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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for NFKB1

Z-value: 0.72

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Transcription factors associated with NFKB1

Gene Symbol Gene ID Gene Info
NFKB1
ENSG00000109320.7 nuclear factor kappa B subunit 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFKB1hg19_v2_chr4_+_103422499_1034226320.851.5e-01Click!

Activity profile of NFKB1 motif

Sorted Z-values of NFKB1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_39735646 0.62 ENST00000413851.2
IFNL3
interferon, lambda 3
chr19_+_39759154 0.53 ENST00000331982.5
IFNL2
interferon, lambda 2
chr6_+_138188351 0.50 ENST00000421450.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr1_+_6845578 0.43 ENST00000467404.2
ENST00000439411.2
CAMTA1
calmodulin binding transcription activator 1
chr4_-_74904398 0.41 ENST00000296026.4
CXCL3
chemokine (C-X-C motif) ligand 3
chr2_-_61108449 0.40 ENST00000439412.1
ENST00000452343.1
AC010733.4
AC010733.4
chr4_+_103422499 0.36 ENST00000511926.1
ENST00000507079.1
NFKB1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr4_+_74735102 0.35 ENST00000395761.3
CXCL1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr6_-_31550192 0.34 ENST00000429299.2
ENST00000446745.2
LTB
lymphotoxin beta (TNF superfamily, member 3)
chr12_-_49259643 0.30 ENST00000309739.5
RND1
Rho family GTPase 1
chr9_+_82188077 0.30 ENST00000425506.1
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr1_+_6845497 0.28 ENST00000473578.1
ENST00000557126.1
CAMTA1
calmodulin binding transcription activator 1
chr17_-_77179487 0.27 ENST00000580508.1
RBFOX3
RNA binding protein, fox-1 homolog (C. elegans) 3
chr2_+_228678550 0.26 ENST00000409189.3
ENST00000358813.4
CCL20
chemokine (C-C motif) ligand 20
chr17_-_61776522 0.25 ENST00000582055.1
LIMD2
LIM domain containing 2
chr7_+_143013198 0.24 ENST00000343257.2
CLCN1
chloride channel, voltage-sensitive 1
chr16_-_66959429 0.24 ENST00000420652.1
ENST00000299759.6
RRAD
Ras-related associated with diabetes
chr11_+_94706804 0.23 ENST00000335080.5
KDM4D
lysine (K)-specific demethylase 4D
chr15_-_89438742 0.23 ENST00000562281.1
ENST00000562889.1
ENST00000359595.3
HAPLN3
hyaluronan and proteoglycan link protein 3
chr10_+_12391685 0.22 ENST00000378845.1
CAMK1D
calcium/calmodulin-dependent protein kinase ID
chr6_+_138188551 0.20 ENST00000237289.4
ENST00000433680.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr19_+_39574945 0.19 ENST00000331256.5
PAPL
Iron/zinc purple acid phosphatase-like protein
chr20_+_6748311 0.19 ENST00000378827.4
BMP2
bone morphogenetic protein 2
chr6_+_144471643 0.19 ENST00000367568.4
STX11
syntaxin 11
chr2_-_211036051 0.19 ENST00000418791.1
ENST00000452086.1
ENST00000281772.9
KANSL1L
KAT8 regulatory NSL complex subunit 1-like
chr14_-_51297360 0.18 ENST00000496749.1
NIN
ninein (GSK3B interacting protein)
chr1_+_56880606 0.18 ENST00000451914.1
RP4-710M16.2
RP4-710M16.2
chr12_-_12849073 0.18 ENST00000332427.2
ENST00000540796.1
GPR19
G protein-coupled receptor 19
chr4_-_5891918 0.18 ENST00000512574.1
CRMP1
collapsin response mediator protein 1
chr2_+_176957619 0.17 ENST00000392539.3
HOXD13
homeobox D13
chr12_+_52445191 0.17 ENST00000243050.1
ENST00000394825.1
ENST00000550763.1
ENST00000394824.2
ENST00000548232.1
ENST00000562373.1
NR4A1
nuclear receptor subfamily 4, group A, member 1
chr16_+_29823427 0.17 ENST00000358758.7
ENST00000567659.1
ENST00000572820.1
PRRT2
proline-rich transmembrane protein 2
chr2_+_29001711 0.17 ENST00000418910.1
PPP1CB
protein phosphatase 1, catalytic subunit, beta isozyme
chr1_-_38100539 0.17 ENST00000401069.1
RSPO1
R-spondin 1
chr12_+_7053228 0.17 ENST00000540506.2
C12orf57
chromosome 12 open reading frame 57
chr14_-_35873856 0.17 ENST00000553342.1
ENST00000216797.5
ENST00000557140.1
NFKBIA
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
chr2_+_112895939 0.17 ENST00000331203.2
ENST00000409903.1
ENST00000409667.3
ENST00000409450.3
FBLN7
fibulin 7
chr5_+_170846640 0.17 ENST00000274625.5
FGF18
fibroblast growth factor 18
chr1_-_8000872 0.16 ENST00000377507.3
TNFRSF9
tumor necrosis factor receptor superfamily, member 9
chr6_-_29527702 0.16 ENST00000377050.4
UBD
ubiquitin D
chr20_-_44937124 0.16 ENST00000537909.1
CDH22
cadherin 22, type 2
chr14_+_96343100 0.16 ENST00000503525.2
LINC00617
long intergenic non-protein coding RNA 617
chr4_-_74964904 0.15 ENST00000508487.2
CXCL2
chemokine (C-X-C motif) ligand 2
chr17_+_46189311 0.15 ENST00000582481.1
SNX11
sorting nexin 11
chr20_+_44746939 0.15 ENST00000372276.3
CD40
CD40 molecule, TNF receptor superfamily member 5
chr9_-_140115775 0.15 ENST00000391553.1
ENST00000392827.1
RNF208
ring finger protein 208
chr2_-_42721110 0.15 ENST00000394973.4
ENST00000306078.1
KCNG3
potassium voltage-gated channel, subfamily G, member 3
chr8_-_103668114 0.15 ENST00000285407.6
KLF10
Kruppel-like factor 10
chr20_-_62103862 0.15 ENST00000344462.4
ENST00000357249.2
ENST00000359125.2
ENST00000360480.3
ENST00000370224.1
ENST00000344425.5
ENST00000354587.3
ENST00000359689.1
KCNQ2
potassium voltage-gated channel, KQT-like subfamily, member 2
chr6_+_138188378 0.15 ENST00000420009.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr6_-_35464727 0.14 ENST00000402886.3
TEAD3
TEA domain family member 3
chr1_-_161168834 0.14 ENST00000367995.3
ENST00000367996.5
ADAMTS4
ADAM metallopeptidase with thrombospondin type 1 motif, 4
chr7_-_56101826 0.14 ENST00000421626.1
PSPH
phosphoserine phosphatase
chr3_-_111852061 0.14 ENST00000488580.1
ENST00000460387.2
ENST00000484193.1
ENST00000487901.1
GCSAM
germinal center-associated, signaling and motility
chr4_-_147442982 0.14 ENST00000511374.1
ENST00000264986.3
SLC10A7
solute carrier family 10, member 7
chr14_+_96342729 0.14 ENST00000504119.1
LINC00617
long intergenic non-protein coding RNA 617
chr19_+_2476116 0.14 ENST00000215631.4
ENST00000587345.1
GADD45B
growth arrest and DNA-damage-inducible, beta
chr20_-_42816206 0.14 ENST00000372980.3
JPH2
junctophilin 2
chr1_+_100818156 0.13 ENST00000336454.3
CDC14A
cell division cycle 14A
chr11_+_94706973 0.13 ENST00000536741.1
KDM4D
lysine (K)-specific demethylase 4D
chr1_+_26872324 0.13 ENST00000531382.1
RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr12_-_62997214 0.13 ENST00000408887.2
C12orf61
chromosome 12 open reading frame 61
chr12_-_58131931 0.13 ENST00000547588.1
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr2_-_157189180 0.12 ENST00000539077.1
ENST00000424077.1
ENST00000426264.1
ENST00000339562.4
ENST00000421709.1
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr10_+_99609996 0.12 ENST00000370602.1
GOLGA7B
golgin A7 family, member B
chr17_+_21191341 0.12 ENST00000526076.2
ENST00000361818.5
ENST00000316920.6
MAP2K3
mitogen-activated protein kinase kinase 3
chr14_+_32798547 0.12 ENST00000557354.1
ENST00000557102.1
ENST00000557272.1
AKAP6
A kinase (PRKA) anchor protein 6
chr13_+_108921977 0.12 ENST00000430559.1
ENST00000375887.4
TNFSF13B
tumor necrosis factor (ligand) superfamily, member 13b
chr2_-_193059250 0.12 ENST00000409056.3
TMEFF2
transmembrane protein with EGF-like and two follistatin-like domains 2
chr4_-_74864386 0.12 ENST00000296027.4
CXCL5
chemokine (C-X-C motif) ligand 5
chr12_+_7053172 0.12 ENST00000229281.5
C12orf57
chromosome 12 open reading frame 57
chr10_+_104154229 0.12 ENST00000428099.1
ENST00000369966.3
NFKB2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr6_-_24720226 0.12 ENST00000378102.3
C6orf62
chromosome 6 open reading frame 62
chr17_+_4854375 0.12 ENST00000521811.1
ENST00000519602.1
ENST00000323997.6
ENST00000522249.1
ENST00000519584.1
ENO3
enolase 3 (beta, muscle)
chr8_+_26149007 0.11 ENST00000380737.3
ENST00000524169.1
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr15_+_33010175 0.11 ENST00000300177.4
ENST00000560677.1
ENST00000560830.1
GREM1
gremlin 1, DAN family BMP antagonist
chr19_+_45504688 0.11 ENST00000221452.8
ENST00000540120.1
ENST00000505236.1
RELB
v-rel avian reticuloendotheliosis viral oncogene homolog B
chr1_-_155658085 0.11 ENST00000311573.5
ENST00000438245.2
YY1AP1
YY1 associated protein 1
chr19_+_10527449 0.11 ENST00000592685.1
ENST00000380702.2
PDE4A
phosphodiesterase 4A, cAMP-specific
chr7_+_120969045 0.11 ENST00000222462.2
WNT16
wingless-type MMTV integration site family, member 16
chr4_-_147443043 0.11 ENST00000394059.4
ENST00000502607.1
ENST00000335472.7
ENST00000432059.2
ENST00000394062.3
SLC10A7
solute carrier family 10, member 7
chr17_-_56065540 0.10 ENST00000583932.1
VEZF1
vascular endothelial zinc finger 1
chr16_-_28222797 0.10 ENST00000569951.1
ENST00000565698.1
XPO6
exportin 6
chr10_-_6104253 0.10 ENST00000256876.6
ENST00000379954.1
ENST00000379959.3
IL2RA
interleukin 2 receptor, alpha
chr6_-_44233361 0.10 ENST00000275015.5
NFKBIE
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
chr6_-_35464817 0.10 ENST00000338863.7
TEAD3
TEA domain family member 3
chr16_-_77468945 0.10 ENST00000282849.5
ADAMTS18
ADAM metallopeptidase with thrombospondin type 1 motif, 18
chr2_+_64681641 0.10 ENST00000409537.2
LGALSL
lectin, galactoside-binding-like
chr12_-_102455846 0.10 ENST00000545679.1
CCDC53
coiled-coil domain containing 53
chr7_-_93520191 0.10 ENST00000545378.1
TFPI2
tissue factor pathway inhibitor 2
chr12_+_100661156 0.09 ENST00000360820.2
SCYL2
SCY1-like 2 (S. cerevisiae)
chr11_+_102188272 0.09 ENST00000532808.1
BIRC3
baculoviral IAP repeat containing 3
chr20_+_18488528 0.09 ENST00000377465.1
SEC23B
Sec23 homolog B (S. cerevisiae)
chr11_+_102188224 0.09 ENST00000263464.3
BIRC3
baculoviral IAP repeat containing 3
chrX_-_38080077 0.09 ENST00000378533.3
ENST00000544439.1
ENST00000432886.2
ENST00000538295.1
SRPX
sushi-repeat containing protein, X-linked
chr20_+_18488137 0.09 ENST00000450074.1
ENST00000262544.2
ENST00000336714.3
ENST00000377475.3
SEC23B
Sec23 homolog B (S. cerevisiae)
chr19_-_51920952 0.09 ENST00000356298.5
ENST00000339313.5
ENST00000529627.1
ENST00000439889.2
ENST00000353836.5
ENST00000432469.2
SIGLEC10
sialic acid binding Ig-like lectin 10
chr4_-_185395672 0.09 ENST00000393593.3
IRF2
interferon regulatory factor 2
chr15_+_89346699 0.09 ENST00000558207.1
ACAN
aggrecan
chr5_-_55290773 0.09 ENST00000502326.3
ENST00000381298.2
IL6ST
interleukin 6 signal transducer (gp130, oncostatin M receptor)
chr19_+_17638041 0.09 ENST00000601861.1
FAM129C
family with sequence similarity 129, member C
chr19_-_39390350 0.09 ENST00000447739.1
ENST00000358931.5
ENST00000407552.1
SIRT2
sirtuin 2
chr3_+_159557637 0.09 ENST00000445224.2
SCHIP1
schwannomin interacting protein 1
chr4_-_5890145 0.09 ENST00000397890.2
CRMP1
collapsin response mediator protein 1
chr19_-_39390440 0.09 ENST00000249396.7
ENST00000414941.1
ENST00000392081.2
SIRT2
sirtuin 2
chr17_-_75878647 0.09 ENST00000374983.2
FLJ45079
FLJ45079
chr6_-_31138439 0.09 ENST00000259915.8
POU5F1
POU class 5 homeobox 1
chr6_-_30523865 0.09 ENST00000433809.1
GNL1
guanine nucleotide binding protein-like 1
chr16_+_67465016 0.09 ENST00000326152.5
HSD11B2
hydroxysteroid (11-beta) dehydrogenase 2
chr11_-_77185094 0.09 ENST00000278568.4
ENST00000356341.3
PAK1
p21 protein (Cdc42/Rac)-activated kinase 1
chr19_+_42364460 0.08 ENST00000593863.1
RPS19
ribosomal protein S19
chr12_-_57081940 0.08 ENST00000436399.2
PTGES3
prostaglandin E synthase 3 (cytosolic)
chr3_+_10857885 0.08 ENST00000254488.2
ENST00000454147.1
SLC6A11
solute carrier family 6 (neurotransmitter transporter), member 11
chr1_-_236030216 0.08 ENST00000389794.3
ENST00000389793.2
LYST
lysosomal trafficking regulator
chr1_-_186649543 0.08 ENST00000367468.5
PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr7_-_93520259 0.08 ENST00000222543.5
TFPI2
tissue factor pathway inhibitor 2
chr2_+_163175394 0.08 ENST00000446271.1
ENST00000429691.2
GCA
grancalcin, EF-hand calcium binding protein
chr1_-_204436344 0.08 ENST00000367184.2
PIK3C2B
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
chr1_-_36615065 0.08 ENST00000373166.3
ENST00000373159.1
ENST00000373162.1
TRAPPC3
trafficking protein particle complex 3
chr16_-_28223166 0.08 ENST00000304658.5
XPO6
exportin 6
chr15_-_66545995 0.08 ENST00000395614.1
ENST00000288745.3
ENST00000422354.1
ENST00000395625.2
ENST00000360698.4
ENST00000409699.2
MEGF11
multiple EGF-like-domains 11
chr19_+_55795493 0.08 ENST00000309383.1
BRSK1
BR serine/threonine kinase 1
chrX_-_37706815 0.08 ENST00000378578.4
DYNLT3
dynein, light chain, Tctex-type 3
chr1_-_32403903 0.08 ENST00000344035.6
ENST00000356536.3
PTP4A2
protein tyrosine phosphatase type IVA, member 2
chr9_-_115480303 0.08 ENST00000374234.1
ENST00000374238.1
ENST00000374236.1
ENST00000374242.4
INIP
INTS3 and NABP interacting protein
chr1_+_159796534 0.08 ENST00000289707.5
SLAMF8
SLAM family member 8
chr20_+_44746885 0.08 ENST00000372285.3
CD40
CD40 molecule, TNF receptor superfamily member 5
chr11_-_46142615 0.08 ENST00000529734.1
ENST00000323180.6
PHF21A
PHD finger protein 21A
chrX_-_73072534 0.08 ENST00000429829.1
XIST
X inactive specific transcript (non-protein coding)
chr3_-_111852128 0.08 ENST00000308910.4
GCSAM
germinal center-associated, signaling and motility
chr14_-_61190754 0.07 ENST00000216513.4
SIX4
SIX homeobox 4
chr10_-_97050777 0.07 ENST00000329399.6
PDLIM1
PDZ and LIM domain 1
chr6_+_14117872 0.07 ENST00000379153.3
CD83
CD83 molecule
chr3_-_4793274 0.07 ENST00000414938.1
EGOT
eosinophil granule ontogeny transcript (non-protein coding)
chr10_+_13142075 0.07 ENST00000378757.2
ENST00000430081.1
ENST00000378752.3
ENST00000378748.3
OPTN
optineurin
chr5_-_150460914 0.07 ENST00000389378.2
TNIP1
TNFAIP3 interacting protein 1
chr4_+_103422471 0.07 ENST00000226574.4
ENST00000394820.4
NFKB1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr10_-_13390021 0.07 ENST00000537130.1
SEPHS1
selenophosphate synthetase 1
chr15_-_66084621 0.07 ENST00000564674.1
DENND4A
DENN/MADD domain containing 4A
chr19_-_51920835 0.07 ENST00000442846.3
ENST00000530476.1
SIGLEC10
sialic acid binding Ig-like lectin 10
chr14_+_24521202 0.07 ENST00000334420.7
ENST00000342740.5
LRRC16B
leucine rich repeat containing 16B
chr17_-_61819229 0.07 ENST00000447001.3
ENST00000392950.4
STRADA
STE20-related kinase adaptor alpha
chr9_-_127952187 0.07 ENST00000451402.1
ENST00000415905.1
PPP6C
protein phosphatase 6, catalytic subunit
chr6_-_30080863 0.07 ENST00000540829.1
TRIM31
tripartite motif containing 31
chr10_+_13141585 0.07 ENST00000378764.2
OPTN
optineurin
chr19_+_17638059 0.06 ENST00000599164.1
ENST00000449408.2
ENST00000600871.1
ENST00000599124.1
FAM129C
family with sequence similarity 129, member C
chr17_-_61819121 0.06 ENST00000245865.5
ENST00000375840.4
ENST00000582137.1
ENST00000579549.1
ENST00000582030.1
ENST00000584110.1
ENST00000580288.1
ENST00000336174.6
ENST00000579340.1
ENST00000580338.1
STRADA
STE20-related kinase adaptor alpha
chr1_-_36615051 0.06 ENST00000373163.1
TRAPPC3
trafficking protein particle complex 3
chr3_+_52279902 0.06 ENST00000457454.1
PPM1M
protein phosphatase, Mg2+/Mn2+ dependent, 1M
chr16_+_28834531 0.06 ENST00000570200.1
ATXN2L
ataxin 2-like
chr19_-_51920873 0.06 ENST00000441969.3
ENST00000525998.1
ENST00000436984.2
SIGLEC10
sialic acid binding Ig-like lectin 10
chr1_+_155657737 0.06 ENST00000471642.2
ENST00000471214.1
DAP3
death associated protein 3
chr12_-_54813229 0.06 ENST00000293379.4
ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr17_-_61777090 0.06 ENST00000578061.1
LIMD2
LIM domain containing 2
chr6_-_31612808 0.06 ENST00000438149.1
BAG6
BCL2-associated athanogene 6
chr4_+_142557771 0.06 ENST00000514653.1
IL15
interleukin 15
chr14_+_75536335 0.06 ENST00000554763.1
ENST00000439583.2
ENST00000526130.1
ENST00000525046.1
ZC2HC1C
zinc finger, C2HC-type containing 1C
chr6_-_74230741 0.06 ENST00000316292.9
EEF1A1
eukaryotic translation elongation factor 1 alpha 1
chr20_+_1115821 0.06 ENST00000435720.1
PSMF1
proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
chr9_+_33817461 0.06 ENST00000263228.3
UBE2R2
ubiquitin-conjugating enzyme E2R 2
chr2_-_136743436 0.06 ENST00000441323.1
ENST00000449218.1
DARS
aspartyl-tRNA synthetase
chr3_+_63638372 0.06 ENST00000496807.1
SNTN
sentan, cilia apical structure protein
chrX_+_117861535 0.06 ENST00000371666.3
ENST00000371642.1
IL13RA1
interleukin 13 receptor, alpha 1
chrX_+_40440146 0.06 ENST00000535539.1
ENST00000378438.4
ENST00000436783.1
ENST00000544975.1
ENST00000535777.1
ENST00000447485.1
ENST00000423649.1
ATP6AP2
ATPase, H+ transporting, lysosomal accessory protein 2
chr6_+_163835669 0.06 ENST00000453779.2
ENST00000275262.7
ENST00000392127.2
ENST00000361752.3
QKI
QKI, KH domain containing, RNA binding
chr1_-_113249678 0.06 ENST00000369633.2
ENST00000425265.2
ENST00000369632.2
ENST00000436685.2
RHOC
ras homolog family member C
chr5_-_150521192 0.06 ENST00000523714.1
ENST00000521749.1
ANXA6
annexin A6
chr20_-_62462566 0.06 ENST00000245663.4
ENST00000302995.2
ZBTB46
zinc finger and BTB domain containing 46
chr4_-_120549163 0.06 ENST00000394439.1
ENST00000420633.1
PDE5A
phosphodiesterase 5A, cGMP-specific
chr4_-_76598326 0.06 ENST00000503660.1
G3BP2
GTPase activating protein (SH3 domain) binding protein 2
chr6_-_150039249 0.05 ENST00000543571.1
LATS1
large tumor suppressor kinase 1
chr5_-_127418755 0.05 ENST00000501702.2
ENST00000501173.2
ENST00000514573.1
ENST00000499346.2
ENST00000606251.1
CTC-228N24.3
CTC-228N24.3
chr2_+_202047843 0.05 ENST00000272879.5
ENST00000374650.3
ENST00000346817.5
ENST00000313728.7
ENST00000448480.1
CASP10
caspase 10, apoptosis-related cysteine peptidase
chr14_-_24615805 0.05 ENST00000560410.1
PSME2
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr10_+_89124746 0.05 ENST00000465545.1
NUTM2D
NUT family member 2D
chrX_-_15872914 0.05 ENST00000380291.1
ENST00000545766.1
ENST00000421527.2
ENST00000329235.2
AP1S2
adaptor-related protein complex 1, sigma 2 subunit
chr10_+_75668916 0.05 ENST00000481390.1
PLAU
plasminogen activator, urokinase
chr1_+_154301264 0.05 ENST00000341822.2
ATP8B2
ATPase, aminophospholipid transporter, class I, type 8B, member 2
chr15_+_22892663 0.05 ENST00000313077.7
ENST00000561274.1
ENST00000560848.1
CYFIP1
cytoplasmic FMR1 interacting protein 1
chr1_+_89990431 0.05 ENST00000330947.2
ENST00000358200.4
LRRC8B
leucine rich repeat containing 8 family, member B
chr13_+_97874574 0.05 ENST00000343600.4
ENST00000345429.6
ENST00000376673.3
MBNL2
muscleblind-like splicing regulator 2
chr1_+_205012293 0.05 ENST00000331830.4
CNTN2
contactin 2 (axonal)
chr9_+_82187487 0.05 ENST00000435650.1
ENST00000414465.1
ENST00000376537.4
ENST00000376534.4
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr3_-_194072019 0.05 ENST00000429275.1
ENST00000323830.3
CPN2
carboxypeptidase N, polypeptide 2
chr1_+_62417957 0.05 ENST00000307297.7
ENST00000543708.1
INADL
InaD-like (Drosophila)
chr1_+_38259459 0.05 ENST00000373045.6
MANEAL
mannosidase, endo-alpha-like
chr1_-_54304212 0.05 ENST00000540001.1
NDC1
NDC1 transmembrane nucleoporin
chr1_+_201979743 0.05 ENST00000446188.1
ELF3
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr6_-_17706618 0.05 ENST00000262077.2
ENST00000537253.1
NUP153
nucleoporin 153kDa
chr9_-_136344197 0.05 ENST00000414172.1
ENST00000371897.4
SLC2A6
solute carrier family 2 (facilitated glucose transporter), member 6
chr12_-_48499591 0.05 ENST00000551330.1
ENST00000004980.5
ENST00000339976.6
ENST00000448372.1
SENP1
SUMO1/sentrin specific peptidase 1
chr10_+_89419370 0.05 ENST00000361175.4
ENST00000456849.1
PAPSS2
3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr1_+_27114418 0.05 ENST00000078527.4
PIGV
phosphatidylinositol glycan anchor biosynthesis, class V
chr17_+_7590734 0.05 ENST00000457584.2
WRAP53
WD repeat containing, antisense to TP53
chr22_+_38349724 0.05 ENST00000470701.1
POLR2F
polymerase (RNA) II (DNA directed) polypeptide F
chr10_-_51623203 0.05 ENST00000444743.1
ENST00000374065.3
ENST00000374064.3
ENST00000260867.4
TIMM23
translocase of inner mitochondrial membrane 23 homolog (yeast)
chr19_+_4474846 0.05 ENST00000589486.1
ENST00000592691.1
HDGFRP2
Hepatoma-derived growth factor-related protein 2
chr6_+_18155632 0.05 ENST00000297792.5
KDM1B
lysine (K)-specific demethylase 1B
chr1_+_10093188 0.04 ENST00000377153.1
UBE4B
ubiquitination factor E4B
chr1_+_110453462 0.04 ENST00000488198.1
CSF1
colony stimulating factor 1 (macrophage)

Network of associatons between targets according to the STRING database.

First level regulatory network of NFKB1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0072573 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573) negative regulation of CD40 signaling pathway(GO:2000349)
0.1 0.4 GO:0045083 negative regulation of interleukin-12 biosynthetic process(GO:0045083)
0.1 0.3 GO:0042222 interleukin-1 biosynthetic process(GO:0042222) regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.1 0.3 GO:1904617 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
0.1 0.2 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.2 GO:0090222 centrosome-templated microtubule nucleation(GO:0090222)
0.1 0.2 GO:0070446 cellular response to caloric restriction(GO:0061433) negative regulation of oligodendrocyte progenitor proliferation(GO:0070446)
0.1 0.3 GO:0036343 psychomotor behavior(GO:0036343)
0.1 0.1 GO:0090291 negative regulation of osteoclast proliferation(GO:0090291)
0.1 0.2 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.1 0.4 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.1 0.4 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.0 0.2 GO:0003308 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308) embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.0 0.2 GO:0033590 response to cobalamin(GO:0033590)
0.0 0.9 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 0.3 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.1 GO:0051866 general adaptation syndrome(GO:0051866)
0.0 0.1 GO:0031296 B cell costimulation(GO:0031296)
0.0 0.1 GO:0045720 negative regulation of integrin biosynthetic process(GO:0045720)
0.0 0.2 GO:2001183 negative regulation of interleukin-12 secretion(GO:2001183)
0.0 0.2 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.0 0.1 GO:0070631 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.0 0.1 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.2 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.1 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.0 0.3 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.0 0.1 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.0 0.1 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.0 0.2 GO:2000546 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.0 0.2 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.0 0.2 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.0 0.2 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
0.0 0.1 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.0 0.1 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.0 0.5 GO:0002385 mucosal immune response(GO:0002385)
0.0 0.0 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.0 0.2 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.0 0.1 GO:0052250 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.0 0.1 GO:1990619 growth involved in heart morphogenesis(GO:0003241) positive regulation of chondrocyte proliferation(GO:1902732) histone H3-K9 deacetylation(GO:1990619)
0.0 0.1 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.0 0.2 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.2 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.0 0.3 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.1 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.0 0.1 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.0 0.1 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.0 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.0 0.3 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.0 GO:0046832 negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.0 0.0 GO:0032203 telomere formation via telomerase(GO:0032203)
0.0 0.1 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.0 0.1 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.0 0.1 GO:0042940 D-amino acid transport(GO:0042940)
0.0 0.2 GO:0070842 aggresome assembly(GO:0070842)
0.0 0.1 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
0.0 0.0 GO:0097476 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589) spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.0 0.0 GO:1904437 positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440)
0.0 0.0 GO:1990108 protein linear deubiquitination(GO:1990108)
0.0 0.0 GO:0060168 regulation of axon diameter(GO:0031133) positive regulation of adenosine receptor signaling pathway(GO:0060168)
0.0 0.0 GO:0045062 extrathymic T cell selection(GO:0045062)
0.0 0.0 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.0 GO:0000103 sulfate assimilation(GO:0000103)
0.0 0.1 GO:1903281 protein transport into plasma membrane raft(GO:0044861) positive regulation of calcium:sodium antiporter activity(GO:1903281) positive regulation of potassium ion import(GO:1903288)
0.0 0.1 GO:0035897 proteolysis in other organism(GO:0035897)
0.0 0.1 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0 0.1 GO:1903422 negative regulation of synaptic vesicle recycling(GO:1903422)
0.0 0.2 GO:0005981 regulation of glycogen catabolic process(GO:0005981)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.2 GO:0043196 varicosity(GO:0043196)
0.0 0.1 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
0.0 0.2 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.1 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.0 0.1 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.2 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.1 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.1 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 0.2 GO:0042587 glycogen granule(GO:0042587)
0.0 0.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.2 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.4 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.1 GO:0060091 kinocilium(GO:0060091)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.2 GO:0046970 NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0 0.9 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.2 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.0 0.1 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.0 0.1 GO:0050473 arachidonate 15-lipoxygenase activity(GO:0050473)
0.0 0.1 GO:0004911 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.0 0.1 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.1 GO:0016781 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.0 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.1 GO:0004915 interleukin-6 receptor activity(GO:0004915) leukemia inhibitory factor receptor activity(GO:0004923) interleukin-6 binding(GO:0019981)
0.0 0.1 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.1 GO:0032129 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.0 0.2 GO:0045159 myosin II binding(GO:0045159)
0.0 0.0 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.0 0.3 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.4 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.2 GO:0019211 phosphatase activator activity(GO:0019211) BMP receptor binding(GO:0070700)
0.0 0.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.2 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.0 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 0.1 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.4 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.1 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.3 GO:0031005 filamin binding(GO:0031005)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.8 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 1.1 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.1 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.2 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.3 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.3 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion