis(GO:0035116)
0.0 0.1 GO:0043353 slow-twitch skeletal muscle fiber contraction(GO:0031444) enucleate erythrocyte differentiation(GO:0043353)
0.0 0.1 GO:0060482 lung goblet cell differentiation(GO:0060480) lobar bronchus epithelium development(GO:0060481) lobar bronchus development(GO:0060482)
0.0 0.6 GO:0032506 cytokinetic process(GO:0032506)
0.0 0.1 GO:1903028 positive regulation of opsonization(GO:1903028)
0.0 0.1 GO:0001079 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.0 0.1 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
0.0 0.1 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.0 0.1 GO:1901526 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.0 0.2 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.3 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.0 0.0 GO:0002326 B cell lineage commitment(GO:0002326)
0.0 0.1 GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912)
0.0 0.5 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.3 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.0 0.1 GO:0016139 glycoside catabolic process(GO:0016139) glycosylceramide catabolic process(GO:0046477)
0.0 0.4 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.3 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 0.1 GO:0035262 gonad morphogenesis(GO:0035262)
0.0 0.4 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.1 GO:0006540 glutamate decarboxylation to succinate(GO:0006540)
0.0 0.1 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.0 0.1 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.0 0.1 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.0 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.0 0.3 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.0 0.2 GO:0044351 macropinocytosis(GO:0044351)
0.0 0.2 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 0.1 GO:0021563 glossopharyngeal nerve development(GO:0021563)
0.0 0.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.1 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.0 0.1 GO:0002763 positive regulation of myeloid leukocyte differentiation(GO:0002763)
0.0 0.2 GO:0015866 ADP transport(GO:0015866)
0.0 0.1 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.1 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.0 0.2 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0 0.0 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.1 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.0 0.1 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 0.4 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.0 0.0 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.0 0.3 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.0 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659)
0.0 0.1 GO:0016574 histone ubiquitination(GO:0016574)
0.0 0.0 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 0.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 5.5 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.1 0.3 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.2 GO:0097209 epidermal lamellar body(GO:0097209)
0.1 0.5 GO:1990393 3M complex(GO:1990393)
0.1 0.3 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
0.1 0.4 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 0.2 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1 0.4 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.4 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.6 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 0.4 GO:0070695 FHF complex(GO:0070695)
0.0 0.3 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.1 GO:0097444 spine apparatus(GO:0097444)
0.0 0.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.1 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.0 0.2 GO:0031905 early endosome lumen(GO:0031905)
0.0 0.1 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.0 0.2 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.2 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.1 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.0 0.1 GO:0005584 collagen type I trimer(GO:0005584)
0.0 0.1 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.4 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.8 GO:0031105 septin complex(GO:0031105)
0.0 0.1 GO:0031523 Myb complex(GO:0031523)
0.0 0.1 GO:0031673 H zone(GO:0031673)
0.0 0.2 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.1 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.3 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.2 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.4 GO:0005915 zonula adherens(GO:0005915)
0.0 0.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.7 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.2 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.1 GO:0070435 Shc-EGFR complex(GO:0070435)
0.0 0.4 GO:0010369 chromocenter(GO:0010369)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.9 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.4 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.1 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.0 0.1 GO:0070852 cell body fiber(GO:0070852)
0.0 0.1 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.2 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.4 GO:0034706 sodium channel complex(GO:0034706)
0.0 0.0 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.4 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.1 GO:0042383 sarcolemma(GO:0042383)
0.0 0.2 GO:0030478 actin cap(GO:0030478)
0.0 0.0 GO:0097635 extrinsic component of autophagosome membrane(GO:0097635)
0.0 0.1 GO:0000835 ER ubiquitin ligase complex(GO:0000835)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.1 0.4 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1 0.8 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.1 5.3 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 0.7 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.1 0.3 GO:0003826 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.1 0.4 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
0.1 0.4 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 0.3 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 0.5 GO:0016403 dimethylargininase activity(GO:0016403)
0.1 0.2 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.1 0.2 GO:0003968 RNA-directed RNA polymerase activity(GO:0003968)
0.1 0.8 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 0.6 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.2 GO:0035034 histone acetyltransferase regulator activity(GO:0035034)
0.1 0.4 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.1 0.2 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) DNA/RNA helicase activity(GO:0033677)
0.1 0.2 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.1 0.2 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.1 0.2 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.1 0.2 GO:0034040 lipid-transporting ATPase activity(GO:0034040)
0.1 0.2 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.1 0.3 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.0 0.4 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.7 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.5 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.1 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165) hepoxilin-epoxide hydrolase activity(GO:0047977)
0.0 0.1 GO:0035248 alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248)
0.0 0.9 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.2 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.1 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0 0.2 GO:0005018 platelet-derived growth factor alpha-receptor activity(GO:0005018)
0.0 0.2 GO:0035651 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.0 0.2 GO:0005124 scavenger receptor binding(GO:0005124)
0.0 0.1 GO:0045485 omega-6 fatty acid desaturase activity(GO:0045485)
0.0 0.1 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.0 0.3 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.3 GO:0008047 enzyme activator activity(GO:0008047)
0.0 0.2 GO:0015234 thiamine transmembrane transporter activity(GO:0015234) azole transmembrane transporter activity(GO:1901474)
0.0 0.2 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.0 0.8 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.1 GO:0086040 sodium:proton antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086040)
0.0 0.4 GO:0016889 endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.0 0.1 GO:0008112 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.0 0.2 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.0 1.0 GO:0017166 vinculin binding(GO:0017166)
0.0 0.2 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 0.7 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.1 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.2 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.2 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.1 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.4 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.3 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.0 0.3 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.1 GO:0071566 UFM1 activating enzyme activity(GO:0071566)
0.0 0.3 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 0.4 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.3 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.1 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.0 0.4 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.2 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.1 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 0.1 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.0 0.1 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.1 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.1 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.0 0.2 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 0.1 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.1 GO:0003774 motor activity(GO:0003774)
0.0 0.6 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.8 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.1 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.3 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.1 GO:0016936 galactoside binding(GO:0016936)
0.0 0.0 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.0 0.2 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.0 0.2 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.1 GO:0019770 IgG receptor activity(GO:0019770)
0.0 0.3 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.4 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.2 GO:0045159 myosin II binding(GO:0045159)
0.0 0.1 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.2 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.2 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 0.0 GO:0016652 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.0 0.1 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.2 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.2 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.1 GO:0000976 transcription regulatory region sequence-specific DNA binding(GO:0000976)
0.0 0.3 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.4 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.0 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.0 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.0 0.4 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.1 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.1 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.2 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.1 GO:0070051 fibrinogen binding(GO:0070051)
0.0 0.3 GO:0017049 GTP-Rho binding(GO:0017049)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.4 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.0 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.4 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.6 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.7 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.1 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.6 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.5 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.6 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.6 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.3 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.1 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.6 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.5 REACTOME CELL CELL JUNCTION ORGANIZATION Genes involved in Cell-cell junction organization
0.0 0.3 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.6 REACTOME MYOGENESIS Genes involved in Myogenesis