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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for POU5F1_POU2F3

Z-value: 1.58

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Transcription factors associated with POU5F1_POU2F3

Gene Symbol Gene ID Gene Info
POU5F1
ENSG00000204531.11 POU class 5 homeobox 1
POU2F3
ENSG00000137709.5 POU class 2 homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
POU2F3hg19_v2_chr11_+_120110863_120110908-0.336.7e-01Click!
POU5F1hg19_v2_chr6_-_31138439_311384750.118.9e-01Click!

Activity profile of POU5F1_POU2F3 motif

Sorted Z-values of POU5F1_POU2F3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_26183958 2.70 ENST00000356530.3
HIST1H2BE
histone cluster 1, H2be
chr1_+_228645796 2.33 ENST00000369160.2
HIST3H2BB
histone cluster 3, H2bb
chr6_+_27782788 1.79 ENST00000359465.4
HIST1H2BM
histone cluster 1, H2bm
chr1_-_149783914 1.42 ENST00000369167.1
ENST00000427880.2
ENST00000545683.1
HIST2H2BF
histone cluster 2, H2bf
chr6_+_27114861 1.39 ENST00000377459.1
HIST1H2AH
histone cluster 1, H2ah
chr20_+_34556488 1.26 ENST00000373973.3
ENST00000349339.1
ENST00000538900.1
CNBD2
cyclic nucleotide binding domain containing 2
chr9_-_35658007 1.24 ENST00000602361.1
RMRP
RNA component of mitochondrial RNA processing endoribonuclease
chr10_-_10504285 1.20 ENST00000602311.1
RP11-271F18.4
RP11-271F18.4
chr9_-_117160738 1.17 ENST00000448674.1
RP11-9M16.2
RP11-9M16.2
chr6_-_26033796 1.13 ENST00000259791.2
HIST1H2AB
histone cluster 1, H2ab
chr6_-_27782548 1.05 ENST00000333151.3
HIST1H2AJ
histone cluster 1, H2aj
chr9_+_132099158 1.00 ENST00000444125.1
RP11-65J3.1
RP11-65J3.1
chr6_-_26043885 0.99 ENST00000357905.2
HIST1H2BB
histone cluster 1, H2bb
chr2_-_61108449 0.97 ENST00000439412.1
ENST00000452343.1
AC010733.4
AC010733.4
chr6_-_26216872 0.93 ENST00000244601.3
HIST1H2BG
histone cluster 1, H2bg
chr1_+_149858461 0.88 ENST00000331380.2
HIST2H2AC
histone cluster 2, H2ac
chr6_+_26273144 0.87 ENST00000377733.2
HIST1H2BI
histone cluster 1, H2bi
chr2_+_90192768 0.85 ENST00000390275.2
IGKV1D-13
immunoglobulin kappa variable 1D-13
chr6_-_26032288 0.84 ENST00000244661.2
HIST1H3B
histone cluster 1, H3b
chr6_-_26124138 0.80 ENST00000314332.5
ENST00000396984.1
HIST1H2BC
histone cluster 1, H2bc
chr4_+_124571409 0.73 ENST00000514823.1
ENST00000511919.1
ENST00000508111.1
RP11-93L9.1
long intergenic non-protein coding RNA 1091
chr22_+_43011247 0.72 ENST00000602478.1
RNU12
RNA, U12 small nuclear
chr6_-_27860956 0.67 ENST00000359611.2
HIST1H2AM
histone cluster 1, H2am
chr2_+_90198535 0.66 ENST00000390276.2
IGKV1D-12
immunoglobulin kappa variable 1D-12
chrX_-_55020511 0.63 ENST00000375006.3
ENST00000374992.2
PFKFB1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr2_+_66918558 0.60 ENST00000435389.1
ENST00000428590.1
ENST00000412944.1
AC007392.3
AC007392.3
chr17_-_19015945 0.60 ENST00000573866.2
SNORD3D
small nucleolar RNA, C/D box 3D
chr19_+_52873166 0.56 ENST00000424032.2
ENST00000600321.1
ENST00000344085.5
ENST00000597976.1
ENST00000422689.2
ZNF880
zinc finger protein 880
chr8_+_39759794 0.55 ENST00000518804.1
ENST00000519154.1
ENST00000522495.1
ENST00000522840.1
IDO1
indoleamine 2,3-dioxygenase 1
chr22_-_24096562 0.51 ENST00000398465.3
VPREB3
pre-B lymphocyte 3
chr1_-_149859466 0.50 ENST00000331128.3
HIST2H2AB
histone cluster 2, H2ab
chr17_+_19091325 0.49 ENST00000584923.1
SNORD3A
small nucleolar RNA, C/D box 3A
chr15_-_78526855 0.48 ENST00000541759.1
ENST00000558130.1
ACSBG1
acyl-CoA synthetase bubblegum family member 1
chr18_-_46784778 0.47 ENST00000582399.1
DYM
dymeclin
chr12_-_11214893 0.46 ENST00000533467.1
TAS2R46
taste receptor, type 2, member 46
chr6_-_27100529 0.46 ENST00000607124.1
ENST00000339812.2
ENST00000541790.1
HIST1H2BJ
histone cluster 1, H2bj
chr6_-_26235206 0.45 ENST00000244534.5
HIST1H1D
histone cluster 1, H1d
chr14_-_23446003 0.45 ENST00000553911.1
AJUBA
ajuba LIM protein
chr8_+_39972170 0.45 ENST00000521257.1
RP11-359E19.2
RP11-359E19.2
chr22_-_24096630 0.44 ENST00000248948.3
VPREB3
pre-B lymphocyte 3
chr2_+_10861775 0.43 ENST00000272238.4
ENST00000381661.3
ATP6V1C2
ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2
chr10_+_119184702 0.43 ENST00000549104.1
CTA-109P11.4
CTA-109P11.4
chr6_+_160693591 0.42 ENST00000419196.1
RP1-276N6.2
RP1-276N6.2
chr17_+_14204389 0.42 ENST00000360954.2
HS3ST3B1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chr6_+_76599809 0.42 ENST00000430435.1
MYO6
myosin VI
chr19_-_41903161 0.41 ENST00000602129.1
ENST00000593771.1
ENST00000596905.1
ENST00000221233.4
EXOSC5
exosome component 5
chr6_+_22221010 0.41 ENST00000567753.1
RP11-524C21.2
RP11-524C21.2
chr3_-_186262166 0.40 ENST00000307944.5
CRYGS
crystallin, gamma S
chr7_+_112120908 0.40 ENST00000439068.2
ENST00000312849.4
ENST00000429049.1
LSMEM1
leucine-rich single-pass membrane protein 1
chr10_+_6392278 0.39 ENST00000391437.1
DKFZP667F0711
DKFZP667F0711
chr19_+_17337027 0.38 ENST00000601529.1
ENST00000600232.1
OCEL1
occludin/ELL domain containing 1
chr7_+_135611542 0.38 ENST00000416501.1
AC015987.2
AC015987.2
chr2_-_158182105 0.37 ENST00000409925.1
ERMN
ermin, ERM-like protein
chr2_-_207082748 0.36 ENST00000407325.2
ENST00000411719.1
GPR1
G protein-coupled receptor 1
chr1_-_27709793 0.36 ENST00000374027.3
ENST00000374025.3
CD164L2
CD164 sialomucin-like 2
chr12_-_123201337 0.36 ENST00000528880.2
HCAR3
hydroxycarboxylic acid receptor 3
chr19_+_18726786 0.36 ENST00000594709.1
TMEM59L
transmembrane protein 59-like
chr12_-_102591604 0.36 ENST00000329406.4
PMCH
pro-melanin-concentrating hormone
chr17_+_42925270 0.36 ENST00000253410.2
ENST00000587021.1
HIGD1B
HIG1 hypoxia inducible domain family, member 1B
chr12_+_7053228 0.36 ENST00000540506.2
C12orf57
chromosome 12 open reading frame 57
chr16_+_56969284 0.36 ENST00000568358.1
HERPUD1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chrX_-_55208866 0.36 ENST00000545075.1
MTRNR2L10
MT-RNR2-like 10
chr6_+_27833034 0.35 ENST00000357320.2
HIST1H2AL
histone cluster 1, H2al
chr20_-_29896388 0.35 ENST00000400549.1
DEFB116
defensin, beta 116
chr9_+_125796806 0.35 ENST00000373642.1
GPR21
G protein-coupled receptor 21
chr12_+_78359999 0.35 ENST00000550503.1
NAV3
neuron navigator 3
chr19_+_21203481 0.34 ENST00000595401.1
ZNF430
zinc finger protein 430
chr1_+_59775752 0.34 ENST00000371212.1
FGGY
FGGY carbohydrate kinase domain containing
chr1_+_149822620 0.34 ENST00000369159.2
HIST2H2AA4
histone cluster 2, H2aa4
chr12_+_43086018 0.34 ENST00000550177.1
RP11-25I15.3
RP11-25I15.3
chr1_-_8000872 0.33 ENST00000377507.3
TNFRSF9
tumor necrosis factor receptor superfamily, member 9
chr2_+_74120094 0.33 ENST00000409731.3
ENST00000345517.3
ENST00000409918.1
ENST00000442912.1
ENST00000409624.1
ACTG2
actin, gamma 2, smooth muscle, enteric
chr19_-_23456996 0.33 ENST00000594653.1
RP11-15H20.7
RP11-15H20.7
chr19_+_41305330 0.32 ENST00000593972.1
EGLN2
egl-9 family hypoxia-inducible factor 2
chr7_+_140378955 0.32 ENST00000473512.1
ADCK2
aarF domain containing kinase 2
chr3_-_167191814 0.31 ENST00000466903.1
ENST00000264677.4
SERPINI2
serpin peptidase inhibitor, clade I (pancpin), member 2
chr1_-_149858227 0.31 ENST00000369155.2
HIST2H2BE
histone cluster 2, H2be
chr12_+_122064398 0.31 ENST00000330079.7
ORAI1
ORAI calcium release-activated calcium modulator 1
chr21_+_35107346 0.31 ENST00000456489.1
ITSN1
intersectin 1 (SH3 domain protein)
chr6_+_27100811 0.31 ENST00000359193.2
HIST1H2AG
histone cluster 1, H2ag
chr7_+_141463897 0.31 ENST00000247879.2
TAS2R3
taste receptor, type 2, member 3
chr9_-_35079911 0.31 ENST00000448890.1
FANCG
Fanconi anemia, complementation group G
chr19_+_39903185 0.30 ENST00000409794.3
PLEKHG2
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr12_+_113344811 0.30 ENST00000551241.1
ENST00000553185.1
ENST00000550689.1
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr4_-_38806404 0.30 ENST00000308979.2
ENST00000505940.1
ENST00000515861.1
TLR1
toll-like receptor 1
chr2_-_158182322 0.30 ENST00000420719.2
ENST00000409216.1
ERMN
ermin, ERM-like protein
chr4_+_2043689 0.29 ENST00000382878.3
ENST00000409248.4
C4orf48
chromosome 4 open reading frame 48
chr17_-_38256973 0.29 ENST00000246672.3
NR1D1
nuclear receptor subfamily 1, group D, member 1
chr12_+_7053172 0.29 ENST00000229281.5
C12orf57
chromosome 12 open reading frame 57
chr1_-_149814478 0.29 ENST00000369161.3
HIST2H2AA3
histone cluster 2, H2aa3
chr1_+_218683438 0.29 ENST00000443836.1
C1orf143
chromosome 1 open reading frame 143
chr4_+_2043777 0.29 ENST00000409860.1
C4orf48
chromosome 4 open reading frame 48
chr3_+_151591422 0.28 ENST00000362032.5
SUCNR1
succinate receptor 1
chr14_+_97925151 0.28 ENST00000554862.1
ENST00000554260.1
ENST00000499910.2
CTD-2506J14.1
CTD-2506J14.1
chr6_-_31651817 0.28 ENST00000375863.3
ENST00000375860.2
LY6G5C
lymphocyte antigen 6 complex, locus G5C
chr12_-_100656134 0.28 ENST00000548313.1
DEPDC4
DEP domain containing 4
chr20_+_361890 0.27 ENST00000449710.1
ENST00000422053.2
TRIB3
tribbles pseudokinase 3
chr1_-_211752073 0.27 ENST00000367001.4
SLC30A1
solute carrier family 30 (zinc transporter), member 1
chr1_-_6052463 0.27 ENST00000378156.4
NPHP4
nephronophthisis 4
chr14_-_23446021 0.27 ENST00000553592.1
AJUBA
ajuba LIM protein
chr17_+_73084038 0.27 ENST00000578376.1
ENST00000329783.4
SLC16A5
solute carrier family 16 (monocarboxylate transporter), member 5
chr14_+_53019993 0.27 ENST00000542169.2
ENST00000555622.1
GPR137C
G protein-coupled receptor 137C
chrX_-_30871004 0.27 ENST00000378928.1
TAB3
TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr11_-_73687997 0.26 ENST00000545212.1
UCP2
uncoupling protein 2 (mitochondrial, proton carrier)
chr19_+_17516531 0.26 ENST00000528911.1
ENST00000528604.1
ENST00000595892.1
ENST00000500836.2
ENST00000598546.1
ENST00000600369.1
ENST00000598356.1
ENST00000594426.1
MVB12A
CTD-2521M24.9
multivesicular body subunit 12A
CTD-2521M24.9
chr11_-_64085533 0.25 ENST00000544844.1
TRMT112
tRNA methyltransferase 11-2 homolog (S. cerevisiae)
chr6_+_27861190 0.25 ENST00000303806.4
HIST1H2BO
histone cluster 1, H2bo
chr1_+_32538520 0.25 ENST00000438825.1
ENST00000456834.2
ENST00000373634.4
ENST00000427288.1
TMEM39B
transmembrane protein 39B
chr11_-_64084959 0.25 ENST00000535750.1
ENST00000535126.1
ENST00000539854.1
ENST00000308774.2
TRMT112
tRNA methyltransferase 11-2 homolog (S. cerevisiae)
chr1_+_33722080 0.24 ENST00000483388.1
ENST00000539719.1
ZNF362
zinc finger protein 362
chr11_-_3663480 0.24 ENST00000397068.3
ART5
ADP-ribosyltransferase 5
chr1_+_207262881 0.24 ENST00000451804.2
C4BPB
complement component 4 binding protein, beta
chr7_+_27282319 0.24 ENST00000222761.3
EVX1
even-skipped homeobox 1
chr7_+_116660246 0.24 ENST00000434836.1
ENST00000393443.1
ENST00000465133.1
ENST00000477742.1
ENST00000393447.4
ENST00000393444.3
ST7
suppression of tumorigenicity 7
chr6_+_26199737 0.23 ENST00000359985.1
HIST1H2BF
histone cluster 1, H2bf
chr11_-_26743546 0.23 ENST00000280467.6
ENST00000396005.3
SLC5A12
solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12
chr2_-_190927447 0.23 ENST00000260950.4
MSTN
myostatin
chr1_+_201979743 0.23 ENST00000446188.1
ELF3
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr7_-_37024665 0.23 ENST00000396040.2
ELMO1
engulfment and cell motility 1
chr15_+_84115868 0.23 ENST00000427482.2
SH3GL3
SH3-domain GRB2-like 3
chr16_-_69418553 0.23 ENST00000569542.2
TERF2
telomeric repeat binding factor 2
chr19_+_45445491 0.23 ENST00000592954.1
ENST00000419266.2
ENST00000589057.1
APOC4
APOC4-APOC2
apolipoprotein C-IV
APOC4-APOC2 readthrough (NMD candidate)
chr12_+_120740119 0.23 ENST00000536460.1
ENST00000202967.4
SIRT4
sirtuin 4
chr1_-_23886285 0.23 ENST00000374561.5
ID3
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr2_+_196521458 0.23 ENST00000409086.3
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr10_+_71561630 0.23 ENST00000398974.3
ENST00000398971.3
ENST00000398968.3
ENST00000398966.3
ENST00000398964.3
ENST00000398969.3
ENST00000356340.3
ENST00000398972.3
ENST00000398973.3
COL13A1
collagen, type XIII, alpha 1
chr10_+_96698406 0.22 ENST00000260682.6
CYP2C9
cytochrome P450, family 2, subfamily C, polypeptide 9
chr4_-_99578789 0.22 ENST00000511651.1
ENST00000505184.1
TSPAN5
tetraspanin 5
chr1_+_32538492 0.22 ENST00000336294.5
TMEM39B
transmembrane protein 39B
chr19_-_12267524 0.22 ENST00000455799.1
ENST00000355738.1
ENST00000439556.2
ENST00000542938.1
ZNF625
zinc finger protein 625
chr12_+_132312931 0.22 ENST00000360564.1
ENST00000545671.1
ENST00000545790.1
MMP17
matrix metallopeptidase 17 (membrane-inserted)
chr6_+_155538093 0.22 ENST00000462408.2
TIAM2
T-cell lymphoma invasion and metastasis 2
chr12_+_79357815 0.22 ENST00000547046.1
SYT1
synaptotagmin I
chr6_-_138820624 0.22 ENST00000343505.5
NHSL1
NHS-like 1
chr2_+_145780739 0.22 ENST00000597173.1
ENST00000602108.1
ENST00000420472.1
TEX41
testis expressed 41 (non-protein coding)
chrX_-_48776292 0.22 ENST00000376509.4
PIM2
pim-2 oncogene
chr15_+_84116106 0.22 ENST00000535412.1
ENST00000324537.5
SH3GL3
SH3-domain GRB2-like 3
chr19_+_19144666 0.21 ENST00000535288.1
ENST00000538663.1
ARMC6
armadillo repeat containing 6
chr10_+_91061712 0.21 ENST00000371826.3
IFIT2
interferon-induced protein with tetratricopeptide repeats 2
chr12_-_74796291 0.21 ENST00000551726.1
RP11-81H3.2
RP11-81H3.2
chr7_+_22766766 0.21 ENST00000426291.1
ENST00000401651.1
ENST00000258743.5
ENST00000420258.2
ENST00000407492.1
ENST00000401630.3
ENST00000406575.1
IL6
interleukin 6 (interferon, beta 2)
chr6_+_151358048 0.20 ENST00000450635.1
MTHFD1L
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr19_+_17337406 0.20 ENST00000597836.1
OCEL1
occludin/ELL domain containing 1
chr17_+_46133307 0.20 ENST00000580037.1
NFE2L1
nuclear factor, erythroid 2-like 1
chr7_+_102553430 0.20 ENST00000339431.4
ENST00000249377.4
LRRC17
leucine rich repeat containing 17
chr9_-_140196703 0.20 ENST00000356628.2
NRARP
NOTCH-regulated ankyrin repeat protein
chr1_-_238108575 0.20 ENST00000604646.1
MTRNR2L11
MT-RNR2-like 11 (pseudogene)
chr1_+_192778161 0.20 ENST00000235382.5
RGS2
regulator of G-protein signaling 2, 24kDa
chr22_-_46450024 0.20 ENST00000396008.2
ENST00000333761.1
C22orf26
chromosome 22 open reading frame 26
chr10_-_91403625 0.20 ENST00000322191.6
ENST00000342512.3
ENST00000371774.2
PANK1
pantothenate kinase 1
chr2_+_176981307 0.20 ENST00000249501.4
HOXD10
homeobox D10
chr12_+_7052974 0.19 ENST00000544681.1
ENST00000537087.1
C12orf57
chromosome 12 open reading frame 57
chr3_-_58200398 0.19 ENST00000318316.3
ENST00000460422.1
ENST00000483681.1
DNASE1L3
deoxyribonuclease I-like 3
chr5_-_172198190 0.19 ENST00000239223.3
DUSP1
dual specificity phosphatase 1
chr6_-_29527702 0.19 ENST00000377050.4
UBD
ubiquitin D
chr9_+_35042205 0.19 ENST00000312292.5
ENST00000378745.3
C9orf131
chromosome 9 open reading frame 131
chrX_-_57164058 0.19 ENST00000374906.3
SPIN2A
spindlin family, member 2A
chr2_+_219264762 0.19 ENST00000452977.1
CTDSP1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr10_+_106113515 0.19 ENST00000369704.3
ENST00000312902.5
CCDC147
coiled-coil domain containing 147
chr17_-_57158523 0.19 ENST00000581468.1
TRIM37
tripartite motif containing 37
chr12_+_133707204 0.19 ENST00000426665.2
ZNF10
zinc finger protein 10
chr18_+_77905894 0.19 ENST00000589574.1
ENST00000588226.1
ENST00000585422.1
AC139100.2
Uncharacterized protein
chr20_-_61733657 0.19 ENST00000608031.1
ENST00000447910.2
HAR1B
highly accelerated region 1B (non-protein coding)
chr16_-_18911366 0.19 ENST00000565224.1
SMG1
SMG1 phosphatidylinositol 3-kinase-related kinase
chr15_-_76352069 0.19 ENST00000305435.10
ENST00000563910.1
NRG4
neuregulin 4
chr3_-_192445289 0.19 ENST00000430714.1
ENST00000418610.1
ENST00000448795.1
ENST00000445105.2
FGF12
fibroblast growth factor 12
chr18_-_56985873 0.19 ENST00000299721.3
CPLX4
complexin 4
chr19_-_50143452 0.19 ENST00000246792.3
RRAS
related RAS viral (r-ras) oncogene homolog
chr17_+_72426891 0.19 ENST00000392627.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr21_-_36260980 0.19 ENST00000344691.4
ENST00000358356.5
RUNX1
runt-related transcription factor 1
chr2_-_211036051 0.18 ENST00000418791.1
ENST00000452086.1
ENST00000281772.9
KANSL1L
KAT8 regulatory NSL complex subunit 1-like
chr2_+_173686303 0.18 ENST00000397087.3
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr11_+_94706804 0.18 ENST00000335080.5
KDM4D
lysine (K)-specific demethylase 4D
chr1_-_72748417 0.18 ENST00000357731.5
NEGR1
neuronal growth regulator 1
chr17_+_41052808 0.18 ENST00000592383.1
ENST00000253801.2
ENST00000585489.1
G6PC
glucose-6-phosphatase, catalytic subunit
chr8_+_66619277 0.18 ENST00000521247.2
ENST00000527155.1
MTFR1
mitochondrial fission regulator 1
chr22_+_32750872 0.18 ENST00000397468.1
RFPL3
ret finger protein-like 3
chr12_-_49333446 0.18 ENST00000537495.1
AC073610.5
Uncharacterized protein
chr15_-_80695917 0.18 ENST00000559008.1
RP11-210M15.2
Uncharacterized protein
chr19_+_14693888 0.18 ENST00000547437.1
ENST00000397439.2
ENST00000417570.1
CLEC17A
C-type lectin domain family 17, member A
chr8_-_33370607 0.18 ENST00000360742.5
ENST00000523305.1
TTI2
TELO2 interacting protein 2
chr19_+_17337473 0.18 ENST00000598068.1
OCEL1
occludin/ELL domain containing 1
chr6_-_13621126 0.18 ENST00000600057.1
AL441883.1
Uncharacterized protein
chr2_-_70529126 0.18 ENST00000438759.1
ENST00000430566.1
FAM136A
family with sequence similarity 136, member A
chr6_+_155470243 0.17 ENST00000456877.2
ENST00000528391.2
TIAM2
T-cell lymphoma invasion and metastasis 2
chr8_+_86121448 0.17 ENST00000520225.1
E2F5
E2F transcription factor 5, p130-binding
chr20_-_60982330 0.17 ENST00000279101.5
CABLES2
Cdk5 and Abl enzyme substrate 2
chr19_+_21541732 0.17 ENST00000311015.3
ZNF738
zinc finger protein 738
chr1_-_157789850 0.17 ENST00000491942.1
ENST00000358292.3
ENST00000368176.3
FCRL1
Fc receptor-like 1
chr17_+_9479944 0.17 ENST00000396219.3
ENST00000352665.5
WDR16
WD repeat domain 16
chrX_+_12993336 0.17 ENST00000380635.1
TMSB4X
thymosin beta 4, X-linked
chr1_+_116519223 0.17 ENST00000369502.1
SLC22A15
solute carrier family 22, member 15
chr18_-_53255766 0.17 ENST00000566286.1
ENST00000564999.1
ENST00000566279.1
ENST00000354452.3
ENST00000356073.4
TCF4
transcription factor 4
chr12_+_122064673 0.17 ENST00000537188.1
ORAI1
ORAI calcium release-activated calcium modulator 1
chr17_+_27369918 0.17 ENST00000323372.4
PIPOX
pipecolic acid oxidase
chr18_-_52989525 0.17 ENST00000457482.3
TCF4
transcription factor 4
chr12_+_54384370 0.17 ENST00000504315.1
HOXC6
homeobox C6
chr10_-_37891859 0.17 ENST00000544824.1
MTRNR2L7
MT-RNR2-like 7
chr18_-_47017956 0.17 ENST00000584895.1
ENST00000332968.6
ENST00000580210.1
ENST00000579408.1
RPL17-C18orf32
RPL17
RPL17-C18orf32 readthrough
ribosomal protein L17
chr11_-_57417405 0.17 ENST00000524669.1
ENST00000300022.3
YPEL4
yippee-like 4 (Drosophila)

Network of associatons between targets according to the STRING database.

First level regulatory network of POU5F1_POU2F3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.6 GO:0002227 innate immune response in mucosa(GO:0002227)
0.1 0.7 GO:0036343 psychomotor behavior(GO:0036343)
0.1 0.5 GO:0002678 positive regulation of chronic inflammatory response(GO:0002678)
0.1 0.5 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
0.1 0.3 GO:0060086 circadian temperature homeostasis(GO:0060086)
0.1 0.4 GO:1903824 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208) negative regulation of single strand break repair(GO:1903517) negative regulation of beta-galactosidase activity(GO:1903770) telomere single strand break repair(GO:1903823) negative regulation of telomere single strand break repair(GO:1903824)
0.1 0.3 GO:0070340 detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.1 0.3 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.1 0.6 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.1 0.4 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 0.3 GO:2001183 negative regulation of interleukin-12 secretion(GO:2001183)
0.1 0.4 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.1 0.2 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.1 0.2 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.1 0.2 GO:1903216 regulation of protein processing involved in protein targeting to mitochondrion(GO:1903216) negative regulation of protein processing involved in protein targeting to mitochondrion(GO:1903217)
0.1 0.2 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.1 0.2 GO:0045720 negative regulation of integrin biosynthetic process(GO:0045720)
0.1 0.3 GO:0090131 mesenchyme migration(GO:0090131)
0.1 0.1 GO:0035494 SNARE complex disassembly(GO:0035494)
0.1 0.2 GO:0002740 negative regulation of cytokine secretion involved in immune response(GO:0002740)
0.1 0.4 GO:0097501 detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.1 0.2 GO:0002384 hepatic immune response(GO:0002384) response to prolactin(GO:1990637)
0.1 0.2 GO:0031296 B cell costimulation(GO:0031296)
0.1 0.5 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.1 GO:0002121 inter-male aggressive behavior(GO:0002121)
0.0 0.1 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.0 0.2 GO:1903613 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.0 5.1 GO:0006342 chromatin silencing(GO:0006342)
0.0 0.1 GO:0021569 rhombomere 3 development(GO:0021569) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 6.6 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.1 GO:1902568 regulation of eosinophil degranulation(GO:0043309) positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.0 0.3 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.0 0.2 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.0 0.1 GO:0061386 closure of optic fissure(GO:0061386)
0.0 0.2 GO:0034343 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.0 0.2 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.0 0.3 GO:0019075 virus maturation(GO:0019075)
0.0 0.1 GO:1904995 negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995)
0.0 0.4 GO:0070842 aggresome assembly(GO:0070842)
0.0 0.1 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.1 GO:0035281 pre-miRNA export from nucleus(GO:0035281)
0.0 0.2 GO:0042078 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0 0.1 GO:0072684 mitochondrial tRNA 3'-trailer cleavage, endonucleolytic(GO:0072684)
0.0 0.2 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.0 0.2 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.0 0.1 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.0 0.4 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.1 GO:2000744 anterior head development(GO:0097065) spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.0 0.1 GO:1990051 activation of protein kinase C activity(GO:1990051)
0.0 0.2 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.2 GO:0048539 bone marrow development(GO:0048539)
0.0 0.3 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.1 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.0 0.1 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.0 0.5 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.1 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.0 0.2 GO:0010519 negative regulation of phospholipase activity(GO:0010519)
0.0 0.2 GO:0019474 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.0 0.3 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.2 GO:0030450 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.0 0.1 GO:0097535 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.0 0.2 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.1 GO:0038163 endomitotic cell cycle(GO:0007113) thrombopoietin-mediated signaling pathway(GO:0038163)
0.0 0.1 GO:0044111 development involved in symbiotic interaction(GO:0044111)
0.0 0.1 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.0 0.2 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.1 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0 0.1 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.1 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.1 GO:0019242 methylglyoxal biosynthetic process(GO:0019242)
0.0 0.1 GO:2000111 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185) positive regulation of macrophage apoptotic process(GO:2000111)
0.0 0.2 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.1 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 0.1 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
0.0 0.4 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0 0.1 GO:0001172 transcription, RNA-templated(GO:0001172)
0.0 0.2 GO:0015727 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.0 0.2 GO:0098908 regulation of neuronal action potential(GO:0098908)
0.0 0.3 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.2 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.1 GO:0061198 glial cell fate determination(GO:0007403) fungiform papilla formation(GO:0061198) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793)
0.0 0.2 GO:0034447 very-low-density lipoprotein particle clearance(GO:0034447)
0.0 0.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.1 GO:1901073 N-acetylglucosamine biosynthetic process(GO:0006045) glucosamine-containing compound biosynthetic process(GO:1901073)
0.0 0.1 GO:0009956 radial pattern formation(GO:0009956)
0.0 0.1 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.0 0.1 GO:0019566 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.0 0.4 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.0 GO:0001711 endodermal cell fate commitment(GO:0001711) endodermal cell fate specification(GO:0001714)
0.0 0.1 GO:0030047 actin modification(GO:0030047)
0.0 0.1 GO:0045348 positive regulation of MHC class II biosynthetic process(GO:0045348)
0.0 0.1 GO:0009149 pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213)
0.0 0.1 GO:1903169 regulation of calcium ion transmembrane transport(GO:1903169)
0.0 0.2 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.7 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.1 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.0 0.1 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.0 0.3 GO:0002576 platelet degranulation(GO:0002576)
0.0 0.1 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.0 0.1 GO:0019303 D-ribose catabolic process(GO:0019303)
0.0 0.1 GO:0031125 rRNA 3'-end processing(GO:0031125)
0.0 0.2 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 0.1 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.1 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.0 0.1 GO:2000811 negative regulation of anoikis(GO:2000811)
0.0 0.1 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.0 0.1 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.1 GO:0014738 regulation of muscle hyperplasia(GO:0014738) negative regulation of muscle hyperplasia(GO:0014740)
0.0 0.1 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.2 GO:0070970 interleukin-2 secretion(GO:0070970)
0.0 0.1 GO:0097473 cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.0 0.1 GO:1904209 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.0 0.1 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 0.1 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.0 0.1 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.0 0.0 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.0 0.1 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.0 0.2 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.5 GO:0090383 phagosome acidification(GO:0090383)
0.0 0.0 GO:0016321 female meiosis chromosome segregation(GO:0016321)
0.0 0.1 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.0 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0 0.2 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.1 GO:0033004 negative regulation of mast cell activation(GO:0033004)
0.0 0.0 GO:0033484 nitric oxide homeostasis(GO:0033484)
0.0 0.0 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.0 0.1 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.1 GO:0060056 mammary gland involution(GO:0060056)
0.0 0.0 GO:0060694 regulation of cholesterol transporter activity(GO:0060694) negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.0 0.1 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 0.1 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.1 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.0 0.1 GO:0010989 negative regulation of lipoprotein particle clearance(GO:0010985) negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0 0.0 GO:0051097 negative regulation of helicase activity(GO:0051097) oligodendrocyte apoptotic process(GO:0097252)
0.0 0.0 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.0 0.1 GO:0031179 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
0.0 0.7 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.0 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 0.1 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.0 GO:0046041 ITP metabolic process(GO:0046041)
0.0 0.1 GO:0042756 drinking behavior(GO:0042756)
0.0 0.0 GO:0006597 spermine biosynthetic process(GO:0006597)
0.0 0.1 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 13.7 GO:0000786 nucleosome(GO:0000786)
0.1 0.4 GO:0030936 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.1 0.3 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.1 0.5 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 0.4 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.1 0.4 GO:1990037 Lewy body core(GO:1990037)
0.1 0.8 GO:0033269 internode region of axon(GO:0033269)
0.0 0.2 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.1 GO:0042565 RNA nuclear export complex(GO:0042565)
0.0 0.4 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.4 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.4 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.1 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.0 0.1 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 0.0 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.0 0.1 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.0 0.4 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.3 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.3 GO:0032982 myosin filament(GO:0032982)
0.0 0.1 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.0 0.1 GO:0060187 cell pole(GO:0060187)
0.0 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.1 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 0.1 GO:0089701 U2AF(GO:0089701)
0.0 0.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.2 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.0 GO:0035838 growing cell tip(GO:0035838)
0.0 0.4 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.0 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.1 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.2 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.0 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0060001 minus-end directed microfilament motor activity(GO:0060001)
0.1 0.5 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.1 0.6 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.1 0.5 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.1 0.3 GO:0019150 D-ribulokinase activity(GO:0019150)
0.1 0.3 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.1 0.2 GO:0004756 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.1 0.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.2 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1 0.2 GO:0047708 biotinidase activity(GO:0047708)
0.1 0.1 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 0.2 GO:0015235 cobalamin transporter activity(GO:0015235)
0.0 0.1 GO:0019862 IgA binding(GO:0019862)
0.0 0.1 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.2 GO:0033695 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 0.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.2 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.0 0.5 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.2 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.0 0.2 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.3 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.2 GO:0042806 fucose binding(GO:0042806)
0.0 0.1 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.0 0.1 GO:0004513 neolactotetraosylceramide alpha-2,3-sialyltransferase activity(GO:0004513) lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
0.0 0.1 GO:0090631 pre-miRNA transporter activity(GO:0090631)
0.0 0.8 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.3 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.1 GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113)
0.0 0.1 GO:0003968 RNA-directed RNA polymerase activity(GO:0003968)
0.0 0.2 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.4 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.1 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.0 0.2 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.4 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.6 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.5 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.2 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.2 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.1 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.0 0.1 GO:0042781 3'-tRNA processing endoribonuclease activity(GO:0042781)
0.0 0.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.1 GO:0004556 alpha-amylase activity(GO:0004556)
0.0 0.1 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.1 GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761) N-acylmannosamine kinase activity(GO:0009384)
0.0 0.1 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.0 1.5 GO:0030552 cAMP binding(GO:0030552)
0.0 0.1 GO:0004347 glucose-6-phosphate isomerase activity(GO:0004347)
0.0 0.1 GO:0046969 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.0 0.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.2 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.1 GO:0042019 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.4 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.1 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.1 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.0 0.1 GO:0015119 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.1 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.2 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.2 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.1 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.0 0.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.0 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.2 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.1 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 11.1 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.0 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.0 0.1 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.0 0.1 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 0.0 GO:0033677 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) DNA/RNA helicase activity(GO:0033677)
0.0 0.1 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.0 GO:0016768 spermine synthase activity(GO:0016768)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.1 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.2 GO:0046870 cadmium ion binding(GO:0046870)
0.0 0.1 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.1 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0 0.1 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.6 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.0 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.0 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.1 GO:0042835 BRE binding(GO:0042835)
0.0 0.1 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.2 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.2 ST STAT3 PATHWAY STAT3 Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 15.4 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.1 0.8 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.5 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.1 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.4 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.5 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.6 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.4 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.5 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.5 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.5 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.2 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.5 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.9 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.1 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.4 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.2 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling