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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for IRF9

Z-value: 0.96

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Transcription factors associated with IRF9

Gene Symbol Gene ID Gene Info
IRF9
ENSG00000213928.4 interferon regulatory factor 9

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
IRF9hg19_v2_chr14_+_24630465_24630531-0.831.7e-01Click!

Activity profile of IRF9 motif

Sorted Z-values of IRF9 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_+_6659153 0.65 ENST00000441631.1
ENST00000438512.1
ENST00000346752.4
ENST00000361842.3
XAF1
XIAP associated factor 1
chr12_-_121477039 0.60 ENST00000257570.5
OASL
2'-5'-oligoadenylate synthetase-like
chr12_-_121476959 0.53 ENST00000339275.5
OASL
2'-5'-oligoadenylate synthetase-like
chr12_-_121476750 0.42 ENST00000543677.1
OASL
2'-5'-oligoadenylate synthetase-like
chr16_+_53412368 0.37 ENST00000565189.1
RP11-44F14.2
RP11-44F14.2
chr2_-_163175133 0.36 ENST00000421365.2
ENST00000263642.2
IFIH1
interferon induced with helicase C domain 1
chr19_+_16254488 0.36 ENST00000588246.1
ENST00000593031.1
HSH2D
hematopoietic SH2 domain containing
chr10_+_91061712 0.27 ENST00000371826.3
IFIT2
interferon-induced protein with tetratricopeptide repeats 2
chr10_+_91092241 0.27 ENST00000371811.4
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr17_-_40264692 0.27 ENST00000591220.1
ENST00000251642.3
DHX58
DEXH (Asp-Glu-X-His) box polypeptide 58
chr4_-_76944621 0.26 ENST00000306602.1
CXCL10
chemokine (C-X-C motif) ligand 10
chr4_-_147442817 0.26 ENST00000507030.1
SLC10A7
solute carrier family 10, member 7
chr9_+_33264861 0.24 ENST00000223500.8
CHMP5
charged multivesicular body protein 5
chr9_-_32526184 0.24 ENST00000545044.1
ENST00000379868.1
DDX58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr3_+_159706537 0.24 ENST00000305579.2
ENST00000480787.1
ENST00000466512.1
IL12A
interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
chr9_+_33265011 0.23 ENST00000419016.2
CHMP5
charged multivesicular body protein 5
chr4_+_186990298 0.23 ENST00000296795.3
ENST00000513189.1
TLR3
toll-like receptor 3
chr16_-_74734672 0.22 ENST00000306247.7
ENST00000575686.1
MLKL
mixed lineage kinase domain-like
chr1_-_154167124 0.22 ENST00000515609.1
TPM3
tropomyosin 3
chr9_+_74764278 0.21 ENST00000238018.4
ENST00000376989.3
GDA
guanine deaminase
chr2_-_7005785 0.21 ENST00000256722.5
ENST00000404168.1
ENST00000458098.1
CMPK2
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr12_+_113344755 0.20 ENST00000550883.1
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr17_+_46908350 0.20 ENST00000258947.3
ENST00000509507.1
ENST00000448105.2
ENST00000570513.1
ENST00000509415.1
ENST00000513119.1
ENST00000416445.2
ENST00000508679.1
ENST00000505071.1
CALCOCO2
calcium binding and coiled-coil domain 2
chr4_-_75719896 0.20 ENST00000395743.3
BTC
betacellulin
chr2_-_152118276 0.20 ENST00000409092.1
RBM43
RNA binding motif protein 43
chr4_-_147442982 0.19 ENST00000511374.1
ENST00000264986.3
SLC10A7
solute carrier family 10, member 7
chr1_+_79115503 0.19 ENST00000370747.4
ENST00000438486.1
ENST00000545124.1
IFI44
interferon-induced protein 44
chr14_+_94577074 0.18 ENST00000444961.1
ENST00000448882.1
ENST00000557098.1
ENST00000554800.1
ENST00000556544.1
ENST00000298902.5
ENST00000555819.1
ENST00000557634.1
ENST00000555744.1
IFI27
interferon, alpha-inducible protein 27
chr3_-_179169181 0.18 ENST00000497513.1
GNB4
guanine nucleotide binding protein (G protein), beta polypeptide 4
chr9_+_70971815 0.16 ENST00000396392.1
ENST00000396396.1
PGM5
phosphoglucomutase 5
chr10_+_91174486 0.16 ENST00000416601.1
IFIT5
interferon-induced protein with tetratricopeptide repeats 5
chr2_+_33701684 0.15 ENST00000442390.1
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr2_-_55920952 0.15 ENST00000447944.2
PNPT1
polyribonucleotide nucleotidyltransferase 1
chr2_-_37384175 0.14 ENST00000411537.2
ENST00000233057.4
ENST00000395127.2
ENST00000390013.3
EIF2AK2
eukaryotic translation initiation factor 2-alpha kinase 2
chr3_-_146262365 0.14 ENST00000448787.2
PLSCR1
phospholipid scramblase 1
chr4_+_89378261 0.14 ENST00000264350.3
HERC5
HECT and RLD domain containing E3 ubiquitin protein ligase 5
chr17_-_74489215 0.14 ENST00000585701.1
ENST00000591192.1
ENST00000589526.1
RHBDF2
rhomboid 5 homolog 2 (Drosophila)
chr3_-_28389922 0.14 ENST00000415852.1
AZI2
5-azacytidine induced 2
chr3_-_146262352 0.14 ENST00000462666.1
PLSCR1
phospholipid scramblase 1
chr3_-_28390120 0.14 ENST00000334100.6
AZI2
5-azacytidine induced 2
chr12_+_113344582 0.14 ENST00000202917.5
ENST00000445409.2
ENST00000452357.2
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr2_+_33701707 0.14 ENST00000425210.1
ENST00000444784.1
ENST00000423159.1
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr19_-_17516449 0.13 ENST00000252593.6
BST2
bone marrow stromal cell antigen 2
chr7_-_105332084 0.13 ENST00000472195.1
ATXN7L1
ataxin 7-like 1
chr3_-_122283424 0.13 ENST00000477522.2
ENST00000360356.2
PARP9
poly (ADP-ribose) polymerase family, member 9
chr3_-_28390581 0.12 ENST00000479665.1
AZI2
5-azacytidine induced 2
chr17_+_6659354 0.12 ENST00000574907.1
XAF1
XIAP associated factor 1
chr15_+_45003675 0.12 ENST00000558401.1
ENST00000559916.1
ENST00000544417.1
B2M
beta-2-microglobulin
chr13_+_50070491 0.12 ENST00000496612.1
ENST00000357596.3
ENST00000485919.1
ENST00000442195.1
PHF11
PHD finger protein 11
chr3_-_141747439 0.12 ENST00000467667.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr4_-_100140331 0.11 ENST00000407820.2
ENST00000394897.1
ENST00000508558.1
ENST00000394899.2
ADH6
alcohol dehydrogenase 6 (class V)
chr3_-_142166846 0.11 ENST00000463916.1
ENST00000544157.1
XRN1
5'-3' exoribonuclease 1
chr3_-_122283079 0.11 ENST00000471785.1
ENST00000466126.1
PARP9
poly (ADP-ribose) polymerase family, member 9
chr14_-_67981870 0.11 ENST00000555994.1
TMEM229B
transmembrane protein 229B
chr6_-_8102714 0.11 ENST00000502429.1
ENST00000429723.2
ENST00000507463.1
ENST00000379715.5
EEF1E1
eukaryotic translation elongation factor 1 epsilon 1
chr9_+_74764340 0.11 ENST00000376986.1
ENST00000358399.3
GDA
guanine deaminase
chr10_+_91174314 0.11 ENST00000371795.4
IFIT5
interferon-induced protein with tetratricopeptide repeats 5
chr9_-_32526299 0.11 ENST00000379882.1
ENST00000379883.2
DDX58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr4_+_37892682 0.11 ENST00000508802.1
ENST00000261439.4
ENST00000402522.1
TBC1D1
TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
chr3_-_142166796 0.10 ENST00000392981.2
XRN1
5'-3' exoribonuclease 1
chr17_+_41363854 0.10 ENST00000588693.1
ENST00000588659.1
ENST00000541594.1
ENST00000536052.1
ENST00000331615.3
TMEM106A
transmembrane protein 106A
chr4_-_169401628 0.10 ENST00000514748.1
ENST00000512371.1
ENST00000260184.7
ENST00000505890.1
ENST00000511577.1
DDX60L
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like
chr5_-_142783694 0.10 ENST00000394466.2
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr3_-_28390415 0.10 ENST00000414162.1
ENST00000420543.2
AZI2
5-azacytidine induced 2
chr1_-_150738261 0.09 ENST00000448301.2
ENST00000368985.3
CTSS
cathepsin S
chr6_-_105584560 0.09 ENST00000336775.5
BVES
blood vessel epicardial substance
chr3_+_122399444 0.09 ENST00000474629.2
PARP14
poly (ADP-ribose) polymerase family, member 14
chr4_-_77134742 0.09 ENST00000452464.2
SCARB2
scavenger receptor class B, member 2
chr3_-_28390298 0.09 ENST00000457172.1
AZI2
5-azacytidine induced 2
chr4_+_146402997 0.09 ENST00000512019.1
SMAD1
SMAD family member 1
chr5_-_95297534 0.09 ENST00000513343.1
ENST00000431061.2
ELL2
elongation factor, RNA polymerase II, 2
chr2_-_152146385 0.08 ENST00000414946.1
ENST00000243346.5
NMI
N-myc (and STAT) interactor
chr3_-_27764190 0.08 ENST00000537516.1
EOMES
eomesodermin
chr3_-_141747459 0.08 ENST00000477292.1
ENST00000478006.1
ENST00000495310.1
ENST00000486111.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr11_-_4414880 0.08 ENST00000254436.7
ENST00000543625.1
TRIM21
tripartite motif containing 21
chr5_-_137911049 0.08 ENST00000297185.3
HSPA9
heat shock 70kDa protein 9 (mortalin)
chr4_+_146402925 0.08 ENST00000302085.4
SMAD1
SMAD family member 1
chr1_+_66820058 0.08 ENST00000480109.2
PDE4B
phosphodiesterase 4B, cAMP-specific
chr3_-_121379739 0.07 ENST00000428394.2
ENST00000314583.3
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr11_-_60720002 0.07 ENST00000538739.1
SLC15A3
solute carrier family 15 (oligopeptide transporter), member 3
chr1_+_162602244 0.07 ENST00000367922.3
ENST00000367921.3
DDR2
discoidin domain receptor tyrosine kinase 2
chr9_+_102668915 0.07 ENST00000259400.6
ENST00000531035.1
ENST00000525640.1
ENST00000534052.1
ENST00000526607.1
STX17
syntaxin 17
chr12_+_113344811 0.07 ENST00000551241.1
ENST00000553185.1
ENST00000550689.1
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr4_-_169239921 0.07 ENST00000514995.1
ENST00000393743.3
DDX60
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
chr2_-_106810783 0.07 ENST00000283148.7
UXS1
UDP-glucuronate decarboxylase 1
chr5_-_142784003 0.06 ENST00000416954.2
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr1_+_59486129 0.06 ENST00000438195.1
ENST00000424308.1
RP4-794H19.4
RP4-794H19.4
chr21_+_42798124 0.06 ENST00000417963.1
MX1
myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)
chr21_+_42798094 0.06 ENST00000398598.3
ENST00000455164.2
ENST00000424365.1
MX1
myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)
chrX_-_39956656 0.06 ENST00000397354.3
ENST00000378444.4
BCOR
BCL6 corepressor
chr2_-_106810742 0.06 ENST00000409501.3
ENST00000428048.2
ENST00000441952.1
ENST00000457835.1
ENST00000540130.1
UXS1
UDP-glucuronate decarboxylase 1
chr19_+_10222189 0.05 ENST00000321826.4
P2RY11
purinergic receptor P2Y, G-protein coupled, 11
chr13_+_50070077 0.05 ENST00000378319.3
ENST00000426879.1
PHF11
PHD finger protein 11
chr2_+_7073174 0.05 ENST00000416587.1
RNF144A
ring finger protein 144A
chr2_+_205410516 0.05 ENST00000406610.2
ENST00000462231.1
PARD3B
par-3 family cell polarity regulator beta
chr11_-_57335280 0.05 ENST00000287156.4
UBE2L6
ubiquitin-conjugating enzyme E2L 6
chr5_-_95297678 0.05 ENST00000237853.4
ELL2
elongation factor, RNA polymerase II, 2
chr6_-_82462425 0.05 ENST00000369754.3
ENST00000320172.6
ENST00000369756.3
FAM46A
family with sequence similarity 46, member A
chr1_+_158979792 0.05 ENST00000359709.3
ENST00000430894.2
IFI16
interferon, gamma-inducible protein 16
chr16_-_15736881 0.05 ENST00000540441.2
KIAA0430
KIAA0430
chrX_-_48858667 0.05 ENST00000376423.4
ENST00000376441.1
GRIPAP1
GRIP1 associated protein 1
chr14_-_67981916 0.05 ENST00000357461.2
TMEM229B
transmembrane protein 229B
chr10_-_25241499 0.04 ENST00000376378.1
ENST00000376376.3
ENST00000320152.6
PRTFDC1
phosphoribosyl transferase domain containing 1
chr11_-_615570 0.04 ENST00000525445.1
ENST00000348655.6
ENST00000397566.1
IRF7
interferon regulatory factor 7
chrX_-_48858630 0.04 ENST00000376425.3
ENST00000376444.3
GRIPAP1
GRIP1 associated protein 1
chr11_-_57334732 0.04 ENST00000526659.1
ENST00000527022.1
UBE2L6
ubiquitin-conjugating enzyme E2L 6
chr17_-_54991369 0.04 ENST00000537230.1
TRIM25
tripartite motif containing 25
chr11_-_86383157 0.04 ENST00000393324.3
ME3
malic enzyme 3, NADP(+)-dependent, mitochondrial
chr14_+_100531615 0.04 ENST00000392920.3
EVL
Enah/Vasp-like
chr3_-_146262428 0.03 ENST00000486631.1
PLSCR1
phospholipid scramblase 1
chr10_-_91174215 0.03 ENST00000371837.1
LIPA
lipase A, lysosomal acid, cholesterol esterase
chr9_-_33264557 0.03 ENST00000473781.1
ENST00000488499.1
BAG1
BCL2-associated athanogene
chr20_+_11898507 0.03 ENST00000378226.2
BTBD3
BTB (POZ) domain containing 3
chr1_+_158979686 0.03 ENST00000368132.3
ENST00000295809.7
IFI16
interferon, gamma-inducible protein 16
chr5_-_59481406 0.03 ENST00000546160.1
PDE4D
phosphodiesterase 4D, cAMP-specific
chr3_-_146262637 0.03 ENST00000472349.1
ENST00000342435.4
PLSCR1
phospholipid scramblase 1
chr11_+_5646213 0.03 ENST00000429814.2
TRIM34
tripartite motif containing 34
chr3_-_122283100 0.03 ENST00000492382.1
ENST00000462315.1
PARP9
poly (ADP-ribose) polymerase family, member 9
chr18_+_3262954 0.03 ENST00000584539.1
MYL12B
myosin, light chain 12B, regulatory
chr10_+_115439699 0.03 ENST00000369315.1
CASP7
caspase 7, apoptosis-related cysteine peptidase
chr6_-_31324943 0.03 ENST00000412585.2
ENST00000434333.1
HLA-B
major histocompatibility complex, class I, B
chr15_+_91643442 0.02 ENST00000394232.1
SV2B
synaptic vesicle glycoprotein 2B
chr4_-_77135046 0.02 ENST00000264896.2
SCARB2
scavenger receptor class B, member 2
chr17_+_78234625 0.02 ENST00000508628.2
ENST00000582970.1
ENST00000456466.1
ENST00000319921.4
RNF213
ring finger protein 213
chr2_+_205410723 0.02 ENST00000358768.2
ENST00000351153.1
ENST00000349953.3
PARD3B
par-3 family cell polarity regulator beta
chr1_-_234667504 0.02 ENST00000421207.1
ENST00000435574.1
RP5-855F14.1
RP5-855F14.1
chr10_+_115439282 0.02 ENST00000369321.2
ENST00000345633.4
CASP7
caspase 7, apoptosis-related cysteine peptidase
chrX_-_63005405 0.02 ENST00000374878.1
ENST00000437457.2
ARHGEF9
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr6_+_126240442 0.02 ENST00000448104.1
ENST00000438495.1
ENST00000444128.1
NCOA7
nuclear receptor coactivator 7
chr15_+_58702742 0.02 ENST00000356113.6
ENST00000414170.3
LIPC
lipase, hepatic
chr15_+_74287118 0.02 ENST00000563500.1
PML
promyelocytic leukemia
chr3_+_122283064 0.02 ENST00000296161.4
DTX3L
deltex 3-like (Drosophila)
chr3_+_151986709 0.02 ENST00000495875.2
ENST00000493459.1
ENST00000324210.5
ENST00000459747.1
MBNL1
muscleblind-like splicing regulator 1
chr10_+_115439630 0.02 ENST00000369318.3
CASP7
caspase 7, apoptosis-related cysteine peptidase
chr21_+_42797958 0.02 ENST00000419044.1
MX1
myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)
chr10_-_95242044 0.01 ENST00000371501.4
ENST00000371502.4
ENST00000371489.1
MYOF
myoferlin
chr5_-_142783175 0.01 ENST00000231509.3
ENST00000394464.2
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr17_+_6658878 0.01 ENST00000574394.1
XAF1
XIAP associated factor 1
chr20_-_56195449 0.01 ENST00000541799.1
ZBP1
Z-DNA binding protein 1
chr1_+_236687881 0.01 ENST00000526634.1
LGALS8
lectin, galactoside-binding, soluble, 8
chr10_-_95241951 0.01 ENST00000358334.5
ENST00000359263.4
ENST00000371488.3
MYOF
myoferlin
chr18_-_67624412 0.00 ENST00000580335.1
CD226
CD226 molecule
chr3_+_122283175 0.00 ENST00000383661.3
DTX3L
deltex 3-like (Drosophila)
chr19_+_10196981 0.00 ENST00000591813.1
C19orf66
chromosome 19 open reading frame 66

Network of associatons between targets according to the STRING database.

First level regulatory network of IRF9

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0034343 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.1 0.3 GO:0006147 guanine catabolic process(GO:0006147)
0.1 0.6 GO:0044565 dendritic cell proliferation(GO:0044565)
0.1 0.3 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.1 0.2 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0 0.1 GO:2000627 rRNA import into mitochondrion(GO:0035928) regulation of miRNA catabolic process(GO:2000625) positive regulation of miRNA catabolic process(GO:2000627)
0.0 0.1 GO:0002731 negative regulation of dendritic cell cytokine production(GO:0002731)
0.0 0.2 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.0 0.1 GO:0033319 UDP-D-xylose metabolic process(GO:0033319) UDP-D-xylose biosynthetic process(GO:0033320)
0.0 0.1 GO:1904432 positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440)
0.0 0.5 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 0.4 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902) negative regulation of membrane depolarization(GO:1904180)
0.0 0.3 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659) regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
0.0 0.2 GO:2000510 positive regulation of dendritic cell chemotaxis(GO:2000510)
0.0 0.1 GO:1905123 regulation of endosome organization(GO:1904978) regulation of glucosylceramidase activity(GO:1905123)
0.0 0.5 GO:1904903 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.0 0.3 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.3 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.1 GO:0060931 sinoatrial node cell development(GO:0060931)
0.0 0.8 GO:0035456 response to interferon-beta(GO:0035456)
0.0 0.2 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.1 GO:0045349 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.0 1.7 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.1 GO:0090086 negative regulation of protein deubiquitination(GO:0090086)
0.0 0.1 GO:0050709 negative regulation of protein secretion(GO:0050709)
0.0 0.0 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.0 0.2 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.1 GO:0016240 autophagosome docking(GO:0016240)
0.0 0.1 GO:0060809 mesodermal to mesenchymal transition involved in gastrulation(GO:0060809)
0.0 0.2 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.1 GO:1905244 regulation of modification of synaptic structure(GO:1905244)
0.0 0.1 GO:2000774 positive regulation of cellular senescence(GO:2000774)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0031906 late endosome lumen(GO:0031906)
0.0 0.1 GO:0031905 early endosome lumen(GO:0031905)
0.0 0.1 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.0 0.1 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.1 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.2 GO:0005862 muscle thin filament tropomyosin(GO:0005862)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.3 GO:0008892 guanine deaminase activity(GO:0008892)
0.1 0.3 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 0.2 GO:0009041 uridylate kinase activity(GO:0009041)
0.0 0.1 GO:0048040 UDP-glucuronate decarboxylase activity(GO:0048040)
0.0 0.2 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.1 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 0.2 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.2 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.2 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.1 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.3 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.1 GO:0022897 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0 1.3 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.1 GO:0038051 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.7 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 2.4 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.2 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.5 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)