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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for RFX3_RFX2

Z-value: 1.28

Motif logo

Transcription factors associated with RFX3_RFX2

Gene Symbol Gene ID Gene Info
ENSG00000080298.11 regulatory factor X3
ENSG00000087903.8 regulatory factor X2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RFX3hg19_v2_chr9_-_3489406_34894160.955.1e-02Click!
RFX2hg19_v2_chr19_-_6110555_6110617-0.811.9e-01Click!

Activity profile of RFX3_RFX2 motif

Sorted Z-values of RFX3_RFX2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chrX_-_48693955 1.46 ENST00000218230.5
proprotein convertase subtilisin/kexin type 1 inhibitor
chr2_-_74648702 1.42 ENST00000518863.1
chromosome 2 open reading frame 81
chr19_-_59084647 1.31 ENST00000594234.1
ENST00000596039.1
myeloid zinc finger 1
chr12_-_64062583 0.72 ENST00000542209.1
dpy-19-like 2 (C. elegans)
chr19_-_51017881 0.71 ENST00000601207.1
ENST00000598657.1
ENST00000376916.3
aspartate dehydrogenase domain containing
chr4_+_147096837 0.68 ENST00000296581.5
ENST00000502781.1
LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr15_-_52971544 0.67 ENST00000566768.1
ENST00000561543.1
family with sequence similarity 214, member A
chr19_-_58892389 0.65 ENST00000427624.2
ENST00000597582.1
zinc finger protein 837
chr16_-_30773372 0.65 ENST00000545825.1
ENST00000541260.1
chromosome 16 open reading frame 93
chr19_+_1261106 0.64 ENST00000588411.1
cold inducible RNA binding protein
chr19_-_59084922 0.63 ENST00000215057.2
ENST00000599369.1
myeloid zinc finger 1
chr19_+_17413663 0.59 ENST00000594999.1
mitochondrial ribosomal protein L34
chr10_+_104178946 0.57 ENST00000432590.1
F-box and leucine-rich repeat protein 15
chr19_-_7553889 0.55 ENST00000221480.1
peroxisomal biogenesis factor 11 gamma
chr11_-_64885111 0.54 ENST00000528598.1
ENST00000310597.4
zinc finger, HIT-type containing 2
chr19_-_17356697 0.54 ENST00000291442.3
nuclear receptor subfamily 2, group F, member 6
chr22_-_38349552 0.53 ENST00000422191.1
ENST00000249079.2
ENST00000418863.1
ENST00000403305.1
ENST00000403026.1
chromosome 22 open reading frame 23
chr3_-_42003613 0.51 ENST00000414606.1
unc-51 like kinase 4
chr1_+_161068179 0.48 ENST00000368011.4
ENST00000392192.2
kelch domain containing 9
chr19_+_5681153 0.48 ENST00000579559.1
ENST00000577222.1
hydroxysteroid (11-beta) dehydrogenase 1-like
ribosomal protein L36
chr9_+_131085095 0.47 ENST00000372875.3
coenzyme Q4
chr19_-_7553852 0.47 ENST00000593547.1
peroxisomal biogenesis factor 11 gamma
chr17_+_38375528 0.46 ENST00000583268.1
WAS/WASL interacting protein family, member 2
chr19_-_55791058 0.45 ENST00000587959.1
ENST00000585927.1
ENST00000587922.1
ENST00000585698.1
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr5_+_61708488 0.45 ENST00000505902.1
importin 11
chr3_-_118753792 0.45 ENST00000480431.1
immunoglobulin superfamily, member 11
chr14_+_78227105 0.44 ENST00000439131.2
ENST00000355883.3
ENST00000557011.1
ENST00000556047.1
chromosome 14 open reading frame 178
chr2_+_74682150 0.43 ENST00000233331.7
ENST00000431187.1
ENST00000409917.1
ENST00000409493.2
INO80 complex subunit B
chr11_-_57089774 0.43 ENST00000527207.1
tankyrase 1 binding protein 1, 182kDa
chr19_+_18530184 0.42 ENST00000601357.2
single stranded DNA binding protein 4
chr6_-_43484621 0.41 ENST00000506469.1
ENST00000503972.1
Yip1 domain family, member 3
chr19_+_58962971 0.41 ENST00000336614.4
ENST00000545523.1
ENST00000599194.1
ENST00000598244.1
ENST00000599193.1
ENST00000594214.1
ENST00000391696.1
zinc finger protein 324B
chr10_-_103347883 0.41 ENST00000339310.3
ENST00000370158.3
ENST00000299206.4
ENST00000456836.2
ENST00000413344.1
ENST00000429502.1
ENST00000430045.1
ENST00000370172.1
ENST00000436284.2
ENST00000370162.3
polymerase (DNA directed), lambda
chr11_+_66360665 0.40 ENST00000310190.4
copper chaperone for superoxide dismutase
chr9_+_136325089 0.40 ENST00000291722.7
ENST00000316948.4
ENST00000540581.1
calcium channel flower domain containing 1
chr17_-_8079632 0.40 ENST00000431792.2
transmembrane protein 107
chr22_-_38240316 0.40 ENST00000411961.2
ENST00000434930.1
ankyrin repeat domain 54
chr11_+_537494 0.40 ENST00000270115.7
leucine rich repeat containing 56
chr11_+_844406 0.40 ENST00000397404.1
tetraspanin 4
chr12_+_48577366 0.40 ENST00000316554.3
chromosome 12 open reading frame 68
chr19_+_50529329 0.39 ENST00000599155.1
zinc finger protein 473
chr1_-_16563641 0.38 ENST00000375599.3
REM2 and RAB-like small GTPase 1
chr16_+_57662527 0.38 ENST00000563374.1
ENST00000568234.1
ENST00000565770.1
ENST00000564338.1
ENST00000566164.1
G protein-coupled receptor 56
chr9_+_35829208 0.37 ENST00000439587.2
ENST00000377991.4
transmembrane protein 8B
chr12_-_110486281 0.36 ENST00000546627.1
chromosome 12 open reading frame 76
chr5_-_54529415 0.36 ENST00000282572.4
cyclin O
chr19_+_1450112 0.36 ENST00000590469.1
ENST00000233607.2
ENST00000238483.4
ENST00000590877.1
adenomatosis polyposis coli 2
chr2_+_220462560 0.35 ENST00000456909.1
ENST00000295641.10
serine/threonine kinase 11 interacting protein
chr16_+_30671223 0.35 ENST00000568722.1
fibrosin
chr17_-_7761256 0.35 ENST00000575208.1
LSM domain containing 1
chr19_-_41870026 0.35 ENST00000243578.3
B9 protein domain 2
chr16_+_57662596 0.34 ENST00000567397.1
ENST00000568979.1
G protein-coupled receptor 56
chr4_+_141445333 0.34 ENST00000507667.1
ELMO/CED-12 domain containing 2
chr1_-_156571254 0.34 ENST00000438976.2
ENST00000334588.7
ENST00000368232.4
ENST00000415314.2
G patch domain containing 4
chr16_-_67450325 0.34 ENST00000348579.2
zinc finger, DHHC-type containing 1
chr22_-_38240412 0.33 ENST00000215941.4
ankyrin repeat domain 54
chr19_-_40324767 0.33 ENST00000601972.1
ENST00000430012.2
ENST00000323039.5
ENST00000348817.3
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
chr12_+_4671352 0.33 ENST00000542744.1
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
chr20_+_43992094 0.33 ENST00000453003.1
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
chr5_+_176873789 0.33 ENST00000323249.3
ENST00000502922.1
proline rich 7 (synaptic)
chr11_-_27384737 0.32 ENST00000317945.6
coiled-coil domain containing 34
chr1_+_179051160 0.32 ENST00000367625.4
ENST00000352445.6
torsin family 3, member A
chr2_+_219221573 0.32 ENST00000289388.3
chromosome 2 open reading frame 62
chr11_-_75379479 0.32 ENST00000434603.2
microtubule-associated protein 6
chr17_-_61523622 0.31 ENST00000448884.2
ENST00000582297.1
ENST00000582034.1
ENST00000578072.1
ENST00000360793.3
cytochrome b561
chrX_+_102024075 0.31 ENST00000431616.1
ENST00000440496.1
ENST00000420471.1
ENST00000435966.1
long intergenic non-protein coding RNA 630
chr1_-_167905225 0.31 ENST00000367846.4
mitochondrial pyruvate carrier 2
chr22_+_30752606 0.31 ENST00000399824.2
ENST00000405659.1
ENST00000338306.3
coiled-coil domain containing 157
chr11_-_8615720 0.30 ENST00000358872.3
ENST00000454443.2
serine/threonine kinase 33
chr2_+_159651821 0.30 ENST00000309950.3
ENST00000409042.1
death associated protein-like 1
chr12_+_6930964 0.30 ENST00000382315.3
G protein-coupled receptor 162
chr3_+_187420101 0.30 ENST00000449623.1
ENST00000437407.1
Uncharacterized protein
chr16_+_30773610 0.30 ENST00000566811.1
ring finger protein 40, E3 ubiquitin protein ligase
chr9_-_130497565 0.30 ENST00000336067.6
ENST00000373281.5
ENST00000373284.5
ENST00000458505.3
torsin family 2, member A
chr14_+_105992906 0.30 ENST00000392519.2
transmembrane protein 121
chr19_+_50879705 0.29 ENST00000598168.1
ENST00000411902.2
ENST00000253727.5
ENST00000597790.1
ENST00000597130.1
ENST00000599105.1
nuclear receptor subfamily 1, group H, member 2
chr21_-_43916433 0.29 ENST00000291536.3
radial spoke head 1 homolog (Chlamydomonas)
chr19_+_18530146 0.29 ENST00000348495.6
ENST00000270061.7
single stranded DNA binding protein 4
chr6_-_43484718 0.28 ENST00000372422.2
Yip1 domain family, member 3
chr7_-_156433195 0.28 ENST00000333319.6
chromosome 7 open reading frame 13
chr12_-_2966193 0.28 ENST00000382678.3
Uncharacterized protein ENSP00000372125
chr1_+_43637996 0.28 ENST00000528956.1
ENST00000529956.1
WD repeat domain 65
chr19_+_9945962 0.28 ENST00000587625.1
ENST00000247970.4
ENST00000588695.1
peptidylprolyl cis/trans isomerase, NIMA-interacting 1
chr17_-_41322332 0.28 ENST00000590740.1
RP11-242D8.1
chr6_+_30848740 0.28 ENST00000505534.1
discoidin domain receptor tyrosine kinase 1
chr6_+_31939608 0.27 ENST00000375331.2
ENST00000375333.2
serine/threonine kinase 19
chr17_+_1944790 0.27 ENST00000575162.1
diphthamide biosynthesis 1
chr22_-_31063782 0.26 ENST00000404885.1
ENST00000403268.1
ENST00000407308.1
ENST00000342474.4
ENST00000334679.3
dual specificity phosphatase 18
chrX_+_153146127 0.26 ENST00000452593.1
ENST00000357566.1
Putative lung carcinoma-associated protein 10
chr19_+_19639670 0.26 ENST00000436027.5
YjeF N-terminal domain containing 3
chr19_-_6393216 0.26 ENST00000595047.1
general transcription factor IIF, polypeptide 1, 74kDa
chr1_+_161129240 0.26 ENST00000492950.1
ubiquitin specific peptidase 21
chr8_+_144798429 0.26 ENST00000338033.4
ENST00000395107.4
ENST00000395108.2
mitogen-activated protein kinase 15
chr19_-_46974741 0.26 ENST00000313683.10
ENST00000602246.1
paraneoplastic Ma antigen family-like 1
chr7_+_73275483 0.26 ENST00000320531.2
Williams-Beuren syndrome chromosome region 28
chr7_-_1177874 0.26 ENST00000397098.3
ENST00000357429.6
ENST00000397100.2
ENST00000491163.1
chromosome 7 open reading frame 50
chr11_+_61447845 0.25 ENST00000257215.5
diacylglycerol lipase, alpha
chr9_-_131418944 0.25 ENST00000419989.1
ENST00000451652.1
ENST00000372715.2
WD repeat domain 34
chr17_-_7760779 0.25 ENST00000335155.5
ENST00000575071.1
LSM domain containing 1
chr19_-_7990991 0.24 ENST00000318978.4
cortexin 1
chr17_+_6544078 0.24 ENST00000250101.5
thioredoxin domain containing 17
chr6_+_30848771 0.24 ENST00000503180.1
discoidin domain receptor tyrosine kinase 1
chr7_+_102073966 0.24 ENST00000495936.1
ENST00000356387.2
ENST00000478730.2
ENST00000468241.1
ENST00000403646.3
ORAI calcium release-activated calcium modulator 2
chr19_+_56652556 0.24 ENST00000337080.3
zinc finger protein 444
chr7_+_150725510 0.24 ENST00000461373.1
ENST00000358849.4
ENST00000297504.6
ENST00000542328.1
ENST00000498578.1
ENST00000356058.4
ENST00000477719.1
ENST00000477092.1
ATP-binding cassette, sub-family B (MDR/TAP), member 8
chr14_-_74181106 0.24 ENST00000316836.3
paraneoplastic Ma antigen 1
chr3_+_149192475 0.24 ENST00000465758.1
transmembrane 4 L six family member 4
chr7_+_150065278 0.24 ENST00000519397.1
ENST00000479668.1
ENST00000540729.1
replication initiator 1
chr17_-_73840614 0.24 ENST00000586108.1
unc-13 homolog D (C. elegans)
chr19_-_5680499 0.23 ENST00000587589.1
chromosome 19 open reading frame 70
chr19_-_5680891 0.23 ENST00000309324.4
chromosome 19 open reading frame 70
chr8_-_101964738 0.23 ENST00000523938.1
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr1_-_21978312 0.23 ENST00000359708.4
ENST00000290101.4
RAP1 GTPase activating protein
chr2_-_203735586 0.23 ENST00000454326.1
ENST00000432273.1
ENST00000450143.1
ENST00000411681.1
islet cell autoantigen 1,69kDa-like
chr11_-_67271723 0.23 ENST00000533391.1
ENST00000534749.1
ENST00000532703.1
phosphatidylinositol transfer protein, membrane-associated 1
chr19_-_1490398 0.23 ENST00000588671.1
ENST00000300954.5
proprotein convertase subtilisin/kexin type 4
chr19_+_56165480 0.23 ENST00000450554.2
U2 small nuclear RNA auxiliary factor 2
chr7_+_150065879 0.23 ENST00000397281.2
ENST00000444957.1
ENST00000466559.1
ENST00000489432.2
ENST00000475514.1
ENST00000482680.1
ENST00000488943.1
ENST00000518514.1
ENST00000478789.1
replication initiator 1
zinc finger protein 775
chr6_+_144980954 0.23 ENST00000367525.3
utrophin
chr7_+_100797678 0.23 ENST00000337619.5
adaptor-related protein complex 1, sigma 1 subunit
chr14_+_24025345 0.23 ENST00000557630.1
thiamine triphosphatase
chr1_+_45274154 0.22 ENST00000450269.1
ENST00000453418.1
ENST00000409335.2
BTB (POZ) domain containing 19
chr19_-_633576 0.22 ENST00000588649.2
polymerase (RNA) mitochondrial (DNA directed)
chr7_+_99699179 0.22 ENST00000438383.1
ENST00000429084.1
ENST00000359593.4
ENST00000439416.1
adaptor-related protein complex 4, mu 1 subunit
chr6_+_30848557 0.22 ENST00000460944.2
ENST00000324771.8
discoidin domain receptor tyrosine kinase 1
chr17_+_6544356 0.22 ENST00000574838.1
thioredoxin domain containing 17
chr16_-_30064244 0.22 ENST00000571269.1
ENST00000561666.1
family with sequence similarity 57, member B
chr6_+_30848829 0.22 ENST00000508317.1
discoidin domain receptor tyrosine kinase 1
chr19_+_55851221 0.22 ENST00000255613.3
ENST00000539076.1
suppressor of variegation 4-20 homolog 2 (Drosophila)
Uncharacterized protein
chr11_-_66104237 0.22 ENST00000530056.1
Ras and Rab interactor 1
chr19_+_56652643 0.22 ENST00000586123.1
zinc finger protein 444
chr17_+_26662679 0.21 ENST00000578158.1
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr1_-_156217829 0.21 ENST00000356983.2
ENST00000335852.1
ENST00000340183.5
ENST00000540423.1
progestin and adipoQ receptor family member VI
chr1_-_36916066 0.21 ENST00000315643.9
organic solute carrier partner 1
chr1_+_155178481 0.21 ENST00000368376.3
metaxin 1
chr3_-_129147432 0.21 ENST00000503957.1
ENST00000505956.1
ENST00000326085.3
EF-hand calcium binding domain 12
chr16_-_54963026 0.21 ENST00000560208.1
ENST00000557792.1
colorectal neoplasia differentially expressed (non-protein coding)
chr19_+_14063278 0.21 ENST00000254337.6
DDB1 and CUL4 associated factor 15
chr19_-_46405861 0.21 ENST00000322217.5
Myb-related transcription factor, partner of profilin
chrX_+_103173457 0.20 ENST00000419165.1
thymosin beta 15B
chr22_-_50746027 0.20 ENST00000425954.1
ENST00000449103.1
plexin B2
chr3_-_10052849 0.20 ENST00000437616.1
ENST00000429065.2
AC022007.5
chr9_+_131084846 0.20 ENST00000608951.1
coenzyme Q4
chr19_+_19639704 0.20 ENST00000514277.4
YjeF N-terminal domain containing 3
chr1_+_44457261 0.20 ENST00000372318.3
coiled-coil domain containing 24
chr16_+_28986134 0.20 ENST00000352260.7
spinster homolog 1 (Drosophila)
chr20_+_42984330 0.20 ENST00000316673.4
ENST00000609795.1
ENST00000457232.1
ENST00000609262.1
hepatocyte nuclear factor 4, alpha
chr17_-_7761172 0.20 ENST00000333775.5
ENST00000575771.1
LSM domain containing 1
chr1_+_74663994 0.20 ENST00000472069.1
fucose-1-phosphate guanylyltransferase
chr11_+_66278080 0.20 ENST00000318312.7
ENST00000526815.1
ENST00000537537.1
ENST00000525809.1
ENST00000455748.2
ENST00000393994.2
Bardet-Biedl syndrome 1
chr5_+_121647877 0.20 ENST00000514497.2
ENST00000261367.7
synuclein, alpha interacting protein
chr3_-_107941209 0.20 ENST00000492106.1
intraflagellar transport 57 homolog (Chlamydomonas)
chr19_-_42759300 0.20 ENST00000222329.4
Ets2 repressor factor
chr2_-_130902567 0.20 ENST00000457413.1
ENST00000392984.3
ENST00000409128.1
ENST00000441670.1
ENST00000409943.3
ENST00000409234.3
ENST00000310463.6
coiled-coil domain containing 74B
chr21_-_44846999 0.20 ENST00000270162.6
salt-inducible kinase 1
chr16_+_30772913 0.19 ENST00000563909.1
ring finger protein 40, E3 ubiquitin protein ligase
chr10_-_135150367 0.19 ENST00000368555.3
ENST00000252939.4
ENST00000368558.1
ENST00000368556.2
calcyon neuron-specific vesicular protein
chr7_+_102389434 0.19 ENST00000409231.3
ENST00000418198.1
family with sequence similarity 185, member A
chr11_-_57089671 0.19 ENST00000532437.1
tankyrase 1 binding protein 1, 182kDa
chr1_+_183605200 0.19 ENST00000304685.4
ral guanine nucleotide dissociation stimulator-like 1
chr19_-_58874112 0.19 ENST00000311044.3
ENST00000595763.1
ENST00000425453.3
zinc finger protein 497
chr3_-_49761337 0.19 ENST00000535833.1
ENST00000308388.6
ENST00000480687.1
ENST00000308375.6
adhesion molecule with Ig-like domain 3
GDP-mannose pyrophosphorylase B
chr12_+_56511943 0.19 ENST00000257940.2
ENST00000552345.1
ENST00000551880.1
ENST00000546903.1
ENST00000551790.1
zinc finger CCCH-type containing 10
extended synaptotagmin-like protein 1
chr14_+_105941118 0.19 ENST00000550577.1
ENST00000538259.2
cysteine-rich protein 2
chr19_+_54371114 0.19 ENST00000448420.1
ENST00000439000.1
ENST00000391770.4
ENST00000391771.1
myeloid-associated differentiation marker
chr11_-_61129723 0.19 ENST00000537680.1
ENST00000426130.2
ENST00000294072.4
cytochrome b561 family, member A3
chr19_-_40950182 0.19 ENST00000596456.1
SERTA domain containing 3
chr6_+_35227449 0.19 ENST00000373953.3
ENST00000440666.2
ENST00000339411.5
zinc finger protein 76
chr22_+_30752963 0.18 ENST00000445005.1
ENST00000430839.1
coiled-coil domain containing 157
chr15_-_68497657 0.18 ENST00000448060.2
ENST00000467889.1
calmodulin-like 4
chr19_-_58919815 0.18 ENST00000597980.1
CTD-2619J13.14
chr19_-_47249679 0.18 ENST00000263280.6
striatin, calmodulin binding protein 4
chr12_+_7014126 0.18 ENST00000415834.1
ENST00000436789.1
leucine rich repeat containing 23
chr11_-_559377 0.18 ENST00000486629.1
chromosome 11 open reading frame 35
chr18_+_77905794 0.18 ENST00000587254.1
ENST00000586421.1
Uncharacterized protein
chr2_+_27193480 0.18 ENST00000233121.2
ENST00000405074.3
microtubule-associated protein, RP/EB family, member 3
chr8_+_38243821 0.18 ENST00000519476.2
leucine zipper-EF-hand containing transmembrane protein 2
chr2_+_220144168 0.18 ENST00000392087.2
ENST00000442681.1
ENST00000439026.1
DnaJ (Hsp40) homolog, subfamily B, member 2
chr16_-_57836321 0.18 ENST00000569112.1
ENST00000562311.1
ENST00000445690.2
ENST00000379655.4
kinesin family member C3
chr19_-_50370799 0.18 ENST00000600910.1
ENST00000322344.3
ENST00000600573.1
polynucleotide kinase 3'-phosphatase
chr9_-_131085021 0.18 ENST00000372890.4
TruB pseudouridine (psi) synthase family member 2
chr16_-_71264558 0.17 ENST00000448089.2
ENST00000393550.2
ENST00000448691.1
ENST00000393567.2
ENST00000321489.5
ENST00000539973.1
ENST00000288168.10
ENST00000545267.1
ENST00000541601.1
ENST00000538248.1
HYDIN, axonemal central pair apparatus protein
chr17_+_4736627 0.17 ENST00000355280.6
ENST00000347992.7
misshapen-like kinase 1
chr6_-_31940065 0.17 ENST00000375349.3
ENST00000337523.5
decapping exoribonuclease
chr22_+_41601209 0.17 ENST00000216237.5
l(3)mbt-like 2 (Drosophila)
chr22_-_33968239 0.17 ENST00000452586.2
ENST00000421768.1
like-glycosyltransferase
chr17_+_78389247 0.17 ENST00000520136.2
ENST00000520284.1
ENST00000517795.1
ENST00000523228.1
ENST00000523828.1
ENST00000522200.1
ENST00000521565.1
ENST00000518907.1
ENST00000518644.1
ENST00000518901.1
endonuclease V
chr19_+_35630628 0.17 ENST00000588715.1
ENST00000588607.1
FXYD domain containing ion transport regulator 1
chr5_-_142065612 0.17 ENST00000360966.5
ENST00000411960.1
fibroblast growth factor 1 (acidic)
chr21_+_18885318 0.17 ENST00000400166.1
coxsackie virus and adenovirus receptor
chr16_-_88923285 0.17 ENST00000542788.1
ENST00000569433.1
ENST00000268695.5
ENST00000568311.1
galactosamine (N-acetyl)-6-sulfate sulfatase
chr15_+_42066888 0.17 ENST00000510535.1
mitogen-activated protein kinase binding protein 1
chr8_-_135725205 0.17 ENST00000523399.1
ENST00000377838.3
zinc finger and AT hook domain containing
chr19_-_51289436 0.17 ENST00000562076.1
CTD-2568A17.1
chr12_-_110486348 0.17 ENST00000547573.1
ENST00000546651.2
ENST00000551185.2
chromosome 12 open reading frame 76
chr18_+_44526786 0.16 ENST00000245121.5
ENST00000356157.7
katanin p60 subunit A-like 2
chr7_+_99699280 0.16 ENST00000421755.1
adaptor-related protein complex 4, mu 1 subunit
chr2_-_203736452 0.16 ENST00000419460.1
islet cell autoantigen 1,69kDa-like
chr17_-_8079648 0.16 ENST00000449985.2
ENST00000532998.1
ENST00000437139.2
ENST00000533070.1
ENST00000316425.5
transmembrane protein 107
chr15_-_55790515 0.16 ENST00000448430.2
ENST00000457155.2
dyslexia susceptibility 1 candidate 1

Network of associatons between targets according to the STRING database.

First level regulatory network of RFX3_RFX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.1 0.4 GO:0015680 intracellular copper ion transport(GO:0015680)
0.1 0.4 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.1 0.9 GO:0044375 regulation of peroxisome size(GO:0044375)
0.1 0.6 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.1 0.3 GO:0090340 positive regulation of high-density lipoprotein particle assembly(GO:0090108) positive regulation of pancreatic juice secretion(GO:0090187) positive regulation of secretion of lysosomal enzymes(GO:0090340)
0.1 0.3 GO:0098502 DNA dephosphorylation(GO:0098502)
0.1 0.5 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.1 0.6 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.1 0.3 GO:0002432 granuloma formation(GO:0002432)
0.1 0.2 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
0.1 0.3 GO:0006850 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.1 0.3 GO:0045013 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.1 0.4 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.1 0.7 GO:0018406 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.1 0.6 GO:2001166 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.1 0.3 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.1 0.3 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.1 0.2 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.1 0.2 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.1 0.2 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425)
0.1 1.0 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.1 GO:0070376 regulation of ERK5 cascade(GO:0070376) negative regulation of ERK5 cascade(GO:0070377)
0.0 0.2 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.1 GO:1901382 chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
0.0 1.5 GO:0002021 response to dietary excess(GO:0002021)
0.0 0.2 GO:1904636 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.0 0.3 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
0.0 0.2 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.0 0.2 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.0 0.2 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.0 0.1 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0 0.2 GO:0042246 tissue regeneration(GO:0042246)
0.0 0.8 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.2 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.5 GO:0050961 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0 0.1 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0 0.1 GO:0061568 dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
0.0 0.1 GO:0002663 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.0 0.3 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.1 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.0 0.1 GO:0061009 common bile duct development(GO:0061009)
0.0 0.1 GO:1904398 positive regulation of neuromuscular junction development(GO:1904398)
0.0 0.2 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.0 0.4 GO:0015886 heme transport(GO:0015886)
0.0 0.3 GO:0061051 positive regulation of cell growth involved in cardiac muscle cell development(GO:0061051)
0.0 0.2 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 0.2 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.0 0.5 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.1 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.1 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.1 GO:0060278 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.0 0.1 GO:0030573 bile acid catabolic process(GO:0030573)
0.0 0.1 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.0 0.4 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.0 0.1 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.6 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.2 GO:2000544 cell chemotaxis to fibroblast growth factor(GO:0035766) endothelial cell chemotaxis to fibroblast growth factor(GO:0035768) regulation of cell chemotaxis to fibroblast growth factor(GO:1904847) regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000544)
0.0 0.2 GO:0097338 response to clozapine(GO:0097338)
0.0 0.2 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
0.0 0.2 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.5 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.6 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.0 0.1 GO:0072334 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.0 0.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.1 GO:0097113 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.0 0.6 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 0.2 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.0 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.1 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.0 0.1 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.1 GO:0009956 radial pattern formation(GO:0009956)
0.0 0.1 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.0 0.2 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.1 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.1 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.1 GO:0000432 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
0.0 0.2 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.2 GO:0050884 neuromuscular process controlling posture(GO:0050884)
0.0 0.2 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.2 GO:1901978 mitochondrial fragmentation involved in apoptotic process(GO:0043653) positive regulation of cell cycle checkpoint(GO:1901978)
0.0 0.0 GO:0070434 positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434)
0.0 0.0 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.0 0.2 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.1 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.1 GO:0010731 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.0 0.1 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.1 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.2 GO:1990716 axonemal central apparatus(GO:1990716)
0.1 0.2 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.1 0.6 GO:0033503 HULC complex(GO:0033503)
0.1 0.2 GO:0044609 DBIRD complex(GO:0044609)
0.1 0.7 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.1 GO:0001534 radial spoke(GO:0001534)
0.0 0.4 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.3 GO:0043196 varicosity(GO:0043196)
0.0 0.7 GO:0036038 MKS complex(GO:0036038)
0.0 0.5 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.2 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.2 GO:0089701 U2AF(GO:0089701)
0.0 0.5 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.1 GO:1990032 parallel fiber(GO:1990032)
0.0 0.9 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.2 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.3 GO:0034464 BBSome(GO:0034464)
0.0 0.1 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.1 GO:1990031 pinceau fiber(GO:1990031)
0.0 0.4 GO:0016342 catenin complex(GO:0016342)
0.0 0.1 GO:0097598 sperm cytoplasmic droplet(GO:0097598)
0.0 0.3 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.2 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.5 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.2 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.1 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.4 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.1 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.2 GO:0070938 contractile ring(GO:0070938)
0.0 0.2 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.2 GO:0032797 SMN complex(GO:0032797)
0.0 0.0 GO:1990812 growth cone filopodium(GO:1990812)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.1 GO:0033263 CORVET complex(GO:0033263)
0.0 0.4 GO:0097431 mitotic spindle pole(GO:0097431)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0052857 NADHX epimerase activity(GO:0052856) NADPHX epimerase activity(GO:0052857)
0.2 0.5 GO:0050333 thiamin-triphosphatase activity(GO:0050333)
0.1 0.4 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.1 0.4 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.1 0.3 GO:0001133 RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding(GO:0001133)
0.1 0.3 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.1 0.4 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.1 0.2 GO:0008158 hedgehog receptor activity(GO:0008158)
0.1 0.3 GO:0051733 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.1 1.0 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 0.6 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 0.2 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.1 0.2 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
0.0 0.6 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.3 GO:0070568 guanylyltransferase activity(GO:0070568)
0.0 0.4 GO:0097506 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0 0.2 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.0 0.3 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.0 0.4 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.1 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 0.3 GO:0050815 phosphoserine binding(GO:0050815) phosphothreonine binding(GO:0050816)
0.0 0.4 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.1 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.0 0.1 GO:0070984 SET domain binding(GO:0070984)
0.0 0.5 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.3 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.2 GO:0005119 smoothened binding(GO:0005119)
0.0 0.1 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.2 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.8 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.0 0.2 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.1 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.1 GO:0070736 protein-glycine ligase activity, initiating(GO:0070736)
0.0 0.8 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.5 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.1 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.0 0.1 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.0 0.2 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.1 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.2 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.2 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.2 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.1 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.2 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.3 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.3 GO:0070513 death domain binding(GO:0070513)
0.0 0.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.1 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 1.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0051400 BH domain binding(GO:0051400)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.1 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.0 GO:0052839 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.0 0.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.4 GO:0004707 MAP kinase activity(GO:0004707)
0.0 2.3 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.2 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.3 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.3 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.3 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.2 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 1.1 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.2 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors