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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for LHX2

Z-value: 0.50

Motif logo

Transcription factors associated with LHX2

Gene Symbol Gene ID Gene Info
ENSG00000106689.6 LIM homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
LHX2hg19_v2_chr9_+_126773880_126773895-0.712.9e-01Click!

Activity profile of LHX2 motif

Sorted Z-values of LHX2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_179318295 0.27 ENST00000442710.1
deafness, autosomal recessive 59
chr7_-_54826869 0.23 ENST00000450622.1
Sec61 gamma subunit
chr2_+_29001711 0.14 ENST00000418910.1
protein phosphatase 1, catalytic subunit, beta isozyme
chr12_-_74686314 0.14 ENST00000551210.1
ENST00000515416.2
ENST00000549905.1
RP11-81H3.2
chr4_+_70916119 0.13 ENST00000246896.3
ENST00000511674.1
histatin 1
chr12_+_6309517 0.13 ENST00000382519.4
ENST00000009180.4
CD9 molecule
chr14_+_100532771 0.13 ENST00000557153.1
Enah/Vasp-like
chr6_-_138833630 0.12 ENST00000533765.1
NHS-like 1
chr14_-_51027838 0.12 ENST00000555216.1
mitogen-activated protein kinase kinase kinase kinase 5
chr12_+_41136144 0.12 ENST00000548005.1
ENST00000552248.1
contactin 1
chr7_-_54826920 0.12 ENST00000395535.3
ENST00000352861.4
Sec61 gamma subunit
chr14_+_20187174 0.11 ENST00000557414.1
olfactory receptor, family 4, subfamily N, member 2
chrX_+_19373700 0.11 ENST00000379804.1
pyruvate dehydrogenase (lipoamide) alpha 1
chr2_+_200472779 0.11 ENST00000427045.1
ENST00000419243.1
AC093590.1
chr5_-_133702761 0.11 ENST00000521118.1
ENST00000265334.4
ENST00000435211.1
cyclin-dependent kinase-like 3
chr1_+_28527070 0.11 ENST00000596102.1
AL353354.2
chr7_-_151217166 0.10 ENST00000496004.1
Ras homolog enriched in brain
chr3_+_57882024 0.10 ENST00000494088.1
sarcolemma associated protein
chr8_+_66955648 0.10 ENST00000522619.1
DnaJ (Hsp40) homolog, subfamily C, member 5 beta
chr2_-_55276320 0.09 ENST00000357376.3
reticulon 4
chr3_-_12587055 0.09 ENST00000564146.3
chromosome 3 open reading frame 83
chr13_+_19756173 0.09 ENST00000382988.2
RP11-408E5.4
chr18_+_3247779 0.09 ENST00000578611.1
ENST00000583449.1
myosin, light chain 12A, regulatory, non-sarcomeric
chr14_+_56584414 0.09 ENST00000559044.1
pellino E3 ubiquitin protein ligase family member 2
chr9_-_125240235 0.09 ENST00000259357.2
olfactory receptor, family 1, subfamily J, member 1
chr15_-_72521017 0.09 ENST00000561609.1
pyruvate kinase, muscle
chr1_-_168464875 0.08 ENST00000422253.1
RP5-968D22.3
chr2_-_10587897 0.08 ENST00000405333.1
ENST00000443218.1
ornithine decarboxylase 1
chr8_+_92114060 0.08 ENST00000518304.1
leucine rich repeat containing 69
chr16_+_53412368 0.08 ENST00000565189.1
RP11-44F14.2
chr1_+_62439037 0.08 ENST00000545929.1
InaD-like (Drosophila)
chr2_-_198540751 0.08 ENST00000429081.1
raftlin family member 2
chr16_-_66864806 0.08 ENST00000566336.1
ENST00000394074.2
ENST00000563185.2
ENST00000359087.4
ENST00000379463.2
ENST00000565535.1
ENST00000290810.3
NEDD8 activating enzyme E1 subunit 1
chr8_+_52730143 0.08 ENST00000415643.1
Uncharacterized protein
chr14_+_56078695 0.07 ENST00000416613.1
kinectin 1 (kinesin receptor)
chr1_+_95616933 0.07 ENST00000604203.1
TMEM56-RWDD3 readthrough
chr2_-_55237484 0.07 ENST00000394609.2
reticulon 4
chr6_-_76072719 0.07 ENST00000370020.1
filamin A interacting protein 1
chr7_+_101460882 0.07 ENST00000292535.7
ENST00000549414.2
ENST00000550008.2
ENST00000546411.2
ENST00000556210.1
cut-like homeobox 1
chr10_-_37891859 0.07 ENST00000544824.1
MT-RNR2-like 7
chr2_+_109204909 0.06 ENST00000393310.1
LIM and senescent cell antigen-like domains 1
chr13_+_73632897 0.06 ENST00000377687.4
Kruppel-like factor 5 (intestinal)
chr17_-_62499334 0.06 ENST00000579996.1
DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr17_+_45000483 0.06 ENST00000576910.2
ENST00000439730.2
ENST00000393456.2
ENST00000415811.2
ENST00000575949.1
ENST00000225567.4
ENST00000572403.1
ENST00000570879.1
golgi SNAP receptor complex member 2
chr7_-_103848405 0.06 ENST00000447452.2
ENST00000545943.1
ENST00000297431.4
origin recognition complex, subunit 5
chr16_+_333152 0.06 ENST00000219406.6
ENST00000404312.1
ENST00000456379.1
protein disulfide isomerase family A, member 2
chr12_+_122688090 0.06 ENST00000324189.4
ENST00000546192.1
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
chr7_-_5998714 0.06 ENST00000539903.1
radial spoke head 10 homolog B (Chlamydomonas)
chr3_-_107099454 0.06 ENST00000593837.1
ENST00000599431.1
RP11-446H18.5
chr5_-_159546396 0.06 ENST00000523662.1
ENST00000456329.3
ENST00000307063.7
PWWP domain containing 2A
chr17_-_57229155 0.06 ENST00000584089.1
spindle and kinetochore associated complex subunit 2
chr13_+_78315466 0.05 ENST00000314070.5
ENST00000462234.1
SLAIN motif family, member 1
chrX_+_11129388 0.05 ENST00000321143.4
ENST00000380763.3
ENST00000380762.4
holocytochrome c synthase
chr3_-_191000172 0.05 ENST00000427544.2
urotensin 2B
chr13_+_78315528 0.05 ENST00000496045.1
SLAIN motif family, member 1
chr9_-_98268883 0.05 ENST00000551630.1
ENST00000548420.1
patched 1
chr2_-_231084617 0.05 ENST00000409815.2
SP110 nuclear body protein
chr6_-_131291572 0.05 ENST00000529208.1
erythrocyte membrane protein band 4.1-like 2
chr3_-_129513259 0.05 ENST00000329333.5
transmembrane and coiled-coil domain family 1
chr21_-_35014027 0.04 ENST00000399442.1
ENST00000413017.2
ENST00000445393.1
ENST00000417979.1
ENST00000426935.1
ENST00000381540.3
ENST00000361534.2
ENST00000381554.3
crystallin, zeta (quinone reductase)-like 1
chr11_-_108093329 0.04 ENST00000278612.8
nuclear protein, ataxia-telangiectasia locus
chr18_+_32556892 0.04 ENST00000591734.1
ENST00000413393.1
ENST00000589180.1
ENST00000587359.1
microtubule-associated protein, RP/EB family, member 2
chr4_+_153021899 0.04 ENST00000509332.1
ENST00000504144.1
ENST00000499452.2
RP11-18H21.1
chr18_+_68002675 0.04 ENST00000584919.1
Uncharacterized protein
chr3_+_119187785 0.04 ENST00000295588.4
ENST00000476573.1
protein O-glucosyltransferase 1
chr3_+_49977894 0.04 ENST00000433811.1
RNA binding motif protein 6
chr9_+_21440440 0.04 ENST00000276927.1
interferon, alpha 1
chr16_-_23652570 0.04 ENST00000261584.4
partner and localizer of BRCA2
chr2_-_128284020 0.04 ENST00000295321.4
ENST00000455721.2
IWS1 homolog (S. cerevisiae)
chr1_+_109265033 0.04 ENST00000445274.1
fibronectin type III domain containing 7
chr4_-_185694872 0.04 ENST00000505492.1
acyl-CoA synthetase long-chain family member 1
chr3_-_131221790 0.04 ENST00000512877.1
ENST00000264995.3
ENST00000511168.1
ENST00000425847.2
mitochondrial ribosomal protein L3
chr2_+_179317994 0.04 ENST00000375129.4
deafness, autosomal recessive 59
chr14_-_69864993 0.04 ENST00000555373.1
enhancer of rudimentary homolog (Drosophila)
chr2_+_234216454 0.04 ENST00000447536.1
ENST00000409110.1
S-antigen; retina and pineal gland (arrestin)
chr11_+_94706973 0.04 ENST00000536741.1
lysine (K)-specific demethylase 4D
chr3_-_131221771 0.04 ENST00000510154.1
ENST00000507669.1
mitochondrial ribosomal protein L3
chr2_-_175712270 0.04 ENST00000295497.7
ENST00000444394.1
chimerin 1
chr9_-_77643307 0.03 ENST00000376834.3
ENST00000376830.3
chromosome 9 open reading frame 41
chr19_+_42212501 0.03 ENST00000398599.4
carcinoembryonic antigen-related cell adhesion molecule 5
chr2_-_231084659 0.03 ENST00000258381.6
ENST00000358662.4
ENST00000455674.1
ENST00000392048.3
SP110 nuclear body protein
chr12_+_128399965 0.03 ENST00000540882.1
ENST00000542089.1
long intergenic non-protein coding RNA 507
chr19_+_42212526 0.03 ENST00000598976.1
ENST00000435837.2
ENST00000221992.6
ENST00000405816.1
Uncharacterized protein
carcinoembryonic antigen-related cell adhesion molecule 5
chrX_-_19988382 0.03 ENST00000356980.3
ENST00000379687.3
ENST00000379682.4
chromosome X open reading frame 23
chr5_-_75008244 0.03 ENST00000510798.1
ENST00000446329.2
POC5 centriolar protein
chr21_+_35014783 0.03 ENST00000381291.4
ENST00000381285.4
ENST00000399367.3
ENST00000399352.1
ENST00000399355.2
ENST00000399349.1
intersectin 1 (SH3 domain protein)
chr9_-_116061476 0.03 ENST00000441031.3
ring finger protein 183
chr19_-_44384291 0.03 ENST00000324394.6
zinc finger protein 404
chr8_-_109260897 0.03 ENST00000521297.1
ENST00000519030.1
ENST00000521440.1
ENST00000518345.1
ENST00000519627.1
ENST00000220849.5
eukaryotic translation initiation factor 3, subunit E
chr10_-_29923893 0.03 ENST00000355867.4
supervillin
chr15_+_69854027 0.03 ENST00000498938.2
RP11-279F6.1
chr9_-_139137648 0.03 ENST00000358701.5
quiescin Q6 sulfhydryl oxidase 2
chr21_+_35014706 0.03 ENST00000399353.1
ENST00000444491.1
ENST00000381318.3
intersectin 1 (SH3 domain protein)
chr5_+_180682720 0.03 ENST00000599439.1
CDNA: FLJ23158 fis, clone LNG09623; Uncharacterized protein
chr1_-_232651312 0.03 ENST00000262861.4
signal-induced proliferation-associated 1 like 2
chrX_-_11129229 0.03 ENST00000608176.1
ENST00000433747.2
ENST00000608576.1
ENST00000608916.1
RP11-120D5.1
chr6_+_3259148 0.03 ENST00000419065.2
ENST00000473000.2
ENST00000451246.2
ENST00000454610.2
proteasome (prosome, macropain) assembly chaperone 4
chr21_+_34619079 0.03 ENST00000433395.2
AP000295.9
chr1_+_145883868 0.03 ENST00000447947.2
G protein-coupled receptor 89C
chr16_+_31271274 0.03 ENST00000287497.8
ENST00000544665.3
integrin, alpha M (complement component 3 receptor 3 subunit)
chr13_+_33160553 0.02 ENST00000315596.10
PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)
chr1_-_183560011 0.02 ENST00000367536.1
neutrophil cytosolic factor 2
chr1_+_207238326 0.02 ENST00000541914.1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
chr18_-_44702668 0.02 ENST00000256433.3
immediate early response 3 interacting protein 1
chr5_-_150473127 0.02 ENST00000521001.1
TNFAIP3 interacting protein 1
chr5_+_118668846 0.02 ENST00000513374.1
tumor necrosis factor, alpha-induced protein 8
chr14_-_34420259 0.02 ENST00000250457.3
ENST00000547327.2
egl-9 family hypoxia-inducible factor 3
chr12_+_16064106 0.02 ENST00000428559.2
deoxyribose-phosphate aldolase (putative)
chr11_+_113258495 0.02 ENST00000303941.3
ankyrin repeat and kinase domain containing 1
chr1_-_147142557 0.02 ENST00000369238.6
acid phosphatase 6, lysophosphatidic
chrM_+_12331 0.02 ENST00000361567.2
mitochondrially encoded NADH dehydrogenase 5
chr10_-_116286656 0.02 ENST00000428430.1
ENST00000369266.3
ENST00000392952.3
actin binding LIM protein 1
chr8_+_76452097 0.02 ENST00000396423.2
hepatocyte nuclear factor 4, gamma
chr17_-_34308524 0.02 ENST00000293275.3
chemokine (C-C motif) ligand 16
chr6_+_130339710 0.02 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
l(3)mbt-like 3 (Drosophila)
chr6_+_112408768 0.02 ENST00000368656.2
ENST00000604268.1
family with sequence similarity 229, member B
chr5_-_156536126 0.02 ENST00000522593.1
hepatitis A virus cellular receptor 2
chrX_+_18725758 0.02 ENST00000472826.1
ENST00000544635.1
ENST00000496075.2
protein phosphatase, EF-hand calcium binding domain 1
chr12_+_27932803 0.02 ENST00000381271.2
kelch-like family member 42
chr10_+_124320156 0.02 ENST00000338354.3
ENST00000344338.3
ENST00000330163.4
ENST00000368909.3
ENST00000368955.3
ENST00000368956.2
deleted in malignant brain tumors 1
chr12_+_12510352 0.02 ENST00000298571.6
loss of heterozygosity, 12, chromosomal region 1
chr16_-_18887627 0.02 ENST00000563235.1
SMG1 phosphatidylinositol 3-kinase-related kinase
chr1_+_160709055 0.02 ENST00000368043.3
ENST00000368042.3
ENST00000458602.2
ENST00000458104.2
SLAM family member 7
chr14_-_78083112 0.02 ENST00000216484.2
serine palmitoyltransferase, long chain base subunit 2
chr2_+_234627424 0.02 ENST00000373409.3
UDP glucuronosyltransferase 1 family, polypeptide A4
chr4_-_57253587 0.02 ENST00000513376.1
ENST00000602986.1
ENST00000434343.2
ENST00000451613.1
ENST00000205214.6
ENST00000502617.1
aminoadipate-semialdehyde dehydrogenase
chr4_-_89951028 0.02 ENST00000506913.1
family with sequence similarity 13, member A
chr4_+_128554081 0.01 ENST00000335251.6
ENST00000296461.5
inturned planar cell polarity protein
chr1_+_219347203 0.01 ENST00000366927.3
lysophospholipase-like 1
chr14_-_23395623 0.01 ENST00000556043.1
protein arginine methyltransferase 5
chr12_+_128399917 0.01 ENST00000544645.1
long intergenic non-protein coding RNA 507
chr2_-_175712479 0.01 ENST00000443238.1
chimerin 1
chr10_-_69597828 0.01 ENST00000339758.7
DnaJ (Hsp40) homolog, subfamily C, member 12
chr9_+_108320392 0.01 ENST00000602661.1
ENST00000223528.2
ENST00000448551.2
ENST00000540160.1
fukutin
chr8_+_28748765 0.01 ENST00000355231.5
homeobox containing 1
chr2_+_87769459 0.01 ENST00000414030.1
ENST00000437561.1
long intergenic non-protein coding RNA 152
chr3_+_57881966 0.01 ENST00000495364.1
sarcolemma associated protein
chr2_-_99279928 0.01 ENST00000414521.2
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr17_+_17082842 0.01 ENST00000579361.1
myosin phosphatase Rho interacting protein
chr3_-_98619999 0.01 ENST00000449482.1
discoidin, CUB and LCCL domain containing 2
chrX_-_20074895 0.01 ENST00000543767.1
MAP7 domain containing 2
chr1_+_182419261 0.01 ENST00000294854.8
ENST00000542961.1
regulator of G-protein signaling like 1
chr2_-_198540719 0.01 ENST00000295049.4
raftlin family member 2
chr11_-_31531121 0.01 ENST00000532287.1
ENST00000526776.1
ENST00000534812.1
ENST00000529749.1
ENST00000278200.1
ENST00000530023.1
ENST00000533642.1
IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr11_+_24518723 0.01 ENST00000336930.6
ENST00000529015.1
ENST00000533227.1
leucine zipper protein 2
chr13_+_24844857 0.01 ENST00000409126.1
ENST00000343003.6
spermatogenesis associated 13
chr1_-_75100539 0.01 ENST00000420661.2
chromosome 1 open reading frame 173
chr2_+_102953608 0.01 ENST00000311734.2
ENST00000409584.1
interleukin 1 receptor-like 1
chr10_+_69865866 0.01 ENST00000354393.2
myopalladin
chr6_+_125524785 0.01 ENST00000392482.2
tumor protein D52-like 1
chr8_+_110656344 0.01 ENST00000499579.1
Uncharacterized protein
chrX_-_138724677 0.01 ENST00000370573.4
ENST00000338585.6
ENST00000370576.4
MCF.2 cell line derived transforming sequence
chr6_+_123038689 0.01 ENST00000354275.2
ENST00000368446.1
protein kinase (cAMP-dependent, catalytic) inhibitor beta
chr4_-_1670632 0.01 ENST00000461064.1
family with sequence similarity 53, member A
chr2_+_145780739 0.00 ENST00000597173.1
ENST00000602108.1
ENST00000420472.1
testis expressed 41 (non-protein coding)
chr2_+_210517895 0.00 ENST00000447185.1
microtubule-associated protein 2
chr10_-_14372870 0.00 ENST00000357447.2
FERM domain containing 4A
chr14_-_38036271 0.00 ENST00000556024.1
RP11-356O9.2
chr3_-_100551141 0.00 ENST00000478235.1
ENST00000471901.1
ABI family, member 3 (NESH) binding protein
chr13_+_24844979 0.00 ENST00000454083.1
spermatogenesis associated 13
chr8_-_19459993 0.00 ENST00000454498.2
ENST00000520003.1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr11_+_120973375 0.00 ENST00000264037.2
tectorin alpha
chr7_-_99717463 0.00 ENST00000437822.2
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr1_+_41448820 0.00 ENST00000372616.1
CTP synthase 1
chr16_+_88636875 0.00 ENST00000569435.1
zinc finger CCCH-type containing 18
chr5_+_179921344 0.00 ENST00000261951.4
CCR4-NOT transcription complex, subunit 6
chr11_+_31391381 0.00 ENST00000465995.1
ENST00000536040.1
DnaJ (Hsp40) homolog, subfamily C, member 24
chr10_-_90712520 0.00 ENST00000224784.6
actin, alpha 2, smooth muscle, aorta
chr12_-_49245916 0.00 ENST00000552512.1
ENST00000551468.1
DEAD (Asp-Glu-Ala-Asp) box polypeptide 23
chr8_+_92082424 0.00 ENST00000285420.4
ENST00000404789.3
OTU domain containing 6B
chr1_+_84630574 0.00 ENST00000413538.1
ENST00000417530.1
protein kinase, cAMP-dependent, catalytic, beta

Network of associatons between targets according to the STRING database.

First level regulatory network of LHX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.1 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.0 0.0 GO:0097198 histone H3-K36 trimethylation(GO:0097198)
0.0 0.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.1 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.1 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.1 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.1 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.1 GO:0009414 response to water deprivation(GO:0009414)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:1902912 pyruvate kinase complex(GO:1902912)
0.0 0.1 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.1 GO:0042587 glycogen granule(GO:0042587)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.3 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.1 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.0 0.1 GO:0019781 NEDD8 activating enzyme activity(GO:0019781)
0.0 0.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.0 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.0 0.1 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)