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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for MSX2

Z-value: 0.38

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Transcription factors associated with MSX2

Gene Symbol Gene ID Gene Info
ENSG00000120149.7 msh homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MSX2hg19_v2_chr5_+_174151536_174151610-0.534.7e-01Click!

Activity profile of MSX2 motif

Sorted Z-values of MSX2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_9102632 0.22 ENST00000539240.1
killer cell lectin-like receptor subfamily G, member 1
chr12_-_9102224 0.21 ENST00000543845.1
ENST00000544245.1
mannose-6-phosphate receptor (cation dependent)
chr5_-_31532238 0.16 ENST00000507438.1
drosha, ribonuclease type III
chr7_-_100183742 0.15 ENST00000310300.6
leucine-rich repeats and calponin homology (CH) domain containing 4
chr14_-_88200641 0.14 ENST00000556168.1
RP11-1152H15.1
chr16_+_53133070 0.13 ENST00000565832.1
chromodomain helicase DNA binding protein 9
chr22_+_46476192 0.12 ENST00000443490.1
hsa-mir-4763
chr20_-_50418947 0.11 ENST00000371539.3
spalt-like transcription factor 4
chr11_+_17298342 0.10 ENST00000530964.1
nucleobindin 2
chr8_-_1922789 0.10 ENST00000521498.1
RP11-439C15.4
chr1_+_27158505 0.09 ENST00000534643.1
zinc finger, DHHC-type containing 18
chr1_-_158173659 0.09 ENST00000415019.1
RP11-404O13.5
chr12_-_10022735 0.09 ENST00000228438.2
C-type lectin domain family 2, member B
chr11_+_101918153 0.09 ENST00000434758.2
ENST00000526781.1
ENST00000534360.1
chromosome 11 open reading frame 70
chr3_-_120400960 0.09 ENST00000476082.2
homogentisate 1,2-dioxygenase
chr14_-_51027838 0.08 ENST00000555216.1
mitogen-activated protein kinase kinase kinase kinase 5
chr10_+_85954377 0.08 ENST00000332904.3
ENST00000372117.3
cadherin-related family member 1
chr20_-_50418972 0.08 ENST00000395997.3
spalt-like transcription factor 4
chr1_+_11714914 0.08 ENST00000425796.1
ENST00000376770.1
ENST00000376768.1
ENST00000251547.5
ENST00000376760.1
ENST00000376762.4
F-box protein 44
chr19_+_11485333 0.07 ENST00000312423.2
SWIM-type zinc finger 7 associated protein 1
chrX_+_70752945 0.06 ENST00000373701.3
O-linked N-acetylglucosamine (GlcNAc) transferase
chr3_-_112127981 0.06 ENST00000486726.2
RP11-231E6.1
chr7_+_130794878 0.06 ENST00000416992.2
muskelin 1, intracellular mediator containing kelch motifs
chr16_-_29934558 0.06 ENST00000568995.1
ENST00000566413.1
potassium channel tetramerization domain containing 13
chr6_-_111927062 0.05 ENST00000359831.4
TRAF3 interacting protein 2
chr20_-_50419055 0.05 ENST00000217086.4
spalt-like transcription factor 4
chr19_+_42817450 0.05 ENST00000301204.3
transmembrane protein 145
chr12_+_28410128 0.05 ENST00000381259.1
ENST00000381256.1
coiled-coil domain containing 91
chr5_+_66254698 0.05 ENST00000405643.1
ENST00000407621.1
ENST00000432426.1
microtubule associated serine/threonine kinase family member 4
chr1_+_81001398 0.05 ENST00000418041.1
ENST00000443104.1
RP5-887A10.1
chr1_-_36916066 0.04 ENST00000315643.9
organic solute carrier partner 1
chr15_-_98417780 0.04 ENST00000503874.3
long intergenic non-protein coding RNA 923
chr3_-_141747950 0.04 ENST00000497579.1
transcription factor Dp-2 (E2F dimerization partner 2)
chr7_+_130794846 0.04 ENST00000421797.2
muskelin 1, intracellular mediator containing kelch motifs
chr17_-_12920907 0.04 ENST00000609757.1
ENST00000581499.2
ENST00000580504.1
elaC ribonuclease Z 2
chr7_+_91570165 0.04 ENST00000356239.3
ENST00000359028.2
ENST00000358100.2
A kinase (PRKA) anchor protein 9
chr4_-_171012844 0.04 ENST00000502392.1
aminoadipate aminotransferase
chr9_+_80912059 0.04 ENST00000347159.2
ENST00000376588.3
phosphoserine aminotransferase 1
chr11_+_17298522 0.04 ENST00000529313.1
nucleobindin 2
chr2_-_27603582 0.04 ENST00000323703.6
ENST00000436006.1
zinc finger protein 513
chr3_+_186353756 0.03 ENST00000431018.1
ENST00000450521.1
ENST00000539949.1
fetuin B
chr7_+_99717230 0.03 ENST00000262932.3
canopy FGF signaling regulator 4
chr9_-_5339873 0.03 ENST00000223862.1
ENST00000223858.4
relaxin 1
chr16_+_69345243 0.03 ENST00000254950.11
vacuolar protein sorting 4 homolog A (S. cerevisiae)
chr12_-_95397442 0.03 ENST00000547157.1
ENST00000547986.1
ENST00000327772.2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12
chr8_-_117886563 0.03 ENST00000519837.1
ENST00000522699.1
RAD21 homolog (S. pombe)
chr5_-_148758839 0.03 ENST00000261796.3
interleukin 17B
chr1_-_197115818 0.03 ENST00000367409.4
ENST00000294732.7
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
chr7_-_99716940 0.03 ENST00000440225.1
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr8_+_9413410 0.03 ENST00000520408.1
ENST00000310430.6
ENST00000522110.1
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr1_+_211813019 0.03 ENST00000430123.1
RP11-354K1.1
chr1_-_21625486 0.03 ENST00000481130.2
endothelin converting enzyme 1
chrX_+_70752917 0.03 ENST00000373719.3
O-linked N-acetylglucosamine (GlcNAc) transferase
chr1_+_202317815 0.03 ENST00000608999.1
ENST00000336894.4
ENST00000480184.1
protein phosphatase 1, regulatory subunit 12B
chr1_-_23694794 0.02 ENST00000374608.3
zinc finger protein 436
chr22_+_17956618 0.02 ENST00000262608.8
cat eye syndrome chromosome region, candidate 2
chr19_+_46236509 0.02 ENST00000457052.2
Uncharacterized protein
chr20_+_49126881 0.02 ENST00000371621.3
ENST00000541713.1
protein tyrosine phosphatase, non-receptor type 1
chr17_+_67759813 0.02 ENST00000587241.1
AC003051.1
chr20_+_56964253 0.02 ENST00000395802.3
VAMP (vesicle-associated membrane protein)-associated protein B and C
chrX_-_48931648 0.02 ENST00000376386.3
ENST00000376390.4
PRA1 domain family, member 2
chr5_+_150639360 0.02 ENST00000523004.1
GM2 ganglioside activator
chr7_+_100210133 0.02 ENST00000393950.2
ENST00000424091.2
motile sperm domain containing 3
chr3_-_11685345 0.02 ENST00000430365.2
vestigial like 4 (Drosophila)
chr17_+_44679808 0.02 ENST00000571172.1
N-ethylmaleimide-sensitive factor
chr12_+_64798826 0.02 ENST00000540203.1
exportin, tRNA
chr1_-_151965048 0.02 ENST00000368809.1
S100 calcium binding protein A10
chr15_-_37393406 0.02 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
Meis homeobox 2
chr5_+_140557371 0.02 ENST00000239444.2
protocadherin beta 8
chr9_+_124329336 0.02 ENST00000394340.3
ENST00000436835.1
ENST00000259371.2
DAB2 interacting protein
chr14_+_65381079 0.02 ENST00000549115.1
ENST00000607599.1
ENST00000548752.2
ENST00000359118.2
ENST00000552002.2
ENST00000551947.1
ENST00000551093.1
ENST00000542227.1
ENST00000447296.2
ENST00000549987.1
churchill domain containing 1
farnesyltransferase, CAAX box, beta
CHURC1-FNTB readthrough
chr11_+_108535849 0.02 ENST00000526794.1
DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
chr17_+_74261277 0.02 ENST00000327490.6
UBA-like domain containing 2
chr8_-_12612962 0.02 ENST00000398246.3
LON peptidase N-terminal domain and ring finger 1
chr19_-_10121144 0.02 ENST00000264828.3
collagen, type V, alpha 3
chr5_-_31532160 0.02 ENST00000511367.2
ENST00000513349.1
drosha, ribonuclease type III
chr10_-_105110831 0.02 ENST00000337211.4
polycomb group ring finger 6
chr8_+_38831683 0.02 ENST00000302495.4
HtrA serine peptidase 4
chr6_-_111927449 0.02 ENST00000368761.5
ENST00000392556.4
ENST00000340026.6
TRAF3 interacting protein 2
chr11_+_17298297 0.02 ENST00000529010.1
nucleobindin 2
chr7_+_100209725 0.02 ENST00000223054.4
motile sperm domain containing 3
chr10_-_56561022 0.01 ENST00000373965.2
ENST00000414778.1
ENST00000395438.1
ENST00000409834.1
ENST00000395445.1
ENST00000395446.1
ENST00000395442.1
ENST00000395440.1
ENST00000395432.2
ENST00000361849.3
ENST00000395433.1
ENST00000320301.6
ENST00000395430.1
ENST00000437009.1
protocadherin-related 15
chr19_+_41869894 0.01 ENST00000413014.2
transmembrane protein 91
chr21_-_22175341 0.01 ENST00000416768.1
ENST00000452561.1
ENST00000419299.1
ENST00000437238.1
long intergenic non-protein coding RNA 320
chr14_+_32798462 0.01 ENST00000280979.4
A kinase (PRKA) anchor protein 6
chr14_-_23504432 0.01 ENST00000425762.2
proteasome (prosome, macropain) subunit, beta type, 5
chr1_+_44115814 0.01 ENST00000372396.3
lysine (K)-specific demethylase 4A
chr17_-_38956205 0.01 ENST00000306658.7
keratin 28
chr17_-_43045439 0.01 ENST00000253407.3
complement component 1, q subcomponent-like 1
chr1_-_36916011 0.01 ENST00000356637.5
ENST00000354267.3
ENST00000235532.5
organic solute carrier partner 1
chr6_+_25652432 0.01 ENST00000377961.2
secretagogin, EF-hand calcium binding protein
chr1_-_8877692 0.01 ENST00000400908.2
arginine-glutamic acid dipeptide (RE) repeats
chr3_-_151034734 0.01 ENST00000260843.4
G protein-coupled receptor 87
chr20_-_54967187 0.01 ENST00000422322.1
ENST00000371356.2
ENST00000451915.1
ENST00000347343.2
ENST00000395911.1
ENST00000395907.1
ENST00000441357.1
ENST00000456249.1
ENST00000420474.1
ENST00000395909.4
ENST00000395914.1
ENST00000312783.6
ENST00000395915.3
ENST00000395913.3
aurora kinase A
chr7_-_99716952 0.01 ENST00000523306.1
ENST00000344095.4
ENST00000417349.1
ENST00000493322.1
ENST00000520135.1
ENST00000418432.2
ENST00000460673.2
ENST00000452041.1
ENST00000452438.2
ENST00000451699.1
ENST00000453269.2
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr6_+_34204642 0.01 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
high mobility group AT-hook 1
chr1_-_68698222 0.01 ENST00000370976.3
ENST00000354777.2
ENST00000262348.4
ENST00000540432.1
wntless Wnt ligand secretion mediator
chr22_-_30960876 0.01 ENST00000401975.1
ENST00000428682.1
ENST00000423299.1
galactose-3-O-sulfotransferase 1
chr8_-_117886612 0.01 ENST00000520992.1
RAD21 homolog (S. pombe)
chr7_+_134331550 0.01 ENST00000344924.3
ENST00000418040.1
ENST00000393132.2
2,3-bisphosphoglycerate mutase
chr19_+_4007644 0.01 ENST00000262971.2
protein inhibitor of activated STAT, 4
chr5_+_140797296 0.01 ENST00000398594.2
protocadherin gamma subfamily B, 7
chr2_+_187371440 0.01 ENST00000445547.1
zinc finger CCCH-type containing 15
chr7_-_56174161 0.01 ENST00000395422.3
coiled-coil-helix-coiled-coil-helix domain containing 2
chr12_-_9102549 0.01 ENST00000000412.3
mannose-6-phosphate receptor (cation dependent)
chr17_+_12569306 0.01 ENST00000425538.1
myocardin
chr12_-_120315074 0.01 ENST00000261833.7
ENST00000392521.2
citron (rho-interacting, serine/threonine kinase 21)
chr11_+_33061543 0.00 ENST00000432887.1
ENST00000528898.1
ENST00000531632.2
t-complex 11, testis-specific-like 1
chr6_-_167040731 0.00 ENST00000265678.4
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr2_-_73460334 0.00 ENST00000258083.2
protease-associated domain containing 1
chr9_+_34646624 0.00 ENST00000450095.2
ENST00000556278.1
galactose-1-phosphate uridylyltransferase
Uncharacterized protein
chr17_-_38574169 0.00 ENST00000423485.1
topoisomerase (DNA) II alpha 170kDa
chr4_-_69434245 0.00 ENST00000317746.2
UDP glucuronosyltransferase 2 family, polypeptide B17
chr11_-_102323740 0.00 ENST00000398136.2
transmembrane protein 123
chr3_-_114866084 0.00 ENST00000357258.3
zinc finger and BTB domain containing 20
chr4_-_109684120 0.00 ENST00000512646.1
ENST00000411864.2
ENST00000296486.3
ENST00000510706.1
ethanolamine-phosphate phospho-lyase
chr5_+_95997885 0.00 ENST00000511097.2
calpastatin
chr5_+_162864575 0.00 ENST00000512163.1
ENST00000393929.1
ENST00000340828.2
ENST00000511683.2
ENST00000510097.1
ENST00000511490.2
ENST00000510664.1
cyclin G1
chr2_-_98280383 0.00 ENST00000289228.5
ARP1 actin-related protein 1 homolog B, centractin beta (yeast)
chr13_-_103389159 0.00 ENST00000322527.2
coiled-coil domain containing 168
chr14_-_23504337 0.00 ENST00000361611.6
proteasome (prosome, macropain) subunit, beta type, 5
chr1_-_151431674 0.00 ENST00000531094.1
pogo transposable element with ZNF domain
chr17_+_42264556 0.00 ENST00000319511.6
ENST00000589785.1
ENST00000592825.1
ENST00000589184.1
transmembrane and ubiquitin-like domain containing 2

Network of associatons between targets according to the STRING database.

First level regulatory network of MSX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0 0.2 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.0 0.0 GO:0072684 mitochondrial tRNA 3'-trailer cleavage, endonucleolytic(GO:0072684)
0.0 0.2 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.2 GO:2000628 production of siRNA involved in RNA interference(GO:0030422) regulation of miRNA metabolic process(GO:2000628)
0.0 0.0 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0070877 microprocessor complex(GO:0070877) ribonuclease III complex(GO:1903095)
0.0 0.1 GO:0097196 Shu complex(GO:0097196)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0 0.1 GO:0097363 protein O-GlcNAc transferase activity(GO:0097363)
0.0 0.0 GO:0047536 2-aminoadipate transaminase activity(GO:0047536)
0.0 0.2 GO:0005537 mannose binding(GO:0005537)
0.0 0.0 GO:0042781 3'-tRNA processing endoribonuclease activity(GO:0042781)