Project

A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

Navigation
Downloads

Results for SREBF1_TFE3

Z-value: 2.25

Motif logo

Transcription factors associated with SREBF1_TFE3

Gene Symbol Gene ID Gene Info
ENSG00000072310.12 sterol regulatory element binding transcription factor 1
ENSG00000068323.12 transcription factor binding to IGHM enhancer 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SREBF1hg19_v2_chr17_-_17726907_177269580.963.5e-02Click!
TFE3hg19_v2_chrX_-_48901012_489010500.861.4e-01Click!

Activity profile of SREBF1_TFE3 motif

Sorted Z-values of SREBF1_TFE3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_7137857 4.33 ENST00000005340.5
dishevelled segment polarity protein 2
chr17_-_7137582 2.99 ENST00000575756.1
ENST00000575458.1
dishevelled segment polarity protein 2
chr16_+_2570340 2.96 ENST00000568263.1
ENST00000293971.6
ENST00000302956.4
ENST00000413459.3
ENST00000566706.1
ENST00000569879.1
amidohydrolase domain containing 2
chr1_+_44440575 2.79 ENST00000532642.1
ENST00000236067.4
ENST00000471859.2
ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
chr17_+_42422629 2.67 ENST00000589536.1
ENST00000587109.1
ENST00000587518.1
granulin
chr11_-_1785139 2.66 ENST00000236671.2
cathepsin D
chr17_+_78075361 2.45 ENST00000577106.1
ENST00000390015.3
glucosidase, alpha; acid
chr19_+_49458107 2.38 ENST00000539787.1
ENST00000345358.7
ENST00000391871.3
ENST00000415969.2
ENST00000354470.3
ENST00000506183.1
ENST00000293288.8
BCL2-associated X protein
chr17_+_78075324 2.32 ENST00000570803.1
glucosidase, alpha; acid
chr2_-_220042825 2.28 ENST00000409789.1
cyclin Pas1/PHO80 domain containing 1
chr3_+_19988736 2.06 ENST00000443878.1
RAB5A, member RAS oncogene family
chr17_+_42422662 2.02 ENST00000593167.1
ENST00000585512.1
ENST00000591740.1
ENST00000592783.1
ENST00000587387.1
ENST00000588237.1
ENST00000589265.1
granulin
chr19_-_36545649 1.97 ENST00000292894.1
THAP domain containing 8
chr12_+_112451222 1.96 ENST00000552052.1
endoplasmic reticulum protein 29
chr17_+_78075498 1.95 ENST00000302262.3
glucosidase, alpha; acid
chr16_+_28986134 1.94 ENST00000352260.7
spinster homolog 1 (Drosophila)
chr19_-_36545128 1.93 ENST00000538849.1
THAP domain containing 8
chr16_-_5083917 1.91 ENST00000312251.3
ENST00000381955.3
N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr22_-_39268192 1.89 ENST00000216083.6
chromobox homolog 6
chr17_+_62223320 1.78 ENST00000580828.1
ENST00000582965.1
small nucleolar RNA, H/ACA box 76
chr7_+_4815238 1.74 ENST00000348624.4
ENST00000401897.1
adaptor-related protein complex 5, zeta 1 subunit
chr16_+_28986085 1.66 ENST00000565975.1
ENST00000311008.11
ENST00000323081.8
ENST00000334536.8
spinster homolog 1 (Drosophila)
chr12_+_51633061 1.65 ENST00000551313.1
DAZ associated protein 2
chr19_+_5681153 1.64 ENST00000579559.1
ENST00000577222.1
hydroxysteroid (11-beta) dehydrogenase 1-like
ribosomal protein L36
chr5_-_176730733 1.61 ENST00000504395.1
RAB24, member RAS oncogene family
chr6_-_33385854 1.59 ENST00000488478.1
cutA divalent cation tolerance homolog (E. coli)
chr6_-_44225231 1.57 ENST00000538577.1
ENST00000537814.1
ENST00000393810.1
ENST00000393812.3
solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2
chr17_+_1627834 1.56 ENST00000419248.1
ENST00000418841.1
WD repeat domain 81
chr12_-_58146048 1.56 ENST00000547281.1
ENST00000546489.1
ENST00000552388.1
ENST00000540325.1
ENST00000312990.6
cyclin-dependent kinase 4
chr17_-_6915646 1.56 ENST00000574377.1
ENST00000399541.2
ENST00000399540.2
ENST00000575727.1
ENST00000573939.1
Uncharacterized protein
chr16_-_1525016 1.55 ENST00000262318.8
ENST00000448525.1
chloride channel, voltage-sensitive 7
chr4_-_75024085 1.55 ENST00000600169.1
Uncharacterized protein
chr12_+_51632638 1.52 ENST00000549732.2
DAZ associated protein 2
chr22_-_39268308 1.48 ENST00000407418.3
chromobox homolog 6
chr7_+_916183 1.47 ENST00000265857.3
golgi to ER traffic protein 4 homolog (S. cerevisiae)
chr17_+_6915730 1.46 ENST00000548577.1
ribonuclease, RNase K
chr11_-_71814422 1.44 ENST00000278671.5
late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
chr20_-_36156125 1.44 ENST00000397135.1
ENST00000397137.1
bladder cancer associated protein
chr11_+_67159416 1.43 ENST00000307980.2
ENST00000544620.1
RAD9 homolog A (S. pombe)
chr14_-_20922960 1.43 ENST00000553640.1
ENST00000488532.2
O-sialoglycoprotein endopeptidase
chr19_-_5680891 1.42 ENST00000309324.4
chromosome 19 open reading frame 70
chr17_+_42422637 1.42 ENST00000053867.3
ENST00000588143.1
granulin
chr17_-_79791118 1.39 ENST00000576431.1
ENST00000575061.1
ENST00000455127.2
ENST00000572645.1
ENST00000538396.1
ENST00000573478.1
family with sequence similarity 195, member B
chr19_-_49016847 1.38 ENST00000598924.1
CTC-273B12.10
chr19_-_10764509 1.37 ENST00000591501.1
ILF3 antisense RNA 1 (head to head)
chr16_+_2570431 1.36 ENST00000563556.1
amidohydrolase domain containing 2
chr11_+_62538775 1.35 ENST00000294168.3
ENST00000526261.1
TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
chr16_-_5083589 1.34 ENST00000563578.1
ENST00000562346.2
N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr1_+_45477901 1.32 ENST00000434478.1
uroporphyrinogen decarboxylase
chr1_+_11796177 1.31 ENST00000400895.2
ENST00000376629.4
ENST00000376627.2
ENST00000314340.5
ENST00000452018.2
ENST00000510878.1
angiotensin II receptor-associated protein
chr5_+_149865377 1.30 ENST00000522491.1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr19_+_10764937 1.27 ENST00000449870.1
ENST00000318511.3
ENST00000420083.1
interleukin enhancer binding factor 3, 90kDa
chr3_-_4508925 1.25 ENST00000534863.1
ENST00000383843.5
ENST00000458465.2
ENST00000405420.2
ENST00000272902.5
sulfatase modifying factor 1
chr19_+_40854363 1.23 ENST00000599685.1
ENST00000392032.2
phospholipase D family, member 3
chr14_+_23790655 1.22 ENST00000397276.2
poly(A) binding protein, nuclear 1
chr17_+_6915798 1.22 ENST00000402093.1
ribonuclease, RNase K
chr17_-_18266818 1.19 ENST00000583780.1
serine hydroxymethyltransferase 1 (soluble)
chr17_-_6915616 1.19 ENST00000575889.1
Uncharacterized protein
chr16_-_28503357 1.15 ENST00000333496.9
ENST00000561505.1
ENST00000567963.1
ENST00000354630.5
ENST00000355477.5
ENST00000357076.5
ENST00000565688.1
ENST00000359984.7
ceroid-lipofuscinosis, neuronal 3
chr14_-_20929624 1.13 ENST00000398020.4
ENST00000250489.4
transmembrane protein 55B
chr5_+_149340339 1.13 ENST00000433184.1
solute carrier family 26 (anion exchanger), member 2
chr2_+_220042933 1.12 ENST00000430297.2
family with sequence similarity 134, member A
chr1_+_11796126 1.11 ENST00000376637.3
angiotensin II receptor-associated protein
chr20_-_44519839 1.08 ENST00000372518.4
neuralized E3 ubiquitin protein ligase 2
chr5_-_133706695 1.07 ENST00000521755.1
ENST00000523054.1
ENST00000435240.2
ENST00000609654.1
ENST00000536186.1
ENST00000609383.1
cyclin-dependent kinase-like 3
chr19_+_6464243 1.07 ENST00000600229.1
ENST00000356762.3
crumbs homolog 3 (Drosophila)
chr12_+_51632666 1.06 ENST00000604900.1
DAZ associated protein 2
chr20_+_44520009 1.05 ENST00000607482.1
ENST00000372459.2
cathepsin A
chr17_-_58469591 1.05 ENST00000589335.1
ubiquitin specific peptidase 32
chr19_+_40873617 1.05 ENST00000599353.1
phospholipase D family, member 3
chr17_+_6915902 1.05 ENST00000570898.1
ENST00000552842.1
ribonuclease, RNase K
chr19_+_10765003 1.04 ENST00000407004.3
ENST00000589998.1
ENST00000589600.1
interleukin enhancer binding factor 3, 90kDa
chr20_-_2821271 1.04 ENST00000448755.1
ENST00000360652.2
PC-esterase domain containing 1A
chr14_-_21852119 1.04 ENST00000555943.1
suppressor of Ty 16 homolog (S. cerevisiae)
chr15_-_52971544 1.02 ENST00000566768.1
ENST00000561543.1
family with sequence similarity 214, member A
chr1_-_153940097 1.01 ENST00000413622.1
ENST00000310483.6
solute carrier family 39 (zinc transporter), member 1
chr7_+_100464760 1.01 ENST00000200457.4
thyroid hormone receptor interactor 6
chr20_-_36156264 1.00 ENST00000445723.1
ENST00000414080.1
bladder cancer associated protein
chr9_-_131709858 0.99 ENST00000372586.3
dolichol kinase
chr1_-_154193091 0.98 ENST00000362076.4
ENST00000350592.3
ENST00000368516.1
chromosome 1 open reading frame 43
chr19_-_15236173 0.97 ENST00000527093.1
ilvB (bacterial acetolactate synthase)-like
chr6_-_43197189 0.97 ENST00000509253.1
ENST00000393987.2
ENST00000230431.6
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
chr19_-_55895966 0.96 ENST00000444469.3
transmembrane protein 238
chr2_-_176867534 0.95 ENST00000445472.1
KIAA1715
chr12_-_58146128 0.95 ENST00000551800.1
ENST00000549606.1
ENST00000257904.6
cyclin-dependent kinase 4
chr2_-_47572207 0.94 ENST00000441997.1
AC073283.4
chr3_+_127317705 0.94 ENST00000480910.1
minichromosome maintenance complex component 2
chr12_-_108154705 0.93 ENST00000547188.1
PR domain containing 4
chr9_-_34665983 0.93 ENST00000416454.1
ENST00000544078.2
ENST00000421828.2
ENST00000423809.1
HCG2040265, isoform CRA_a; Uncharacterized protein; cDNA FLJ50015
chr16_+_4421841 0.92 ENST00000304735.3
vasorin
chr7_-_150777874 0.92 ENST00000540185.1
Fas-activated serine/threonine kinase
chr19_-_15236470 0.91 ENST00000533747.1
ENST00000598709.1
ENST00000534378.1
ilvB (bacterial acetolactate synthase)-like
chr1_-_11866034 0.91 ENST00000376590.3
methylenetetrahydrofolate reductase (NAD(P)H)
chr19_-_15236562 0.91 ENST00000263383.3
ilvB (bacterial acetolactate synthase)-like
chr1_+_221051699 0.90 ENST00000366903.6
H2.0-like homeobox
chr7_+_150759634 0.90 ENST00000392826.2
ENST00000461735.1
solute carrier family 4 (anion exchanger), member 2
chr2_+_26987111 0.90 ENST00000344420.5
ENST00000416475.2
solute carrier family 35, member F6
chr12_+_6833323 0.87 ENST00000544725.1
COP9 signalosome subunit 7A
chr4_-_83295296 0.87 ENST00000507010.1
ENST00000503822.1
heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
chr16_-_1401799 0.86 ENST00000007390.2
TSR3, 20S rRNA accumulation, homolog (S. cerevisiae)
chr16_+_28985542 0.85 ENST00000567771.1
ENST00000568388.1
spinster homolog 1 (Drosophila)
chr8_+_9009296 0.84 ENST00000521718.1
Uncharacterized protein
chr12_+_113796347 0.84 ENST00000545182.2
ENST00000280800.3
phospholipase B domain containing 2
chr19_+_40854559 0.84 ENST00000598962.1
ENST00000409419.1
ENST00000409587.1
ENST00000602131.1
ENST00000409735.4
ENST00000600948.1
ENST00000356508.5
ENST00000596682.1
ENST00000594908.1
phospholipase D family, member 3
chr19_-_47734448 0.83 ENST00000439096.2
BCL2 binding component 3
chr12_+_57916466 0.83 ENST00000355673.3
methyl-CpG binding domain protein 6
chr9_+_131799213 0.82 ENST00000358369.4
ENST00000406926.2
ENST00000277475.5
ENST00000450073.1
family with sequence similarity 73, member B
chr16_-_88923285 0.81 ENST00000542788.1
ENST00000569433.1
ENST00000268695.5
ENST00000568311.1
galactosamine (N-acetyl)-6-sulfate sulfatase
chr3_+_50654821 0.80 ENST00000457064.1
mitogen-activated protein kinase-activated protein kinase 3
chr19_-_4670345 0.80 ENST00000599630.1
ENST00000262947.3
chromosome 19 open reading frame 10
chr20_-_36156293 0.79 ENST00000373537.2
ENST00000414542.2
bladder cancer associated protein
chr7_+_102073966 0.78 ENST00000495936.1
ENST00000356387.2
ENST00000478730.2
ENST00000468241.1
ENST00000403646.3
ORAI calcium release-activated calcium modulator 2
chr16_-_30366672 0.78 ENST00000305596.3
CD2 (cytoplasmic tail) binding protein 2
chr2_+_120187465 0.78 ENST00000409826.1
ENST00000417645.1
transmembrane protein 37
chr22_+_35776828 0.78 ENST00000216117.8
heme oxygenase (decycling) 1
chr16_-_67190152 0.77 ENST00000486556.1
TNFRSF1A-associated via death domain
chr17_+_46970134 0.77 ENST00000503641.1
ENST00000514808.1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr11_+_63706444 0.76 ENST00000377793.4
ENST00000456907.2
ENST00000539656.1
N(alpha)-acetyltransferase 40, NatD catalytic subunit
chr12_+_53645870 0.76 ENST00000329548.4
major facilitator superfamily domain containing 5
chrX_+_153657009 0.75 ENST00000449556.1
ATPase, H+ transporting, lysosomal accessory protein 1
chr16_-_28503080 0.74 ENST00000565316.1
ENST00000565778.1
ENST00000357857.9
ENST00000568558.1
ENST00000357806.7
ceroid-lipofuscinosis, neuronal 3
chr22_-_42342692 0.74 ENST00000404067.1
ENST00000402338.1
centromere protein M
chr19_+_56166360 0.73 ENST00000308924.4
U2 small nuclear RNA auxiliary factor 2
chr19_-_41256207 0.73 ENST00000598485.2
ENST00000470681.1
ENST00000339153.3
ENST00000598729.1
chromosome 19 open reading frame 54
chr3_+_51428704 0.73 ENST00000323686.4
RNA binding motif protein 15B
chr16_-_28503327 0.73 ENST00000535392.1
ENST00000395653.4
ceroid-lipofuscinosis, neuronal 3
chr5_+_150827143 0.72 ENST00000243389.3
ENST00000517945.1
ENST00000521925.1
solute carrier family 36 (proton/amino acid symporter), member 1
chr4_+_17616253 0.72 ENST00000237380.7
mediator complex subunit 28
chr1_-_154193009 0.72 ENST00000368518.1
ENST00000368519.1
ENST00000368521.5
chromosome 1 open reading frame 43
chr14_-_54955376 0.71 ENST00000553333.1
glia maturation factor, beta
chr2_-_47572105 0.71 ENST00000419035.1
ENST00000448713.1
ENST00000450550.1
ENST00000413185.2
AC073283.4
chr2_+_240323439 0.70 ENST00000428471.1
ENST00000413029.1
Uncharacterized protein
chr19_+_46009837 0.69 ENST00000589627.1
vasodilator-stimulated phosphoprotein
chr8_-_103876340 0.69 ENST00000518353.1
antizyme inhibitor 1
chr8_+_109455830 0.69 ENST00000524143.1
ER membrane protein complex subunit 2
chr19_+_14544099 0.68 ENST00000242783.6
ENST00000586557.1
ENST00000590097.1
protein kinase N1
chr1_-_154928562 0.68 ENST00000368463.3
ENST00000539880.1
ENST00000542459.1
ENST00000368460.3
ENST00000368465.1
pre-B-cell leukemia homeobox interacting protein 1
chr14_+_35591020 0.68 ENST00000603611.1
KIAA0391
chr19_-_49016418 0.68 ENST00000270238.3
lemur tyrosine kinase 3
chr15_-_72668805 0.67 ENST00000268097.5
hexosaminidase A (alpha polypeptide)
chr17_+_46018872 0.67 ENST00000583599.1
ENST00000434554.2
ENST00000225573.4
ENST00000544840.1
ENST00000534893.1
pyridoxamine 5'-phosphate oxidase
chr10_+_102759045 0.67 ENST00000370220.1
leucine zipper, putative tumor suppressor 2
chr9_-_138391692 0.66 ENST00000429260.2
chromosome 9 open reading frame 116
chr1_-_21995794 0.66 ENST00000542643.2
ENST00000374765.4
ENST00000317967.7
RAP1 GTPase activating protein
chrX_+_100878112 0.66 ENST00000491568.2
ENST00000479298.1
armadillo repeat containing, X-linked 3
chr22_-_20850128 0.65 ENST00000328879.4
kelch-like family member 22
chr5_-_176730676 0.65 ENST00000393611.2
ENST00000303251.6
ENST00000303270.6
RAB24, member RAS oncogene family
chr10_+_102756800 0.63 ENST00000370223.3
leucine zipper, putative tumor suppressor 2
chr16_+_69796209 0.63 ENST00000359154.2
ENST00000561780.1
ENST00000563659.1
ENST00000448661.1
WW domain containing E3 ubiquitin protein ligase 2
chr22_-_36903069 0.63 ENST00000216187.6
ENST00000423980.1
FAD-dependent oxidoreductase domain containing 2
chr16_+_21623958 0.63 ENST00000568826.1
methyltransferase like 9
chr13_+_113951532 0.62 ENST00000332556.4
lysosomal-associated membrane protein 1
chr19_-_40854281 0.62 ENST00000392035.2
chromosome 19 open reading frame 47
chr14_-_68283291 0.62 ENST00000555452.1
ENST00000347230.4
zinc finger, FYVE domain containing 26
chr16_+_4897632 0.61 ENST00000262376.6
ubinuclein 1
chr16_+_50280020 0.61 ENST00000564965.1
adenylate cyclase 7
chr18_-_33047039 0.60 ENST00000591141.1
ENST00000586741.1
RP11-322E11.5
chr1_-_204329013 0.60 ENST00000272203.3
ENST00000414478.1
pleckstrin homology domain containing, family A member 6
chr14_+_24458093 0.60 ENST00000558753.1
ENST00000537912.1
dehydrogenase/reductase (SDR family) member 4 like 2
chr7_-_55583740 0.60 ENST00000453256.1
vesicular, overexpressed in cancer, prosurvival protein 1
chr7_-_150777949 0.60 ENST00000482571.1
Fas-activated serine/threonine kinase
chr17_+_39411636 0.60 ENST00000394008.1
keratin associated protein 9-9
chr5_-_175964366 0.60 ENST00000274811.4
ring finger protein 44
chr2_+_111880242 0.59 ENST00000393252.3
BCL2-like 11 (apoptosis facilitator)
chr6_-_43484621 0.59 ENST00000506469.1
ENST00000503972.1
Yip1 domain family, member 3
chr1_-_154909329 0.58 ENST00000368467.3
phosphomevalonate kinase
chr22_-_29663690 0.58 ENST00000406335.1
rhomboid domain containing 3
chr16_+_88636875 0.58 ENST00000569435.1
zinc finger CCCH-type containing 18
chr18_+_20715416 0.58 ENST00000580153.1
Cdk5 and Abl enzyme substrate 1
chr7_+_99954224 0.58 ENST00000608825.1
paired immunoglobin-like type 2 receptor beta
chr19_-_40324767 0.57 ENST00000601972.1
ENST00000430012.2
ENST00000323039.5
ENST00000348817.3
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
chr15_+_101417919 0.57 ENST00000561338.1
aldehyde dehydrogenase 1 family, member A3
chr22_+_31002990 0.57 ENST00000423350.1
transcobalamin II
chr17_+_46970127 0.57 ENST00000355938.5
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr22_+_40573921 0.57 ENST00000454349.2
ENST00000335727.9
trinucleotide repeat containing 6B
chrX_+_54466829 0.57 ENST00000375151.4
TSR2, 20S rRNA accumulation, homolog (S. cerevisiae)
chr11_+_66360665 0.56 ENST00000310190.4
copper chaperone for superoxide dismutase
chr15_+_91418918 0.56 ENST00000560824.1
furin (paired basic amino acid cleaving enzyme)
chr11_-_61684962 0.56 ENST00000394836.2
RAB3A interacting protein (rabin3)-like 1
chr12_+_51632600 0.56 ENST00000549555.1
ENST00000439799.2
ENST00000425012.2
DAZ associated protein 2
chr1_+_154975110 0.56 ENST00000535420.1
ENST00000368426.3
zinc finger and BTB domain containing 7B
chr7_+_99699280 0.55 ENST00000421755.1
adaptor-related protein complex 4, mu 1 subunit
chr1_+_179051160 0.55 ENST00000367625.4
ENST00000352445.6
torsin family 3, member A
chr19_-_3500635 0.55 ENST00000250937.3
deoxyhypusine hydroxylase/monooxygenase
chr12_+_56110315 0.55 ENST00000548556.1
biogenesis of lysosomal organelles complex-1, subunit 1
chr2_-_131099897 0.55 ENST00000409127.1
ENST00000437688.2
ENST00000259229.2
coiled-coil domain containing 115
chr18_+_44497455 0.54 ENST00000592005.1
katanin p60 subunit A-like 2
chr3_-_135915146 0.54 ENST00000473093.1
male-specific lethal 2 homolog (Drosophila)
chr16_-_88878305 0.54 ENST00000569616.1
ENST00000563655.1
ENST00000567713.1
ENST00000426324.2
ENST00000378364.3
adenine phosphoribosyltransferase
chr11_+_61560348 0.54 ENST00000535723.1
ENST00000574708.1
flap structure-specific endonuclease 1
fatty acid desaturase 2
chr19_-_1237990 0.54 ENST00000382477.2
ENST00000215376.6
ENST00000590083.1
chromosome 19 open reading frame 26
chr15_-_72668185 0.54 ENST00000457859.2
ENST00000566304.1
ENST00000567159.1
ENST00000429918.2
hexosaminidase A (alpha polypeptide)
chr7_-_1595871 0.53 ENST00000319010.5
transmembrane protein 184A
chr4_-_100871506 0.53 ENST00000296417.5
H2A histone family, member Z
chr9_+_131084815 0.53 ENST00000300452.3
ENST00000609948.1
coenzyme Q4
chr11_+_64073022 0.52 ENST00000406310.1
ENST00000000442.6
ENST00000539594.1
estrogen-related receptor alpha
chr7_+_97910962 0.52 ENST00000539286.1
brain protein I3
chr2_-_198364552 0.52 ENST00000439605.1
ENST00000418022.1
heat shock 60kDa protein 1 (chaperonin)
chr17_+_40688190 0.52 ENST00000225927.2
N-acetylglucosaminidase, alpha
chr6_+_42018614 0.52 ENST00000465926.1
ENST00000482432.1
TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa

Network of associatons between targets according to the STRING database.

First level regulatory network of SREBF1_TFE3

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 6.7 GO:0043181 vacuolar sequestering(GO:0043181)
1.8 7.3 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.8 2.4 GO:0048597 B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597) positive regulation of apoptotic DNA fragmentation(GO:1902512)
0.7 4.6 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.7 2.6 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.5 1.6 GO:1902559 3'-phosphoadenosine 5'-phosphosulfate transport(GO:0046963) 3'-phospho-5'-adenylyl sulfate transmembrane transport(GO:1902559)
0.5 1.5 GO:0060620 regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.4 1.3 GO:1990828 response to putrescine(GO:1904585) cellular response to putrescine(GO:1904586) hepatocyte dedifferentiation(GO:1990828)
0.4 2.1 GO:0043335 protein unfolding(GO:0043335)
0.4 1.6 GO:1904481 response to tetrahydrofolate(GO:1904481) cellular response to tetrahydrofolate(GO:1904482)
0.4 1.2 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.4 2.5 GO:1904636 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.3 1.0 GO:0070407 oxidation-dependent protein catabolic process(GO:0070407)
0.3 1.2 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.2 1.7 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.2 0.7 GO:0015680 intracellular copper ion transport(GO:0015680)
0.2 3.3 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.2 1.1 GO:0070829 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.2 1.4 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.2 4.4 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.2 0.7 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
0.2 1.1 GO:0012502 induction of programmed cell death(GO:0012502) positive regulation of apoptotic process in other organism(GO:0044533) positive regulation by symbiont of host programmed cell death(GO:0052042) positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052330) positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction(GO:0052501)
0.2 1.9 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.2 1.0 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.2 0.2 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.2 0.8 GO:0006788 heme oxidation(GO:0006788) negative regulation of mast cell cytokine production(GO:0032764) regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
0.2 0.6 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.2 0.6 GO:0060166 olfactory pit development(GO:0060166)
0.2 0.6 GO:0032903 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.2 0.7 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.2 0.6 GO:0061580 colon epithelial cell migration(GO:0061580)
0.2 0.9 GO:0043321 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.2 2.3 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.2 0.7 GO:1902269 positive regulation of polyamine transmembrane transport(GO:1902269)
0.2 0.7 GO:0042823 pyridoxal phosphate biosynthetic process(GO:0042823)
0.2 1.5 GO:0015808 L-alanine transport(GO:0015808)
0.2 0.7 GO:0086053 AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
0.2 1.1 GO:0034036 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.2 0.8 GO:0046203 spermidine catabolic process(GO:0046203)
0.2 0.6 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.1 1.3 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.1 0.8 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.1 0.5 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.1 1.5 GO:0036506 maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.1 0.4 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.9 GO:0071461 cellular response to redox state(GO:0071461)
0.1 1.0 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.1 0.7 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.1 0.3 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.1 1.7 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.1 0.4 GO:1904845 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.1 1.1 GO:0015889 cobalamin transport(GO:0015889)
0.1 0.3 GO:0019516 lactate oxidation(GO:0019516)
0.1 0.4 GO:0006566 threonine metabolic process(GO:0006566)
0.1 0.4 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.1 0.5 GO:0009608 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609) response to selenium ion(GO:0010269)
0.1 1.4 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 0.6 GO:0070981 L-asparagine biosynthetic process(GO:0070981) L-asparagine metabolic process(GO:0070982)
0.1 0.4 GO:0060535 trachea cartilage morphogenesis(GO:0060535)
0.1 0.9 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.1 0.3 GO:0021775 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.1 0.9 GO:0006489 dolichyl diphosphate biosynthetic process(GO:0006489) dolichyl diphosphate metabolic process(GO:0046465)
0.1 1.3 GO:0006477 protein sulfation(GO:0006477)
0.1 0.6 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
0.1 4.1 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.1 0.6 GO:0019087 transformation of host cell by virus(GO:0019087) renal water absorption(GO:0070295)
0.1 0.5 GO:0043096 purine nucleobase salvage(GO:0043096)
0.1 0.6 GO:1903232 melanosome assembly(GO:1903232)
0.1 0.5 GO:1902164 regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.1 1.6 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.1 0.2 GO:0006043 glucosamine catabolic process(GO:0006043)
0.1 0.2 GO:0002879 positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.1 0.9 GO:0016139 glycoside catabolic process(GO:0016139)
0.1 0.3 GO:0070384 Harderian gland development(GO:0070384)
0.1 0.6 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.1 0.5 GO:0021546 rhombomere development(GO:0021546)
0.1 0.3 GO:0019859 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.1 0.2 GO:0045799 positive regulation of chromatin assembly or disassembly(GO:0045799)
0.1 0.4 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
0.1 0.9 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.1 0.1 GO:0005985 sucrose metabolic process(GO:0005985)
0.1 0.5 GO:0046618 drug export(GO:0046618)
0.1 0.9 GO:0048484 enteric nervous system development(GO:0048484)
0.1 0.5 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.1 0.9 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.1 1.2 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.1 0.5 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.1 0.3 GO:0007099 centriole replication(GO:0007099)
0.1 0.3 GO:0043686 co-translational protein modification(GO:0043686)
0.1 3.2 GO:0009303 rRNA transcription(GO:0009303)
0.1 1.0 GO:0044351 macropinocytosis(GO:0044351)
0.1 0.5 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.1 0.2 GO:1904354 negative regulation of telomere capping(GO:1904354)
0.1 3.0 GO:0030262 apoptotic nuclear changes(GO:0030262)
0.1 0.9 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
0.1 0.3 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.1 0.2 GO:0009227 UDP-glucose catabolic process(GO:0006258) nucleotide-sugar catabolic process(GO:0009227)
0.1 0.1 GO:0002424 T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840)
0.1 0.3 GO:0035509 negative regulation of myosin-light-chain-phosphatase activity(GO:0035509) negative regulation of bicellular tight junction assembly(GO:1903347)
0.1 1.0 GO:0009125 nucleoside monophosphate catabolic process(GO:0009125)
0.1 1.1 GO:0000338 protein deneddylation(GO:0000338)
0.1 0.2 GO:0032053 ciliary basal body organization(GO:0032053) positive regulation of protein localization to cilium(GO:1903566)
0.1 0.2 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.1 0.2 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.1 0.4 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.1 0.2 GO:0002384 hepatic immune response(GO:0002384)
0.1 0.2 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.1 0.5 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.1 1.0 GO:0002115 store-operated calcium entry(GO:0002115)
0.1 0.3 GO:0061113 pancreas morphogenesis(GO:0061113)
0.1 0.3 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.1 1.1 GO:0030207 chondroitin sulfate catabolic process(GO:0030207)
0.0 0.3 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.1 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.0 0.5 GO:0000821 regulation of arginine metabolic process(GO:0000821) basic amino acid transmembrane transport(GO:1990822)
0.0 0.1 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.0 0.3 GO:2001033 negative regulation of double-strand break repair via nonhomologous end joining(GO:2001033)
0.0 0.1 GO:0019240 protein citrullination(GO:0018101) citrulline biosynthetic process(GO:0019240) histone citrullination(GO:0036414)
0.0 0.1 GO:1990167 protein K27-linked deubiquitination(GO:1990167)
0.0 0.7 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.3 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.8 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.6 GO:0035826 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.0 0.1 GO:0032661 regulation of interleukin-18 production(GO:0032661) positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0 0.7 GO:0015886 heme transport(GO:0015886)
0.0 0.2 GO:0006710 androgen catabolic process(GO:0006710)
0.0 0.3 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.5 GO:2000767 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) positive regulation of cytoplasmic translation(GO:2000767)
0.0 0.1 GO:0060279 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.0 0.2 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.0 0.4 GO:1905146 lysosomal protein catabolic process(GO:1905146)
0.0 0.1 GO:1901207 regulation of heart looping(GO:1901207)
0.0 0.3 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.0 0.2 GO:0061143 alveolar primary septum development(GO:0061143)
0.0 0.2 GO:0010693 negative regulation of alkaline phosphatase activity(GO:0010693)
0.0 0.3 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.0 1.3 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.3 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.0 0.2 GO:0015887 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887)
0.0 0.1 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.0 0.1 GO:0060730 regulation of intestinal epithelial structure maintenance(GO:0060730)
0.0 0.5 GO:1900825 regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900825)
0.0 0.2 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.0 0.3 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.1 GO:0006565 L-serine catabolic process(GO:0006565)
0.0 1.1 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.2 GO:1903401 L-lysine transmembrane transport(GO:1903401)
0.0 0.1 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0 0.5 GO:0006265 DNA topological change(GO:0006265)
0.0 2.9 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.2 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.1 GO:0070904 L-ascorbic acid transport(GO:0015882) molecular hydrogen transport(GO:0015993) transepithelial L-ascorbic acid transport(GO:0070904)
0.0 0.3 GO:0097167 circadian regulation of translation(GO:0097167)
0.0 0.9 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.6 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.1 GO:0036090 cleavage furrow ingression(GO:0036090)
0.0 0.8 GO:0007141 male meiosis I(GO:0007141)
0.0 0.2 GO:1904578 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579) response to hypobaric hypoxia(GO:1990910)
0.0 0.5 GO:0046322 negative regulation of fatty acid oxidation(GO:0046322)
0.0 0.0 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.0 0.1 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.0 0.3 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.0 0.5 GO:0035878 nail development(GO:0035878)
0.0 1.6 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.0 0.2 GO:0050893 sensory processing(GO:0050893)
0.0 0.4 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.2 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.0 0.2 GO:0043128 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.0 0.5 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.6 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.8 GO:1901798 positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.0 0.2 GO:0015860 purine nucleoside transmembrane transport(GO:0015860)
0.0 2.7 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.4 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.4 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.1 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 0.5 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.2 GO:0040034 regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.0 0.3 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.0 0.4 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 1.8 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 0.6 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.1 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 1.2 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.1 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.0 0.3 GO:0015866 ADP transport(GO:0015866)
0.0 0.3 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.3 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.1 GO:0072553 terminal button organization(GO:0072553)
0.0 0.2 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.2 GO:0006740 NADPH regeneration(GO:0006740)
0.0 0.6 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.1 GO:1904431 positive regulation of t-circle formation(GO:1904431)
0.0 0.2 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.0 0.8 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.4 GO:0015893 drug transport(GO:0015893)
0.0 0.2 GO:0060056 mammary gland involution(GO:0060056)
0.0 0.9 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.1 GO:1904995 negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995)
0.0 0.9 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 2.0 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.3 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.2 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.4 GO:0034162 toll-like receptor 9 signaling pathway(GO:0034162)
0.0 0.2 GO:0060736 prostate gland growth(GO:0060736)
0.0 0.3 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.1 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.0 0.4 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.2 GO:0010043 response to zinc ion(GO:0010043)
0.0 0.3 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 0.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.3 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
0.0 0.1 GO:1904749 regulation of protein localization to nucleolus(GO:1904749)
0.0 0.1 GO:0010159 specification of organ position(GO:0010159)
0.0 0.3 GO:0010833 telomere maintenance via telomere lengthening(GO:0010833)
0.0 0.2 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.1 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.1 GO:0003363 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.0 0.2 GO:0019532 oxalate transport(GO:0019532)
0.0 0.3 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.3 GO:0007567 parturition(GO:0007567)
0.0 0.2 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.2 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.6 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211)
0.0 0.2 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.1 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0 0.4 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.1 GO:0061053 somite development(GO:0061053)
0.0 0.1 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.2 GO:2000615 regulation of histone H3-K9 acetylation(GO:2000615)
0.0 0.1 GO:0070560 calcium-mediated signaling using extracellular calcium source(GO:0035585) protein secretion by platelet(GO:0070560)
0.0 0.3 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.2 GO:0021860 pyramidal neuron development(GO:0021860)
0.0 0.2 GO:0006970 response to osmotic stress(GO:0006970)
0.0 0.2 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 0.8 GO:0097484 dendrite extension(GO:0097484)
0.0 0.6 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.0 GO:2001187 positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187)
0.0 0.3 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.2 GO:2000394 positive regulation of lamellipodium morphogenesis(GO:2000394)
0.0 0.0 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.0 0.0 GO:0090675 intermicrovillar adhesion(GO:0090675)
0.0 0.1 GO:0051013 microtubule severing(GO:0051013)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.0 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.0 0.0 GO:0050823 peptide stabilization(GO:0050822) peptide antigen stabilization(GO:0050823)
0.0 0.1 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.8 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.5 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.1 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0 0.0 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.0 0.1 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.6 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 0.3 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.0 GO:0046833 positive regulation of RNA export from nucleus(GO:0046833)
0.0 0.1 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.1 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.0 0.2 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.1 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0 0.0 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.0 0.1 GO:0046321 positive regulation of fatty acid oxidation(GO:0046321)
0.0 0.3 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
0.0 0.1 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0 0.3 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 0.1 GO:0002021 response to dietary excess(GO:0002021)
0.0 0.1 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.0 0.1 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999)
0.0 0.1 GO:0031577 spindle checkpoint(GO:0031577)
0.0 0.4 GO:0014047 glutamate secretion(GO:0014047)
0.0 0.3 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.0 0.6 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.3 GO:1904031 positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0 0.1 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.5 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.3 3.1 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.3 1.0 GO:0035101 FACT complex(GO:0035101)
0.2 1.4 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.2 3.0 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.2 1.5 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.2 1.5 GO:0030896 checkpoint clamp complex(GO:0030896)
0.2 1.2 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.1 0.8 GO:0044194 cytolytic granule(GO:0044194)
0.1 1.4 GO:0070552 BRISC complex(GO:0070552)
0.1 0.4 GO:0005588 collagen type V trimer(GO:0005588)
0.1 1.8 GO:0071986 Ragulator complex(GO:0071986)
0.1 1.5 GO:0072379 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1 1.0 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 0.9 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.1 0.7 GO:0089701 U2AF(GO:0089701)
0.1 0.5 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.1 0.2 GO:0030662 coated vesicle membrane(GO:0030662)
0.1 0.6 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.1 7.0 GO:0016235 aggresome(GO:0016235)
0.1 14.7 GO:0043202 lysosomal lumen(GO:0043202)
0.1 1.1 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.1 0.3 GO:0005667 transcription factor complex(GO:0005667)
0.1 0.5 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 1.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 0.2 GO:0030133 transport vesicle(GO:0030133)
0.1 0.5 GO:0001740 Barr body(GO:0001740)
0.1 0.6 GO:0097413 Lewy body(GO:0097413)
0.1 1.2 GO:0030914 STAGA complex(GO:0030914)
0.1 1.1 GO:0042555 MCM complex(GO:0042555)
0.1 0.2 GO:0031085 BLOC-3 complex(GO:0031085)
0.1 0.4 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 0.4 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 1.0 GO:0042405 nuclear inclusion body(GO:0042405)
0.1 5.6 GO:0035578 azurophil granule lumen(GO:0035578)
0.1 0.2 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.1 1.7 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 0.2 GO:0070110 ciliary neurotrophic factor receptor complex(GO:0070110)
0.0 0.2 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 0.5 GO:0072487 MSL complex(GO:0072487)
0.0 0.3 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.4 GO:0005827 polar microtubule(GO:0005827)
0.0 0.3 GO:0097361 CIA complex(GO:0097361)
0.0 0.6 GO:0097487 platelet dense granule membrane(GO:0031088) multivesicular body, internal vesicle(GO:0097487)
0.0 0.6 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.6 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.1 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.7 GO:0005922 connexon complex(GO:0005922)
0.0 0.4 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 1.1 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.3 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.5 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 2.1 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.8 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 5.6 GO:0005795 Golgi stack(GO:0005795)
0.0 0.1 GO:0001534 radial spoke(GO:0001534)
0.0 0.1 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.5 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.6 GO:0031264 death-inducing signaling complex(GO:0031264)
0.0 0.4 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.2 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.2 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.5 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.2 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.5 GO:0000782 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0 0.1 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.4 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.7 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.4 GO:0005901 caveola(GO:0005901)
0.0 0.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 1.3 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.1 GO:0097452 GAIT complex(GO:0097452)
0.0 0.3 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 1.0 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.3 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 1.1 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.2 GO:0005638 lamin filament(GO:0005638)
0.0 0.3 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.3 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.2 GO:0042827 platelet dense granule(GO:0042827)
0.0 0.3 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.3 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 7.4 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.2 GO:0000322 storage vacuole(GO:0000322)
0.0 0.2 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 1.2 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.2 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.0 GO:0010370 perinucleolar chromocenter(GO:0010370)
0.0 0.2 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.3 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.1 GO:0005883 neurofilament(GO:0005883)
0.0 0.6 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.1 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.8 GO:0045171 intercellular bridge(GO:0045171)
0.0 1.2 GO:0005776 autophagosome(GO:0005776)
0.0 0.0 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0 0.0 GO:0045281 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.6 GO:0016592 mediator complex(GO:0016592)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 6.7 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.7 4.4 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.7 2.0 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.5 1.6 GO:0004853 uroporphyrinogen decarboxylase activity(GO:0004853)
0.5 1.6 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.5 2.3 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.4 1.2 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.3 1.4 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.3 1.6 GO:0070905 serine binding(GO:0070905)
0.3 1.0 GO:0070362 mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364)
0.3 3.9 GO:0004630 phospholipase D activity(GO:0004630)
0.3 1.6 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.3 0.8 GO:0034038 deoxyhypusine synthase activity(GO:0034038)
0.2 0.7 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.2 1.1 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.2 1.4 GO:0004793 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.2 5.1 GO:0015929 hexosaminidase activity(GO:0015929)
0.2 0.6 GO:0004458 D-lactate dehydrogenase (cytochrome) activity(GO:0004458) oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor(GO:0016898)
0.2 2.4 GO:0051434 BH3 domain binding(GO:0051434)
0.2 0.6 GO:0048257 3'-flap endonuclease activity(GO:0048257)
0.2 1.3 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.2 2.3 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.2 0.5 GO:0016936 galactoside binding(GO:0016936)
0.2 1.5 GO:0022858 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.2 0.7 GO:0086077 gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
0.2 0.8 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.1 3.2 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 7.0 GO:0005109 frizzled binding(GO:0005109)
0.1 1.7 GO:0004308 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.1 0.8 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.1 0.5 GO:0002060 purine nucleobase binding(GO:0002060)
0.1 0.4 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.1 0.3 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.1 1.1 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.1 0.5 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) aspartic-type endopeptidase inhibitor activity(GO:0019828) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1 0.4 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.1 0.7 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.1 0.7 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.1 0.8 GO:0070513 death domain binding(GO:0070513)
0.1 3.7 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 0.5 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.1 0.3 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.1 0.9 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.1 1.1 GO:0031419 cobalamin binding(GO:0031419)
0.1 0.5 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 0.3 GO:0004560 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.1 0.6 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.1 1.0 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 0.3 GO:0035248 alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248)
0.1 0.6 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.1 0.3 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
0.1 0.5 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.1 0.2 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.1 1.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 0.7 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.1 1.4 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 2.1 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 1.8 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 0.6 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1 0.2 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.1 0.2 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.1 0.3 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.1 1.5 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 0.3 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 0.8 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 0.3 GO:0016402 pristanoyl-CoA oxidase activity(GO:0016402)
0.1 0.2 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 0.6 GO:0019534 toxin transporter activity(GO:0019534)
0.1 0.4 GO:0016453 C-acetyltransferase activity(GO:0016453)
0.1 4.0 GO:0050699 WW domain binding(GO:0050699)
0.1 0.2 GO:0070538 oleic acid binding(GO:0070538)
0.1 0.5 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.1 0.6 GO:1990446 U1 snRNP binding(GO:1990446)
0.1 0.2 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.1 0.9 GO:0003680 AT DNA binding(GO:0003680)
0.1 0.4 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.1 0.5 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.1 0.3 GO:0008384 IkappaB kinase activity(GO:0008384)
0.1 0.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.2 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.1 0.2 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.1 0.2 GO:0004756 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.1 0.2 GO:0016652 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.1 2.2 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 0.5 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.5 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.9 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.3 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.1 GO:0038131 neuregulin receptor activity(GO:0038131)
0.0 0.5 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.3 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.0 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.0 0.8 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.9 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.8 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.3 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.0 0.1 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.0 0.2 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.1 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.2 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.5 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.2 GO:0033612 receptor serine/threonine kinase binding(GO:0033612)
0.0 0.3 GO:0035500 MH2 domain binding(GO:0035500)
0.0 2.5 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.1 GO:0016662 cystathionine beta-synthase activity(GO:0004122) oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) nitrite reductase (NO-forming) activity(GO:0050421) carbon monoxide binding(GO:0070025) nitrite reductase activity(GO:0098809)
0.0 0.1 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.7 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.6 GO:0010181 FMN binding(GO:0010181)
0.0 0.8 GO:0005522 profilin binding(GO:0005522)
0.0 0.6 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.1 GO:0009383 rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383)
0.0 0.2 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.3 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 3.9 GO:0019213 deacetylase activity(GO:0019213)
0.0 0.3 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.4 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.2 GO:0004572 mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity(GO:0004572)
0.0 0.1 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.5 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.2 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.5 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.0 0.2 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.0 0.4 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.8 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.2 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 5.7 GO:0008083 growth factor activity(GO:0008083)
0.0 0.3 GO:0042910 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0 0.1 GO:0005365 myo-inositol transmembrane transporter activity(GO:0005365)
0.0 0.3 GO:0001016 RNA polymerase III regulatory region DNA binding(GO:0001016)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.5 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.1 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.0 0.6 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.3 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.8 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.9 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.2 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.9 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.3 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.3 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.0 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.2 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 1.3 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.3 GO:1903136 cuprous ion binding(GO:1903136)
0.0 0.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.6 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.0 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.1 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.2 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.1 GO:0031626 beta-endorphin binding(GO:0031626)
0.0 0.2 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.3 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.0 0.4 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.7 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.1 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 1.1 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.1 GO:0004348 glucosylceramidase activity(GO:0004348)
0.0 0.1 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.5 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.5 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.3 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.7 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 1.3 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 0.2 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.6 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.0 0.0 GO:0016635 succinate dehydrogenase (ubiquinone) activity(GO:0008177) oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0 0.0 GO:0004961 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.0 0.5 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.1 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 0.1 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.2 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.2 GO:0001164 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 2.1 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.2 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.1 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.3 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.1 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.4 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.2 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.7 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.4 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.0 GO:0070051 fibrinogen binding(GO:0070051)
0.0 0.2 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.1 GO:0004645 phosphorylase activity(GO:0004645)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 7.0 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.1 2.1 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 3.0 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 6.1 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 2.8 ST GA12 PATHWAY G alpha 12 Pathway
0.0 1.4 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.3 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 2.4 PID ATR PATHWAY ATR signaling pathway
0.0 0.5 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 1.1 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.9 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 2.3 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 2.4 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.2 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 0.2 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.2 ST STAT3 PATHWAY STAT3 Pathway
0.0 1.1 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.4 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.6 PID IFNG PATHWAY IFN-gamma pathway
0.0 1.2 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.5 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.6 NABA COLLAGENS Genes encoding collagen proteins
0.0 1.0 WNT SIGNALING Genes related to Wnt-mediated signal transduction

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 7.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 2.4 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 2.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 3.8 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.1 1.0 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 0.1 REACTOME SHC RELATED EVENTS Genes involved in SHC-related events
0.1 1.0 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 1.2 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 1.6 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.6 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.6 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 1.1 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 1.2 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.9 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 1.2 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.5 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 1.6 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.6 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.3 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 1.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.6 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.8 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.5 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 1.9 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.9 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.9 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 1.9 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.5 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 1.6 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.4 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.3 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.9 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 2.3 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.2 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 1.2 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.4 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.5 REACTOME EARLY PHASE OF HIV LIFE CYCLE Genes involved in Early Phase of HIV Life Cycle
0.0 1.0 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.4 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.3 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 1.7 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.3 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.1 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 2.8 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 0.6 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 1.1 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.1 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.2 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 0.5 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.5 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.7 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.9 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.1 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 1.5 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.6 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.1 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.5 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.0 0.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.1 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.2 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism