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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for GCM2

Z-value: 1.17

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Transcription factors associated with GCM2

Gene Symbol Gene ID Gene Info
GCM2
ENSG00000124827.6 glial cells missing transcription factor 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GCM2hg19_v2_chr6_-_10882174_108822740.752.5e-01Click!

Activity profile of GCM2 motif

Sorted Z-values of GCM2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_20878932 0.82 ENST00000332947.4
FAM43B
family with sequence similarity 43, member B
chr2_-_220408260 0.75 ENST00000373891.2
CHPF
chondroitin polymerizing factor
chr2_-_220408430 0.64 ENST00000243776.6
CHPF
chondroitin polymerizing factor
chr17_+_17206635 0.62 ENST00000389022.4
NT5M
5',3'-nucleotidase, mitochondrial
chr16_+_2059872 0.57 ENST00000567649.1
NPW
neuropeptide W
chr8_-_144897138 0.57 ENST00000377533.3
SCRIB
scribbled planar cell polarity protein
chr19_-_19626351 0.55 ENST00000585580.3
TSSK6
testis-specific serine kinase 6
chr8_-_144897549 0.55 ENST00000356994.2
ENST00000320476.3
SCRIB
scribbled planar cell polarity protein
chr19_-_49016847 0.54 ENST00000598924.1
CTC-273B12.10
CTC-273B12.10
chr22_+_19710468 0.54 ENST00000366425.3
GP1BB
glycoprotein Ib (platelet), beta polypeptide
chr7_+_2671663 0.54 ENST00000407643.1
TTYH3
tweety family member 3
chr18_+_3450161 0.53 ENST00000551402.1
ENST00000577543.1
TGIF1
TGFB-induced factor homeobox 1
chr7_+_2671568 0.53 ENST00000258796.7
TTYH3
tweety family member 3
chr14_+_104604916 0.47 ENST00000423312.2
KIF26A
kinesin family member 26A
chrX_-_70288234 0.44 ENST00000276105.3
ENST00000374274.3
SNX12
sorting nexin 12
chr19_-_38878632 0.43 ENST00000586599.1
ENST00000334928.6
ENST00000587676.1
GGN
gametogenetin
chr19_-_37178284 0.43 ENST00000425254.2
ENST00000590952.1
ENST00000433232.1
AC074138.3
AC074138.3
chr9_+_140317802 0.42 ENST00000341349.2
ENST00000392815.2
NOXA1
NADPH oxidase activator 1
chr17_+_7123207 0.41 ENST00000584103.1
ENST00000579886.2
ACADVL
acyl-CoA dehydrogenase, very long chain
chr14_-_21566731 0.40 ENST00000360947.3
ZNF219
zinc finger protein 219
chr8_+_37553261 0.39 ENST00000331569.4
ZNF703
zinc finger protein 703
chr14_-_21567009 0.38 ENST00000556174.1
ENST00000554478.1
ENST00000553980.1
ENST00000421093.2
ZNF219
zinc finger protein 219
chr12_-_50222187 0.38 ENST00000335999.6
NCKAP5L
NCK-associated protein 5-like
chr19_-_51872233 0.38 ENST00000601435.1
ENST00000291715.1
CLDND2
claudin domain containing 2
chr1_+_156105878 0.37 ENST00000508500.1
LMNA
lamin A/C
chr17_+_7358889 0.37 ENST00000575379.1
CHRNB1
cholinergic receptor, nicotinic, beta 1 (muscle)
chr7_+_116139821 0.36 ENST00000393480.2
CAV2
caveolin 2
chr15_+_40731920 0.33 ENST00000561234.1
BAHD1
bromo adjacent homology domain containing 1
chr14_-_24912047 0.33 ENST00000553930.1
SDR39U1
short chain dehydrogenase/reductase family 39U, member 1
chr19_-_41222775 0.33 ENST00000324464.3
ENST00000450541.1
ENST00000594720.1
ADCK4
aarF domain containing kinase 4
chr11_-_117102768 0.33 ENST00000532301.1
PCSK7
proprotein convertase subtilisin/kexin type 7
chr2_+_28615669 0.32 ENST00000379619.1
ENST00000264716.4
FOSL2
FOS-like antigen 2
chr7_-_5463175 0.32 ENST00000399537.4
ENST00000430969.1
TNRC18
trinucleotide repeat containing 18
chr19_+_42829702 0.32 ENST00000334370.4
MEGF8
multiple EGF-like-domains 8
chr3_-_50605077 0.31 ENST00000426034.1
ENST00000441239.1
C3orf18
chromosome 3 open reading frame 18
chr18_+_3449695 0.30 ENST00000343820.5
TGIF1
TGFB-induced factor homeobox 1
chr22_-_20307532 0.30 ENST00000405465.3
ENST00000248879.3
DGCR6L
DiGeorge syndrome critical region gene 6-like
chr2_+_121493717 0.30 ENST00000418323.1
GLI2
GLI family zinc finger 2
chr14_+_24769043 0.30 ENST00000267425.3
ENST00000396802.3
NOP9
NOP9 nucleolar protein
chr11_-_118023594 0.29 ENST00000529878.1
SCN4B
sodium channel, voltage-gated, type IV, beta subunit
chr9_+_135037334 0.29 ENST00000393229.3
ENST00000360670.3
ENST00000393228.4
ENST00000372179.3
NTNG2
netrin G2
chr15_+_40733387 0.29 ENST00000416165.1
BAHD1
bromo adjacent homology domain containing 1
chr2_-_220436248 0.28 ENST00000265318.4
OBSL1
obscurin-like 1
chr6_-_31633624 0.28 ENST00000375895.2
ENST00000375900.4
GPANK1
G patch domain and ankyrin repeats 1
chr22_-_43090992 0.28 ENST00000401850.1
A4GALT
alpha 1,4-galactosyltransferase
chr1_-_159893507 0.28 ENST00000368096.1
TAGLN2
transgelin 2
chr3_-_138553779 0.28 ENST00000461451.1
PIK3CB
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
chr9_+_131873659 0.28 ENST00000452489.2
ENST00000347048.4
ENST00000357197.4
ENST00000445241.1
ENST00000355007.3
ENST00000414331.1
PPP2R4
protein phosphatase 2A activator, regulatory subunit 4
chr17_+_7338737 0.28 ENST00000323206.1
ENST00000396568.1
TMEM102
transmembrane protein 102
chr1_+_156698743 0.27 ENST00000524343.1
RRNAD1
ribosomal RNA adenine dimethylase domain containing 1
chr3_-_50605150 0.27 ENST00000357203.3
C3orf18
chromosome 3 open reading frame 18
chr19_+_36208877 0.26 ENST00000420124.1
ENST00000222270.7
ENST00000341701.1
KMT2B
Histone-lysine N-methyltransferase 2B
chr9_-_140064496 0.25 ENST00000371542.3
LRRC26
leucine rich repeat containing 26
chr16_+_30751953 0.24 ENST00000483578.1
RP11-2C24.4
RP11-2C24.4
chr1_+_895930 0.24 ENST00000338591.3
KLHL17
kelch-like family member 17
chr19_+_6361440 0.23 ENST00000245816.4
CLPP
caseinolytic mitochondrial matrix peptidase proteolytic subunit
chr11_+_64009072 0.23 ENST00000535135.1
ENST00000394540.3
FKBP2
FK506 binding protein 2, 13kDa
chr15_+_89164560 0.23 ENST00000379231.3
ENST00000559528.1
AEN
apoptosis enhancing nuclease
chr15_-_93199069 0.23 ENST00000327355.5
FAM174B
family with sequence similarity 174, member B
chr5_+_159343688 0.23 ENST00000306675.3
ADRA1B
adrenoceptor alpha 1B
chr5_+_139493665 0.23 ENST00000331327.3
PURA
purine-rich element binding protein A
chr7_+_150782945 0.23 ENST00000463381.1
AGAP3
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr14_-_75536182 0.22 ENST00000555463.1
ACYP1
acylphosphatase 1, erythrocyte (common) type
chr19_+_36132631 0.22 ENST00000379026.2
ENST00000379023.4
ENST00000402764.2
ENST00000479824.1
ETV2
ets variant 2
chr2_-_220435963 0.22 ENST00000373876.1
ENST00000404537.1
ENST00000603926.1
ENST00000373873.4
ENST00000289656.3
OBSL1
obscurin-like 1
chr1_+_45274154 0.22 ENST00000450269.1
ENST00000453418.1
ENST00000409335.2
BTBD19
BTB (POZ) domain containing 19
chr1_+_156698708 0.22 ENST00000519086.1
RRNAD1
ribosomal RNA adenine dimethylase domain containing 1
chr19_-_5720248 0.22 ENST00000360614.3
LONP1
lon peptidase 1, mitochondrial
chr17_+_74075263 0.22 ENST00000334586.5
ENST00000392503.2
ZACN
zinc activated ligand-gated ion channel
chr2_+_73114489 0.22 ENST00000234454.5
SPR
sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
chr9_+_139606983 0.21 ENST00000371692.4
FAM69B
family with sequence similarity 69, member B
chrX_-_77225135 0.21 ENST00000458128.1
PGAM4
phosphoglycerate mutase family member 4
chr5_+_176514413 0.21 ENST00000513166.1
FGFR4
fibroblast growth factor receptor 4
chr22_+_37447771 0.21 ENST00000402077.3
ENST00000403888.3
ENST00000456470.1
KCTD17
potassium channel tetramerization domain containing 17
chr6_-_41909191 0.21 ENST00000512426.1
ENST00000372987.4
CCND3
cyclin D3
chr4_-_187112626 0.21 ENST00000596414.1
AC110771.1
Uncharacterized protein
chrX_-_70331298 0.21 ENST00000456850.2
ENST00000473378.1
ENST00000487883.1
ENST00000374202.2
IL2RG
interleukin 2 receptor, gamma
chr2_-_220252068 0.20 ENST00000430206.1
ENST00000429013.1
DNPEP
aspartyl aminopeptidase
chr10_+_102790980 0.20 ENST00000393459.1
ENST00000224807.5
SFXN3
sideroflexin 3
chr5_-_176738883 0.20 ENST00000513169.1
ENST00000423571.2
ENST00000502529.1
ENST00000427908.2
MXD3
MAX dimerization protein 3
chr11_-_73882249 0.20 ENST00000535954.1
C2CD3
C2 calcium-dependent domain containing 3
chr11_+_47279155 0.20 ENST00000444396.1
ENST00000457932.1
ENST00000412937.1
NR1H3
nuclear receptor subfamily 1, group H, member 3
chr22_-_30783356 0.19 ENST00000382363.3
RNF215
ring finger protein 215
chr2_-_27603582 0.19 ENST00000323703.6
ENST00000436006.1
ZNF513
zinc finger protein 513
chr15_-_75248954 0.19 ENST00000499788.2
RPP25
ribonuclease P/MRP 25kDa subunit
chr18_+_55102917 0.19 ENST00000491143.2
ONECUT2
one cut homeobox 2
chr11_+_57435441 0.19 ENST00000528177.1
ZDHHC5
zinc finger, DHHC-type containing 5
chr1_+_156698234 0.19 ENST00000368218.4
ENST00000368216.4
RRNAD1
ribosomal RNA adenine dimethylase domain containing 1
chr11_-_72433346 0.19 ENST00000334211.8
ARAP1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr5_+_177027101 0.18 ENST00000029410.5
ENST00000510761.1
ENST00000505468.1
B4GALT7
xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7
chr15_-_45670717 0.18 ENST00000558163.1
ENST00000558336.1
GATM
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr19_-_14316980 0.18 ENST00000361434.3
ENST00000340736.6
LPHN1
latrophilin 1
chr20_+_44421137 0.18 ENST00000415790.1
DNTTIP1
deoxynucleotidyltransferase, terminal, interacting protein 1
chr10_-_99531709 0.18 ENST00000266066.3
SFRP5
secreted frizzled-related protein 5
chr16_+_69221028 0.18 ENST00000336278.4
SNTB2
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
chr19_+_639895 0.17 ENST00000586042.2
ENST00000215530.5
FGF22
fibroblast growth factor 22
chr19_+_5823813 0.17 ENST00000303212.2
NRTN
neurturin
chr22_-_24181174 0.17 ENST00000318109.7
ENST00000406855.3
ENST00000404056.1
ENST00000476077.1
DERL3
derlin 3
chr3_+_126707437 0.17 ENST00000393409.2
ENST00000251772.4
PLXNA1
plexin A1
chr19_+_2236509 0.17 ENST00000221494.5
SF3A2
splicing factor 3a, subunit 2, 66kDa
chr14_-_24911868 0.17 ENST00000554698.1
SDR39U1
short chain dehydrogenase/reductase family 39U, member 1
chr19_+_41222998 0.16 ENST00000263370.2
ITPKC
inositol-trisphosphate 3-kinase C
chr15_+_89164520 0.16 ENST00000332810.3
AEN
apoptosis enhancing nuclease
chr1_+_155179012 0.16 ENST00000609421.1
MTX1
metaxin 1
chr22_-_31741757 0.16 ENST00000215919.3
PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr10_-_21786179 0.16 ENST00000377113.5
CASC10
cancer susceptibility candidate 10
chr9_-_4741217 0.16 ENST00000447596.4
AK3
adenylate kinase 3
chr11_+_63706444 0.15 ENST00000377793.4
ENST00000456907.2
ENST00000539656.1
NAA40
N(alpha)-acetyltransferase 40, NatD catalytic subunit
chr1_-_27226928 0.15 ENST00000361720.5
GPATCH3
G patch domain containing 3
chr16_-_2059748 0.15 ENST00000562103.1
ENST00000431526.1
ZNF598
zinc finger protein 598
chr17_-_3796334 0.15 ENST00000381771.2
ENST00000348335.2
ENST00000158166.5
CAMKK1
calcium/calmodulin-dependent protein kinase kinase 1, alpha
chr11_+_64001962 0.15 ENST00000309422.2
VEGFB
vascular endothelial growth factor B
chr19_-_2236290 0.15 ENST00000591099.2
ENST00000586608.2
ENST00000326631.2
ENST00000587962.2
PLEKHJ1
pleckstrin homology domain containing, family J member 1
chr14_-_24911448 0.15 ENST00000555355.1
ENST00000553343.1
ENST00000556523.1
ENST00000556249.1
ENST00000538105.2
ENST00000555225.1
SDR39U1
short chain dehydrogenase/reductase family 39U, member 1
chr19_+_19626531 0.15 ENST00000507754.4
NDUFA13
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
chr5_+_82767284 0.15 ENST00000265077.3
VCAN
versican
chr1_-_55352834 0.14 ENST00000371269.3
DHCR24
24-dehydrocholesterol reductase
chr14_+_23352374 0.14 ENST00000267396.4
ENST00000536884.1
REM2
RAS (RAD and GEM)-like GTP binding 2
chr16_-_2059797 0.14 ENST00000563630.1
ZNF598
zinc finger protein 598
chr19_-_10024496 0.14 ENST00000593091.1
OLFM2
olfactomedin 2
chr5_+_82767583 0.13 ENST00000512590.2
ENST00000513960.1
ENST00000513984.1
ENST00000502527.2
VCAN
versican
chr2_-_160472952 0.13 ENST00000541068.2
ENST00000355831.2
ENST00000343439.5
ENST00000392782.1
BAZ2B
bromodomain adjacent to zinc finger domain, 2B
chrX_+_120181457 0.13 ENST00000328078.1
GLUD2
glutamate dehydrogenase 2
chr6_+_7108210 0.13 ENST00000467782.1
ENST00000334984.6
ENST00000349384.6
RREB1
ras responsive element binding protein 1
chr17_-_42907564 0.13 ENST00000592524.1
GJC1
gap junction protein, gamma 1, 45kDa
chr14_-_24911971 0.13 ENST00000555365.1
ENST00000399395.3
SDR39U1
short chain dehydrogenase/reductase family 39U, member 1
chr19_-_2236246 0.13 ENST00000587394.2
PLEKHJ1
pleckstrin homology domain containing, family J member 1
chr17_-_27467418 0.13 ENST00000528564.1
MYO18A
myosin XVIIIA
chr11_+_92085262 0.12 ENST00000298047.6
ENST00000409404.2
ENST00000541502.1
FAT3
FAT atypical cadherin 3
chr6_+_7107830 0.12 ENST00000379933.3
RREB1
ras responsive element binding protein 1
chr14_-_64971288 0.12 ENST00000394715.1
ZBTB25
zinc finger and BTB domain containing 25
chr15_+_101389945 0.12 ENST00000561231.1
ENST00000559331.1
ENST00000558254.1
RP11-66B24.2
RP11-66B24.2
chr17_+_79989500 0.12 ENST00000306897.4
RAC3
ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chr2_-_26569611 0.12 ENST00000541401.1
ENST00000433584.1
ENST00000333478.6
GPR113
G protein-coupled receptor 113
chr19_+_35491174 0.12 ENST00000317991.5
ENST00000504615.2
GRAMD1A
GRAM domain containing 1A
chr2_-_19558373 0.12 ENST00000272223.2
OSR1
odd-skipped related transciption factor 1
chr19_-_42758040 0.12 ENST00000593944.1
ERF
Ets2 repressor factor
chr2_+_220408724 0.11 ENST00000421791.1
ENST00000373883.3
ENST00000451952.1
TMEM198
transmembrane protein 198
chr20_-_30795511 0.11 ENST00000246229.4
PLAGL2
pleiomorphic adenoma gene-like 2
chr19_-_39360561 0.11 ENST00000593809.1
ENST00000593424.1
RINL
Ras and Rab interactor-like
chr17_-_16472483 0.10 ENST00000395824.1
ENST00000448349.2
ENST00000395825.3
ZNF287
zinc finger protein 287
chr19_+_17581253 0.10 ENST00000252595.7
ENST00000598424.1
SLC27A1
solute carrier family 27 (fatty acid transporter), member 1
chr19_+_6361754 0.10 ENST00000597326.1
CLPP
caseinolytic mitochondrial matrix peptidase proteolytic subunit
chr5_+_82767487 0.10 ENST00000343200.5
ENST00000342785.4
VCAN
versican
chr5_-_32313082 0.10 ENST00000382142.3
MTMR12
myotubularin related protein 12
chr1_+_28199047 0.10 ENST00000373925.1
ENST00000328928.7
ENST00000373927.3
ENST00000427466.1
ENST00000442118.1
ENST00000373921.3
THEMIS2
thymocyte selection associated family member 2
chr6_+_7107999 0.10 ENST00000491191.1
ENST00000379938.2
ENST00000471433.1
RREB1
ras responsive element binding protein 1
chr5_+_137774706 0.09 ENST00000378339.2
ENST00000254901.5
ENST00000506158.1
REEP2
receptor accessory protein 2
chr1_+_61548225 0.09 ENST00000371187.3
NFIA
nuclear factor I/A
chr1_+_17944832 0.09 ENST00000167825.4
ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr20_-_44420507 0.09 ENST00000243938.4
WFDC3
WAP four-disulfide core domain 3
chr3_-_121740969 0.09 ENST00000393631.1
ENST00000273691.3
ENST00000344209.5
ILDR1
immunoglobulin-like domain containing receptor 1
chr2_-_190446738 0.09 ENST00000427419.1
ENST00000455320.1
SLC40A1
solute carrier family 40 (iron-regulated transporter), member 1
chr7_+_12726623 0.09 ENST00000439721.1
ARL4A
ADP-ribosylation factor-like 4A
chr9_+_79634571 0.09 ENST00000376708.1
FOXB2
forkhead box B2
chr16_-_755819 0.09 ENST00000397621.1
FBXL16
F-box and leucine-rich repeat protein 16
chr1_+_17944806 0.08 ENST00000375408.3
ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr7_+_37960163 0.08 ENST00000199448.4
ENST00000559325.1
ENST00000423717.1
EPDR1
ependymin related 1
chr17_+_53342311 0.08 ENST00000226067.5
HLF
hepatic leukemia factor
chr7_+_150811705 0.08 ENST00000335367.3
AGAP3
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr12_+_56360550 0.08 ENST00000266970.4
CDK2
cyclin-dependent kinase 2
chr19_+_19496624 0.08 ENST00000494516.2
ENST00000360315.3
ENST00000252577.5
GATAD2A
GATA zinc finger domain containing 2A
chr8_+_42873548 0.08 ENST00000533338.1
ENST00000534420.1
HOOK3
RP11-598P20.5
hook microtubule-tethering protein 3
Uncharacterized protein
chr5_+_176513868 0.08 ENST00000292408.4
FGFR4
fibroblast growth factor receptor 4
chr15_-_88799384 0.07 ENST00000540489.2
ENST00000557856.1
ENST00000558676.1
NTRK3
neurotrophic tyrosine kinase, receptor, type 3
chr1_-_156698181 0.07 ENST00000313146.6
ISG20L2
interferon stimulated exonuclease gene 20kDa-like 2
chr5_+_140743859 0.07 ENST00000518069.1
PCDHGA5
protocadherin gamma subfamily A, 5
chr19_+_14142535 0.07 ENST00000263379.2
IL27RA
interleukin 27 receptor, alpha
chr11_+_66036004 0.07 ENST00000311481.6
ENST00000527397.1
RAB1B
RAB1B, member RAS oncogene family
chr3_+_30647994 0.07 ENST00000295754.5
TGFBR2
transforming growth factor, beta receptor II (70/80kDa)
chr15_-_41624685 0.07 ENST00000560640.1
ENST00000220514.3
OIP5
Opa interacting protein 5
chr12_+_56390964 0.06 ENST00000356124.4
ENST00000266971.3
ENST00000394115.2
ENST00000547586.1
ENST00000552258.1
ENST00000548274.1
ENST00000546833.1
SUOX
sulfite oxidase
chr3_+_131100515 0.06 ENST00000537561.1
ENST00000359850.3
ENST00000521288.1
ENST00000502852.1
NUDT16
nudix (nucleoside diphosphate linked moiety X)-type motif 16
chr14_+_77648167 0.06 ENST00000554346.1
ENST00000298351.4
TMEM63C
transmembrane protein 63C
chr7_-_44365216 0.06 ENST00000358707.3
ENST00000457475.1
ENST00000440254.2
CAMK2B
calcium/calmodulin-dependent protein kinase II beta
chr11_+_76777979 0.06 ENST00000531028.1
ENST00000278559.3
ENST00000527066.1
ENST00000529629.1
CAPN5
calpain 5
chr17_-_46703826 0.06 ENST00000550387.1
ENST00000311177.5
HOXB9
homeobox B9
chr15_-_41408409 0.06 ENST00000361937.3
INO80
INO80 complex subunit
chr19_+_6361841 0.06 ENST00000596605.1
CLPP
caseinolytic mitochondrial matrix peptidase proteolytic subunit
chr19_+_41036371 0.06 ENST00000392023.1
SPTBN4
spectrin, beta, non-erythrocytic 4
chr17_-_44270133 0.06 ENST00000262419.6
ENST00000393476.3
KANSL1
KAT8 regulatory NSL complex subunit 1
chr13_-_47471155 0.06 ENST00000543956.1
ENST00000542664.1
HTR2A
5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
chr15_-_45670924 0.05 ENST00000396659.3
GATM
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr5_-_32313019 0.05 ENST00000280285.5
ENST00000264934.5
MTMR12
myotubularin related protein 12
chr1_+_44444865 0.05 ENST00000372324.1
B4GALT2
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
chr13_-_45010939 0.05 ENST00000261489.2
TSC22D1
TSC22 domain family, member 1
chr11_-_61197480 0.05 ENST00000439958.3
ENST00000394888.4
CPSF7
cleavage and polyadenylation specific factor 7, 59kDa
chr14_+_21566980 0.05 ENST00000418511.2
ENST00000554329.2
TMEM253
transmembrane protein 253
chr16_+_30759700 0.05 ENST00000328273.7
PHKG2
phosphorylase kinase, gamma 2 (testis)
chr2_-_220252530 0.05 ENST00000521459.1
DNPEP
aspartyl aminopeptidase
chr16_+_24857309 0.05 ENST00000565769.1
ENST00000449109.2
ENST00000424767.2
ENST00000545376.1
ENST00000569520.1
SLC5A11
solute carrier family 5 (sodium/inositol cotransporter), member 11
chr10_-_70092671 0.05 ENST00000358769.2
ENST00000432941.1
ENST00000495025.2
PBLD
phenazine biosynthesis-like protein domain containing
chr17_-_7218631 0.05 ENST00000577040.2
ENST00000389167.5
ENST00000391950.3
GPS2
G protein pathway suppressor 2
chr12_+_124069070 0.05 ENST00000262225.3
ENST00000438031.2
TMED2
transmembrane emp24 domain trafficking protein 2
chr19_+_51293672 0.05 ENST00000270593.1
ENST00000270594.3
ACPT
acid phosphatase, testicular
chr11_+_47279248 0.05 ENST00000449369.1
NR1H3
nuclear receptor subfamily 1, group H, member 3
chr16_+_30759563 0.04 ENST00000563588.1
ENST00000565924.1
ENST00000424889.3
PHKG2
phosphorylase kinase, gamma 2 (testis)
chr17_-_44270270 0.04 ENST00000572904.1
KANSL1
KAT8 regulatory NSL complex subunit 1
chr14_+_92980111 0.04 ENST00000216487.7
ENST00000557762.1
RIN3
Ras and Rab interactor 3
chr11_+_73882144 0.04 ENST00000328257.8
PPME1
protein phosphatase methylesterase 1

Network of associatons between targets according to the STRING database.

First level regulatory network of GCM2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0098968 neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
0.1 0.5 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.1 0.3 GO:0021775 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.1 0.4 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.1 0.3 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.1 0.2 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.1 0.2 GO:0060796 regulation of transcription involved in primary germ layer cell fate commitment(GO:0060796)
0.1 0.4 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.1 0.4 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.1 0.3 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.1 0.2 GO:0070407 oxidation-dependent protein catabolic process(GO:0070407)
0.1 0.9 GO:0031507 heterochromatin assembly(GO:0031507)
0.1 0.6 GO:0046078 dUMP metabolic process(GO:0046078)
0.1 0.2 GO:0006601 creatine biosynthetic process(GO:0006601)
0.1 0.2 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.2 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.0 0.1 GO:0086021 SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021)
0.0 0.3 GO:1903412 response to bile acid(GO:1903412)
0.0 0.1 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 0.3 GO:0001575 globoside metabolic process(GO:0001575)
0.0 0.6 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 0.3 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.0 0.5 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 1.8 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.3 GO:0010820 positive regulation of T cell chemotaxis(GO:0010820)
0.0 0.1 GO:0007231 osmosensory signaling pathway(GO:0007231) proximal/distal pattern formation involved in nephron development(GO:0072047) specification of nephron tubule identity(GO:0072081) mesonephric duct morphogenesis(GO:0072180) pattern specification involved in metanephros development(GO:0072268)
0.0 0.1 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.0 0.2 GO:0021997 neural plate axis specification(GO:0021997)
0.0 0.4 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.0 0.4 GO:0060263 regulation of respiratory burst(GO:0060263)
0.0 0.1 GO:1903028 positive regulation of opsonization(GO:1903028)
0.0 0.4 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.2 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.0 0.4 GO:0046322 negative regulation of fatty acid oxidation(GO:0046322)
0.0 0.7 GO:0031167 rRNA methylation(GO:0031167)
0.0 0.2 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.0 0.5 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.1 GO:0033490 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.0 0.1 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.1 GO:0002661 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.0 0.2 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0 0.1 GO:0070839 regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395) divalent metal ion export(GO:0070839)
0.0 0.1 GO:0046707 IDP metabolic process(GO:0046707) IDP catabolic process(GO:0046709)
0.0 0.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.2 GO:0035771 interleukin-4-mediated signaling pathway(GO:0035771)
0.0 0.1 GO:0019056 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.0 0.3 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.0 0.1 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.0 0.2 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.1 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.2 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.1 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 0.2 GO:0055072 iron ion homeostasis(GO:0055072)
0.0 0.1 GO:0060161 positive regulation of dopamine receptor signaling pathway(GO:0060161)
0.0 0.3 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.3 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.1 GO:0034378 chylomicron assembly(GO:0034378)
0.0 0.0 GO:0048200 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.2 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.1 GO:0019418 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.1 0.4 GO:0009368 endopeptidase Clp complex(GO:0009368)
0.1 0.5 GO:1990393 3M complex(GO:1990393)
0.1 0.9 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.4 GO:0005638 lamin filament(GO:0005638)
0.0 0.2 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.4 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.2 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.1 GO:0070852 cell body fiber(GO:0070852)
0.0 1.0 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.2 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.2 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 1.4 GO:0032580 Golgi cisterna membrane(GO:0032580)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 0.7 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.1 0.8 GO:0004969 histamine receptor activity(GO:0004969)
0.1 0.2 GO:0015067 amidinotransferase activity(GO:0015067) glycine amidinotransferase activity(GO:0015068)
0.1 0.2 GO:0070361 mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364)
0.1 0.2 GO:0004913 interleukin-4 receptor activity(GO:0004913) interleukin-7 receptor activity(GO:0004917)
0.1 0.2 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 0.2 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.1 0.2 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1 0.4 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0 0.1 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.0 0.2 GO:0031208 POZ domain binding(GO:0031208)
0.0 0.2 GO:0004936 alpha-adrenergic receptor activity(GO:0004936)
0.0 1.1 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.2 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.1 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.2 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.0 0.1 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.0 0.3 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.2 GO:0032810 sterol response element binding(GO:0032810)
0.0 0.6 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.2 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.4 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.5 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.3 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.4 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.9 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.2 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.1 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.0 0.6 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.3 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.1 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.1 GO:0030151 molybdenum ion binding(GO:0030151)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.0 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505) 4-alpha-hydroxytetrahydrobiopterin dehydratase activity(GO:0008124)
0.0 0.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.6 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.2 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 0.5 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.3 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.4 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.8 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.3 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL