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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for RUNX1_RUNX2

Z-value: 0.74

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Transcription factors associated with RUNX1_RUNX2

Gene Symbol Gene ID Gene Info
ENSG00000159216.14 RUNX family transcription factor 1
ENSG00000124813.16 RUNX family transcription factor 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RUNX2hg19_v2_chr6_+_45296048_45296106-0.995.7e-03Click!
RUNX1hg19_v2_chr21_-_36421401_36421462-0.982.4e-02Click!

Activity profile of RUNX1_RUNX2 motif

Sorted Z-values of RUNX1_RUNX2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_+_73780852 0.61 ENST00000589666.1
unkempt family zinc finger
chr17_+_75316336 0.54 ENST00000591934.1
septin 9
chr14_-_81425828 0.47 ENST00000555529.1
ENST00000556042.1
ENST00000556981.1
centrosomal protein 128kDa
chr19_+_54495542 0.46 ENST00000252729.2
ENST00000352529.1
calcium channel, voltage-dependent, gamma subunit 6
chr6_+_24126350 0.42 ENST00000378491.4
ENST00000378478.1
ENST00000378477.2
neurensin 1
chr19_-_55895966 0.41 ENST00000444469.3
transmembrane protein 238
chr11_+_2923423 0.38 ENST00000312221.5
solute carrier family 22, member 18
chr1_+_179051160 0.37 ENST00000367625.4
ENST00000352445.6
torsin family 3, member A
chr5_-_108063949 0.37 ENST00000606054.1
long intergenic non-protein coding RNA 1023
chr11_+_2923499 0.36 ENST00000449793.2
solute carrier family 22, member 18
chr11_-_64885111 0.35 ENST00000528598.1
ENST00000310597.4
zinc finger, HIT-type containing 2
chr4_-_140223614 0.34 ENST00000394223.1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr6_+_31515337 0.34 ENST00000376148.4
ENST00000376145.4
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
chr19_+_3708338 0.31 ENST00000590545.1
tight junction protein 3
chr6_+_31514622 0.31 ENST00000376146.4
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
chr12_-_58027138 0.31 ENST00000341156.4
beta-1,4-N-acetyl-galactosaminyl transferase 1
chr6_+_36646435 0.31 ENST00000244741.5
ENST00000405375.1
ENST00000373711.2
cyclin-dependent kinase inhibitor 1A (p21, Cip1)
chr15_-_44069513 0.29 ENST00000433927.1
elongation factor RNA polymerase II-like 3
chr4_+_76649753 0.29 ENST00000603759.1
USO1 vesicle transport factor
chr2_+_242498135 0.29 ENST00000318407.3
BCL2-related ovarian killer
chr19_-_6415695 0.28 ENST00000594496.1
ENST00000594745.1
ENST00000600480.1
KH-type splicing regulatory protein
chr17_+_19281787 0.28 ENST00000482850.1
mitogen-activated protein kinase 7
chr19_-_36233332 0.27 ENST00000592537.1
ENST00000246532.1
ENST00000344990.3
ENST00000588992.1
IGF-like family receptor 1
chr17_+_73455788 0.27 ENST00000581519.1
KIAA0195
chr7_-_44105158 0.27 ENST00000297283.3
phosphoglycerate mutase 2 (muscle)
chr19_-_30199516 0.27 ENST00000591243.1
chromosome 19 open reading frame 12
chr11_-_117699413 0.26 ENST00000528014.1
FXYD domain containing ion transport regulator 2
chr22_+_21996549 0.26 ENST00000248958.4
stromal cell-derived factor 2-like 1
chr9_+_131902283 0.26 ENST00000436883.1
ENST00000414510.1
protein phosphatase 2A activator, regulatory subunit 4
chr10_+_104221137 0.26 ENST00000366277.2
ENST00000238936.4
ENST00000369931.3
transmembrane protein 180
chr15_+_80215113 0.26 ENST00000560255.1
chromosome 15 open reading frame 37
chr12_-_49463753 0.26 ENST00000301068.6
Ras homolog enriched in brain like 1
chr8_+_22436635 0.26 ENST00000452226.1
ENST00000397760.4
ENST00000339162.7
ENST00000397761.2
PDZ and LIM domain 2 (mystique)
chr11_-_67141640 0.26 ENST00000533438.1
cardiotrophin-like cytokine factor 1
chr14_+_77244349 0.26 ENST00000554743.1
vasohibin 1
chr2_+_239335636 0.25 ENST00000409297.1
ankyrin repeat and SOCS box containing 1
chr6_-_34524093 0.25 ENST00000544425.1
SAM pointed domain containing ETS transcription factor
chr19_-_47291843 0.25 ENST00000542575.2
solute carrier family 1 (neutral amino acid transporter), member 5
chr8_+_144640477 0.25 ENST00000262580.4
gasdermin D
chr8_+_22436248 0.25 ENST00000308354.7
PDZ and LIM domain 2 (mystique)
chr22_+_42665742 0.24 ENST00000332965.3
ENST00000415205.1
ENST00000446578.1
Z83851.3
chr12_+_47610315 0.23 ENST00000548348.1
ENST00000549500.1
PC-esterase domain containing 1B
chr14_-_23822080 0.23 ENST00000397267.1
ENST00000354772.3
solute carrier family 22, member 17
chr17_-_73839792 0.23 ENST00000590762.1
unc-13 homolog D (C. elegans)
chr19_+_3539152 0.23 ENST00000329493.5
chromosome 19 open reading frame 71
chr8_-_146078376 0.23 ENST00000533270.1
ENST00000305103.3
ENST00000402718.3
COMM domain containing 5
chr5_-_180230830 0.23 ENST00000427865.2
ENST00000514283.1
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr15_-_74494779 0.23 ENST00000571341.1
stimulated by retinoic acid 6
chr16_+_2570340 0.22 ENST00000568263.1
ENST00000293971.6
ENST00000302956.4
ENST00000413459.3
ENST00000566706.1
ENST00000569879.1
amidohydrolase domain containing 2
chr19_+_859654 0.22 ENST00000592860.1
complement factor D (adipsin)
chr10_-_375422 0.22 ENST00000434695.2
DIP2 disco-interacting protein 2 homolog C (Drosophila)
chr12_-_58027002 0.22 ENST00000449184.3
beta-1,4-N-acetyl-galactosaminyl transferase 1
chr5_+_175298487 0.22 ENST00000393745.3
complexin 2
chr19_+_11466062 0.21 ENST00000251473.5
ENST00000591329.1
ENST00000586380.1
Lipid phosphate phosphatase-related protein type 2
chr1_+_27113963 0.21 ENST00000430292.1
phosphatidylinositol glycan anchor biosynthesis, class V
chr22_-_30642782 0.21 ENST00000249075.3
leukemia inhibitory factor
chr1_+_200863949 0.21 ENST00000413687.2
chromosome 1 open reading frame 106
chr2_+_136499287 0.21 ENST00000415164.1
UBX domain protein 4
chr11_-_65548265 0.21 ENST00000532090.2
adaptor-related protein complex 5, beta 1 subunit
chr19_+_17413663 0.21 ENST00000594999.1
mitochondrial ribosomal protein L34
chr1_+_109642799 0.21 ENST00000602755.1
small Cajal body-specific RNA 2
chr6_+_30029008 0.21 ENST00000332435.5
ENST00000376782.2
ENST00000359374.4
ENST00000376785.2
zinc ribbon domain containing 1
chr1_+_11333546 0.20 ENST00000376804.2
UbiA prenyltransferase domain containing 1
chr2_-_11272234 0.20 ENST00000590207.1
ENST00000417697.2
ENST00000396164.1
ENST00000536743.1
ENST00000544306.1
AC062028.1
chr15_-_60695071 0.20 ENST00000557904.1
annexin A2
chr11_-_66104237 0.20 ENST00000530056.1
Ras and Rab interactor 1
chr20_+_43992094 0.20 ENST00000453003.1
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
chr9_-_35079911 0.20 ENST00000448890.1
Fanconi anemia, complementation group G
chrX_-_153707246 0.20 ENST00000407062.1
L antigen family, member 3
chr1_+_221051699 0.20 ENST00000366903.6
H2.0-like homeobox
chr22_-_42342692 0.20 ENST00000404067.1
ENST00000402338.1
centromere protein M
chrX_+_153238220 0.19 ENST00000425274.1
transmembrane protein 187
chr14_-_23791484 0.19 ENST00000594872.1
Uncharacterized protein
chr7_+_150076406 0.19 ENST00000329630.5
zinc finger protein 775
chr14_-_105767598 0.19 ENST00000548421.1
BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
chr14_-_23822061 0.19 ENST00000397260.3
solute carrier family 22, member 17
chr2_+_74685413 0.19 ENST00000233615.2
WW domain binding protein 1
chr6_-_34524049 0.19 ENST00000374037.3
SAM pointed domain containing ETS transcription factor
chr20_+_43343886 0.19 ENST00000190983.4
WNT1 inducible signaling pathway protein 2
chr11_+_6411670 0.19 ENST00000530395.1
ENST00000527275.1
sphingomyelin phosphodiesterase 1, acid lysosomal
chrX_+_119005399 0.18 ENST00000371437.4
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa
chr11_-_62323702 0.18 ENST00000530285.1
AHNAK nucleoprotein
chr11_-_796197 0.18 ENST00000530360.1
ENST00000528606.1
ENST00000320230.5
solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chrX_-_153707545 0.18 ENST00000357360.4
L antigen family, member 3
chrX_-_30327495 0.18 ENST00000453287.1
nuclear receptor subfamily 0, group B, member 1
chr17_+_1633755 0.18 ENST00000545662.1
WD repeat domain 81
chr1_-_157014865 0.18 ENST00000361409.2
Rho guanine nucleotide exchange factor (GEF) 11
chr1_+_9299895 0.18 ENST00000602477.1
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr19_+_54496132 0.18 ENST00000346968.2
calcium channel, voltage-dependent, gamma subunit 6
chr19_+_56989485 0.18 ENST00000585445.1
ENST00000586091.1
ENST00000594783.1
ENST00000592146.1
ENST00000588158.1
ENST00000299997.4
ENST00000591797.1
ZNF667 antisense RNA 1 (head to head)
chr15_-_55611306 0.18 ENST00000563262.1
RAB27A, member RAS oncogene family
chr3_-_195603566 0.18 ENST00000424563.1
ENST00000411741.1
tyrosine kinase, non-receptor, 2
chr11_-_117698765 0.18 ENST00000532119.1
FXYD domain containing ion transport regulator 2
chr22_-_42343117 0.17 ENST00000407253.3
ENST00000215980.5
centromere protein M
chr6_+_151358048 0.17 ENST00000450635.1
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr17_-_43025005 0.17 ENST00000587309.1
ENST00000593135.1
ENST00000339151.4
kinesin family member 18B
chr5_+_111496554 0.17 ENST00000442823.2
EPB41L4A antisense RNA 1
chrX_-_47509994 0.17 ENST00000343894.4
ELK1, member of ETS oncogene family
chr19_-_51014460 0.17 ENST00000595669.1
Josephin domain containing 2
chr15_+_73976715 0.17 ENST00000558689.1
ENST00000560786.2
ENST00000561213.1
ENST00000563584.1
ENST00000561416.1
CD276 molecule
chr22_+_31031639 0.17 ENST00000343605.4
ENST00000300385.8
solute carrier family 35, member E4
chr16_+_89979826 0.17 ENST00000555427.1
melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
chr19_-_41256207 0.17 ENST00000598485.2
ENST00000470681.1
ENST00000339153.3
ENST00000598729.1
chromosome 19 open reading frame 54
chr11_+_65337901 0.17 ENST00000309328.3
ENST00000531405.1
ENST00000527920.1
ENST00000526877.1
ENST00000533115.1
ENST00000526433.1
Sjogren syndrome/scleroderma autoantigen 1
chr17_+_46185111 0.17 ENST00000582104.1
ENST00000584335.1
sorting nexin 11
chr17_+_19281034 0.17 ENST00000308406.5
ENST00000299612.7
mitogen-activated protein kinase 7
chr11_-_66103932 0.17 ENST00000311320.4
Ras and Rab interactor 1
chr19_-_51014345 0.17 ENST00000391815.3
ENST00000594350.1
ENST00000601423.1
Josephin domain containing 2
chr9_+_131902346 0.17 ENST00000432124.1
ENST00000435305.1
protein phosphatase 2A activator, regulatory subunit 4
chr19_+_55996316 0.17 ENST00000205194.4
N-acetyltransferase 14 (GCN5-related, putative)
chr17_+_7358889 0.17 ENST00000575379.1
cholinergic receptor, nicotinic, beta 1 (muscle)
chr20_-_33460621 0.17 ENST00000427420.1
ENST00000336431.5
gamma-glutamyltransferase 7
chr7_+_150756657 0.16 ENST00000413384.2
solute carrier family 4 (anion exchanger), member 2
chr11_+_6411636 0.16 ENST00000299397.3
ENST00000356761.2
ENST00000342245.4
sphingomyelin phosphodiesterase 1, acid lysosomal
chr19_-_46296011 0.16 ENST00000377735.3
ENST00000270223.6
dystrophia myotonica, WD repeat containing
chr16_+_58033450 0.16 ENST00000561743.1
U6 snRNA biogenesis 1
chr9_+_139846708 0.16 ENST00000371633.3
lipocalin 12
chr1_+_201979743 0.16 ENST00000446188.1
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr3_-_134093738 0.16 ENST00000506107.1
angiomotin like 2
chr16_-_28621353 0.16 ENST00000567512.1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr1_-_235098861 0.16 ENST00000458044.1
RP11-443B7.1
chr17_-_56494882 0.16 ENST00000584437.1
ring finger protein 43
chr12_+_57916584 0.16 ENST00000546632.1
ENST00000549623.1
ENST00000431731.2
methyl-CpG binding domain protein 6
chr20_-_36794902 0.16 ENST00000373403.3
transglutaminase 2
chr20_+_43343476 0.15 ENST00000372868.2
WNT1 inducible signaling pathway protein 2
chr20_-_36794938 0.15 ENST00000453095.1
transglutaminase 2
chr7_+_99954224 0.15 ENST00000608825.1
paired immunoglobin-like type 2 receptor beta
chr7_+_76054224 0.15 ENST00000394857.3
zona pellucida glycoprotein 3 (sperm receptor)
chr8_+_35649365 0.15 ENST00000437887.1
Uncharacterized protein
chr9_-_131486367 0.15 ENST00000372663.4
ENST00000406904.2
ENST00000452105.1
ENST00000372672.2
ENST00000372667.5
zinc finger, DHHC-type containing 12
chr19_+_50015870 0.15 ENST00000599701.1
Fc fragment of IgG, receptor, transporter, alpha
chr20_-_62199427 0.15 ENST00000427522.2
helicase with zinc finger 2, transcriptional coactivator
chr12_-_54778244 0.15 ENST00000549937.1
zinc finger protein 385A
chr11_-_67141090 0.15 ENST00000312438.7
cardiotrophin-like cytokine factor 1
chr17_-_7145106 0.15 ENST00000577035.1
GABA(A) receptor-associated protein
chr17_+_27895609 0.15 ENST00000581411.2
ENST00000301057.7
tumor protein p53 inducible protein 13
chr1_-_108743471 0.15 ENST00000569674.1
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
chr16_-_11692320 0.15 ENST00000571627.1
lipopolysaccharide-induced TNF factor
chr16_-_67190152 0.15 ENST00000486556.1
TNFRSF1A-associated via death domain
chr22_-_50913371 0.15 ENST00000348911.6
ENST00000380817.3
ENST00000390679.3
SET binding factor 1
chr11_-_66103867 0.15 ENST00000424433.2
Ras and Rab interactor 1
chrX_-_106960285 0.15 ENST00000503515.1
ENST00000372397.2
TSC22 domain family, member 3
chr17_+_42634844 0.14 ENST00000315323.3
frizzled family receptor 2
chr19_+_859425 0.14 ENST00000327726.6
complement factor D (adipsin)
chr16_-_28608364 0.14 ENST00000533150.1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr16_-_1821721 0.14 ENST00000219302.3
NME/NM23 nucleoside diphosphate kinase 3
chr17_-_56494908 0.14 ENST00000577716.1
ring finger protein 43
chr11_-_62359027 0.14 ENST00000494385.1
ENST00000308436.7
terminal uridylyl transferase 1, U6 snRNA-specific
chr19_-_58864848 0.14 ENST00000263100.3
alpha-1-B glycoprotein
chr16_+_2106134 0.14 ENST00000467949.1
tuberous sclerosis 2
chr5_+_149877440 0.14 ENST00000518299.1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr20_+_62716348 0.14 ENST00000349451.3
opiate receptor-like 1
chr22_+_25003568 0.14 ENST00000447416.1
gamma-glutamyltransferase 1
chr1_+_149858461 0.14 ENST00000331380.2
histone cluster 2, H2ac
chr15_+_91416092 0.14 ENST00000559353.1
furin (paired basic amino acid cleaving enzyme)
chr6_-_27841289 0.14 ENST00000355981.2
histone cluster 1, H4l
chr4_+_89300158 0.14 ENST00000502870.1
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr11_+_2923619 0.14 ENST00000380574.1
solute carrier family 22, member 18
chr16_-_2260834 0.14 ENST00000562360.1
ENST00000566018.1
BRICHOS domain containing 5
chr4_-_860950 0.14 ENST00000511980.1
ENST00000510799.1
cyclin G associated kinase
chr11_-_117698787 0.14 ENST00000260287.2
FXYD domain containing ion transport regulator 2
chr6_+_26440700 0.14 ENST00000494393.1
ENST00000482451.1
ENST00000244519.2
ENST00000339789.4
ENST00000471353.1
ENST00000361232.3
ENST00000487627.1
ENST00000496719.1
ENST00000490254.1
ENST00000487272.1
butyrophilin, subfamily 3, member A3
chr15_+_41057818 0.14 ENST00000558467.1
GTP cyclohydrolase I feedback regulator
chr14_-_23284703 0.13 ENST00000555911.1
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr16_-_4817129 0.13 ENST00000545009.1
ENST00000219478.6
zinc finger protein 500
chr20_+_62492566 0.13 ENST00000369916.3
abhydrolase domain containing 16B
chr22_+_44427230 0.13 ENST00000444029.1
parvin, beta
chr5_+_175298573 0.13 ENST00000512824.1
complexin 2
chr2_+_74685527 0.13 ENST00000393972.3
ENST00000409737.1
ENST00000428943.1
WW domain binding protein 1
chr16_+_765092 0.13 ENST00000568223.2
meteorin, glial cell differentiation regulator
chr14_-_23285069 0.13 ENST00000554758.1
ENST00000397528.4
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr11_-_62358972 0.13 ENST00000278279.3
terminal uridylyl transferase 1, U6 snRNA-specific
chr11_+_62379194 0.13 ENST00000525801.1
ENST00000534093.1
retinal outer segment membrane protein 1
chr7_-_84569561 0.13 ENST00000439105.1
AC074183.4
chr16_+_4743688 0.13 ENST00000304301.6
ENST00000586252.1
nudix (nucleoside diphosphate linked moiety X)-type motif 16-like 1
chr19_-_56048456 0.13 ENST00000413299.1
SH3 domain binding kinase family, member 2
chr19_+_11466167 0.13 ENST00000591608.1
Lipid phosphate phosphatase-related protein type 2
chr1_+_149871171 0.13 ENST00000369150.1
bolA family member 1
chr19_+_41882598 0.13 ENST00000447302.2
ENST00000544232.1
ENST00000542945.1
ENST00000540732.1
transmembrane protein 91
2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial; Uncharacterized protein
chr9_+_137000484 0.13 ENST00000608937.1
ENST00000608739.1
WD repeat domain 5
chr6_+_143447322 0.13 ENST00000458219.1
androgen-induced 1
chr11_-_45940343 0.13 ENST00000532681.1
peroxisomal biogenesis factor 16
chr7_+_154720173 0.13 ENST00000397551.2
PAXIP1 antisense RNA 2
chr3_+_51575596 0.13 ENST00000409535.2
RAD54-like 2 (S. cerevisiae)
chr16_+_28875268 0.13 ENST00000395532.4
SH2B adaptor protein 1
chr2_+_239335449 0.13 ENST00000264607.4
ankyrin repeat and SOCS box containing 1
chr3_+_49941420 0.13 ENST00000419183.1
Uncharacterized protein
chr22_-_24989014 0.13 ENST00000318753.8
family with sequence similarity 211, member B
chr19_-_8408139 0.13 ENST00000330915.3
ENST00000593649.1
ENST00000595639.1
KN motif and ankyrin repeat domains 3
chr11_-_62379752 0.13 ENST00000466671.1
ENST00000466886.1
echinoderm microtubule associated protein like 3
chr3_-_119182453 0.13 ENST00000491685.1
ENST00000461654.1
transmembrane protein 39A
chr11_+_34999328 0.13 ENST00000526309.1
pyruvate dehydrogenase complex, component X
chr1_-_25291475 0.12 ENST00000338888.3
ENST00000399916.1
runt-related transcription factor 3
chr16_-_58033762 0.12 ENST00000299237.2
zinc finger protein 319
chr3_+_15643245 0.12 ENST00000303498.5
ENST00000437172.1
biotinidase
chr2_-_27531313 0.12 ENST00000296099.2
urocortin
chr6_-_31697977 0.12 ENST00000375787.2
dimethylarginine dimethylaminohydrolase 2
chr17_+_75396637 0.12 ENST00000590825.1
septin 9
chr11_+_45825616 0.12 ENST00000442528.2
ENST00000456334.1
ENST00000526817.1
solute carrier family 35 (GDP-fucose transporter), member C1
chr11_+_86502085 0.12 ENST00000527521.1
protease, serine, 23

Network of associatons between targets according to the STRING database.

First level regulatory network of RUNX1_RUNX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0070376 regulation of ERK5 cascade(GO:0070376) negative regulation of ERK5 cascade(GO:0070377)
0.1 0.8 GO:0046618 drug export(GO:0046618)
0.1 0.6 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.1 0.4 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.1 0.1 GO:0006109 regulation of carbohydrate metabolic process(GO:0006109)
0.1 0.4 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 0.8 GO:0030259 lipid glycosylation(GO:0030259)
0.1 0.3 GO:1903899 positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.1 0.3 GO:0002432 granuloma formation(GO:0002432)
0.1 0.5 GO:0060480 lung goblet cell differentiation(GO:0060480) lobar bronchus epithelium development(GO:0060481)
0.1 0.3 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.1 0.3 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.1 0.2 GO:0010585 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.1 0.3 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.1 0.3 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.1 0.2 GO:2000354 regulation of ovarian follicle development(GO:2000354)
0.1 0.5 GO:0048295 positive regulation of isotype switching to IgE isotypes(GO:0048295)
0.1 0.2 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.1 0.4 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.1 0.2 GO:1904636 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.1 0.2 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.1 0.2 GO:0052360 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.0 0.1 GO:0001922 B-1 B cell homeostasis(GO:0001922)
0.0 0.1 GO:0032904 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.0 0.2 GO:0019046 release from viral latency(GO:0019046)
0.0 0.3 GO:1902164 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.0 0.1 GO:0043105 regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.0 0.4 GO:0023021 termination of signal transduction(GO:0023021)
0.0 0.3 GO:0015878 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887)
0.0 0.2 GO:1905224 clathrin-coated pit assembly(GO:1905224)
0.0 0.1 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
0.0 0.2 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.2 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.0 0.1 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.0 0.3 GO:0070269 pyroptosis(GO:0070269)
0.0 0.7 GO:1901748 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 0.2 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.0 0.2 GO:2000538 regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.0 0.1 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.0 0.2 GO:0061143 alveolar primary septum development(GO:0061143)
0.0 0.8 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.6 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.4 GO:0000821 regulation of arginine metabolic process(GO:0000821) basic amino acid transmembrane transport(GO:1990822)
0.0 0.1 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.2 GO:0009233 menaquinone metabolic process(GO:0009233)
0.0 0.2 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.0 0.1 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.0 0.1 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.0 0.2 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.1 GO:0060380 regulation of single-stranded telomeric DNA binding(GO:0060380) positive regulation of single-stranded telomeric DNA binding(GO:0060381)
0.0 0.1 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
0.0 0.1 GO:1904597 regulation of connective tissue replacement involved in inflammatory response wound healing(GO:1904596) negative regulation of connective tissue replacement involved in inflammatory response wound healing(GO:1904597) regulation of advanced glycation end-product receptor activity(GO:1904603) negative regulation of advanced glycation end-product receptor activity(GO:1904604) negative regulation of connective tissue replacement(GO:1905204)
0.0 0.2 GO:2001033 negative regulation of double-strand break repair via nonhomologous end joining(GO:2001033)
0.0 0.1 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.6 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.1 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.0 0.1 GO:0046210 nitrate catabolic process(GO:0043602) nitric oxide catabolic process(GO:0046210)
0.0 0.5 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.1 GO:0098502 DNA dephosphorylation(GO:0098502)
0.0 0.3 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.2 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.2 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.0 0.2 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.1 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.2 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.1 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.0 0.1 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.0 0.1 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.0 0.1 GO:0051541 elastin metabolic process(GO:0051541)
0.0 0.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.1 GO:0036309 protein localization to M-band(GO:0036309)
0.0 0.2 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.1 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
0.0 0.1 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.0 0.1 GO:0072287 metanephric distal tubule morphogenesis(GO:0072287)
0.0 0.1 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.2 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 0.1 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.0 0.1 GO:1904845 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.0 0.1 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.1 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.0 0.1 GO:0050904 diapedesis(GO:0050904)
0.0 0.3 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.1 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.2 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.5 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.1 GO:0061760 antifungal humoral response(GO:0019732) antifungal innate immune response(GO:0061760)
0.0 0.0 GO:0008211 glucocorticoid metabolic process(GO:0008211)
0.0 0.1 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.0 0.1 GO:0002879 positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.0 0.1 GO:0048073 regulation of eye pigmentation(GO:0048073)
0.0 0.0 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.0 0.0 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621)
0.0 0.1 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.1 GO:0061083 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084) negative regulation of protein folding(GO:1903333)
0.0 0.1 GO:0070235 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.2 GO:0009304 tRNA transcription(GO:0009304)
0.0 0.2 GO:0035897 proteolysis in other organism(GO:0035897)
0.0 0.1 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.2 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.3 GO:0006068 ethanol catabolic process(GO:0006068)
0.0 0.0 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 0.1 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.1 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.0 0.2 GO:0032494 response to peptidoglycan(GO:0032494)
0.0 0.0 GO:1904995 negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995)
0.0 0.1 GO:0019056 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.0 0.0 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.0 0.1 GO:0046075 dTTP metabolic process(GO:0046075)
0.0 0.5 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.3 GO:0006768 biotin metabolic process(GO:0006768)
0.0 0.4 GO:0016180 snRNA processing(GO:0016180)
0.0 0.1 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.2 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
0.0 0.2 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.0 0.0 GO:0034136 negative regulation of toll-like receptor 2 signaling pathway(GO:0034136)
0.0 0.1 GO:0003095 pressure natriuresis(GO:0003095) vitamin E metabolic process(GO:0042360)
0.0 0.1 GO:0003150 muscular septum morphogenesis(GO:0003150)
0.0 0.0 GO:0072249 metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
0.0 0.2 GO:0033327 Leydig cell differentiation(GO:0033327)
0.0 0.4 GO:0030539 male genitalia development(GO:0030539)
0.0 0.2 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 0.3 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.1 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.1 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.0 GO:0010979 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0 0.0 GO:0060796 regulation of transcription involved in primary germ layer cell fate commitment(GO:0060796)
0.0 0.0 GO:0072387 flavin adenine dinucleotide metabolic process(GO:0072387)
0.0 0.1 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788) UDP-N-acetylglucosamine transmembrane transport(GO:1990569)
0.0 0.1 GO:1904245 regulation of polynucleotide adenylyltransferase activity(GO:1904245)
0.0 0.0 GO:0002589 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590)
0.0 0.2 GO:0015866 ADP transport(GO:0015866)
0.0 0.1 GO:0000432 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
0.0 0.0 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0 0.1 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.0 0.1 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 0.0 GO:0007341 penetration of zona pellucida(GO:0007341)
0.0 0.1 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.1 GO:0036512 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.0 0.1 GO:0051414 response to cortisol(GO:0051414)
0.0 0.1 GO:0036496 regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496)
0.0 0.1 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.0 0.1 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.1 GO:1904781 positive regulation of protein localization to centrosome(GO:1904781)
0.0 0.0 GO:0036414 citrulline metabolic process(GO:0000052) protein citrullination(GO:0018101) citrulline biosynthetic process(GO:0019240) histone citrullination(GO:0036414)
0.0 0.0 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 0.1 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.0 0.1 GO:0043129 surfactant homeostasis(GO:0043129)
0.0 0.0 GO:0051125 regulation of actin nucleation(GO:0051125)
0.0 0.0 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.0 0.1 GO:0030035 microspike assembly(GO:0030035)
0.0 0.0 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.0 0.2 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.1 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.1 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.1 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0 0.0 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.0 0.0 GO:0034721 histone H3-K4 demethylation, trimethyl-H3-K4-specific(GO:0034721)
0.0 0.1 GO:0032796 uropod organization(GO:0032796)
0.0 0.1 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.1 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.1 GO:1902527 positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255) positive regulation of protein monoubiquitination(GO:1902527)
0.0 0.0 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0070557 PCNA-p21 complex(GO:0070557)
0.1 0.4 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.1 0.2 GO:0002081 outer acrosomal membrane(GO:0002081)
0.0 0.2 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.0 0.4 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.5 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 0.2 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.0 0.2 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.2 GO:0031501 mannosyltransferase complex(GO:0031501)
0.0 0.2 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.3 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.5 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.3 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.0 0.1 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 0.1 GO:0035101 FACT complex(GO:0035101)
0.0 0.6 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.4 GO:0042599 lamellar body(GO:0042599)
0.0 0.2 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.1 GO:0043196 varicosity(GO:0043196)
0.0 0.1 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.0 0.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.1 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 0.1 GO:0002133 polycystin complex(GO:0002133)
0.0 0.4 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.2 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.1 GO:0070701 mucus layer(GO:0070701)
0.0 0.1 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559) cytoplasmic side of late endosome membrane(GO:0098560)
0.0 0.5 GO:0031105 septin complex(GO:0031105)
0.0 0.1 GO:0031905 early endosome lumen(GO:0031905)
0.0 0.0 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
0.0 0.0 GO:0044393 microspike(GO:0044393)
0.0 0.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.5 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.0 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.0 0.1 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.0 0.8 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.1 GO:0036038 MKS complex(GO:0036038)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.1 0.6 GO:0003947 (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity(GO:0003947)
0.1 0.3 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.1 0.3 GO:0047708 biotinidase activity(GO:0047708)
0.1 0.2 GO:0004584 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity(GO:0004584)
0.1 0.2 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.1 0.2 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.1 0.3 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1 0.2 GO:0019862 IgA binding(GO:0019862)
0.1 0.2 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.1 0.2 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0 0.2 GO:0001026 TFIIIB-type transcription factor activity(GO:0001026)
0.0 0.3 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.1 GO:0044549 GTP cyclohydrolase binding(GO:0044549)
0.0 0.3 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.0 GO:0001190 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0 0.2 GO:0008453 alanine-glyoxylate transaminase activity(GO:0008453)
0.0 0.1 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.0 0.2 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.4 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.2 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.0 0.7 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.2 GO:0036080 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.0 0.2 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.1 GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113)
0.0 0.2 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.0 0.3 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.0 0.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.2 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.6 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.1 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.0 0.1 GO:1904599 advanced glycation end-product binding(GO:1904599)
0.0 0.2 GO:0019770 IgG receptor activity(GO:0019770)
0.0 0.2 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.0 0.2 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.0 0.1 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
0.0 0.1 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) DNA/RNA helicase activity(GO:0033677)
0.0 0.1 GO:0047726 iron-cytochrome-c reductase activity(GO:0047726)
0.0 0.1 GO:0098518 polynucleotide phosphatase activity(GO:0098518)
0.0 0.3 GO:1901612 cardiolipin binding(GO:1901612)
0.0 0.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.2 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.1 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
0.0 0.1 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.0 0.1 GO:0070984 SET domain binding(GO:0070984)
0.0 0.1 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.0 0.2 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.3 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.2 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.0 0.2 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.1 GO:0070513 death domain binding(GO:0070513)
0.0 0.1 GO:0042020 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.0 0.2 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.1 GO:0045569 TRAIL binding(GO:0045569)
0.0 0.1 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 0.2 GO:0032190 acrosin binding(GO:0032190)
0.0 0.4 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.1 GO:0047661 racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.0 0.1 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.1 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.4 GO:0051400 BH domain binding(GO:0051400)
0.0 0.0 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.0 0.1 GO:0043426 MRF binding(GO:0043426)
0.0 0.3 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.1 GO:0035651 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.1 GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462)
0.0 0.1 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.0 GO:0035539 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
0.0 0.1 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.1 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 0.2 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.1 GO:0070991 medium-chain-acyl-CoA dehydrogenase activity(GO:0070991)
0.0 0.1 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.0 0.1 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.0 0.4 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.0 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.0 0.5 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.0 GO:0042007 interleukin-18 binding(GO:0042007)
0.0 0.7 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.8 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.0 GO:0000384 first spliceosomal transesterification activity(GO:0000384)
0.0 0.2 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.1 GO:0004515 nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.0 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.0 0.2 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.1 GO:0005124 scavenger receptor binding(GO:0005124)
0.0 0.0 GO:0008112 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.0 0.1 GO:1990405 protein antigen binding(GO:1990405)
0.0 0.0 GO:0005011 macrophage colony-stimulating factor receptor activity(GO:0005011)
0.0 0.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.1 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.0 0.1 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 0.0 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.0 GO:0004961 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.0 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 0.1 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.0 0.6 GO:0050699 WW domain binding(GO:0050699)
0.0 0.1 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.4 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.1 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 0.2 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.9 ST GA13 PATHWAY G alpha 13 Pathway
0.0 0.3 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.4 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.4 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.2 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.6 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.7 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.1 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.3 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.3 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling