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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)
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Results for MYB
Z-value: 3.43
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Transcription factors associated with MYB
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| MYB | hg19_v2_chr6_+_135502466_135502489 | 0.87 | 1.3e-01 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of MYB
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.7 | GO:0045737 | positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) |
| 0.1 | 3.3 | GO:0061003 | positive regulation of dendritic spine morphogenesis(GO:0061003) |
| 0.0 | 3.2 | GO:0035335 | peptidyl-tyrosine dephosphorylation(GO:0035335) |
| 0.1 | 3.1 | GO:0016180 | snRNA processing(GO:0016180) |
| 0.1 | 3.1 | GO:0035036 | sperm-egg recognition(GO:0035036) |
| 0.1 | 3.0 | GO:0035020 | regulation of Rac protein signal transduction(GO:0035020) |
| 0.4 | 2.8 | GO:1903026 | negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026) |
| 0.1 | 2.5 | GO:2000574 | regulation of microtubule motor activity(GO:2000574) |
| 0.0 | 2.1 | GO:0090307 | mitotic spindle assembly(GO:0090307) |
| 0.1 | 2.0 | GO:0070389 | chaperone cofactor-dependent protein refolding(GO:0070389) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 6.7 | GO:0034451 | centriolar satellite(GO:0034451) |
| 0.1 | 4.7 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 0.2 | 3.1 | GO:0032039 | integrator complex(GO:0032039) |
| 0.0 | 2.8 | GO:0000776 | kinetochore(GO:0000776) |
| 0.0 | 2.7 | GO:0031514 | motile cilium(GO:0031514) |
| 0.8 | 2.3 | GO:1990622 | CHOP-ATF3 complex(GO:1990622) |
| 0.0 | 2.3 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
| 0.1 | 2.2 | GO:0070822 | Sin3-type complex(GO:0070822) |
| 0.1 | 2.0 | GO:0071782 | endoplasmic reticulum tubular network(GO:0071782) |
| 0.0 | 2.0 | GO:0097546 | ciliary base(GO:0097546) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 4.5 | GO:0001671 | ATPase activator activity(GO:0001671) |
| 0.1 | 3.7 | GO:0008143 | poly(A) binding(GO:0008143) |
| 0.0 | 3.3 | GO:0008017 | microtubule binding(GO:0008017) |
| 0.0 | 2.7 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
| 0.0 | 2.3 | GO:0019003 | GDP binding(GO:0019003) |
| 0.1 | 2.2 | GO:0051959 | dynein light intermediate chain binding(GO:0051959) |
| 0.1 | 2.0 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
| 0.1 | 2.0 | GO:0009982 | pseudouridine synthase activity(GO:0009982) |
| 0.3 | 1.9 | GO:0061575 | cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575) |
| 0.0 | 1.8 | GO:0008536 | Ran GTPase binding(GO:0008536) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 3.9 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.0 | 3.0 | PID TELOMERASE PATHWAY | Regulation of Telomerase |
| 0.0 | 2.9 | PID FOXM1 PATHWAY | FOXM1 transcription factor network |
| 0.0 | 2.9 | PID P38 ALPHA BETA DOWNSTREAM PATHWAY | Signaling mediated by p38-alpha and p38-beta |
| 0.0 | 2.5 | PID LIS1 PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 0.0 | 2.2 | PID MTOR 4PATHWAY | mTOR signaling pathway |
| 0.0 | 1.8 | PID ARF6 TRAFFICKING PATHWAY | Arf6 trafficking events |
| 0.0 | 1.7 | PID RB 1PATHWAY | Regulation of retinoblastoma protein |
| 0.0 | 1.2 | PID TCR CALCIUM PATHWAY | Calcium signaling in the CD4+ TCR pathway |
| 0.0 | 1.2 | PID ATM PATHWAY | ATM pathway |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 5.6 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.0 | 5.1 | REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
| 0.0 | 3.5 | REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE | Genes involved in SRP-dependent cotranslational protein targeting to membrane |
| 0.1 | 2.9 | REACTOME PROCESSING OF INTRONLESS PRE MRNAS | Genes involved in Processing of Intronless Pre-mRNAs |
| 0.2 | 2.4 | REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA | Genes involved in Activation of Chaperone Genes by ATF6-alpha |
| 0.1 | 2.2 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 0.1 | 1.9 | REACTOME MTORC1 MEDIATED SIGNALLING | Genes involved in mTORC1-mediated signalling |
| 0.0 | 1.9 | REACTOME G1 PHASE | Genes involved in G1 Phase |
| 0.1 | 1.7 | REACTOME PLATELET CALCIUM HOMEOSTASIS | Genes involved in Platelet calcium homeostasis |
| 0.0 | 1.7 | REACTOME MEIOSIS | Genes involved in Meiosis |