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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for FOXK1_FOXP2_FOXB1_FOXP3

Z-value: 0.68

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Transcription factors associated with FOXK1_FOXP2_FOXB1_FOXP3

Gene Symbol Gene ID Gene Info
ENSG00000164916.9 forkhead box K1
ENSG00000128573.18 forkhead box P2
ENSG00000171956.5 forkhead box B1
ENSG00000049768.10 forkhead box P3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOXP2hg19_v2_chr7_+_114055052_114055378-0.928.2e-02Click!
FOXP3hg19_v2_chrX_-_49121165_491212880.782.2e-01Click!
FOXK1hg19_v2_chr7_+_4721885_4721945-0.029.8e-01Click!

Activity profile of FOXK1_FOXP2_FOXB1_FOXP3 motif

Sorted Z-values of FOXK1_FOXP2_FOXB1_FOXP3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_76871883 0.56 ENST00000599764.1
Uncharacterized protein
chr17_+_9745786 0.55 ENST00000304773.5
glucagon-like peptide 2 receptor
chr15_+_101417919 0.53 ENST00000561338.1
aldehyde dehydrogenase 1 family, member A3
chr16_+_53242350 0.48 ENST00000565442.1
chromodomain helicase DNA binding protein 9
chr12_-_12714025 0.47 ENST00000539940.1
dual specificity phosphatase 16
chr18_-_2982869 0.43 ENST00000584915.1
lipin 2
chr2_+_149402989 0.38 ENST00000397424.2
enhancer of polycomb homolog 2 (Drosophila)
chr12_-_12714006 0.38 ENST00000541207.1
dual specificity phosphatase 16
chr6_-_131211534 0.38 ENST00000456097.2
erythrocyte membrane protein band 4.1-like 2
chr1_-_54405773 0.34 ENST00000371376.1
heat shock protein family B (small), member 11
chr2_+_177502438 0.33 ENST00000443670.1
long intergenic non-protein coding RNA 1117
chr1_+_246729815 0.32 ENST00000366511.1
consortin, connexin sorting protein
chr14_+_21566980 0.31 ENST00000418511.2
ENST00000554329.2
transmembrane protein 253
chr7_+_91570240 0.31 ENST00000394564.1
A kinase (PRKA) anchor protein 9
chr8_+_97773202 0.31 ENST00000519484.1
carboxypeptidase Q
chr17_-_64216748 0.31 ENST00000585162.1
apolipoprotein H (beta-2-glycoprotein I)
chr1_-_12679171 0.30 ENST00000606790.1
RP11-474O21.5
chr4_-_76008706 0.30 ENST00000562355.1
ENST00000563602.1
RP11-44F21.5
chr1_-_160231451 0.29 ENST00000495887.1
DDB1 and CUL4 associated factor 8
chr14_+_58894404 0.28 ENST00000554463.1
ENST00000555833.1
KIAA0586
chr6_-_32122106 0.28 ENST00000428778.1
proline-rich transmembrane protein 1
chr4_+_183370146 0.27 ENST00000510504.1
teneurin transmembrane protein 3
chr9_-_4859260 0.26 ENST00000599351.1
HCG2011465; Uncharacterized protein
chr10_+_43932553 0.26 ENST00000456416.1
ENST00000437590.2
ENST00000451167.1
zinc finger protein 487
chr8_+_97773457 0.26 ENST00000521142.1
carboxypeptidase Q
chr1_-_168464875 0.26 ENST00000422253.1
RP5-968D22.3
chr11_+_117198801 0.25 ENST00000527609.1
ENST00000533570.1
centrosomal protein 164kDa
chr9_-_20382446 0.24 ENST00000380321.1
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr3_-_129375556 0.22 ENST00000510323.1
transmembrane and coiled-coil domain family 1
chr15_+_42565393 0.22 ENST00000561871.1
glucosidase, alpha; neutral C
chr5_-_38557561 0.21 ENST00000511561.1
leukemia inhibitory factor receptor alpha
chr1_+_164600184 0.21 ENST00000482110.1
pre-B-cell leukemia homeobox 1
chr17_-_7082668 0.21 ENST00000573083.1
ENST00000574388.1
asialoglycoprotein receptor 1
chr1_-_27816556 0.21 ENST00000536657.1
WAS protein family, member 2
chr1_+_12806141 0.21 ENST00000288048.5
chromosome 1 open reading frame 158
chr16_-_84150410 0.21 ENST00000569907.1
membrane-bound transcription factor peptidase, site 1
chr6_-_56716686 0.21 ENST00000520645.1
dystonin
chr7_-_105332084 0.20 ENST00000472195.1
ataxin 7-like 1
chr4_-_174256276 0.20 ENST00000296503.5
high mobility group box 2
chr6_-_72129806 0.20 ENST00000413945.1
ENST00000602878.1
ENST00000436803.1
ENST00000421704.1
ENST00000441570.1
long intergenic non-protein coding RNA 472
chr5_+_75904918 0.20 ENST00000514001.1
ENST00000396234.3
ENST00000509074.1
IQ motif containing GTPase activating protein 2
chr1_+_92545862 0.20 ENST00000370382.3
ENST00000342818.3
BTB (POZ) domain containing 8
chr12_+_21207503 0.20 ENST00000545916.1
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr14_-_75083313 0.20 ENST00000556652.1
ENST00000555313.1
CTD-2207P18.2
chr12_-_111926342 0.19 ENST00000389154.3
ataxin 2
chr10_-_4720301 0.19 ENST00000449712.1
long intergenic non-protein coding RNA 704
chr10_+_111985837 0.19 ENST00000393134.1
MAX interactor 1, dimerization protein
chrX_+_78003204 0.19 ENST00000435339.3
ENST00000514744.1
lysophosphatidic acid receptor 4
chr1_-_235098935 0.19 ENST00000423175.1
RP11-443B7.1
chr1_-_52520828 0.19 ENST00000610127.1
thioredoxin domain containing 12 (endoplasmic reticulum)
chr5_+_40841410 0.18 ENST00000381677.3
caspase recruitment domain family, member 6
chr5_+_64920543 0.18 ENST00000399438.3
ENST00000510585.2
trafficking protein particle complex 13
CDNA FLJ26957 fis, clone SLV00486; Uncharacterized protein
chr3_+_136649311 0.18 ENST00000469404.1
ENST00000467911.1
NCK adaptor protein 1
chr5_-_98262240 0.18 ENST00000284049.3
chromodomain helicase DNA binding protein 1
chr9_+_131445703 0.17 ENST00000454747.1
SET nuclear oncogene
chr4_+_147096837 0.17 ENST00000296581.5
ENST00000502781.1
LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr4_+_77941685 0.17 ENST00000506731.1
septin 11
chr2_-_202298268 0.17 ENST00000440597.1
trafficking protein, kinesin binding 2
chr15_+_42565464 0.17 ENST00000562170.1
ENST00000562859.1
glucosidase, alpha; neutral C
chr2_+_162087577 0.17 ENST00000439442.1
TRAF family member-associated NFKB activator
chr16_-_87970122 0.17 ENST00000309893.2
carbonic anhydrase VA, mitochondrial
chr2_-_160472952 0.17 ENST00000541068.2
ENST00000355831.2
ENST00000343439.5
ENST00000392782.1
bromodomain adjacent to zinc finger domain, 2B
chr4_+_24661479 0.17 ENST00000569621.1
RP11-496D24.2
chr17_-_36358166 0.16 ENST00000537432.1
TBC1 domain family, member 3
chr8_+_67104323 0.16 ENST00000518412.1
ENST00000518035.1
ENST00000517725.1
long intergenic non-protein coding RNA 967
chr7_-_92146729 0.16 ENST00000541751.1
peroxisomal biogenesis factor 1
chr2_-_87248975 0.16 ENST00000409310.2
ENST00000355705.3
plasminogen-like B1
chr9_+_82267508 0.16 ENST00000490347.1
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr17_+_61151306 0.16 ENST00000580068.1
ENST00000580466.1
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr3_-_71179988 0.16 ENST00000491238.1
forkhead box P1
chr6_-_13290684 0.15 ENST00000606393.1
RP1-257A7.5
chr16_+_2880254 0.15 ENST00000570670.1
zymogen granule protein 16B
chr6_-_56707943 0.15 ENST00000370769.4
ENST00000421834.2
ENST00000312431.6
ENST00000361203.3
ENST00000523817.1
dystonin
chr5_-_95550754 0.15 ENST00000502437.1
RP11-254I22.3
chr7_+_151791074 0.15 ENST00000447796.1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr5_-_159766528 0.15 ENST00000505287.2
cyclin J-like
chr7_+_134576317 0.15 ENST00000424922.1
ENST00000495522.1
caldesmon 1
chr11_+_46402482 0.15 ENST00000441869.1
midkine (neurite growth-promoting factor 2)
chr19_-_5624057 0.15 ENST00000590262.1
scaffold attachment factor B2
chr3_-_57233966 0.15 ENST00000473921.1
ENST00000295934.3
HESX homeobox 1
chr9_-_135819987 0.15 ENST00000298552.3
ENST00000403810.1
tuberous sclerosis 1
chr17_+_79369249 0.15 ENST00000574717.2
Uncharacterized protein
chr14_-_23292596 0.15 ENST00000554741.1
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr17_+_37821593 0.14 ENST00000578283.1
titin-cap
chr17_+_58755184 0.14 ENST00000589222.1
ENST00000407086.3
ENST00000390652.5
breast carcinoma amplified sequence 3
chr7_+_151791037 0.14 ENST00000419245.1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr10_-_4720333 0.14 ENST00000430998.2
long intergenic non-protein coding RNA 704
chr17_-_6947225 0.14 ENST00000574600.1
ENST00000308009.1
ENST00000447225.1
solute carrier family 16, member 11
chr17_+_26662679 0.14 ENST00000578158.1
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr5_-_42811986 0.14 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
selenoprotein P, plasma, 1
chr2_-_176033066 0.14 ENST00000437522.1
activating transcription factor 2
chr7_-_140624499 0.14 ENST00000288602.6
v-raf murine sarcoma viral oncogene homolog B
chr13_-_67802549 0.14 ENST00000328454.5
ENST00000377865.2
protocadherin 9
chr14_-_80678512 0.14 ENST00000553968.1
deiodinase, iodothyronine, type II
chr1_+_84630367 0.14 ENST00000370680.1
protein kinase, cAMP-dependent, catalytic, beta
chr2_-_69180083 0.14 ENST00000328895.4
gastrokine 2
chr5_-_137374288 0.14 ENST00000514310.1
family with sequence similarity 13, member B
chr11_+_10476851 0.14 ENST00000396553.2
adenosine monophosphate deaminase 3
chr8_-_131028782 0.13 ENST00000519020.1
family with sequence similarity 49, member B
chr5_-_142065612 0.13 ENST00000360966.5
ENST00000411960.1
fibroblast growth factor 1 (acidic)
chr10_-_63995871 0.13 ENST00000315289.2
rhotekin 2
chr7_+_134430212 0.13 ENST00000436461.2
caldesmon 1
chr1_-_201096312 0.13 ENST00000449188.2
achaete-scute family bHLH transcription factor 5
chr14_+_70234642 0.13 ENST00000555349.1
ENST00000554021.1
serine/arginine-rich splicing factor 5
chr9_-_14322319 0.13 ENST00000606230.1
nuclear factor I/B
chr9_-_21482312 0.13 ENST00000448696.3
interferon, epsilon
chr3_-_123123407 0.12 ENST00000466617.1
adenylate cyclase 5
chr12_+_54378849 0.12 ENST00000515593.1
homeobox C10
chr7_+_134551583 0.12 ENST00000435928.1
caldesmon 1
chr14_+_56127960 0.12 ENST00000553624.1
kinectin 1 (kinesin receptor)
chr9_-_98269481 0.12 ENST00000418258.1
ENST00000553011.1
ENST00000551845.1
patched 1
chr18_+_9475585 0.12 ENST00000585015.1
ralA binding protein 1
chr1_+_174933899 0.12 ENST00000367688.3
RAB GTPase activating protein 1-like
chr19_-_6057282 0.12 ENST00000592281.1
regulatory factor X, 2 (influences HLA class II expression)
chr17_+_34171081 0.12 ENST00000585577.1
TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
chr9_+_134165195 0.12 ENST00000372261.1
phosphatidic acid phosphatase type 2 domain containing 3
chr14_-_88200641 0.12 ENST00000556168.1
RP11-1152H15.1
chr9_-_15472730 0.12 ENST00000481862.1
PC4 and SFRS1 interacting protein 1
chr13_-_41240717 0.12 ENST00000379561.5
forkhead box O1
chr17_-_65241281 0.12 ENST00000358691.5
ENST00000580168.1
helicase with zinc finger
chr9_-_88896977 0.12 ENST00000311534.6
iron-sulfur cluster assembly 1
chr1_+_200011711 0.12 ENST00000544748.1
nuclear receptor subfamily 5, group A, member 2
chrX_-_54070388 0.12 ENST00000415025.1
PHD finger protein 8
chr4_+_26344754 0.12 ENST00000515573.1
recombination signal binding protein for immunoglobulin kappa J region
chr14_+_21569245 0.12 ENST00000556585.2
transmembrane protein 253
chr1_+_196743943 0.12 ENST00000471440.2
ENST00000391985.3
complement factor H-related 3
chr10_-_14050522 0.11 ENST00000342409.2
FERM domain containing 4A
chr7_+_91570165 0.11 ENST00000356239.3
ENST00000359028.2
ENST00000358100.2
A kinase (PRKA) anchor protein 9
chr15_-_70994612 0.11 ENST00000558758.1
ENST00000379983.2
ENST00000560441.1
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr7_+_134464376 0.11 ENST00000454108.1
ENST00000361675.2
caldesmon 1
chr12_-_49504449 0.11 ENST00000547675.1
limb development membrane protein 1-like
chr5_-_137674000 0.11 ENST00000510119.1
ENST00000513970.1
cell division cycle 25C
chr17_+_76037081 0.11 ENST00000588549.1
trinucleotide repeat containing 6C
chr14_+_51026926 0.11 ENST00000557735.1
atlastin GTPase 1
chr8_+_94752349 0.11 ENST00000391680.1
RBM12B antisense RNA 1
chr18_+_21529811 0.11 ENST00000588004.1
laminin, alpha 3
chr3_-_71114066 0.11 ENST00000485326.2
forkhead box P1
chr3_-_71179699 0.11 ENST00000497355.1
forkhead box P1
chr17_+_15604513 0.11 ENST00000481540.1
Homo sapiens zinc finger protein 286A (ZNF286A), transcript variant 6, mRNA.
chr7_+_28448995 0.11 ENST00000424599.1
cAMP responsive element binding protein 5
chr11_-_115375107 0.11 ENST00000545380.1
ENST00000452722.3
ENST00000537058.1
ENST00000536727.1
ENST00000542447.2
ENST00000331581.6
cell adhesion molecule 1
chr2_-_192016276 0.11 ENST00000413064.1
signal transducer and activator of transcription 4
chr11_+_34643600 0.11 ENST00000530286.1
ENST00000533754.1
ets homologous factor
chr19_-_42916499 0.11 ENST00000601189.1
ENST00000599211.1
lipase, hormone-sensitive
chr5_+_78532003 0.11 ENST00000396137.4
junction mediating and regulatory protein, p53 cofactor
chr3_+_136676707 0.11 ENST00000329582.4
interleukin 20 receptor beta
chr1_-_43282945 0.11 ENST00000537227.1
coiled-coil domain containing 23
chr2_+_170440902 0.11 ENST00000448752.2
ENST00000418888.1
ENST00000414307.1
peptidylprolyl isomerase G (cyclophilin G)
chr1_+_87458692 0.11 ENST00000370548.2
ENST00000356813.4
Heparan sulfate 2-O-sulfotransferase 1
heparan sulfate 2-O-sulfotransferase 1
chr12_-_11002063 0.11 ENST00000544994.1
ENST00000228811.4
ENST00000540107.1
proline rich 4 (lacrimal)
chr8_+_21777243 0.11 ENST00000521303.1
exportin 7
chr6_-_134861089 0.11 ENST00000606039.1
RP11-557H15.4
chr6_-_52859046 0.11 ENST00000457564.1
ENST00000541324.1
ENST00000370960.1
glutathione S-transferase alpha 4
chr2_+_149447783 0.11 ENST00000449013.1
enhancer of polycomb homolog 2 (Drosophila)
chr14_+_102276192 0.11 ENST00000557714.1
protein phosphatase 2, regulatory subunit B', gamma
chr12_-_118796971 0.11 ENST00000542902.1
TAO kinase 3
chr3_-_71632894 0.10 ENST00000493089.1
forkhead box P1
chr4_+_155484103 0.10 ENST00000302068.4
fibrinogen beta chain
chr10_+_24755416 0.10 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
KIAA1217
chr2_+_26785409 0.10 ENST00000329615.3
ENST00000409392.1
chromosome 2 open reading frame 70
chr6_+_21666633 0.10 ENST00000606851.1
cancer susceptibility candidate 15 (non-protein coding)
chr17_-_39183452 0.10 ENST00000361883.5
keratin associated protein 1-5
chr15_-_83240783 0.10 ENST00000568994.1
cytoplasmic polyadenylation element binding protein 1
chr10_-_101841588 0.10 ENST00000370418.3
carboxypeptidase N, polypeptide 1
chr5_-_179045199 0.10 ENST00000523921.1
heterogeneous nuclear ribonucleoprotein H1 (H)
chr4_-_15683230 0.10 ENST00000515679.1
F-box and leucine-rich repeat protein 5
chr5_+_130506629 0.10 ENST00000510516.1
ENST00000507584.1
LYR motif containing 7
chr3_+_138068051 0.10 ENST00000474559.1
muscle RAS oncogene homolog
chr8_+_87111059 0.10 ENST00000285393.3
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
chr4_-_164534657 0.10 ENST00000339875.5
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr6_-_113754604 0.10 ENST00000421737.1
RP1-124C6.1
chr2_+_33661382 0.10 ENST00000402538.3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr15_-_34635314 0.10 ENST00000557912.1
ENST00000328848.4
NOP10 ribonucleoprotein
chr13_+_28712614 0.10 ENST00000380958.3
PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr17_-_49021974 0.10 ENST00000501718.2
RP11-700H6.1
chr2_+_175260514 0.10 ENST00000424069.1
ENST00000427038.1
secernin 3
chr12_-_15374343 0.10 ENST00000256953.2
ENST00000546331.1
RAS-like, estrogen-regulated, growth inhibitor
chr3_-_107777208 0.10 ENST00000398258.3
CD47 molecule
chr3_-_141868293 0.10 ENST00000317104.7
ENST00000494358.1
transcription factor Dp-2 (E2F dimerization partner 2)
chr12_+_121416437 0.10 ENST00000402929.1
ENST00000535955.1
ENST00000538626.1
ENST00000543427.1
HNF1 homeobox A
chr6_-_79944336 0.10 ENST00000344726.5
ENST00000275036.7
high mobility group nucleosomal binding domain 3
chr14_+_32476072 0.10 ENST00000556949.1
Uncharacterized protein
chr5_-_64920115 0.10 ENST00000381018.3
ENST00000274327.7
tripartite motif containing 23
chr1_-_202927388 0.10 ENST00000426229.1
ENST00000367254.3
adiponectin receptor 1
chr5_+_64064748 0.10 ENST00000381070.3
ENST00000508024.1
CWC27 spliceosome-associated protein homolog (S. cerevisiae)
chr12_-_772901 0.09 ENST00000305108.4
ninjurin 2
chr12_+_57810198 0.09 ENST00000598001.1
HCG1818482; Uncharacterized protein
chr10_+_114709999 0.09 ENST00000355995.4
ENST00000545257.1
ENST00000543371.1
ENST00000536810.1
ENST00000355717.4
ENST00000538897.1
ENST00000534894.1
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr14_-_69658127 0.09 ENST00000556182.1
RP11-363J20.1
chr8_+_22414182 0.09 ENST00000524057.1
sorbin and SH3 domain containing 3
chr17_+_73642315 0.09 ENST00000556126.2
small integral membrane protein 6
chr4_+_155484155 0.09 ENST00000509493.1
fibrinogen beta chain
chr4_-_74486217 0.09 ENST00000335049.5
ENST00000307439.5
Ras association (RalGDS/AF-6) domain family member 6
chrX_+_15767971 0.09 ENST00000479740.1
ENST00000454127.2
carbonic anhydrase VB, mitochondrial
chr10_-_99094458 0.09 ENST00000371019.2
frequently rearranged in advanced T-cell lymphomas 2
chr6_+_144665237 0.09 ENST00000421035.2
utrophin
chr16_+_4666475 0.09 ENST00000591895.1
mahogunin ring finger 1, E3 ubiquitin protein ligase
chr17_+_66511540 0.09 ENST00000588188.2
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr17_+_46537697 0.09 ENST00000579972.1
RP11-433M22.2
chr19_+_47538560 0.09 ENST00000439365.2
ENST00000594670.1
neuronal PAS domain protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXK1_FOXP2_FOXB1_FOXP3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0045209 MAPK phosphatase export from nucleus(GO:0045208) MAPK phosphatase export from nucleus, leptomycin B sensitive(GO:0045209)
0.2 0.5 GO:0060166 olfactory pit development(GO:0060166)
0.1 0.6 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1 0.1 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.1 0.3 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.1 0.2 GO:1903674 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.1 0.2 GO:0098939 dendritic transport of mitochondrion(GO:0098939) anterograde dendritic transport of mitochondrion(GO:0098972)
0.1 0.2 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.1 0.4 GO:0051661 maintenance of centrosome location(GO:0051661)
0.0 0.4 GO:0000023 maltose metabolic process(GO:0000023)
0.0 0.2 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.0 0.1 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.0 0.1 GO:0060827 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827) negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.0 0.0 GO:0005985 sucrose metabolic process(GO:0005985)
0.0 0.2 GO:0060151 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.0 0.4 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0 0.3 GO:2000567 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.0 0.2 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.0 0.1 GO:0035623 renal glucose absorption(GO:0035623)
0.0 0.1 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.0 0.1 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0 0.1 GO:0030070 insulin processing(GO:0030070)
0.0 0.3 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.0 0.1 GO:0060139 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.0 0.1 GO:1904586 response to putrescine(GO:1904585) cellular response to putrescine(GO:1904586) hepatocyte dedifferentiation(GO:1990828)
0.0 0.1 GO:0051029 rRNA transport(GO:0051029)
0.0 0.2 GO:1902730 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.1 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 0.1 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.0 0.1 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.0 0.0 GO:2000152 regulation of ubiquitin-specific protease activity(GO:2000152)
0.0 0.3 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.0 GO:1902957 negative regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902957)
0.0 0.7 GO:0006590 thyroid hormone generation(GO:0006590)
0.0 0.1 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.0 0.4 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.0 GO:1904327 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.0 0.2 GO:0051291 protein heterooligomerization(GO:0051291)
0.0 0.2 GO:0006196 AMP catabolic process(GO:0006196)
0.0 0.2 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.1 GO:0010157 response to chlorate(GO:0010157)
0.0 0.1 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.0 0.5 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.1 GO:0086097 renin-angiotensin regulation of aldosterone production(GO:0002018) phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.0 0.1 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.0 0.1 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.0 0.1 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.2 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.1 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764) negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.0 0.2 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.1 GO:0035947 regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter(GO:0035947)
0.0 0.1 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.0 0.1 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 0.1 GO:0071684 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0 0.1 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.1 GO:0043387 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.0 0.1 GO:0030573 bile acid catabolic process(GO:0030573)
0.0 0.1 GO:0001757 somite specification(GO:0001757)
0.0 0.1 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.0 0.1 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.1 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) isoquinoline alkaloid metabolic process(GO:0033076)
0.0 0.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.1 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0 0.1 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.1 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.1 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.0 0.4 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.2 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.0 0.1 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.1 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.0 0.1 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0 0.1 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0 0.3 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.3 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 0.2 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0 0.1 GO:0010193 response to ozone(GO:0010193)
0.0 0.1 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.0 0.2 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.1 GO:1901295 arterial endothelial cell fate commitment(GO:0060844) positive regulation of ephrin receptor signaling pathway(GO:1901189) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.1 GO:0002270 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) T-helper 1 cell activation(GO:0035711) negative regulation of apoptotic cell clearance(GO:2000426)
0.0 0.1 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.4 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.0 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.0 0.1 GO:1904693 midbrain morphogenesis(GO:1904693)
0.0 0.1 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.0 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.0 GO:1904729 regulation of intestinal cholesterol absorption(GO:0030300) regulation of intestinal lipid absorption(GO:1904729)
0.0 0.1 GO:0090294 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.0 0.1 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.1 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.0 0.0 GO:0090288 negative regulation of cellular response to growth factor stimulus(GO:0090288)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.0 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.0 0.3 GO:0097264 self proteolysis(GO:0097264)
0.0 0.0 GO:0014016 neuroblast differentiation(GO:0014016)
0.0 0.0 GO:0070781 response to biotin(GO:0070781)
0.0 0.1 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.0 GO:0045349 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.0 0.0 GO:0034443 regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443)
0.0 0.0 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.0 0.1 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.0 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.0 0.0 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.0 0.0 GO:0060738 epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
0.0 0.7 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 0.1 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0 0.0 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.0 0.1 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.1 GO:0043401 steroid hormone mediated signaling pathway(GO:0043401)
0.0 0.2 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.1 GO:2001153 regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153)
0.0 0.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.0 GO:0008057 eye pigment granule organization(GO:0008057)
0.0 0.0 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 0.1 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.0 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.0 0.1 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.3 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.0 0.0 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.0 0.0 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.0 0.0 GO:0051594 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0 0.1 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.0 0.3 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.1 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.0 0.0 GO:0071048 nuclear mRNA surveillance of spliceosomal pre-mRNA splicing(GO:0071030) nuclear retention of unspliced pre-mRNA at the site of transcription(GO:0071048)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0031673 H zone(GO:0031673)
0.1 0.6 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.2 GO:1990923 PET complex(GO:1990923)
0.0 0.1 GO:1902636 kinociliary basal body(GO:1902636)
0.0 0.5 GO:0030478 actin cap(GO:0030478)
0.0 0.2 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369) beta-catenin-TCF complex(GO:1990907)
0.0 0.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.0 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.5 GO:0008091 spectrin(GO:0008091)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 0.3 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.1 GO:0036457 keratohyalin granule(GO:0036457)
0.0 0.1 GO:0072589 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.3 GO:0031209 SCAR complex(GO:0031209)
0.0 0.1 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.3 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.2 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.1 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.1 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.0 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.0 0.1 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.0 0.1 GO:0000137 Golgi cis cisterna(GO:0000137)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0004967 glucagon receptor activity(GO:0004967)
0.1 0.5 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 0.6 GO:0070573 metallodipeptidase activity(GO:0070573)
0.1 0.2 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.0 0.4 GO:0032450 alpha-1,4-glucosidase activity(GO:0004558) maltose alpha-glucosidase activity(GO:0032450)
0.0 0.1 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 0.1 GO:0004947 bradykinin receptor activity(GO:0004947)
0.0 0.3 GO:0023025 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.0 0.2 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.0 0.5 GO:0042731 PH domain binding(GO:0042731)
0.0 0.6 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.3 GO:0071253 connexin binding(GO:0071253)
0.0 0.1 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.0 0.2 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.7 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.2 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.1 GO:0031711 angiotensin type I receptor activity(GO:0001596) bradykinin receptor binding(GO:0031711)
0.0 0.1 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.0 0.4 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.0 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 0.2 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.1 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.2 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.2 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.1 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.1 GO:0031705 bombesin receptor binding(GO:0031705)
0.0 0.1 GO:0002113 interleukin-33 binding(GO:0002113)
0.0 0.2 GO:0097100 supercoiled DNA binding(GO:0097100)
0.0 0.1 GO:0002046 opsin binding(GO:0002046)
0.0 0.1 GO:0031859 platelet activating factor receptor binding(GO:0031859)
0.0 0.2 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.5 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.3 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.1 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.1 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.3 GO:0060229 lipase activator activity(GO:0060229)
0.0 0.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.0 GO:0000384 first spliceosomal transesterification activity(GO:0000384)
0.0 0.4 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.1 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.0 0.0 GO:0003826 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.0 0.1 GO:0005119 smoothened binding(GO:0005119)
0.0 0.2 GO:0036122 BMP binding(GO:0036122)
0.0 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.1 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.0 GO:0052870 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.0 0.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.1 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.0 0.2 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.0 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.0 GO:0015633 zinc transporting ATPase activity(GO:0015633)
0.0 0.1 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.1 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.5 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.1 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.0 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.0 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.0 0.0 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.0 0.1 GO:0031962 mineralocorticoid receptor binding(GO:0031962)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.1 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.1 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.4 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.4 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 0.6 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 0.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.2 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.1 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants