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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for TBX20

Z-value: 0.83

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Transcription factors associated with TBX20

Gene Symbol Gene ID Gene Info
TBX20
ENSG00000164532.10 T-box transcription factor 20

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TBX20hg19_v2_chr7_-_35293740_352937580.722.8e-01Click!

Activity profile of TBX20 motif

Sorted Z-values of TBX20 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_57662527 2.41 ENST00000563374.1
ENST00000568234.1
ENST00000565770.1
ENST00000564338.1
ENST00000566164.1
GPR56
G protein-coupled receptor 56
chr16_+_57662596 1.97 ENST00000567397.1
ENST00000568979.1
GPR56
G protein-coupled receptor 56
chr16_+_57662419 0.94 ENST00000388812.4
ENST00000538815.1
ENST00000456916.1
ENST00000567154.1
ENST00000388813.5
ENST00000562558.1
ENST00000566271.2
GPR56
G protein-coupled receptor 56
chr2_+_64068116 0.67 ENST00000480679.1
UGP2
UDP-glucose pyrophosphorylase 2
chr3_-_50396978 0.37 ENST00000266025.3
TMEM115
transmembrane protein 115
chr14_+_77228532 0.29 ENST00000167106.4
ENST00000554237.1
VASH1
vasohibin 1
chr2_-_219134343 0.29 ENST00000447885.1
ENST00000420660.1
AAMP
angio-associated, migratory cell protein
chr19_+_46171464 0.26 ENST00000590918.1
ENST00000263281.3
ENST00000304207.8
GIPR
gastric inhibitory polypeptide receptor
chr12_-_56123444 0.23 ENST00000546457.1
ENST00000549117.1
CD63
CD63 molecule
chr19_+_35810164 0.23 ENST00000598537.1
CD22
CD22 molecule
chr1_-_154909329 0.23 ENST00000368467.3
PMVK
phosphomevalonate kinase
chr2_+_176972000 0.23 ENST00000249504.5
HOXD11
homeobox D11
chrX_+_67913471 0.20 ENST00000374597.3
STARD8
StAR-related lipid transfer (START) domain containing 8
chr8_+_27182862 0.17 ENST00000521164.1
ENST00000346049.5
PTK2B
protein tyrosine kinase 2 beta
chr6_-_136788001 0.14 ENST00000544465.1
MAP7
microtubule-associated protein 7
chr7_-_33140498 0.12 ENST00000448915.1
RP9
retinitis pigmentosa 9 (autosomal dominant)
chr1_+_147013182 0.10 ENST00000234739.3
BCL9
B-cell CLL/lymphoma 9
chr19_+_17579556 0.10 ENST00000442725.1
SLC27A1
solute carrier family 27 (fatty acid transporter), member 1
chr15_-_74504597 0.10 ENST00000416286.3
STRA6
stimulated by retinoic acid 6
chr15_-_74504560 0.09 ENST00000449139.2
STRA6
stimulated by retinoic acid 6
chr5_+_135394840 0.09 ENST00000503087.1
TGFBI
transforming growth factor, beta-induced, 68kDa
chr10_-_56561022 0.08 ENST00000373965.2
ENST00000414778.1
ENST00000395438.1
ENST00000409834.1
ENST00000395445.1
ENST00000395446.1
ENST00000395442.1
ENST00000395440.1
ENST00000395432.2
ENST00000361849.3
ENST00000395433.1
ENST00000320301.6
ENST00000395430.1
ENST00000437009.1
PCDH15
protocadherin-related 15
chr8_+_27183033 0.08 ENST00000420218.2
PTK2B
protein tyrosine kinase 2 beta
chr19_+_44331555 0.08 ENST00000590950.1
ZNF283
zinc finger protein 283
chr20_+_44509857 0.07 ENST00000372523.1
ENST00000372520.1
ZSWIM1
zinc finger, SWIM-type containing 1
chr7_-_139763521 0.07 ENST00000263549.3
PARP12
poly (ADP-ribose) polymerase family, member 12
chr19_-_10213335 0.07 ENST00000592641.1
ENST00000253109.4
ANGPTL6
angiopoietin-like 6
chr12_-_23737534 0.07 ENST00000396007.2
SOX5
SRY (sex determining region Y)-box 5
chr1_-_11865982 0.06 ENST00000418034.1
MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr3_-_183273477 0.06 ENST00000341319.3
KLHL6
kelch-like family member 6
chr5_+_133861339 0.05 ENST00000282605.4
ENST00000361895.2
ENST00000402835.1
PHF15
jade family PHD finger 2
chr9_-_72287191 0.05 ENST00000265381.4
APBA1
amyloid beta (A4) precursor protein-binding, family A, member 1
chr7_+_114055052 0.05 ENST00000462331.1
ENST00000408937.3
ENST00000403559.4
ENST00000350908.4
ENST00000393498.2
ENST00000393495.3
ENST00000378237.3
ENST00000393489.3
FOXP2
forkhead box P2
chr15_-_74421477 0.04 ENST00000514871.1
RP11-247C2.2
HCG2004779; Uncharacterized protein
chr19_-_9325542 0.04 ENST00000308682.2
OR7D4
olfactory receptor, family 7, subfamily D, member 4
chr19_+_44331493 0.04 ENST00000588797.1
ZNF283
zinc finger protein 283
chr16_+_31044812 0.04 ENST00000313843.3
STX4
syntaxin 4
chr6_-_107077347 0.03 ENST00000369063.3
ENST00000539449.1
RTN4IP1
reticulon 4 interacting protein 1
chr11_-_17410629 0.03 ENST00000526912.1
KCNJ11
potassium inwardly-rectifying channel, subfamily J, member 11
chr2_-_219134822 0.02 ENST00000444053.1
ENST00000248450.4
AAMP
angio-associated, migratory cell protein
chr3_-_139396801 0.02 ENST00000413939.2
ENST00000339837.5
ENST00000512391.1
NMNAT3
nicotinamide nucleotide adenylyltransferase 3
chr22_-_46283597 0.01 ENST00000451118.1
WI2-85898F10.1
WI2-85898F10.1
chr22_+_41956767 0.01 ENST00000306149.7
CSDC2
cold shock domain containing C2, RNA binding
chr3_+_40428647 0.01 ENST00000301825.3
ENST00000439533.1
ENST00000456402.1
ENTPD3
ectonucleoside triphosphate diphosphohydrolase 3
chr7_+_30185496 0.01 ENST00000455738.1
C7orf41
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr2_-_207630033 0.00 ENST00000449792.1
MDH1B
malate dehydrogenase 1B, NAD (soluble)
chr1_+_87797351 0.00 ENST00000370542.1
LMO4
LIM domain only 4
chr15_+_76016293 0.00 ENST00000332145.2
ODF3L1
outer dense fiber of sperm tails 3-like 1

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX20

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 0.3 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.1 0.5 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.0 0.3 GO:2000538 regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.0 0.1 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.0 0.2 GO:0061143 alveolar primary septum development(GO:0061143)
0.0 0.2 GO:2000680 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.0 0.0 GO:0043311 regulation of eosinophil degranulation(GO:0043309) positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.0 0.3 GO:0002029 desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401)
0.0 0.0 GO:0098582 innate vocalization behavior(GO:0098582)
0.0 0.1 GO:0070829 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.2 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.0 0.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.1 GO:0005785 signal recognition particle receptor complex(GO:0005785)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0003983 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.0 0.3 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.1 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME GLUCURONIDATION Genes involved in Glucuronidation