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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for LEF1

Z-value: 0.82

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Transcription factors associated with LEF1

Gene Symbol Gene ID Gene Info
LEF1
ENSG00000138795.5 lymphoid enhancer binding factor 1

Activity profile of LEF1 motif

Sorted Z-values of LEF1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr14_-_23791484 1.03 ENST00000594872.1
AL049829.1
Uncharacterized protein
chr4_+_76649753 0.74 ENST00000603759.1
USO1
USO1 vesicle transport factor
chr16_+_53242350 0.68 ENST00000565442.1
CHD9
chromodomain helicase DNA binding protein 9
chr11_+_110001723 0.49 ENST00000528673.1
ZC3H12C
zinc finger CCCH-type containing 12C
chr17_+_70026795 0.43 ENST00000472655.2
ENST00000538810.1
RP11-84E24.3
long intergenic non-protein coding RNA 1152
chr7_-_27219849 0.35 ENST00000396344.4
HOXA10
homeobox A10
chr17_+_76037081 0.35 ENST00000588549.1
TNRC6C
trinucleotide repeat containing 6C
chr5_+_149865377 0.35 ENST00000522491.1
NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr6_+_12008986 0.30 ENST00000491710.1
HIVEP1
human immunodeficiency virus type I enhancer binding protein 1
chr22_+_37959647 0.29 ENST00000415670.1
CDC42EP1
CDC42 effector protein (Rho GTPase binding) 1
chr5_+_175288631 0.27 ENST00000509837.1
CPLX2
complexin 2
chr2_-_97534312 0.25 ENST00000442264.1
SEMA4C
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
chr12_+_95611536 0.25 ENST00000549002.1
VEZT
vezatin, adherens junctions transmembrane protein
chr4_+_95972822 0.24 ENST00000509540.1
ENST00000440890.2
BMPR1B
bone morphogenetic protein receptor, type IB
chr3_+_182983126 0.24 ENST00000481531.1
B3GNT5
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chr10_-_18948208 0.24 ENST00000607346.1
ARL5B-AS1
ARL5B antisense RNA 1
chr4_+_96012585 0.23 ENST00000502683.1
BMPR1B
bone morphogenetic protein receptor, type IB
chr14_+_64565442 0.22 ENST00000553308.1
SYNE2
spectrin repeat containing, nuclear envelope 2
chr9_-_97356075 0.20 ENST00000375337.3
FBP2
fructose-1,6-bisphosphatase 2
chr2_-_178129551 0.20 ENST00000430047.1
NFE2L2
nuclear factor, erythroid 2-like 2
chr4_-_157892055 0.20 ENST00000422544.2
PDGFC
platelet derived growth factor C
chr12_+_54378849 0.20 ENST00000515593.1
HOXC10
homeobox C10
chr11_-_94965667 0.19 ENST00000542176.1
ENST00000278499.2
SESN3
sestrin 3
chr17_+_26369865 0.19 ENST00000582037.1
NLK
nemo-like kinase
chr6_-_127840021 0.19 ENST00000465909.2
SOGA3
SOGA family member 3
chr1_+_53793885 0.19 ENST00000445039.2
RP4-784A16.5
RP4-784A16.5
chr3_+_107244229 0.19 ENST00000456419.1
ENST00000402163.2
BBX
bobby sox homolog (Drosophila)
chr4_-_140477910 0.18 ENST00000404104.3
SETD7
SET domain containing (lysine methyltransferase) 7
chr3_-_141747950 0.18 ENST00000497579.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr7_-_139756791 0.18 ENST00000489809.1
PARP12
poly (ADP-ribose) polymerase family, member 12
chr17_+_29815013 0.18 ENST00000394744.2
RAB11FIP4
RAB11 family interacting protein 4 (class II)
chr3_-_141747439 0.18 ENST00000467667.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr21_+_17791648 0.17 ENST00000602892.1
ENST00000418813.2
ENST00000435697.1
LINC00478
long intergenic non-protein coding RNA 478
chr11_+_28724129 0.17 ENST00000513853.1
RP11-115J23.1
RP11-115J23.1
chr1_+_244998918 0.17 ENST00000366528.3
COX20
COX20 cytochrome C oxidase assembly factor
chr8_-_124553437 0.17 ENST00000517956.1
ENST00000443022.2
FBXO32
F-box protein 32
chr7_+_69064566 0.17 ENST00000403018.2
AUTS2
autism susceptibility candidate 2
chr11_-_85430356 0.17 ENST00000526999.1
SYTL2
synaptotagmin-like 2
chr13_-_74708372 0.16 ENST00000377666.4
KLF12
Kruppel-like factor 12
chr12_+_95612006 0.16 ENST00000551311.1
ENST00000546445.1
VEZT
vezatin, adherens junctions transmembrane protein
chr1_+_213123862 0.16 ENST00000366966.2
ENST00000366964.3
VASH2
vasohibin 2
chr11_-_46141338 0.16 ENST00000529782.1
ENST00000532010.1
ENST00000525438.1
ENST00000533757.1
ENST00000527782.1
PHF21A
PHD finger protein 21A
chr4_+_24661479 0.16 ENST00000569621.1
RP11-496D24.2
RP11-496D24.2
chr2_+_11679963 0.16 ENST00000263834.5
GREB1
growth regulation by estrogen in breast cancer 1
chrX_+_78003204 0.16 ENST00000435339.3
ENST00000514744.1
LPAR4
lysophosphatidic acid receptor 4
chrX_+_38420783 0.16 ENST00000422612.2
ENST00000286824.6
ENST00000545599.1
TSPAN7
tetraspanin 7
chr1_+_93645314 0.16 ENST00000343253.7
CCDC18
coiled-coil domain containing 18
chr6_-_127840336 0.16 ENST00000525778.1
SOGA3
SOGA family member 3
chr4_-_76649546 0.16 ENST00000508510.1
ENST00000509561.1
ENST00000499709.2
ENST00000511868.1
G3BP2
GTPase activating protein (SH3 domain) binding protein 2
chr2_-_118943930 0.15 ENST00000449075.1
ENST00000414886.1
ENST00000449819.1
AC093901.1
AC093901.1
chr10_+_114710516 0.15 ENST00000542695.1
ENST00000346198.4
TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr17_-_77924627 0.15 ENST00000572862.1
ENST00000573782.1
ENST00000574427.1
ENST00000570373.1
ENST00000340848.7
ENST00000576768.1
TBC1D16
TBC1 domain family, member 16
chr15_+_63335899 0.15 ENST00000561266.1
TPM1
tropomyosin 1 (alpha)
chr10_+_114710425 0.15 ENST00000352065.5
ENST00000369395.1
TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr18_-_74207146 0.15 ENST00000443185.2
ZNF516
zinc finger protein 516
chr6_-_166401442 0.15 ENST00000584179.1
LINC00473
long intergenic non-protein coding RNA 473
chr18_-_45456693 0.15 ENST00000587421.1
SMAD2
SMAD family member 2
chr10_+_114710211 0.15 ENST00000349937.2
ENST00000369397.4
TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr1_+_196743943 0.15 ENST00000471440.2
ENST00000391985.3
CFHR3
complement factor H-related 3
chr6_-_11807277 0.15 ENST00000379415.2
ADTRP
androgen-dependent TFPI-regulating protein
chr1_+_174844645 0.15 ENST00000486220.1
RABGAP1L
RAB GTPase activating protein 1-like
chr7_-_140178726 0.14 ENST00000480552.1
MKRN1
makorin ring finger protein 1
chr9_+_125795788 0.14 ENST00000373643.5
RABGAP1
RAB GTPase activating protein 1
chr3_+_186648507 0.14 ENST00000458216.1
ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr12_-_108154705 0.14 ENST00000547188.1
PRDM4
PR domain containing 4
chrX_+_100645812 0.14 ENST00000427805.2
ENST00000553110.3
ENST00000392994.3
ENST00000409338.1
ENST00000409170.3
RPL36A
RPL36A-HNRNPH2
ribosomal protein L36a
RPL36A-HNRNPH2 readthrough
chr7_+_6071007 0.14 ENST00000409061.1
ANKRD61
ankyrin repeat domain 61
chr7_+_142982023 0.14 ENST00000359333.3
ENST00000409244.1
ENST00000409541.1
ENST00000410004.1
TMEM139
transmembrane protein 139
chr5_-_16936340 0.14 ENST00000507288.1
ENST00000513610.1
MYO10
myosin X
chr1_-_78444776 0.14 ENST00000370767.1
ENST00000421641.1
FUBP1
far upstream element (FUSE) binding protein 1
chr3_-_79068138 0.14 ENST00000495273.1
ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr3_-_52719912 0.13 ENST00000420148.1
PBRM1
polybromo 1
chr1_+_6845384 0.13 ENST00000303635.7
CAMTA1
calmodulin binding transcription activator 1
chr18_+_3450161 0.13 ENST00000551402.1
ENST00000577543.1
TGIF1
TGFB-induced factor homeobox 1
chr7_-_80548493 0.13 ENST00000536800.1
SEMA3C
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr7_+_20370300 0.13 ENST00000537992.1
ITGB8
integrin, beta 8
chr7_+_151791037 0.13 ENST00000419245.1
GALNT11
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr7_+_151791074 0.13 ENST00000447796.1
GALNT11
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr4_-_140477353 0.13 ENST00000406354.1
ENST00000506866.2
SETD7
SET domain containing (lysine methyltransferase) 7
chr7_+_116451100 0.13 ENST00000464223.1
ENST00000484325.1
CAPZA2
capping protein (actin filament) muscle Z-line, alpha 2
chr14_-_51027838 0.13 ENST00000555216.1
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr4_+_170581213 0.13 ENST00000507875.1
CLCN3
chloride channel, voltage-sensitive 3
chr1_-_78444738 0.12 ENST00000436586.2
ENST00000370768.2
FUBP1
far upstream element (FUSE) binding protein 1
chr10_-_21806759 0.12 ENST00000444772.3
SKIDA1
SKI/DACH domain containing 1
chr15_+_52043813 0.12 ENST00000435126.2
TMOD2
tropomodulin 2 (neuronal)
chr2_-_161056762 0.12 ENST00000428609.2
ENST00000409967.2
ITGB6
integrin, beta 6
chr1_+_93913713 0.12 ENST00000604705.1
ENST00000370253.2
FNBP1L
formin binding protein 1-like
chr12_-_109797249 0.12 ENST00000538041.1
RP11-256L11.1
RP11-256L11.1
chr1_+_47799542 0.12 ENST00000471289.2
ENST00000450808.2
CMPK1
cytidine monophosphate (UMP-CMP) kinase 1, cytosolic
chr2_+_162087577 0.12 ENST00000439442.1
TANK
TRAF family member-associated NFKB activator
chr8_+_29953163 0.12 ENST00000518192.1
LEPROTL1
leptin receptor overlapping transcript-like 1
chrX_+_86772787 0.12 ENST00000373114.4
KLHL4
kelch-like family member 4
chr1_+_27668505 0.12 ENST00000318074.5
SYTL1
synaptotagmin-like 1
chr11_-_87908600 0.12 ENST00000531138.1
ENST00000526372.1
ENST00000243662.6
RAB38
RAB38, member RAS oncogene family
chr21_+_18811205 0.12 ENST00000440664.1
C21orf37
chromosome 21 open reading frame 37
chr5_-_137514333 0.12 ENST00000411594.2
ENST00000430331.1
BRD8
bromodomain containing 8
chr8_-_42358742 0.12 ENST00000517366.1
SLC20A2
solute carrier family 20 (phosphate transporter), member 2
chr12_-_49504449 0.12 ENST00000547675.1
LMBR1L
limb development membrane protein 1-like
chr9_-_117150303 0.12 ENST00000312033.3
AKNA
AT-hook transcription factor
chr9_-_117150243 0.12 ENST00000374088.3
AKNA
AT-hook transcription factor
chr8_+_61592073 0.12 ENST00000526846.1
CHD7
chromodomain helicase DNA binding protein 7
chr5_-_58571935 0.12 ENST00000503258.1
PDE4D
phosphodiesterase 4D, cAMP-specific
chr8_+_42873548 0.12 ENST00000533338.1
ENST00000534420.1
HOOK3
RP11-598P20.5
hook microtubule-tethering protein 3
Uncharacterized protein
chr2_+_233734994 0.12 ENST00000331342.2
C2orf82
chromosome 2 open reading frame 82
chr16_+_53241854 0.12 ENST00000565803.1
CHD9
chromodomain helicase DNA binding protein 9
chr2_+_149402989 0.11 ENST00000397424.2
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr5_+_112074029 0.11 ENST00000512211.2
APC
adenomatous polyposis coli
chr1_+_197886461 0.11 ENST00000367388.3
ENST00000337020.2
ENST00000367387.4
LHX9
LIM homeobox 9
chr6_-_127840048 0.11 ENST00000467753.1
SOGA3
SOGA family member 3
chr2_+_58655461 0.11 ENST00000429095.1
ENST00000429664.1
ENST00000452840.1
AC007092.1
long intergenic non-protein coding RNA 1122
chr17_-_47308128 0.11 ENST00000413580.1
ENST00000511066.1
PHOSPHO1
phosphatase, orphan 1
chr4_+_26165074 0.11 ENST00000512351.1
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr11_-_47521309 0.11 ENST00000535982.1
CELF1
CUGBP, Elav-like family member 1
chr16_+_67063036 0.11 ENST00000290858.6
ENST00000564034.1
CBFB
core-binding factor, beta subunit
chr8_-_22089533 0.11 ENST00000321613.3
PHYHIP
phytanoyl-CoA 2-hydroxylase interacting protein
chr17_+_19030782 0.11 ENST00000344415.4
ENST00000577213.1
GRAPL
GRB2-related adaptor protein-like
chr15_+_101402041 0.11 ENST00000558475.1
ENST00000558641.1
ENST00000559673.1
RP11-66B24.1
RP11-66B24.1
chr4_+_86699834 0.11 ENST00000395183.2
ARHGAP24
Rho GTPase activating protein 24
chr8_-_22089845 0.11 ENST00000454243.2
PHYHIP
phytanoyl-CoA 2-hydroxylase interacting protein
chr1_+_78383813 0.11 ENST00000342754.5
NEXN
nexilin (F actin binding protein)
chr11_-_8892464 0.10 ENST00000527347.1
ENST00000526241.1
ENST00000526126.1
ENST00000530938.1
ENST00000526057.1
ST5
suppression of tumorigenicity 5
chr6_+_27925019 0.10 ENST00000244623.1
OR2B6
olfactory receptor, family 2, subfamily B, member 6
chr11_-_133826852 0.10 ENST00000533871.2
ENST00000321016.8
IGSF9B
immunoglobulin superfamily, member 9B
chrX_-_128788914 0.10 ENST00000429967.1
ENST00000307484.6
APLN
apelin
chr7_-_27213893 0.10 ENST00000283921.4
HOXA10
homeobox A10
chrX_+_86772707 0.10 ENST00000373119.4
KLHL4
kelch-like family member 4
chr4_+_96012614 0.10 ENST00000264568.4
BMPR1B
bone morphogenetic protein receptor, type IB
chr11_-_46848393 0.10 ENST00000526496.1
CKAP5
cytoskeleton associated protein 5
chr13_-_67802549 0.10 ENST00000328454.5
ENST00000377865.2
PCDH9
protocadherin 9
chr13_+_39612442 0.10 ENST00000470258.1
ENST00000379600.3
NHLRC3
NHL repeat containing 3
chr2_-_160472952 0.10 ENST00000541068.2
ENST00000355831.2
ENST00000343439.5
ENST00000392782.1
BAZ2B
bromodomain adjacent to zinc finger domain, 2B
chr3_-_112360116 0.10 ENST00000206423.3
ENST00000439685.2
CCDC80
coiled-coil domain containing 80
chr10_+_115312766 0.10 ENST00000351270.3
HABP2
hyaluronan binding protein 2
chr3_-_71179988 0.10 ENST00000491238.1
FOXP1
forkhead box P1
chr18_+_55712915 0.10 ENST00000592846.1
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr5_-_65018834 0.10 ENST00000506816.1
SGTB
small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr7_-_27169801 0.10 ENST00000511914.1
HOXA4
homeobox A4
chr13_+_76210448 0.10 ENST00000377499.5
LMO7
LIM domain 7
chr4_-_157892167 0.10 ENST00000541126.1
PDGFC
platelet derived growth factor C
chr8_+_21777243 0.10 ENST00000521303.1
XPO7
exportin 7
chr3_+_20081515 0.10 ENST00000263754.4
KAT2B
K(lysine) acetyltransferase 2B
chr5_-_137514617 0.10 ENST00000254900.5
BRD8
bromodomain containing 8
chr2_-_107503558 0.10 ENST00000361686.4
ENST00000409087.3
ST6GAL2
ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
chr11_-_62432641 0.10 ENST00000528405.1
ENST00000524958.1
ENST00000525675.1
RP11-831H9.11
C11orf48
Uncharacterized protein
chromosome 11 open reading frame 48
chr10_-_14050522 0.10 ENST00000342409.2
FRMD4A
FERM domain containing 4A
chr4_-_83351294 0.10 ENST00000502762.1
HNRNPDL
heterogeneous nuclear ribonucleoprotein D-like
chr2_+_152214098 0.10 ENST00000243347.3
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr3_-_71179699 0.09 ENST00000497355.1
FOXP1
forkhead box P1
chr1_+_84629976 0.09 ENST00000446538.1
ENST00000370684.1
ENST00000436133.1
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr11_-_111649015 0.09 ENST00000529841.1
RP11-108O10.2
RP11-108O10.2
chr5_+_140248518 0.09 ENST00000398640.2
PCDHA11
protocadherin alpha 11
chr14_-_71107921 0.09 ENST00000553982.1
ENST00000500016.1
CTD-2540L5.5
CTD-2540L5.6
CTD-2540L5.5
CTD-2540L5.6
chr1_+_144339738 0.09 ENST00000538264.1
AL592284.1
Protein LOC642441
chr3_+_183353356 0.09 ENST00000242810.6
ENST00000493074.1
ENST00000437402.1
ENST00000454495.2
ENST00000473045.1
ENST00000468101.1
ENST00000427201.2
ENST00000482138.1
ENST00000454652.2
KLHL24
kelch-like family member 24
chr1_-_23670752 0.09 ENST00000302271.6
ENST00000426846.2
ENST00000427764.2
ENST00000606561.1
ENST00000374616.3
HNRNPR
heterogeneous nuclear ribonucleoprotein R
chrX_-_153095813 0.09 ENST00000544474.1
PDZD4
PDZ domain containing 4
chr17_-_44270133 0.09 ENST00000262419.6
ENST00000393476.3
KANSL1
KAT8 regulatory NSL complex subunit 1
chr11_-_111649074 0.09 ENST00000534218.1
RP11-108O10.2
RP11-108O10.2
chr7_+_150076406 0.09 ENST00000329630.5
ZNF775
zinc finger protein 775
chr16_+_67062996 0.09 ENST00000561924.2
CBFB
core-binding factor, beta subunit
chr5_-_137514288 0.09 ENST00000454473.1
ENST00000418329.1
ENST00000455658.2
ENST00000230901.5
ENST00000402931.1
BRD8
bromodomain containing 8
chr9_+_36036430 0.09 ENST00000377966.3
RECK
reversion-inducing-cysteine-rich protein with kazal motifs
chr15_+_40731920 0.09 ENST00000561234.1
BAHD1
bromo adjacent homology domain containing 1
chr11_-_64013663 0.09 ENST00000392210.2
PPP1R14B
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr13_+_76334795 0.09 ENST00000526202.1
ENST00000465261.2
LMO7
LIM domain 7
chr2_-_48132814 0.08 ENST00000316377.4
ENST00000378314.3
FBXO11
F-box protein 11
chr7_-_84121858 0.08 ENST00000448879.1
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr17_+_7533439 0.08 ENST00000441599.2
ENST00000380450.4
ENST00000416273.3
ENST00000575903.1
ENST00000576830.1
ENST00000571153.1
ENST00000575618.1
ENST00000576152.1
SHBG
sex hormone-binding globulin
chr11_-_47207390 0.08 ENST00000539589.1
ENST00000528462.1
PACSIN3
protein kinase C and casein kinase substrate in neurons 3
chr6_-_166401527 0.08 ENST00000455853.1
ENST00000584911.1
LINC00473
long intergenic non-protein coding RNA 473
chr17_+_75447326 0.08 ENST00000591088.1
SEPT9
septin 9
chr5_+_145317356 0.08 ENST00000511217.1
SH3RF2
SH3 domain containing ring finger 2
chr9_+_504674 0.08 ENST00000382297.2
KANK1
KN motif and ankyrin repeat domains 1
chr1_+_196621156 0.08 ENST00000359637.2
CFH
complement factor H
chr1_+_12538594 0.08 ENST00000543710.1
VPS13D
vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr1_-_219615984 0.08 ENST00000420762.1
RP11-95P13.1
RP11-95P13.1
chr8_-_95220775 0.08 ENST00000441892.2
ENST00000521491.1
ENST00000027335.3
CDH17
cadherin 17, LI cadherin (liver-intestine)
chr17_-_46682321 0.08 ENST00000225648.3
ENST00000484302.2
HOXB6
homeobox B6
chr3_+_57875711 0.08 ENST00000442599.2
SLMAP
sarcolemma associated protein
chr6_+_108881012 0.08 ENST00000343882.6
FOXO3
forkhead box O3
chr6_+_35704855 0.08 ENST00000288065.2
ENST00000373866.3
ARMC12
armadillo repeat containing 12
chr22_-_39150947 0.08 ENST00000411587.2
ENST00000420859.1
ENST00000452294.1
ENST00000456894.1
SUN2
Sad1 and UNC84 domain containing 2
chr4_+_160203650 0.08 ENST00000514565.1
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr6_-_24645956 0.08 ENST00000543707.1
KIAA0319
KIAA0319
chr6_+_36839616 0.08 ENST00000359359.2
ENST00000510325.2
C6orf89
chromosome 6 open reading frame 89
chr10_+_114709999 0.08 ENST00000355995.4
ENST00000545257.1
ENST00000543371.1
ENST00000536810.1
ENST00000355717.4
ENST00000538897.1
ENST00000534894.1
TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr4_-_74088800 0.08 ENST00000509867.2
ANKRD17
ankyrin repeat domain 17
chr12_-_70093235 0.08 ENST00000266661.4
BEST3
bestrophin 3
chr11_-_130184470 0.08 ENST00000357899.4
ENST00000397753.1
ZBTB44
zinc finger and BTB domain containing 44
chr1_-_202113805 0.08 ENST00000272217.2
ARL8A
ADP-ribosylation factor-like 8A
chr3_-_33686925 0.08 ENST00000485378.2
ENST00000313350.6
ENST00000487200.1
CLASP2
cytoplasmic linker associated protein 2
chr3_-_139195350 0.08 ENST00000232217.2
RBP2
retinol binding protein 2, cellular
chr6_+_135502501 0.08 ENST00000527615.1
ENST00000420123.2
ENST00000525369.1
ENST00000528774.1
ENST00000534121.1
ENST00000534044.1
ENST00000533624.1
MYB
v-myb avian myeloblastosis viral oncogene homolog
chr2_-_74780176 0.08 ENST00000409549.1
LOXL3
lysyl oxidase-like 3
chr1_+_84630367 0.08 ENST00000370680.1
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr1_+_27113963 0.08 ENST00000430292.1
PIGV
phosphatidylinositol glycan anchor biosynthesis, class V
chr9_+_97766409 0.08 ENST00000425634.2
C9orf3
chromosome 9 open reading frame 3
chr2_-_86564696 0.07 ENST00000437769.1
REEP1
receptor accessory protein 1
chr1_+_180199393 0.07 ENST00000263726.2
LHX4
LIM homeobox 4
chr9_+_128510454 0.07 ENST00000491787.3
ENST00000447726.2
PBX3
pre-B-cell leukemia homeobox 3

Network of associatons between targets according to the STRING database.

First level regulatory network of LEF1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.1 0.2 GO:0046351 disaccharide biosynthetic process(GO:0046351)
0.1 0.5 GO:1902730 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) myoblast fate commitment(GO:0048625) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.1 0.2 GO:1903452 regulation of G1 to G0 transition(GO:1903450) positive regulation of G1 to G0 transition(GO:1903452)
0.1 0.8 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.3 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.2 GO:0019056 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.0 0.1 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.0 0.3 GO:1903788 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.0 0.1 GO:0002728 negative regulation of natural killer cell cytokine production(GO:0002728)
0.0 0.1 GO:0043397 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) positive regulation of corticotropin-releasing hormone secretion(GO:0051466)
0.0 0.3 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.2 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.0 0.0 GO:0033092 positive regulation of immature T cell proliferation in thymus(GO:0033092)
0.0 0.1 GO:0035262 gonad morphogenesis(GO:0035262)
0.0 0.1 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.0 0.2 GO:0021553 olfactory nerve development(GO:0021553)
0.0 0.1 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.0 0.3 GO:0097338 response to clozapine(GO:0097338)
0.0 0.1 GO:0098582 innate vocalization behavior(GO:0098582)
0.0 0.4 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.1 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.0 0.1 GO:0007387 anterior compartment pattern formation(GO:0007387) posterior compartment specification(GO:0007388)
0.0 0.1 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076) positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.0 0.0 GO:0048864 stem cell development(GO:0048864)
0.0 0.3 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.2 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.0 0.0 GO:1904954 canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904954)
0.0 0.3 GO:0006477 protein sulfation(GO:0006477)
0.0 0.0 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0 0.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.2 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.1 GO:1990697 protein depalmitoleylation(GO:1990697)
0.0 0.1 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.1 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.0 0.1 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.0 0.2 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.0 0.0 GO:0070256 negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
0.0 0.1 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.0 0.3 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.1 GO:1901189 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.1 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.1 GO:0036515 serotonergic neuron axon guidance(GO:0036515)
0.0 0.1 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.1 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.0 0.1 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 0.0 GO:0060278 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.0 0.4 GO:0060213 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.0 0.1 GO:0051013 microtubule severing(GO:0051013)
0.0 0.0 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.0 0.2 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.1 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.2 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.0 0.0 GO:0060738 epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
0.0 0.0 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.0 0.2 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.1 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.1 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.1 GO:1903028 positive regulation of opsonization(GO:1903028)
0.0 0.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.0 GO:0045667 regulation of osteoblast differentiation(GO:0045667)
0.0 0.1 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.0 0.1 GO:0019856 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0 0.1 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.0 0.1 GO:0048022 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.0 0.1 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.2 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.1 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.3 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.2 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.1 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.0 0.1 GO:0035630 bone mineralization involved in bone maturation(GO:0035630)
0.0 0.1 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.4 GO:0060065 uterus development(GO:0060065)
0.0 0.1 GO:2000138 positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
0.0 0.0 GO:2000334 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.0 0.3 GO:0021535 cell migration in hindbrain(GO:0021535)
0.0 0.1 GO:0072709 cellular response to sorbitol(GO:0072709)
0.0 0.1 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.3 GO:0001573 ganglioside metabolic process(GO:0001573)
0.0 0.0 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
0.0 0.0 GO:0002894 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.0 0.1 GO:0009954 proximal/distal pattern formation(GO:0009954)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369) beta-catenin-TCF complex(GO:1990907)
0.1 0.2 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.1 0.1 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.0 0.5 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.1 GO:0031905 early endosome lumen(GO:0031905)
0.0 0.3 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 0.2 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.1 GO:0075341 host cell PML body(GO:0075341)
0.0 0.3 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.2 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.0 0.0 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.0 0.2 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.1 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.0 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.0 0.1 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.3 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.2 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.1 GO:0031673 H zone(GO:0031673)
0.0 0.1 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 0.1 GO:0031501 mannosyltransferase complex(GO:0031501)
0.0 0.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.8 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.5 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.3 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.0 0.6 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.2 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.0 0.1 GO:0009041 uridylate kinase activity(GO:0009041)
0.0 0.1 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.0 0.1 GO:0015322 proton-dependent oligopeptide secondary active transmembrane transporter activity(GO:0005427) secondary active oligopeptide transmembrane transporter activity(GO:0015322)
0.0 0.4 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.1 GO:0004584 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity(GO:0004584)
0.0 0.2 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.2 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.2 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:1990699 palmitoleyl hydrolase activity(GO:1990699)
0.0 0.3 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0002046 opsin binding(GO:0002046)
0.0 0.1 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.0 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.0 0.2 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.1 GO:0003947 (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity(GO:0003947)
0.0 0.1 GO:0042835 BRE binding(GO:0042835)
0.0 0.1 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.1 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.2 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.3 GO:0017049 GTP-Rho binding(GO:0017049)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID ARF 3PATHWAY Arf1 pathway
0.0 0.6 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.6 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation