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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for SPIB

Z-value: 1.14

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Transcription factors associated with SPIB

Gene Symbol Gene ID Gene Info
ENSG00000269404.2 Spi-B transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SPIBhg19_v2_chr19_+_50922187_50922215-0.366.4e-01Click!

Activity profile of SPIB motif

Sorted Z-values of SPIB motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_112016414 1.31 ENST00000343534.5
ENST00000369718.3
chromosome 1 open reading frame 162
chr11_-_64889252 0.74 ENST00000525297.1
ENST00000529259.1
Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed
chr8_-_101734170 0.50 ENST00000522387.1
ENST00000518196.1
poly(A) binding protein, cytoplasmic 1
chr14_+_96968802 0.45 ENST00000556619.1
ENST00000392990.2
poly(A) polymerase alpha
chr1_-_43282945 0.44 ENST00000537227.1
coiled-coil domain containing 23
chr17_+_65374075 0.42 ENST00000581322.1
phosphatidylinositol transfer protein, cytoplasmic 1
chr14_-_98444386 0.41 ENST00000556462.1
ENST00000556138.1
chromosome 14 open reading frame 64
chr8_+_74903580 0.41 ENST00000284818.2
ENST00000518893.1
lymphocyte antigen 96
chr7_-_112635675 0.39 ENST00000447785.1
ENST00000451962.1
AC018464.3
chr2_-_43019698 0.38 ENST00000431905.1
ENST00000294973.6
3-hydroxyanthranilate 3,4-dioxygenase
chr5_-_156390230 0.38 ENST00000407087.3
ENST00000274532.2
T-cell immunoglobulin and mucin domain containing 4
chr1_+_120839412 0.37 ENST00000355228.4
family with sequence similarity 72, member B
chr4_+_76871883 0.36 ENST00000599764.1
Uncharacterized protein
chr10_-_14596140 0.36 ENST00000496330.1
family with sequence similarity 107, member B
chr3_-_121379739 0.35 ENST00000428394.2
ENST00000314583.3
hematopoietic cell-specific Lyn substrate 1
chr19_-_9420249 0.35 ENST00000591998.1
zinc finger protein 699
chr7_+_23636992 0.35 ENST00000307471.3
ENST00000409765.1
coiled-coil domain containing 126
chr1_-_43637915 0.34 ENST00000236051.2
EBNA1 binding protein 2
chr8_-_101734308 0.34 ENST00000519004.1
ENST00000519363.1
ENST00000520142.1
poly(A) binding protein, cytoplasmic 1
chr14_+_102228123 0.34 ENST00000422945.2
ENST00000554442.1
ENST00000556260.2
ENST00000328724.5
ENST00000557268.1
protein phosphatase 2, regulatory subunit B', gamma
chr15_-_65809581 0.33 ENST00000341861.5
dipeptidyl-peptidase 8
chr1_-_17380630 0.32 ENST00000375499.3
succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
chr1_+_206138884 0.31 ENST00000341209.5
ENST00000607379.1
family with sequence similarity 72, member A
chr10_-_121302195 0.29 ENST00000369103.2
regulator of G-protein signaling 10
chr8_-_125551278 0.28 ENST00000519232.1
ENST00000523888.1
ENST00000522810.1
ENST00000519548.1
ENST00000517678.1
ENST00000605953.1
ENST00000276692.6
TatD DNase domain containing 1
chr14_+_96968707 0.28 ENST00000216277.8
ENST00000557320.1
ENST00000557471.1
poly(A) polymerase alpha
chr1_+_179851893 0.28 ENST00000531630.2
torsin A interacting protein 1
chr2_-_153573887 0.28 ENST00000493468.2
ENST00000545856.1
PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
chr19_+_42381337 0.28 ENST00000597454.1
ENST00000444740.2
CD79a molecule, immunoglobulin-associated alpha
chr5_+_96079240 0.28 ENST00000515663.1
calpastatin
chr3_+_23847432 0.28 ENST00000346855.3
ubiquitin-conjugating enzyme E2E 1
chr8_+_125860939 0.27 ENST00000525292.1
ENST00000528090.1
long intergenic non-protein coding RNA 964
chr1_-_43282906 0.27 ENST00000372521.4
coiled-coil domain containing 23
chr8_+_121457642 0.26 ENST00000305949.1
Mdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse) binding protein, 104kDa
chr1_-_31230650 0.26 ENST00000294507.3
lysosomal protein transmembrane 5
chr3_-_16554881 0.26 ENST00000451036.1
raftlin, lipid raft linker 1
chr9_-_127624194 0.26 ENST00000373570.4
ENST00000348462.3
ribosomal protein L35
chr16_+_28889801 0.26 ENST00000395503.4
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr1_-_43638168 0.26 ENST00000431635.2
EBNA1 binding protein 2
chr10_+_28822417 0.26 ENST00000428935.1
ENST00000420266.1
WW domain containing adaptor with coiled-coil
chr6_+_49431073 0.26 ENST00000335783.3
centromere protein Q
chr3_+_16926441 0.26 ENST00000418129.2
ENST00000396755.2
phospholipase C-like 2
chr11_-_10920838 0.26 ENST00000503469.2
CTD-2003C8.2
chr10_+_26727333 0.26 ENST00000356785.4
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr5_-_87980587 0.25 ENST00000509783.1
ENST00000509405.1
ENST00000506978.1
ENST00000509265.1
ENST00000513805.1
long intergenic non-protein coding RNA 461
chr17_-_8868991 0.25 ENST00000447110.1
phosphoinositide-3-kinase, regulatory subunit 5
chr17_+_65373531 0.25 ENST00000580974.1
phosphatidylinositol transfer protein, cytoplasmic 1
chr10_+_28822636 0.25 ENST00000442148.1
ENST00000448193.1
WW domain containing adaptor with coiled-coil
chr8_-_131028869 0.25 ENST00000518283.1
ENST00000519110.1
family with sequence similarity 49, member B
chrX_-_71497077 0.24 ENST00000373626.3
ribosomal protein S4, X-linked
chr4_-_47916543 0.24 ENST00000507489.1
nuclear transcription factor, X-box binding-like 1
chr2_-_231084820 0.23 ENST00000258382.5
ENST00000338556.3
SP110 nuclear body protein
chrX_+_123094369 0.23 ENST00000455404.1
ENST00000218089.9
stromal antigen 2
chr12_-_120663792 0.23 ENST00000546532.1
ENST00000548912.1
paxillin
chr8_+_98656693 0.23 ENST00000519934.1
metadherin
chr2_-_231084617 0.23 ENST00000409815.2
SP110 nuclear body protein
chr7_+_86781778 0.23 ENST00000432937.2
cyclin D binding myb-like transcription factor 1
chr15_-_65810042 0.22 ENST00000321147.6
dipeptidyl-peptidase 8
chr20_+_5931275 0.22 ENST00000378896.3
ENST00000378883.1
minichromosome maintenance complex component 8
chrX_+_123094672 0.22 ENST00000354548.5
ENST00000458700.1
stromal antigen 2
chr20_+_44486246 0.22 ENST00000255152.2
ENST00000454862.2
zinc finger, SWIM-type containing 3
chr1_+_14075865 0.22 ENST00000413440.1
PR domain containing 2, with ZNF domain
chr2_-_180871780 0.22 ENST00000410053.3
ENST00000295749.6
ENST00000404136.2
CWC22 spliceosome-associated protein homolog (S. cerevisiae)
chr5_+_102455853 0.22 ENST00000515845.1
ENST00000321521.9
ENST00000507921.1
diphosphoinositol pentakisphosphate kinase 2
chr11_-_61101247 0.21 ENST00000543627.1
damage-specific DNA binding protein 1, 127kDa
chr1_+_90287480 0.21 ENST00000394593.3
leucine rich repeat containing 8 family, member D
chr20_-_35274548 0.21 ENST00000262866.4
Src-like-adaptor 2
chr20_-_5931109 0.21 ENST00000203001.2
tRNA methyltransferase 6 homolog (S. cerevisiae)
chr7_-_37488547 0.21 ENST00000453399.1
engulfment and cell motility 1
chr5_+_95997769 0.21 ENST00000338252.3
ENST00000508830.1
calpastatin
chr1_-_156675368 0.21 ENST00000368222.3
cellular retinoic acid binding protein 2
chr15_+_43985725 0.20 ENST00000413453.2
creatine kinase, mitochondrial 1A
chr2_-_231084659 0.20 ENST00000258381.6
ENST00000358662.4
ENST00000455674.1
ENST00000392048.3
SP110 nuclear body protein
chr11_-_18548426 0.20 ENST00000357193.3
ENST00000536719.1
tumor susceptibility 101
chr11_-_116658695 0.20 ENST00000429220.1
ENST00000444935.1
zinc finger protein 259
chr2_+_109237717 0.20 ENST00000409441.1
LIM and senescent cell antigen-like domains 1
chr1_-_222886526 0.20 ENST00000541237.1
axin interactor, dorsalization associated
chr9_+_104296122 0.20 ENST00000389120.3
ring finger protein 20, E3 ubiquitin protein ligase
chr11_+_60145997 0.20 ENST00000530614.1
ENST00000530027.1
ENST00000530234.2
ENST00000528215.1
ENST00000531787.1
membrane-spanning 4-domains, subfamily A, member 7
membrane-spanning 4-domains, subfamily A, member 14
chr20_-_20033052 0.20 ENST00000536226.1
crooked neck pre-mRNA splicing factor 1
chr19_+_7413835 0.20 ENST00000576789.1
CTB-133G6.1
chr4_-_113437328 0.20 ENST00000313341.3
neurogenin 2
chr3_-_28390120 0.19 ENST00000334100.6
5-azacytidine induced 2
chr8_-_101962777 0.19 ENST00000395951.3
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr20_+_20033158 0.19 ENST00000340348.6
ENST00000377309.2
ENST00000389656.3
ENST00000377306.1
ENST00000245957.5
ENST00000377303.2
ENST00000475466.1
chromosome 20 open reading frame 26
chr12_-_51785182 0.19 ENST00000356317.3
ENST00000603188.1
ENST00000604847.1
ENST00000604506.1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6)
chr3_-_9291063 0.19 ENST00000383836.3
SLIT-ROBO Rho GTPase activating protein 3
chr15_+_91427691 0.19 ENST00000559355.1
ENST00000394302.1
feline sarcoma oncogene
chr15_+_86098670 0.19 ENST00000558811.1
A kinase (PRKA) anchor protein 13
chr11_-_47400062 0.19 ENST00000533030.1
spleen focus forming virus (SFFV) proviral integration oncogene
chr15_-_73925651 0.19 ENST00000545878.1
ENST00000287226.8
ENST00000345330.4
neuroplastin
chr2_-_152118276 0.19 ENST00000409092.1
RNA binding motif protein 43
chrX_-_11129229 0.19 ENST00000608176.1
ENST00000433747.2
ENST00000608576.1
ENST00000608916.1
RP11-120D5.1
chr1_+_24018269 0.19 ENST00000374550.3
ribosomal protein L11
chr12_-_8693539 0.19 ENST00000299663.3
C-type lectin domain family 4, member E
chr20_-_5931051 0.19 ENST00000453074.2
tRNA methyltransferase 6 homolog (S. cerevisiae)
chr16_+_71392616 0.19 ENST00000349553.5
ENST00000302628.4
ENST00000562305.1
calbindin 2
chr15_+_43886057 0.19 ENST00000441322.1
ENST00000413657.2
ENST00000453733.1
creatine kinase, mitochondrial 1B
chr7_-_37382683 0.19 ENST00000455879.1
engulfment and cell motility 1
chr2_+_135011731 0.19 ENST00000281923.2
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
chr1_+_151129135 0.18 ENST00000602841.1
sodium channel modifier 1
chr11_-_64512273 0.18 ENST00000377497.3
ENST00000377487.1
ENST00000430645.1
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chrX_+_11776410 0.18 ENST00000361672.2
male-specific lethal 3 homolog (Drosophila)
chr17_-_5138099 0.18 ENST00000571800.1
ENST00000574081.1
ENST00000399600.4
ENST00000574297.1
SLP adaptor and CSK interacting membrane protein
chr2_+_173940668 0.18 ENST00000375213.3
Mitogen-activated protein kinase kinase kinase MLT
chr2_+_233924548 0.18 ENST00000422935.1
inositol polyphosphate-5-phosphatase, 145kDa
chr19_-_3479086 0.18 ENST00000587847.1
chromosome 19 open reading frame 77
chr1_+_179851999 0.18 ENST00000527391.1
torsin A interacting protein 1
chr10_+_7830125 0.17 ENST00000335698.4
ENST00000541227.1
ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1
chr5_+_102455968 0.17 ENST00000358359.3
diphosphoinositol pentakisphosphate kinase 2
chrX_+_11777671 0.17 ENST00000380693.3
ENST00000380692.2
male-specific lethal 3 homolog (Drosophila)
chr1_-_143913143 0.17 ENST00000400889.1
family with sequence similarity 72, member D
chr14_+_63671105 0.17 ENST00000316754.3
ras homolog family member J
chr11_+_8704298 0.17 ENST00000531978.1
ENST00000524496.1
ENST00000532359.1
ENST00000530022.1
ribosomal protein L27a
chr3_+_100428316 0.17 ENST00000479672.1
ENST00000476228.1
ENST00000463568.1
TRK-fused gene
chr15_-_33360342 0.17 ENST00000558197.1
formin 1
chr14_-_45431091 0.17 ENST00000579157.1
ENST00000396128.4
ENST00000556500.1
kelch-like family member 28
chr19_-_15344243 0.17 ENST00000602233.1
epoxide hydrolase 3
chr14_+_45431379 0.17 ENST00000361577.3
ENST00000361462.2
ENST00000382233.2
family with sequence similarity 179, member B
chr20_+_5931497 0.17 ENST00000378886.2
ENST00000265187.4
minichromosome maintenance complex component 8
chr17_-_37009882 0.17 ENST00000378096.3
ENST00000394332.1
ENST00000394333.1
ENST00000577407.1
ENST00000479035.2
ribosomal protein L23
chr1_+_236305826 0.17 ENST00000366592.3
ENST00000366591.4
G protein-coupled receptor 137B
chr1_+_151682909 0.17 ENST00000326413.3
ENST00000442233.2
regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1
Uncharacterized protein; cDNA FLJ36032 fis, clone TESTI2017069
chr12_-_110939870 0.17 ENST00000447578.2
ENST00000546588.1
ENST00000360579.7
ENST00000549970.1
ENST00000549578.1
vacuolar protein sorting 29 homolog (S. cerevisiae)
chr11_-_116658758 0.17 ENST00000227322.3
zinc finger protein 259
chr15_+_51973550 0.17 ENST00000220478.3
secretogranin III
chr2_+_64751433 0.16 ENST00000238856.4
ENST00000422803.1
ENST00000238855.7
aftiphilin
chrX_+_11776701 0.16 ENST00000476743.1
ENST00000421368.2
ENST00000398527.2
male-specific lethal 3 homolog (Drosophila)
chr4_+_190861941 0.16 ENST00000226798.4
FSHD region gene 1
chr3_+_4535155 0.16 ENST00000544951.1
inositol 1,4,5-trisphosphate receptor, type 1
chr2_-_8723918 0.16 ENST00000454224.1
AC011747.4
chr16_+_19183671 0.16 ENST00000562711.2
synaptotagmin XVII
chr6_-_56708459 0.16 ENST00000370788.2
dystonin
chr2_+_233925038 0.16 ENST00000451407.1
inositol polyphosphate-5-phosphatase, 145kDa
chr10_-_7829909 0.16 ENST00000379562.4
ENST00000543003.1
ENST00000535925.1
KIN, antigenic determinant of recA protein homolog (mouse)
chr5_-_64858944 0.16 ENST00000508421.1
ENST00000510693.1
ENST00000514814.1
ENST00000515497.1
ENST00000396679.1
centromere protein K
chr3_-_116163830 0.16 ENST00000333617.4
limbic system-associated membrane protein
chr2_+_68592305 0.15 ENST00000234313.7
pleckstrin
chr12_-_15114658 0.15 ENST00000542276.1
Rho GDP dissociation inhibitor (GDI) beta
chr2_+_162087577 0.15 ENST00000439442.1
TRAF family member-associated NFKB activator
chr11_+_75110530 0.15 ENST00000531188.1
ENST00000530164.1
ENST00000422465.2
ENST00000278572.6
ENST00000534440.1
ENST00000527446.1
ENST00000526608.1
ENST00000527273.1
ENST00000524851.1
ribosomal protein S3
chr1_-_43855444 0.15 ENST00000372455.4
mediator complex subunit 8
chr10_+_7830092 0.15 ENST00000356708.7
ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1
chr12_-_9102224 0.15 ENST00000543845.1
ENST00000544245.1
mannose-6-phosphate receptor (cation dependent)
chr12_-_56120838 0.15 ENST00000548160.1
CD63 molecule
chr4_-_47916613 0.15 ENST00000381538.3
ENST00000329043.3
nuclear transcription factor, X-box binding-like 1
chr14_-_80678512 0.15 ENST00000553968.1
deiodinase, iodothyronine, type II
chr1_-_20446020 0.15 ENST00000375105.3
phospholipase A2, group IID
chr1_+_100818484 0.15 ENST00000544534.1
cell division cycle 14A
chr8_+_26434578 0.15 ENST00000493789.2
dihydropyrimidinase-like 2
chr3_+_100428188 0.15 ENST00000418917.2
ENST00000490574.1
TRK-fused gene
chr12_-_15114191 0.14 ENST00000541380.1
Rho GDP dissociation inhibitor (GDI) beta
chr9_-_14693417 0.14 ENST00000380916.4
zinc finger, DHHC-type containing 21
chr11_-_64512469 0.14 ENST00000377485.1
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr14_+_102276209 0.14 ENST00000445439.3
ENST00000334743.5
ENST00000557095.1
protein phosphatase 2, regulatory subunit B', gamma
chr2_+_173940163 0.14 ENST00000539448.1
Mitogen-activated protein kinase kinase kinase MLT
chr14_+_32546145 0.14 ENST00000556611.1
ENST00000539826.2
Rho GTPase activating protein 5
chr8_-_74206133 0.14 ENST00000352983.2
ribosomal protein L7
chr6_-_139308777 0.14 ENST00000529597.1
ENST00000415951.2
ENST00000367663.4
ENST00000409812.2
RALBP1 associated Eps domain containing 1
chr6_+_31554779 0.14 ENST00000376090.2
leukocyte specific transcript 1
chrX_+_11129388 0.14 ENST00000321143.4
ENST00000380763.3
ENST00000380762.4
holocytochrome c synthase
chr11_-_64889529 0.14 ENST00000531743.1
ENST00000527548.1
ENST00000526555.1
ENST00000279259.3
Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed
chr8_+_104426942 0.14 ENST00000297579.5
DDB1 and CUL4 associated factor 13
chr1_+_40505891 0.14 ENST00000372797.3
ENST00000372802.1
ENST00000449311.1
CAP, adenylate cyclase-associated protein 1 (yeast)
chr22_-_37640277 0.14 ENST00000401529.3
ENST00000249071.6
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr2_-_74405929 0.14 ENST00000396049.4
MOB kinase activator 1A
chr19_-_3478477 0.14 ENST00000591708.1
chromosome 19 open reading frame 77
chr3_+_28390637 0.14 ENST00000420223.1
ENST00000383768.2
zinc finger, CW type with PWWP domain 2
chr3_+_184529929 0.14 ENST00000287546.4
ENST00000437079.3
vacuolar protein sorting 8 homolog (S. cerevisiae)
chr2_+_233925064 0.14 ENST00000359570.5
ENST00000538935.1
inositol polyphosphate-5-phosphatase, 145kDa
chr4_+_86525299 0.14 ENST00000512201.1
Rho GTPase activating protein 24
chr2_-_188419200 0.14 ENST00000233156.3
ENST00000426055.1
ENST00000453013.1
ENST00000417013.1
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr5_-_140013241 0.13 ENST00000519715.1
CD14 molecule
chr15_-_65809991 0.13 ENST00000559526.1
ENST00000358939.4
ENST00000560665.1
ENST00000321118.7
ENST00000339244.5
ENST00000300141.6
dipeptidyl-peptidase 8
chr10_+_94590910 0.13 ENST00000371547.4
exocyst complex component 6
chr16_-_4850471 0.13 ENST00000592019.1
ENST00000586153.1
rogdi homolog (Drosophila)
chr9_-_130541017 0.13 ENST00000314830.8
SH2 domain containing 3C
chr2_-_188419078 0.13 ENST00000437725.1
ENST00000409676.1
ENST00000339091.4
ENST00000420747.1
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr2_+_202125219 0.13 ENST00000323492.7
caspase 8, apoptosis-related cysteine peptidase
chr1_+_104068312 0.13 ENST00000524631.1
ENST00000531883.1
ENST00000533099.1
ENST00000527062.1
RNA-binding region (RNP1, RRM) containing 3
chr1_+_154193643 0.13 ENST00000456325.1
ubiquitin associated protein 2-like
chr11_-_47399942 0.13 ENST00000227163.4
spleen focus forming virus (SFFV) proviral integration oncogene
chr1_+_222886694 0.13 ENST00000426638.1
ENST00000537020.1
ENST00000539697.1
BRO1 domain and CAAX motif containing
chr6_-_11382478 0.13 ENST00000397378.3
ENST00000513989.1
ENST00000508546.1
ENST00000504387.1
neural precursor cell expressed, developmentally down-regulated 9
chr14_-_50319758 0.13 ENST00000298310.5
nuclear export mediator factor
chr1_+_154193325 0.13 ENST00000428931.1
ENST00000441890.1
ENST00000271877.7
ENST00000412596.1
ENST00000368504.1
ENST00000437652.1
ubiquitin associated protein 2-like
chr3_+_239652 0.13 ENST00000435603.1
cell adhesion molecule L1-like
chr6_+_31554826 0.13 ENST00000376089.2
ENST00000396112.2
leukocyte specific transcript 1
chr3_-_28390298 0.13 ENST00000457172.1
5-azacytidine induced 2
chr9_+_104296243 0.13 ENST00000466817.1
ring finger protein 20, E3 ubiquitin protein ligase
chr4_-_103266626 0.13 ENST00000356736.4
solute carrier family 39 (zinc transporter), member 8
chr14_-_50319482 0.13 ENST00000546046.1
ENST00000555970.1
ENST00000554626.1
ENST00000545773.1
ENST00000556672.1
nuclear export mediator factor
chr7_+_23145884 0.13 ENST00000409689.1
ENST00000410047.1
kelch-like family member 7
chr4_+_103423055 0.13 ENST00000505458.1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr16_+_28889703 0.13 ENST00000357084.3
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr4_+_95129061 0.13 ENST00000354268.4
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr1_+_159272111 0.13 ENST00000368114.1
Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
chr15_+_43885252 0.13 ENST00000453782.1
ENST00000300283.6
ENST00000437924.1
ENST00000450086.2
creatine kinase, mitochondrial 1B
chr17_-_7835228 0.13 ENST00000303731.4
ENST00000571947.1
ENST00000540486.1
ENST00000572656.1
trafficking protein particle complex 1
chr10_-_65028817 0.13 ENST00000542921.1
jumonji domain containing 1C

Network of associatons between targets according to the STRING database.

First level regulatory network of SPIB

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0031443 fast-twitch skeletal muscle fiber contraction(GO:0031443)
0.1 0.5 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.1 0.4 GO:0044027 DNA hypermethylation(GO:0044026) hypermethylation of CpG island(GO:0044027)
0.1 0.5 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.1 0.4 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.1 0.4 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.1 0.3 GO:0032752 positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401)
0.1 0.5 GO:0071461 cellular response to redox state(GO:0071461)
0.1 0.2 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774) regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.1 0.5 GO:0044565 dendritic cell proliferation(GO:0044565)
0.1 0.3 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.1 0.6 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 0.2 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.1 0.7 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 0.4 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.1 0.3 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.1 0.2 GO:1905051 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.0 0.3 GO:0072092 ureteric bud invasion(GO:0072092)
0.0 0.2 GO:2000434 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.0 0.6 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.3 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.3 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.0 0.1 GO:0045083 negative regulation of interleukin-12 biosynthetic process(GO:0045083)
0.0 0.1 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.0 0.4 GO:2001168 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.0 0.1 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.0 0.5 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.1 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.0 0.3 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 0.2 GO:0071725 toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.0 0.1 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051) regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0 0.5 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.2 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0 0.1 GO:0032672 natural killer cell tolerance induction(GO:0002519) regulation of tolerance induction dependent upon immune response(GO:0002652) regulation of interleukin-3 production(GO:0032672)
0.0 0.1 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.0 0.3 GO:0033523 histone H2B ubiquitination(GO:0033523)
0.0 0.3 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.0 0.1 GO:0002522 leukocyte migration involved in immune response(GO:0002522)
0.0 0.2 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.2 GO:0097473 cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.0 0.1 GO:0031642 negative regulation of myelination(GO:0031642)
0.0 0.3 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.1 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.0 0.1 GO:0052056 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.0 0.5 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0 0.2 GO:1905244 regulation of modification of synaptic structure(GO:1905244)
0.0 0.1 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.8 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.1 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.0 0.2 GO:0033625 positive regulation of integrin activation(GO:0033625)
0.0 0.3 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.1 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.0 0.3 GO:0006105 succinate metabolic process(GO:0006105)
0.0 0.3 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.0 0.2 GO:2000680 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.0 0.2 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.3 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.4 GO:0008340 determination of adult lifespan(GO:0008340)
0.0 0.4 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.2 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.0 0.1 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.1 GO:0033590 response to cobalamin(GO:0033590) cellular response to erythropoietin(GO:0036018)
0.0 0.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.1 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.0 0.0 GO:0045588 positive regulation of gamma-delta T cell differentiation(GO:0045588)
0.0 0.0 GO:0031296 B cell costimulation(GO:0031296)
0.0 0.3 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.7 GO:0031440 regulation of mRNA 3'-end processing(GO:0031440)
0.0 0.1 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
0.0 0.3 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0 0.2 GO:0051480 regulation of cytosolic calcium ion concentration(GO:0051480)
0.0 0.1 GO:0061198 fungiform papilla formation(GO:0061198)
0.0 0.2 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.1 GO:2000567 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.0 0.1 GO:0042335 cuticle development(GO:0042335)
0.0 0.1 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.1 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.0 GO:0042144 vacuole fusion, non-autophagic(GO:0042144)
0.0 0.2 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.1 GO:0015691 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0 0.2 GO:0050849 negative regulation of calcium-mediated signaling(GO:0050849)
0.0 0.4 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.1 GO:0090487 toxin catabolic process(GO:0009407) secondary metabolite catabolic process(GO:0090487)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0019815 B cell receptor complex(GO:0019815)
0.1 0.3 GO:0045281 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1 0.4 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.1 0.4 GO:0097362 MCM8-MCM9 complex(GO:0097362)
0.1 0.6 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.2 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.1 0.2 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.1 0.6 GO:0072487 MSL complex(GO:0072487)
0.0 0.2 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.0 0.3 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.3 GO:0031673 H zone(GO:0031673)
0.0 0.4 GO:0033503 HULC complex(GO:0033503)
0.0 0.2 GO:0071159 NF-kappaB complex(GO:0071159)
0.0 0.2 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.1 GO:0043614 multi-eIF complex(GO:0043614) translation preinitiation complex(GO:0070993)
0.0 0.3 GO:0033263 CORVET complex(GO:0033263)
0.0 0.1 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0 0.4 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.3 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.2 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.0 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.2 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.1 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.0 0.1 GO:0043196 varicosity(GO:0043196)
0.0 0.7 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.2 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.4 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.6 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.3 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.5 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.1 GO:0032044 DSIF complex(GO:0032044)
0.0 0.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.1 GO:0060091 kinocilium(GO:0060091)
0.0 0.2 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.1 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.0 0.3 GO:0070971 endoplasmic reticulum exit site(GO:0070971)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177) 3 iron, 4 sulfur cluster binding(GO:0051538)
0.1 0.2 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.1 0.4 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.1 0.7 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.1 0.5 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.1 0.3 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 0.7 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.4 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.4 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.5 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.4 GO:0055104 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.0 0.1 GO:0030626 U12 snRNA binding(GO:0030626)
0.0 0.2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.5 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.4 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.7 GO:0008494 translation activator activity(GO:0008494)
0.0 0.3 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.3 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.7 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.2 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:0019863 IgE binding(GO:0019863)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.4 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.1 GO:0045174 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.0 0.1 GO:0022897 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0 0.2 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.1 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.1 GO:0052812 phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.0 0.1 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.0 0.2 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.3 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.6 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.6 GO:0005521 lamin binding(GO:0005521)
0.0 0.2 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.1 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.1 GO:0023030 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.0 0.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.1 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993) amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.4 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0 0.2 GO:0032357 oxidized purine DNA binding(GO:0032357)
0.0 0.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.2 GO:0019841 retinol binding(GO:0019841)
0.0 0.0 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.0 0.1 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.1 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.3 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.1 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.2 GO:0035325 Toll-like receptor binding(GO:0035325)
0.0 0.1 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.3 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.1 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.3 GO:0097602 cullin family protein binding(GO:0097602)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.7 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.4 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.7 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.1 REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.0 0.2 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.4 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.3 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 1.7 REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.0 0.1 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.3 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.1 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.2 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.4 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.5 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)