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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for NKX2-8

Z-value: 0.45

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Transcription factors associated with NKX2-8

Gene Symbol Gene ID Gene Info
NKX2-8
ENSG00000136327.6 NK2 homeobox 8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NKX2-8hg19_v2_chr14_-_37051798_370518310.821.8e-01Click!

Activity profile of NKX2-8 motif

Sorted Z-values of NKX2-8 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_25451065 0.28 ENST00000606328.1
RP11-458N5.1
RP11-458N5.1
chr17_+_73455788 0.28 ENST00000581519.1
KIAA0195
KIAA0195
chr17_+_76210367 0.27 ENST00000592734.1
ENST00000587746.1
BIRC5
baculoviral IAP repeat containing 5
chr1_+_180165672 0.27 ENST00000443059.1
QSOX1
quiescin Q6 sulfhydryl oxidase 1
chr6_-_32145861 0.22 ENST00000336984.6
AGPAT1
1-acylglycerol-3-phosphate O-acyltransferase 1
chr15_-_75248954 0.22 ENST00000499788.2
RPP25
ribonuclease P/MRP 25kDa subunit
chr11_-_67141640 0.22 ENST00000533438.1
CLCF1
cardiotrophin-like cytokine factor 1
chr16_+_88493879 0.19 ENST00000565624.1
ENST00000437464.1
ZNF469
zinc finger protein 469
chr19_+_2249308 0.18 ENST00000592877.1
ENST00000221496.4
AMH
anti-Mullerian hormone
chr1_+_154401791 0.18 ENST00000476006.1
IL6R
interleukin 6 receptor
chr22_-_21213676 0.18 ENST00000449120.1
PI4KA
phosphatidylinositol 4-kinase, catalytic, alpha
chr7_-_99716914 0.15 ENST00000431404.2
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr11_+_59705928 0.15 ENST00000398992.1
OOSP1
oocyte secreted protein 1
chr9_+_131873659 0.15 ENST00000452489.2
ENST00000347048.4
ENST00000357197.4
ENST00000445241.1
ENST00000355007.3
ENST00000414331.1
PPP2R4
protein phosphatase 2A activator, regulatory subunit 4
chr6_+_100054606 0.15 ENST00000369215.4
PRDM13
PR domain containing 13
chr7_+_150929550 0.14 ENST00000482173.1
ENST00000495645.1
ENST00000035307.2
CHPF2
chondroitin polymerizing factor 2
chr8_-_144679264 0.14 ENST00000531953.1
ENST00000526133.1
EEF1D
eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
chr7_-_156803329 0.14 ENST00000252971.6
MNX1
motor neuron and pancreas homeobox 1
chr16_-_75301886 0.14 ENST00000393422.2
BCAR1
breast cancer anti-estrogen resistance 1
chr11_+_35222629 0.14 ENST00000526553.1
CD44
CD44 molecule (Indian blood group)
chr17_+_46184911 0.13 ENST00000580219.1
ENST00000452859.2
ENST00000393405.2
ENST00000439357.2
ENST00000359238.2
SNX11
sorting nexin 11
chr16_+_28875268 0.13 ENST00000395532.4
SH2B1
SH2B adaptor protein 1
chr2_-_36779411 0.13 ENST00000406220.1
AC007401.2
Uncharacterized protein
chr20_+_55967129 0.12 ENST00000371219.2
RBM38
RNA binding motif protein 38
chr19_-_18391708 0.12 ENST00000600972.1
JUND
jun D proto-oncogene
chr2_-_132249955 0.12 ENST00000309451.6
MZT2A
mitotic spindle organizing protein 2A
chr16_+_28875126 0.12 ENST00000359285.5
ENST00000538342.1
SH2B1
SH2B adaptor protein 1
chr17_+_34901353 0.11 ENST00000593016.1
GGNBP2
gametogenetin binding protein 2
chr1_-_68698222 0.11 ENST00000370976.3
ENST00000354777.2
ENST00000262348.4
ENST00000540432.1
WLS
wntless Wnt ligand secretion mediator
chr18_+_3450161 0.11 ENST00000551402.1
ENST00000577543.1
TGIF1
TGFB-induced factor homeobox 1
chr12_+_49658855 0.11 ENST00000549183.1
TUBA1C
tubulin, alpha 1c
chr2_-_197675000 0.11 ENST00000342506.2
C2orf66
chromosome 2 open reading frame 66
chr7_+_99816859 0.11 ENST00000317271.2
PVRIG
poliovirus receptor related immunoglobulin domain containing
chr1_+_16083098 0.10 ENST00000496928.2
ENST00000508310.1
FBLIM1
filamin binding LIM protein 1
chr3_-_114790179 0.10 ENST00000462705.1
ZBTB20
zinc finger and BTB domain containing 20
chr17_-_202579 0.10 ENST00000577079.1
ENST00000331302.7
ENST00000536489.2
RPH3AL
rabphilin 3A-like (without C2 domains)
chr12_-_49504623 0.10 ENST00000550137.1
ENST00000547382.1
LMBR1L
limb development membrane protein 1-like
chr11_+_64808675 0.10 ENST00000529996.1
SAC3D1
SAC3 domain containing 1
chr17_+_46185111 0.10 ENST00000582104.1
ENST00000584335.1
SNX11
sorting nexin 11
chr11_-_117170403 0.10 ENST00000504995.1
BACE1
beta-site APP-cleaving enzyme 1
chr2_+_62132800 0.09 ENST00000538736.1
COMMD1
copper metabolism (Murr1) domain containing 1
chr22_+_38609538 0.09 ENST00000407965.1
MAFF
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
chr19_-_39322497 0.09 ENST00000221418.4
ECH1
enoyl CoA hydratase 1, peroxisomal
chr3_-_47950745 0.09 ENST00000429422.1
MAP4
microtubule-associated protein 4
chr12_-_49504655 0.09 ENST00000551782.1
ENST00000267102.8
LMBR1L
limb development membrane protein 1-like
chr4_-_164253738 0.09 ENST00000509586.1
ENST00000504391.1
ENST00000512819.1
NPY1R
neuropeptide Y receptor Y1
chrM_+_8366 0.09 ENST00000361851.1
MT-ATP8
mitochondrially encoded ATP synthase 8
chr21_+_33671264 0.09 ENST00000339944.4
MRAP
melanocortin 2 receptor accessory protein
chr9_+_109685630 0.09 ENST00000451160.2
RP11-508N12.4
Uncharacterized protein
chrX_+_48681768 0.09 ENST00000430858.1
HDAC6
histone deacetylase 6
chr1_+_16083123 0.09 ENST00000510393.1
ENST00000430076.1
FBLIM1
filamin binding LIM protein 1
chr17_+_73472575 0.08 ENST00000375248.5
KIAA0195
KIAA0195
chr8_-_61429315 0.08 ENST00000530725.1
ENST00000532232.1
RP11-163N6.2
RP11-163N6.2
chr22_+_29834572 0.08 ENST00000354373.2
RFPL1
ret finger protein-like 1
chr12_+_13349711 0.08 ENST00000538364.1
ENST00000396301.3
EMP1
epithelial membrane protein 1
chr19_-_39322299 0.08 ENST00000601094.1
ENST00000595567.1
ENST00000602115.1
ENST00000601778.1
ENST00000597205.1
ENST00000595470.1
ECH1
enoyl CoA hydratase 1, peroxisomal
chr6_+_30844192 0.08 ENST00000502955.1
ENST00000505066.1
DDR1
discoidin domain receptor tyrosine kinase 1
chr19_-_17622269 0.08 ENST00000595116.1
CTD-3131K8.2
CTD-3131K8.2
chr1_+_74701062 0.08 ENST00000326637.3
TNNI3K
TNNI3 interacting kinase
chr5_+_35852797 0.08 ENST00000508941.1
IL7R
interleukin 7 receptor
chr1_-_155006224 0.08 ENST00000368424.3
DCST2
DC-STAMP domain containing 2
chr14_+_92980111 0.08 ENST00000216487.7
ENST00000557762.1
RIN3
Ras and Rab interactor 3
chr12_+_50505762 0.07 ENST00000550487.1
ENST00000317943.2
COX14
cytochrome c oxidase assembly homolog 14 (S. cerevisiae)
chr19_+_36486078 0.07 ENST00000378887.2
SDHAF1
succinate dehydrogenase complex assembly factor 1
chr3_-_53290016 0.07 ENST00000423525.2
ENST00000423516.1
ENST00000296289.6
ENST00000462138.1
TKT
transketolase
chr19_+_34856078 0.07 ENST00000589399.1
ENST00000589640.1
ENST00000591204.1
GPI
glucose-6-phosphate isomerase
chr10_+_115674530 0.07 ENST00000451472.1
AL162407.1
CDNA FLJ20147 fis, clone COL07954; HCG1781466; Uncharacterized protein
chr17_+_8191815 0.07 ENST00000226105.6
ENST00000407006.4
ENST00000580434.1
ENST00000439238.3
RANGRF
RAN guanine nucleotide release factor
chr1_+_179050512 0.07 ENST00000367627.3
TOR3A
torsin family 3, member A
chr11_-_133826852 0.07 ENST00000533871.2
ENST00000321016.8
IGSF9B
immunoglobulin superfamily, member 9B
chr19_-_3600549 0.07 ENST00000589966.1
TBXA2R
thromboxane A2 receptor
chr5_+_92919043 0.07 ENST00000327111.3
NR2F1
nuclear receptor subfamily 2, group F, member 1
chr8_+_27182862 0.07 ENST00000521164.1
ENST00000346049.5
PTK2B
protein tyrosine kinase 2 beta
chr8_-_145018905 0.06 ENST00000398774.2
PLEC
plectin
chr14_-_88282595 0.06 ENST00000554519.1
RP11-1152H15.1
RP11-1152H15.1
chr8_+_128426535 0.06 ENST00000465342.2
POU5F1B
POU class 5 homeobox 1B
chrX_-_109590174 0.06 ENST00000372054.1
GNG5P2
guanine nucleotide binding protein (G protein), gamma 5 pseudogene 2
chr16_+_28874860 0.06 ENST00000545570.1
SH2B1
SH2B adaptor protein 1
chr12_+_121416489 0.06 ENST00000541395.1
ENST00000544413.1
HNF1A
HNF1 homeobox A
chr17_+_7591639 0.06 ENST00000396463.2
WRAP53
WD repeat containing, antisense to TP53
chr10_+_74653330 0.06 ENST00000334011.5
OIT3
oncoprotein induced transcript 3
chr7_-_766879 0.06 ENST00000537384.1
ENST00000417852.1
PRKAR1B
protein kinase, cAMP-dependent, regulatory, type I, beta
chr13_+_88325498 0.06 ENST00000400028.3
SLITRK5
SLIT and NTRK-like family, member 5
chr18_-_72920372 0.05 ENST00000581620.1
ENST00000582437.1
ZADH2
zinc binding alcohol dehydrogenase domain containing 2
chr12_-_102591604 0.05 ENST00000329406.4
PMCH
pro-melanin-concentrating hormone
chr3_+_126423045 0.05 ENST00000290913.3
ENST00000508789.1
CHCHD6
coiled-coil-helix-coiled-coil-helix domain containing 6
chrX_-_64196307 0.05 ENST00000545618.1
ZC4H2
zinc finger, C4H2 domain containing
chr15_-_99057551 0.05 ENST00000558256.1
FAM169B
family with sequence similarity 169, member B
chr22_+_20877924 0.05 ENST00000445189.1
MED15
mediator complex subunit 15
chr16_-_30441293 0.05 ENST00000565758.1
ENST00000567983.1
ENST00000319285.4
DCTPP1
dCTP pyrophosphatase 1
chr4_+_15341442 0.05 ENST00000397700.2
ENST00000295297.4
C1QTNF7
C1q and tumor necrosis factor related protein 7
chr3_+_47021168 0.05 ENST00000450053.3
ENST00000292309.5
ENST00000383740.2
NBEAL2
neurobeachin-like 2
chr6_-_32806506 0.05 ENST00000374897.2
ENST00000452392.2
TAP2
TAP2
transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
Uncharacterized protein
chr17_+_7591747 0.05 ENST00000534050.1
WRAP53
WD repeat containing, antisense to TP53
chr12_-_49504449 0.05 ENST00000547675.1
LMBR1L
limb development membrane protein 1-like
chr2_-_133429091 0.05 ENST00000345008.6
LYPD1
LY6/PLAUR domain containing 1
chr6_-_31830655 0.05 ENST00000375631.4
NEU1
sialidase 1 (lysosomal sialidase)
chrX_-_48776292 0.05 ENST00000376509.4
PIM2
pim-2 oncogene
chr2_+_101591314 0.05 ENST00000450763.1
NPAS2
neuronal PAS domain protein 2
chr12_+_66218212 0.05 ENST00000393578.3
ENST00000425208.2
ENST00000536545.1
ENST00000354636.3
HMGA2
high mobility group AT-hook 2
chr3_-_178103144 0.05 ENST00000417383.1
ENST00000418585.1
ENST00000411727.1
ENST00000439810.1
RP11-33A14.1
RP11-33A14.1
chr17_+_76210267 0.05 ENST00000301633.4
ENST00000350051.3
ENST00000374948.2
ENST00000590449.1
BIRC5
baculoviral IAP repeat containing 5
chr5_+_149737202 0.05 ENST00000451292.1
ENST00000377797.3
ENST00000445265.2
ENST00000323668.7
ENST00000439160.2
ENST00000394269.3
ENST00000427724.2
ENST00000504761.2
ENST00000513346.1
ENST00000515516.1
TCOF1
Treacher Collins-Franceschetti syndrome 1
chr1_+_113010056 0.04 ENST00000369686.5
WNT2B
wingless-type MMTV integration site family, member 2B
chr10_-_15762124 0.04 ENST00000378076.3
ITGA8
integrin, alpha 8
chr8_+_67341239 0.04 ENST00000320270.2
RRS1
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
chr1_+_43291220 0.04 ENST00000372514.3
ERMAP
erythroblast membrane-associated protein (Scianna blood group)
chr3_-_121740969 0.04 ENST00000393631.1
ENST00000273691.3
ENST00000344209.5
ILDR1
immunoglobulin-like domain containing receptor 1
chr17_+_39994032 0.04 ENST00000293303.4
ENST00000438813.1
KLHL10
kelch-like family member 10
chr15_-_70387120 0.04 ENST00000539550.1
TLE3
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chr1_+_55464600 0.04 ENST00000371265.4
BSND
Bartter syndrome, infantile, with sensorineural deafness (Barttin)
chr7_-_86974767 0.04 ENST00000610086.1
TP53TG1
TP53 target 1 (non-protein coding)
chr21_+_33671160 0.04 ENST00000303645.5
MRAP
melanocortin 2 receptor accessory protein
chr3_-_87039662 0.04 ENST00000494229.1
VGLL3
vestigial like 3 (Drosophila)
chr4_-_153601136 0.04 ENST00000504064.1
ENST00000304385.3
TMEM154
transmembrane protein 154
chr5_-_78281775 0.04 ENST00000396151.3
ENST00000565165.1
ARSB
arylsulfatase B
chr6_-_32731299 0.04 ENST00000435145.2
ENST00000437316.2
HLA-DQB2
major histocompatibility complex, class II, DQ beta 2
chr8_+_67405794 0.04 ENST00000522977.1
ENST00000480005.1
C8orf46
chromosome 8 open reading frame 46
chr22_+_39101728 0.04 ENST00000216044.5
ENST00000484657.1
GTPBP1
GTP binding protein 1
chr12_-_118406777 0.03 ENST00000339824.5
KSR2
kinase suppressor of ras 2
chr9_+_21409146 0.03 ENST00000380205.1
IFNA8
interferon, alpha 8
chr22_+_38453207 0.03 ENST00000404072.3
ENST00000424694.1
PICK1
protein interacting with PRKCA 1
chr17_-_46703826 0.03 ENST00000550387.1
ENST00000311177.5
HOXB9
homeobox B9
chr12_-_12837423 0.03 ENST00000540510.1
GPR19
G protein-coupled receptor 19
chr12_+_13349650 0.03 ENST00000256951.5
ENST00000431267.2
ENST00000542474.1
ENST00000544053.1
EMP1
epithelial membrane protein 1
chr2_-_68547019 0.03 ENST00000409862.1
CNRIP1
cannabinoid receptor interacting protein 1
chr1_-_95007193 0.03 ENST00000370207.4
ENST00000334047.7
F3
coagulation factor III (thromboplastin, tissue factor)
chr17_+_73642486 0.03 ENST00000579469.1
SMIM6
small integral membrane protein 6
chr22_-_50523760 0.03 ENST00000395876.2
MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr7_-_92855762 0.03 ENST00000453812.2
ENST00000394468.2
HEPACAM2
HEPACAM family member 2
chr13_+_108921977 0.03 ENST00000430559.1
ENST00000375887.4
TNFSF13B
tumor necrosis factor (ligand) superfamily, member 13b
chr1_+_76251912 0.03 ENST00000370826.3
RABGGTB
Rab geranylgeranyltransferase, beta subunit
chr3_-_180397256 0.03 ENST00000442201.2
CCDC39
coiled-coil domain containing 39
chr1_-_27998689 0.03 ENST00000339145.4
ENST00000362020.4
ENST00000361157.6
IFI6
interferon, alpha-inducible protein 6
chr3_-_187455680 0.03 ENST00000438077.1
BCL6
B-cell CLL/lymphoma 6
chr19_-_9003586 0.03 ENST00000380951.5
MUC16
mucin 16, cell surface associated
chr18_+_44497455 0.02 ENST00000592005.1
KATNAL2
katanin p60 subunit A-like 2
chr19_-_11347173 0.02 ENST00000587656.1
DOCK6
dedicator of cytokinesis 6
chr6_+_41010293 0.02 ENST00000373161.1
ENST00000373158.2
ENST00000470917.1
TSPO2
translocator protein 2
chr17_+_62503073 0.02 ENST00000580188.1
ENST00000581056.1
CEP95
centrosomal protein 95kDa
chrX_-_110655306 0.02 ENST00000371993.2
DCX
doublecortin
chr3_+_101498026 0.02 ENST00000495842.1
NXPE3
neurexophilin and PC-esterase domain family, member 3
chr11_-_104827425 0.02 ENST00000393150.3
CASP4
caspase 4, apoptosis-related cysteine peptidase
chr11_+_18417948 0.02 ENST00000542179.1
LDHA
lactate dehydrogenase A
chr13_-_46756351 0.02 ENST00000323076.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr6_+_125524785 0.02 ENST00000392482.2
TPD52L1
tumor protein D52-like 1
chr2_+_11752379 0.02 ENST00000396123.1
GREB1
growth regulation by estrogen in breast cancer 1
chr3_-_178984759 0.02 ENST00000349697.2
ENST00000497599.1
KCNMB3
potassium large conductance calcium-activated channel, subfamily M beta member 3
chr15_+_51973680 0.02 ENST00000542355.2
SCG3
secretogranin III
chr19_+_34856141 0.02 ENST00000586425.1
GPI
glucose-6-phosphate isomerase
chr17_-_8055747 0.02 ENST00000317276.4
ENST00000581703.1
PER1
period circadian clock 1
chr3_+_177545563 0.02 ENST00000434309.1
RP11-91K9.1
RP11-91K9.1
chr20_-_48747662 0.02 ENST00000371656.2
TMEM189
transmembrane protein 189
chr20_-_43936937 0.02 ENST00000342716.4
ENST00000353917.5
ENST00000360607.6
ENST00000372751.4
MATN4
matrilin 4
chr20_-_44485835 0.02 ENST00000457981.1
ENST00000426915.1
ENST00000217455.4
ACOT8
acyl-CoA thioesterase 8
chr15_+_93749295 0.02 ENST00000599897.1
AC112693.2
AC112693.2
chrX_+_41548220 0.02 ENST00000378142.4
GPR34
G protein-coupled receptor 34
chr17_+_61086917 0.02 ENST00000424789.2
ENST00000389520.4
TANC2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chrX_+_591524 0.02 ENST00000554971.1
ENST00000381575.1
SHOX
short stature homeobox
chr1_+_226013047 0.02 ENST00000366837.4
EPHX1
epoxide hydrolase 1, microsomal (xenobiotic)
chr10_-_118032979 0.02 ENST00000355422.6
GFRA1
GDNF family receptor alpha 1
chr3_-_8811288 0.02 ENST00000316793.3
ENST00000431493.1
OXTR
oxytocin receptor
chr4_+_184826418 0.02 ENST00000308497.4
ENST00000438269.1
STOX2
storkhead box 2
chr18_-_13915530 0.02 ENST00000327606.3
MC2R
melanocortin 2 receptor (adrenocorticotropic hormone)
chr16_+_8807419 0.02 ENST00000565016.1
ENST00000567812.1
ABAT
4-aminobutyrate aminotransferase
chrX_-_53461288 0.02 ENST00000375298.4
ENST00000375304.5
HSD17B10
hydroxysteroid (17-beta) dehydrogenase 10
chrX_-_72095808 0.02 ENST00000373529.5
DMRTC1
DMRT-like family C1
chr3_+_137728842 0.02 ENST00000183605.5
CLDN18
claudin 18
chr17_-_8198636 0.02 ENST00000577745.1
ENST00000579192.1
ENST00000396278.1
SLC25A35
solute carrier family 25, member 35
chr14_-_107219365 0.02 ENST00000424969.2
IGHV3-74
immunoglobulin heavy variable 3-74
chr5_-_179107975 0.02 ENST00000376974.4
CBY3
chibby homolog 3 (Drosophila)
chr2_-_68547061 0.01 ENST00000263655.3
CNRIP1
cannabinoid receptor interacting protein 1
chr1_-_94147385 0.01 ENST00000260502.6
BCAR3
breast cancer anti-estrogen resistance 3
chr15_-_60683326 0.01 ENST00000559350.1
ENST00000558986.1
ENST00000560389.1
ANXA2
annexin A2
chr15_-_28419569 0.01 ENST00000569772.1
HERC2
HECT and RLD domain containing E3 ubiquitin protein ligase 2
chr22_+_31518938 0.01 ENST00000412985.1
ENST00000331075.5
ENST00000412277.2
ENST00000420017.1
ENST00000400294.2
ENST00000405300.1
ENST00000404390.3
INPP5J
inositol polyphosphate-5-phosphatase J
chr12_-_46663734 0.01 ENST00000550173.1
SLC38A1
solute carrier family 38, member 1
chr14_-_58893876 0.01 ENST00000555097.1
ENST00000555404.1
TIMM9
translocase of inner mitochondrial membrane 9 homolog (yeast)
chr3_-_114343039 0.01 ENST00000481632.1
ZBTB20
zinc finger and BTB domain containing 20
chr2_+_177502438 0.01 ENST00000443670.1
AC017048.4
long intergenic non-protein coding RNA 1117
chr15_-_50558223 0.01 ENST00000267845.3
HDC
histidine decarboxylase
chr14_-_36990354 0.01 ENST00000518149.1
NKX2-1
NK2 homeobox 1
chr5_+_140474181 0.01 ENST00000194155.4
PCDHB2
protocadherin beta 2
chr8_+_104310661 0.01 ENST00000522566.1
FZD6
frizzled family receptor 6
chr1_-_104238912 0.01 ENST00000330330.5
AMY1B
amylase, alpha 1B (salivary)
chr1_+_12040238 0.01 ENST00000444836.1
ENST00000235329.5
MFN2
mitofusin 2
chr12_-_10320190 0.01 ENST00000543993.1
ENST00000339968.6
OLR1
oxidized low density lipoprotein (lectin-like) receptor 1
chr22_-_50523807 0.01 ENST00000442311.1
ENST00000538737.1
MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr8_+_23430157 0.01 ENST00000399967.3
FP15737
FP15737
chr3_-_139195350 0.01 ENST00000232217.2
RBP2
retinol binding protein 2, cellular
chr1_+_173793777 0.01 ENST00000239457.5
DARS2
aspartyl-tRNA synthetase 2, mitochondrial
chr3_+_187930719 0.01 ENST00000312675.4
LPP
LIM domain containing preferred translocation partner in lipoma
chr5_+_43602750 0.00 ENST00000505678.2
ENST00000512422.1
ENST00000264663.5
NNT
nicotinamide nucleotide transhydrogenase
chr12_+_66218598 0.00 ENST00000541363.1
HMGA2
high mobility group AT-hook 2
chrX_+_118533269 0.00 ENST00000336249.7
SLC25A43
solute carrier family 25, member 43
chr4_-_110723134 0.00 ENST00000510800.1
ENST00000512148.1
CFI
complement factor I
chr4_-_70080449 0.00 ENST00000446444.1
UGT2B11
UDP glucuronosyltransferase 2 family, polypeptide B11
chr10_-_135171178 0.00 ENST00000368551.1
FUOM
fucose mutarotase
chr1_+_41157361 0.00 ENST00000427410.2
ENST00000447388.3
ENST00000425457.2
ENST00000453631.1
ENST00000456393.2
NFYC
nuclear transcription factor Y, gamma
chr14_+_58894404 0.00 ENST00000554463.1
ENST00000555833.1
KIAA0586
KIAA0586

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX2-8

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0007506 gonadal mesoderm development(GO:0007506)
0.0 0.2 GO:0002384 hepatic immune response(GO:0002384)
0.0 0.1 GO:0032203 telomere formation via telomerase(GO:0032203)
0.0 0.1 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.0 0.1 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.0 0.2 GO:0048295 positive regulation of isotype switching to IgE isotypes(GO:0048295)
0.0 0.1 GO:0034553 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.0 0.1 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.0 0.1 GO:0070846 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.0 0.1 GO:0035623 renal glucose absorption(GO:0035623)
0.0 0.1 GO:0019242 methylglyoxal biosynthetic process(GO:0019242)
0.0 0.1 GO:0005997 xylulose metabolic process(GO:0005997) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.0 0.0 GO:0002476 antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476)
0.0 0.1 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.3 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.0 0.0 GO:0061580 colon epithelial cell migration(GO:0061580)
0.0 0.2 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.1 GO:2000538 regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.0 0.0 GO:0048808 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0 0.2 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.1 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0 0.1 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.1 GO:0009213 pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0070110 ciliary neurotrophic factor receptor complex(GO:0070110)
0.0 0.2 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 0.3 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.2 GO:0019034 viral replication complex(GO:0019034)
0.0 0.2 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.1 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
0.0 0.1 GO:0035976 AP1 complex(GO:0035976)
0.0 0.1 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.1 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.1 0.3 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.1 GO:0031781 melanocortin receptor binding(GO:0031779) corticotropin hormone receptor binding(GO:0031780) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782) type 5 melanocortin receptor binding(GO:0031783) type 1 melanocortin receptor binding(GO:0070996)
0.0 0.1 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.1 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.0 0.2 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.1 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.0 0.1 GO:0004961 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.0 0.1 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.2 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.1 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.0 0.1 GO:0004347 glucose-6-phosphate isomerase activity(GO:0004347)
0.0 0.0 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.1 GO:0031013 troponin I binding(GO:0031013)
0.0 0.0 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.1 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.0 0.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.1 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling