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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for POU2F2_POU3F1

Z-value: 2.58

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Transcription factors associated with POU2F2_POU3F1

Gene Symbol Gene ID Gene Info
POU2F2
ENSG00000028277.16 POU class 2 homeobox 2
POU3F1
ENSG00000185668.5 POU class 3 homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
POU2F2hg19_v2_chr19_-_42636543_42636607-0.524.8e-01Click!

Activity profile of POU2F2_POU3F1 motif

Sorted Z-values of POU2F2_POU3F1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_26183958 5.63 ENST00000356530.3
HIST1H2BE
histone cluster 1, H2be
chr6_+_27114861 4.03 ENST00000377459.1
HIST1H2AH
histone cluster 1, H2ah
chr6_-_26033796 3.77 ENST00000259791.2
HIST1H2AB
histone cluster 1, H2ab
chr6_+_27782788 3.46 ENST00000359465.4
HIST1H2BM
histone cluster 1, H2bm
chr6_-_27860956 3.40 ENST00000359611.2
HIST1H2AM
histone cluster 1, H2am
chr6_-_26043885 3.40 ENST00000357905.2
HIST1H2BB
histone cluster 1, H2bb
chr1_+_228645796 3.35 ENST00000369160.2
HIST3H2BB
histone cluster 3, H2bb
chr6_-_27782548 2.86 ENST00000333151.3
HIST1H2AJ
histone cluster 1, H2aj
chr1_+_149822620 2.69 ENST00000369159.2
HIST2H2AA4
histone cluster 2, H2aa4
chr1_-_149783914 2.69 ENST00000369167.1
ENST00000427880.2
ENST00000545683.1
HIST2H2BF
histone cluster 2, H2bf
chr6_+_27861190 2.60 ENST00000303806.4
HIST1H2BO
histone cluster 1, H2bo
chr1_+_149858461 2.51 ENST00000331380.2
HIST2H2AC
histone cluster 2, H2ac
chr9_-_35658007 2.29 ENST00000602361.1
RMRP
RNA component of mitochondrial RNA processing endoribonuclease
chr6_+_26273144 2.09 ENST00000377733.2
HIST1H2BI
histone cluster 1, H2bi
chr1_-_228645556 1.90 ENST00000366695.2
HIST3H2A
histone cluster 3, H2a
chr17_+_19091325 1.82 ENST00000584923.1
SNORD3A
small nucleolar RNA, C/D box 3A
chr7_-_27153454 1.71 ENST00000522456.1
HOXA3
homeobox A3
chr1_-_149814478 1.66 ENST00000369161.3
HIST2H2AA3
histone cluster 2, H2aa3
chr6_-_26124138 1.64 ENST00000314332.5
ENST00000396984.1
HIST1H2BC
histone cluster 1, H2bc
chr6_+_31588478 1.61 ENST00000376007.4
ENST00000376033.2
PRRC2A
proline-rich coiled-coil 2A
chr19_-_44124019 1.49 ENST00000300811.3
ZNF428
zinc finger protein 428
chr17_-_19651598 1.47 ENST00000570414.1
ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chr1_+_201979743 1.38 ENST00000446188.1
ELF3
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr12_+_7052974 1.34 ENST00000544681.1
ENST00000537087.1
C12orf57
chromosome 12 open reading frame 57
chr6_+_26251835 1.27 ENST00000356350.2
HIST1H2BH
histone cluster 1, H2bh
chr6_-_27775694 1.25 ENST00000377401.2
HIST1H2BL
histone cluster 1, H2bl
chr6_-_26216872 1.20 ENST00000244601.3
HIST1H2BG
histone cluster 1, H2bg
chr12_+_122064398 1.14 ENST00000330079.7
ORAI1
ORAI calcium release-activated calcium modulator 1
chr6_-_27100529 1.07 ENST00000607124.1
ENST00000339812.2
ENST00000541790.1
HIST1H2BJ
histone cluster 1, H2bj
chr6_+_27775899 1.02 ENST00000358739.3
HIST1H2AI
histone cluster 1, H2ai
chr19_+_41305330 0.99 ENST00000593972.1
EGLN2
egl-9 family hypoxia-inducible factor 2
chr2_-_207082748 0.99 ENST00000407325.2
ENST00000411719.1
GPR1
G protein-coupled receptor 1
chr19_+_56111680 0.97 ENST00000301073.3
ZNF524
zinc finger protein 524
chr1_-_149859466 0.97 ENST00000331128.3
HIST2H2AB
histone cluster 2, H2ab
chr7_-_44122063 0.94 ENST00000335195.6
ENST00000395831.3
ENST00000414235.1
ENST00000452049.1
ENST00000242248.5
POLM
polymerase (DNA directed), mu
chr2_-_239148599 0.93 ENST00000409182.1
ENST00000409002.3
ENST00000450098.1
ENST00000409356.1
ENST00000409160.3
ENST00000409574.1
ENST00000272937.5
HES6
hes family bHLH transcription factor 6
chr8_-_33370607 0.93 ENST00000360742.5
ENST00000523305.1
TTI2
TELO2 interacting protein 2
chr12_-_11214893 0.90 ENST00000533467.1
TAS2R46
taste receptor, type 2, member 46
chr17_-_19015945 0.89 ENST00000573866.2
SNORD3D
small nucleolar RNA, C/D box 3D
chr19_+_17337027 0.85 ENST00000601529.1
ENST00000600232.1
OCEL1
occludin/ELL domain containing 1
chr9_+_136325089 0.85 ENST00000291722.7
ENST00000316948.4
ENST00000540581.1
CACFD1
calcium channel flower domain containing 1
chr6_+_37137939 0.84 ENST00000373509.5
PIM1
pim-1 oncogene
chr17_-_7307358 0.82 ENST00000576017.1
ENST00000302422.3
ENST00000535512.1
TMEM256
TMEM256-PLSCR3
transmembrane protein 256
TMEM256-PLSCR3 readthrough (NMD candidate)
chr19_-_18392422 0.79 ENST00000252818.3
JUND
jun D proto-oncogene
chr6_+_27100811 0.78 ENST00000359193.2
HIST1H2AG
histone cluster 1, H2ag
chr19_+_50169081 0.76 ENST00000246784.3
BCL2L12
BCL2-like 12 (proline rich)
chr2_+_90192768 0.74 ENST00000390275.2
IGKV1D-13
immunoglobulin kappa variable 1D-13
chr17_-_19651654 0.71 ENST00000395555.3
ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chr17_-_19651668 0.70 ENST00000494157.2
ENST00000225740.6
ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chr5_+_2752258 0.68 ENST00000334000.3
C5orf38
chromosome 5 open reading frame 38
chr16_+_3019309 0.68 ENST00000576565.1
PAQR4
progestin and adipoQ receptor family member IV
chr18_-_52989525 0.67 ENST00000457482.3
TCF4
transcription factor 4
chr1_+_225600404 0.65 ENST00000366845.2
AC092811.1
AC092811.1
chr19_-_47291843 0.64 ENST00000542575.2
SLC1A5
solute carrier family 1 (neutral amino acid transporter), member 5
chr16_-_30107491 0.64 ENST00000566134.1
ENST00000565110.1
ENST00000398841.1
ENST00000398838.4
YPEL3
yippee-like 3 (Drosophila)
chrX_+_12993202 0.64 ENST00000451311.2
ENST00000380636.1
TMSB4X
thymosin beta 4, X-linked
chr16_+_3019246 0.63 ENST00000318782.8
ENST00000293978.8
PAQR4
progestin and adipoQ receptor family member IV
chr16_+_3019552 0.63 ENST00000572687.1
PAQR4
progestin and adipoQ receptor family member IV
chr17_+_72426891 0.63 ENST00000392627.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr6_+_26124373 0.62 ENST00000377791.2
ENST00000602637.1
HIST1H2AC
histone cluster 1, H2ac
chr19_+_17858509 0.62 ENST00000594202.1
ENST00000252771.7
ENST00000389133.4
FCHO1
FCH domain only 1
chr1_+_32538492 0.61 ENST00000336294.5
TMEM39B
transmembrane protein 39B
chr2_+_220143989 0.61 ENST00000336576.5
DNAJB2
DnaJ (Hsp40) homolog, subfamily B, member 2
chr14_-_107283278 0.60 ENST00000390639.2
IGHV7-81
immunoglobulin heavy variable 7-81 (non-functional)
chr14_-_23446003 0.60 ENST00000553911.1
AJUBA
ajuba LIM protein
chr19_+_42788172 0.60 ENST00000160740.3
CIC
capicua transcriptional repressor
chr11_-_62359027 0.59 ENST00000494385.1
ENST00000308436.7
TUT1
terminal uridylyl transferase 1, U6 snRNA-specific
chr12_+_122064673 0.59 ENST00000537188.1
ORAI1
ORAI calcium release-activated calcium modulator 1
chr19_+_50169216 0.58 ENST00000594157.1
ENST00000600947.1
ENST00000598306.1
BCL2L12
BCL2-like 12 (proline rich)
chr6_+_43139037 0.58 ENST00000265354.4
SRF
serum response factor (c-fos serum response element-binding transcription factor)
chr11_+_74699942 0.58 ENST00000526068.1
ENST00000532963.1
ENST00000531619.1
ENST00000534628.1
ENST00000545272.1
NEU3
sialidase 3 (membrane sialidase)
chrX_-_48776292 0.58 ENST00000376509.4
PIM2
pim-2 oncogene
chr19_-_40931891 0.58 ENST00000357949.4
SERTAD1
SERTA domain containing 1
chr19_+_17337007 0.57 ENST00000215061.4
OCEL1
occludin/ELL domain containing 1
chr2_-_219906220 0.55 ENST00000458526.1
ENST00000409865.3
ENST00000410037.1
ENST00000457968.1
ENST00000436631.1
ENST00000341552.5
ENST00000441968.1
ENST00000295729.2
CCDC108
coiled-coil domain containing 108
chr22_+_43011247 0.54 ENST00000602478.1
RNU12
RNA, U12 small nuclear
chr11_-_62369291 0.53 ENST00000278823.2
MTA2
metastasis associated 1 family, member 2
chr11_+_110225855 0.53 ENST00000526605.1
ENST00000526703.1
RP11-347E10.1
RP11-347E10.1
chr6_+_151358048 0.52 ENST00000450635.1
MTHFD1L
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr19_-_44123734 0.51 ENST00000598676.1
ZNF428
zinc finger protein 428
chr2_+_220144052 0.51 ENST00000425450.1
ENST00000392086.4
ENST00000421532.1
DNAJB2
DnaJ (Hsp40) homolog, subfamily B, member 2
chr19_-_46088068 0.51 ENST00000263275.4
ENST00000323060.3
OPA3
optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
chr15_+_67458357 0.51 ENST00000537194.2
SMAD3
SMAD family member 3
chr2_+_90198535 0.50 ENST00000390276.2
IGKV1D-12
immunoglobulin kappa variable 1D-12
chrX_-_55020511 0.50 ENST00000375006.3
ENST00000374992.2
PFKFB1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr17_+_73521763 0.50 ENST00000167462.5
ENST00000375227.4
ENST00000392550.3
ENST00000578363.1
ENST00000579392.1
LLGL2
lethal giant larvae homolog 2 (Drosophila)
chr3_-_87040259 0.50 ENST00000383698.3
VGLL3
vestigial like 3 (Drosophila)
chr9_-_140196703 0.48 ENST00000356628.2
NRARP
NOTCH-regulated ankyrin repeat protein
chr15_-_41166414 0.48 ENST00000220507.4
RHOV
ras homolog family member V
chr11_+_74699703 0.48 ENST00000529024.1
ENST00000544263.1
NEU3
sialidase 3 (membrane sialidase)
chr12_+_72080253 0.48 ENST00000549735.1
TMEM19
transmembrane protein 19
chrX_+_12993336 0.47 ENST00000380635.1
TMSB4X
thymosin beta 4, X-linked
chr1_-_8000872 0.47 ENST00000377507.3
TNFRSF9
tumor necrosis factor receptor superfamily, member 9
chr2_+_66918558 0.47 ENST00000435389.1
ENST00000428590.1
ENST00000412944.1
AC007392.3
AC007392.3
chr19_+_39903185 0.46 ENST00000409794.3
PLEKHG2
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr19_-_40791302 0.46 ENST00000392038.2
ENST00000578123.1
AKT2
v-akt murine thymoma viral oncogene homolog 2
chr6_-_33679452 0.46 ENST00000374231.4
ENST00000607484.1
ENST00000374214.3
UQCC2
ubiquinol-cytochrome c reductase complex assembly factor 2
chr19_-_50168962 0.46 ENST00000599223.1
ENST00000593922.1
ENST00000600022.1
ENST00000596765.1
ENST00000599144.1
ENST00000596822.1
ENST00000598108.1
ENST00000601373.1
ENST00000595034.1
ENST00000601291.1
IRF3
interferon regulatory factor 3
chr20_+_34556488 0.46 ENST00000373973.3
ENST00000349339.1
ENST00000538900.1
CNBD2
cyclic nucleotide binding domain containing 2
chr16_-_75285380 0.46 ENST00000393420.6
ENST00000162330.5
BCAR1
breast cancer anti-estrogen resistance 1
chr10_+_24528108 0.46 ENST00000438429.1
KIAA1217
KIAA1217
chr14_-_23446021 0.45 ENST00000553592.1
AJUBA
ajuba LIM protein
chr12_-_7245018 0.44 ENST00000543835.1
ENST00000535233.2
C1R
complement component 1, r subcomponent
chr1_+_167298281 0.44 ENST00000367862.5
POU2F1
POU class 2 homeobox 1
chr19_-_1132207 0.44 ENST00000438103.2
SBNO2
strawberry notch homolog 2 (Drosophila)
chr1_+_59775752 0.43 ENST00000371212.1
FGGY
FGGY carbohydrate kinase domain containing
chr19_-_8373173 0.43 ENST00000537716.2
ENST00000301458.5
CD320
CD320 molecule
chr19_+_11466167 0.43 ENST00000591608.1
DKFZP761J1410
Lipid phosphate phosphatase-related protein type 2
chr14_+_103573853 0.42 ENST00000560304.1
EXOC3L4
exocyst complex component 3-like 4
chr17_-_73127778 0.42 ENST00000578407.1
NT5C
5', 3'-nucleotidase, cytosolic
chr11_+_64085560 0.41 ENST00000265462.4
ENST00000352435.4
ENST00000347941.4
PRDX5
peroxiredoxin 5
chr9_+_136325149 0.41 ENST00000542192.1
CACFD1
calcium channel flower domain containing 1
chr19_+_17337406 0.41 ENST00000597836.1
OCEL1
occludin/ELL domain containing 1
chr12_-_56224546 0.40 ENST00000357606.3
ENST00000547445.1
DNAJC14
DnaJ (Hsp40) homolog, subfamily C, member 14
chr19_-_45982076 0.40 ENST00000423698.2
ERCC1
excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr17_+_40118773 0.40 ENST00000472031.1
CNP
2',3'-cyclic nucleotide 3' phosphodiesterase
chr16_-_19897455 0.40 ENST00000568214.1
ENST00000569479.1
GPRC5B
G protein-coupled receptor, family C, group 5, member B
chr1_+_201979645 0.39 ENST00000367284.5
ENST00000367283.3
ELF3
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr17_+_14204389 0.39 ENST00000360954.2
HS3ST3B1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chr18_-_46784778 0.39 ENST00000582399.1
DYM
dymeclin
chr2_-_37068530 0.38 ENST00000593798.1
AC007382.1
Uncharacterized protein
chr2_+_145780739 0.38 ENST00000597173.1
ENST00000602108.1
ENST00000420472.1
TEX41
testis expressed 41 (non-protein coding)
chr12_+_14927270 0.37 ENST00000544848.1
H2AFJ
H2A histone family, member J
chr2_-_158182105 0.37 ENST00000409925.1
ERMN
ermin, ERM-like protein
chr5_+_2752334 0.37 ENST00000505778.1
ENST00000515640.1
ENST00000397835.4
C5orf38
chromosome 5 open reading frame 38
chr6_-_52628271 0.37 ENST00000493422.1
GSTA2
glutathione S-transferase alpha 2
chr16_-_73082274 0.37 ENST00000268489.5
ZFHX3
zinc finger homeobox 3
chr6_+_166945369 0.37 ENST00000598601.1
Z98049.1
CDNA FLJ25492 fis, clone CBR01389; Uncharacterized protein
chr16_+_2198604 0.36 ENST00000210187.6
RAB26
RAB26, member RAS oncogene family
chr1_-_23886285 0.36 ENST00000374561.5
ID3
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr1_-_149858227 0.35 ENST00000369155.2
HIST2H2BE
histone cluster 2, H2be
chr5_-_88120151 0.35 ENST00000506716.1
MEF2C
myocyte enhancer factor 2C
chr11_-_62358972 0.35 ENST00000278279.3
TUT1
terminal uridylyl transferase 1, U6 snRNA-specific
chr17_+_40118805 0.35 ENST00000591072.1
ENST00000587679.1
ENST00000393888.1
ENST00000441615.2
CNP
2',3'-cyclic nucleotide 3' phosphodiesterase
chr1_+_32538520 0.35 ENST00000438825.1
ENST00000456834.2
ENST00000373634.4
ENST00000427288.1
TMEM39B
transmembrane protein 39B
chr16_-_11730213 0.35 ENST00000576334.1
ENST00000574848.1
LITAF
lipopolysaccharide-induced TNF factor
chr6_-_10415218 0.35 ENST00000466073.1
ENST00000498450.1
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr5_-_141030943 0.35 ENST00000522783.1
ENST00000519800.1
ENST00000435817.2
FCHSD1
FCH and double SH3 domains 1
chr16_-_88752889 0.35 ENST00000332281.5
SNAI3
snail family zinc finger 3
chr1_-_6052463 0.34 ENST00000378156.4
NPHP4
nephronophthisis 4
chr11_-_75917569 0.34 ENST00000322563.3
WNT11
wingless-type MMTV integration site family, member 11
chr12_-_100656134 0.34 ENST00000548313.1
DEPDC4
DEP domain containing 4
chr17_-_73127826 0.34 ENST00000582170.1
ENST00000245552.2
NT5C
5', 3'-nucleotidase, cytosolic
chr12_+_132312931 0.34 ENST00000360564.1
ENST00000545671.1
ENST00000545790.1
MMP17
matrix metallopeptidase 17 (membrane-inserted)
chr12_-_11150474 0.33 ENST00000538986.1
TAS2R20
taste receptor, type 2, member 20
chr3_-_149293990 0.32 ENST00000472417.1
WWTR1
WW domain containing transcription regulator 1
chr19_-_40562063 0.32 ENST00000598845.1
ENST00000593605.1
ENST00000221355.6
ENST00000434248.1
ZNF780B
zinc finger protein 780B
chr18_-_53089723 0.31 ENST00000561992.1
ENST00000562512.2
TCF4
transcription factor 4
chr19_-_1021113 0.31 ENST00000333175.5
ENST00000356663.3
TMEM259
transmembrane protein 259
chr6_-_52668605 0.31 ENST00000334575.5
GSTA1
glutathione S-transferase alpha 1
chr19_-_41903161 0.30 ENST00000602129.1
ENST00000593771.1
ENST00000596905.1
ENST00000221233.4
EXOSC5
exosome component 5
chr2_-_158182322 0.30 ENST00000420719.2
ENST00000409216.1
ERMN
ermin, ERM-like protein
chr17_+_40118759 0.30 ENST00000393892.3
CNP
2',3'-cyclic nucleotide 3' phosphodiesterase
chr19_-_893200 0.29 ENST00000269814.4
ENST00000395808.3
ENST00000312090.6
ENST00000325464.1
MED16
mediator complex subunit 16
chr17_-_46682321 0.29 ENST00000225648.3
ENST00000484302.2
HOXB6
homeobox B6
chr10_-_10504285 0.29 ENST00000602311.1
RP11-271F18.4
RP11-271F18.4
chrX_-_106960285 0.28 ENST00000503515.1
ENST00000372397.2
TSC22D3
TSC22 domain family, member 3
chr19_+_17337473 0.27 ENST00000598068.1
OCEL1
occludin/ELL domain containing 1
chr2_+_47922958 0.27 ENST00000606499.1
MSH6
mutS homolog 6
chr2_-_61108449 0.27 ENST00000439412.1
ENST00000452343.1
AC010733.4
AC010733.4
chr12_-_7245080 0.27 ENST00000541042.1
ENST00000540242.1
C1R
complement component 1, r subcomponent
chr22_-_17640110 0.27 ENST00000399852.3
ENST00000336737.4
CECR5
cat eye syndrome chromosome region, candidate 5
chr17_+_38497640 0.26 ENST00000394086.3
RARA
retinoic acid receptor, alpha
chr20_+_33292068 0.26 ENST00000374810.3
ENST00000374809.2
ENST00000451665.1
TP53INP2
tumor protein p53 inducible nuclear protein 2
chr14_-_68283291 0.26 ENST00000555452.1
ENST00000347230.4
ZFYVE26
zinc finger, FYVE domain containing 26
chr19_-_50169064 0.25 ENST00000593337.1
ENST00000598808.1
ENST00000600453.1
ENST00000593818.1
ENST00000597198.1
ENST00000601809.1
ENST00000377139.3
IRF3
interferon regulatory factor 3
chr5_+_140593509 0.25 ENST00000341948.4
PCDHB13
protocadherin beta 13
chr18_-_53089538 0.25 ENST00000566777.1
TCF4
transcription factor 4
chr12_+_7053172 0.23 ENST00000229281.5
C12orf57
chromosome 12 open reading frame 57
chr7_+_27282319 0.23 ENST00000222761.3
EVX1
even-skipped homeobox 1
chr20_+_816695 0.23 ENST00000246100.3
FAM110A
family with sequence similarity 110, member A
chr19_-_3971050 0.23 ENST00000545797.2
ENST00000596311.1
DAPK3
death-associated protein kinase 3
chr1_-_117021430 0.23 ENST00000423907.1
ENST00000434879.1
ENST00000443219.1
RP4-655J12.4
RP4-655J12.4
chr1_+_6052700 0.23 ENST00000378092.1
ENST00000445501.1
KCNAB2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr18_-_52989217 0.23 ENST00000570287.2
TCF4
transcription factor 4
chr17_+_43213004 0.23 ENST00000586346.1
ENST00000398322.3
ENST00000592162.1
ENST00000376955.4
ENST00000321854.8
ACBD4
acyl-CoA binding domain containing 4
chr19_+_11466062 0.22 ENST00000251473.5
ENST00000591329.1
ENST00000586380.1
DKFZP761J1410
Lipid phosphate phosphatase-related protein type 2
chr6_+_155538093 0.22 ENST00000462408.2
TIAM2
T-cell lymphoma invasion and metastasis 2
chr20_-_39995467 0.22 ENST00000332312.3
EMILIN3
elastin microfibril interfacer 3
chr19_+_19144384 0.22 ENST00000392335.2
ENST00000535612.1
ENST00000537263.1
ENST00000540707.1
ENST00000541725.1
ENST00000269932.6
ENST00000546344.1
ENST00000540792.1
ENST00000536098.1
ENST00000541898.1
ENST00000543877.1
ARMC6
armadillo repeat containing 6
chr15_-_89456630 0.22 ENST00000268150.8
MFGE8
milk fat globule-EGF factor 8 protein
chr17_-_70417365 0.21 ENST00000580948.1
LINC00511
long intergenic non-protein coding RNA 511
chr17_+_42925270 0.21 ENST00000253410.2
ENST00000587021.1
HIGD1B
HIG1 hypoxia inducible domain family, member 1B
chr6_+_26158343 0.21 ENST00000377777.4
ENST00000289316.2
HIST1H2BD
histone cluster 1, H2bd
chr12_-_57328187 0.21 ENST00000293502.1
SDR9C7
short chain dehydrogenase/reductase family 9C, member 7
chr22_-_24096562 0.21 ENST00000398465.3
VPREB3
pre-B lymphocyte 3
chr11_-_34379546 0.21 ENST00000435224.2
ABTB2
ankyrin repeat and BTB (POZ) domain containing 2
chr17_-_3794021 0.20 ENST00000381769.2
CAMKK1
calcium/calmodulin-dependent protein kinase kinase 1, alpha
chr16_-_74808710 0.20 ENST00000219368.3
ENST00000544337.1
FA2H
fatty acid 2-hydroxylase
chr2_-_166930131 0.20 ENST00000303395.4
ENST00000409050.1
ENST00000423058.2
ENST00000375405.3
SCN1A
sodium channel, voltage-gated, type I, alpha subunit
chr14_-_107219365 0.20 ENST00000424969.2
IGHV3-74
immunoglobulin heavy variable 3-74
chr15_+_91478493 0.20 ENST00000418476.2
UNC45A
unc-45 homolog A (C. elegans)
chr4_-_99578789 0.20 ENST00000511651.1
ENST00000505184.1
TSPAN5
tetraspanin 5
chr14_-_51297360 0.20 ENST00000496749.1
NIN
ninein (GSK3B interacting protein)
chr15_-_64995399 0.20 ENST00000559753.1
ENST00000560258.2
ENST00000559912.2
ENST00000326005.6
OAZ2
ornithine decarboxylase antizyme 2
chr3_-_178969403 0.19 ENST00000314235.5
ENST00000392685.2
KCNMB3
potassium large conductance calcium-activated channel, subfamily M beta member 3
chr6_+_10585979 0.19 ENST00000265012.4
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr21_-_36260980 0.19 ENST00000344691.4
ENST00000358356.5
RUNX1
runt-related transcription factor 1
chr6_+_143999185 0.19 ENST00000542769.1
ENST00000397980.3
PHACTR2
phosphatase and actin regulator 2
chr7_-_27183263 0.19 ENST00000222726.3
HOXA5
homeobox A5

Network of associatons between targets according to the STRING database.

First level regulatory network of POU2F2_POU3F1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.7 GO:0002227 innate immune response in mucosa(GO:0002227)
0.3 1.5 GO:0036343 psychomotor behavior(GO:0036343)
0.2 1.1 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.2 1.7 GO:0010159 specification of organ position(GO:0010159)
0.2 0.6 GO:0061145 bronchus cartilage development(GO:0060532) lung smooth muscle development(GO:0061145)
0.2 0.6 GO:1903803 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.2 1.1 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.1 19.6 GO:0006342 chromatin silencing(GO:0006342)
0.1 0.4 GO:0031296 B cell costimulation(GO:0031296)
0.1 18.2 GO:0006334 nucleosome assembly(GO:0006334)
0.1 1.8 GO:0060056 mammary gland involution(GO:0060056)
0.1 0.5 GO:2001183 negative regulation of interleukin-12 secretion(GO:2001183)
0.1 0.3 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.1 0.4 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.1 1.1 GO:0006689 ganglioside catabolic process(GO:0006689)
0.1 0.5 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.1 0.4 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 1.7 GO:0002115 store-operated calcium entry(GO:0002115)
0.1 0.3 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.1 0.7 GO:0000710 meiotic mismatch repair(GO:0000710)
0.1 1.3 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.1 0.4 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 0.2 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.1 0.8 GO:0070561 vitamin D receptor signaling pathway(GO:0070561)
0.1 0.5 GO:0071486 cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.1 0.5 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 0.5 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.1 0.4 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 0.4 GO:2000111 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185) positive regulation of macrophage apoptotic process(GO:2000111)
0.1 0.4 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.1 0.8 GO:0071888 macrophage apoptotic process(GO:0071888)
0.1 0.8 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.1 0.3 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.1 0.9 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.1 0.5 GO:0014807 regulation of somitogenesis(GO:0014807)
0.1 0.6 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.1 0.2 GO:0072428 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) negative regulation of mitotic cell cycle DNA replication(GO:1903464) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1 0.3 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.1 0.2 GO:0060278 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.0 0.8 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.2 GO:0060535 trachea cartilage morphogenesis(GO:0060535)
0.0 0.5 GO:0097033 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.2 GO:0021623 optic cup structural organization(GO:0003409) oculomotor nerve morphogenesis(GO:0021622) oculomotor nerve formation(GO:0021623)
0.0 0.2 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.1 GO:0002309 T cell proliferation involved in immune response(GO:0002309)
0.0 1.0 GO:1900037 regulation of cellular response to hypoxia(GO:1900037)
0.0 0.1 GO:0060018 astrocyte fate commitment(GO:0060018)
0.0 0.2 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.0 0.1 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.0 0.2 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.4 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.3 GO:0070235 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.3 GO:0042756 drinking behavior(GO:0042756)
0.0 0.7 GO:0009223 pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.0 0.4 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.2 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.8 GO:0002076 osteoblast development(GO:0002076)
0.0 0.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.4 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.4 GO:0051601 exocyst localization(GO:0051601)
0.0 0.1 GO:0051464 positive regulation of cortisol secretion(GO:0051464) positive regulation of glucocorticoid secretion(GO:2000851)
0.0 0.7 GO:1901685 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.3 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.0 0.2 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.2 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.0 0.3 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.4 GO:0030903 notochord development(GO:0030903)
0.0 0.1 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.2 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.0 0.2 GO:0031033 myosin filament organization(GO:0031033)
0.0 1.0 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.6 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.0 GO:0046619 optic placode formation(GO:0001743) optic placode formation involved in camera-type eye formation(GO:0046619)
0.0 2.2 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.0 0.3 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.5 GO:0035729 cellular response to hepatocyte growth factor stimulus(GO:0035729)
0.0 0.0 GO:0032241 positive regulation of nucleobase-containing compound transport(GO:0032241) regulation of nucleoside transport(GO:0032242)
0.0 0.1 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 0.5 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.5 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.1 GO:0007402 ganglion mother cell fate determination(GO:0007402)
0.0 0.1 GO:0070141 response to UV-A(GO:0070141)
0.0 0.1 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.1 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
0.0 0.1 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.0 0.1 GO:2000690 regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.0 0.4 GO:1904294 positive regulation of ERAD pathway(GO:1904294)
0.0 0.2 GO:0005513 detection of calcium ion(GO:0005513)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 40.4 GO:0000786 nucleosome(GO:0000786)
0.1 0.8 GO:0035976 AP1 complex(GO:0035976)
0.1 1.0 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.1 0.4 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.1 0.3 GO:0032301 MutSalpha complex(GO:0032301)
0.1 0.2 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.0 0.2 GO:1990031 pinceau fiber(GO:1990031)
0.0 0.7 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.8 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.3 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559) cytoplasmic side of late endosome membrane(GO:0098560)
0.0 0.2 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.3 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.1 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.3 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)
0.0 0.3 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.1 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 0.5 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.1 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 1.4 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.4 GO:0000145 exocyst(GO:0000145)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.5 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.3 1.0 GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113)
0.2 1.1 GO:0052795 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.2 0.9 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.1 0.4 GO:0019150 D-ribulokinase activity(GO:0019150)
0.1 0.4 GO:0015235 cobalamin transporter activity(GO:0015235)
0.1 1.7 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 1.2 GO:0019826 oxygen sensor activity(GO:0019826)
0.1 0.6 GO:0010736 serum response element binding(GO:0010736)
0.1 0.5 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.1 0.5 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.1 1.7 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 1.1 GO:0042923 neuropeptide binding(GO:0042923)
0.1 0.6 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.1 2.1 GO:0071837 HMG box domain binding(GO:0071837)
0.1 0.3 GO:0030375 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.1 0.5 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 0.3 GO:0032143 single thymine insertion binding(GO:0032143)
0.1 1.0 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 0.4 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.1 38.3 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.4 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.4 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.2 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.1 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.7 GO:0019103 pyrimidine nucleotide binding(GO:0019103)
0.0 0.6 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.8 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.3 GO:0043426 MRF binding(GO:0043426)
0.0 0.2 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.4 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.3 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.9 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.8 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.2 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 1.0 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.2 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.4 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.2 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 1.1 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.8 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.0 GO:1904713 beta-catenin destruction complex binding(GO:1904713)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0004556 alpha-amylase activity(GO:0004556)
0.0 0.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.5 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 1.3 GO:0002039 p53 binding(GO:0002039)
0.0 0.5 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.1 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.1 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.1 GO:0030551 cyclic nucleotide binding(GO:0030551)
0.0 0.3 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.2 GO:0004745 retinol dehydrogenase activity(GO:0004745)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.5 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.8 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.5 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.5 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.6 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.5 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 1.8 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 41.3 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.2 1.7 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.7 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.5 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.8 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 2.1 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.3 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.2 REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS Genes involved in Post NMDA receptor activation events
0.0 0.4 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.8 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.3 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 1.1 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.7 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.2 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.0 0.7 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.5 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.3 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.4 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0 0.4 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.6 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane