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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for GLIS3

Z-value: 0.48

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Transcription factors associated with GLIS3

Gene Symbol Gene ID Gene Info
GLIS3
ENSG00000107249.17 GLIS family zinc finger 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GLIS3hg19_v2_chr9_-_4299874_42999160.963.8e-02Click!

Activity profile of GLIS3 motif

Sorted Z-values of GLIS3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_247095236 0.39 ENST00000478568.1
AHCTF1
AT hook containing transcription factor 1
chr19_-_56092187 0.29 ENST00000325421.4
ENST00000592239.1
ZNF579
zinc finger protein 579
chr11_+_393428 0.26 ENST00000533249.1
ENST00000527442.1
PKP3
plakophilin 3
chr5_-_137090028 0.20 ENST00000314940.4
HNRNPA0
heterogeneous nuclear ribonucleoprotein A0
chr9_+_131904295 0.19 ENST00000434095.1
PPP2R4
protein phosphatase 2A activator, regulatory subunit 4
chr12_+_48152774 0.18 ENST00000549243.1
SLC48A1
solute carrier family 48 (heme transporter), member 1
chr9_+_131903916 0.18 ENST00000419582.1
PPP2R4
protein phosphatase 2A activator, regulatory subunit 4
chr19_-_10613361 0.15 ENST00000591039.1
ENST00000591419.1
KEAP1
kelch-like ECH-associated protein 1
chr11_+_68671310 0.13 ENST00000255078.3
ENST00000539224.1
IGHMBP2
immunoglobulin mu binding protein 2
chr1_+_31886653 0.13 ENST00000536384.1
SERINC2
serine incorporator 2
chr2_+_219824357 0.13 ENST00000302625.4
CDK5R2
cyclin-dependent kinase 5, regulatory subunit 2 (p39)
chr9_+_131904233 0.12 ENST00000432651.1
ENST00000435132.1
PPP2R4
protein phosphatase 2A activator, regulatory subunit 4
chr10_+_71389983 0.12 ENST00000373279.4
C10orf35
chromosome 10 open reading frame 35
chr22_+_50628999 0.11 ENST00000395827.1
TRABD
TraB domain containing
chr7_+_150758304 0.11 ENST00000482950.1
ENST00000463414.1
ENST00000310317.5
SLC4A2
solute carrier family 4 (anion exchanger), member 2
chr17_-_33446820 0.11 ENST00000592577.1
ENST00000590016.1
ENST00000345365.6
ENST00000360276.3
ENST00000357906.3
RAD51D
RAD51 paralog D
chr7_+_150758642 0.10 ENST00000488420.1
SLC4A2
solute carrier family 4 (anion exchanger), member 2
chr17_+_4675175 0.10 ENST00000270560.3
TM4SF5
transmembrane 4 L six family member 5
chr19_-_10613421 0.10 ENST00000393623.2
KEAP1
kelch-like ECH-associated protein 1
chr19_+_40697514 0.10 ENST00000253055.3
MAP3K10
mitogen-activated protein kinase kinase kinase 10
chr11_+_68451943 0.09 ENST00000265643.3
GAL
galanin/GMAP prepropeptide
chr11_-_118789613 0.09 ENST00000532899.1
BCL9L
B-cell CLL/lymphoma 9-like
chr14_+_77228532 0.09 ENST00000167106.4
ENST00000554237.1
VASH1
vasohibin 1
chr20_-_30310693 0.08 ENST00000307677.4
ENST00000420653.1
BCL2L1
BCL2-like 1
chr17_+_46018872 0.08 ENST00000583599.1
ENST00000434554.2
ENST00000225573.4
ENST00000544840.1
ENST00000534893.1
PNPO
pyridoxamine 5'-phosphate oxidase
chr9_-_130742792 0.08 ENST00000373095.1
FAM102A
family with sequence similarity 102, member A
chr9_-_88874519 0.08 ENST00000376001.3
ENST00000339137.3
C9orf153
chromosome 9 open reading frame 153
chr19_-_49828438 0.08 ENST00000454748.3
ENST00000598828.1
ENST00000335875.4
SLC6A16
solute carrier family 6, member 16
chr1_+_33207381 0.07 ENST00000401073.2
KIAA1522
KIAA1522
chr20_-_30310656 0.07 ENST00000376055.4
BCL2L1
BCL2-like 1
chr18_+_3451584 0.07 ENST00000551541.1
TGIF1
TGFB-induced factor homeobox 1
chr19_-_10613862 0.06 ENST00000592055.1
KEAP1
kelch-like ECH-associated protein 1
chr19_+_48828582 0.06 ENST00000270221.6
ENST00000596315.1
EMP3
epithelial membrane protein 3
chr6_+_33172407 0.05 ENST00000374662.3
HSD17B8
hydroxysteroid (17-beta) dehydrogenase 8
chr8_+_11627148 0.05 ENST00000436750.3
NEIL2
nei endonuclease VIII-like 2 (E. coli)
chr16_+_30006615 0.05 ENST00000563197.1
INO80E
INO80 complex subunit E
chr12_+_132312931 0.04 ENST00000360564.1
ENST00000545671.1
ENST00000545790.1
MMP17
matrix metallopeptidase 17 (membrane-inserted)
chr19_+_44488330 0.04 ENST00000591532.1
ENST00000407951.2
ENST00000270014.2
ENST00000590615.1
ENST00000586454.1
ZNF155
zinc finger protein 155
chr5_-_180671172 0.04 ENST00000512805.1
GNB2L1
guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
chr22_-_50964849 0.04 ENST00000543927.1
ENST00000423348.1
SCO2
SCO2 cytochrome c oxidase assembly protein
chr17_-_73178599 0.04 ENST00000578238.1
SUMO2
small ubiquitin-like modifier 2
chr3_-_160167301 0.04 ENST00000494486.1
TRIM59
tripartite motif containing 59
chr22_-_21482352 0.04 ENST00000329949.3
POM121L7
POM121 transmembrane nucleoporin-like 7
chr1_-_157108266 0.04 ENST00000326786.4
ETV3
ets variant 3
chr17_-_79917645 0.04 ENST00000477214.1
NOTUM
notum pectinacetylesterase homolog (Drosophila)
chr22_-_32022280 0.04 ENST00000442379.1
PISD
phosphatidylserine decarboxylase
chr17_+_5389605 0.04 ENST00000576988.1
ENST00000576570.1
ENST00000573759.1
MIS12
MIS12 kinetochore complex component
chr2_-_208030647 0.03 ENST00000309446.6
KLF7
Kruppel-like factor 7 (ubiquitous)
chr6_+_44191290 0.03 ENST00000371755.3
ENST00000371740.5
ENST00000371731.1
ENST00000393841.1
SLC29A1
solute carrier family 29 (equilibrative nucleoside transporter), member 1
chr8_+_11627205 0.03 ENST00000455213.2
ENST00000403422.3
ENST00000528323.1
ENST00000284503.6
NEIL2
nei endonuclease VIII-like 2 (E. coli)
chr8_-_29120580 0.03 ENST00000524189.1
KIF13B
kinesin family member 13B
chr1_-_160254913 0.03 ENST00000440949.3
ENST00000368072.5
ENST00000608310.1
ENST00000556710.1
PEX19
DCAF8
DCAF8
peroxisomal biogenesis factor 19
DDB1 and CUL4 associated factor 8
DDB1- and CUL4-associated factor 8
chr8_+_27183033 0.03 ENST00000420218.2
PTK2B
protein tyrosine kinase 2 beta
chr12_-_57400227 0.03 ENST00000300101.2
ZBTB39
zinc finger and BTB domain containing 39
chr15_+_91478493 0.03 ENST00000418476.2
UNC45A
unc-45 homolog A (C. elegans)
chr19_+_13875316 0.03 ENST00000319545.8
ENST00000593245.1
ENST00000040663.6
MRI1
methylthioribose-1-phosphate isomerase 1
chr20_+_61867235 0.03 ENST00000342412.6
ENST00000217169.3
BIRC7
baculoviral IAP repeat containing 7
chr15_-_43882353 0.03 ENST00000453080.1
ENST00000360301.4
ENST00000360135.4
ENST00000417085.1
ENST00000431962.1
ENST00000334933.4
ENST00000381879.4
ENST00000420765.1
PPIP5K1
diphosphoinositol pentakisphosphate kinase 1
chr22_-_31742218 0.03 ENST00000266269.5
ENST00000405309.3
ENST00000351933.4
PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr3_-_160167508 0.02 ENST00000479460.1
TRIM59
tripartite motif containing 59
chr17_+_7792101 0.02 ENST00000358181.4
ENST00000330494.7
CHD3
chromodomain helicase DNA binding protein 3
chr18_+_3451646 0.02 ENST00000345133.5
ENST00000330513.5
ENST00000549546.1
TGIF1
TGFB-induced factor homeobox 1
chr1_+_110527308 0.02 ENST00000369799.5
AHCYL1
adenosylhomocysteinase-like 1
chr11_-_8680383 0.02 ENST00000299550.6
TRIM66
tripartite motif containing 66
chr17_+_80818231 0.02 ENST00000576996.1
TBCD
tubulin folding cofactor D
chr6_+_24495185 0.02 ENST00000348925.2
ALDH5A1
aldehyde dehydrogenase 5 family, member A1
chr3_+_127348005 0.02 ENST00000342480.6
PODXL2
podocalyxin-like 2
chr22_-_21482046 0.02 ENST00000419447.1
POM121L7
POM121 transmembrane nucleoporin-like 7
chr6_+_24495067 0.02 ENST00000357578.3
ENST00000546278.1
ENST00000491546.1
ALDH5A1
aldehyde dehydrogenase 5 family, member A1
chr19_-_41859814 0.01 ENST00000221930.5
TGFB1
transforming growth factor, beta 1
chr11_+_5646213 0.01 ENST00000429814.2
TRIM34
tripartite motif containing 34
chr20_-_23969416 0.01 ENST00000335694.4
GGTLC1
gamma-glutamyltransferase light chain 1
chr11_+_134855246 0.00 ENST00000597621.1
AP003062.1
CDNA FLJ27342 fis, clone TST02993; Uncharacterized protein
chr11_+_1463728 0.00 ENST00000544817.1
BRSK2
BR serine/threonine kinase 2
chr18_+_11752040 0.00 ENST00000423027.3
GNAL
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr2_+_220379052 0.00 ENST00000347842.3
ENST00000358078.4
ASIC4
acid-sensing (proton-gated) ion channel family member 4
chr19_+_1495362 0.00 ENST00000395479.4
REEP6
receptor accessory protein 6

Network of associatons between targets according to the STRING database.

First level regulatory network of GLIS3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0021718 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.0 0.1 GO:0051795 positive regulation of catagen(GO:0051795)
0.0 0.3 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.1 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.0 0.1 GO:1904222 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0 0.1 GO:0042823 pyridoxal phosphate biosynthetic process(GO:0042823)
0.0 0.3 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.2 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.0 0.4 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.0 GO:1990697 protein depalmitoleylation(GO:1990697)
0.0 0.1 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.2 GO:0015886 heme transport(GO:0015886)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.4 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.1 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.0 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.0 0.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.1 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.1 GO:0047025 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.0 0.1 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.2 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.0 GO:1990699 palmitoleyl hydrolase activity(GO:1990699)
0.0 0.3 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.2 GO:0015232 heme transporter activity(GO:0015232)