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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for SMAD4

Z-value: 2.64

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Transcription factors associated with SMAD4

Gene Symbol Gene ID Gene Info
ENSG00000141646.9 SMAD family member 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SMAD4hg19_v2_chr18_+_48556470_48556640-0.955.3e-02Click!

Activity profile of SMAD4 motif

Sorted Z-values of SMAD4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_507299 2.77 ENST00000359315.5
tubulin polyglutamylase complex subunit 1
chr1_-_32827682 1.96 ENST00000432622.1
family with sequence similarity 229, member A
chr22_+_30752606 1.80 ENST00000399824.2
ENST00000405659.1
ENST00000338306.3
coiled-coil domain containing 157
chr2_+_233734994 1.76 ENST00000331342.2
chromosome 2 open reading frame 82
chr19_-_47734448 1.56 ENST00000439096.2
BCL2 binding component 3
chr16_+_3070356 1.46 ENST00000341627.5
ENST00000575124.1
ENST00000575836.1
tumor necrosis factor receptor superfamily, member 12A
chr19_+_51152702 1.36 ENST00000425202.1
chromosome 19 open reading frame 81
chr12_-_49365501 1.36 ENST00000403957.1
ENST00000301061.4
wingless-type MMTV integration site family, member 10B
chr6_-_26189304 1.34 ENST00000340756.2
histone cluster 1, H4d
chr17_-_7297833 1.21 ENST00000571802.1
ENST00000576201.1
ENST00000573213.1
ENST00000324822.11
TMEM256-PLSCR3 readthrough (NMD candidate)
chr11_+_66624527 1.19 ENST00000393952.3
leucine rich repeat and fibronectin type III domain containing 4
chr11_-_67120974 1.18 ENST00000539074.1
ENST00000312419.3
polymerase (DNA-directed), delta 4, accessory subunit
chr1_+_180165672 1.17 ENST00000443059.1
quiescin Q6 sulfhydryl oxidase 1
chr19_-_56092187 1.16 ENST00000325421.4
ENST00000592239.1
zinc finger protein 579
chr7_-_150777874 1.16 ENST00000540185.1
Fas-activated serine/threonine kinase
chr16_+_29840929 1.14 ENST00000566252.1
major vault protein
chr2_-_228028829 1.13 ENST00000396625.3
ENST00000329662.7
collagen, type IV, alpha 4
chr19_-_58864848 1.13 ENST00000263100.3
alpha-1-B glycoprotein
chr6_+_27791862 1.13 ENST00000355057.1
histone cluster 1, H4j
chr10_+_104180580 1.12 ENST00000425536.1
F-box and leucine-rich repeat protein 15
chr3_-_120400960 1.07 ENST00000476082.2
homogentisate 1,2-dioxygenase
chr2_+_232575168 1.07 ENST00000440384.1
prothymosin, alpha
chr8_+_144679984 1.06 ENST00000504548.2
ENST00000321385.3
tigger transposable element derived 5
chr3_-_48632593 1.01 ENST00000454817.1
ENST00000328333.8
collagen, type VII, alpha 1
chr8_-_144623595 1.01 ENST00000262577.5
zinc finger CCCH-type containing 3
chr2_-_74730430 1.00 ENST00000460508.3
ladybird homeobox 2
chr12_+_58166726 0.99 ENST00000546504.1
Uncharacterized protein
chr1_-_44482979 0.97 ENST00000360584.2
ENST00000357730.2
ENST00000528803.1
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr19_+_46171464 0.96 ENST00000590918.1
ENST00000263281.3
ENST00000304207.8
gastric inhibitory polypeptide receptor
chr9_-_130700080 0.96 ENST00000373110.4
dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit
chr8_+_22409193 0.95 ENST00000240123.7
sorbin and SH3 domain containing 3
chrX_-_30327495 0.93 ENST00000453287.1
nuclear receptor subfamily 0, group B, member 1
chr11_+_64879317 0.92 ENST00000526809.1
ENST00000279263.7
ENST00000524986.1
ENST00000534371.1
ENST00000540748.1
ENST00000525385.1
ENST00000345348.5
ENST00000531321.1
ENST00000529414.1
ENST00000526085.1
ENST00000530750.1
transmembrane 7 superfamily member 2
chr17_-_61777459 0.92 ENST00000578993.1
ENST00000583211.1
ENST00000259006.3
LIM domain containing 2
chr19_+_11466062 0.90 ENST00000251473.5
ENST00000591329.1
ENST00000586380.1
Lipid phosphate phosphatase-related protein type 2
chr2_+_130939827 0.89 ENST00000409255.1
ENST00000455239.1
mitotic spindle organizing protein 2B
chr19_-_44031341 0.89 ENST00000600651.1
ethylmalonic encephalopathy 1
chr6_-_26027480 0.88 ENST00000377364.3
histone cluster 1, H4b
chr17_-_73874654 0.87 ENST00000254816.2
tripartite motif containing 47
chr8_+_82066514 0.87 ENST00000519412.1
ENST00000521953.1
RP11-1149M10.2
chr16_-_31076273 0.87 ENST00000426488.2
zinc finger protein 668
chr9_-_14322319 0.86 ENST00000606230.1
nuclear factor I/B
chr17_-_8027402 0.85 ENST00000541682.2
ENST00000317814.4
ENST00000577735.1
hes family bHLH transcription factor 7
chr6_-_107230334 0.85 ENST00000607090.1
RP1-60O19.1
chr22_-_37823468 0.84 ENST00000402918.2
extracellular leucine-rich repeat and fibronectin type III domain containing 2
chr1_-_151345159 0.84 ENST00000458566.1
ENST00000447402.3
ENST00000426705.2
ENST00000435071.1
ENST00000368868.5
selenium binding protein 1
chr19_-_47287990 0.83 ENST00000593713.1
ENST00000598022.1
ENST00000434726.2
solute carrier family 1 (neutral amino acid transporter), member 5
chr19_+_49127600 0.82 ENST00000601704.1
ENST00000593308.1
sphingosine kinase 2
chr16_-_68002456 0.82 ENST00000576616.1
ENST00000572037.1
ENST00000338335.3
ENST00000422611.2
ENST00000316341.3
solute carrier family 12 (potassium/chloride transporter), member 4
chr8_-_144890847 0.81 ENST00000531942.1
scribbled planar cell polarity protein
chr19_-_44031375 0.80 ENST00000292147.2
ethylmalonic encephalopathy 1
chr7_-_55620433 0.79 ENST00000418904.1
vesicular, overexpressed in cancer, prosurvival protein 1
chr6_-_43197189 0.78 ENST00000509253.1
ENST00000393987.2
ENST00000230431.6
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
chr14_-_23288930 0.77 ENST00000554517.1
ENST00000285850.7
ENST00000397529.2
ENST00000555702.1
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr3_+_50316458 0.77 ENST00000316436.3
leucine-rich single-pass membrane protein 2
chr16_-_31076332 0.77 ENST00000539836.3
ENST00000535577.1
ENST00000442862.2
zinc finger protein 668
chr11_+_66742742 0.75 ENST00000308963.4
chromosome 11 open reading frame 86
chr17_-_7297519 0.75 ENST00000576362.1
ENST00000571078.1
TMEM256-PLSCR3 readthrough (NMD candidate)
chr9_+_139247484 0.75 ENST00000429455.1
G-protein signaling modulator 1
chr19_-_51014588 0.74 ENST00000598418.1
Josephin domain containing 2
chr17_-_7307358 0.74 ENST00000576017.1
ENST00000302422.3
ENST00000535512.1
transmembrane protein 256
TMEM256-PLSCR3 readthrough (NMD candidate)
chr7_-_100881109 0.73 ENST00000308344.5
claudin 15
chr1_+_24117627 0.72 ENST00000400061.1
lysophospholipase II
chr20_-_36794902 0.72 ENST00000373403.3
transglutaminase 2
chr3_-_195619579 0.72 ENST00000428187.1
tyrosine kinase, non-receptor, 2
chr6_+_30850862 0.72 ENST00000504651.1
ENST00000512694.1
ENST00000515233.1
discoidin domain receptor tyrosine kinase 1
chr5_-_132166303 0.71 ENST00000440118.1
shroom family member 1
chr3_+_183967409 0.71 ENST00000324557.4
ENST00000402825.3
endothelin converting enzyme 2
chr2_+_30454390 0.70 ENST00000395323.3
ENST00000406087.1
ENST00000404397.1
limb bud and heart development
chr3_+_9958758 0.69 ENST00000383812.4
ENST00000438091.1
ENST00000295981.3
ENST00000436503.1
ENST00000403601.3
ENST00000416074.2
ENST00000455057.1
interleukin 17 receptor C
chr16_+_618837 0.69 ENST00000409439.2
phosphatidylinositol glycan anchor biosynthesis, class Q
chr4_+_926171 0.69 ENST00000507319.1
ENST00000264771.4
transmembrane protein 175
chr19_-_42463418 0.68 ENST00000600292.1
ENST00000601078.1
ENST00000601891.1
ENST00000222008.6
Rab acceptor 1 (prenylated)
chr17_-_7761256 0.68 ENST00000575208.1
LSM domain containing 1
chr2_-_27558270 0.68 ENST00000454704.1
general transcription factor IIIC, polypeptide 2, beta 110kDa
chr11_+_76493294 0.68 ENST00000533752.1
tsukushi, small leucine rich proteoglycan
chr11_-_72414256 0.67 ENST00000427971.2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr8_+_145726472 0.67 ENST00000528430.1
protein phosphatase 1, regulatory subunit 16A
chr8_+_22436635 0.66 ENST00000452226.1
ENST00000397760.4
ENST00000339162.7
ENST00000397761.2
PDZ and LIM domain 2 (mystique)
chr15_-_40633101 0.66 ENST00000559313.1
chromosome 15 open reading frame 52
chr19_+_49128209 0.66 ENST00000599748.1
ENST00000443164.1
ENST00000599029.1
sphingosine kinase 2
chr1_-_44497118 0.66 ENST00000537678.1
ENST00000466926.1
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr19_+_50094866 0.65 ENST00000418929.2
proline rich 12
chr22_-_50968419 0.65 ENST00000425169.1
ENST00000395680.1
ENST00000395681.1
ENST00000395678.3
ENST00000252029.3
thymidine phosphorylase
chr19_-_7553852 0.65 ENST00000593547.1
peroxisomal biogenesis factor 11 gamma
chr19_-_7553889 0.65 ENST00000221480.1
peroxisomal biogenesis factor 11 gamma
chr16_+_57662527 0.65 ENST00000563374.1
ENST00000568234.1
ENST00000565770.1
ENST00000564338.1
ENST00000566164.1
G protein-coupled receptor 56
chr11_-_44972418 0.64 ENST00000525680.1
ENST00000528290.1
ENST00000530035.1
tumor protein p53 inducible protein 11
chr17_+_73642486 0.64 ENST00000579469.1
small integral membrane protein 6
chr19_-_41222775 0.64 ENST00000324464.3
ENST00000450541.1
ENST00000594720.1
aarF domain containing kinase 4
chr19_-_40324767 0.64 ENST00000601972.1
ENST00000430012.2
ENST00000323039.5
ENST00000348817.3
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
chr22_-_51066521 0.64 ENST00000395621.3
ENST00000395619.3
ENST00000356098.5
ENST00000216124.5
ENST00000453344.2
ENST00000547307.1
ENST00000547805.1
arylsulfatase A
chr19_-_48894104 0.63 ENST00000597017.1
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
chr11_-_72414430 0.63 ENST00000452383.2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr7_-_150777949 0.63 ENST00000482571.1
Fas-activated serine/threonine kinase
chr6_+_30850697 0.63 ENST00000509639.1
ENST00000412274.2
ENST00000507901.1
ENST00000507046.1
ENST00000437124.2
ENST00000454612.2
ENST00000396342.2
discoidin domain receptor tyrosine kinase 1
chr4_-_13546632 0.63 ENST00000382438.5
NK3 homeobox 2
chr16_+_68279207 0.62 ENST00000413021.2
ENST00000565744.1
ENST00000219345.5
phospholipase A2, group XV
chr6_-_31612808 0.62 ENST00000438149.1
BCL2-associated athanogene 6
chr4_+_926214 0.62 ENST00000514453.1
ENST00000515492.1
ENST00000509508.1
ENST00000515740.1
ENST00000508204.1
ENST00000510493.1
ENST00000514546.1
transmembrane protein 175
chr22_+_45072925 0.61 ENST00000006251.7
proline rich 5 (renal)
chr20_-_1165117 0.61 ENST00000381894.3
transmembrane protein 74B
chr7_-_150777920 0.61 ENST00000353841.2
ENST00000297532.6
Fas-activated serine/threonine kinase
chr6_-_43484621 0.61 ENST00000506469.1
ENST00000503972.1
Yip1 domain family, member 3
chr17_-_40828969 0.61 ENST00000591022.1
ENST00000587627.1
ENST00000293349.6
pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr8_+_22424551 0.61 ENST00000523348.1
sorbin and SH3 domain containing 3
chr16_-_57798253 0.61 ENST00000565270.1
kinesin family member C3
chr15_-_83224682 0.60 ENST00000562833.1
RP11-152F13.10
chr1_+_1370903 0.60 ENST00000338660.5
ENST00000404702.3
ENST00000476993.1
ENST00000471398.1
von Willebrand factor A domain containing 1
chr8_-_29940569 0.60 ENST00000523761.1
transmembrane protein 66
chr6_-_26285737 0.59 ENST00000377727.1
ENST00000289352.1
histone cluster 1, H4h
chr19_+_11466167 0.59 ENST00000591608.1
Lipid phosphate phosphatase-related protein type 2
chr3_+_9958870 0.59 ENST00000413608.1
interleukin 17 receptor C
chr19_+_33685490 0.58 ENST00000253193.7
low density lipoprotein receptor-related protein 3
chr17_+_41476327 0.58 ENST00000320033.4
ADP-ribosylation factor-like 4D
chr14_-_23451845 0.58 ENST00000262713.2
ajuba LIM protein
chr5_-_180242534 0.58 ENST00000333055.3
ENST00000513431.1
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr17_+_17584763 0.58 ENST00000353383.1
retinoic acid induced 1
chr19_+_41092680 0.58 ENST00000594298.1
ENST00000597396.1
SH3KBP1 binding protein 1
chr11_+_64053890 0.58 ENST00000438980.2
ENST00000313074.3
ENST00000542190.1
ENST00000541952.1
G protein-coupled receptor 137
chr7_+_99699179 0.57 ENST00000438383.1
ENST00000429084.1
ENST00000359593.4
ENST00000439416.1
adaptor-related protein complex 4, mu 1 subunit
chr19_+_677885 0.57 ENST00000591552.2
follistatin-like 3 (secreted glycoprotein)
chr19_+_49617581 0.57 ENST00000391864.3
lin-7 homolog B (C. elegans)
chr11_-_65150103 0.57 ENST00000294187.6
ENST00000398802.1
ENST00000360662.3
ENST00000377152.2
ENST00000530936.1
solute carrier family 25, member 45
chr11_-_798305 0.57 ENST00000531514.1
solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chr20_-_36794938 0.57 ENST00000453095.1
transglutaminase 2
chr12_-_54778244 0.57 ENST00000549937.1
zinc finger protein 385A
chr15_+_75335604 0.56 ENST00000563393.1
phosphopantothenoylcysteine decarboxylase
chr7_+_7222157 0.56 ENST00000419721.1
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
chr19_+_48898132 0.56 ENST00000263269.3
glutamate receptor, ionotropic, N-methyl D-aspartate 2D
chr3_+_126243126 0.56 ENST00000319340.2
carbohydrate (chondroitin 4) sulfotransferase 13
chr1_+_110162448 0.56 ENST00000342115.4
ENST00000469039.2
ENST00000474459.1
ENST00000528667.1
adenosine monophosphate deaminase 2
chr19_-_10227503 0.56 ENST00000593054.1
eukaryotic translation initiation factor 3, subunit G
chr22_+_45072958 0.55 ENST00000403581.1
proline rich 5 (renal)
chr2_+_217524323 0.55 ENST00000456764.1
insulin-like growth factor binding protein 2, 36kDa
chr2_-_219151984 0.55 ENST00000444000.1
ENST00000418569.1
transmembrane BAX inhibitor motif containing 1
chr8_-_144886321 0.54 ENST00000526832.1
scribbled planar cell polarity protein
chr7_+_100081542 0.54 ENST00000300179.2
ENST00000423930.1
neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 1
chr19_-_2042065 0.54 ENST00000591588.1
ENST00000591142.1
MAP kinase interacting serine/threonine kinase 2
chr17_-_40829026 0.54 ENST00000412503.1
pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr8_-_48651648 0.53 ENST00000408965.3
CCAAT/enhancer binding protein (C/EBP), delta
chr19_+_41305740 0.53 ENST00000596517.1
egl-9 family hypoxia-inducible factor 2
chr14_-_23451467 0.53 ENST00000555074.1
ENST00000361265.4
RP11-298I3.5
ajuba LIM protein
chr10_-_93669233 0.53 ENST00000311575.5
fibroblast growth factor binding protein 3
chr14_+_102276192 0.53 ENST00000557714.1
protein phosphatase 2, regulatory subunit B', gamma
chr8_+_22436248 0.52 ENST00000308354.7
PDZ and LIM domain 2 (mystique)
chr19_+_49661079 0.52 ENST00000355712.5
transient receptor potential cation channel, subfamily M, member 4
chr19_-_49015050 0.52 ENST00000600059.1
lemur tyrosine kinase 3
chr19_+_40873617 0.52 ENST00000599353.1
phospholipase D family, member 3
chr7_+_99699280 0.52 ENST00000421755.1
adaptor-related protein complex 4, mu 1 subunit
chr16_+_616995 0.52 ENST00000293874.2
ENST00000409527.2
ENST00000424439.2
ENST00000540585.1
phosphatidylinositol glycan anchor biosynthesis, class Q
NHL repeat containing 4
chr22_-_27620603 0.51 ENST00000418271.1
ENST00000444114.1
RP5-1172A22.1
chr17_+_18163848 0.51 ENST00000323019.4
ENST00000578174.1
ENST00000395704.4
ENST00000395703.4
ENST00000578621.1
ENST00000579341.1
mitochondrial elongation factor 2
chr6_-_32908792 0.51 ENST00000418107.2
major histocompatibility complex, class II, DM beta
chr16_+_58059470 0.51 ENST00000219271.3
matrix metallopeptidase 15 (membrane-inserted)
chr19_-_55881741 0.51 ENST00000264563.2
ENST00000590625.1
ENST00000585513.1
interleukin 11
chr22_+_40573921 0.51 ENST00000454349.2
ENST00000335727.9
trinucleotide repeat containing 6B
chr2_-_227664474 0.50 ENST00000305123.5
insulin receptor substrate 1
chr5_-_132166579 0.50 ENST00000378679.3
shroom family member 1
chr16_+_31483374 0.50 ENST00000394863.3
transforming growth factor beta 1 induced transcript 1
chr5_-_180242576 0.49 ENST00000514438.1
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr1_-_27930102 0.49 ENST00000247087.5
ENST00000374011.2
AT hook, DNA binding motif, containing 1
chr16_+_532503 0.49 ENST00000412256.1
RAB11 family interacting protein 3 (class II)
chr19_-_51017881 0.49 ENST00000601207.1
ENST00000598657.1
ENST00000376916.3
aspartate dehydrogenase domain containing
chr2_-_112237835 0.49 ENST00000442293.1
ENST00000439494.1
MIR4435-1 host gene (non-protein coding)
chr6_+_24357131 0.49 ENST00000274766.1
kidney associated antigen 1
chr14_-_23822061 0.49 ENST00000397260.3
solute carrier family 22, member 17
chr11_+_63998006 0.48 ENST00000355040.4
DnaJ (Hsp40) homolog, subfamily C, member 4
chr16_-_30905584 0.48 ENST00000380317.4
B-cell CLL/lymphoma 7C
chr19_-_59031118 0.48 ENST00000600990.1
zinc finger and BTB domain containing 45
chr19_+_49838653 0.48 ENST00000598095.1
ENST00000426897.2
ENST00000323906.4
ENST00000535669.2
ENST00000597602.1
ENST00000595660.1
CD37 molecule
chr19_+_56653064 0.48 ENST00000593100.1
zinc finger protein 444
chr19_-_59030921 0.48 ENST00000354590.3
ENST00000596739.1
zinc finger and BTB domain containing 45
chr1_+_1334895 0.47 ENST00000448629.2
ENST00000444362.1
HCG20425, isoform CRA_a; Uncharacterized protein; cDNA FLJ53815
chr16_+_70695570 0.47 ENST00000597002.1
FLJ00418
chr1_-_204654826 0.47 ENST00000367177.3
leucine rich repeat neuronal 2
chr22_-_20731541 0.47 ENST00000292729.8
ubiquitin specific peptidase 41
chr11_+_67777751 0.47 ENST00000316367.6
ENST00000007633.8
ENST00000342456.6
aldehyde dehydrogenase 3 family, member B1
chr3_+_9834227 0.47 ENST00000287613.7
ENST00000397261.3
actin related protein 2/3 complex, subunit 4, 20kDa
chr11_-_568369 0.47 ENST00000534540.1
ENST00000528245.1
ENST00000500447.1
ENST00000533920.1
MIR210 host gene (non-protein coding)
chr19_-_47288162 0.47 ENST00000594991.1
solute carrier family 1 (neutral amino acid transporter), member 5
chr1_+_223889310 0.47 ENST00000434648.1
calpain 2, (m/II) large subunit
chr17_+_36886478 0.47 ENST00000439660.2
CDGSH iron sulfur domain 3
chr19_+_52076425 0.47 ENST00000436511.2
zinc finger protein 175
chr14_-_23426322 0.46 ENST00000555367.1
HAUS augmin-like complex, subunit 4
chr3_-_47950745 0.46 ENST00000429422.1
microtubule-associated protein 4
chr5_+_149877440 0.46 ENST00000518299.1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr7_-_156803329 0.46 ENST00000252971.6
motor neuron and pancreas homeobox 1
chr22_+_50639408 0.46 ENST00000380903.2
Selenoprotein O
chr22_-_24322019 0.46 ENST00000350608.3
D-dopachrome tautomerase
chr19_+_50832943 0.46 ENST00000542413.1
nuclear receptor subfamily 1, group H, member 2
chr12_-_42631529 0.46 ENST00000548917.1
YY1 associated factor 2
chr19_+_56186606 0.46 ENST00000085079.7
epsin 1
chr19_+_3708338 0.46 ENST00000590545.1
tight junction protein 3
chr9_-_92051354 0.46 ENST00000418828.1
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
chr18_+_3449330 0.45 ENST00000549253.1
TGFB-induced factor homeobox 1
chr1_+_155178481 0.45 ENST00000368376.3
metaxin 1
chr17_+_77020224 0.45 ENST00000339142.2
C1q and tumor necrosis factor related protein 1
chr17_-_40288449 0.45 ENST00000552162.1
ENST00000550504.1
RAB5C, member RAS oncogene family
chr1_-_156390128 0.45 ENST00000368242.3
chromosome 1 open reading frame 61

Network of associatons between targets according to the STRING database.

First level regulatory network of SMAD4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.4 1.7 GO:1903803 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.4 1.5 GO:0006669 sphinganine-1-phosphate biosynthetic process(GO:0006669)
0.3 1.3 GO:0098968 neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
0.3 2.8 GO:0007288 sperm axoneme assembly(GO:0007288)
0.3 1.4 GO:0051885 positive regulation of anagen(GO:0051885)
0.3 1.7 GO:0070221 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.3 0.8 GO:0090108 positive regulation of high-density lipoprotein particle assembly(GO:0090108) positive regulation of pancreatic juice secretion(GO:0090187) positive regulation of secretion of lysosomal enzymes(GO:0090340)
0.3 1.6 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.3 1.3 GO:0018262 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.2 0.7 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.2 0.6 GO:0019364 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.2 0.8 GO:1905224 clathrin-coated pit assembly(GO:1905224)
0.2 1.3 GO:1902162 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.2 0.6 GO:2001190 MHC class II protein complex assembly(GO:0002399) peptide antigen assembly with MHC class II protein complex(GO:0002503) positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.2 1.1 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.2 0.7 GO:1904199 positive regulation of regulation of vascular smooth muscle cell membrane depolarization(GO:1904199) regulation of vascular smooth muscle cell membrane depolarization(GO:1990736)
0.2 0.5 GO:0045210 negative regulation of dendritic cell cytokine production(GO:0002731) FasL biosynthetic process(GO:0045210)
0.2 1.5 GO:0006572 tyrosine catabolic process(GO:0006572)
0.2 0.7 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.2 0.8 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.2 1.3 GO:0044375 regulation of peroxisome size(GO:0044375)
0.2 1.3 GO:0097396 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.2 0.5 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.2 0.6 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.2 1.2 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.2 2.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.1 1.5 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.1 0.4 GO:0072356 chromosome passenger complex localization to kinetochore(GO:0072356)
0.1 0.8 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.1 1.0 GO:0019348 dolichol metabolic process(GO:0019348)
0.1 1.0 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.1 0.5 GO:0048691 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.1 1.1 GO:0014807 regulation of somitogenesis(GO:0014807)
0.1 1.2 GO:1990822 basic amino acid transmembrane transport(GO:1990822)
0.1 1.1 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.1 0.8 GO:2000035 regulation of stem cell division(GO:2000035)
0.1 0.3 GO:0007506 gonadal mesoderm development(GO:0007506)
0.1 0.3 GO:2000354 regulation of ovarian follicle development(GO:2000354)
0.1 0.3 GO:0060620 regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.1 0.3 GO:0006624 vacuolar protein processing(GO:0006624)
0.1 0.5 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.1 0.6 GO:0042335 cuticle development(GO:0042335)
0.1 0.4 GO:0000103 sulfate assimilation(GO:0000103)
0.1 0.5 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.1 0.6 GO:2000504 negative regulation of Fas signaling pathway(GO:1902045) positive regulation of blood vessel remodeling(GO:2000504)
0.1 0.3 GO:0046521 sphingoid catabolic process(GO:0046521)
0.1 0.5 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.1 1.1 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.1 1.0 GO:0002084 protein depalmitoylation(GO:0002084)
0.1 0.7 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 0.3 GO:0001300 chronological cell aging(GO:0001300)
0.1 0.4 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.1 0.8 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.1 0.3 GO:0072081 proximal/distal pattern formation involved in nephron development(GO:0072047) specification of nephron tubule identity(GO:0072081)
0.1 0.5 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659)
0.1 0.3 GO:1905044 Schwann cell proliferation involved in axon regeneration(GO:0014011) negative regulation of Schwann cell migration(GO:1900148) regulation of Schwann cell proliferation involved in axon regeneration(GO:1905044) negative regulation of Schwann cell proliferation involved in axon regeneration(GO:1905045)
0.1 0.3 GO:0036451 cap mRNA methylation(GO:0036451)
0.1 0.8 GO:0015889 cobalamin transport(GO:0015889)
0.1 0.3 GO:0033122 negative regulation of cyclic nucleotide catabolic process(GO:0030806) negative regulation of cAMP catabolic process(GO:0030821) negative regulation of purine nucleotide catabolic process(GO:0033122)
0.1 0.6 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.1 0.2 GO:0006427 histidyl-tRNA aminoacylation(GO:0006427)
0.1 1.2 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.1 0.3 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.1 0.4 GO:0010693 negative regulation of alkaline phosphatase activity(GO:0010693)
0.1 0.5 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.4 GO:0070384 Harderian gland development(GO:0070384)
0.1 0.2 GO:0052509 induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528)
0.1 0.4 GO:0034227 tRNA thio-modification(GO:0034227)
0.1 1.2 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 0.2 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621)
0.1 0.3 GO:0060605 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.1 0.7 GO:0045218 zonula adherens maintenance(GO:0045218)
0.1 0.6 GO:0042791 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.1 0.4 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.1 0.6 GO:1904379 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.1 0.5 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1 0.9 GO:0030238 male sex determination(GO:0030238)
0.1 0.5 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.1 1.2 GO:0038203 TORC2 signaling(GO:0038203)
0.1 0.5 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.1 0.8 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.1 0.2 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.1 0.3 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 0.8 GO:0009125 nucleoside monophosphate catabolic process(GO:0009125)
0.1 0.2 GO:0002432 granuloma formation(GO:0002432)
0.1 0.8 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.1 0.5 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.1 0.3 GO:0046092 deoxycytidine metabolic process(GO:0046092)
0.1 1.0 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
0.1 0.3 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.1 0.5 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.1 0.6 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 0.3 GO:0070829 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.1 0.4 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.3 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.5 GO:0044351 macropinocytosis(GO:0044351)
0.0 0.3 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.0 0.1 GO:0090472 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.0 0.4 GO:0070235 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.6 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.5 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.8 GO:0008655 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0 0.1 GO:0000349 generation of catalytic spliceosome for first transesterification step(GO:0000349)
0.0 0.4 GO:0032264 IMP salvage(GO:0032264)
0.0 0.3 GO:0046087 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.0 0.4 GO:0023041 neuronal signal transduction(GO:0023041)
0.0 0.2 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.0 0.4 GO:0097240 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.5 GO:0006477 protein sulfation(GO:0006477)
0.0 0.3 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.0 0.4 GO:0015808 L-alanine transport(GO:0015808) proline transmembrane transport(GO:0035524)
0.0 0.2 GO:1903906 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.0 0.9 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.4 GO:0046541 saliva secretion(GO:0046541)
0.0 0.2 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.0 0.1 GO:0034085 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0 0.2 GO:2001300 lipoxin metabolic process(GO:2001300)
0.0 0.2 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.2 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.0 0.7 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.0 0.7 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.2 GO:0061143 alveolar primary septum development(GO:0061143)
0.0 0.4 GO:0071988 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.0 0.3 GO:0048549 positive regulation of pinocytosis(GO:0048549)
0.0 0.5 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.0 0.1 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.0 1.1 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.3 GO:0072143 mesangial cell development(GO:0072143) glomerular mesangial cell development(GO:0072144)
0.0 0.1 GO:0001837 epithelial to mesenchymal transition(GO:0001837)
0.0 0.2 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
0.0 0.6 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.5 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 1.1 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.4 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.1 GO:0042427 serotonin biosynthetic process(GO:0042427)
0.0 0.6 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.4 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.5 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.1 GO:0010615 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) positive regulation of connective tissue replacement(GO:1905205)
0.0 0.2 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 0.6 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0 0.4 GO:1902430 negative regulation of beta-amyloid formation(GO:1902430)
0.0 0.3 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.0 0.2 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 1.2 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 0.0 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
0.0 0.4 GO:0015813 L-glutamate transport(GO:0015813)
0.0 0.4 GO:1900825 regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900825)
0.0 0.8 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.1 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.2 GO:0051958 methotrexate transport(GO:0051958)
0.0 1.6 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 0.1 GO:0006601 creatine biosynthetic process(GO:0006601)
0.0 0.7 GO:0010002 cardioblast differentiation(GO:0010002)
0.0 0.2 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.0 0.2 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.0 0.7 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.1 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 0.3 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.1 GO:0019417 sulfur oxidation(GO:0019417)
0.0 0.3 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.0 0.5 GO:0046185 aldehyde catabolic process(GO:0046185)
0.0 0.4 GO:0070365 hepatocyte differentiation(GO:0070365)
0.0 0.1 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 0.2 GO:0016321 female meiosis chromosome segregation(GO:0016321)
0.0 0.1 GO:0060481 lung goblet cell differentiation(GO:0060480) lobar bronchus epithelium development(GO:0060481)
0.0 0.1 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.0 0.0 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.0 0.3 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 1.3 GO:0006266 DNA ligation(GO:0006266)
0.0 0.2 GO:0060019 radial glial cell differentiation(GO:0060019)
0.0 0.3 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.3 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.7 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.4 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.0 GO:0060681 branch elongation involved in ureteric bud branching(GO:0060681)
0.0 0.4 GO:0015684 ferrous iron transport(GO:0015684) ferrous iron transmembrane transport(GO:1903874)
0.0 0.1 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.2 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.5 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.1 GO:0061364 apoptotic process involved in luteolysis(GO:0061364)
0.0 0.2 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.0 0.5 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.1 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0 0.5 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.3 GO:0010990 regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.2 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.0 0.4 GO:0007566 embryo implantation(GO:0007566)
0.0 1.0 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.0 0.1 GO:0042631 cellular response to water deprivation(GO:0042631)
0.0 0.4 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.3 GO:1901678 iron coordination entity transport(GO:1901678)
0.0 0.2 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.0 0.2 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.3 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0 0.1 GO:0060827 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827) negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.0 0.7 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.2 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.5 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.1 GO:0007320 insemination(GO:0007320)
0.0 0.2 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.7 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 1.6 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.1 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.0 0.1 GO:0015862 uridine transport(GO:0015862)
0.0 0.2 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.4 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.7 GO:0051931 regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931)
0.0 0.8 GO:1901570 icosanoid biosynthetic process(GO:0046456) fatty acid derivative biosynthetic process(GO:1901570)
0.0 0.1 GO:0010976 positive regulation of neuron projection development(GO:0010976)
0.0 0.3 GO:1904903 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.0 0.1 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
0.0 0.1 GO:1903772 virus maturation(GO:0019075) regulation of viral budding via host ESCRT complex(GO:1903772)
0.0 0.2 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.2 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.1 GO:1902659 regulation of glucose mediated signaling pathway(GO:1902659)
0.0 0.1 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.0 0.2 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.1 GO:0010225 response to UV-C(GO:0010225)
0.0 0.1 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.4 GO:0060065 uterus development(GO:0060065)
0.0 0.2 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.6 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.3 GO:0072189 ureter development(GO:0072189)
0.0 0.1 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.3 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 1.2 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 0.2 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.0 0.2 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.0 GO:0006570 tyrosine metabolic process(GO:0006570)
0.0 0.0 GO:0046495 nicotinamide riboside catabolic process(GO:0006738) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638)
0.0 0.5 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742)
0.0 0.2 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.0 0.1 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.1 GO:1901376 mycotoxin metabolic process(GO:0043385) aflatoxin metabolic process(GO:0046222) organic heteropentacyclic compound metabolic process(GO:1901376)
0.0 0.1 GO:0060369 positive regulation of natural killer cell cytokine production(GO:0002729) positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.0 0.3 GO:0042303 molting cycle(GO:0042303) hair cycle(GO:0042633)
0.0 0.1 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.0 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.0 0.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.7 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.3 GO:0050995 negative regulation of lipid catabolic process(GO:0050995)
0.0 0.7 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.3 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.1 GO:1904139 mammary gland fat development(GO:0060611) mammary duct terminal end bud growth(GO:0060763) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139) positive regulation of microglial cell migration(GO:1904141)
0.0 0.3 GO:0043949 regulation of cAMP-mediated signaling(GO:0043949)
0.0 0.3 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.0 0.1 GO:0002934 desmosome organization(GO:0002934)
0.0 0.0 GO:0003180 aortic valve development(GO:0003176) aortic valve morphogenesis(GO:0003180) endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.0 0.2 GO:0019532 oxalate transport(GO:0019532)
0.0 0.2 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.1 GO:0043542 endothelial cell migration(GO:0043542)
0.0 0.4 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.2 GO:0006636 unsaturated fatty acid biosynthetic process(GO:0006636)
0.0 0.2 GO:0021756 striatum development(GO:0021756)
0.0 0.2 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.0 0.1 GO:0033489 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.0 0.1 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 0.2 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.0 0.1 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.0 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.0 0.1 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.0 0.5 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.4 GO:0042438 melanin biosynthetic process(GO:0042438)
0.0 0.1 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.0 0.2 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.0 GO:0010446 response to alkaline pH(GO:0010446)
0.0 0.1 GO:0006825 copper ion transport(GO:0006825)
0.0 0.1 GO:0070836 caveola assembly(GO:0070836)
0.0 0.0 GO:0060018 astrocyte fate commitment(GO:0060018)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.2 1.0 GO:0030934 anchoring collagen complex(GO:0030934)
0.2 1.2 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.2 1.3 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.1 1.1 GO:0005587 collagen type IV trimer(GO:0005587)
0.1 1.1 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 0.5 GO:0031523 Myb complex(GO:0031523)
0.1 0.7 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.1 0.7 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.1 1.3 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 1.1 GO:0061689 tricellular tight junction(GO:0061689)
0.1 0.3 GO:0072563 endothelial microparticle(GO:0072563)
0.1 0.3 GO:0071665 gamma-catenin-TCF7L2 complex(GO:0071665)
0.1 0.9 GO:0008274 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.1 0.2 GO:0071821 FANCM-MHF complex(GO:0071821)
0.1 1.1 GO:0070652 HAUS complex(GO:0070652)
0.1 0.9 GO:0042788 polysomal ribosome(GO:0042788)
0.1 0.7 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.6 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.1 0.4 GO:0005899 insulin receptor complex(GO:0005899)
0.1 0.5 GO:0070531 BRCA1-A complex(GO:0070531)
0.1 0.4 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.1 0.6 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1 0.4 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.8 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.8 GO:0005915 zonula adherens(GO:0005915)
0.0 0.5 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 1.2 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.2 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.2 GO:0031905 early endosome lumen(GO:0031905)
0.0 0.2 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
0.0 0.7 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 1.2 GO:0005581 collagen trimer(GO:0005581)
0.0 0.4 GO:0055028 cortical microtubule(GO:0055028)
0.0 0.1 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.1 GO:0031085 BLOC-3 complex(GO:0031085)
0.0 0.9 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.2 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 0.5 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.6 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.0 2.2 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.4 GO:0030478 actin cap(GO:0030478)
0.0 0.1 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.0 0.1 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.0 0.6 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.2 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.0 1.0 GO:0016460 myosin II complex(GO:0016460)
0.0 0.3 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.2 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0 0.2 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.3 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.1 GO:0020003 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
0.0 0.8 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.7 GO:0034706 sodium channel complex(GO:0034706)
0.0 0.2 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.6 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.2 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.2 GO:0043034 costamere(GO:0043034)
0.0 0.2 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.3 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.2 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.1 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.2 GO:0032010 phagolysosome(GO:0032010)
0.0 0.1 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.0 0.4 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.2 GO:0005883 neurofilament(GO:0005883)
0.0 0.2 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 2.8 GO:0031514 motile cilium(GO:0031514)
0.0 1.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.2 GO:0033643 host cell part(GO:0033643)
0.0 0.4 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.7 GO:0016592 mediator complex(GO:0016592)
0.0 0.1 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 1.7 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.3 GO:0031528 microvillus membrane(GO:0031528)
0.0 1.3 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.2 GO:0072546 ER membrane protein complex(GO:0072546)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.5 2.1 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.3 2.8 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.3 0.9 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.3 0.8 GO:0001133 RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding(GO:0001133)
0.3 1.8 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.2 1.0 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.2 1.2 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.2 0.9 GO:0033981 D-dopachrome decarboxylase activity(GO:0033981)
0.2 0.7 GO:0004522 ribonuclease A activity(GO:0004522)
0.2 1.7 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.2 0.6 GO:0003978 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.2 0.5 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.2 0.6 GO:0005046 KDEL sequence binding(GO:0005046)
0.1 0.4 GO:0005055 laminin receptor activity(GO:0005055)
0.1 0.4 GO:0045485 omega-6 fatty acid desaturase activity(GO:0045485)
0.1 0.4 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.1 0.4 GO:0038131 neuregulin receptor activity(GO:0038131)
0.1 1.3 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 0.4 GO:0015633 zinc transporting ATPase activity(GO:0015633)
0.1 1.1 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.1 1.3 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.1 1.6 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 1.4 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 1.3 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 0.3 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.1 0.4 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.1 2.5 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 0.3 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.1 0.6 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.1 0.3 GO:0042007 interleukin-18 binding(GO:0042007)
0.1 0.3 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.1 3.0 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 0.2 GO:0031177 phosphopantetheine binding(GO:0031177)
0.1 0.2 GO:0004821 histidine-tRNA ligase activity(GO:0004821)
0.1 0.4 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.1 0.8 GO:0031419 cobalamin binding(GO:0031419)
0.1 1.5 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.1 1.0 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.4 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 0.5 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.1 1.2 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 1.2 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.1 0.6 GO:0004969 histamine receptor activity(GO:0004969)
0.1 0.3 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.3 GO:0008453 alanine-glyoxylate transaminase activity(GO:0008453)
0.1 0.8 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 1.2 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.1 0.3 GO:0004796 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.1 0.1 GO:0004947 bradykinin receptor activity(GO:0004947)
0.1 0.9 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.1 0.4 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.1 0.3 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.1 0.8 GO:0097016 L27 domain binding(GO:0097016)
0.1 0.7 GO:0004645 phosphorylase activity(GO:0004645)
0.1 0.4 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.1 1.1 GO:0008430 selenium binding(GO:0008430)
0.1 0.6 GO:0019826 oxygen sensor activity(GO:0019826)
0.1 1.0 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 0.5 GO:0048495 Roundabout binding(GO:0048495)
0.1 0.2 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.1 0.2 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.5 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.2 GO:0035651 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.1 0.3 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0 0.1 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.0 0.2 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.4 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.5 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.2 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.4 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.4 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 1.0 GO:0015643 toxic substance binding(GO:0015643)
0.0 1.1 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.0 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 0.4 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.3 GO:0004797 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.0 0.2 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.4 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.5 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.4 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.6 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.1 GO:0015067 amidinotransferase activity(GO:0015067) glycine amidinotransferase activity(GO:0015068)
0.0 0.6 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.6 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.2 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 1.3 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.6 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 1.1 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 1.3 GO:0017166 vinculin binding(GO:0017166)
0.0 0.5 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.6 GO:0048185 activin binding(GO:0048185)
0.0 0.2 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.0 0.2 GO:0016015 morphogen activity(GO:0016015)
0.0 0.6 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.2 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 1.2 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.2 GO:0015350 methotrexate transporter activity(GO:0015350)
0.0 0.1 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.1 GO:0072510 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.0 0.3 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.3 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.7 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.7 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.2 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.0 0.9 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.5 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.2 GO:0098634 protein binding involved in cell-matrix adhesion(GO:0098634)
0.0 0.9 GO:0000217 DNA secondary structure binding(GO:0000217)
0.0 0.2 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.1 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.4 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.3 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.1 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.3 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.1 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0 0.7 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.4 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.2 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.2 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 0.3 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.2 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.5 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.2 GO:0045159 myosin II binding(GO:0045159)
0.0 0.4 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.1 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.0 1.2 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.3 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.4 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.1 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.8 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.0 0.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.5 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.3 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.6 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.1 GO:0036435 IkappaB kinase activity(GO:0008384) K48-linked polyubiquitin binding(GO:0036435)
0.0 0.5 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.3 GO:0043121 neurotrophin binding(GO:0043121)
0.0 0.2 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.7 GO:0017046 peptide hormone binding(GO:0017046)
0.0 0.6 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.0 GO:0071633 dihydroceramidase activity(GO:0071633)
0.0 0.1 GO:0019003 GDP binding(GO:0019003)
0.0 0.1 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.0 GO:0008520 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.0 0.1 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.0 0.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.1 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.3 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.0 0.1 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.0 0.1 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.0 0.2 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.3 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.1 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.1 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.2 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.7 GO:0016831 carboxy-lyase activity(GO:0016831)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.1 2.0 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.5 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.2 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 0.7 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 2.0 NABA COLLAGENS Genes encoding collagen proteins
0.0 2.1 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.4 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.1 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 1.5 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.2 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.2 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.9 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.1 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.1 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.2 PID MYC PATHWAY C-MYC pathway
0.0 0.5 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 1.6 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.4 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.4 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.5 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.7 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 1.0 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.6 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.3 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.4 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.7 ST GA13 PATHWAY G alpha 13 Pathway
0.0 0.3 PID ARF 3PATHWAY Arf1 pathway
0.0 0.4 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.4 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.2 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.2 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.1 1.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 0.1 REACTOME NUCLEOTIDE EXCISION REPAIR Genes involved in Nucleotide Excision Repair
0.1 1.8 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 0.9 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 0.3 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.1 1.6 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.7 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 2.3 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.6 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.6 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 1.9 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.3 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 1.2 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.8 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.4 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 0.9 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 1.3 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.5 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 1.0 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 1.9 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.6 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 1.1 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 3.0 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.6 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 2.3 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.7 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 1.3 REACTOME RNA POL III TRANSCRIPTION Genes involved in RNA Polymerase III Transcription
0.0 0.7 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.9 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.8 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.5 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.5 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 1.0 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.5 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.4 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.4 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.4 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.7 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 0.6 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.5 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.3 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.4 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.1 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.6 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.9 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.3 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.2 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.4 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.5 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.2 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions