ISMARA results: TBP

Project

A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

Navigation

Downloads

Results for TBP

Z-value: 3.24

Motif logo

Transcription factors associated with TBP

Gene Symbol	Gene ID	Gene Info
TBP Ensembl NCBI GeneCards UniProt	ENSG00000112592.8	TATA-box binding protein

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
TBP	hg19_v2_chr6_+_170863672_170863698	-0.41	5.9e-01	Click!

Activity profile of TBP motif

Sorted Z-values of TBP motif

Top targets:

Search:

Show entries

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr1_-_149785236 Show fit	2.96	ENST00000331491.1	HIST2H3D Ensembl NCBI GeneCards UniProt Show fit	histone cluster 2, H3d
chr6_+_26156551 Show fit	2.75	ENST00000304218.3	HIST1H1E Ensembl NCBI GeneCards UniProt Show fit	histone cluster 1, H1e
chr6_-_26235206 Show fit	2.70	ENST00000244534.5	HIST1H1D Ensembl NCBI GeneCards UniProt Show fit	histone cluster 1, H1d
chr6_-_26032288 Show fit	2.23	ENST00000244661.2	HIST1H3B Ensembl NCBI GeneCards UniProt Show fit	histone cluster 1, H3b
chr6_+_27114861 Show fit	2.19	ENST00000377459.1	HIST1H2AH Ensembl NCBI GeneCards UniProt Show fit	histone cluster 1, H2ah
chr5_+_53686658 Show fit	2.15	ENST00000512618.1	LINC01033 Ensembl NCBI GeneCards UniProt Show fit	long intergenic non-protein coding RNA 1033
chr6_+_26104104 Show fit	2.06	ENST00000377803.2	HIST1H4C Ensembl NCBI GeneCards UniProt Show fit	histone cluster 1, H4c
chr6_-_26189304 Show fit	1.98	ENST00000340756.2	HIST1H4D Ensembl NCBI GeneCards UniProt Show fit	histone cluster 1, H4d
chr6_-_26033796 Show fit	1.96	ENST00000259791.2	HIST1H2AB Ensembl NCBI GeneCards UniProt Show fit	histone cluster 1, H2ab
chr6_-_27835357 Show fit	1.88	ENST00000331442.3	HIST1H1B Ensembl NCBI GeneCards UniProt Show fit	histone cluster 1, H1b

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of TBP

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	5.4	GO:0098532	histone H3-K27 trimethylation(GO:0098532)
0.0	5.4	GO:0006342	chromatin silencing(GO:0006342)
0.4	3.9	GO:0002227	innate immune response in mucosa(GO:0002227)
0.4	3.1	GO:1902527	positive regulation of protein monoubiquitination(GO:1902527)
0.1	2.2	GO:0043587	tongue morphogenesis(GO:0043587)
0.0	2.2	GO:0006334	nucleosome assembly(GO:0006334)
0.2	1.9	GO:0071169	establishment of protein localization to chromatin(GO:0071169)
0.0	1.7	GO:0050716	positive regulation of interleukin-1 secretion(GO:0050716)
0.5	1.5	GO:0033634	positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.3	1.4	GO:0002725	negative regulation of T cell cytokine production(GO:0002725)

Showing 1 to 10 of 119 entries

Gene overrepresentation in cellular_component category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	14.8	GO:0000786	nucleosome(GO:0000786)
0.1	4.2	GO:0045095	keratin filament(GO:0045095)
0.3	3.8	GO:0000788	nuclear nucleosome(GO:0000788)
0.1	3.5	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
0.1	2.4	GO:0071682	endocytic vesicle lumen(GO:0071682)
0.0	2.1	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.0	1.6	GO:0005680	anaphase-promoting complex(GO:0005680)
0.1	1.5	GO:0097225	sperm midpiece(GO:0097225)
0.0	1.4	GO:0034707	chloride channel complex(GO:0034707)
0.0	1.2	GO:0005881	cytoplasmic microtubule(GO:0005881)

Showing 1 to 10 of 51 entries

Gene overrepresentation in molecular_function category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	7.8	GO:0046982	protein heterodimerization activity(GO:0046982)
0.0	3.8	GO:0031490	chromatin DNA binding(GO:0031490)
0.1	3.1	GO:0042056	chemoattractant activity(GO:0042056)
0.5	2.8	GO:0032558	adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.3	2.0	GO:0005132	type I interferon receptor binding(GO:0005132)
0.2	1.5	GO:0031730	CCR5 chemokine receptor binding(GO:0031730)
0.1	1.4	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.1	1.4	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.1	1.4	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0	1.2	GO:0001530	lipopolysaccharide binding(GO:0001530)

Showing 1 to 10 of 89 entries

Gene overrepresentation in C2:CP category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.2	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.0	2.0	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	1.7	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	1.6	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.1	1.4	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.0	1.3	ST P38 MAPK PATHWAY	p38 MAPK Pathway
0.0	1.3	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0	1.2	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.0	1.1	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.0	0.9	PID RHOA PATHWAY	RhoA signaling pathway

Showing 1 to 10 of 18 entries

Gene overrepresentation in C2:CP:REACTOME category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	28.3	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.4	7.3	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.1	2.2	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.1	2.0	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.1	2.0	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.1	1.9	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.1	1.7	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.2	1.5	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.0	1.4	REACTOME PHOSPHORYLATION OF THE APC C	Genes involved in Phosphorylation of the APC/C
0.0	1.4	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane

Showing 1 to 10 of 27 entries

Results for TBP

Z-value: 3.24

Motif logo

Transcription factors associated with TBP

Activity-expression correlation:

Activity profile of TBP motif

Sorted Z-values of TBP motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of TBP

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: