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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for IRX3

Z-value: 1.72

Motif logo

Transcription factors associated with IRX3

Gene Symbol Gene ID Gene Info
ENSG00000177508.11 iroquois homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
IRX3hg19_v2_chr16_-_54320675_54320715-0.584.2e-01Click!

Activity profile of IRX3 motif

Sorted Z-values of IRX3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chrX_+_150866779 0.95 ENST00000370353.3
proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane)
chr12_-_21757774 0.92 ENST00000261195.2
glycogen synthase 2 (liver)
chr3_-_185641681 0.80 ENST00000259043.7
transformer 2 beta homolog (Drosophila)
chr17_-_15469590 0.73 ENST00000312127.2
CMT duplicated region transcript 1; Uncharacterized protein
chr16_-_66864806 0.68 ENST00000566336.1
ENST00000394074.2
ENST00000563185.2
ENST00000359087.4
ENST00000379463.2
ENST00000565535.1
ENST00000290810.3
NEDD8 activating enzyme E1 subunit 1
chr5_-_156390230 0.67 ENST00000407087.3
ENST00000274532.2
T-cell immunoglobulin and mucin domain containing 4
chr14_+_39944025 0.66 ENST00000554328.1
ENST00000556620.1
ENST00000557197.1
RP11-111A21.1
chr22_+_22556057 0.65 ENST00000390286.2
immunoglobulin lambda variable 11-55 (non-functional)
chr5_+_81601166 0.64 ENST00000439350.1
ATPase, H+ transporting, lysosomal accessory protein 1-like
chr7_+_40174565 0.62 ENST00000309930.5
ENST00000401647.2
ENST00000335693.4
ENST00000413931.1
ENST00000416370.1
ENST00000540834.1
succinylCoA:glutarate-CoA transferase
chr19_-_38743878 0.61 ENST00000587515.1
protein phosphatase 1, regulatory (inhibitor) subunit 14A
chr3_-_93747425 0.60 ENST00000315099.2
syntaxin 19
chr5_+_169011033 0.59 ENST00000513795.1
spindle apparatus coiled-coil protein 1
chr12_+_11187087 0.58 ENST00000601123.1
Uncharacterized protein
chr5_-_156362666 0.57 ENST00000406964.1
T-cell immunoglobulin and mucin domain containing 4
chr13_-_44735393 0.55 ENST00000400419.1
small integral membrane protein 2
chr5_+_136070614 0.54 ENST00000502421.1
CTB-1I21.1
chr3_-_48659193 0.53 ENST00000330862.3
transmembrane protein 89
chr7_-_151330218 0.53 ENST00000476632.1
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr19_+_54960790 0.50 ENST00000443957.1
leukocyte receptor cluster (LRC) member 8
chr3_+_171561127 0.50 ENST00000334567.5
ENST00000450693.1
transmembrane protein 212
chr11_-_46113756 0.50 ENST00000531959.1
PHD finger protein 21A
chr12_+_2912363 0.49 ENST00000544366.1
FK506 binding protein 4, 59kDa
chr17_-_34207295 0.49 ENST00000463941.1
ENST00000293272.3
chemokine (C-C motif) ligand 5
chr8_+_52730143 0.47 ENST00000415643.1
Uncharacterized protein
chr9_+_135937365 0.47 ENST00000372080.4
ENST00000351304.7
carboxyl ester lipase
chr6_+_31691121 0.46 ENST00000480039.1
ENST00000375810.4
ENST00000375805.2
ENST00000375809.3
ENST00000375804.2
ENST00000375814.3
ENST00000375806.2
chromosome 6 open reading frame 25
chr4_-_104119528 0.45 ENST00000380026.3
ENST00000503705.1
ENST00000265148.3
centromere protein E, 312kDa
chr11_+_35201826 0.45 ENST00000531873.1
CD44 molecule (Indian blood group)
chr8_-_56986768 0.45 ENST00000523936.1
ribosomal protein S20
chr14_-_92247032 0.45 ENST00000556661.1
ENST00000553676.1
ENST00000554560.1
catsper channel auxiliary subunit beta
chr10_-_18944123 0.44 ENST00000606425.1
Uncharacterized protein
chr10_-_5227096 0.44 ENST00000488756.1
ENST00000334314.3
aldo-keto reductase family 1, member C-like 1
chr5_+_56205081 0.44 ENST00000285947.2
ENST00000541720.1
SET domain containing 9
chr4_-_39367949 0.44 ENST00000503784.1
ENST00000349703.2
ENST00000381897.1
replication factor C (activator 1) 1, 145kDa
chr20_+_10199566 0.43 ENST00000430336.1
synaptosomal-associated protein, 25kDa
chrX_+_108779004 0.43 ENST00000218004.1
nuclear transport factor 2-like export factor 2
chr4_-_104119488 0.43 ENST00000514974.1
centromere protein E, 312kDa
chr11_+_33037652 0.43 ENST00000311388.3
DEP domain containing 7
chr1_-_197744763 0.42 ENST00000422998.1
DENN/MADD domain containing 1B
chr15_+_66585555 0.42 ENST00000319194.5
ENST00000525134.2
ENST00000441424.2
DIS3 mitotic control homolog (S. cerevisiae)-like
chr12_-_91546926 0.42 ENST00000550758.1
decorin
chr4_+_56212505 0.42 ENST00000505210.1
steroid 5 alpha-reductase 3
chr16_+_81070792 0.42 ENST00000564241.1
ENST00000565237.1
ATM interactor
chr8_-_56987061 0.42 ENST00000009589.3
ENST00000524349.1
ENST00000519606.1
ENST00000519807.1
ENST00000521262.1
ENST00000520627.1
ribosomal protein S20
chr15_+_72947079 0.42 ENST00000421285.3
golgin A6 family, member B
chr7_+_120591170 0.41 ENST00000431467.1
inhibitor of growth family, member 3
chr15_+_49170083 0.41 ENST00000530028.2
EP300 interacting inhibitor of differentiation 1
chr14_+_89060739 0.41 ENST00000318308.6
zinc finger CCCH-type containing 14
chr1_+_145525015 0.41 ENST00000539363.1
ENST00000538811.1
integrin, alpha 10
chr1_+_154909803 0.40 ENST00000604546.1
RP11-307C12.13
chr11_+_60739249 0.40 ENST00000542157.1
ENST00000433107.2
ENST00000452451.2
ENST00000352009.5
CD6 molecule
chr6_-_138833630 0.40 ENST00000533765.1
NHS-like 1
chr7_-_101212244 0.38 ENST00000451953.1
ENST00000434537.1
ENST00000437900.1
long intergenic non-protein coding RNA 1007
chr17_-_26127525 0.37 ENST00000313735.6
nitric oxide synthase 2, inducible
chr19_+_20959098 0.36 ENST00000360204.5
ENST00000594534.1
zinc finger protein 66
chr10_-_112678904 0.36 ENST00000423273.1
ENST00000436562.1
ENST00000447005.1
ENST00000454061.1
BBSome interacting protein 1
chr4_-_144826682 0.36 ENST00000358615.4
ENST00000437468.2
glycophorin E (MNS blood group)
chr16_-_21442874 0.36 ENST00000534903.1
nuclear pore complex interacting protein family, member B3
chr13_+_37581115 0.36 ENST00000481013.1
exosome component 8
chr9_+_67968793 0.36 ENST00000417488.1
Protein LOC644249
chr16_-_3493528 0.35 ENST00000301744.4
zinc finger protein 597
chr16_-_9030515 0.35 ENST00000535863.1
ENST00000381886.4
ubiquitin specific peptidase 7 (herpes virus-associated)
chr12_-_123728548 0.35 ENST00000545406.1
M-phase phosphoprotein 9
chrX_-_100129320 0.35 ENST00000372966.3
NADPH oxidase 1
chr12_-_13248598 0.35 ENST00000337630.6
ENST00000545699.1
germ cell associated 1
chrX_-_55187531 0.35 ENST00000489298.1
ENST00000477847.2
family with sequence similarity 104, member B
chr11_+_74303612 0.35 ENST00000527458.1
ENST00000532497.1
ENST00000530511.1
polymerase (DNA-directed), delta 3, accessory subunit
chr11_+_810221 0.35 ENST00000530398.1
ribosomal protein, large, P2
chr4_+_74606223 0.35 ENST00000307407.3
ENST00000401931.1
interleukin 8
chr19_+_58193337 0.35 ENST00000601064.1
ENST00000282296.5
ENST00000356715.4
zinc finger protein 551
chr19_+_58193388 0.35 ENST00000596085.1
ENST00000594684.1
zinc finger protein 551
Uncharacterized protein
chr12_-_100486668 0.35 ENST00000550544.1
ENST00000551980.1
ENST00000548045.1
ENST00000545232.2
ENST00000551973.1
UHRF1 binding protein 1-like
chr11_-_134123142 0.34 ENST00000392595.2
ENST00000341541.3
ENST00000352327.5
ENST00000392594.3
thymocyte nuclear protein 1
chr10_+_52094298 0.34 ENST00000595931.1
HCG1745369; PRO3073; Uncharacterized protein
chr4_-_186125077 0.34 ENST00000458385.2
ENST00000514798.1
ENST00000296775.6
KIAA1430
chr1_-_248005254 0.34 ENST00000355784.2
olfactory receptor, family 11, subfamily L, member 1
chr10_+_13628933 0.33 ENST00000417658.1
ENST00000320054.4
pre-mRNA processing factor 18
chr14_+_104177607 0.33 ENST00000429169.1
Uncharacterized protein; cDNA FLJ53535
chr4_-_84035905 0.33 ENST00000311507.4
placenta-specific 8
chr4_+_76871883 0.33 ENST00000599764.1
Uncharacterized protein
chr8_+_101162812 0.33 ENST00000353107.3
ENST00000522439.1
polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa
chr10_+_90660832 0.33 ENST00000371924.1
STAM binding protein-like 1
chr4_-_38784592 0.32 ENST00000502321.1
toll-like receptor 10
chr10_+_79793518 0.32 ENST00000440692.1
ENST00000435275.1
ENST00000372360.3
ENST00000360830.4
ribosomal protein S24
chr5_+_54455946 0.32 ENST00000503787.1
ENST00000296734.6
ENST00000515370.1
glutathione peroxidase 8 (putative)
chr4_+_130017268 0.32 ENST00000425929.1
ENST00000508673.1
ENST00000508622.1
chromosome 4 open reading frame 33
chr4_+_75480629 0.32 ENST00000380846.3
amphiregulin B
chr1_-_85156417 0.32 ENST00000422026.1
synovial sarcoma, X breakpoint 2 interacting protein
chr3_-_100566492 0.32 ENST00000528490.1
ABI family, member 3 (NESH) binding protein
chr5_-_1551802 0.32 ENST00000503113.1
CTD-2245E15.3
chr6_-_27440837 0.32 ENST00000211936.6
zinc finger protein 184
chrX_-_15353629 0.32 ENST00000333590.4
ENST00000428964.1
ENST00000542278.1
phosphatidylinositol glycan anchor biosynthesis, class A
chr10_+_91461337 0.32 ENST00000260753.4
ENST00000416354.1
ENST00000394289.2
ENST00000371728.3
kinesin family member 20B
chr17_+_3379284 0.31 ENST00000263080.2
aspartoacylase
chr8_+_94767072 0.31 ENST00000452276.1
ENST00000453321.3
ENST00000498673.1
ENST00000518319.1
transmembrane protein 67
chr12_+_21590549 0.31 ENST00000545178.1
ENST00000240651.9
pyridine nucleotide-disulphide oxidoreductase domain 1
chr15_+_35270552 0.31 ENST00000391457.2
HCG37415; PRO1914; Uncharacterized protein
chr17_+_22022437 0.31 ENST00000540040.1
MT-RNR2-like 1
chr17_+_58018269 0.30 ENST00000591035.1
Uncharacterized protein
chr7_-_35013217 0.30 ENST00000446375.1
dpy-19-like 1 (C. elegans)
chr11_+_17281900 0.30 ENST00000530527.1
nucleobindin 2
chr14_+_56127960 0.30 ENST00000553624.1
kinectin 1 (kinesin receptor)
chr4_-_103997862 0.30 ENST00000394785.3
solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2
chr10_+_91092241 0.30 ENST00000371811.4
interferon-induced protein with tetratricopeptide repeats 3
chr21_+_25801041 0.30 ENST00000453784.2
ENST00000423581.1
AP000476.1
chr10_-_112678976 0.30 ENST00000448814.1
BBSome interacting protein 1
chr3_-_27498235 0.29 ENST00000295736.5
ENST00000428386.1
ENST00000428179.1
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr15_-_56757329 0.29 ENST00000260453.3
meiosis-specific nuclear structural 1
chr11_+_12308447 0.29 ENST00000256186.2
MICAL C-terminal like
chr5_+_162887556 0.29 ENST00000393915.4
ENST00000432118.2
ENST00000358715.3
hyaluronan-mediated motility receptor (RHAMM)
chr17_+_25958174 0.29 ENST00000313648.6
ENST00000577392.1
ENST00000584661.1
ENST00000413914.2
lectin, galactoside-binding, soluble, 9
chr13_-_111522162 0.29 ENST00000538077.1
long intergenic non-protein coding RNA 346
chr6_+_3982909 0.29 ENST00000356722.3
C6ORF50
chr15_+_69706643 0.29 ENST00000352331.4
ENST00000260363.4
kinesin family member 23
chr6_+_126221034 0.28 ENST00000433571.1
nuclear receptor coactivator 7
chr10_+_127371798 0.28 ENST00000596068.1
ENST00000607914.1
ENST00000415305.2
ENST00000449693.1
RP11-383C5.3
chr13_-_88323218 0.28 ENST00000436290.2
ENST00000453832.2
ENST00000606590.1
MIR4500 host gene (non-protein coding)
chr4_-_75695366 0.28 ENST00000512743.1
betacellulin
chr6_-_153323801 0.28 ENST00000367233.5
ENST00000367231.5
ENST00000367230.1
mitochondrial translational release factor 1-like
chr6_+_37012607 0.28 ENST00000423336.1
cytochrome c oxidase subunit VIa polypeptide 1 pseudogene 2
chr1_+_87458692 0.28 ENST00000370548.2
ENST00000356813.4
Heparan sulfate 2-O-sulfotransferase 1
heparan sulfate 2-O-sulfotransferase 1
chr1_-_33116128 0.28 ENST00000436661.1
ENST00000373501.2
ENST00000341885.5
ENST00000468695.1
zinc finger and BTB domain containing 8 opposite strand
chr7_-_91764108 0.28 ENST00000450723.1
cytochrome P450, family 51, subfamily A, polypeptide 1
chr2_-_38056538 0.27 ENST00000413792.1
long intergenic non-protein coding RNA 211
chr11_+_86085778 0.27 ENST00000354755.1
ENST00000278487.3
ENST00000531271.1
ENST00000445632.2
coiled-coil domain containing 81
chr14_+_89060749 0.27 ENST00000555900.1
ENST00000406216.3
ENST00000557737.1
zinc finger CCCH-type containing 14
chr7_-_130597935 0.27 ENST00000447307.1
ENST00000418546.1
microRNA 29a
chr9_-_135230336 0.27 ENST00000224140.5
ENST00000372169.2
ENST00000393220.1
senataxin
chr6_+_30908747 0.27 ENST00000462446.1
ENST00000304311.2
diffuse panbronchiolitis critical region 1
chrX_+_49969405 0.27 ENST00000376042.1
cyclin B3
chr2_+_169658928 0.27 ENST00000317647.7
ENST00000445023.2
nitric oxide synthase trafficking
chr2_-_201753980 0.26 ENST00000443398.1
ENST00000286175.8
ENST00000409449.1
peptidylprolyl isomerase (cyclophilin)-like 3
chr2_+_202125219 0.26 ENST00000323492.7
caspase 8, apoptosis-related cysteine peptidase
chr5_+_68485433 0.26 ENST00000502689.1
centromere protein H
chr10_-_35379524 0.26 ENST00000374751.3
ENST00000374742.1
ENST00000602371.1
cullin 2
chr12_+_58335360 0.26 ENST00000300145.3
XRCC6 binding protein 1
chr8_+_62737875 0.26 ENST00000523042.1
ENST00000518593.1
ENST00000519452.1
ENST00000519967.1
RP11-705O24.1
chr12_+_79371565 0.25 ENST00000551304.1
synaptotagmin I
chr11_+_57365150 0.25 ENST00000457869.1
ENST00000340687.6
ENST00000378323.4
ENST00000378324.2
ENST00000403558.1
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr10_-_61122220 0.25 ENST00000422313.2
ENST00000435852.2
ENST00000442566.3
ENST00000373868.2
ENST00000277705.6
ENST00000373867.3
ENST00000419214.2
family with sequence similarity 13, member C
chr5_+_159848854 0.25 ENST00000517480.1
ENST00000520452.1
ENST00000393964.1
pituitary tumor-transforming 1
chr19_-_38085633 0.25 ENST00000593133.1
ENST00000590751.1
ENST00000358744.3
ENST00000328550.2
ENST00000451802.2
zinc finger protein 571
chr15_+_81225699 0.25 ENST00000560027.1
KIAA1199
chr2_-_231090344 0.24 ENST00000540870.1
ENST00000416610.1
SP110 nuclear body protein
chr10_-_14614311 0.24 ENST00000479731.1
ENST00000468492.1
family with sequence similarity 107, member B
chr2_+_109204909 0.24 ENST00000393310.1
LIM and senescent cell antigen-like domains 1
chr11_-_74408739 0.24 ENST00000529912.1
chordin-like 2
chr19_+_41281282 0.24 ENST00000263369.3
melanoma inhibitory activity
chr2_-_88125471 0.24 ENST00000398146.3
RANBP2-like and GRIP domain containing 2
chr19_+_53761545 0.24 ENST00000341702.3
vomeronasal 1 receptor 2
chr3_+_57882061 0.24 ENST00000461354.1
ENST00000466255.1
sarcolemma associated protein
chr8_-_101962777 0.24 ENST00000395951.3
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr17_+_20978854 0.24 ENST00000456235.1
AC087393.1
chr13_-_95248511 0.24 ENST00000261296.5
TDP-glucose 4,6-dehydratase
chr19_+_7580103 0.24 ENST00000596712.1
zinc finger protein 358
chr19_-_23456996 0.24 ENST00000594653.1
RP11-15H20.7
chr10_-_96829246 0.23 ENST00000371270.3
ENST00000535898.1
ENST00000539050.1
cytochrome P450, family 2, subfamily C, polypeptide 8
chr6_+_153552455 0.23 ENST00000392385.2
Uncharacterized protein; cDNA FLJ59044, highly similar to LINE-1 reverse transcriptase homolog
chr16_+_19535235 0.23 ENST00000565376.2
ENST00000396208.2
centriolar coiled coil protein 110kDa
chr7_-_16685422 0.23 ENST00000306999.2
ankyrin repeat and MYND domain containing 2
chr4_+_78829479 0.23 ENST00000504901.1
mitochondrial ribosomal protein L1
chr17_-_8066843 0.23 ENST00000404970.3
vesicle-associated membrane protein 2 (synaptobrevin 2)
chr5_+_112073544 0.23 ENST00000257430.4
ENST00000508376.2
adenomatous polyposis coli
chr17_+_75450099 0.23 ENST00000586433.1
septin 9
chr18_+_21529811 0.23 ENST00000588004.1
laminin, alpha 3
chr10_-_14050522 0.23 ENST00000342409.2
FERM domain containing 4A
chr16_+_84209539 0.23 ENST00000569735.1
dynein, axonemal, assembly factor 1
chr16_+_19535133 0.23 ENST00000396212.2
ENST00000381396.5
centriolar coiled coil protein 110kDa
chr10_-_30638090 0.23 ENST00000421701.1
ENST00000263063.4
mitochondrial poly(A) polymerase
chr4_-_103998439 0.23 ENST00000503230.1
ENST00000503818.1
solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2
chr5_+_41904431 0.23 ENST00000381647.2
chromosome 5 open reading frame 51
chr3_-_57583052 0.22 ENST00000496292.1
ENST00000489843.1
ADP-ribosylation factor 4
chr12_-_26986076 0.22 ENST00000381340.3
inositol 1,4,5-trisphosphate receptor, type 2
chr5_+_96079240 0.22 ENST00000515663.1
calpastatin
chr14_+_56127989 0.22 ENST00000555573.1
kinectin 1 (kinesin receptor)
chr3_+_14061155 0.22 ENST00000532924.1
tetra-peptide repeat homeobox-like
chr12_-_133464118 0.22 ENST00000540963.1
checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
chr15_+_69706585 0.22 ENST00000559279.1
ENST00000395392.2
kinesin family member 23
chr9_-_21305312 0.22 ENST00000259555.4
interferon, alpha 5
chr6_-_75828774 0.22 ENST00000493109.2
collagen, type XII, alpha 1
chr9_+_4679555 0.22 ENST00000381858.1
ENST00000381854.3
cell division cycle 37-like 1
chr2_-_26251481 0.22 ENST00000599234.1
Uncharacterized protein
chr4_+_79567057 0.22 ENST00000503259.1
ENST00000507802.1
long intergenic non-protein coding RNA 1094
chr10_+_105881779 0.22 ENST00000369729.3
SWI5-dependent recombination repair 1
chr1_+_227751231 0.22 ENST00000343776.5
ENST00000608949.1
ENST00000397097.3
zinc finger protein 678
chr4_+_71600144 0.22 ENST00000502653.1
RUN and FYVE domain containing 3
chr3_-_12883026 0.22 ENST00000396953.2
ENST00000457131.1
ENST00000435983.1
ENST00000273223.6
ENST00000396957.1
ENST00000429711.2
ribosomal protein L32
chr4_+_189321881 0.22 ENST00000512839.1
ENST00000513313.1
long intergenic non-protein coding RNA 1060
chr22_+_22673051 0.22 ENST00000390289.2
immunoglobulin lambda variable 5-52
chr5_-_86708833 0.21 ENST00000256897.4
cyclin H
chr11_-_14358620 0.21 ENST00000531421.1
related RAS viral (r-ras) oncogene homolog 2
chr8_+_132952112 0.21 ENST00000520362.1
ENST00000519656.1
EFR3 homolog A (S. cerevisiae)
chr1_+_240408560 0.21 ENST00000441342.1
ENST00000545751.1
formin 2
chr11_-_104905840 0.21 ENST00000526568.1
ENST00000393136.4
ENST00000531166.1
ENST00000534497.1
ENST00000527979.1
ENST00000446369.1
ENST00000353247.5
ENST00000528974.1
ENST00000533400.1
ENST00000525825.1
ENST00000436863.3
caspase 1, apoptosis-related cysteine peptidase
chr16_+_67840986 0.21 ENST00000561639.1
ENST00000567852.1
ENST00000565148.1
ENST00000388833.3
ENST00000561654.1
ENST00000431934.2
translin-associated factor X interacting protein 1
chr16_+_22518495 0.21 ENST00000541154.1
nuclear pore complex interacting protein family, member B5
chr10_-_14614095 0.21 ENST00000482277.1
ENST00000378462.1
family with sequence similarity 107, member B
chr2_+_182850743 0.21 ENST00000409702.1
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr2_+_46926048 0.21 ENST00000306503.5
suppressor of cytokine signaling 5

Network of associatons between targets according to the STRING database.

First level regulatory network of IRX3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.2 0.5 GO:0071048 nuclear mRNA surveillance of spliceosomal pre-mRNA splicing(GO:0071030) nuclear retention of unspliced pre-mRNA at the site of transcription(GO:0071048)
0.1 0.6 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.1 0.5 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.1 0.5 GO:0000912 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.1 0.9 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.1 0.5 GO:0032053 ciliary basal body organization(GO:0032053)
0.1 0.9 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.1 0.3 GO:0006533 aspartate catabolic process(GO:0006533)
0.1 0.3 GO:2000562 natural killer cell tolerance induction(GO:0002519) negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562) positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.1 0.3 GO:0033488 cholesterol biosynthetic process via 24,25-dihydrolanosterol(GO:0033488)
0.1 0.5 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 0.4 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.1 0.4 GO:0016095 polyprenol catabolic process(GO:0016095)
0.1 0.7 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.1 0.3 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.1 0.5 GO:0052055 modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.1 0.6 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.1 0.2 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.1 0.2 GO:0030070 insulin processing(GO:0030070)
0.1 0.1 GO:0071033 nuclear retention of pre-mRNA at the site of transcription(GO:0071033)
0.1 0.2 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.1 0.3 GO:0032954 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.1 0.7 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.1 GO:0001812 positive regulation of type I hypersensitivity(GO:0001812)
0.0 0.4 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.2 GO:0019236 response to pheromone(GO:0019236)
0.0 0.4 GO:0051712 positive regulation of killing of cells of other organism(GO:0051712)
0.0 0.2 GO:0070980 biphenyl catabolic process(GO:0070980)
0.0 0.1 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586)
0.0 0.2 GO:0048749 compound eye development(GO:0048749)
0.0 0.2 GO:0017198 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.0 0.3 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.0 0.2 GO:0001188 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.0 0.8 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.5 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.2 GO:0043308 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308)
0.0 0.2 GO:1904781 positive regulation of protein localization to centrosome(GO:1904781)
0.0 0.2 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.0 0.2 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 0.1 GO:0019254 amino-acid betaine catabolic process(GO:0006579) carnitine metabolic process, CoA-linked(GO:0019254)
0.0 0.2 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.0 0.3 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.2 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 0.6 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0 0.2 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.6 GO:0016075 rRNA catabolic process(GO:0016075)
0.0 0.1 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.0 0.1 GO:0032618 interleukin-15 production(GO:0032618)
0.0 0.1 GO:0032690 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.0 0.2 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.1 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 0.1 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.0 0.1 GO:1904693 midbrain morphogenesis(GO:1904693)
0.0 0.1 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.0 0.7 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.0 0.6 GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0 0.4 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.2 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0 0.2 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.0 0.1 GO:0002879 positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.0 0.1 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.1 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.0 0.5 GO:0010826 negative regulation of centrosome duplication(GO:0010826)
0.0 0.3 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.2 GO:0033504 floor plate development(GO:0033504)
0.0 0.1 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.0 0.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.1 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.0 0.8 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.4 GO:0035745 T-helper 2 cell cytokine production(GO:0035745)
0.0 0.3 GO:0009086 methionine biosynthetic process(GO:0009086)
0.0 0.1 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
0.0 0.2 GO:0070269 pyroptosis(GO:0070269)
0.0 0.2 GO:0050893 sensory processing(GO:0050893)
0.0 0.9 GO:0032201 telomere maintenance via semi-conservative replication(GO:0032201)
0.0 0.3 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 0.1 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.1 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0 0.2 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627) negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.0 0.1 GO:0046351 disaccharide biosynthetic process(GO:0046351)
0.0 0.2 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666) regulation of protein autoubiquitination(GO:1902498)
0.0 0.2 GO:0060750 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.0 0.2 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.0 0.3 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.0 0.2 GO:0008217 regulation of blood pressure(GO:0008217)
0.0 0.3 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.1 GO:1903615 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.0 0.1 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.1 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0 0.2 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.2 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.1 GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 0.1 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.2 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.2 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.3 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.2 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 0.1 GO:0003051 brain renin-angiotensin system(GO:0002035) angiotensin-mediated drinking behavior(GO:0003051)
0.0 0.3 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.2 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.4 GO:0006825 copper ion transport(GO:0006825)
0.0 0.1 GO:0048023 mammillary body development(GO:0021767) positive regulation of melanin biosynthetic process(GO:0048023) mammillary axonal complex development(GO:0061373) positive regulation of secondary metabolite biosynthetic process(GO:1900378) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.0 0.6 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.0 0.4 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.1 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.2 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.5 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 0.2 GO:0051957 positive regulation of amino acid transport(GO:0051957)
0.0 0.3 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.2 GO:0003228 atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009)
0.0 0.2 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.0 0.1 GO:0002371 dendritic cell cytokine production(GO:0002371)
0.0 0.3 GO:0035810 positive regulation of urine volume(GO:0035810)
0.0 0.1 GO:2000230 regulation of cholesterol transporter activity(GO:0060694) negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.0 0.4 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.2 GO:0060613 fat pad development(GO:0060613)
0.0 0.3 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.1 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.2 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.1 GO:0051607 defense response to virus(GO:0051607)
0.0 0.2 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.1 GO:0035966 response to unfolded protein(GO:0006986) response to topologically incorrect protein(GO:0035966)
0.0 0.3 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.2 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.1 GO:0006543 glutamine catabolic process(GO:0006543)
0.0 0.3 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.1 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.0 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
0.0 0.2 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 0.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.1 GO:0097033 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.1 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.1 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.1 GO:0051552 flavone metabolic process(GO:0051552)
0.0 0.2 GO:2000674 regulation of type B pancreatic cell apoptotic process(GO:2000674)
0.0 0.3 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.0 0.2 GO:0008595 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0 0.1 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.2 GO:0061740 protein targeting to lysosome involved in chaperone-mediated autophagy(GO:0061740)
0.0 0.1 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.0 0.2 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.0 0.0 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.2 GO:0048535 lymph node development(GO:0048535)
0.0 0.2 GO:0006662 glycerol ether metabolic process(GO:0006662)
0.0 0.0 GO:0070487 monocyte aggregation(GO:0070487)
0.0 0.4 GO:2000816 negative regulation of mitotic sister chromatid separation(GO:2000816)
0.0 0.0 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.1 0.5 GO:0071020 post-spliceosomal complex(GO:0071020)
0.1 0.8 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.1 1.6 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 0.5 GO:0097149 centralspindlin complex(GO:0097149)
0.1 0.6 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1 0.5 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.4 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 0.2 GO:0005595 collagen type XII trimer(GO:0005595)
0.1 1.1 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.1 0.2 GO:0005668 RNA polymerase transcription factor SL1 complex(GO:0005668)
0.1 0.8 GO:0034464 BBSome(GO:0034464)
0.1 0.2 GO:0032798 Swi5-Sfr1 complex(GO:0032798)
0.1 0.2 GO:0070985 TFIIK complex(GO:0070985)
0.1 0.2 GO:0097636 intrinsic component of autophagosome membrane(GO:0097636) integral component of autophagosome membrane(GO:0097637)
0.0 0.1 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.0 0.3 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.4 GO:0036128 CatSper complex(GO:0036128)
0.0 0.4 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.3 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 0.6 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.2 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.3 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.0 0.4 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.0 0.3 GO:0030891 VCB complex(GO:0030891)
0.0 0.3 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201) clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 0.3 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.2 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.0 0.3 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.2 GO:0031415 NatA complex(GO:0031415)
0.0 0.5 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.5 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.3 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.2 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.6 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.3 GO:0070938 contractile ring(GO:0070938)
0.0 0.1 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.1 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.0 1.4 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.4 GO:0071437 invadopodium(GO:0071437)
0.0 0.2 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)
0.0 0.6 GO:0031105 septin complex(GO:0031105)
0.0 0.3 GO:0036038 MKS complex(GO:0036038)
0.0 0.2 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.2 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.1 GO:0097526 U4/U6 x U5 tri-snRNP complex(GO:0046540) spliceosomal tri-snRNP complex(GO:0097526)
0.0 0.2 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.1 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.0 0.1 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.2 GO:0060091 kinocilium(GO:0060091)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0043296 apical junction complex(GO:0043296)
0.0 0.3 GO:0097342 ripoptosome(GO:0097342)
0.0 0.2 GO:0033391 chromatoid body(GO:0033391)
0.0 0.1 GO:1990425 ryanodine receptor complex(GO:1990425)
0.0 0.4 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.2 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.4 GO:0044295 axonal growth cone(GO:0044295)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0019781 NEDD8 activating enzyme activity(GO:0019781)
0.2 1.7 GO:0043515 kinetochore binding(GO:0043515)
0.1 0.4 GO:0035034 histone acetyltransferase regulator activity(GO:0035034)
0.1 0.5 GO:0032767 copper-dependent protein binding(GO:0032767)
0.1 0.3 GO:0008160 protein tyrosine phosphatase activator activity(GO:0008160)
0.1 0.4 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.1 0.6 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.1 0.4 GO:0003865 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751)
0.1 0.3 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.1 0.3 GO:0008398 sterol 14-demethylase activity(GO:0008398)
0.1 0.5 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.1 0.3 GO:0001147 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.1 1.1 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.1 0.3 GO:0002134 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.1 0.6 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1 0.5 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.1 0.7 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.1 0.2 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.1 0.4 GO:0004517 nitric-oxide synthase activity(GO:0004517) tetrahydrobiopterin binding(GO:0034617)
0.1 0.5 GO:0004771 sterol esterase activity(GO:0004771)
0.1 0.2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 0.3 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.1 0.2 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.1 0.3 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 0.1 GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.0 0.2 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.0 0.4 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.1 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
0.0 0.2 GO:0097677 STAT family protein binding(GO:0097677)
0.0 0.3 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.0 0.2 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.3 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.2 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.0 0.3 GO:0005534 galactose binding(GO:0005534)
0.0 0.1 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.0 0.3 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.1 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.0 0.3 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.1 GO:0030366 molybdopterin synthase activity(GO:0030366)
0.0 1.6 GO:0070717 poly-purine tract binding(GO:0070717)
0.0 0.3 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.3 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.1 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0 0.3 GO:0008494 translation activator activity(GO:0008494)
0.0 0.1 GO:0019863 IgE binding(GO:0019863)
0.0 0.2 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 0.1 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.0 0.2 GO:0005549 odorant binding(GO:0005549)
0.0 0.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.3 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.1 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.2 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.0 0.2 GO:0052828 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.0 0.2 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.1 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.1 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.0 0.1 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.2 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 1.3 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.1 GO:0015056 corticotrophin-releasing factor receptor activity(GO:0015056)
0.0 0.5 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.2 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.2 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.1 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.0 0.2 GO:0017018 myosin phosphatase activity(GO:0017018)
0.0 1.3 GO:0004532 exoribonuclease activity(GO:0004532)
0.0 0.2 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.1 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.7 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.6 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.1 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.1 GO:0047291 neolactotetraosylceramide alpha-2,3-sialyltransferase activity(GO:0004513) lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
0.0 0.9 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.7 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 1.2 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.3 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.1 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.1 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.0 0.1 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.0 GO:0070052 collagen V binding(GO:0070052)
0.0 0.1 GO:0050308 carbohydrate phosphatase activity(GO:0019203) sugar-phosphatase activity(GO:0050308)
0.0 0.1 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.1 GO:0001098 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.0 0.0 GO:0017129 triglyceride binding(GO:0017129)
0.0 0.3 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.0 0.2 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.2 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.0 GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.0 0.2 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 0.1 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.1 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0 0.1 GO:0033695 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 0.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.1 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.1 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.3 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.1 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.0 0.2 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.6 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.2 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.5 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.4 PID FOXO PATHWAY FoxO family signaling
0.0 0.5 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.9 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.4 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.5 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.5 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.4 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.3 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.5 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.9 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.1 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.8 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 1.3 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.7 REACTOME KINESINS Genes involved in Kinesins
0.0 0.5 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.2 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.3 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.3 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling