Project

A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

Navigation
Downloads

Results for PRDM4

Z-value: 0.73

Motif logo

logo of

Transcription factors associated with PRDM4

Gene Symbol Gene ID Gene Info
PRDM4
ENSG00000110851.7 PR/SET domain 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PRDM4hg19_v2_chr12_-_108154705_1081547760.881.2e-01Click!

Activity profile of PRDM4 motif

Sorted Z-values of PRDM4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_233734994 0.81 ENST00000331342.2
C2orf82
chromosome 2 open reading frame 82
chr6_+_26045603 0.75 ENST00000540144.1
HIST1H3C
histone cluster 1, H3c
chr17_+_42634844 0.59 ENST00000315323.3
FZD2
frizzled family receptor 2
chr10_+_88728189 0.53 ENST00000416348.1
ADIRF
adipogenesis regulatory factor
chr2_+_219264466 0.51 ENST00000273062.2
CTDSP1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr20_-_49639631 0.49 ENST00000424171.1
ENST00000439216.1
ENST00000371571.4
KCNG1
potassium voltage-gated channel, subfamily G, member 1
chr1_+_27113963 0.49 ENST00000430292.1
PIGV
phosphatidylinositol glycan anchor biosynthesis, class V
chr5_-_78281623 0.37 ENST00000521117.1
ARSB
arylsulfatase B
chr1_+_43232913 0.35 ENST00000372525.5
ENST00000536543.1
C1orf50
chromosome 1 open reading frame 50
chr6_-_32160622 0.31 ENST00000487761.1
ENST00000375040.3
GPSM3
G-protein signaling modulator 3
chr6_-_24721054 0.28 ENST00000378119.4
C6orf62
chromosome 6 open reading frame 62
chr9_+_139560197 0.27 ENST00000371698.3
EGFL7
EGF-like-domain, multiple 7
chr11_-_67188642 0.27 ENST00000546202.1
ENST00000542876.1
PPP1CA
protein phosphatase 1, catalytic subunit, alpha isozyme
chr20_-_49639612 0.25 ENST00000396017.3
ENST00000433903.1
KCNG1
potassium voltage-gated channel, subfamily G, member 1
chr4_+_667307 0.24 ENST00000506838.1
MYL5
myosin, light chain 5, regulatory
chr16_+_29823427 0.24 ENST00000358758.7
ENST00000567659.1
ENST00000572820.1
PRRT2
proline-rich transmembrane protein 2
chr7_+_90893783 0.23 ENST00000287934.2
FZD1
frizzled family receptor 1
chr19_+_42724423 0.22 ENST00000301215.3
ENST00000597945.1
ZNF526
zinc finger protein 526
chr14_-_24732738 0.22 ENST00000558074.1
ENST00000560226.1
TGM1
transglutaminase 1
chr19_-_11639910 0.22 ENST00000588998.1
ENST00000586149.1
ECSIT
ECSIT signalling integrator
chr14_+_32030582 0.21 ENST00000550649.1
ENST00000281081.7
NUBPL
nucleotide binding protein-like
chr2_+_219264762 0.20 ENST00000452977.1
CTDSP1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr12_+_104682667 0.18 ENST00000527335.1
TXNRD1
thioredoxin reductase 1
chr1_+_171750776 0.18 ENST00000458517.1
ENST00000362019.3
ENST00000367737.5
ENST00000361735.3
METTL13
methyltransferase like 13
chr5_+_159343688 0.17 ENST00000306675.3
ADRA1B
adrenoceptor alpha 1B
chr2_+_234296792 0.17 ENST00000409813.3
DGKD
diacylglycerol kinase, delta 130kDa
chr19_+_41117770 0.15 ENST00000601032.1
LTBP4
latent transforming growth factor beta binding protein 4
chr15_+_74287035 0.14 ENST00000395132.2
ENST00000268059.6
ENST00000354026.6
ENST00000268058.3
ENST00000565898.1
ENST00000569477.1
ENST00000569965.1
ENST00000567543.1
ENST00000436891.3
ENST00000435786.2
ENST00000564428.1
ENST00000359928.4
PML
promyelocytic leukemia
chr16_+_29823552 0.14 ENST00000300797.6
PRRT2
proline-rich transmembrane protein 2
chr14_+_24025194 0.13 ENST00000404535.3
ENST00000288014.6
THTPA
thiamine triphosphatase
chr12_+_104682496 0.12 ENST00000378070.4
TXNRD1
thioredoxin reductase 1
chr4_-_83295296 0.12 ENST00000507010.1
ENST00000503822.1
HNRNPD
heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
chr1_+_27114589 0.12 ENST00000431541.1
ENST00000449950.2
ENST00000374145.1
PIGV
phosphatidylinositol glycan anchor biosynthesis, class V
chr1_+_27114418 0.11 ENST00000078527.4
PIGV
phosphatidylinositol glycan anchor biosynthesis, class V
chr10_-_105212141 0.09 ENST00000369788.3
CALHM2
calcium homeostasis modulator 2
chr5_-_78281603 0.09 ENST00000264914.4
ARSB
arylsulfatase B
chr7_+_143078652 0.08 ENST00000354434.4
ENST00000449423.2
ZYX
zyxin
chr14_-_74462922 0.08 ENST00000553284.1
ENTPD5
ectonucleoside triphosphate diphosphohydrolase 5
chr14_+_24025345 0.08 ENST00000557630.1
THTPA
thiamine triphosphatase
chr5_-_78281775 0.08 ENST00000396151.3
ENST00000565165.1
ARSB
arylsulfatase B
chr12_+_50794947 0.07 ENST00000552445.1
LARP4
La ribonucleoprotein domain family, member 4
chr16_+_15068916 0.05 ENST00000455313.2
PDXDC1
pyridoxal-dependent decarboxylase domain containing 1
chr4_-_83295103 0.05 ENST00000313899.7
ENST00000352301.4
ENST00000509107.1
ENST00000353341.4
ENST00000541060.1
HNRNPD
heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
chr17_+_7788104 0.04 ENST00000380358.4
CHD3
chromodomain helicase DNA binding protein 3
chr16_+_15068831 0.04 ENST00000535621.2
ENST00000566426.1
PDXDC1
pyridoxal-dependent decarboxylase domain containing 1
chr15_+_66797627 0.04 ENST00000565627.1
ENST00000564179.1
ZWILCH
zwilch kinetochore protein
chr15_-_66797172 0.03 ENST00000569438.1
ENST00000569696.1
ENST00000307961.6
RPL4
ribosomal protein L4
chr1_+_151043070 0.03 ENST00000368918.3
ENST00000368917.1
GABPB2
GA binding protein transcription factor, beta subunit 2
chr20_+_62697564 0.03 ENST00000458442.1
TCEA2
transcription elongation factor A (SII), 2
chr19_-_11639931 0.03 ENST00000592312.1
ENST00000590480.1
ENST00000585318.1
ENST00000252440.7
ENST00000417981.2
ENST00000270517.7
ECSIT
ECSIT signalling integrator
chr20_+_30555805 0.03 ENST00000562532.2
XKR7
XK, Kell blood group complex subunit-related family, member 7
chr5_+_140261703 0.02 ENST00000409494.1
ENST00000289272.2
PCDHA13
protocadherin alpha 13
chr3_+_148709128 0.02 ENST00000345003.4
ENST00000296048.6
ENST00000483267.1
GYG1
glycogenin 1
chr1_-_161168834 0.02 ENST00000367995.3
ENST00000367996.5
ADAMTS4
ADAM metallopeptidase with thrombospondin type 1 motif, 4
chr16_+_88636875 0.02 ENST00000569435.1
ZC3H18
zinc finger CCCH-type containing 18
chr17_-_9929581 0.01 ENST00000437099.2
ENST00000396115.2
GAS7
growth arrest-specific 7
chr3_+_148709310 0.00 ENST00000484197.1
ENST00000492285.2
ENST00000461191.1
GYG1
glycogenin 1
chr8_+_91952750 0.00 ENST00000521366.1
NECAB1
N-terminal EF-hand calcium binding protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of PRDM4

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0061580 colon epithelial cell migration(GO:0061580)
0.1 0.2 GO:0035425 autocrine signaling(GO:0035425)
0.1 0.5 GO:2001023 cellular response to cisplatin(GO:0072719) regulation of response to drug(GO:2001023)
0.1 0.2 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.1 0.2 GO:1990828 response to putrescine(GO:1904585) cellular response to putrescine(GO:1904586) hepatocyte dedifferentiation(GO:1990828)
0.1 0.3 GO:0036496 regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496)
0.1 0.6 GO:0003150 muscular septum morphogenesis(GO:0003150)
0.0 0.2 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.0 0.2 GO:0043163 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.0 0.7 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.7 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.0 0.1 GO:0030578 PML body organization(GO:0030578)
0.0 0.3 GO:0001887 selenium compound metabolic process(GO:0001887)
0.0 0.4 GO:0050884 neuromuscular process controlling posture(GO:0050884)
0.0 0.3 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0031501 mannosyltransferase complex(GO:0031501)
0.0 0.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.3 GO:0042587 glycogen granule(GO:0042587)
0.0 0.2 GO:1990909 Wnt signalosome(GO:1990909)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0004584 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity(GO:0004584)
0.1 0.5 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.1 0.2 GO:0050333 thiamin-triphosphatase activity(GO:0050333)
0.1 0.3 GO:0098626 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
0.1 0.7 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.7 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.2 GO:0004936 alpha-adrenergic receptor activity(GO:0004936)
0.0 0.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.1 GO:0004382 guanosine-diphosphatase activity(GO:0004382)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.7 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.7 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.7 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.7 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening