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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for MNT_HEY1_HEY2

Z-value: 0.70

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Transcription factors associated with MNT_HEY1_HEY2

Gene Symbol Gene ID Gene Info
MNT
ENSG00000070444.10 MAX network transcriptional repressor
HEY1
ENSG00000164683.12 hes related family bHLH transcription factor with YRPW motif 1
HEY2
ENSG00000135547.4 hes related family bHLH transcription factor with YRPW motif 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HEY2hg19_v2_chr6_+_126070726_1260707680.485.2e-01Click!
HEY1hg19_v2_chr8_-_80680078_806801010.346.6e-01Click!
MNThg19_v2_chr17_-_2304365_23044120.227.8e-01Click!

Activity profile of MNT_HEY1_HEY2 motif

Sorted Z-values of MNT_HEY1_HEY2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_112451222 0.79 ENST00000552052.1
ERP29
endoplasmic reticulum protein 29
chr2_-_232328867 0.67 ENST00000453992.1
ENST00000417652.1
ENST00000454824.1
NCL
nucleolin
chr20_-_3219359 0.63 ENST00000437836.2
SLC4A11
solute carrier family 4, sodium borate transporter, member 11
chr3_+_186648507 0.50 ENST00000458216.1
ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr15_+_44084040 0.50 ENST00000249786.4
SERF2
small EDRK-rich factor 2
chr4_-_1107306 0.47 ENST00000433731.2
ENST00000333673.5
ENST00000382968.5
RNF212
ring finger protein 212
chr19_+_7587555 0.43 ENST00000601003.1
MCOLN1
mucolipin 1
chr19_+_1261106 0.43 ENST00000588411.1
CIRBP
cold inducible RNA binding protein
chr15_+_44084503 0.43 ENST00000409960.2
ENST00000409646.1
ENST00000594896.1
ENST00000339624.5
ENST00000409291.1
ENST00000402131.1
ENST00000403425.1
ENST00000430901.1
SERF2
small EDRK-rich factor 2
chr17_-_6915646 0.37 ENST00000574377.1
ENST00000399541.2
ENST00000399540.2
ENST00000575727.1
ENST00000573939.1
AC027763.2
Uncharacterized protein
chr16_+_50280020 0.37 ENST00000564965.1
ADCY7
adenylate cyclase 7
chr15_+_82555125 0.35 ENST00000566205.1
ENST00000339465.5
ENST00000569120.1
ENST00000566861.1
FAM154B
family with sequence similarity 154, member B
chr12_+_64845864 0.33 ENST00000538890.1
TBK1
TANK-binding kinase 1
chr6_-_163834852 0.32 ENST00000604200.1
CAHM
colon adenocarcinoma hypermethylated (non-protein coding)
chr9_-_100684769 0.31 ENST00000455506.1
ENST00000375117.4
C9orf156
chromosome 9 open reading frame 156
chr2_+_232575168 0.29 ENST00000440384.1
PTMA
prothymosin, alpha
chr19_+_5681153 0.29 ENST00000579559.1
ENST00000577222.1
HSD11B1L
RPL36
hydroxysteroid (11-beta) dehydrogenase 1-like
ribosomal protein L36
chr7_-_155089251 0.29 ENST00000609974.1
AC144652.1
AC144652.1
chr1_+_154193643 0.28 ENST00000456325.1
UBAP2L
ubiquitin associated protein 2-like
chr1_+_150254936 0.28 ENST00000447007.1
ENST00000369095.1
ENST00000369094.1
C1orf51
chromosome 1 open reading frame 51
chr14_-_54955376 0.28 ENST00000553333.1
GMFB
glia maturation factor, beta
chr5_-_133706695 0.28 ENST00000521755.1
ENST00000523054.1
ENST00000435240.2
ENST00000609654.1
ENST00000536186.1
ENST00000609383.1
CDKL3
cyclin-dependent kinase-like 3
chr16_-_4588469 0.25 ENST00000588381.1
ENST00000563332.2
CDIP1
cell death-inducing p53 target 1
chr10_-_46090334 0.25 ENST00000395771.3
ENST00000319836.3
MARCH8
membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
chr11_-_69490135 0.25 ENST00000542341.1
ORAOV1
oral cancer overexpressed 1
chr12_-_9102224 0.24 ENST00000543845.1
ENST00000544245.1
M6PR
mannose-6-phosphate receptor (cation dependent)
chr7_-_130597935 0.24 ENST00000447307.1
ENST00000418546.1
MIR29B1
microRNA 29a
chr3_-_52719912 0.24 ENST00000420148.1
PBRM1
polybromo 1
chr2_+_232575128 0.23 ENST00000412128.1
PTMA
prothymosin, alpha
chr6_-_151773232 0.23 ENST00000444024.1
ENST00000367303.4
RMND1
required for meiotic nuclear division 1 homolog (S. cerevisiae)
chr10_-_46089939 0.23 ENST00000453980.3
MARCH8
membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
chr10_+_46222648 0.22 ENST00000336378.4
ENST00000540872.1
ENST00000537517.1
ENST00000374362.2
ENST00000359860.4
ENST00000420848.1
FAM21C
family with sequence similarity 21, member C
chr2_+_30670209 0.22 ENST00000497423.1
ENST00000476535.1
LCLAT1
lysocardiolipin acyltransferase 1
chr1_-_26233423 0.21 ENST00000357865.2
STMN1
stathmin 1
chr10_-_6019455 0.21 ENST00000530685.1
ENST00000397255.3
ENST00000379971.1
ENST00000528354.1
ENST00000397250.2
ENST00000429135.2
IL15RA
interleukin 15 receptor, alpha
chr1_+_154193325 0.21 ENST00000428931.1
ENST00000441890.1
ENST00000271877.7
ENST00000412596.1
ENST00000368504.1
ENST00000437652.1
UBAP2L
ubiquitin associated protein 2-like
chr3_-_149688971 0.21 ENST00000498307.1
ENST00000489155.1
PFN2
profilin 2
chr8_+_109455830 0.21 ENST00000524143.1
EMC2
ER membrane protein complex subunit 2
chr7_+_100464760 0.21 ENST00000200457.4
TRIP6
thyroid hormone receptor interactor 6
chr3_+_122785895 0.21 ENST00000316218.7
PDIA5
protein disulfide isomerase family A, member 5
chr10_+_51827648 0.20 ENST00000351071.6
ENST00000314664.7
ENST00000282633.5
FAM21A
family with sequence similarity 21, member A
chr16_-_18937072 0.20 ENST00000569122.1
SMG1
SMG1 phosphatidylinositol 3-kinase-related kinase
chr14_-_92572894 0.20 ENST00000532032.1
ENST00000506466.1
ENST00000555381.1
ENST00000557311.1
ENST00000554592.1
ENST00000554672.1
ENST00000553491.1
ENST00000556220.1
ENST00000502250.1
ENST00000503767.1
ENST00000393287.5
ENST00000340660.6
ENST00000545170.1
ENST00000429774.2
ATXN3
ataxin 3
chr10_-_31320860 0.20 ENST00000436087.2
ENST00000442986.1
ENST00000413025.1
ENST00000452305.1
ZNF438
zinc finger protein 438
chr12_+_95611536 0.20 ENST00000549002.1
VEZT
vezatin, adherens junctions transmembrane protein
chr2_+_121493717 0.20 ENST00000418323.1
GLI2
GLI family zinc finger 2
chr12_-_6715808 0.20 ENST00000545584.1
CHD4
chromodomain helicase DNA binding protein 4
chr5_-_176738883 0.20 ENST00000513169.1
ENST00000423571.2
ENST00000502529.1
ENST00000427908.2
MXD3
MAX dimerization protein 3
chr7_-_27170352 0.19 ENST00000428284.2
ENST00000360046.5
HOXA4
homeobox A4
chr1_-_26232951 0.19 ENST00000426559.2
ENST00000455785.2
STMN1
stathmin 1
chr5_-_178054014 0.19 ENST00000520957.1
CLK4
CDC-like kinase 4
chr7_+_23636992 0.19 ENST00000307471.3
ENST00000409765.1
CCDC126
coiled-coil domain containing 126
chr4_-_17783135 0.19 ENST00000265018.3
FAM184B
family with sequence similarity 184, member B
chr1_-_111746966 0.19 ENST00000369752.5
DENND2D
DENN/MADD domain containing 2D
chr4_+_129732419 0.19 ENST00000510308.1
PHF17
jade family PHD finger 1
chr22_-_29663690 0.18 ENST00000406335.1
RHBDD3
rhomboid domain containing 3
chr12_+_64845660 0.18 ENST00000331710.5
TBK1
TANK-binding kinase 1
chr9_-_100684845 0.18 ENST00000375119.3
C9orf156
chromosome 9 open reading frame 156
chr10_-_31320840 0.18 ENST00000375311.1
ZNF438
zinc finger protein 438
chr2_+_46926326 0.18 ENST00000394861.2
SOCS5
suppressor of cytokine signaling 5
chr12_-_123380610 0.18 ENST00000535765.1
VPS37B
vacuolar protein sorting 37 homolog B (S. cerevisiae)
chr19_-_51142540 0.18 ENST00000598997.1
SYT3
synaptotagmin III
chrX_+_102469997 0.18 ENST00000372695.5
ENST00000372691.3
BEX4
brain expressed, X-linked 4
chr6_-_90529418 0.17 ENST00000439638.1
ENST00000369393.3
ENST00000428876.1
MDN1
MDN1, midasin homolog (yeast)
chr10_+_180643 0.17 ENST00000509513.2
ENST00000397959.3
ZMYND11
zinc finger, MYND-type containing 11
chr4_-_83295296 0.17 ENST00000507010.1
ENST00000503822.1
HNRNPD
heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
chr12_+_122356488 0.17 ENST00000397454.2
WDR66
WD repeat domain 66
chr9_+_130159433 0.17 ENST00000451404.1
SLC2A8
solute carrier family 2 (facilitated glucose transporter), member 8
chr10_-_6019552 0.17 ENST00000379977.3
ENST00000397251.3
ENST00000397248.2
IL15RA
interleukin 15 receptor, alpha
chr10_+_180405 0.16 ENST00000439456.1
ENST00000397962.3
ENST00000309776.4
ENST00000381602.4
ZMYND11
zinc finger, MYND-type containing 11
chr12_+_9102632 0.16 ENST00000539240.1
KLRG1
killer cell lectin-like receptor subfamily G, member 1
chr11_-_116968987 0.16 ENST00000434315.2
ENST00000292055.4
ENST00000375288.1
ENST00000542607.1
ENST00000445177.1
ENST00000375300.1
ENST00000446921.2
SIK3
SIK family kinase 3
chr1_+_11866270 0.16 ENST00000376497.3
ENST00000376487.3
ENST00000376496.3
CLCN6
chloride channel, voltage-sensitive 6
chr9_-_135545380 0.16 ENST00000544003.1
DDX31
DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
chr1_-_110613276 0.16 ENST00000369792.4
ALX3
ALX homeobox 3
chr11_+_65686728 0.16 ENST00000312515.2
ENST00000525501.1
DRAP1
DR1-associated protein 1 (negative cofactor 2 alpha)
chr5_-_150138246 0.16 ENST00000518015.1
DCTN4
dynactin 4 (p62)
chr8_+_6566206 0.16 ENST00000518327.1
AGPAT5
1-acylglycerol-3-phosphate O-acyltransferase 5
chr2_-_198364581 0.15 ENST00000428204.1
HSPD1
heat shock 60kDa protein 1 (chaperonin)
chr4_+_76649753 0.15 ENST00000603759.1
USO1
USO1 vesicle transport factor
chr17_-_58469591 0.15 ENST00000589335.1
USP32
ubiquitin specific peptidase 32
chr6_-_56112235 0.15 ENST00000370817.3
COL21A1
collagen, type XXI, alpha 1
chr19_-_47164386 0.15 ENST00000391916.2
ENST00000410105.2
DACT3
dishevelled-binding antagonist of beta-catenin 3
chr7_-_92465868 0.15 ENST00000424848.2
CDK6
cyclin-dependent kinase 6
chr21_-_16374688 0.15 ENST00000411932.1
NRIP1
nuclear receptor interacting protein 1
chr14_-_91884150 0.15 ENST00000553403.1
CCDC88C
coiled-coil domain containing 88C
chr3_+_133292851 0.15 ENST00000503932.1
CDV3
CDV3 homolog (mouse)
chr15_-_52971544 0.15 ENST00000566768.1
ENST00000561543.1
FAM214A
family with sequence similarity 214, member A
chr17_-_41465674 0.15 ENST00000592135.1
ENST00000587874.1
ENST00000588654.1
ENST00000592094.1
LINC00910
long intergenic non-protein coding RNA 910
chr11_-_69490073 0.15 ENST00000535657.1
ENST00000539414.1
ENST00000536870.1
ENST00000538554.2
ENST00000279147.4
ORAOV1
oral cancer overexpressed 1
chr16_-_54963026 0.14 ENST00000560208.1
ENST00000557792.1
CRNDE
colorectal neoplasia differentially expressed (non-protein coding)
chr2_+_173420697 0.14 ENST00000282077.3
ENST00000392571.2
ENST00000410055.1
PDK1
pyruvate dehydrogenase kinase, isozyme 1
chr16_+_88636875 0.14 ENST00000569435.1
ZC3H18
zinc finger CCCH-type containing 18
chr8_+_38614754 0.14 ENST00000521642.1
TACC1
transforming, acidic coiled-coil containing protein 1
chr2_+_240323439 0.14 ENST00000428471.1
ENST00000413029.1
AC062017.1
Uncharacterized protein
chr2_+_198365122 0.14 ENST00000604458.1
HSPE1-MOB4
HSPE1-MOB4 readthrough
chr1_-_180991978 0.14 ENST00000542060.1
ENST00000258301.5
STX6
syntaxin 6
chr1_+_43637996 0.14 ENST00000528956.1
ENST00000529956.1
WDR65
WD repeat domain 65
chr19_+_46144884 0.14 ENST00000593161.1
AC006132.1
chromosome 19 open reading frame 83
chr8_-_124553437 0.14 ENST00000517956.1
ENST00000443022.2
FBXO32
F-box protein 32
chr11_+_18720316 0.14 ENST00000280734.2
TMEM86A
transmembrane protein 86A
chr1_-_151319654 0.13 ENST00000430227.1
ENST00000412774.1
RFX5
regulatory factor X, 5 (influences HLA class II expression)
chr1_-_231376836 0.13 ENST00000451322.1
C1orf131
chromosome 1 open reading frame 131
chr8_-_144679602 0.13 ENST00000526710.1
EEF1D
eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
chr9_+_37120536 0.13 ENST00000336755.5
ENST00000534928.1
ENST00000322831.6
ZCCHC7
zinc finger, CCHC domain containing 7
chr3_-_45883558 0.13 ENST00000445698.1
ENST00000296135.6
LZTFL1
leucine zipper transcription factor-like 1
chr2_-_68384603 0.13 ENST00000406245.2
ENST00000409164.1
ENST00000295121.6
WDR92
WD repeat domain 92
chr11_-_61684962 0.13 ENST00000394836.2
RAB3IL1
RAB3A interacting protein (rabin3)-like 1
chr18_+_9136758 0.13 ENST00000383440.2
ENST00000262126.4
ENST00000577992.1
ANKRD12
ankyrin repeat domain 12
chr11_+_133902547 0.13 ENST00000529070.1
RP11-713P17.3
RP11-713P17.3
chr1_+_246729815 0.13 ENST00000366511.1
CNST
consortin, connexin sorting protein
chr2_+_111878483 0.13 ENST00000308659.8
ENST00000357757.2
ENST00000393253.2
ENST00000337565.5
ENST00000393256.3
BCL2L11
BCL2-like 11 (apoptosis facilitator)
chr2_+_201171268 0.13 ENST00000423749.1
ENST00000428692.1
ENST00000457757.1
ENST00000453663.1
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr19_-_19739321 0.13 ENST00000588461.1
LPAR2
lysophosphatidic acid receptor 2
chr1_-_78149041 0.13 ENST00000414381.1
ENST00000370798.1
ZZZ3
zinc finger, ZZ-type containing 3
chrX_+_16804544 0.13 ENST00000380122.5
ENST00000398155.4
TXLNG
taxilin gamma
chr3_-_150481218 0.13 ENST00000482706.1
SIAH2
siah E3 ubiquitin protein ligase 2
chr11_+_72929402 0.12 ENST00000393596.2
P2RY2
purinergic receptor P2Y, G-protein coupled, 2
chr22_+_29469100 0.12 ENST00000327813.5
ENST00000407188.1
KREMEN1
kringle containing transmembrane protein 1
chr17_-_17109579 0.12 ENST00000321560.3
PLD6
phospholipase D family, member 6
chr7_-_150675372 0.12 ENST00000262186.5
KCNH2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr9_+_96793076 0.12 ENST00000375360.3
PTPDC1
protein tyrosine phosphatase domain containing 1
chr7_-_42951509 0.12 ENST00000438029.1
ENST00000432637.1
ENST00000447342.1
ENST00000431882.2
ENST00000350427.4
ENST00000425683.1
C7orf25
chromosome 7 open reading frame 25
chr19_+_1407733 0.12 ENST00000592453.1
DAZAP1
DAZ associated protein 1
chr7_-_27205136 0.12 ENST00000396345.1
ENST00000343483.6
HOXA9
homeobox A9
chr2_-_176867534 0.12 ENST00000445472.1
KIAA1715
KIAA1715
chr1_-_222886526 0.12 ENST00000541237.1
AIDA
axin interactor, dorsalization associated
chr3_-_52719810 0.12 ENST00000424867.1
ENST00000394830.3
ENST00000431678.1
ENST00000450271.1
PBRM1
polybromo 1
chr19_+_50031547 0.12 ENST00000597801.1
RCN3
reticulocalbin 3, EF-hand calcium binding domain
chr9_+_37079968 0.12 ENST00000588403.1
RP11-220I1.1
RP11-220I1.1
chr1_+_28261621 0.12 ENST00000549094.1
SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
chr11_-_64013663 0.12 ENST00000392210.2
PPP1R14B
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr4_+_9446156 0.12 ENST00000334879.1
DEFB131
defensin, beta 131
chr2_-_40006357 0.11 ENST00000505747.1
THUMPD2
THUMP domain containing 2
chr2_+_208576259 0.11 ENST00000392209.3
CCNYL1
cyclin Y-like 1
chr5_-_1799864 0.11 ENST00000510999.1
MRPL36
mitochondrial ribosomal protein L36
chr10_-_16859442 0.11 ENST00000602389.1
ENST00000345264.5
RSU1
Ras suppressor protein 1
chr1_+_244998918 0.11 ENST00000366528.3
COX20
COX20 cytochrome C oxidase assembly factor
chr2_+_56411131 0.11 ENST00000407595.2
CCDC85A
coiled-coil domain containing 85A
chr10_-_120840309 0.11 ENST00000369144.3
EIF3A
eukaryotic translation initiation factor 3, subunit A
chr1_+_45140360 0.11 ENST00000418644.1
ENST00000458657.2
ENST00000441519.1
ENST00000535358.1
ENST00000445071.1
C1orf228
chromosome 1 open reading frame 228
chr11_+_72929319 0.11 ENST00000393597.2
ENST00000311131.2
P2RY2
purinergic receptor P2Y, G-protein coupled, 2
chr11_+_75479850 0.11 ENST00000376262.3
ENST00000604733.1
DGAT2
diacylglycerol O-acyltransferase 2
chr8_-_144442136 0.11 ENST00000519148.1
TOP1MT
topoisomerase (DNA) I, mitochondrial
chr16_-_4897266 0.11 ENST00000591451.1
ENST00000436648.5
ENST00000381983.3
ENST00000588297.1
ENST00000321919.9
GLYR1
glyoxylate reductase 1 homolog (Arabidopsis)
chr8_+_17354587 0.11 ENST00000494857.1
ENST00000522656.1
SLC7A2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr1_-_52520828 0.11 ENST00000610127.1
TXNDC12
thioredoxin domain containing 12 (endoplasmic reticulum)
chr4_+_129732467 0.11 ENST00000413543.2
PHF17
jade family PHD finger 1
chr2_+_198365095 0.11 ENST00000409468.1
HSPE1
heat shock 10kDa protein 1
chr7_+_99070464 0.11 ENST00000331410.5
ENST00000483089.1
ENST00000448667.1
ENST00000493485.1
ZNF789
zinc finger protein 789
chr4_+_164415855 0.11 ENST00000508268.1
TMA16
translation machinery associated 16 homolog (S. cerevisiae)
chr6_+_73331918 0.11 ENST00000402622.2
ENST00000355635.3
ENST00000403813.2
ENST00000414165.2
KCNQ5
potassium voltage-gated channel, KQT-like subfamily, member 5
chr8_-_144442094 0.11 ENST00000521193.1
ENST00000520950.1
TOP1MT
topoisomerase (DNA) I, mitochondrial
chr9_+_129987488 0.11 ENST00000446764.1
GARNL3
GTPase activating Rap/RanGAP domain-like 3
chr3_+_113666748 0.11 ENST00000330212.3
ENST00000498275.1
ZDHHC23
zinc finger, DHHC-type containing 23
chr15_+_41913690 0.11 ENST00000563576.1
MGA
MGA, MAX dimerization protein
chr12_-_122750957 0.11 ENST00000451053.2
VPS33A
vacuolar protein sorting 33 homolog A (S. cerevisiae)
chr1_-_26232522 0.11 ENST00000399728.1
STMN1
stathmin 1
chr4_+_183065793 0.11 ENST00000512480.1
TENM3
teneurin transmembrane protein 3
chr3_+_52720187 0.11 ENST00000474423.1
GNL3
guanine nucleotide binding protein-like 3 (nucleolar)
chr18_+_9913977 0.11 ENST00000400000.2
ENST00000340541.4
VAPA
VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
chr19_+_49458107 0.11 ENST00000539787.1
ENST00000345358.7
ENST00000391871.3
ENST00000415969.2
ENST00000354470.3
ENST00000506183.1
ENST00000293288.8
BAX
BCL2-associated X protein
chr1_+_109642799 0.11 ENST00000602755.1
SCARNA2
small Cajal body-specific RNA 2
chrX_-_20134713 0.11 ENST00000452324.3
MAP7D2
MAP7 domain containing 2
chr11_+_65686802 0.11 ENST00000376991.2
DRAP1
DR1-associated protein 1 (negative cofactor 2 alpha)
chr1_-_11866034 0.10 ENST00000376590.3
MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr7_-_27169801 0.10 ENST00000511914.1
HOXA4
homeobox A4
chrX_+_38420783 0.10 ENST00000422612.2
ENST00000286824.6
ENST00000545599.1
TSPAN7
tetraspanin 7
chr4_-_146101304 0.10 ENST00000447906.2
OTUD4
OTU domain containing 4
chr2_+_187350973 0.10 ENST00000544130.1
ZC3H15
zinc finger CCCH-type containing 15
chr9_-_35691017 0.10 ENST00000378292.3
TPM2
tropomyosin 2 (beta)
chr6_+_33257427 0.10 ENST00000463584.1
PFDN6
prefoldin subunit 6
chr4_-_83351294 0.10 ENST00000502762.1
HNRNPDL
heterogeneous nuclear ribonucleoprotein D-like
chr9_-_135819987 0.10 ENST00000298552.3
ENST00000403810.1
TSC1
tuberous sclerosis 1
chr17_+_48450575 0.10 ENST00000338165.4
ENST00000393271.2
ENST00000511519.2
EME1
essential meiotic structure-specific endonuclease 1
chr14_-_39901618 0.10 ENST00000554932.1
ENST00000298097.7
FBXO33
F-box protein 33
chr2_-_40006289 0.10 ENST00000260619.6
ENST00000454352.2
THUMPD2
THUMP domain containing 2
chr21_+_45527171 0.10 ENST00000291576.7
ENST00000456705.1
PWP2
PWP2 periodic tryptophan protein homolog (yeast)
chr16_-_81129845 0.10 ENST00000569885.1
ENST00000566566.1
GCSH
glycine cleavage system protein H (aminomethyl carrier)
chr9_+_37079888 0.10 ENST00000429493.1
ENST00000593237.1
ENST00000588557.1
ENST00000430809.1
ENST00000592157.1
RP11-220I1.1
RP11-220I1.1
chr19_-_36545128 0.10 ENST00000538849.1
THAP8
THAP domain containing 8
chr6_+_33257346 0.10 ENST00000374606.5
ENST00000374610.2
ENST00000374607.1
PFDN6
prefoldin subunit 6
chrX_+_55744228 0.10 ENST00000262850.7
RRAGB
Ras-related GTP binding B
chr2_+_233562015 0.10 ENST00000427233.1
ENST00000373566.3
ENST00000373563.4
ENST00000428883.1
ENST00000456491.1
ENST00000409480.1
ENST00000421433.1
ENST00000425040.1
ENST00000430720.1
ENST00000409547.1
ENST00000423659.1
ENST00000409196.3
ENST00000409451.3
ENST00000429187.1
ENST00000440945.1
GIGYF2
GRB10 interacting GYF protein 2
chr10_-_104474128 0.10 ENST00000260746.5
ARL3
ADP-ribosylation factor-like 3
chr12_+_104235229 0.10 ENST00000551650.1
RP11-650K20.3
Uncharacterized protein
chr7_-_32931623 0.10 ENST00000452926.1
KBTBD2
kelch repeat and BTB (POZ) domain containing 2
chr19_-_46974741 0.10 ENST00000313683.10
ENST00000602246.1
PNMAL1
paraneoplastic Ma antigen family-like 1
chr8_+_142402089 0.10 ENST00000521578.1
ENST00000520105.1
ENST00000523147.1
PTP4A3
protein tyrosine phosphatase type IVA, member 3
chr19_-_13030071 0.10 ENST00000293695.7
SYCE2
synaptonemal complex central element protein 2
chr4_-_103997455 0.10 ENST00000362026.3
ENST00000503103.1
SLC9B2
solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2
chr17_+_27573875 0.10 ENST00000225387.3
CRYBA1
crystallin, beta A1
chr12_-_6756559 0.10 ENST00000536350.1
ENST00000414226.2
ENST00000546114.1
ACRBP
acrosin binding protein
chr2_-_232329186 0.10 ENST00000322723.4
NCL
nucleolin
chr13_-_52027134 0.10 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
INTS6
integrator complex subunit 6
chr20_-_61051026 0.10 ENST00000252997.2
GATA5
GATA binding protein 5
chr8_+_120885949 0.10 ENST00000523492.1
ENST00000286234.5
DEPTOR
DEP domain containing MTOR-interacting protein
chr5_-_142784101 0.10 ENST00000503201.1
ENST00000502892.1
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr5_-_131132658 0.10 ENST00000514667.1
ENST00000511848.1
ENST00000510461.1
CTC-432M15.3
FNIP1
Folliculin-interacting protein 1
folliculin interacting protein 1
chr8_+_109455845 0.10 ENST00000220853.3
EMC2
ER membrane protein complex subunit 2

Network of associatons between targets according to the STRING database.

First level regulatory network of MNT_HEY1_HEY2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0043335 protein unfolding(GO:0043335)
0.1 0.1 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 0.4 GO:0044778 meiotic DNA integrity checkpoint(GO:0044778)
0.1 0.5 GO:0006311 meiotic gene conversion(GO:0006311)
0.1 0.3 GO:1990828 response to putrescine(GO:1904585) cellular response to putrescine(GO:1904586) hepatocyte dedifferentiation(GO:1990828)
0.1 0.6 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.1 0.6 GO:0044565 dendritic cell proliferation(GO:0044565)
0.1 0.5 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.1 0.2 GO:0021776 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.1 0.1 GO:0010520 regulation of reciprocal meiotic recombination(GO:0010520) positive regulation of reciprocal meiotic recombination(GO:0010845)
0.1 0.2 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.1 0.2 GO:1902263 apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
0.1 0.2 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 0.1 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.7 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.0 0.1 GO:1903565 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.0 0.1 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.0 0.2 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.1 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.0 0.2 GO:0015862 uridine transport(GO:0015862)
0.0 0.2 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
0.0 0.1 GO:0061461 lysine import(GO:0034226) L-lysine import(GO:0061461) L-lysine import into cell(GO:1903410)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.1 GO:0046168 glycerol-3-phosphate catabolic process(GO:0046168)
0.0 0.1 GO:0002368 B cell cytokine production(GO:0002368) protein import into mitochondrial intermembrane space(GO:0045041)
0.0 0.2 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.0 0.2 GO:0072553 terminal button organization(GO:0072553)
0.0 0.2 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
0.0 0.1 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.0 0.1 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.0 0.2 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.1 GO:0060730 regulation of intestinal epithelial structure maintenance(GO:0060730)
0.0 0.1 GO:1905246 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.0 0.1 GO:0071400 cellular response to oleic acid(GO:0071400)
0.0 0.1 GO:0010636 positive regulation of mitochondrial fusion(GO:0010636)
0.0 0.1 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.0 0.2 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 0.2 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.2 GO:1904327 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.0 0.1 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.1 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.3 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.0 0.2 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.0 0.1 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.0 0.0 GO:1904886 beta-catenin destruction complex disassembly(GO:1904886)
0.0 0.1 GO:0000921 septin ring assembly(GO:0000921) septin ring organization(GO:0031106)
0.0 0.1 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 0.1 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.0 0.2 GO:0033183 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.0 0.1 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.0 0.1 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
0.0 0.1 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.0 0.6 GO:0042044 fluid transport(GO:0042044)
0.0 0.1 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.0 0.2 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.0 GO:0045815 positive regulation of gene expression, epigenetic(GO:0045815)
0.0 0.1 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.0 0.1 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 0.5 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.1 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 0.1 GO:0090649 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.0 0.1 GO:0034471 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.0 0.4 GO:0071361 cellular response to ethanol(GO:0071361)
0.0 0.1 GO:0043697 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.0 0.4 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.1 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.0 0.1 GO:0006272 leading strand elongation(GO:0006272)
0.0 0.0 GO:0000961 negative regulation of mitochondrial RNA catabolic process(GO:0000961)
0.0 0.1 GO:1903936 response to sodium arsenite(GO:1903935) cellular response to sodium arsenite(GO:1903936)
0.0 0.1 GO:0008343 adult feeding behavior(GO:0008343)
0.0 0.2 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.0 0.0 GO:0030908 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.0 0.1 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.1 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.1 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 0.0 GO:0072034 renal vesicle induction(GO:0072034)
0.0 0.3 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.2 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.1 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.0 0.1 GO:0044417 translocation of peptides or proteins into host(GO:0042000) translocation of peptides or proteins into host cell cytoplasm(GO:0044053) translocation of molecules into host(GO:0044417) translocation of peptides or proteins into other organism involved in symbiotic interaction(GO:0051808) translocation of molecules into other organism involved in symbiotic interaction(GO:0051836)
0.0 0.1 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.1 GO:1902683 positive regulation of long-term neuronal synaptic plasticity(GO:0048170) regulation of receptor localization to synapse(GO:1902683)
0.0 0.1 GO:1904764 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.0 0.1 GO:0046833 positive regulation of RNA export from nucleus(GO:0046833)
0.0 0.0 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
0.0 0.1 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.0 GO:0060903 positive regulation of meiosis I(GO:0060903)
0.0 0.1 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.1 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.0 0.2 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.1 GO:0032053 ciliary basal body organization(GO:0032053)
0.0 0.1 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.0 0.1 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.1 GO:0006294 nucleotide-excision repair, preincision complex assembly(GO:0006294)
0.0 0.0 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.1 GO:1902074 response to salt(GO:1902074)
0.0 0.0 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.0 0.0 GO:2000980 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 0.0 GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.0 0.1 GO:0051612 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.0 GO:2000506 negative regulation of energy homeostasis(GO:2000506)
0.0 0.1 GO:0014042 positive regulation of neuron maturation(GO:0014042)
0.0 0.0 GO:0048320 inhibition of neuroepithelial cell differentiation(GO:0002085) axial mesoderm formation(GO:0048320)
0.0 0.1 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.0 0.0 GO:0043309 regulation of eosinophil degranulation(GO:0043309) positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.0 0.1 GO:0071494 cellular response to UV-C(GO:0071494)
0.0 0.2 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.0 0.0 GO:0046351 disaccharide biosynthetic process(GO:0046351)
0.0 0.1 GO:0016240 autophagosome docking(GO:0016240)
0.0 0.1 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.0 GO:0060021 palate development(GO:0060021)
0.0 0.1 GO:0090031 positive regulation of steroid hormone biosynthetic process(GO:0090031)
0.0 0.0 GO:1904378 maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.0 0.0 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.1 GO:1902957 negative regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902957)
0.0 0.0 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.0 0.0 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.2 GO:0006265 DNA topological change(GO:0006265)
0.0 0.0 GO:0070781 response to biotin(GO:0070781)
0.0 0.1 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.0 0.2 GO:0050812 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0 0.0 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.1 GO:0048254 snoRNA localization(GO:0048254)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0001534 radial spoke(GO:0001534)
0.1 0.2 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.3 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.1 GO:0070985 TFIIK complex(GO:0070985)
0.0 0.1 GO:0043614 multi-eIF complex(GO:0043614)
0.0 0.2 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.7 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.2 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.1 GO:0005960 glycine cleavage complex(GO:0005960)
0.0 0.2 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.0 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.0 GO:0005713 recombination nodule(GO:0005713)
0.0 0.0 GO:0043235 receptor complex(GO:0043235)
0.0 0.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.2 GO:0033263 CORVET complex(GO:0033263)
0.0 0.1 GO:0097543 ciliary inversin compartment(GO:0097543)
0.0 0.1 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 0.1 GO:0034448 EGO complex(GO:0034448)
0.0 0.1 GO:0035101 FACT complex(GO:0035101)
0.0 0.2 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.2 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.2 GO:0031298 replication fork protection complex(GO:0031298)
0.0 0.1 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 0.1 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.0 0.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.0 GO:0036398 TCR signalosome(GO:0036398)
0.0 0.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 0.1 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.2 GO:0033391 chromatoid body(GO:0033391)
0.0 0.2 GO:0030139 endocytic vesicle(GO:0030139)
0.0 0.1 GO:0033503 HULC complex(GO:0033503)
0.0 0.1 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.1 GO:0034457 Mpp10 complex(GO:0034457)
0.0 0.2 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.1 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.0 GO:0001740 Barr body(GO:0001740)
0.0 0.1 GO:0000801 central element(GO:0000801)
0.0 0.4 GO:0030904 retromer complex(GO:0030904)
0.0 0.1 GO:0046696 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907) lipopolysaccharide receptor complex(GO:0046696)
0.0 0.4 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.1 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.0 0.0 GO:0009346 citrate lyase complex(GO:0009346)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.1 0.2 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.6 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.1 0.3 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.1 GO:0098770 FBXO family protein binding(GO:0098770)
0.0 0.5 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 1.1 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.1 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0 0.1 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.4 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.1 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.0 0.1 GO:0034584 piRNA binding(GO:0034584)
0.0 0.2 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.1 GO:0097158 pre-mRNA intronic pyrimidine-rich binding(GO:0097158)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.1 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.0 0.1 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.1 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.0 0.1 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.0 0.1 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.1 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.0 0.2 GO:0071253 connexin binding(GO:0071253)
0.0 0.1 GO:0005289 high-affinity basic amino acid transmembrane transporter activity(GO:0005287) high-affinity arginine transmembrane transporter activity(GO:0005289) high-affinity lysine transmembrane transporter activity(GO:0005292)
0.0 0.2 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.1 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.0 0.1 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.0 0.3 GO:0031386 protein tag(GO:0031386)
0.0 0.1 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.0 0.1 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.0 0.1 GO:0035500 MH2 domain binding(GO:0035500)
0.0 0.1 GO:1904713 beta-catenin destruction complex binding(GO:1904713)
0.0 0.1 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.5 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.1 GO:0015633 zinc transporting ATPase activity(GO:0015633)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.1 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.0 0.2 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.0 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.0 0.0 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.4 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.0 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.0 0.2 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.0 GO:0030984 kininogen binding(GO:0030984)
0.0 0.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.3 GO:0005537 mannose binding(GO:0005537)
0.0 0.1 GO:0070051 fibrinogen binding(GO:0070051)
0.0 0.2 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.0 GO:0009383 rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383)
0.0 0.2 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.1 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.0 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.0 0.1 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.0 GO:0032093 SAM domain binding(GO:0032093)
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.0 GO:0031177 phosphopantetheine binding(GO:0031177)
0.0 0.2 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.0 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.0 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.0 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
0.0 0.1 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.0 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.0 0.2 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.0 GO:0003878 ATP citrate synthase activity(GO:0003878)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.5 PID AURORA B PATHWAY Aurora B signaling
0.0 0.0 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.1 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.3 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.5 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.3 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.1 REACTOME CELL CYCLE Genes involved in Cell Cycle
0.0 0.1 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.1 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins