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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for IRF7

Z-value: 0.93

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Transcription factors associated with IRF7

Gene Symbol Gene ID Gene Info
IRF7
ENSG00000185507.15 interferon regulatory factor 7

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
IRF7hg19_v2_chr11_-_615942_615999-0.346.6e-01Click!

Activity profile of IRF7 motif

Sorted Z-values of IRF7 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_39759154 0.76 ENST00000331982.5
IFNL2
interferon, lambda 2
chr10_+_91061712 0.56 ENST00000371826.3
IFIT2
interferon-induced protein with tetratricopeptide repeats 2
chr17_-_40264692 0.44 ENST00000591220.1
ENST00000251642.3
DHX58
DEXH (Asp-Glu-X-His) box polypeptide 58
chr19_-_39735646 0.44 ENST00000413851.2
IFNL3
interferon, lambda 3
chr17_-_40264321 0.39 ENST00000430773.1
ENST00000413196.2
DHX58
DEXH (Asp-Glu-X-His) box polypeptide 58
chr2_-_152118276 0.34 ENST00000409092.1
RBM43
RNA binding motif protein 43
chr17_-_67057047 0.31 ENST00000495634.1
ENST00000453985.2
ENST00000585714.1
ABCA9
ATP-binding cassette, sub-family A (ABC1), member 9
chr19_+_39786962 0.31 ENST00000333625.2
IFNL1
interferon, lambda 1
chr10_+_91152303 0.31 ENST00000371804.3
IFIT1
interferon-induced protein with tetratricopeptide repeats 1
chr2_-_231084617 0.30 ENST00000409815.2
SP110
SP110 nuclear body protein
chr3_+_159706537 0.29 ENST00000305579.2
ENST00000480787.1
ENST00000466512.1
IL12A
interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
chr1_-_114429997 0.29 ENST00000471267.1
ENST00000393320.3
BCL2L15
BCL2-like 15
chr1_+_112016414 0.29 ENST00000343534.5
ENST00000369718.3
C1orf162
chromosome 1 open reading frame 162
chr2_-_231084659 0.28 ENST00000258381.6
ENST00000358662.4
ENST00000455674.1
ENST00000392048.3
SP110
SP110 nuclear body protein
chr12_+_43086018 0.26 ENST00000550177.1
RP11-25I15.3
RP11-25I15.3
chr10_+_91092241 0.26 ENST00000371811.4
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr17_-_57229155 0.25 ENST00000584089.1
SKA2
spindle and kinetochore associated complex subunit 2
chr3_-_28390120 0.22 ENST00000334100.6
AZI2
5-azacytidine induced 2
chr12_-_49463620 0.21 ENST00000550675.1
RHEBL1
Ras homolog enriched in brain like 1
chr1_-_150693318 0.21 ENST00000442853.1
ENST00000368995.4
ENST00000368993.2
ENST00000361824.2
ENST00000322343.7
HORMAD1
HORMA domain containing 1
chr21_+_35107346 0.20 ENST00000456489.1
ITSN1
intersectin 1 (SH3 domain protein)
chr1_+_43613612 0.19 ENST00000335282.4
FAM183A
family with sequence similarity 183, member A
chr6_+_116575329 0.19 ENST00000430252.2
ENST00000540275.1
ENST00000448740.2
DSE
RP3-486I3.7
dermatan sulfate epimerase
RP3-486I3.7
chr4_+_103790462 0.19 ENST00000503643.1
CISD2
CDGSH iron sulfur domain 2
chr11_+_34643600 0.19 ENST00000530286.1
ENST00000533754.1
EHF
ets homologous factor
chr1_-_150693305 0.19 ENST00000368987.1
HORMAD1
HORMA domain containing 1
chr7_-_35734176 0.18 ENST00000413517.1
ENST00000438224.1
HERPUD2
HERPUD family member 2
chr2_-_231084820 0.18 ENST00000258382.5
ENST00000338556.3
SP110
SP110 nuclear body protein
chr10_+_91087651 0.18 ENST00000371818.4
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr19_+_49977466 0.18 ENST00000596435.1
ENST00000344019.3
ENST00000597551.1
ENST00000204637.2
ENST00000600429.1
FLT3LG
fms-related tyrosine kinase 3 ligand
chr4_-_14889791 0.17 ENST00000509654.1
ENST00000515031.1
ENST00000505089.2
LINC00504
long intergenic non-protein coding RNA 504
chr22_-_22641542 0.17 ENST00000606654.1
LL22NC03-2H8.5
LL22NC03-2H8.5
chr1_-_114430169 0.17 ENST00000393316.3
BCL2L15
BCL2-like 15
chr10_+_695888 0.17 ENST00000441152.2
PRR26
proline rich 26
chr8_+_93895865 0.17 ENST00000391681.1
AC117834.1
AC117834.1
chr8_+_97597148 0.16 ENST00000521590.1
SDC2
syndecan 2
chr14_+_32798547 0.16 ENST00000557354.1
ENST00000557102.1
ENST00000557272.1
AKAP6
A kinase (PRKA) anchor protein 6
chr4_+_71600144 0.16 ENST00000502653.1
RUFY3
RUN and FYVE domain containing 3
chr9_+_33264861 0.16 ENST00000223500.8
CHMP5
charged multivesicular body protein 5
chr9_+_33265011 0.16 ENST00000419016.2
CHMP5
charged multivesicular body protein 5
chr3_+_57882061 0.16 ENST00000461354.1
ENST00000466255.1
SLMAP
sarcolemma associated protein
chr5_-_154230130 0.16 ENST00000519501.1
ENST00000518651.1
ENST00000517938.1
ENST00000520461.1
FAXDC2
fatty acid hydroxylase domain containing 2
chr16_+_53412368 0.16 ENST00000565189.1
RP11-44F14.2
RP11-44F14.2
chrX_+_51486481 0.15 ENST00000340438.4
GSPT2
G1 to S phase transition 2
chr9_-_21077939 0.15 ENST00000380232.2
IFNB1
interferon, beta 1, fibroblast
chr15_+_35270552 0.15 ENST00000391457.2
AC114546.1
HCG37415; PRO1914; Uncharacterized protein
chr2_+_29001711 0.15 ENST00000418910.1
PPP1CB
protein phosphatase 1, catalytic subunit, beta isozyme
chr11_+_940729 0.15 ENST00000527024.1
AP2A2
adaptor-related protein complex 2, alpha 2 subunit
chr2_-_151344172 0.15 ENST00000375734.2
ENST00000263895.4
ENST00000454202.1
RND3
Rho family GTPase 3
chr13_-_44735393 0.14 ENST00000400419.1
SMIM2
small integral membrane protein 2
chr6_+_160693591 0.14 ENST00000419196.1
RP1-276N6.2
RP1-276N6.2
chr17_+_41363854 0.14 ENST00000588693.1
ENST00000588659.1
ENST00000541594.1
ENST00000536052.1
ENST00000331615.3
TMEM106A
transmembrane protein 106A
chr11_+_7559485 0.14 ENST00000527790.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr15_+_45003675 0.14 ENST00000558401.1
ENST00000559916.1
ENST00000544417.1
B2M
beta-2-microglobulin
chr11_+_17298522 0.14 ENST00000529313.1
NUCB2
nucleobindin 2
chr8_+_26150628 0.14 ENST00000523925.1
ENST00000315985.7
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr12_+_113344582 0.14 ENST00000202917.5
ENST00000445409.2
ENST00000452357.2
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr20_-_56195525 0.14 ENST00000371173.3
ENST00000395822.3
ENST00000340462.4
ENST00000343535.4
ZBP1
Z-DNA binding protein 1
chr10_-_92681033 0.14 ENST00000371697.3
ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr13_+_78109804 0.14 ENST00000535157.1
SCEL
sciellin
chr9_+_74764340 0.14 ENST00000376986.1
ENST00000358399.3
GDA
guanine deaminase
chr1_+_120839412 0.13 ENST00000355228.4
FAM72B
family with sequence similarity 72, member B
chr4_+_142557717 0.13 ENST00000320650.4
ENST00000296545.7
IL15
interleukin 15
chr14_+_58711539 0.13 ENST00000216455.4
ENST00000412908.2
ENST00000557508.1
PSMA3
proteasome (prosome, macropain) subunit, alpha type, 3
chr4_-_170897045 0.13 ENST00000508313.1
RP11-205M3.3
RP11-205M3.3
chr5_-_55777586 0.13 ENST00000506836.1
CTC-236F12.4
Uncharacterized protein
chrX_-_153979315 0.13 ENST00000369575.3
ENST00000369568.4
ENST00000424127.2
GAB3
GRB2-associated binding protein 3
chr18_-_56985873 0.13 ENST00000299721.3
CPLX4
complexin 4
chr5_-_146461027 0.13 ENST00000394410.2
ENST00000508267.1
ENST00000504198.1
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr11_+_17298543 0.13 ENST00000533926.1
NUCB2
nucleobindin 2
chr15_+_86087267 0.13 ENST00000558166.1
AKAP13
A kinase (PRKA) anchor protein 13
chr11_-_104916034 0.13 ENST00000528513.1
ENST00000375706.2
ENST00000375704.3
CARD16
caspase recruitment domain family, member 16
chr1_+_162602244 0.13 ENST00000367922.3
ENST00000367921.3
DDR2
discoidin domain receptor tyrosine kinase 2
chr16_-_67597789 0.13 ENST00000605277.1
CTD-2012K14.6
CTD-2012K14.6
chr16_-_4850471 0.13 ENST00000592019.1
ENST00000586153.1
ROGDI
rogdi homolog (Drosophila)
chr4_+_142557771 0.12 ENST00000514653.1
IL15
interleukin 15
chr10_-_9801179 0.12 ENST00000419836.1
RP5-1051H14.2
RP5-1051H14.2
chr2_-_55237484 0.12 ENST00000394609.2
RTN4
reticulon 4
chr2_-_153032484 0.12 ENST00000263904.4
STAM2
signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
chrX_-_34675391 0.12 ENST00000275954.3
TMEM47
transmembrane protein 47
chr10_+_91174486 0.12 ENST00000416601.1
IFIT5
interferon-induced protein with tetratricopeptide repeats 5
chr9_+_74764278 0.12 ENST00000238018.4
ENST00000376989.3
GDA
guanine deaminase
chr1_+_221054411 0.12 ENST00000427693.1
HLX
H2.0-like homeobox
chr9_-_32526184 0.12 ENST00000545044.1
ENST00000379868.1
DDX58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr16_-_69385681 0.12 ENST00000288025.3
TMED6
transmembrane emp24 protein transport domain containing 6
chr4_-_54457783 0.12 ENST00000263925.7
ENST00000512247.1
LNX1
ligand of numb-protein X 1, E3 ubiquitin protein ligase
chr14_+_35747825 0.12 ENST00000540871.1
PSMA6
proteasome (prosome, macropain) subunit, alpha type, 6
chr15_+_78832747 0.11 ENST00000560217.1
ENST00000044462.7
ENST00000559082.1
ENST00000559948.1
ENST00000413382.2
ENST00000559146.1
ENST00000558281.1
PSMA4
proteasome (prosome, macropain) subunit, alpha type, 4
chr3_-_28390298 0.11 ENST00000457172.1
AZI2
5-azacytidine induced 2
chr3_-_42306248 0.11 ENST00000334681.5
CCK
cholecystokinin
chr9_-_21228221 0.11 ENST00000413767.2
IFNA17
interferon, alpha 17
chr17_+_6659153 0.11 ENST00000441631.1
ENST00000438512.1
ENST00000346752.4
ENST00000361842.3
XAF1
XIAP associated factor 1
chr18_+_3252265 0.11 ENST00000580887.1
ENST00000536605.1
MYL12A
myosin, light chain 12A, regulatory, non-sarcomeric
chr7_-_102985288 0.11 ENST00000379263.3
DNAJC2
DnaJ (Hsp40) homolog, subfamily C, member 2
chr7_-_102985035 0.11 ENST00000426036.2
ENST00000249270.7
ENST00000454277.1
ENST00000412522.1
DNAJC2
DnaJ (Hsp40) homolog, subfamily C, member 2
chr5_+_34915444 0.11 ENST00000336767.5
BRIX1
BRX1, biogenesis of ribosomes, homolog (S. cerevisiae)
chr2_-_37899323 0.11 ENST00000295324.3
ENST00000457889.1
CDC42EP3
CDC42 effector protein (Rho GTPase binding) 3
chr3_+_137906154 0.11 ENST00000466749.1
ENST00000358441.2
ENST00000489213.1
ARMC8
armadillo repeat containing 8
chr15_+_49715293 0.11 ENST00000267843.4
ENST00000560270.1
FGF7
fibroblast growth factor 7
chr6_+_148593425 0.11 ENST00000367469.1
SASH1
SAM and SH3 domain containing 1
chr1_+_158979792 0.11 ENST00000359709.3
ENST00000430894.2
IFI16
interferon, gamma-inducible protein 16
chr15_-_80263506 0.11 ENST00000335661.6
BCL2A1
BCL2-related protein A1
chr19_-_44171817 0.11 ENST00000593714.1
PLAUR
plasminogen activator, urokinase receptor
chr12_-_50616382 0.11 ENST00000552783.1
LIMA1
LIM domain and actin binding 1
chr6_-_35888905 0.10 ENST00000510290.1
ENST00000423325.2
ENST00000373822.1
SRPK1
SRSF protein kinase 1
chr6_-_138866823 0.10 ENST00000342260.5
NHSL1
NHS-like 1
chr15_+_49715449 0.10 ENST00000560979.1
FGF7
fibroblast growth factor 7
chr12_-_26278030 0.10 ENST00000242728.4
BHLHE41
basic helix-loop-helix family, member e41
chr11_+_46402583 0.10 ENST00000359803.3
MDK
midkine (neurite growth-promoting factor 2)
chr14_+_24605389 0.10 ENST00000382708.3
ENST00000561435.1
PSME1
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr17_+_76311791 0.10 ENST00000586321.1
AC061992.2
AC061992.2
chr6_+_13182751 0.10 ENST00000415087.1
PHACTR1
phosphatase and actin regulator 1
chr7_+_74188309 0.10 ENST00000289473.4
ENST00000433458.1
NCF1
neutrophil cytosolic factor 1
chr8_+_97657531 0.10 ENST00000519900.1
ENST00000517742.1
CPQ
carboxypeptidase Q
chr9_+_5450503 0.10 ENST00000381573.4
ENST00000381577.3
CD274
CD274 molecule
chr3_-_28390415 0.10 ENST00000414162.1
ENST00000420543.2
AZI2
5-azacytidine induced 2
chr6_+_122931366 0.10 ENST00000368452.2
ENST00000368448.1
ENST00000392490.1
PKIB
protein kinase (cAMP-dependent, catalytic) inhibitor beta
chr14_-_74296806 0.10 ENST00000555539.1
RP5-1021I20.2
RP5-1021I20.2
chr15_+_31196080 0.10 ENST00000561607.1
ENST00000565466.1
FAN1
FANCD2/FANCI-associated nuclease 1
chrX_+_23682379 0.10 ENST00000379349.1
PRDX4
peroxiredoxin 4
chr5_-_87980587 0.10 ENST00000509783.1
ENST00000509405.1
ENST00000506978.1
ENST00000509265.1
ENST00000513805.1
LINC00461
long intergenic non-protein coding RNA 461
chr2_-_163175133 0.10 ENST00000421365.2
ENST00000263642.2
IFIH1
interferon induced with helicase C domain 1
chr19_-_53466095 0.10 ENST00000391786.2
ENST00000434371.2
ENST00000357666.4
ENST00000438970.2
ENST00000270457.4
ENST00000535506.1
ENST00000444460.2
ENST00000457013.2
ZNF816
zinc finger protein 816
chr3_+_141106643 0.10 ENST00000514251.1
ZBTB38
zinc finger and BTB domain containing 38
chr14_+_37126765 0.10 ENST00000402703.2
PAX9
paired box 9
chr2_-_7005785 0.09 ENST00000256722.5
ENST00000404168.1
ENST00000458098.1
CMPK2
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr14_+_24605361 0.09 ENST00000206451.6
ENST00000559123.1
PSME1
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr8_-_56986768 0.09 ENST00000523936.1
RPS20
ribosomal protein S20
chr8_+_95835438 0.09 ENST00000521860.1
ENST00000519457.1
ENST00000519053.1
ENST00000523731.1
ENST00000447247.1
INTS8
integrator complex subunit 8
chr4_-_169401628 0.09 ENST00000514748.1
ENST00000512371.1
ENST00000260184.7
ENST00000505890.1
ENST00000511577.1
DDX60L
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like
chr17_-_65362678 0.09 ENST00000357146.4
ENST00000356126.3
PSMD12
proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
chrX_+_80457442 0.09 ENST00000373212.5
SH3BGRL
SH3 domain binding glutamic acid-rich protein like
chr18_+_61575200 0.09 ENST00000238508.3
SERPINB10
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr14_-_35099377 0.09 ENST00000362031.4
SNX6
sorting nexin 6
chr5_+_82373317 0.09 ENST00000282268.3
ENST00000338635.6
XRCC4
X-ray repair complementing defective repair in Chinese hamster cells 4
chr6_-_138833630 0.09 ENST00000533765.1
NHSL1
NHS-like 1
chr10_+_16478942 0.09 ENST00000535784.2
ENST00000423462.2
ENST00000378000.1
PTER
phosphotriesterase related
chr12_+_9142131 0.09 ENST00000356986.3
ENST00000266551.4
KLRG1
killer cell lectin-like receptor subfamily G, member 1
chr10_+_6625605 0.09 ENST00000414894.1
ENST00000449648.1
PRKCQ-AS1
PRKCQ antisense RNA 1
chr1_+_174670143 0.09 ENST00000367687.1
ENST00000347255.2
RABGAP1L
RAB GTPase activating protein 1-like
chr3_+_187957646 0.09 ENST00000457242.1
LPP
LIM domain containing preferred translocation partner in lipoma
chr6_-_52109335 0.09 ENST00000336123.4
IL17F
interleukin 17F
chr3_+_32737027 0.09 ENST00000454516.2
CNOT10
CCR4-NOT transcription complex, subunit 10
chr12_-_133613794 0.09 ENST00000443154.3
RP11-386I8.6
RP11-386I8.6
chr7_-_130597935 0.09 ENST00000447307.1
ENST00000418546.1
MIR29B1
microRNA 29a
chr12_-_8693539 0.09 ENST00000299663.3
CLEC4E
C-type lectin domain family 4, member E
chr1_+_158979680 0.09 ENST00000368131.4
ENST00000340979.6
IFI16
interferon, gamma-inducible protein 16
chr2_+_90198535 0.09 ENST00000390276.2
IGKV1D-12
immunoglobulin kappa variable 1D-12
chr14_+_73525229 0.09 ENST00000527432.1
ENST00000531500.1
ENST00000525321.1
ENST00000526754.1
RBM25
RNA binding motif protein 25
chr9_-_102861267 0.09 ENST00000262455.6
ERP44
endoplasmic reticulum protein 44
chr12_+_97300995 0.09 ENST00000266742.4
ENST00000429527.2
ENST00000554226.1
ENST00000557478.1
ENST00000557092.1
ENST00000411739.2
ENST00000553609.1
NEDD1
neural precursor cell expressed, developmentally down-regulated 1
chr2_-_145277640 0.08 ENST00000539609.3
ZEB2
zinc finger E-box binding homeobox 2
chr9_-_21305312 0.08 ENST00000259555.4
IFNA5
interferon, alpha 5
chr1_-_149459549 0.08 ENST00000369175.3
FAM72C
family with sequence similarity 72, member C
chr2_-_128785688 0.08 ENST00000259234.6
SAP130
Sin3A-associated protein, 130kDa
chr15_-_77712429 0.08 ENST00000564328.1
ENST00000558305.1
PEAK1
pseudopodium-enriched atypical kinase 1
chr3_+_134032331 0.08 ENST00000482019.1
RP11-200A1.1
RP11-200A1.1
chr11_-_104769141 0.08 ENST00000508062.1
ENST00000422698.2
CASP12
caspase 12 (gene/pseudogene)
chr20_+_58533471 0.08 ENST00000244047.5
ENST00000348616.4
CDH26
cadherin 26
chr20_+_6748311 0.08 ENST00000378827.4
BMP2
bone morphogenetic protein 2
chrX_-_119693745 0.08 ENST00000371323.2
CUL4B
cullin 4B
chr13_-_33002279 0.08 ENST00000380130.2
N4BP2L1
NEDD4 binding protein 2-like 1
chr7_+_143318020 0.08 ENST00000444908.2
ENST00000518791.1
ENST00000411497.2
FAM115C
family with sequence similarity 115, member C
chr9_-_32526299 0.08 ENST00000379882.1
ENST00000379883.2
DDX58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chrX_-_71525742 0.08 ENST00000450875.1
ENST00000417400.1
ENST00000431381.1
ENST00000445983.1
CITED1
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
chr1_-_198906528 0.08 ENST00000432296.1
MIR181A1HG
MIR181A1 host gene (non-protein coding)
chr2_-_231090344 0.08 ENST00000540870.1
ENST00000416610.1
SP110
SP110 nuclear body protein
chr19_-_58485895 0.08 ENST00000314391.3
C19orf18
chromosome 19 open reading frame 18
chr12_+_32654965 0.08 ENST00000472289.1
FGD4
FYVE, RhoGEF and PH domain containing 4
chr14_-_67981870 0.08 ENST00000555994.1
TMEM229B
transmembrane protein 229B
chr1_+_104104379 0.08 ENST00000435302.1
AMY2B
amylase, alpha 2B (pancreatic)
chr10_-_18944123 0.08 ENST00000606425.1
RP11-139J15.7
Uncharacterized protein
chr14_-_102552659 0.08 ENST00000441629.2
HSP90AA1
heat shock protein 90kDa alpha (cytosolic), class A member 1
chr12_+_94542459 0.08 ENST00000258526.4
PLXNC1
plexin C1
chr14_+_73525144 0.08 ENST00000261973.7
ENST00000540173.1
RBM25
RNA binding motif protein 25
chr9_+_70971815 0.08 ENST00000396392.1
ENST00000396396.1
PGM5
phosphoglucomutase 5
chr18_-_21977748 0.08 ENST00000399441.4
ENST00000319481.3
OSBPL1A
oxysterol binding protein-like 1A
chr14_-_35183755 0.08 ENST00000555765.1
CFL2
cofilin 2 (muscle)
chr1_+_59486129 0.08 ENST00000438195.1
ENST00000424308.1
RP4-794H19.4
RP4-794H19.4
chrX_+_146993534 0.08 ENST00000334557.6
ENST00000439526.2
ENST00000370475.4
FMR1
fragile X mental retardation 1
chr17_-_62499334 0.08 ENST00000579996.1
DDX5
DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr5_+_140734570 0.08 ENST00000571252.1
PCDHGA4
protocadherin gamma subfamily A, 4
chr4_-_111120334 0.08 ENST00000503885.1
ELOVL6
ELOVL fatty acid elongase 6
chr15_-_89764929 0.08 ENST00000268125.5
RLBP1
retinaldehyde binding protein 1
chr12_-_50616122 0.08 ENST00000552823.1
ENST00000552909.1
LIMA1
LIM domain and actin binding 1
chr12_+_113416340 0.08 ENST00000552756.1
OAS2
2'-5'-oligoadenylate synthetase 2, 69/71kDa
chr4_-_76944621 0.08 ENST00000306602.1
CXCL10
chemokine (C-X-C motif) ligand 10
chr11_-_104905840 0.08 ENST00000526568.1
ENST00000393136.4
ENST00000531166.1
ENST00000534497.1
ENST00000527979.1
ENST00000446369.1
ENST00000353247.5
ENST00000528974.1
ENST00000533400.1
ENST00000525825.1
ENST00000436863.3
CASP1
caspase 1, apoptosis-related cysteine peptidase
chr1_-_193155729 0.08 ENST00000367434.4
B3GALT2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr12_+_80838126 0.08 ENST00000266688.5
PTPRQ
protein tyrosine phosphatase, receptor type, Q
chr9_+_21440440 0.08 ENST00000276927.1
IFNA1
interferon, alpha 1
chr15_+_80364901 0.08 ENST00000560228.1
ENST00000559835.1
ENST00000559775.1
ENST00000558688.1
ENST00000560392.1
ENST00000560976.1
ENST00000558272.1
ENST00000558390.1
ZFAND6
zinc finger, AN1-type domain 6
chr5_+_82373379 0.08 ENST00000396027.4
ENST00000511817.1
XRCC4
X-ray repair complementing defective repair in Chinese hamster cells 4
chr7_+_106685079 0.08 ENST00000265717.4
PRKAR2B
protein kinase, cAMP-dependent, regulatory, type II, beta
chr8_+_109455845 0.08 ENST00000220853.3
EMC2
ER membrane protein complex subunit 2
chr4_+_75174204 0.08 ENST00000332112.4
ENST00000514968.1
ENST00000503098.1
ENST00000502358.1
ENST00000509145.1
ENST00000505212.1
EPGN
epithelial mitogen
chr1_+_2066252 0.08 ENST00000466352.1
PRKCZ
protein kinase C, zeta
chr7_+_23221438 0.08 ENST00000258742.5
NUPL2
nucleoporin like 2
chr2_+_42104692 0.08 ENST00000398796.2
ENST00000442214.1
AC104654.1
AC104654.1
chr3_-_179169181 0.08 ENST00000497513.1
GNB4
guanine nucleotide binding protein (G protein), beta polypeptide 4

Network of associatons between targets according to the STRING database.

First level regulatory network of IRF7

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.1 0.4 GO:0060629 meiotic DNA double-strand break formation(GO:0042138) regulation of homologous chromosome segregation(GO:0060629)
0.1 0.3 GO:0032714 negative regulation of interleukin-5 production(GO:0032714)
0.1 0.4 GO:0034344 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.1 0.3 GO:0006147 guanine catabolic process(GO:0006147)
0.1 0.2 GO:0045062 extrathymic T cell selection(GO:0045062)
0.1 0.3 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.1 1.0 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.1 0.2 GO:1901254 modulation by host of viral RNA genome replication(GO:0044830) positive regulation of intracellular transport of viral material(GO:1901254)
0.1 0.5 GO:0044565 dendritic cell proliferation(GO:0044565)
0.1 0.2 GO:0060437 lung growth(GO:0060437)
0.1 0.2 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.0 0.0 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.0 0.2 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.0 0.1 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.0 0.3 GO:2000510 positive regulation of dendritic cell chemotaxis(GO:2000510)
0.0 0.0 GO:0046832 negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.0 0.5 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.1 GO:0031443 fast-twitch skeletal muscle fiber contraction(GO:0031443)
0.0 0.2 GO:0030885 regulation of myeloid dendritic cell activation(GO:0030885)
0.0 0.1 GO:0071283 cellular response to iron(III) ion(GO:0071283)
0.0 0.2 GO:0030421 defecation(GO:0030421)
0.0 0.3 GO:0071104 response to interleukin-9(GO:0071104)
0.0 0.0 GO:1901252 negative regulation of dendritic cell cytokine production(GO:0002731) regulation of intracellular transport of viral material(GO:1901252)
0.0 0.6 GO:0002385 mucosal immune response(GO:0002385)
0.0 0.1 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.0 0.1 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.1 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0 0.4 GO:1904896 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.0 0.2 GO:0008218 bioluminescence(GO:0008218)
0.0 0.1 GO:0021569 rhombomere 3 development(GO:0021569)
0.0 0.1 GO:0006154 adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103)
0.0 0.1 GO:0006533 aspartate catabolic process(GO:0006533)
0.0 0.1 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.0 0.1 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0 0.1 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.0 0.1 GO:0061209 BMP signaling pathway involved in heart induction(GO:0003130) endodermal-mesodermal cell signaling(GO:0003133) endodermal-mesodermal cell signaling involved in heart induction(GO:0003134) cell proliferation involved in mesonephros development(GO:0061209) mesenchymal cell proliferation involved in ureteric bud development(GO:0072138)
0.0 0.1 GO:0072308 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.0 0.2 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.1 GO:0045196 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0 0.2 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.0 0.1 GO:0006597 spermine biosynthetic process(GO:0006597)
0.0 0.1 GO:0070631 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.0 0.1 GO:0061056 sclerotome development(GO:0061056)
0.0 0.1 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.0 0.2 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.0 0.1 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 0.1 GO:0002881 negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
0.0 0.2 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.1 GO:0038185 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.0 0.1 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.0 0.1 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.1 GO:0043335 protein unfolding(GO:0043335)
0.0 0.1 GO:1903056 mammillary body development(GO:0021767) mammillary axonal complex development(GO:0061373) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.0 0.0 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.0 0.1 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.0 0.0 GO:0030070 insulin processing(GO:0030070)
0.0 0.0 GO:0021882 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) regulation of amacrine cell differentiation(GO:1902869) positive regulation of amacrine cell differentiation(GO:1902871)
0.0 0.0 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.0 0.2 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 0.1 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.1 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.0 0.1 GO:1905123 regulation of endosome organization(GO:1904978) regulation of glucosylceramidase activity(GO:1905123)
0.0 0.1 GO:0045423 regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423)
0.0 0.1 GO:1902728 positive regulation of skeletal muscle cell proliferation(GO:0014858) mineralocorticoid receptor signaling pathway(GO:0031959) positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.0 0.1 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.0 0.0 GO:1902725 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723) negative regulation of satellite cell differentiation(GO:1902725)
0.0 0.1 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.0 0.0 GO:0042253 granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0042253)
0.0 0.1 GO:0071492 cellular response to UV-A(GO:0071492)
0.0 0.0 GO:0086092 regulation of the force of heart contraction by cardiac conduction(GO:0086092)
0.0 0.1 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.2 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.1 GO:0052148 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.0 0.1 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.1 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.0 0.1 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.1 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.0 0.1 GO:0009956 radial pattern formation(GO:0009956)
0.0 0.1 GO:0018377 protein myristoylation(GO:0018377)
0.0 0.1 GO:0015705 iodide transport(GO:0015705)
0.0 0.3 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.2 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.1 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0 0.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.0 GO:0018197 peptidyl-aspartic acid modification(GO:0018197) peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.0 GO:1901420 negative regulation of vitamin D receptor signaling pathway(GO:0070563) negative regulation of response to alcohol(GO:1901420)
0.0 0.1 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.1 GO:0043686 co-translational protein modification(GO:0043686)
0.0 0.0 GO:0097069 cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387)
0.0 0.1 GO:0051121 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.1 GO:0071494 cellular response to UV-C(GO:0071494)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.1 0.2 GO:1902737 dendritic filopodium(GO:1902737)
0.1 0.3 GO:0031906 late endosome lumen(GO:0031906)
0.1 0.2 GO:0031213 RSF complex(GO:0031213)
0.1 0.2 GO:0018444 translation release factor complex(GO:0018444)
0.0 0.2 GO:0097179 protease inhibitor complex(GO:0097179)
0.0 0.4 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.2 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0 0.1 GO:0031905 early endosome lumen(GO:0031905)
0.0 0.2 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.1 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.0 0.2 GO:0097422 tubular endosome(GO:0097422)
0.0 0.1 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
0.0 0.1 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 0.0 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.0 0.1 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.0 GO:0072534 perineuronal net(GO:0072534)
0.0 0.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.1 GO:0032010 phagolysosome(GO:0032010)
0.0 0.1 GO:0035370 UBC13-UEV1A complex(GO:0035370)
0.0 0.0 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0008892 guanine deaminase activity(GO:0008892)
0.1 0.5 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.3 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.1 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.1 GO:0070336 flap-structured DNA binding(GO:0070336)
0.0 0.1 GO:0030626 U12 snRNA binding(GO:0030626)
0.0 0.2 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.2 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.2 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.1 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.0 0.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.1 GO:0016768 spermine synthase activity(GO:0016768)
0.0 0.1 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.1 GO:0009041 uridylate kinase activity(GO:0009041)
0.0 0.1 GO:0070052 collagen V binding(GO:0070052)
0.0 0.1 GO:0004556 alpha-amylase activity(GO:0004556)
0.0 0.2 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.2 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.3 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.2 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.1 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.0 0.1 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0 0.1 GO:0016495 C-X3-C chemokine receptor activity(GO:0016495)
0.0 0.1 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.1 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.0 0.1 GO:0051120 hepoxilin A3 synthase activity(GO:0051120)
0.0 0.1 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.0 0.0 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.1 GO:0004473 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.0 0.1 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.0 0.0 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.1 GO:0098808 mRNA cap binding(GO:0098808)
0.0 0.1 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0 0.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.1 GO:0043426 MRF binding(GO:0043426)
0.0 0.1 GO:0022897 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0 0.1 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0089720 caspase binding(GO:0089720)
0.0 0.0 GO:0005174 CD40 receptor binding(GO:0005174)
0.0 0.1 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 0.1 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.0 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.0 0.1 GO:0070573 metallodipeptidase activity(GO:0070573)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.2 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.4 PID IL27 PATHWAY IL27-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.7 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.2 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 0.5 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 1.0 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling