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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for OTX1

Z-value: 0.23

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Transcription factors associated with OTX1

Gene Symbol Gene ID Gene Info
ENSG00000115507.5 orthodenticle homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
OTX1hg19_v2_chr2_+_63277927_63277938-0.346.6e-01Click!

Activity profile of OTX1 motif

Sorted Z-values of OTX1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_26251835 0.11 ENST00000356350.2
histone cluster 1, H2bh
chr1_-_204116078 0.07 ENST00000367198.2
ENST00000452983.1
ethanolamine kinase 2
chr3_-_12587055 0.07 ENST00000564146.3
chromosome 3 open reading frame 83
chr10_-_104211294 0.07 ENST00000239125.1
chromosome 10 open reading frame 95
chr11_-_85376121 0.06 ENST00000527447.1
CREB/ATF bZIP transcription factor
chr16_-_29874211 0.06 ENST00000563415.1
CDP-diacylglycerol--inositol 3-phosphatidyltransferase
chr3_+_111393501 0.05 ENST00000393934.3
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr14_-_65769392 0.05 ENST00000555736.1
CTD-2509G16.5
chr9_-_35563896 0.05 ENST00000399742.2
family with sequence similarity 166, member B
chr19_-_16008880 0.05 ENST00000011989.7
ENST00000221700.6
cytochrome P450, family 4, subfamily F, polypeptide 2
chr1_-_247335269 0.05 ENST00000543802.2
ENST00000491356.1
ENST00000472531.1
ENST00000340684.6
zinc finger protein 124
chr17_+_41476327 0.04 ENST00000320033.4
ADP-ribosylation factor-like 4D
chr16_-_21452040 0.04 ENST00000521589.1
nuclear pore complex interacting protein family, member B3
chr6_+_26204825 0.04 ENST00000360441.4
histone cluster 1, H4e
chr19_-_47616992 0.04 ENST00000253048.5
zinc finger CCCH-type containing 4
chr6_+_35420091 0.04 ENST00000229769.2
Fanconi anemia, complementation group E
chr8_-_145652336 0.04 ENST00000529182.1
ENST00000526054.1
vacuolar protein sorting 28 homolog (S. cerevisiae)
chr3_+_188664988 0.04 ENST00000433971.1
tumor protein p63 regulated 1
chr5_+_59783941 0.04 ENST00000506884.1
ENST00000504876.2
prostate androgen-regulated transcript 1 (non-protein coding)
chr16_-_29874462 0.04 ENST00000566113.1
ENST00000569956.1
ENST00000570016.1
CDP-diacylglycerol--inositol 3-phosphatidyltransferase
chr19_+_10381769 0.04 ENST00000423829.2
ENST00000588645.1
intercellular adhesion molecule 1
chr16_-_29875057 0.04 ENST00000219789.6
CDP-diacylglycerol--inositol 3-phosphatidyltransferase
chr7_+_1609765 0.03 ENST00000437964.1
ENST00000533935.1
ENST00000532358.1
ENST00000524978.1
PSMG3 antisense RNA 1 (head to head)
chr19_-_46580352 0.03 ENST00000601672.1
IGF-like family member 4
chr12_-_130529501 0.03 ENST00000561864.1
ENST00000567788.1
RP11-474D1.4
RP11-474D1.3
chr21_+_18811205 0.03 ENST00000440664.1
chromosome 21 open reading frame 37
chr17_+_43971643 0.03 ENST00000344290.5
ENST00000262410.5
ENST00000351559.5
ENST00000340799.5
ENST00000535772.1
ENST00000347967.5
microtubule-associated protein tau
chr19_+_17448348 0.03 ENST00000324894.8
ENST00000358792.7
ENST00000600625.1
GTP binding protein 3 (mitochondrial)
chr17_+_41158742 0.03 ENST00000415816.2
ENST00000438323.2
interferon-induced protein 35
chr19_+_47616682 0.03 ENST00000594526.1
SUMO1 activating enzyme subunit 1
chr14_-_75083313 0.03 ENST00000556652.1
ENST00000555313.1
CTD-2207P18.2
chr2_-_14541060 0.03 ENST00000418420.1
ENST00000417751.1
long intergenic non-protein coding RNA 276
chr16_-_69373396 0.03 ENST00000562595.1
ENST00000562081.1
ENST00000306875.4
component of oligomeric golgi complex 8
chr4_-_112993808 0.03 ENST00000511219.1
RP11-269F21.3
chr22_-_30162924 0.02 ENST00000344318.3
ENST00000397781.3
zinc finger, matrin-type 5
chr11_+_119205222 0.02 ENST00000311413.4
ring finger protein 26
chr19_-_41903161 0.02 ENST00000602129.1
ENST00000593771.1
ENST00000596905.1
ENST00000221233.4
exosome component 5
chr20_+_9146969 0.02 ENST00000416836.1
phospholipase C, beta 4
chr1_-_9811600 0.02 ENST00000435891.1
calsyntenin 1
chr11_+_113258495 0.02 ENST00000303941.3
ankyrin repeat and kinase domain containing 1
chr19_-_55677920 0.02 ENST00000524407.2
ENST00000526003.1
ENST00000534170.1
dynein, axonemal, assembly factor 3
chr11_+_128563652 0.02 ENST00000527786.2
Fli-1 proto-oncogene, ETS transcription factor
chr18_-_59274139 0.02 ENST00000586949.1
RP11-879F14.2
chr12_+_49740700 0.02 ENST00000549441.2
ENST00000395069.3
DnaJ (Hsp40) homolog, subfamily C, member 22
chr1_+_74701062 0.02 ENST00000326637.3
TNNI3 interacting kinase
chr12_-_11214893 0.02 ENST00000533467.1
taste receptor, type 2, member 46
chr11_-_62420757 0.02 ENST00000330574.2
integrator complex subunit 5
chr8_+_109455830 0.02 ENST00000524143.1
ER membrane protein complex subunit 2
chr3_+_111393659 0.02 ENST00000477665.1
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr8_+_35649365 0.02 ENST00000437887.1
Uncharacterized protein
chr19_-_55677999 0.02 ENST00000532817.1
ENST00000527223.2
ENST00000391720.4
dynein, axonemal, assembly factor 3
chr16_+_58033450 0.02 ENST00000561743.1
U6 snRNA biogenesis 1
chr15_-_80695917 0.02 ENST00000559008.1
Uncharacterized protein
chr1_-_146696901 0.02 ENST00000369272.3
ENST00000441068.2
flavin containing monooxygenase 5
chr4_+_75174180 0.02 ENST00000413830.1
epithelial mitogen
chr19_+_35940486 0.02 ENST00000246549.2
free fatty acid receptor 2
chr5_+_135496675 0.02 ENST00000507637.1
SMAD family member 5
chr6_+_106546808 0.02 ENST00000369089.3
PR domain containing 1, with ZNF domain
chrX_-_134156502 0.02 ENST00000391440.1
family with sequence similarity 127, member C
chr17_+_5981270 0.01 ENST00000571973.1
WSC domain containing 1
chrX_-_100307043 0.01 ENST00000372939.1
ENST00000372935.1
ENST00000372936.3
tRNA methyltransferase 2 homolog B (S. cerevisiae)
chr5_-_66942617 0.01 ENST00000507298.1
RP11-83M16.5
chr8_-_33370607 0.01 ENST00000360742.5
ENST00000523305.1
TELO2 interacting protein 2
chr16_-_8962200 0.01 ENST00000562843.1
ENST00000561530.1
ENST00000396593.2
calcium regulated heat stable protein 1, 24kDa
chr11_-_67276100 0.01 ENST00000301488.3
cyclin-dependent kinase 2 associated protein 2
chr1_-_92351769 0.01 ENST00000212355.4
transforming growth factor, beta receptor III
chr7_+_99195878 0.01 ENST00000453227.1
ENST00000429679.1
GS1-259H13.2
chr2_+_170335924 0.01 ENST00000554017.1
ENST00000392663.2
ENST00000513963.1
Bardet-Biedl syndrome 5
Bardet-Biedl syndrome 5 protein; Uncharacterized protein
chr4_-_83769996 0.01 ENST00000511338.1
SEC31 homolog A (S. cerevisiae)
chr19_+_41903709 0.01 ENST00000542943.1
ENST00000457836.2
branched chain keto acid dehydrogenase E1, alpha polypeptide
chr12_+_57881740 0.01 ENST00000262027.5
ENST00000315473.5
methionyl-tRNA synthetase
chr14_-_102706934 0.01 ENST00000523231.1
ENST00000524370.1
ENST00000517966.1
MOK protein kinase
chr1_+_241695670 0.01 ENST00000366557.4
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr2_-_74618964 0.01 ENST00000417090.1
ENST00000409868.1
dynactin 1
chr7_+_120702819 0.01 ENST00000423795.1
cadherin-like and PC-esterase domain containing 1
chr20_-_33539655 0.01 ENST00000451957.2
glutathione synthetase
chr5_-_54988559 0.01 ENST00000502247.1
solute carrier family 38, member 9
chr19_+_16308711 0.01 ENST00000429941.2
ENST00000444449.2
ENST00000589822.1
adaptor-related protein complex 1, mu 1 subunit
chr6_+_42018614 0.01 ENST00000465926.1
ENST00000482432.1
TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa
chr5_-_54988448 0.01 ENST00000503817.1
ENST00000512595.1
solute carrier family 38, member 9
chr11_-_130786333 0.01 ENST00000533214.1
ENST00000528555.1
ENST00000530356.1
ENST00000539184.1
sorting nexin 19
chr1_+_241695424 0.01 ENST00000366558.3
ENST00000366559.4
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr14_-_24911448 0.01 ENST00000555355.1
ENST00000553343.1
ENST00000556523.1
ENST00000556249.1
ENST00000538105.2
ENST00000555225.1
short chain dehydrogenase/reductase family 39U, member 1
chr11_-_65626797 0.01 ENST00000525451.2
cofilin 1 (non-muscle)
chr11_-_102962929 0.01 ENST00000260247.5
DCN1, defective in cullin neddylation 1, domain containing 5
chr1_-_16539094 0.01 ENST00000270747.3
Rho guanine nucleotide exchange factor (GEF) 19
chr6_-_28806779 0.01 ENST00000457253.1
XXbac-BPG308K3.5
chr2_+_122513109 0.01 ENST00000389682.3
ENST00000536142.1
translin
chr4_-_54424366 0.01 ENST00000306888.2
ligand of numb-protein X 1, E3 ubiquitin protein ligase
chr11_-_65626753 0.01 ENST00000526975.1
ENST00000531413.1
cofilin 1 (non-muscle)
chr1_-_161039753 0.01 ENST00000368015.1
Rho GTPase activating protein 30
chr13_+_24825824 0.01 ENST00000434675.1
ENST00000494772.1
spermatogenesis associated 13
chr11_+_130029457 0.01 ENST00000278742.5
suppression of tumorigenicity 14 (colon carcinoma)
chr19_-_36001286 0.01 ENST00000602679.1
ENST00000492341.2
ENST00000472252.2
ENST00000602781.1
ENST00000402589.2
ENST00000458071.1
ENST00000436012.1
ENST00000443640.1
ENST00000450261.1
ENST00000467637.1
ENST00000480502.1
ENST00000474928.1
ENST00000414866.2
ENST00000392206.2
ENST00000488892.1
dermokine
chr2_-_74619152 0.01 ENST00000440727.1
ENST00000409240.1
dynactin 1
chr18_+_8717369 0.01 ENST00000359865.3
ENST00000400050.3
ENST00000306285.7
SOGA family member 2
chrX_-_15333736 0.01 ENST00000380470.3
ankyrin repeat and SOCS box containing 11
chr1_-_154928562 0.01 ENST00000368463.3
ENST00000539880.1
ENST00000542459.1
ENST00000368460.3
ENST00000368465.1
pre-B-cell leukemia homeobox interacting protein 1
chr1_+_40840320 0.01 ENST00000372708.1
small ArfGAP2
chr1_+_28764653 0.01 ENST00000373836.3
phosphatase and actin regulator 4
chr5_+_177631497 0.01 ENST00000358344.3
heterogeneous nuclear ribonucleoprotein A/B
chr1_+_174844645 0.01 ENST00000486220.1
RAB GTPase activating protein 1-like
chr1_-_26372602 0.01 ENST00000374278.3
ENST00000374276.3
solute carrier family 30 (zinc transporter), member 2
chr16_-_29415350 0.01 ENST00000524087.1
nuclear pore complex interacting protein family, member B11
chr9_-_113761720 0.01 ENST00000541779.1
ENST00000374430.2
lysophosphatidic acid receptor 1
chr16_-_66583701 0.01 ENST00000527800.1
ENST00000525974.1
ENST00000563369.2
thymidine kinase 2, mitochondrial
chr3_-_52002403 0.01 ENST00000490063.1
ENST00000468324.1
ENST00000497653.1
ENST00000484633.1
poly(rC) binding protein 4
chr2_-_160654745 0.01 ENST00000259053.4
ENST00000429078.2
CD302 molecule
chr6_+_151186554 0.01 ENST00000367321.3
ENST00000367307.4
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr16_-_69448 0.01 ENST00000326592.9
WAS protein family homolog 4 pseudogene
chr14_-_27066960 0.01 ENST00000539517.2
neuro-oncological ventral antigen 1
chr6_-_144416737 0.01 ENST00000367569.2
splicing factor 3b, subunit 5, 10kDa
chr7_+_99195677 0.01 ENST00000431679.1
GS1-259H13.2
chr10_+_60028818 0.01 ENST00000333926.5
CDGSH iron sulfur domain 1
chr17_-_71223839 0.01 ENST00000579872.1
ENST00000580032.1
family with sequence similarity 104, member A
chr11_-_102962874 0.01 ENST00000531543.1
DCN1, defective in cullin neddylation 1, domain containing 5
chr11_-_67275542 0.01 ENST00000531506.1
cyclin-dependent kinase 2 associated protein 2
chr4_+_22999152 0.01 ENST00000511453.1
RP11-412P11.1
chr1_+_243419306 0.01 ENST00000355875.4
ENST00000391846.1
ENST00000366541.3
ENST00000343783.6
serologically defined colon cancer antigen 8
chr19_-_36001113 0.01 ENST00000434389.1
dermokine
chr2_-_85637459 0.01 ENST00000409921.1
capping protein (actin filament), gelsolin-like
chr6_-_105307711 0.01 ENST00000519645.1
ENST00000262903.4
ENST00000369125.2
HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1
chr20_+_48884002 0.01 ENST00000425497.1
ENST00000445003.1
RP11-290F20.3
chr12_+_6603253 0.01 ENST00000382457.4
ENST00000545962.1
non-SMC condensin I complex, subunit D2
chr15_-_55657428 0.01 ENST00000568543.1
cell cycle progression 1
chr18_+_616711 0.01 ENST00000579494.1
clusterin-like 1 (retinal)
chr7_+_16700806 0.01 ENST00000446596.1
ENST00000438834.1
basic leucine zipper and W2 domains 2
chr9_+_91605778 0.01 ENST00000375851.2
ENST00000375850.3
ENST00000334490.5
chromosome 9 open reading frame 47
chr14_+_21458127 0.01 ENST00000382985.4
ENST00000556670.2
ENST00000553564.1
ENST00000554751.1
ENST00000554283.1
ENST00000555670.1
methyltransferase like 17
chr7_-_120498357 0.01 ENST00000415871.1
ENST00000222747.3
ENST00000430985.1
tetraspanin 12
chr18_+_616672 0.01 ENST00000338387.7
clusterin-like 1 (retinal)
chr16_-_21436459 0.01 ENST00000448012.2
ENST00000504841.2
ENST00000419180.2
nuclear pore complex interacting protein family, member B3
chr9_+_125132803 0.01 ENST00000540753.1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr17_-_4689649 0.01 ENST00000441199.2
ENST00000416307.2
vitelline membrane outer layer 1 homolog (chicken)
chr14_+_50234309 0.01 ENST00000298307.5
kelch domain containing 2
chr5_+_80256453 0.01 ENST00000265080.4
Ras protein-specific guanine nucleotide-releasing factor 2
chr3_-_69062790 0.01 ENST00000540955.1
ENST00000456376.1
EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
chr14_-_80697396 0.01 ENST00000557010.1
deiodinase, iodothyronine, type II
chr19_-_3761673 0.01 ENST00000316757.3
amyloid beta (A4) precursor protein-binding, family A, member 3
chr5_+_59783540 0.01 ENST00000515734.2
prostate androgen-regulated transcript 1 (non-protein coding)
chrX_-_109561294 0.00 ENST00000372059.2
ENST00000262844.5
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr3_+_11314099 0.00 ENST00000446450.2
ENST00000354956.5
ENST00000354449.3
ENST00000419112.1
autophagy related 7
chr9_-_35665165 0.00 ENST00000343259.3
ENST00000378387.3
Rho guanine nucleotide exchange factor (GEF) 39
chr2_-_106054952 0.00 ENST00000336660.5
ENST00000393352.3
ENST00000607522.1
four and a half LIM domains 2
chr14_-_89878369 0.00 ENST00000553840.1
ENST00000556916.1
forkhead box N3
chr22_+_39052632 0.00 ENST00000411557.1
ENST00000396811.2
ENST00000216029.3
ENST00000416285.1
chibby homolog 1 (Drosophila)
chr3_-_27410847 0.00 ENST00000429845.2
ENST00000341435.5
ENST00000435750.1
NIMA-related kinase 10
chr6_-_34393825 0.00 ENST00000605528.1
ENST00000326199.8
RPS10-NUDT3 readthrough
ribosomal protein S10
chr9_-_100684845 0.00 ENST00000375119.3
chromosome 9 open reading frame 156
chr15_+_58702742 0.00 ENST00000356113.6
ENST00000414170.3
lipase, hepatic
chr6_+_26158343 0.00 ENST00000377777.4
ENST00000289316.2
histone cluster 1, H2bd
chr15_-_61521495 0.00 ENST00000335670.6
RAR-related orphan receptor A
chr1_+_229440129 0.00 ENST00000366688.3
S-phase response (cyclin related)
chr9_+_116172958 0.00 ENST00000374165.1
chromosome 9 open reading frame 43
chr10_+_114133773 0.00 ENST00000354655.4
acyl-CoA synthetase long-chain family member 5
chr10_-_116418053 0.00 ENST00000277895.5
actin binding LIM protein 1
chr15_+_43425672 0.00 ENST00000260403.2
transmembrane protein 62
chr2_+_102721023 0.00 ENST00000409589.1
ENST00000409329.1
interleukin 1 receptor, type I
chr8_+_65492756 0.00 ENST00000321870.1
basic helix-loop-helix family, member e22
chr9_+_128509624 0.00 ENST00000342287.5
ENST00000373487.4
pre-B-cell leukemia homeobox 3
chr1_+_117910047 0.00 ENST00000356554.3
mannosidase, alpha, class 1A, member 2
chr15_-_43876702 0.00 ENST00000348806.6
diphosphoinositol pentakisphosphate kinase 1
chr19_-_42916499 0.00 ENST00000601189.1
ENST00000599211.1
lipase, hormone-sensitive
chr19_+_16308659 0.00 ENST00000590263.1
ENST00000590756.1
ENST00000541844.1
adaptor-related protein complex 1, mu 1 subunit
chr1_+_45805342 0.00 ENST00000372090.5
target of EGR1, member 1 (nuclear)
chr2_-_211090162 0.00 ENST00000233710.3
acyl-CoA dehydrogenase, long chain
chr2_+_109403193 0.00 ENST00000412964.2
ENST00000295124.4
coiled-coil domain containing 138
chr16_+_33204156 0.00 ENST00000398667.4
TP53 target 3C
chr1_-_151300160 0.00 ENST00000368874.4
phosphatidylinositol 4-kinase, catalytic, beta
chr21_-_43816052 0.00 ENST00000398405.1
transmembrane protease, serine 3
chr14_-_27066636 0.00 ENST00000267422.7
ENST00000344429.5
ENST00000574031.1
ENST00000465357.2
ENST00000547619.1
neuro-oncological ventral antigen 1
chr13_+_23755099 0.00 ENST00000537476.1
sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
chr16_-_21868978 0.00 ENST00000357370.5
ENST00000451409.1
ENST00000341400.7
ENST00000518761.4
nuclear pore complex interacting protein family, member B4
chr15_+_92006567 0.00 ENST00000554333.1
RP11-661P17.1
chr9_-_95298314 0.00 ENST00000344604.5
ENST00000375540.1
extracellular matrix protein 2, female organ and adipocyte specific
chr2_+_201936707 0.00 ENST00000433898.1
ENST00000454214.1
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa
chr3_-_45017609 0.00 ENST00000342790.4
ENST00000424952.2
ENST00000296127.3
ENST00000455235.1
zinc finger, DHHC-type containing 3

Network of associatons between targets according to the STRING database.

First level regulatory network of OTX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 GO:2000395 regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.0 0.0 GO:0042361 menaquinone catabolic process(GO:0042361) vitamin K catabolic process(GO:0042377)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.0 0.0 GO:0052871 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)