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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for KLF14_SP8

Z-value: 1.41

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Transcription factors associated with KLF14_SP8

Gene Symbol Gene ID Gene Info
KLF14
ENSG00000174595.4 Kruppel like factor 14
SP8
ENSG00000164651.12 Sp8 transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SP8hg19_v2_chr7_-_20826504_208265260.811.9e-01Click!

Activity profile of KLF14_SP8 motif

Sorted Z-values of KLF14_SP8 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_76649753 1.49 ENST00000603759.1
USO1
USO1 vesicle transport factor
chr1_+_228362251 1.48 ENST00000546123.1
IBA57
IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
chr19_+_42773371 1.03 ENST00000571942.2
CIC
capicua transcriptional repressor
chr19_+_47778119 1.00 ENST00000552360.2
PRR24
proline rich 24
chr6_-_33285505 0.99 ENST00000431845.2
ZBTB22
zinc finger and BTB domain containing 22
chr5_-_180237082 0.97 ENST00000506889.1
MGAT1
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr19_-_38878632 0.92 ENST00000586599.1
ENST00000334928.6
ENST00000587676.1
GGN
gametogenetin
chr19_-_1863567 0.87 ENST00000250916.4
KLF16
Kruppel-like factor 16
chr9_+_130922537 0.73 ENST00000372994.1
C9orf16
chromosome 9 open reading frame 16
chr2_+_64068116 0.73 ENST00000480679.1
UGP2
UDP-glucose pyrophosphorylase 2
chr22_+_27068704 0.72 ENST00000444388.1
ENST00000450963.1
ENST00000449017.1
CTA-211A9.5
CTA-211A9.5
chrX_-_48755030 0.71 ENST00000490755.2
ENST00000465150.2
ENST00000495490.2
TIMM17B
translocase of inner mitochondrial membrane 17 homolog B (yeast)
chr9_-_117267717 0.64 ENST00000374057.3
DFNB31
deafness, autosomal recessive 31
chr6_-_31697563 0.62 ENST00000375789.2
ENST00000416410.1
DDAH2
dimethylarginine dimethylaminohydrolase 2
chr8_+_120885949 0.58 ENST00000523492.1
ENST00000286234.5
DEPTOR
DEP domain containing MTOR-interacting protein
chrX_+_54835493 0.58 ENST00000396224.1
MAGED2
melanoma antigen family D, 2
chr11_+_64073022 0.57 ENST00000406310.1
ENST00000000442.6
ENST00000539594.1
ESRRA
estrogen-related receptor alpha
chr22_+_21771656 0.55 ENST00000407464.2
HIC2
hypermethylated in cancer 2
chr19_-_56135928 0.55 ENST00000591479.1
ENST00000325351.4
ZNF784
zinc finger protein 784
chr19_+_46009837 0.55 ENST00000589627.1
VASP
vasodilator-stimulated phosphoprotein
chr19_+_36266417 0.54 ENST00000378944.5
ENST00000007510.4
ARHGAP33
Rho GTPase activating protein 33
chr9_-_35658007 0.53 ENST00000602361.1
RMRP
RNA component of mitochondrial RNA processing endoribonuclease
chr6_-_31697977 0.53 ENST00000375787.2
DDAH2
dimethylarginine dimethylaminohydrolase 2
chr19_-_10946871 0.52 ENST00000589638.1
TMED1
transmembrane emp24 protein transport domain containing 1
chr19_+_46000506 0.52 ENST00000396737.2
PPM1N
protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative)
chr19_-_41196534 0.51 ENST00000252891.4
NUMBL
numb homolog (Drosophila)-like
chr12_-_14924056 0.51 ENST00000539745.1
HIST4H4
histone cluster 4, H4
chr19_+_45349432 0.51 ENST00000252485.4
PVRL2
poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr9_+_140317802 0.48 ENST00000341349.2
ENST00000392815.2
NOXA1
NADPH oxidase activator 1
chr15_+_31619013 0.48 ENST00000307145.3
KLF13
Kruppel-like factor 13
chr19_-_15236173 0.48 ENST00000527093.1
ILVBL
ilvB (bacterial acetolactate synthase)-like
chr15_-_72410455 0.48 ENST00000569314.1
MYO9A
myosin IXA
chr1_+_45140360 0.48 ENST00000418644.1
ENST00000458657.2
ENST00000441519.1
ENST00000535358.1
ENST00000445071.1
C1orf228
chromosome 1 open reading frame 228
chr19_-_50311896 0.47 ENST00000529634.2
FUZ
fuzzy planar cell polarity protein
chr1_+_33219592 0.47 ENST00000373481.3
KIAA1522
KIAA1522
chr19_+_11457175 0.47 ENST00000458408.1
ENST00000586451.1
ENST00000588592.1
CCDC159
coiled-coil domain containing 159
chr12_+_51632638 0.47 ENST00000549732.2
DAZAP2
DAZ associated protein 2
chr11_+_77532233 0.47 ENST00000525409.1
AAMDC
adipogenesis associated, Mth938 domain containing
chr19_+_40871734 0.47 ENST00000359274.5
PLD3
phospholipase D family, member 3
chr17_-_1619568 0.47 ENST00000571595.1
MIR22HG
MIR22 host gene (non-protein coding)
chr16_-_67217844 0.47 ENST00000563902.1
ENST00000561621.1
ENST00000290881.7
KIAA0895L
KIAA0895-like
chr17_+_43238438 0.46 ENST00000593138.1
ENST00000586681.1
HEXIM2
hexamethylene bis-acetamide inducible 2
chr7_+_100450328 0.45 ENST00000540482.1
ENST00000418037.1
ENST00000428758.1
ENST00000275729.3
ENST00000415287.1
ENST00000354161.3
ENST00000416675.1
SLC12A9
solute carrier family 12, member 9
chr19_+_1269324 0.44 ENST00000589710.1
ENST00000588230.1
ENST00000413636.2
ENST00000586472.1
ENST00000589686.1
ENST00000444172.2
ENST00000587323.1
ENST00000320936.5
ENST00000587896.1
ENST00000589235.1
ENST00000591659.1
CIRBP
cold inducible RNA binding protein
chr19_+_50015870 0.44 ENST00000599701.1
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr8_-_101322132 0.44 ENST00000523481.1
RNF19A
ring finger protein 19A, RBR E3 ubiquitin protein ligase
chr7_+_1570322 0.44 ENST00000343242.4
MAFK
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K
chr17_+_18163848 0.44 ENST00000323019.4
ENST00000578174.1
ENST00000395704.4
ENST00000395703.4
ENST00000578621.1
ENST00000579341.1
MIEF2
mitochondrial elongation factor 2
chr19_+_50145328 0.44 ENST00000360565.3
SCAF1
SR-related CTD-associated factor 1
chr19_-_50979981 0.43 ENST00000595790.1
ENST00000600100.1
FAM71E1
family with sequence similarity 71, member E1
chr11_-_69490135 0.42 ENST00000542341.1
ORAOV1
oral cancer overexpressed 1
chr2_+_71295766 0.42 ENST00000533981.1
NAGK
N-acetylglucosamine kinase
chr19_-_17622684 0.42 ENST00000596643.1
CTD-3131K8.2
CTD-3131K8.2
chr16_-_8962853 0.42 ENST00000565287.1
ENST00000311052.5
CARHSP1
calcium regulated heat stable protein 1, 24kDa
chr15_+_41056218 0.42 ENST00000260447.4
GCHFR
GTP cyclohydrolase I feedback regulator
chr6_+_31588478 0.42 ENST00000376007.4
ENST00000376033.2
PRRC2A
proline-rich coiled-coil 2A
chr12_+_58120044 0.41 ENST00000542466.2
AGAP2-AS1
AGAP2 antisense RNA 1
chr7_-_155089251 0.41 ENST00000609974.1
AC144652.1
AC144652.1
chr11_+_66234216 0.41 ENST00000349459.6
ENST00000320740.7
ENST00000524466.1
ENST00000526296.1
PELI3
pellino E3 ubiquitin protein ligase family member 3
chr9_+_136325089 0.40 ENST00000291722.7
ENST00000316948.4
ENST00000540581.1
CACFD1
calcium channel flower domain containing 1
chr19_+_56116771 0.40 ENST00000568956.1
ZNF865
zinc finger protein 865
chr19_-_40971643 0.40 ENST00000595483.1
BLVRB
biliverdin reductase B (flavin reductase (NADPH))
chr5_-_176738883 0.40 ENST00000513169.1
ENST00000423571.2
ENST00000502529.1
ENST00000427908.2
MXD3
MAX dimerization protein 3
chr9_-_99775862 0.39 ENST00000602917.1
ENST00000375223.4
HIATL2
hippocampus abundant transcript-like 2
chr19_+_36266433 0.39 ENST00000314737.5
ARHGAP33
Rho GTPase activating protein 33
chr17_-_77770830 0.39 ENST00000269385.4
CBX8
chromobox homolog 8
chr2_+_71295733 0.39 ENST00000443938.2
ENST00000244204.6
NAGK
N-acetylglucosamine kinase
chr12_+_51632666 0.38 ENST00000604900.1
DAZAP2
DAZ associated protein 2
chr9_-_130477912 0.38 ENST00000543175.1
PTRH1
peptidyl-tRNA hydrolase 1 homolog (S. cerevisiae)
chr11_-_94964210 0.38 ENST00000416495.2
ENST00000393234.1
SESN3
sestrin 3
chr3_+_181429704 0.38 ENST00000431565.2
ENST00000325404.1
SOX2
SRY (sex determining region Y)-box 2
chr19_+_38879061 0.38 ENST00000587013.1
SPRED3
sprouty-related, EVH1 domain containing 3
chr15_+_44829334 0.38 ENST00000535391.1
EIF3J
eukaryotic translation initiation factor 3, subunit J
chrX_+_68048803 0.38 ENST00000204961.4
EFNB1
ephrin-B1
chr15_+_41056255 0.37 ENST00000561160.1
ENST00000559445.1
GCHFR
GTP cyclohydrolase I feedback regulator
chr11_-_64885111 0.37 ENST00000528598.1
ENST00000310597.4
ZNHIT2
zinc finger, HIT-type containing 2
chr19_-_15236470 0.37 ENST00000533747.1
ENST00000598709.1
ENST00000534378.1
ILVBL
ilvB (bacterial acetolactate synthase)-like
chr14_+_105957402 0.37 ENST00000421892.1
ENST00000334656.7
ENST00000451719.1
ENST00000392522.3
ENST00000392523.4
ENST00000354560.6
ENST00000450383.1
C14orf80
chromosome 14 open reading frame 80
chr19_+_46144884 0.37 ENST00000593161.1
AC006132.1
chromosome 19 open reading frame 83
chr1_-_21948906 0.37 ENST00000374761.2
ENST00000599760.1
RAP1GAP
RAP1 GTPase activating protein
chr10_+_74033672 0.37 ENST00000307365.3
DDIT4
DNA-damage-inducible transcript 4
chr11_+_65383227 0.37 ENST00000355703.3
PCNXL3
pecanex-like 3 (Drosophila)
chr19_+_34287174 0.36 ENST00000587559.1
ENST00000588637.1
KCTD15
potassium channel tetramerization domain containing 15
chr19_-_36231437 0.36 ENST00000591748.1
IGFLR1
IGF-like family receptor 1
chr12_+_112451222 0.36 ENST00000552052.1
ERP29
endoplasmic reticulum protein 29
chr5_-_81046904 0.36 ENST00000515395.1
SSBP2
single-stranded DNA binding protein 2
chr19_+_54694119 0.35 ENST00000456872.1
ENST00000302937.4
ENST00000429671.2
TSEN34
TSEN34 tRNA splicing endonuclease subunit
chr17_-_58469591 0.35 ENST00000589335.1
USP32
ubiquitin specific peptidase 32
chr6_-_33267101 0.35 ENST00000497454.1
RGL2
ral guanine nucleotide dissociation stimulator-like 2
chr17_+_7338737 0.35 ENST00000323206.1
ENST00000396568.1
TMEM102
transmembrane protein 102
chr12_+_6982725 0.35 ENST00000433346.1
LRRC23
leucine rich repeat containing 23
chr4_-_13546632 0.35 ENST00000382438.5
NKX3-2
NK3 homeobox 2
chr17_-_72869086 0.35 ENST00000581530.1
ENST00000420580.2
ENST00000455107.2
ENST00000413947.2
ENST00000581219.1
ENST00000582944.1
FDXR
ferredoxin reductase
chr12_+_6833323 0.34 ENST00000544725.1
COPS7A
COP9 signalosome subunit 7A
chr20_-_3154162 0.34 ENST00000360342.3
LZTS3
Homo sapiens leucine zipper, putative tumor suppressor family member 3 (LZTS3), mRNA.
chr19_-_10679697 0.34 ENST00000335766.2
CDKN2D
cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chr7_+_2671568 0.34 ENST00000258796.7
TTYH3
tweety family member 3
chr11_+_64052454 0.34 ENST00000539833.1
GPR137
G protein-coupled receptor 137
chr22_+_30279144 0.34 ENST00000401950.2
ENST00000333027.3
ENST00000445401.1
ENST00000323630.5
ENST00000351488.3
MTMR3
myotubularin related protein 3
chr17_+_42634844 0.34 ENST00000315323.3
FZD2
frizzled family receptor 2
chr17_-_55162360 0.34 ENST00000576871.1
ENST00000576313.1
RP11-166P13.3
RP11-166P13.3
chr9_+_140500087 0.34 ENST00000371421.4
ARRDC1
arrestin domain containing 1
chr19_-_10679644 0.34 ENST00000393599.2
CDKN2D
cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chr5_-_176730733 0.34 ENST00000504395.1
RAB24
RAB24, member RAS oncogene family
chr15_-_45480153 0.34 ENST00000560471.1
ENST00000560540.1
SHF
Src homology 2 domain containing F
chr17_-_8027402 0.33 ENST00000541682.2
ENST00000317814.4
ENST00000577735.1
HES7
hes family bHLH transcription factor 7
chr20_+_35201993 0.33 ENST00000373872.4
TGIF2
TGFB-induced factor homeobox 2
chr5_-_180236811 0.33 ENST00000446023.2
MGAT1
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr19_-_51071302 0.33 ENST00000389201.3
ENST00000600381.1
LRRC4B
leucine rich repeat containing 4B
chr2_+_136499287 0.33 ENST00000415164.1
UBXN4
UBX domain protein 4
chr5_+_176074388 0.33 ENST00000310032.8
ENST00000405525.2
TSPAN17
tetraspanin 17
chr12_+_58166726 0.33 ENST00000546504.1
RP11-571M6.15
Uncharacterized protein
chr19_+_11466062 0.33 ENST00000251473.5
ENST00000591329.1
ENST00000586380.1
DKFZP761J1410
Lipid phosphate phosphatase-related protein type 2
chr7_+_75544397 0.33 ENST00000461988.1
ENST00000419840.1
POR
P450 (cytochrome) oxidoreductase
chr11_+_537494 0.33 ENST00000270115.7
LRRC56
leucine rich repeat containing 56
chr19_-_46296011 0.33 ENST00000377735.3
ENST00000270223.6
DMWD
dystrophia myotonica, WD repeat containing
chr19_+_3506261 0.32 ENST00000441788.2
FZR1
fizzy/cell division cycle 20 related 1 (Drosophila)
chr6_+_33378738 0.32 ENST00000374512.3
ENST00000374516.3
PHF1
PHD finger protein 1
chr17_+_72772621 0.32 ENST00000335464.5
ENST00000417024.2
ENST00000578764.1
ENST00000582773.1
ENST00000582330.1
TMEM104
transmembrane protein 104
chr22_-_30783075 0.32 ENST00000215798.6
RNF215
ring finger protein 215
chr7_-_73184588 0.32 ENST00000395145.2
CLDN3
claudin 3
chr19_+_36236491 0.32 ENST00000591949.1
PSENEN
presenilin enhancer gamma secretase subunit
chr12_-_6580094 0.32 ENST00000361716.3
VAMP1
vesicle-associated membrane protein 1 (synaptobrevin 1)
chr19_-_10946949 0.32 ENST00000214869.2
ENST00000591695.1
TMED1
transmembrane emp24 protein transport domain containing 1
chr19_-_15311713 0.31 ENST00000601011.1
ENST00000263388.2
NOTCH3
notch 3
chr6_-_163834852 0.31 ENST00000604200.1
CAHM
colon adenocarcinoma hypermethylated (non-protein coding)
chr19_-_56110859 0.31 ENST00000221665.3
ENST00000592585.1
FIZ1
FLT3-interacting zinc finger 1
chr1_-_154946792 0.31 ENST00000412170.1
SHC1
SHC (Src homology 2 domain containing) transforming protein 1
chr14_-_105767598 0.31 ENST00000548421.1
BRF1
BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
chr9_+_136325149 0.31 ENST00000542192.1
CACFD1
calcium channel flower domain containing 1
chr6_-_33266687 0.31 ENST00000444031.2
RGL2
ral guanine nucleotide dissociation stimulator-like 2
chrX_+_67913471 0.30 ENST00000374597.3
STARD8
StAR-related lipid transfer (START) domain containing 8
chr1_+_11333546 0.30 ENST00000376804.2
UBIAD1
UbiA prenyltransferase domain containing 1
chr19_+_50031547 0.30 ENST00000597801.1
RCN3
reticulocalbin 3, EF-hand calcium binding domain
chr6_-_31697255 0.30 ENST00000436437.1
DDAH2
dimethylarginine dimethylaminohydrolase 2
chr19_-_41196458 0.30 ENST00000598779.1
NUMBL
numb homolog (Drosophila)-like
chr17_-_2304365 0.30 ENST00000575394.1
ENST00000174618.4
MNT
MAX network transcriptional repressor
chr19_-_54693521 0.30 ENST00000391754.1
ENST00000245615.1
ENST00000431666.2
MBOAT7
membrane bound O-acyltransferase domain containing 7
chr2_-_73340146 0.30 ENST00000258098.6
RAB11FIP5
RAB11 family interacting protein 5 (class I)
chr3_+_50654821 0.29 ENST00000457064.1
MAPKAPK3
mitogen-activated protein kinase-activated protein kinase 3
chr1_+_222988406 0.29 ENST00000448808.1
ENST00000457636.1
ENST00000439440.1
RP11-452F19.3
RP11-452F19.3
chr14_-_23299009 0.29 ENST00000488800.1
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr11_+_63998006 0.29 ENST00000355040.4
DNAJC4
DnaJ (Hsp40) homolog, subfamily C, member 4
chr14_-_21562671 0.29 ENST00000554923.1
ZNF219
zinc finger protein 219
chr19_+_50084561 0.29 ENST00000246794.5
PRRG2
proline rich Gla (G-carboxyglutamic acid) 2
chr3_-_9834463 0.29 ENST00000439043.1
TADA3
transcriptional adaptor 3
chr14_-_74551096 0.29 ENST00000350259.4
ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr22_+_46476192 0.29 ENST00000443490.1
FLJ27365
hsa-mir-4763
chrX_+_48660565 0.29 ENST00000413163.2
ENST00000441703.1
ENST00000426196.1
HDAC6
histone deacetylase 6
chrX_+_47077680 0.29 ENST00000522883.1
CDK16
cyclin-dependent kinase 16
chr16_+_30935418 0.29 ENST00000338343.4
FBXL19
F-box and leucine-rich repeat protein 19
chrX_+_152990302 0.29 ENST00000218104.3
ABCD1
ATP-binding cassette, sub-family D (ALD), member 1
chr19_-_56632592 0.29 ENST00000587279.1
ENST00000270459.3
ZNF787
zinc finger protein 787
chr3_+_49507674 0.28 ENST00000431960.1
ENST00000452317.1
ENST00000435508.2
ENST00000452060.1
ENST00000428779.1
ENST00000419218.1
ENST00000430636.1
DAG1
dystroglycan 1 (dystrophin-associated glycoprotein 1)
chr17_+_46985823 0.28 ENST00000508468.2
UBE2Z
ubiquitin-conjugating enzyme E2Z
chr19_+_9945962 0.28 ENST00000587625.1
ENST00000247970.4
ENST00000588695.1
PIN1
peptidylprolyl cis/trans isomerase, NIMA-interacting 1
chr10_-_75385711 0.28 ENST00000433394.1
USP54
ubiquitin specific peptidase 54
chr19_+_11457232 0.28 ENST00000587531.1
CCDC159
coiled-coil domain containing 159
chr19_-_50370799 0.28 ENST00000600910.1
ENST00000322344.3
ENST00000600573.1
PNKP
polynucleotide kinase 3'-phosphatase
chr12_-_9102224 0.28 ENST00000543845.1
ENST00000544245.1
M6PR
mannose-6-phosphate receptor (cation dependent)
chrX_+_54834791 0.28 ENST00000218439.4
ENST00000375058.1
ENST00000375060.1
MAGED2
melanoma antigen family D, 2
chr11_-_73882249 0.28 ENST00000535954.1
C2CD3
C2 calcium-dependent domain containing 3
chr19_+_48673949 0.28 ENST00000328759.7
C19orf68
chromosome 19 open reading frame 68
chr1_+_151254738 0.27 ENST00000336715.6
ENST00000324048.5
ENST00000368879.2
ZNF687
zinc finger protein 687
chr12_+_7341759 0.27 ENST00000455147.2
ENST00000540398.1
PEX5
peroxisomal biogenesis factor 5
chr11_+_64008525 0.27 ENST00000449942.2
FKBP2
FK506 binding protein 2, 13kDa
chr15_-_32695396 0.27 ENST00000512626.2
ENST00000435655.2
GOLGA8K
AC139426.2
golgin A8 family, member K
Uncharacterized protein; cDNA FLJ52611
chr19_+_35820064 0.27 ENST00000341773.6
ENST00000600131.1
ENST00000270311.6
ENST00000595780.1
ENST00000597916.1
ENST00000593867.1
ENST00000600424.1
ENST00000599811.1
ENST00000536635.2
ENST00000085219.5
ENST00000544992.2
ENST00000419549.2
CD22
CD22 molecule
chr1_-_153940097 0.27 ENST00000413622.1
ENST00000310483.6
SLC39A1
solute carrier family 39 (zinc transporter), member 1
chr19_-_50370509 0.27 ENST00000596014.1
PNKP
polynucleotide kinase 3'-phosphatase
chr5_+_56205878 0.27 ENST00000423328.1
SETD9
SET domain containing 9
chr22_-_30722912 0.27 ENST00000215790.7
TBC1D10A
TBC1 domain family, member 10A
chr17_+_48351785 0.26 ENST00000507382.1
TMEM92
transmembrane protein 92
chr17_+_41177220 0.26 ENST00000587250.2
ENST00000544533.1
RND2
Rho family GTPase 2
chr3_+_150126101 0.26 ENST00000361875.3
ENST00000361136.2
TSC22D2
TSC22 domain family, member 2
chr11_+_64863587 0.26 ENST00000530773.1
ENST00000279281.3
ENST00000529180.1
VPS51
vacuolar protein sorting 51 homolog (S. cerevisiae)
chr6_+_33378517 0.26 ENST00000428274.1
PHF1
PHD finger protein 1
chr9_-_38069208 0.26 ENST00000377707.3
ENST00000377700.4
SHB
Src homology 2 domain containing adaptor protein B
chr7_-_128050000 0.26 ENST00000489263.1
IMPDH1
IMP (inosine 5'-monophosphate) dehydrogenase 1
chr12_+_122064398 0.26 ENST00000330079.7
ORAI1
ORAI calcium release-activated calcium modulator 1
chr16_-_3074231 0.26 ENST00000572355.1
ENST00000248089.3
ENST00000574980.1
ENST00000354679.3
ENST00000396916.1
ENST00000573842.1
HCFC1R1
host cell factor C1 regulator 1 (XPO1 dependent)
chr3_+_49840685 0.26 ENST00000333323.4
FAM212A
family with sequence similarity 212, member A
chr20_+_825275 0.26 ENST00000541082.1
FAM110A
family with sequence similarity 110, member A
chr16_+_29984962 0.25 ENST00000308893.4
TAOK2
TAO kinase 2
chr17_-_40829026 0.25 ENST00000412503.1
PLEKHH3
pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr19_-_15236562 0.25 ENST00000263383.3
ILVBL
ilvB (bacterial acetolactate synthase)-like
chr11_+_64685026 0.25 ENST00000526559.1
PPP2R5B
protein phosphatase 2, regulatory subunit B', beta
chr11_-_568369 0.25 ENST00000534540.1
ENST00000528245.1
ENST00000500447.1
ENST00000533920.1
MIR210HG
MIR210 host gene (non-protein coding)
chr17_-_40828969 0.25 ENST00000591022.1
ENST00000587627.1
ENST00000293349.6
PLEKHH3
pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr8_-_145754428 0.25 ENST00000527462.1
ENST00000313465.5
ENST00000524821.1
C8orf82
chromosome 8 open reading frame 82
chr5_-_81046841 0.25 ENST00000509013.2
ENST00000505980.1
ENST00000509053.1
SSBP2
single-stranded DNA binding protein 2
chr1_-_3528034 0.25 ENST00000356575.4
MEGF6
multiple EGF-like-domains 6
chr14_+_24899141 0.25 ENST00000556842.1
ENST00000553935.1
KHNYN
KH and NYN domain containing
chr1_+_151253991 0.25 ENST00000443959.1
ZNF687
zinc finger protein 687
chr15_-_74374891 0.25 ENST00000290438.3
GOLGA6A
golgin A6 family, member A
chr10_-_14920599 0.25 ENST00000609399.1
RP11-398C13.6
RP11-398C13.6
chr11_+_2923619 0.25 ENST00000380574.1
SLC22A18
solute carrier family 22, member 18
chr2_-_220042825 0.25 ENST00000409789.1
CNPPD1
cyclin Pas1/PHO80 domain containing 1
chr11_+_64052294 0.25 ENST00000536667.1
GPR137
G protein-coupled receptor 137
chr2_-_98280383 0.25 ENST00000289228.5
ACTR1B
ARP1 actin-related protein 1 homolog B, centractin beta (yeast)

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF14_SP8

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0043095 regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.2 1.0 GO:0006050 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.2 0.7 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.2 0.8 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.2 1.8 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.2 0.6 GO:0044778 meiotic DNA integrity checkpoint(GO:0044778)
0.2 0.8 GO:1901091 regulation of protein tetramerization(GO:1901090) negative regulation of protein tetramerization(GO:1901091) regulation of protein homotetramerization(GO:1901093) negative regulation of protein homotetramerization(GO:1901094)
0.1 0.6 GO:0070844 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.1 0.6 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.1 0.4 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
0.1 0.5 GO:0090299 regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.1 0.3 GO:1904562 phosphatidylinositol 5-phosphate metabolic process(GO:1904562)
0.1 0.3 GO:0043602 nitrate catabolic process(GO:0043602) nitric oxide catabolic process(GO:0046210)
0.1 0.5 GO:0098502 DNA dephosphorylation(GO:0098502)
0.1 0.3 GO:0043181 vacuolar sequestering(GO:0043181)
0.1 0.3 GO:0071423 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356)
0.1 0.4 GO:0098968 neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
0.1 0.3 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.1 0.2 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.1 0.4 GO:0006669 sphinganine-1-phosphate biosynthetic process(GO:0006669)
0.1 1.3 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.1 0.1 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.1 0.2 GO:0048627 myoblast development(GO:0048627)
0.1 0.2 GO:0060139 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.1 0.6 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.1 0.1 GO:0042953 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.1 0.9 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 0.2 GO:1902723 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.1 0.4 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.1 0.3 GO:0019046 release from viral latency(GO:0019046)
0.1 1.4 GO:0006527 arginine catabolic process(GO:0006527)
0.1 0.3 GO:0019859 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.1 0.3 GO:0015766 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.1 0.3 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.1 0.2 GO:0090187 positive regulation of high-density lipoprotein particle assembly(GO:0090108) positive regulation of pancreatic juice secretion(GO:0090187) positive regulation of secretion of lysosomal enzymes(GO:0090340)
0.1 0.1 GO:1903721 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
0.1 0.6 GO:0032485 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.1 0.4 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.1 0.6 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.1 1.7 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.1 0.3 GO:0003335 corneocyte development(GO:0003335)
0.1 0.1 GO:0090116 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.1 0.4 GO:0090166 Golgi disassembly(GO:0090166)
0.1 0.1 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.1 0.4 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 0.3 GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.1 0.4 GO:0007386 compartment pattern specification(GO:0007386)
0.1 0.4 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.1 0.3 GO:0009233 menaquinone metabolic process(GO:0009233)
0.1 0.2 GO:0033058 directional locomotion(GO:0033058)
0.1 0.4 GO:0021997 neural plate axis specification(GO:0021997)
0.1 0.3 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.1 0.6 GO:0048102 autophagic cell death(GO:0048102)
0.1 0.2 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.1 0.3 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.2 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
0.0 0.2 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.1 GO:0070377 regulation of ERK5 cascade(GO:0070376) negative regulation of ERK5 cascade(GO:0070377)
0.0 0.2 GO:0015862 uridine transport(GO:0015862)
0.0 0.3 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.5 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.1 GO:1903384 neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036482) positive regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902958) regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903383) negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903384)
0.0 0.2 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.0 0.1 GO:0060532 bronchus cartilage development(GO:0060532) lung smooth muscle development(GO:0061145)
0.0 0.3 GO:0003149 membranous septum morphogenesis(GO:0003149)
0.0 0.3 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.1 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.0 0.2 GO:1902269 positive regulation of polyamine transmembrane transport(GO:1902269)
0.0 0.3 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 0.1 GO:0031247 actin rod assembly(GO:0031247)
0.0 0.1 GO:0035623 renal glucose absorption(GO:0035623)
0.0 0.3 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.0 0.5 GO:2000582 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.1 GO:0009624 response to nematode(GO:0009624) insecticide metabolic process(GO:0017143) cellular alkene metabolic process(GO:0043449)
0.0 0.3 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.0 0.0 GO:0061356 Wnt protein secretion(GO:0061355) regulation of Wnt protein secretion(GO:0061356) positive regulation of Wnt protein secretion(GO:0061357)
0.0 0.3 GO:0051006 positive regulation of lipoprotein lipase activity(GO:0051006)
0.0 0.4 GO:1902363 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.0 0.2 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0 0.2 GO:0071899 regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
0.0 0.1 GO:0034471 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.0 0.1 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.0 0.1 GO:0036146 cellular response to mycotoxin(GO:0036146)
0.0 0.6 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.1 GO:0070407 oxidation-dependent protein catabolic process(GO:0070407)
0.0 0.7 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.1 GO:0033081 regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398)
0.0 0.2 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.0 0.4 GO:0097167 circadian regulation of translation(GO:0097167)
0.0 0.4 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.1 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.0 0.1 GO:1902256 apoptotic process involved in outflow tract morphogenesis(GO:0003275) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.0 0.0 GO:2000812 regulation of barbed-end actin filament capping(GO:2000812)
0.0 0.2 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.2 GO:0048295 positive regulation of isotype switching to IgE isotypes(GO:0048295)
0.0 0.2 GO:0006203 dGTP catabolic process(GO:0006203)
0.0 0.2 GO:0046618 drug export(GO:0046618)
0.0 0.1 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425)
0.0 0.2 GO:2001153 regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153)
0.0 0.3 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.2 GO:0070384 growth plate cartilage chondrocyte growth(GO:0003430) Harderian gland development(GO:0070384)
0.0 0.6 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.0 0.6 GO:0035330 regulation of hippo signaling(GO:0035330)
0.0 0.2 GO:0044332 Wnt signaling pathway involved in dorsal/ventral axis specification(GO:0044332)
0.0 0.2 GO:0036496 regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496)
0.0 0.2 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
0.0 1.1 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736)
0.0 0.2 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.0 0.1 GO:2001162 regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162)
0.0 0.5 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 0.2 GO:0043335 protein unfolding(GO:0043335)
0.0 0.2 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.1 GO:0072287 distal tubule morphogenesis(GO:0072156) metanephric distal tubule morphogenesis(GO:0072287)
0.0 0.2 GO:0035617 stress granule disassembly(GO:0035617)
0.0 0.2 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.0 0.1 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.0 0.3 GO:0010820 positive regulation of T cell chemotaxis(GO:0010820)
0.0 0.1 GO:0042732 D-xylose metabolic process(GO:0042732)
0.0 0.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.1 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.1 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.1 GO:0070370 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.0 0.1 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.0 0.4 GO:0021984 adenohypophysis development(GO:0021984)
0.0 0.4 GO:0060263 regulation of respiratory burst(GO:0060263)
0.0 0.3 GO:0072104 glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104)
0.0 0.3 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.6 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.1 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.0 0.1 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
0.0 0.4 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.0 0.1 GO:1903422 negative regulation of synaptic vesicle recycling(GO:1903422)
0.0 0.1 GO:0044029 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.0 0.1 GO:0002906 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.0 0.2 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.3 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.0 0.1 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.0 0.6 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.1 GO:0001839 neural plate morphogenesis(GO:0001839) neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.0 0.7 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.1 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.3 GO:0009304 tRNA transcription(GO:0009304)
0.0 0.1 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.0 0.3 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.0 0.2 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.1 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.0 0.1 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
0.0 0.1 GO:0002249 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
0.0 0.2 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.0 0.1 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.0 0.3 GO:2000138 positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
0.0 0.1 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.0 0.4 GO:0033015 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 0.1 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.0 0.1 GO:0034552 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.0 0.1 GO:0097283 keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172) positive regulation of keratinocyte apoptotic process(GO:1902174)
0.0 0.1 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.0 0.1 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.0 0.5 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.1 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.0 0.1 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.2 GO:0035897 proteolysis in other organism(GO:0035897)
0.0 0.2 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.3 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.0 0.3 GO:0061051 positive regulation of cell growth involved in cardiac muscle cell development(GO:0061051)
0.0 0.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.1 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.0 0.2 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 0.2 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.0 0.1 GO:0019542 acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate metabolic process(GO:0019541) propionate biosynthetic process(GO:0019542)
0.0 0.1 GO:0000255 allantoin metabolic process(GO:0000255)
0.0 0.1 GO:0072553 terminal button organization(GO:0072553)
0.0 0.1 GO:0046462 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.0 0.3 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.3 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.1 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.0 0.4 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.1 GO:1904387 cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387)
0.0 0.1 GO:0048073 regulation of eye pigmentation(GO:0048073)
0.0 0.4 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.0 GO:2000302 positive regulation of synaptic vesicle transport(GO:1902805) positive regulation of synaptic vesicle exocytosis(GO:2000302)
0.0 0.0 GO:0052255 induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528)
0.0 0.1 GO:0016240 autophagosome docking(GO:0016240)
0.0 0.2 GO:0051096 positive regulation of helicase activity(GO:0051096)
0.0 0.1 GO:0010636 positive regulation of mitochondrial fusion(GO:0010636)
0.0 0.1 GO:1904674 positive regulation of somatic stem cell population maintenance(GO:1904674)
0.0 0.1 GO:0003057 regulation of the force of heart contraction by chemical signal(GO:0003057)
0.0 0.1 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.0 GO:0090202 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.0 0.0 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0 0.1 GO:2000669 negative regulation of dendritic cell apoptotic process(GO:2000669)
0.0 0.0 GO:0006550 isoleucine catabolic process(GO:0006550)
0.0 0.1 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0 0.3 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.3 GO:0044351 macropinocytosis(GO:0044351)
0.0 0.1 GO:0033131 regulation of glucokinase activity(GO:0033131) regulation of hexokinase activity(GO:1903299)
0.0 0.1 GO:0031017 exocrine pancreas development(GO:0031017)
0.0 0.2 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
0.0 0.1 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.0 0.2 GO:0086028 bundle of His cell to Purkinje myocyte signaling(GO:0086028) bundle of His cell action potential(GO:0086043)
0.0 0.1 GO:0009794 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.0 0.0 GO:0021776 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.0 0.2 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.1 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.0 0.3 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.0 0.0 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.0 0.0 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.0 0.0 GO:0061366 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0 0.3 GO:0002433 Fc receptor mediated stimulatory signaling pathway(GO:0002431) immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
0.0 0.2 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.0 GO:0051596 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.0 GO:1904976 response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976)
0.0 0.1 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.0 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843)
0.0 0.0 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
0.0 0.2 GO:1905247 positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.0 0.3 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.1 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.0 0.3 GO:0051198 negative regulation of glycolytic process(GO:0045820) negative regulation of cofactor metabolic process(GO:0051195) negative regulation of coenzyme metabolic process(GO:0051198)
0.0 0.3 GO:0090344 negative regulation of cell aging(GO:0090344)
0.0 0.1 GO:0032079 positive regulation of endodeoxyribonuclease activity(GO:0032079)
0.0 0.1 GO:0051958 methotrexate transport(GO:0051958)
0.0 0.0 GO:1903516 regulation of single strand break repair(GO:1903516)
0.0 0.0 GO:0009227 nucleotide-sugar catabolic process(GO:0009227)
0.0 0.1 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.0 GO:1901207 regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003256) mammary gland formation(GO:0060592) regulation of heart looping(GO:1901207)
0.0 0.1 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
0.0 0.0 GO:0070221 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.0 0.2 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.1 GO:0071461 cellular response to redox state(GO:0071461)
0.0 0.2 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.0 0.4 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.1 GO:0045591 positive regulation of regulatory T cell differentiation(GO:0045591)
0.0 0.1 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.4 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.2 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.0 0.1 GO:0044375 regulation of peroxisome size(GO:0044375)
0.0 0.1 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.1 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 0.1 GO:0014004 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.0 0.1 GO:2000288 positive regulation of myoblast proliferation(GO:2000288)
0.0 0.1 GO:0098886 modification of dendritic spine(GO:0098886)
0.0 0.0 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.0 0.2 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.0 0.0 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.1 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.1 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.0 0.0 GO:0061043 regulation of vascular wound healing(GO:0061043)
0.0 0.0 GO:0060057 apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0 0.2 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.0 GO:0086021 SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021)
0.0 0.0 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.0 0.1 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 0.0 GO:0015705 iodide transport(GO:0015705)
0.0 0.1 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.0 0.0 GO:0061743 motor learning(GO:0061743)
0.0 0.1 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
0.0 0.1 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.1 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.0 0.3 GO:0060644 mammary gland epithelial cell differentiation(GO:0060644)
0.0 0.0 GO:0010887 negative regulation of cholesterol storage(GO:0010887)
0.0 0.0 GO:0006424 glutamyl-tRNA aminoacylation(GO:0006424)
0.0 0.0 GO:0051351 positive regulation of ligase activity(GO:0051351)
0.0 1.0 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.0 GO:0051459 regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0 0.1 GO:0071600 otic vesicle morphogenesis(GO:0071600)
0.0 0.4 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.0 GO:0061193 sensory organ boundary specification(GO:0008052) formation of organ boundary(GO:0010160) taste bud development(GO:0061193)
0.0 0.0 GO:0006844 acyl carnitine transport(GO:0006844) acyl carnitine transmembrane transport(GO:1902616)
0.0 0.3 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 0.0 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.1 GO:1900063 regulation of peroxisome organization(GO:1900063)
0.0 0.0 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0 0.5 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0 0.0 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.0 GO:1900193 regulation of oocyte maturation(GO:1900193)
0.0 0.0 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 0.1 GO:1904379 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.0 0.1 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 0.3 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.2 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.0 0.1 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.0 GO:0071629 cytoplasm-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071629)
0.0 0.1 GO:0032439 endosome localization(GO:0032439) ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0 0.0 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0 0.1 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.0 GO:0060032 ventral midline development(GO:0007418) smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938) notochord regression(GO:0060032)
0.0 0.1 GO:0097240 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.3 GO:0030539 male genitalia development(GO:0030539)
0.0 0.3 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.1 GO:0040034 regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.0 0.0 GO:1900155 regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
0.0 0.0 GO:1900242 regulation of synaptic vesicle endocytosis(GO:1900242)
0.0 0.0 GO:0033080 immature T cell proliferation in thymus(GO:0033080) regulation of immature T cell proliferation in thymus(GO:0033084) negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.0 0.1 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.4 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.1 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.3 GO:0039702 viral budding via host ESCRT complex(GO:0039702)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.1 0.6 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.1 0.8 GO:0030896 checkpoint clamp complex(GO:0030896)
0.1 0.3 GO:1990745 EARP complex(GO:1990745)
0.1 0.3 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.1 0.5 GO:0005587 collagen type IV trimer(GO:0005587)
0.1 0.3 GO:0071817 MMXD complex(GO:0071817)
0.0 0.4 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 0.4 GO:0070435 Shc-EGFR complex(GO:0070435)
0.0 0.1 GO:0005745 m-AAA complex(GO:0005745)
0.0 0.3 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.1 GO:0097543 ciliary inversin compartment(GO:0097543)
0.0 0.3 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.4 GO:0055028 cortical microtubule(GO:0055028)
0.0 0.5 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.2 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.2 GO:1990031 pinceau fiber(GO:1990031)
0.0 0.2 GO:1990584 cardiac Troponin complex(GO:1990584)
0.0 0.1 GO:0044393 microspike(GO:0044393)
0.0 0.2 GO:0031501 mannosyltransferase complex(GO:0031501)
0.0 0.3 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.2 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.0 0.1 GO:0030689 Noc complex(GO:0030689)
0.0 0.5 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.2 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.0 0.5 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.4 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.1 GO:0097444 spine apparatus(GO:0097444)
0.0 0.2 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.4 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.1 GO:0042585 germinal vesicle(GO:0042585)
0.0 0.3 GO:0016011 dystroglycan complex(GO:0016011)
0.0 0.1 GO:0002133 polycystin complex(GO:0002133)
0.0 0.1 GO:0044301 climbing fiber(GO:0044301)
0.0 0.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.5 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.1 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.6 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.5 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.2 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.1 GO:1990075 periciliary membrane compartment(GO:1990075)
0.0 0.1 GO:0055087 Ski complex(GO:0055087)
0.0 0.1 GO:0089701 U2AF(GO:0089701)
0.0 0.4 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 1.5 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.1 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.0 0.3 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.1 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.1 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 0.0 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.0 0.1 GO:0097629 extrinsic component of omegasome membrane(GO:0097629) extrinsic component of autophagosome membrane(GO:0097635)
0.0 0.3 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.3 GO:0036038 MKS complex(GO:0036038)
0.0 0.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.3 GO:0035869 ciliary transition zone(GO:0035869)
0.0 1.0 GO:0030286 dynein complex(GO:0030286)
0.0 0.1 GO:0043291 RAVE complex(GO:0043291)
0.0 0.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 0.6 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.3 GO:0000346 transcription export complex(GO:0000346)
0.0 0.1 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.4 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.1 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.1 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.5 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.0 GO:0032302 MutSbeta complex(GO:0032302)
0.0 0.8 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.2 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.1 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.2 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.0 GO:0034681 integrin alpha11-beta1 complex(GO:0034681)
0.0 0.2 GO:0030914 STAGA complex(GO:0030914)
0.0 0.5 GO:0016592 mediator complex(GO:0016592)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.1 GO:0030663 COPI vesicle coat(GO:0030126) COPI-coated vesicle membrane(GO:0030663)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0044549 GTP cyclohydrolase binding(GO:0044549)
0.2 1.0 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
0.2 1.4 GO:0016403 dimethylargininase activity(GO:0016403)
0.2 1.8 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.1 0.6 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.1 0.7 GO:0019770 IgG receptor activity(GO:0019770)
0.1 0.5 GO:0004074 biliverdin reductase activity(GO:0004074)
0.1 0.4 GO:0004324 ferredoxin-NADP+ reductase activity(GO:0004324) NADPH-adrenodoxin reductase activity(GO:0015039) oxidoreductase activity, acting on iron-sulfur proteins as donors(GO:0016730) oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor(GO:0016731)
0.1 0.3 GO:0047726 iron-cytochrome-c reductase activity(GO:0047726)
0.1 1.6 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 0.3 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.1 0.3 GO:0015131 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131)
0.1 0.7 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1 0.6 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.1 0.3 GO:0050816 phosphothreonine binding(GO:0050816)
0.1 0.6 GO:0003983 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.1 0.6 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.1 1.1 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.1 0.4 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 0.2 GO:0004584 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity(GO:0004584)
0.1 0.3 GO:0008515 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.1 0.2 GO:0097158 pre-mRNA intronic pyrimidine-rich binding(GO:0097158)
0.1 0.2 GO:0001133 RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding(GO:0001133)
0.1 0.2 GO:0070984 SET domain binding(GO:0070984)
0.1 0.4 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.1 0.1 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.1 0.3 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.1 0.7 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.1 0.3 GO:0001026 TFIIIB-type transcription factor activity(GO:0001026)
0.1 0.6 GO:0004969 histamine receptor activity(GO:0004969)
0.1 0.3 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 0.4 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.1 0.2 GO:0035539 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
0.1 0.3 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 0.7 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.1 0.4 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1 0.2 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.4 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.0 GO:0015227 acyl carnitine transmembrane transporter activity(GO:0015227)
0.0 0.1 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.0 0.1 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.5 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.5 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.2 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.0 0.3 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.1 GO:0016652 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.0 0.1 GO:0070362 mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364)
0.0 0.1 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)
0.0 0.5 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 0.2 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.2 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.0 0.1 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
0.0 0.1 GO:0052836 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.0 0.1 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.0 0.1 GO:0004108 citrate (Si)-synthase activity(GO:0004108) citrate synthase activity(GO:0036440)
0.0 0.3 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.3 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.3 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.1 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.1 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.0 0.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.1 GO:0051373 FATZ binding(GO:0051373)
0.0 0.2 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.1 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.1 GO:0043849 Ras palmitoyltransferase activity(GO:0043849)
0.0 0.1 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0010736 serum response element binding(GO:0010736)
0.0 0.2 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.1 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.0 0.3 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.4 GO:0035197 siRNA binding(GO:0035197)
0.0 0.2 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.0 0.1 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.0 0.1 GO:0031702 angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
0.0 0.5 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.0 0.3 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.3 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.1 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 0.2 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.1 GO:0098519 phosphoserine phosphatase activity(GO:0004647) nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.6 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.2 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.1 GO:0000404 heteroduplex DNA loop binding(GO:0000404)
0.0 0.1 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.4 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.1 GO:0047017 prostaglandin-F synthase activity(GO:0047017)
0.0 0.7 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.7 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.1 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.0 0.2 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.2 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.1 GO:0033981 D-dopachrome decarboxylase activity(GO:0033981)
0.0 0.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.4 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.1 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309)
0.0 0.1 GO:0004088 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.0 0.1 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.0 0.2 GO:0009881 photoreceptor activity(GO:0009881)
0.0 0.1 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.1 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.0 0.2 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.2 GO:0043996 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.1 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.1 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.0 0.0 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.2 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.2 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0015350 methotrexate transporter activity(GO:0015350)
0.0 0.0 GO:0004998 transferrin receptor activity(GO:0004998)
0.0 0.1 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.1 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.1 GO:0097363 protein O-GlcNAc transferase activity(GO:0097363)
0.0 0.0 GO:0047025 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.0 0.1 GO:0050656 chondroitin 4-sulfotransferase activity(GO:0047756) 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0 0.4 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.1 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 0.3 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.3 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.4 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.3 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.2 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.0 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.0 0.3 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.0 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.0 1.1 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.2 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.2 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.3 GO:0005112 Notch binding(GO:0005112)
0.0 0.2 GO:0005537 mannose binding(GO:0005537)
0.0 0.0 GO:0004818 glutamate-tRNA ligase activity(GO:0004818)
0.0 0.1 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.4 GO:0043495 protein anchor(GO:0043495)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.0 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.1 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.3 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.2 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.0 GO:0080101 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.0 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.4 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.1 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.1 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.2 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.0 GO:0008431 vitamin E binding(GO:0008431)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.1 GO:0008428 ribonuclease inhibitor activity(GO:0008428)
0.0 0.4 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.3 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.1 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.0 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 0.2 GO:0038064 collagen receptor activity(GO:0038064)
0.0 0.1 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 PID EPO PATHWAY EPO signaling pathway
0.0 1.3 PID ARF 3PATHWAY Arf1 pathway
0.0 0.4 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.1 PID IFNG PATHWAY IFN-gamma pathway
0.0 1.3 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.6 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.4 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.4 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.8 ST GAQ PATHWAY G alpha q Pathway
0.0 0.7 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.5 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.1 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.4 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.2 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.2 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.1 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.1 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.6 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.3 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.5 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.6 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.1 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.6 REACTOME SIGNALING BY NOTCH3 Genes involved in Signaling by NOTCH3
0.0 0.4 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 2.0 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.5 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.5 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.7 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.5 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.5 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.7 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.3 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.2 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.5 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.1 REACTOME NEGATIVE REGULATION OF FGFR SIGNALING Genes involved in Negative regulation of FGFR signaling
0.0 0.4 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.1 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.1 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.3 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.4 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.1 REACTOME OPSINS Genes involved in Opsins
0.0 0.3 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.3 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 1.1 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.1 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.4 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.1 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.5 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation