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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for RELA

Z-value: 0.58

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Transcription factors associated with RELA

Gene Symbol Gene ID Gene Info
RELA
ENSG00000173039.14 RELA proto-oncogene, NF-kB subunit

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RELAhg19_v2_chr11_-_65430251_65430399-0.991.0e-02Click!

Activity profile of RELA motif

Sorted Z-values of RELA motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_6845578 0.52 ENST00000467404.2
ENST00000439411.2
CAMTA1
calmodulin binding transcription activator 1
chr6_+_138188378 0.52 ENST00000420009.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr19_-_39735646 0.39 ENST00000413851.2
IFNL3
interferon, lambda 3
chr1_+_6845497 0.38 ENST00000473578.1
ENST00000557126.1
CAMTA1
calmodulin binding transcription activator 1
chr19_+_39759154 0.37 ENST00000331982.5
IFNL2
interferon, lambda 2
chr17_-_34207295 0.35 ENST00000463941.1
ENST00000293272.3
CCL5
chemokine (C-C motif) ligand 5
chr6_+_138188551 0.33 ENST00000237289.4
ENST00000433680.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr4_-_76944621 0.32 ENST00000306602.1
CXCL10
chemokine (C-X-C motif) ligand 10
chr6_+_138188351 0.31 ENST00000421450.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr4_+_74735102 0.29 ENST00000395761.3
CXCL1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr11_+_102188224 0.27 ENST00000263464.3
BIRC3
baculoviral IAP repeat containing 3
chr15_+_33010175 0.26 ENST00000300177.4
ENST00000560677.1
ENST00000560830.1
GREM1
gremlin 1, DAN family BMP antagonist
chr9_-_21077939 0.25 ENST00000380232.2
IFNB1
interferon, beta 1, fibroblast
chr4_-_74864386 0.25 ENST00000296027.4
CXCL5
chemokine (C-X-C motif) ligand 5
chr14_-_35873856 0.24 ENST00000553342.1
ENST00000216797.5
ENST00000557140.1
NFKBIA
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
chr11_+_102188272 0.24 ENST00000532808.1
BIRC3
baculoviral IAP repeat containing 3
chr1_+_100818156 0.20 ENST00000336454.3
CDC14A
cell division cycle 14A
chr5_-_150460914 0.19 ENST00000389378.2
TNIP1
TNFAIP3 interacting protein 1
chr12_+_110718428 0.18 ENST00000552636.1
ATP2A2
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
chr2_+_29001711 0.18 ENST00000418910.1
PPP1CB
protein phosphatase 1, catalytic subunit, beta isozyme
chr20_-_44937124 0.18 ENST00000537909.1
CDH22
cadherin 22, type 2
chr10_+_18948311 0.18 ENST00000377275.3
ARL5B
ADP-ribosylation factor-like 5B
chr2_+_112895939 0.17 ENST00000331203.2
ENST00000409903.1
ENST00000409667.3
ENST00000409450.3
FBLN7
fibulin 7
chr20_+_1115821 0.17 ENST00000435720.1
PSMF1
proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
chr10_+_124739964 0.17 ENST00000406217.2
PSTK
phosphoseryl-tRNA kinase
chr13_-_52026730 0.17 ENST00000420668.2
INTS6
integrator complex subunit 6
chr5_-_150467221 0.17 ENST00000522226.1
TNIP1
TNFAIP3 interacting protein 1
chrX_-_131352152 0.17 ENST00000342983.2
RAP2C
RAP2C, member of RAS oncogene family
chr1_+_235490659 0.17 ENST00000488594.1
GGPS1
geranylgeranyl diphosphate synthase 1
chr5_-_55290773 0.17 ENST00000502326.3
ENST00000381298.2
IL6ST
interleukin 6 signal transducer (gp130, oncostatin M receptor)
chr2_+_61108650 0.16 ENST00000295025.8
REL
v-rel avian reticuloendotheliosis viral oncogene homolog
chr10_+_86088381 0.16 ENST00000224756.8
ENST00000372088.2
CCSER2
coiled-coil serine-rich protein 2
chr9_-_125667494 0.16 ENST00000335387.5
ENST00000357244.2
ENST00000373665.2
RC3H2
ring finger and CCCH-type domains 2
chr4_-_74904398 0.16 ENST00000296026.4
CXCL3
chemokine (C-X-C motif) ligand 3
chr13_-_52027134 0.15 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
INTS6
integrator complex subunit 6
chr9_-_125667618 0.15 ENST00000423239.2
RC3H2
ring finger and CCCH-type domains 2
chr12_-_49259643 0.15 ENST00000309739.5
RND1
Rho family GTPase 1
chr7_+_143013198 0.15 ENST00000343257.2
CLCN1
chloride channel, voltage-sensitive 1
chr16_-_28222797 0.14 ENST00000569951.1
ENST00000565698.1
XPO6
exportin 6
chr6_+_144471643 0.14 ENST00000367568.4
STX11
syntaxin 11
chr14_-_30396948 0.14 ENST00000331968.5
PRKD1
protein kinase D1
chr3_+_159706537 0.14 ENST00000305579.2
ENST00000480787.1
ENST00000466512.1
IL12A
interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
chr19_+_2476116 0.14 ENST00000215631.4
ENST00000587345.1
GADD45B
growth arrest and DNA-damage-inducible, beta
chr10_+_13141585 0.14 ENST00000378764.2
OPTN
optineurin
chr9_+_127054254 0.14 ENST00000422297.1
NEK6
NIMA-related kinase 6
chr2_+_61108771 0.14 ENST00000394479.3
REL
v-rel avian reticuloendotheliosis viral oncogene homolog
chr8_-_103668114 0.14 ENST00000285407.6
KLF10
Kruppel-like factor 10
chr10_+_13142225 0.14 ENST00000378747.3
OPTN
optineurin
chr10_+_12391685 0.14 ENST00000378845.1
CAMK1D
calcium/calmodulin-dependent protein kinase ID
chr6_-_150039249 0.14 ENST00000543571.1
LATS1
large tumor suppressor kinase 1
chr10_+_89124746 0.13 ENST00000465545.1
NUTM2D
NUT family member 2D
chr3_-_158390282 0.13 ENST00000264265.3
LXN
latexin
chr13_+_37581115 0.13 ENST00000481013.1
EXOSC8
exosome component 8
chr12_+_7053228 0.13 ENST00000540506.2
C12orf57
chromosome 12 open reading frame 57
chr11_-_46141338 0.13 ENST00000529782.1
ENST00000532010.1
ENST00000525438.1
ENST00000533757.1
ENST00000527782.1
PHF21A
PHD finger protein 21A
chrX_+_117861535 0.13 ENST00000371666.3
ENST00000371642.1
IL13RA1
interleukin 13 receptor, alpha 1
chr14_-_53417732 0.12 ENST00000399304.3
ENST00000395631.2
ENST00000341590.3
ENST00000343279.4
FERMT2
fermitin family member 2
chr4_+_103422471 0.12 ENST00000226574.4
ENST00000394820.4
NFKB1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr2_+_208394455 0.12 ENST00000430624.1
CREB1
cAMP responsive element binding protein 1
chr14_+_53196872 0.12 ENST00000442123.2
ENST00000354586.4
STYX
serine/threonine/tyrosine interacting protein
chr14_+_103243813 0.12 ENST00000560371.1
ENST00000347662.4
ENST00000392745.2
ENST00000539721.1
ENST00000560463.1
TRAF3
TNF receptor-associated factor 3
chr11_-_113644491 0.11 ENST00000200135.3
ZW10
zw10 kinetochore protein
chr22_-_28315115 0.11 ENST00000455418.3
ENST00000436663.1
ENST00000320996.10
ENST00000335272.5
PITPNB
phosphatidylinositol transfer protein, beta
chr19_-_14217672 0.11 ENST00000587372.1
PRKACA
protein kinase, cAMP-dependent, catalytic, alpha
chr17_-_58469329 0.11 ENST00000393003.3
USP32
ubiquitin specific peptidase 32
chr15_-_66084621 0.11 ENST00000564674.1
DENND4A
DENN/MADD domain containing 4A
chr2_+_64681641 0.11 ENST00000409537.2
LGALSL
lectin, galactoside-binding-like
chr19_-_50143452 0.11 ENST00000246792.3
RRAS
related RAS viral (r-ras) oncogene homolog
chr1_+_159796534 0.11 ENST00000289707.5
SLAMF8
SLAM family member 8
chr18_+_3252265 0.11 ENST00000580887.1
ENST00000536605.1
MYL12A
myosin, light chain 12A, regulatory, non-sarcomeric
chr1_+_100818009 0.11 ENST00000370125.2
ENST00000361544.6
ENST00000370124.3
CDC14A
cell division cycle 14A
chr5_+_159895275 0.10 ENST00000517927.1
MIR146A
microRNA 146a
chr15_+_52311398 0.10 ENST00000261845.5
MAPK6
mitogen-activated protein kinase 6
chr2_+_228678550 0.10 ENST00000409189.3
ENST00000358813.4
CCL20
chemokine (C-C motif) ligand 20
chr6_+_88299833 0.10 ENST00000392844.3
ENST00000257789.4
ENST00000546266.1
ENST00000417380.2
ORC3
origin recognition complex, subunit 3
chr1_-_65432171 0.10 ENST00000342505.4
JAK1
Janus kinase 1
chr20_+_18488528 0.10 ENST00000377465.1
SEC23B
Sec23 homolog B (S. cerevisiae)
chr6_-_31550192 0.10 ENST00000429299.2
ENST00000446745.2
LTB
lymphotoxin beta (TNF superfamily, member 3)
chr1_-_32403903 0.10 ENST00000344035.6
ENST00000356536.3
PTP4A2
protein tyrosine phosphatase type IVA, member 2
chr1_-_236030216 0.10 ENST00000389794.3
ENST00000389793.2
LYST
lysosomal trafficking regulator
chr4_-_74964904 0.10 ENST00000508487.2
CXCL2
chemokine (C-X-C motif) ligand 2
chr11_+_34642656 0.10 ENST00000257831.3
ENST00000450654.2
EHF
ets homologous factor
chr5_-_150460539 0.10 ENST00000520931.1
ENST00000520695.1
ENST00000521591.1
ENST00000518977.1
TNIP1
TNFAIP3 interacting protein 1
chr2_-_211036051 0.10 ENST00000418791.1
ENST00000452086.1
ENST00000281772.9
KANSL1L
KAT8 regulatory NSL complex subunit 1-like
chr21_+_34775772 0.10 ENST00000405436.1
IFNGR2
interferon gamma receptor 2 (interferon gamma transducer 1)
chr12_-_9913489 0.10 ENST00000228434.3
ENST00000536709.1
CD69
CD69 molecule
chr9_+_82188077 0.10 ENST00000425506.1
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr6_-_88299678 0.10 ENST00000369536.5
RARS2
arginyl-tRNA synthetase 2, mitochondrial
chr16_+_50775971 0.10 ENST00000311559.9
ENST00000564326.1
ENST00000566206.1
CYLD
cylindromatosis (turban tumor syndrome)
chr6_-_150039170 0.09 ENST00000458696.2
ENST00000392273.3
LATS1
large tumor suppressor kinase 1
chr16_-_28223166 0.09 ENST00000304658.5
XPO6
exportin 6
chr6_-_29527702 0.09 ENST00000377050.4
UBD
ubiquitin D
chr15_+_44719970 0.09 ENST00000558966.1
CTDSPL2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr5_+_133984462 0.09 ENST00000398844.2
ENST00000322887.4
SEC24A
SEC24 family member A
chr2_+_176957619 0.09 ENST00000392539.3
HOXD13
homeobox D13
chr15_-_71055878 0.09 ENST00000322954.6
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr12_-_117537240 0.09 ENST00000392545.4
ENST00000541210.1
ENST00000335209.7
TESC
tescalcin
chr3_+_197518100 0.09 ENST00000438796.2
ENST00000414675.2
ENST00000441090.2
ENST00000334859.4
ENST00000425562.2
LRCH3
leucine-rich repeats and calponin homology (CH) domain containing 3
chr1_+_169077133 0.09 ENST00000494797.1
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr11_-_72852958 0.09 ENST00000458644.2
FCHSD2
FCH and double SH3 domains 2
chr15_-_71055769 0.09 ENST00000539319.1
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr22_-_19512893 0.09 ENST00000403084.1
ENST00000413119.2
CLDN5
claudin 5
chr5_-_43313269 0.09 ENST00000511774.1
HMGCS1
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr12_-_48499591 0.09 ENST00000551330.1
ENST00000004980.5
ENST00000339976.6
ENST00000448372.1
SENP1
SUMO1/sentrin specific peptidase 1
chr16_+_50776021 0.09 ENST00000566679.2
ENST00000564634.1
ENST00000398568.2
CYLD
cylindromatosis (turban tumor syndrome)
chr6_-_17706618 0.09 ENST00000262077.2
ENST00000537253.1
NUP153
nucleoporin 153kDa
chr2_-_163175133 0.09 ENST00000421365.2
ENST00000263642.2
IFIH1
interferon induced with helicase C domain 1
chr1_+_26872324 0.08 ENST00000531382.1
RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr6_-_30080863 0.08 ENST00000540829.1
TRIM31
tripartite motif containing 31
chr20_+_44746885 0.08 ENST00000372285.3
CD40
CD40 molecule, TNF receptor superfamily member 5
chr16_-_53737722 0.08 ENST00000569716.1
ENST00000562588.1
ENST00000562230.1
ENST00000379925.3
ENST00000563746.1
ENST00000568653.3
RPGRIP1L
RPGRIP1-like
chr10_+_30723045 0.08 ENST00000542547.1
ENST00000415139.1
MAP3K8
mitogen-activated protein kinase kinase kinase 8
chr13_+_97874574 0.08 ENST00000343600.4
ENST00000345429.6
ENST00000376673.3
MBNL2
muscleblind-like splicing regulator 2
chr2_-_61108449 0.08 ENST00000439412.1
ENST00000452343.1
AC010733.4
AC010733.4
chr21_-_43373999 0.08 ENST00000380486.3
C2CD2
C2 calcium-dependent domain containing 2
chr19_+_42381173 0.08 ENST00000221972.3
CD79A
CD79a molecule, immunoglobulin-associated alpha
chr10_+_13142075 0.08 ENST00000378757.2
ENST00000430081.1
ENST00000378752.3
ENST00000378748.3
OPTN
optineurin
chr5_+_56469843 0.08 ENST00000514387.2
GPBP1
GC-rich promoter binding protein 1
chr2_+_163175394 0.08 ENST00000446271.1
ENST00000429691.2
GCA
grancalcin, EF-hand calcium binding protein
chr1_-_113249678 0.08 ENST00000369633.2
ENST00000425265.2
ENST00000369632.2
ENST00000436685.2
RHOC
ras homolog family member C
chr1_-_54304212 0.08 ENST00000540001.1
NDC1
NDC1 transmembrane nucleoporin
chr1_+_110453462 0.08 ENST00000488198.1
CSF1
colony stimulating factor 1 (macrophage)
chr12_-_323689 0.08 ENST00000428720.1
SLC6A12
solute carrier family 6 (neurotransmitter transporter), member 12
chr9_+_19230433 0.08 ENST00000434457.2
ENST00000602925.1
DENND4C
DENN/MADD domain containing 4C
chr18_-_12884259 0.08 ENST00000353319.4
ENST00000327283.3
PTPN2
protein tyrosine phosphatase, non-receptor type 2
chr4_-_103748880 0.08 ENST00000453744.2
ENST00000349311.8
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr1_-_166135952 0.08 ENST00000354422.3
FAM78B
family with sequence similarity 78, member B
chr20_+_18488137 0.08 ENST00000450074.1
ENST00000262544.2
ENST00000336714.3
ENST00000377475.3
SEC23B
Sec23 homolog B (S. cerevisiae)
chr4_-_5891918 0.07 ENST00000512574.1
CRMP1
collapsin response mediator protein 1
chr9_-_32526184 0.07 ENST00000545044.1
ENST00000379868.1
DDX58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr12_-_76425368 0.07 ENST00000602540.1
PHLDA1
pleckstrin homology-like domain, family A, member 1
chr5_+_56469939 0.07 ENST00000506184.2
GPBP1
GC-rich promoter binding protein 1
chr8_-_10987745 0.07 ENST00000400102.3
AF131215.5
AF131215.5
chr13_-_29069232 0.07 ENST00000282397.4
ENST00000541932.1
ENST00000539099.1
FLT1
fms-related tyrosine kinase 1
chr6_-_74230741 0.07 ENST00000316292.9
EEF1A1
eukaryotic translation elongation factor 1 alpha 1
chr3_+_157154578 0.07 ENST00000295927.3
PTX3
pentraxin 3, long
chr4_-_185395672 0.07 ENST00000393593.3
IRF2
interferon regulatory factor 2
chr1_+_63833261 0.07 ENST00000371108.4
ALG6
ALG6, alpha-1,3-glucosyltransferase
chr16_-_53737795 0.07 ENST00000262135.4
ENST00000564374.1
ENST00000566096.1
RPGRIP1L
RPGRIP1-like
chr3_+_141205852 0.07 ENST00000286364.3
ENST00000452898.1
RASA2
RAS p21 protein activator 2
chr1_-_36615051 0.07 ENST00000373163.1
TRAPPC3
trafficking protein particle complex 3
chr16_-_66959429 0.07 ENST00000420652.1
ENST00000299759.6
RRAD
Ras-related associated with diabetes
chr14_-_61190754 0.07 ENST00000216513.4
SIX4
SIX homeobox 4
chr19_+_45504688 0.07 ENST00000221452.8
ENST00000540120.1
ENST00000505236.1
RELB
v-rel avian reticuloendotheliosis viral oncogene homolog B
chr2_+_162016916 0.07 ENST00000405852.1
TANK
TRAF family member-associated NFKB activator
chr2_+_208394616 0.07 ENST00000432329.2
ENST00000353267.3
ENST00000445803.1
CREB1
cAMP responsive element binding protein 1
chr9_-_32526299 0.07 ENST00000379882.1
ENST00000379883.2
DDX58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr4_-_103749105 0.07 ENST00000394801.4
ENST00000394804.2
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr10_+_124739911 0.07 ENST00000405485.1
PSTK
phosphoseryl-tRNA kinase
chr9_+_127615733 0.07 ENST00000373574.1
WDR38
WD repeat domain 38
chr1_-_23694794 0.07 ENST00000374608.3
ZNF436
zinc finger protein 436
chr19_-_4338838 0.07 ENST00000594605.1
STAP2
signal transducing adaptor family member 2
chr22_-_37640277 0.07 ENST00000401529.3
ENST00000249071.6
RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr3_+_57261743 0.07 ENST00000288266.3
APPL1
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
chr14_+_96968707 0.07 ENST00000216277.8
ENST00000557320.1
ENST00000557471.1
PAPOLA
poly(A) polymerase alpha
chr3_+_101546827 0.07 ENST00000461724.1
ENST00000483180.1
ENST00000394054.2
NFKBIZ
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr8_+_21899898 0.07 ENST00000518533.1
ENST00000359441.3
FGF17
fibroblast growth factor 17
chr7_-_24797546 0.07 ENST00000414428.1
ENST00000419307.1
ENST00000342947.3
DFNA5
deafness, autosomal dominant 5
chr6_-_30712313 0.07 ENST00000376377.2
ENST00000259874.5
IER3
immediate early response 3
chr7_-_6066183 0.07 ENST00000422786.1
EIF2AK1
eukaryotic translation initiation factor 2-alpha kinase 1
chr7_-_93520259 0.06 ENST00000222543.5
TFPI2
tissue factor pathway inhibitor 2
chr7_+_134464414 0.06 ENST00000361901.2
CALD1
caldesmon 1
chr11_+_66025938 0.06 ENST00000394066.2
KLC2
kinesin light chain 2
chr9_+_36572851 0.06 ENST00000298048.2
ENST00000538311.1
ENST00000536987.1
ENST00000545008.1
ENST00000536860.1
ENST00000536329.1
ENST00000541717.1
ENST00000543751.1
MELK
maternal embryonic leucine zipper kinase
chr7_+_22766766 0.06 ENST00000426291.1
ENST00000401651.1
ENST00000258743.5
ENST00000420258.2
ENST00000407492.1
ENST00000401630.3
ENST00000406575.1
IL6
interleukin 6 (interferon, beta 2)
chr1_-_57889687 0.06 ENST00000371236.2
ENST00000371230.1
DAB1
Dab, reelin signal transducer, homolog 1 (Drosophila)
chr21_+_34775698 0.06 ENST00000381995.1
IFNGR2
interferon gamma receptor 2 (interferon gamma transducer 1)
chr19_+_42381337 0.06 ENST00000597454.1
ENST00000444740.2
CD79A
CD79a molecule, immunoglobulin-associated alpha
chr5_-_150466692 0.06 ENST00000315050.7
ENST00000523338.1
ENST00000522100.1
TNIP1
TNFAIP3 interacting protein 1
chr2_-_136743039 0.06 ENST00000537273.1
DARS
aspartyl-tRNA synthetase
chr11_-_790060 0.06 ENST00000330106.4
CEND1
cell cycle exit and neuronal differentiation 1
chrX_-_48827976 0.06 ENST00000218176.3
KCND1
potassium voltage-gated channel, Shal-related subfamily, member 1
chrX_-_119709637 0.06 ENST00000404115.3
CUL4B
cullin 4B
chr7_-_24797032 0.06 ENST00000409970.1
ENST00000409775.3
DFNA5
deafness, autosomal dominant 5
chr10_+_70320413 0.06 ENST00000373644.4
TET1
tet methylcytosine dioxygenase 1
chr1_-_1822495 0.06 ENST00000378609.4
GNB1
guanine nucleotide binding protein (G protein), beta polypeptide 1
chr22_-_37545972 0.06 ENST00000216223.5
IL2RB
interleukin 2 receptor, beta
chr11_-_72853091 0.06 ENST00000311172.7
ENST00000409314.1
FCHSD2
FCH and double SH3 domains 2
chr1_+_155657737 0.06 ENST00000471642.2
ENST00000471214.1
DAP3
death associated protein 3
chr5_-_141257954 0.06 ENST00000456271.1
ENST00000394536.3
ENST00000503492.1
ENST00000287008.3
PCDH1
protocadherin 1
chr2_+_233925064 0.06 ENST00000359570.5
ENST00000538935.1
INPP5D
inositol polyphosphate-5-phosphatase, 145kDa
chr4_-_103749313 0.06 ENST00000394803.5
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr17_-_61776522 0.06 ENST00000582055.1
LIMD2
LIM domain containing 2
chr2_-_136743169 0.06 ENST00000264161.4
DARS
aspartyl-tRNA synthetase
chrX_-_139015153 0.06 ENST00000370557.1
ATP11C
ATPase, class VI, type 11C
chr2_+_219745020 0.06 ENST00000258411.3
WNT10A
wingless-type MMTV integration site family, member 10A
chr9_-_127952187 0.06 ENST00000451402.1
ENST00000415905.1
PPP6C
protein phosphatase 6, catalytic subunit
chr15_+_57884086 0.06 ENST00000380569.2
ENST00000380561.2
ENST00000574161.1
ENST00000572390.1
ENST00000396180.1
ENST00000380560.2
GCOM1
GRINL1A complex locus 1
chr2_+_179059188 0.06 ENST00000392505.2
ENST00000359685.3
ENST00000357080.4
ENST00000409045.3
OSBPL6
oxysterol binding protein-like 6
chr3_+_111578027 0.06 ENST00000431670.2
ENST00000412622.1
PHLDB2
pleckstrin homology-like domain, family B, member 2
chr7_-_126892303 0.06 ENST00000358373.3
GRM8
glutamate receptor, metabotropic 8
chr3_+_5163905 0.06 ENST00000256496.3
ENST00000419534.2
ARL8B
ADP-ribosylation factor-like 8B
chr1_-_202129105 0.06 ENST00000367279.4
PTPN7
protein tyrosine phosphatase, non-receptor type 7
chr13_-_38443860 0.06 ENST00000426868.2
ENST00000379681.3
ENST00000338947.5
ENST00000355779.2
ENST00000358477.2
ENST00000379673.2
TRPC4
transient receptor potential cation channel, subfamily C, member 4
chr2_-_136743436 0.06 ENST00000441323.1
ENST00000449218.1
DARS
aspartyl-tRNA synthetase
chr19_-_9879293 0.06 ENST00000397902.2
ENST00000592859.1
ENST00000588267.1
ZNF846
zinc finger protein 846
chr12_+_49761273 0.06 ENST00000551540.1
ENST00000552918.1
ENST00000548777.1
ENST00000547865.1
ENST00000552171.1
SPATS2
spermatogenesis associated, serine-rich 2
chr12_+_72056773 0.06 ENST00000308086.2
THAP2
THAP domain containing, apoptosis associated protein 2
chr3_-_49131013 0.05 ENST00000424300.1
QRICH1
glutamine-rich 1
chr1_+_211432700 0.05 ENST00000452621.2
RCOR3
REST corepressor 3

Network of associatons between targets according to the STRING database.

First level regulatory network of RELA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0034148 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573) negative regulation of CD40 signaling pathway(GO:2000349)
0.1 0.3 GO:0090291 negative regulation of osteoclast proliferation(GO:0090291)
0.1 0.3 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.1 0.5 GO:0085032 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.1 0.2 GO:1990108 protein linear deubiquitination(GO:1990108)
0.1 0.2 GO:1903515 calcium ion transport from cytosol to endoplasmic reticulum(GO:1903515)
0.1 0.2 GO:0034343 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.1 0.2 GO:0071790 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.1 0.2 GO:0033386 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.1 0.3 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.1 0.3 GO:0002725 negative regulation of T cell cytokine production(GO:0002725)
0.1 0.5 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.0 0.2 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0 0.0 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.0 0.1 GO:0045083 negative regulation of interleukin-12 biosynthetic process(GO:0045083)
0.0 0.2 GO:0001827 inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828)
0.0 0.2 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.9 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 0.3 GO:1904550 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.0 0.4 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.3 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.0 0.3 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.0 0.1 GO:0042222 interleukin-1 biosynthetic process(GO:0042222) regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.0 0.1 GO:1902299 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.0 0.2 GO:0097056 selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
0.0 0.1 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.0 0.1 GO:0034476 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.0 0.1 GO:0032240 negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.0 0.2 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.0 0.1 GO:0001878 response to yeast(GO:0001878)
0.0 0.1 GO:1904530 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
0.0 0.1 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 0.1 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.0 0.1 GO:0045659 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.0 0.2 GO:0038033 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway(GO:0038033)
0.0 0.1 GO:0021589 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589) spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.0 0.1 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.0 0.1 GO:2000510 positive regulation of dendritic cell chemotaxis(GO:2000510)
0.0 0.4 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.4 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 0.1 GO:1903383 enzyme active site formation(GO:0018307) neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036482) detoxification of mercury ion(GO:0050787) positive regulation of superoxide dismutase activity(GO:1901671) positive regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902958) regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181) regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903383) negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903384) positive regulation of removal of superoxide radicals(GO:1904833)
0.0 0.0 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.0 0.1 GO:0042245 RNA repair(GO:0042245)
0.0 0.1 GO:1903281 protein transport into plasma membrane raft(GO:0044861) positive regulation of calcium:sodium antiporter activity(GO:1903281) positive regulation of potassium ion import(GO:1903288)
0.0 0.1 GO:0031296 B cell costimulation(GO:0031296)
0.0 0.1 GO:0072616 interleukin-18 secretion(GO:0072616)
0.0 0.1 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.1 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.1 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.0 0.1 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.1 GO:0033590 response to cobalamin(GO:0033590)
0.0 0.1 GO:0006447 regulation of translational initiation by iron(GO:0006447)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.0 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.0 0.3 GO:0002385 mucosal immune response(GO:0002385)
0.0 0.0 GO:0060265 positive regulation of respiratory burst involved in inflammatory response(GO:0060265)
0.0 0.1 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
0.0 0.0 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.0 0.1 GO:0000103 sulfate assimilation(GO:0000103)
0.0 0.3 GO:0016180 snRNA processing(GO:0016180)
0.0 0.1 GO:0001826 inner cell mass cell differentiation(GO:0001826)
0.0 0.1 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.0 0.1 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.8 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.0 0.1 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
0.1 0.2 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.0 0.6 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.3 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.1 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.0 0.2 GO:0005879 axonemal microtubule(GO:0005879)
0.0 0.4 GO:0060091 kinocilium(GO:0060091)
0.0 0.1 GO:1990423 Dsl1p complex(GO:0070939) RZZ complex(GO:1990423)
0.0 0.1 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.1 GO:0031906 late endosome lumen(GO:0031906)
0.0 0.3 GO:0032039 integrator complex(GO:0032039)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.1 GO:0043196 varicosity(GO:0043196)
0.0 0.2 GO:0042587 glycogen granule(GO:0042587)
0.0 0.2 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.0 GO:0043291 RAVE complex(GO:0043291)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 0.8 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 1.3 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 0.5 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.1 0.2 GO:0031775 lutropin-choriogonadotropic hormone receptor binding(GO:0031775) calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential(GO:0086039)
0.1 0.2 GO:0031862 prostanoid receptor binding(GO:0031862)
0.0 0.3 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.2 GO:0019981 interleukin-6 receptor activity(GO:0004915) leukemia inhibitory factor receptor activity(GO:0004923) interleukin-6 binding(GO:0019981)
0.0 0.2 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.0 0.3 GO:1990763 arrestin family protein binding(GO:1990763)
0.0 0.2 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0 0.2 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.3 GO:0016015 morphogen activity(GO:0016015)
0.0 0.1 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.0 0.1 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.0 0.1 GO:0019976 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.0 0.1 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0 0.1 GO:0004020 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.1 GO:0097677 STAT family protein binding(GO:0097677)
0.0 0.0 GO:0050473 arachidonate 15-lipoxygenase activity(GO:0050473)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.1 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.0 0.1 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.1 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.1 GO:0035514 DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.1 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.3 GO:0070628 proteasome binding(GO:0070628)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.9 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.1 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.1 GO:0019237 centromeric DNA binding(GO:0019237)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.1 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.2 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.2 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.3 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.4 PID LPA4 PATHWAY LPA4-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.3 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.6 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 1.9 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.2 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.2 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.3 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.1 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease