Project
A549 cells infected with IAV Analysis Results (GEO series: GSE147507)
Navigation
Downloads
Results for PATZ1_KLF4
Z-value: 4.61
Motif logo
Transcription factors associated with PATZ1_KLF4
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| PATZ1 | hg19_v2_chr22_-_31742218_31742350 | 0.99 | 1.4e-02 | Click! |
| KLF4 | hg19_v2_chr9_-_110251836_110251927 | 0.37 | 6.3e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr9_+_130922537 Show fit | 8.81 |
ENST00000372994.1
|
chromosome 9 open reading frame 16 |
|
| chr8_-_145691031 Show fit | 7.30 |
ENST00000424149.2
ENST00000530637.1 ENST00000306145.5 |
cysteine/histidine-rich 1 |
|
| chr19_-_1863567 Show fit | 6.77 |
ENST00000250916.4
|
Kruppel-like factor 16 |
|
| chr19_+_47778119 Show fit | 6.66 |
ENST00000552360.2
|
proline rich 24 |
|
| chr11_+_64073022 Show fit | 6.62 |
ENST00000406310.1
ENST00000000442.6 ENST00000539594.1 |
estrogen-related receptor alpha |
|
| chr19_+_6373482 Show fit | 6.52 |
ENST00000596657.1
|
alkB, alkylation repair homolog 7 (E. coli) |
|
| chr19_+_6373715 Show fit | 6.39 |
ENST00000599849.1
|
alkB, alkylation repair homolog 7 (E. coli) |
|
| chr14_-_21566731 Show fit | 6.30 |
ENST00000360947.3
|
zinc finger protein 219 |
|
| chr2_-_178129551 Show fit | 5.68 |
ENST00000430047.1
|
nuclear factor, erythroid 2-like 2 |
|
| chr14_+_105559784 Show fit | 5.61 |
ENST00000548104.1
|
RP11-44N21.1 |
Network of associatons between targets according to the STRING database.
First level regulatory network of PATZ1_KLF4
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.7 | 15.1 | GO:0006049 | UDP-N-acetylglucosamine catabolic process(GO:0006049) |
| 0.4 | 14.5 | GO:0050655 | dermatan sulfate proteoglycan metabolic process(GO:0050655) |
| 1.1 | 13.8 | GO:0018401 | peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) |
| 2.1 | 12.8 | GO:1902445 | regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445) |
| 0.3 | 12.0 | GO:0035428 | hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659) |
| 1.2 | 11.9 | GO:0002159 | desmosome assembly(GO:0002159) |
| 0.5 | 11.8 | GO:1901642 | nucleoside transmembrane transport(GO:1901642) |
| 0.1 | 11.5 | GO:0070125 | mitochondrial translational elongation(GO:0070125) |
| 0.6 | 11.3 | GO:0038203 | TORC2 signaling(GO:0038203) |
| 1.9 | 11.1 | GO:0010940 | positive regulation of necrotic cell death(GO:0010940) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 489.3 | GO:0016021 | integral component of membrane(GO:0016021) |
| 0.3 | 47.3 | GO:0043202 | lysosomal lumen(GO:0043202) |
| 0.1 | 45.0 | GO:0005759 | mitochondrial matrix(GO:0005759) |
| 0.3 | 20.9 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
| 0.2 | 20.2 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.2 | 16.5 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.5 | 16.4 | GO:0038201 | TOR complex(GO:0038201) |
| 0.3 | 13.3 | GO:0043034 | costamere(GO:0043034) |
| 0.3 | 12.4 | GO:0005779 | integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231) |
| 0.1 | 11.5 | GO:0031526 | brush border membrane(GO:0031526) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 22.4 | GO:0051213 | dioxygenase activity(GO:0051213) |
| 0.0 | 17.3 | GO:0005096 | GTPase activator activity(GO:0005096) |
| 1.7 | 15.1 | GO:0003827 | alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827) |
| 0.6 | 14.2 | GO:0045294 | alpha-catenin binding(GO:0045294) |
| 1.4 | 14.1 | GO:0019826 | oxygen sensor activity(GO:0019826) |
| 0.7 | 14.1 | GO:0055056 | D-glucose transmembrane transporter activity(GO:0055056) |
| 1.5 | 13.1 | GO:0004969 | histamine receptor activity(GO:0004969) |
| 0.2 | 13.0 | GO:0004879 | RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531) |
| 0.3 | 11.8 | GO:0003746 | translation elongation factor activity(GO:0003746) |
| 1.6 | 11.0 | GO:0008503 | benzodiazepine receptor activity(GO:0008503) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 26.3 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.2 | 21.8 | WNT SIGNALING | Genes related to Wnt-mediated signal transduction |
| 0.3 | 19.0 | PID RXR VDR PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.2 | 14.0 | NABA COLLAGENS | Genes encoding collagen proteins |
| 0.2 | 12.5 | PID HIF2PATHWAY | HIF-2-alpha transcription factor network |
| 0.1 | 11.5 | PID ECADHERIN STABILIZATION PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
| 0.1 | 11.2 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.1 | 9.6 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.4 | 8.8 | SA PROGRAMMED CELL DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
| 0.1 | 8.6 | PID CERAMIDE PATHWAY | Ceramide signaling pathway |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 25.2 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.7 | 22.8 | REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS | Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis |
| 0.4 | 21.2 | REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES | Genes involved in Transport of vitamins, nucleosides, and related molecules |
| 0.2 | 17.5 | REACTOME GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
| 0.6 | 15.0 | REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
| 0.2 | 14.3 | REACTOME METABOLISM OF VITAMINS AND COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
| 0.1 | 14.2 | REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
| 0.3 | 13.8 | REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION | Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation |
| 0.2 | 12.6 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.2 | 12.4 | REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION | Genes involved in Transport to the Golgi and subsequent modification |