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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for NR1D1

Z-value: 0.49

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Transcription factors associated with NR1D1

Gene Symbol Gene ID Gene Info
NR1D1
ENSG00000126368.5 nuclear receptor subfamily 1 group D member 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR1D1hg19_v2_chr17_-_38256973_382569900.297.1e-01Click!

Activity profile of NR1D1 motif

Sorted Z-values of NR1D1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_123755639 0.21 ENST00000535979.1
CDK2AP1
cyclin-dependent kinase 2 associated protein 1
chr12_+_57854274 0.19 ENST00000528432.1
GLI1
GLI family zinc finger 1
chr14_-_50999307 0.18 ENST00000013125.4
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr12_-_110883346 0.17 ENST00000547365.1
ARPC3
actin related protein 2/3 complex, subunit 3, 21kDa
chr19_+_21203426 0.16 ENST00000261560.5
ENST00000599548.1
ENST00000594110.1
ZNF430
zinc finger protein 430
chr7_-_46521173 0.16 ENST00000440935.1
AC004869.2
AC004869.2
chr1_+_111992064 0.15 ENST00000483994.1
ATP5F1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1
chr9_+_116343192 0.15 ENST00000471324.2
RGS3
regulator of G-protein signaling 3
chr3_-_117716418 0.15 ENST00000484092.1
RP11-384F7.2
RP11-384F7.2
chr1_-_154178803 0.14 ENST00000368525.3
C1orf189
chromosome 1 open reading frame 189
chr6_-_27440837 0.14 ENST00000211936.6
ZNF184
zinc finger protein 184
chr19_-_51220176 0.14 ENST00000359082.3
ENST00000293441.1
SHANK1
SH3 and multiple ankyrin repeat domains 1
chr2_-_64371546 0.13 ENST00000358912.4
PELI1
pellino E3 ubiquitin protein ligase 1
chr8_+_11561660 0.13 ENST00000526716.1
ENST00000335135.4
ENST00000528027.1
GATA4
GATA binding protein 4
chr1_-_26233423 0.13 ENST00000357865.2
STMN1
stathmin 1
chr1_-_26232522 0.12 ENST00000399728.1
STMN1
stathmin 1
chr1_+_203764742 0.11 ENST00000432282.1
ENST00000453771.1
ENST00000367214.1
ENST00000367212.3
ENST00000332127.4
ZC3H11A
zinc finger CCCH-type containing 11A
chr2_+_63816126 0.11 ENST00000454035.1
MDH1
malate dehydrogenase 1, NAD (soluble)
chr2_+_113342011 0.11 ENST00000324913.5
CHCHD5
coiled-coil-helix-coiled-coil-helix domain containing 5
chr3_-_182703688 0.10 ENST00000466812.1
ENST00000487822.1
ENST00000460412.1
ENST00000469954.1
DCUN1D1
DCN1, defective in cullin neddylation 1, domain containing 1
chrY_+_2803322 0.10 ENST00000383052.1
ENST00000155093.3
ENST00000449237.1
ENST00000443793.1
ZFY
zinc finger protein, Y-linked
chr7_+_64126535 0.10 ENST00000344930.3
ZNF107
zinc finger protein 107
chr19_+_22235279 0.10 ENST00000594363.1
ENST00000597927.1
ENST00000594947.1
ZNF257
zinc finger protein 257
chr1_-_32403903 0.10 ENST00000344035.6
ENST00000356536.3
PTP4A2
protein tyrosine phosphatase type IVA, member 2
chr17_-_38074842 0.10 ENST00000309481.7
GSDMB
gasdermin B
chr9_+_136243264 0.10 ENST00000371955.1
C9orf96
chromosome 9 open reading frame 96
chr10_-_8095412 0.10 ENST00000458727.1
ENST00000355358.1
RP11-379F12.3
GATA3-AS1
RP11-379F12.3
GATA3 antisense RNA 1
chr5_-_43313574 0.10 ENST00000325110.6
ENST00000433297.2
HMGCS1
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr1_+_110210644 0.10 ENST00000369831.2
ENST00000442650.1
ENST00000369827.3
ENST00000460717.3
ENST00000241337.4
ENST00000467579.3
ENST00000414179.2
ENST00000369829.2
GSTM2
glutathione S-transferase mu 2 (muscle)
chr11_-_125365435 0.09 ENST00000524435.1
FEZ1
fasciculation and elongation protein zeta 1 (zygin I)
chr1_+_218519577 0.09 ENST00000366930.4
ENST00000366929.4
TGFB2
transforming growth factor, beta 2
chr7_+_94139105 0.09 ENST00000297273.4
CASD1
CAS1 domain containing 1
chr1_-_150944411 0.09 ENST00000368949.4
CERS2
ceramide synthase 2
chr10_+_23217006 0.08 ENST00000376528.4
ENST00000447081.1
ARMC3
armadillo repeat containing 3
chr14_+_100789669 0.08 ENST00000361529.3
ENST00000557052.1
SLC25A47
solute carrier family 25, member 47
chr1_-_26232951 0.08 ENST00000426559.2
ENST00000455785.2
STMN1
stathmin 1
chr22_+_45898712 0.08 ENST00000455233.1
ENST00000348697.2
ENST00000402984.3
ENST00000262722.7
ENST00000327858.6
ENST00000442170.2
ENST00000340923.5
ENST00000439835.1
FBLN1
fibulin 1
chr9_+_91150016 0.08 ENST00000375854.3
ENST00000375855.3
NXNL2
nucleoredoxin-like 2
chr3_+_169755715 0.08 ENST00000355897.5
GPR160
G protein-coupled receptor 160
chrX_-_49089771 0.08 ENST00000376251.1
ENST00000323022.5
ENST00000376265.2
CACNA1F
calcium channel, voltage-dependent, L type, alpha 1F subunit
chr15_-_65903574 0.08 ENST00000420799.2
ENST00000313182.2
ENST00000431261.2
ENST00000442903.3
VWA9
von Willebrand factor A domain containing 9
chr2_+_63816269 0.08 ENST00000432309.1
MDH1
malate dehydrogenase 1, NAD (soluble)
chr16_+_71392616 0.08 ENST00000349553.5
ENST00000302628.4
ENST00000562305.1
CALB2
calbindin 2
chr7_+_114562172 0.08 ENST00000393486.1
ENST00000257724.3
MDFIC
MyoD family inhibitor domain containing
chr10_+_23216944 0.08 ENST00000298032.5
ENST00000409983.3
ENST00000409049.3
ARMC3
armadillo repeat containing 3
chr1_+_2398876 0.07 ENST00000449969.1
PLCH2
phospholipase C, eta 2
chr19_+_21264943 0.07 ENST00000597424.1
ZNF714
zinc finger protein 714
chr8_+_101162812 0.07 ENST00000353107.3
ENST00000522439.1
POLR2K
polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa
chr11_-_125366018 0.07 ENST00000527534.1
FEZ1
fasciculation and elongation protein zeta 1 (zygin I)
chr1_+_159796534 0.07 ENST00000289707.5
SLAMF8
SLAM family member 8
chr17_+_6900201 0.07 ENST00000480801.1
ALOX12
arachidonate 12-lipoxygenase
chr15_-_65903512 0.07 ENST00000567923.1
VWA9
von Willebrand factor A domain containing 9
chr7_-_100493744 0.06 ENST00000428317.1
ENST00000441605.1
ACHE
acetylcholinesterase (Yt blood group)
chr3_+_171758344 0.06 ENST00000336824.4
ENST00000423424.1
FNDC3B
fibronectin type III domain containing 3B
chr19_-_4455290 0.06 ENST00000394765.3
ENST00000592515.1
UBXN6
UBX domain protein 6
chr16_-_18468926 0.06 ENST00000545114.1
RP11-1212A22.4
LOC339047 protein; Nuclear pore complex-interacting protein family member A3; Nuclear pore complex-interacting protein family member A5; Protein PKD1P1
chr3_-_45957088 0.06 ENST00000539217.1
LZTFL1
leucine zipper transcription factor-like 1
chr19_+_39647271 0.06 ENST00000599657.1
PAK4
p21 protein (Cdc42/Rac)-activated kinase 4
chr4_-_21699380 0.06 ENST00000382148.3
KCNIP4
Kv channel interacting protein 4
chr1_+_161719552 0.06 ENST00000367943.4
DUSP12
dual specificity phosphatase 12
chr10_+_90346519 0.06 ENST00000371939.3
LIPJ
lipase, family member J
chr1_-_11865982 0.06 ENST00000418034.1
MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr6_+_63921351 0.05 ENST00000370659.1
FKBP1C
FK506 binding protein 1C
chr17_-_38256973 0.05 ENST00000246672.3
NR1D1
nuclear receptor subfamily 1, group D, member 1
chrX_+_16964985 0.05 ENST00000303843.7
REPS2
RALBP1 associated Eps domain containing 2
chr5_+_154173697 0.05 ENST00000518742.1
LARP1
La ribonucleoprotein domain family, member 1
chr6_+_31543334 0.05 ENST00000449264.2
TNF
tumor necrosis factor
chr1_-_226374373 0.05 ENST00000366812.5
ACBD3
acyl-CoA binding domain containing 3
chr13_+_27844464 0.05 ENST00000241463.4
RASL11A
RAS-like, family 11, member A
chr19_+_21265028 0.05 ENST00000291770.7
ZNF714
zinc finger protein 714
chr1_-_6557156 0.05 ENST00000537245.1
PLEKHG5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr1_-_197169672 0.05 ENST00000367405.4
ZBTB41
zinc finger and BTB domain containing 41
chr11_+_7534999 0.05 ENST00000528947.1
ENST00000299492.4
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr7_-_100493482 0.05 ENST00000411582.1
ENST00000419336.2
ENST00000241069.5
ENST00000302913.4
ACHE
acetylcholinesterase (Yt blood group)
chr2_+_103353367 0.05 ENST00000454536.1
ENST00000409528.1
ENST00000409173.1
TMEM182
transmembrane protein 182
chr17_+_43922241 0.04 ENST00000329196.5
SPPL2C
signal peptide peptidase like 2C
chr17_-_38074859 0.04 ENST00000520542.1
ENST00000418519.1
ENST00000394179.1
GSDMB
gasdermin B
chr16_+_67233007 0.04 ENST00000360833.1
ENST00000393997.2
ELMO3
engulfment and cell motility 3
chr18_-_19284724 0.04 ENST00000580981.1
ENST00000289119.2
ABHD3
abhydrolase domain containing 3
chr16_+_67233412 0.04 ENST00000477898.1
ELMO3
engulfment and cell motility 3
chr18_-_5892103 0.04 ENST00000383490.2
TMEM200C
transmembrane protein 200C
chrX_+_24167828 0.04 ENST00000379188.3
ENST00000419690.1
ENST00000379177.1
ENST00000304543.5
ZFX
zinc finger protein, X-linked
chr5_-_43313269 0.04 ENST00000511774.1
HMGCS1
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr19_-_43702231 0.04 ENST00000597374.1
ENST00000599371.1
PSG4
pregnancy specific beta-1-glycoprotein 4
chr17_-_3599327 0.04 ENST00000551178.1
ENST00000552276.1
ENST00000547178.1
P2RX5
purinergic receptor P2X, ligand-gated ion channel, 5
chr7_-_37488547 0.04 ENST00000453399.1
ELMO1
engulfment and cell motility 1
chrX_+_16964794 0.04 ENST00000357277.3
REPS2
RALBP1 associated Eps domain containing 2
chr14_+_24540731 0.04 ENST00000558859.1
ENST00000559197.1
ENST00000560828.1
ENST00000216775.2
ENST00000560884.1
CPNE6
copine VI (neuronal)
chr19_-_18995029 0.03 ENST00000596048.1
CERS1
ceramide synthase 1
chr1_-_38218577 0.03 ENST00000540011.1
EPHA10
EPH receptor A10
chr7_+_64126503 0.03 ENST00000360117.3
ZNF107
zinc finger protein 107
chr17_+_39405939 0.03 ENST00000334109.2
KRTAP9-4
keratin associated protein 9-4
chr4_+_1873155 0.03 ENST00000507820.1
ENST00000514045.1
WHSC1
Wolf-Hirschhorn syndrome candidate 1
chr2_+_203776937 0.03 ENST00000402905.3
ENST00000414490.1
ENST00000431787.1
ENST00000444724.1
ENST00000414857.1
ENST00000430899.1
ENST00000445120.1
ENST00000441569.1
ENST00000432024.1
ENST00000443740.1
ENST00000414439.1
ENST00000428585.1
ENST00000545253.1
ENST00000545262.1
ENST00000447539.1
ENST00000456821.2
ENST00000434998.1
ENST00000320443.8
CARF
calcium responsive transcription factor
chr3_-_133648656 0.03 ENST00000408895.2
C3orf36
chromosome 3 open reading frame 36
chr13_+_100741269 0.03 ENST00000376286.4
ENST00000376279.3
ENST00000376285.1
PCCA
propionyl CoA carboxylase, alpha polypeptide
chr9_-_35112376 0.03 ENST00000488109.2
FAM214B
family with sequence similarity 214, member B
chr22_-_28316116 0.03 ENST00000415296.1
PITPNB
phosphatidylinositol transfer protein, beta
chr19_+_21203481 0.02 ENST00000595401.1
ZNF430
zinc finger protein 430
chr19_-_12833361 0.02 ENST00000592287.1
TNPO2
transportin 2
chr13_+_113623509 0.02 ENST00000535094.2
MCF2L
MCF.2 cell line derived transforming sequence-like
chr9_-_136242956 0.02 ENST00000371989.3
ENST00000485435.2
SURF4
surfeit 4
chr11_+_46366799 0.02 ENST00000532868.2
DGKZ
diacylglycerol kinase, zeta
chr11_+_46740730 0.02 ENST00000311907.5
ENST00000530231.1
ENST00000442468.1
F2
coagulation factor II (thrombin)
chr3_-_52002403 0.02 ENST00000490063.1
ENST00000468324.1
ENST00000497653.1
ENST00000484633.1
PCBP4
poly(rC) binding protein 4
chr19_+_21264980 0.02 ENST00000596053.1
ENST00000597086.1
ENST00000596143.1
ENST00000596367.1
ENST00000601416.1
ZNF714
zinc finger protein 714
chr14_+_50999744 0.02 ENST00000441560.2
ATL1
atlastin GTPase 1
chr14_+_74815116 0.02 ENST00000256362.4
VRTN
vertebrae development associated
chr17_-_74528128 0.02 ENST00000590175.1
CYGB
cytoglobin
chr10_+_11047259 0.02 ENST00000379261.4
ENST00000416382.2
CELF2
CUGBP, Elav-like family member 2
chr3_-_52002194 0.02 ENST00000466412.1
PCBP4
poly(rC) binding protein 4
chr6_+_167525277 0.02 ENST00000400926.2
CCR6
chemokine (C-C motif) receptor 6
chr22_-_20138302 0.01 ENST00000540078.1
ENST00000439765.2
AC006547.14
uncharacterized protein LOC388849
chr6_-_31938700 0.01 ENST00000495340.1
DXO
decapping exoribonuclease
chr1_-_111991908 0.01 ENST00000235090.5
WDR77
WD repeat domain 77
chr10_-_43762329 0.01 ENST00000395810.1
RASGEF1A
RasGEF domain family, member 1A
chr19_-_58071201 0.01 ENST00000325134.5
ENST00000457177.1
ZNF550
zinc finger protein 550
chr19_+_21688366 0.01 ENST00000358491.4
ENST00000597078.1
ZNF429
zinc finger protein 429
chr9_-_136242909 0.01 ENST00000371991.3
ENST00000545297.1
SURF4
surfeit 4
chr15_-_65903407 0.01 ENST00000395644.4
ENST00000567744.1
ENST00000568573.1
ENST00000562830.1
ENST00000569491.1
ENST00000561769.1
VWA9
von Willebrand factor A domain containing 9
chr6_+_76458909 0.01 ENST00000369981.3
ENST00000369985.4
MYO6
myosin VI
chr11_+_125365110 0.01 ENST00000527818.1
AP000708.1
AP000708.1
chr19_+_38880695 0.01 ENST00000587947.1
ENST00000338502.4
SPRED3
sprouty-related, EVH1 domain containing 3
chr2_+_63816087 0.01 ENST00000409908.1
ENST00000442225.1
ENST00000409476.1
ENST00000436321.1
MDH1
malate dehydrogenase 1, NAD (soluble)
chr6_+_99282570 0.00 ENST00000328345.5
POU3F2
POU class 3 homeobox 2
chr17_-_79139817 0.00 ENST00000326724.4
AATK
apoptosis-associated tyrosine kinase
chrX_+_24167746 0.00 ENST00000428571.1
ENST00000539115.1
ZFX
zinc finger protein, X-linked
chr6_-_135424186 0.00 ENST00000529882.1
HBS1L
HBS1-like (S. cerevisiae)
chr6_+_76458990 0.00 ENST00000369977.3
MYO6
myosin VI
chr2_-_73053126 0.00 ENST00000272427.6
ENST00000410104.1
EXOC6B
exocyst complex component 6B
chr17_-_59940705 0.00 ENST00000577913.1
BRIP1
BRCA1 interacting protein C-terminal helicase 1
chr9_+_101569944 0.00 ENST00000375011.3
GALNT12
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 12 (GalNAc-T12)
chr2_+_63816295 0.00 ENST00000539945.1
ENST00000544381.1
MDH1
malate dehydrogenase 1, NAD (soluble)
chr9_+_103790991 0.00 ENST00000374874.3
LPPR1
Lipid phosphate phosphatase-related protein type 1
chr1_-_1690014 0.00 ENST00000400922.2
ENST00000342348.5
NADK
NAD kinase
chr19_+_21324827 0.00 ENST00000600692.1
ENST00000599296.1
ENST00000594425.1
ENST00000311048.7
ZNF431
zinc finger protein 431
chr11_+_46366918 0.00 ENST00000528615.1
ENST00000395574.3
DGKZ
diacylglycerol kinase, zeta

Network of associatons between targets according to the STRING database.

First level regulatory network of NR1D1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.0 0.2 GO:0060032 notochord regression(GO:0060032)
0.0 0.2 GO:0003284 septum primum development(GO:0003284) atrial septum primum morphogenesis(GO:0003289)
0.0 0.1 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.0 0.1 GO:1905044 Schwann cell proliferation involved in axon regeneration(GO:0014011) negative regulation of Schwann cell migration(GO:1900148) regulation of Schwann cell proliferation involved in axon regeneration(GO:1905044) negative regulation of Schwann cell proliferation involved in axon regeneration(GO:1905045)
0.0 0.1 GO:1903565 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.0 0.1 GO:0050893 sensory processing(GO:0050893)
0.0 0.1 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.1 GO:0060086 circadian temperature homeostasis(GO:0060086)
0.0 0.1 GO:1904833 chronic inflammatory response to antigenic stimulus(GO:0002439) positive regulation of translational initiation by iron(GO:0045994) positive regulation of superoxide dismutase activity(GO:1901671) positive regulation of removal of superoxide radicals(GO:1904833)
0.0 0.1 GO:0070458 cellular detoxification of nitrogen compound(GO:0070458)
0.0 0.2 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.0 GO:0072720 cellular response to mycotoxin(GO:0036146) response to dithiothreitol(GO:0072720)
0.0 0.2 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0047860 diiodophenylpyruvate reductase activity(GO:0047860)
0.0 0.1 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 0.1 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.0 0.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.1 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.1 GO:0015199 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0 0.1 GO:0070051 fibrinogen binding(GO:0070051)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.1 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.1 GO:0051525 NFAT protein binding(GO:0051525)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta