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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for TBX4

Z-value: 0.89

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Transcription factors associated with TBX4

Gene Symbol Gene ID Gene Info
TBX4
ENSG00000121075.5 T-box transcription factor 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TBX4hg19_v2_chr17_+_59529743_59529798-0.703.0e-01Click!

Activity profile of TBX4 motif

Sorted Z-values of TBX4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_29033682 0.61 ENST00000379579.4
ENST00000334056.5
ENST00000449210.1
SPDYA
speedy/RINGO cell cycle regulator family member A
chr7_+_107220899 0.42 ENST00000379117.2
ENST00000473124.1
BCAP29
B-cell receptor-associated protein 29
chr2_-_177684007 0.41 ENST00000451851.1
AC092162.1
AC092162.1
chr8_-_99954788 0.39 ENST00000523601.1
STK3
serine/threonine kinase 3
chr10_+_94833642 0.37 ENST00000224356.4
ENST00000394139.1
CYP26A1
cytochrome P450, family 26, subfamily A, polypeptide 1
chr9_+_40028620 0.36 ENST00000426179.1
AL353791.1
AL353791.1
chr3_+_167453493 0.33 ENST00000295777.5
ENST00000472747.2
SERPINI1
serpin peptidase inhibitor, clade I (neuroserpin), member 1
chr5_+_74807581 0.32 ENST00000241436.4
ENST00000352007.5
POLK
polymerase (DNA directed) kappa
chr8_-_123793048 0.31 ENST00000607710.1
RP11-44N11.2
RP11-44N11.2
chr11_+_111749650 0.31 ENST00000528125.1
C11orf1
chromosome 11 open reading frame 1
chr21_+_30502806 0.30 ENST00000399928.1
ENST00000399926.1
MAP3K7CL
MAP3K7 C-terminal like
chr5_+_74807886 0.29 ENST00000514296.1
POLK
polymerase (DNA directed) kappa
chr5_-_114515734 0.29 ENST00000514154.1
ENST00000282369.3
TRIM36
tripartite motif containing 36
chr11_+_111750206 0.28 ENST00000530214.1
ENST00000530799.1
C11orf1
chromosome 11 open reading frame 1
chr2_+_62933001 0.27 ENST00000263991.5
ENST00000354487.3
EHBP1
EH domain binding protein 1
chr12_+_104324112 0.26 ENST00000299767.5
HSP90B1
heat shock protein 90kDa beta (Grp94), member 1
chr14_+_53196872 0.26 ENST00000442123.2
ENST00000354586.4
STYX
serine/threonine/tyrosine interacting protein
chr11_+_86511549 0.25 ENST00000533902.2
PRSS23
protease, serine, 23
chr2_-_85895295 0.24 ENST00000428225.1
ENST00000519937.2
SFTPB
surfactant protein B
chr6_-_19804973 0.24 ENST00000457670.1
ENST00000607810.1
ENST00000606628.1
RP4-625H18.2
RP4-625H18.2
chr15_+_41913690 0.24 ENST00000563576.1
MGA
MGA, MAX dimerization protein
chr10_-_16563870 0.24 ENST00000298943.3
C1QL3
complement component 1, q subcomponent-like 3
chr12_+_57854274 0.23 ENST00000528432.1
GLI1
GLI family zinc finger 1
chr4_+_57371509 0.23 ENST00000360096.2
ARL9
ADP-ribosylation factor-like 9
chrX_+_16804544 0.23 ENST00000380122.5
ENST00000398155.4
TXLNG
taxilin gamma
chr5_-_34043310 0.22 ENST00000231338.7
C1QTNF3
C1q and tumor necrosis factor related protein 3
chr2_-_157189180 0.22 ENST00000539077.1
ENST00000424077.1
ENST00000426264.1
ENST00000339562.4
ENST00000421709.1
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr11_-_85779971 0.22 ENST00000393346.3
PICALM
phosphatidylinositol binding clathrin assembly protein
chr5_+_32712363 0.22 ENST00000507141.1
NPR3
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
chr7_+_107220660 0.22 ENST00000465919.1
ENST00000445771.2
ENST00000479917.1
ENST00000421217.1
ENST00000457837.1
BCAP29
B-cell receptor-associated protein 29
chr2_-_175869936 0.20 ENST00000409900.3
CHN1
chimerin 1
chr2_+_61108650 0.20 ENST00000295025.8
REL
v-rel avian reticuloendotheliosis viral oncogene homolog
chr11_-_85430204 0.20 ENST00000389958.3
ENST00000527794.1
SYTL2
synaptotagmin-like 2
chr11_+_111749942 0.20 ENST00000260276.3
C11orf1
chromosome 11 open reading frame 1
chr8_-_95907423 0.20 ENST00000396133.3
ENST00000308108.4
CCNE2
cyclin E2
chr11_-_85430088 0.20 ENST00000533057.1
ENST00000533892.1
SYTL2
synaptotagmin-like 2
chr13_-_52027134 0.19 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
INTS6
integrator complex subunit 6
chrX_+_46772065 0.19 ENST00000455411.1
PHF16
jade family PHD finger 3
chr3_+_142315294 0.19 ENST00000464320.1
PLS1
plastin 1
chr7_-_28220354 0.19 ENST00000283928.5
JAZF1
JAZF zinc finger 1
chr2_+_61108771 0.19 ENST00000394479.3
REL
v-rel avian reticuloendotheliosis viral oncogene homolog
chr5_-_74807418 0.19 ENST00000405807.4
ENST00000261415.7
COL4A3BP
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
chr17_+_79031415 0.18 ENST00000572073.1
ENST00000573677.1
BAIAP2
BAI1-associated protein 2
chr2_+_103089756 0.18 ENST00000295269.4
SLC9A4
solute carrier family 9, subfamily A (NHE4, cation proton antiporter 4), member 4
chr1_+_35734616 0.17 ENST00000441447.1
ZMYM4
zinc finger, MYM-type 4
chr2_-_37458749 0.17 ENST00000234170.5
CEBPZ
CCAAT/enhancer binding protein (C/EBP), zeta
chr1_+_26737292 0.16 ENST00000254231.4
LIN28A
lin-28 homolog A (C. elegans)
chr14_-_45603657 0.16 ENST00000396062.3
FKBP3
FK506 binding protein 3, 25kDa
chr1_+_26737253 0.16 ENST00000326279.6
LIN28A
lin-28 homolog A (C. elegans)
chr15_+_36994210 0.16 ENST00000562489.1
C15orf41
chromosome 15 open reading frame 41
chr7_-_123673471 0.16 ENST00000455783.1
TMEM229A
transmembrane protein 229A
chr14_+_21467414 0.16 ENST00000554422.1
ENST00000298681.4
SLC39A2
solute carrier family 39 (zinc transporter), member 2
chr10_+_31608054 0.15 ENST00000320985.10
ENST00000361642.5
ENST00000560721.2
ENST00000558440.1
ENST00000424869.1
ENST00000542815.3
ZEB1
zinc finger E-box binding homeobox 1
chr11_+_18343800 0.15 ENST00000453096.2
GTF2H1
general transcription factor IIH, polypeptide 1, 62kDa
chr3_-_93747425 0.15 ENST00000315099.2
STX19
syntaxin 19
chr11_+_114271251 0.15 ENST00000375490.5
RBM7
RNA binding motif protein 7
chr6_+_79577189 0.15 ENST00000369940.2
IRAK1BP1
interleukin-1 receptor-associated kinase 1 binding protein 1
chr16_+_67596310 0.15 ENST00000264010.4
ENST00000401394.1
CTCF
CCCTC-binding factor (zinc finger protein)
chr5_+_60241020 0.15 ENST00000511107.1
ENST00000502658.1
NDUFAF2
NADH dehydrogenase (ubiquinone) complex I, assembly factor 2
chr2_-_175870085 0.15 ENST00000409156.3
CHN1
chimerin 1
chr17_-_8066843 0.14 ENST00000404970.3
VAMP2
vesicle-associated membrane protein 2 (synaptobrevin 2)
chr11_-_7847519 0.14 ENST00000328375.1
OR5P3
olfactory receptor, family 5, subfamily P, member 3
chr3_+_142315225 0.14 ENST00000457734.2
ENST00000483373.1
ENST00000475296.1
ENST00000495744.1
ENST00000476044.1
ENST00000461644.1
PLS1
plastin 1
chr11_+_18344106 0.14 ENST00000534641.1
ENST00000525831.1
ENST00000265963.4
GTF2H1
general transcription factor IIH, polypeptide 1, 62kDa
chrX_-_133930285 0.14 ENST00000486347.1
ENST00000343004.5
FAM122B
family with sequence similarity 122B
chr9_-_74979420 0.14 ENST00000343431.2
ENST00000376956.3
ZFAND5
zinc finger, AN1-type domain 5
chr7_-_105319536 0.13 ENST00000477775.1
ATXN7L1
ataxin 7-like 1
chr14_+_90864504 0.13 ENST00000544280.2
CALM1
calmodulin 1 (phosphorylase kinase, delta)
chr7_-_27142290 0.13 ENST00000222718.5
HOXA2
homeobox A2
chr5_+_68788594 0.13 ENST00000396442.2
ENST00000380766.2
OCLN
occludin
chr11_+_122709200 0.13 ENST00000227348.4
CRTAM
cytotoxic and regulatory T cell molecule
chr5_+_113697983 0.13 ENST00000264773.3
KCNN2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr21_+_30503282 0.13 ENST00000399925.1
MAP3K7CL
MAP3K7 C-terminal like
chr1_+_145507587 0.12 ENST00000330165.8
ENST00000369307.3
RBM8A
RNA binding motif protein 8A
chr11_-_65629497 0.12 ENST00000532134.1
CFL1
cofilin 1 (non-muscle)
chr9_+_127023704 0.12 ENST00000373596.1
ENST00000425237.1
NEK6
NIMA-related kinase 6
chr2_-_219925189 0.12 ENST00000295731.6
IHH
indian hedgehog
chr5_+_60240943 0.12 ENST00000296597.5
NDUFAF2
NADH dehydrogenase (ubiquinone) complex I, assembly factor 2
chr17_+_30771279 0.12 ENST00000261712.3
ENST00000578213.1
ENST00000457654.2
ENST00000579451.1
PSMD11
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chrX_+_123095546 0.12 ENST00000371157.3
ENST00000371145.3
ENST00000371144.3
STAG2
stromal antigen 2
chr3_+_107364769 0.12 ENST00000449271.1
ENST00000425868.1
ENST00000449213.1
BBX
bobby sox homolog (Drosophila)
chr3_-_49459865 0.12 ENST00000427987.1
AMT
aminomethyltransferase
chr3_+_107364683 0.12 ENST00000413213.1
BBX
bobby sox homolog (Drosophila)
chr11_+_114270752 0.11 ENST00000540163.1
RBM7
RNA binding motif protein 7
chr7_+_143013198 0.11 ENST00000343257.2
CLCN1
chloride channel, voltage-sensitive 1
chr11_-_62689046 0.11 ENST00000306960.3
ENST00000543973.1
CHRM1
cholinergic receptor, muscarinic 1
chr1_+_16062820 0.11 ENST00000294454.5
SLC25A34
solute carrier family 25, member 34
chr3_+_63805017 0.11 ENST00000295896.8
C3orf49
chromosome 3 open reading frame 49
chr6_-_19804877 0.11 ENST00000447250.1
RP4-625H18.2
RP4-625H18.2
chr9_-_75567962 0.10 ENST00000297785.3
ENST00000376939.1
ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr2_+_219081817 0.10 ENST00000315717.5
ENST00000420104.1
ENST00000295685.10
ARPC2
actin related protein 2/3 complex, subunit 2, 34kDa
chr11_-_85430163 0.10 ENST00000529581.1
ENST00000533577.1
SYTL2
synaptotagmin-like 2
chr2_+_43864387 0.10 ENST00000282406.4
PLEKHH2
pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
chr5_-_78809950 0.10 ENST00000334082.6
HOMER1
homer homolog 1 (Drosophila)
chrX_-_19689106 0.10 ENST00000379716.1
SH3KBP1
SH3-domain kinase binding protein 1
chr2_+_62932779 0.09 ENST00000427809.1
ENST00000405482.1
ENST00000431489.1
EHBP1
EH domain binding protein 1
chr3_+_52422899 0.09 ENST00000480649.1
DNAH1
dynein, axonemal, heavy chain 1
chr5_-_60240858 0.09 ENST00000426742.2
ENST00000265038.5
ENST00000543101.1
ENST00000439176.1
ERCC8
excision repair cross-complementing rodent repair deficiency, complementation group 8
chr7_-_76255444 0.09 ENST00000454397.1
POMZP3
POM121 and ZP3 fusion
chr1_+_95582881 0.09 ENST00000370203.4
ENST00000456991.1
TMEM56
transmembrane protein 56
chr10_-_98945264 0.08 ENST00000314867.5
SLIT1
slit homolog 1 (Drosophila)
chr2_-_61697862 0.08 ENST00000398571.2
USP34
ubiquitin specific peptidase 34
chr13_-_46543805 0.08 ENST00000378921.2
ZC3H13
zinc finger CCCH-type containing 13
chr11_+_73358690 0.08 ENST00000545798.1
ENST00000539157.1
ENST00000546251.1
ENST00000535582.1
ENST00000538227.1
ENST00000543524.1
PLEKHB1
pleckstrin homology domain containing, family B (evectins) member 1
chr13_-_36429763 0.08 ENST00000379893.1
DCLK1
doublecortin-like kinase 1
chr6_+_30295036 0.08 ENST00000376659.5
ENST00000428555.1
TRIM39
tripartite motif containing 39
chr2_+_37458904 0.08 ENST00000416653.1
NDUFAF7
NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
chr2_+_37458928 0.08 ENST00000439218.1
ENST00000432075.1
NDUFAF7
NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
chr10_-_75226166 0.08 ENST00000544628.1
PPP3CB
protein phosphatase 3, catalytic subunit, beta isozyme
chr9_+_140032842 0.08 ENST00000371561.3
ENST00000315048.3
GRIN1
glutamate receptor, ionotropic, N-methyl D-aspartate 1
chr2_+_202937972 0.08 ENST00000541917.1
ENST00000295844.3
AC079354.1
uncharacterized protein KIAA2012
chr11_+_17568920 0.08 ENST00000399391.2
OTOG
otogelin
chr4_+_140222609 0.07 ENST00000296543.5
ENST00000398947.1
NAA15
N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chr11_-_34535332 0.07 ENST00000257832.2
ENST00000429939.2
ELF5
E74-like factor 5 (ets domain transcription factor)
chr5_+_56469843 0.07 ENST00000514387.2
GPBP1
GC-rich promoter binding protein 1
chr3_-_49459878 0.07 ENST00000546031.1
ENST00000458307.2
ENST00000430521.1
AMT
aminomethyltransferase
chr2_+_154728426 0.07 ENST00000392825.3
ENST00000434213.1
GALNT13
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13 (GalNAc-T13)
chr2_+_219472488 0.07 ENST00000450993.2
PLCD4
phospholipase C, delta 4
chr6_+_7541808 0.07 ENST00000379802.3
DSP
desmoplakin
chr5_-_172756506 0.06 ENST00000265087.4
STC2
stanniocalcin 2
chr5_+_56469939 0.06 ENST00000506184.2
GPBP1
GC-rich promoter binding protein 1
chrX_+_70443050 0.06 ENST00000361726.6
GJB1
gap junction protein, beta 1, 32kDa
chr4_-_186456652 0.06 ENST00000284767.5
ENST00000284770.5
PDLIM3
PDZ and LIM domain 3
chr14_+_78870030 0.06 ENST00000553631.1
ENST00000554719.1
NRXN3
neurexin 3
chrX_+_46771711 0.06 ENST00000424392.1
ENST00000397189.1
PHF16
jade family PHD finger 3
chr9_-_117692697 0.06 ENST00000223795.2
TNFSF8
tumor necrosis factor (ligand) superfamily, member 8
chr1_-_226076843 0.06 ENST00000272134.5
LEFTY1
left-right determination factor 1
chr2_+_172864490 0.06 ENST00000315796.4
METAP1D
methionyl aminopeptidase type 1D (mitochondrial)
chr10_+_7860460 0.06 ENST00000344293.5
TAF3
TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa
chr9_+_71986182 0.06 ENST00000303068.7
FAM189A2
family with sequence similarity 189, member A2
chr11_-_128737163 0.05 ENST00000324003.3
ENST00000392665.2
KCNJ1
potassium inwardly-rectifying channel, subfamily J, member 1
chr6_+_39760129 0.05 ENST00000274867.4
DAAM2
dishevelled associated activator of morphogenesis 2
chr14_-_65569244 0.05 ENST00000557277.1
ENST00000556892.1
MAX
MYC associated factor X
chr14_+_75746781 0.05 ENST00000555347.1
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr8_+_95907993 0.05 ENST00000523378.1
NDUFAF6
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chr7_+_133261209 0.05 ENST00000545148.1
EXOC4
exocyst complex component 4
chr16_+_2588012 0.05 ENST00000354836.5
ENST00000389224.3
PDPK1
3-phosphoinositide dependent protein kinase-1
chr4_-_186456766 0.05 ENST00000284771.6
PDLIM3
PDZ and LIM domain 3
chr3_-_197024394 0.05 ENST00000434148.1
ENST00000412364.2
ENST00000436682.1
ENST00000456699.2
ENST00000392380.2
DLG1
discs, large homolog 1 (Drosophila)
chr1_-_111148241 0.05 ENST00000440270.1
KCNA2
potassium voltage-gated channel, shaker-related subfamily, member 2
chr11_-_34535297 0.05 ENST00000532417.1
ELF5
E74-like factor 5 (ets domain transcription factor)
chr2_+_37458776 0.04 ENST00000002125.4
ENST00000336237.6
ENST00000431821.1
NDUFAF7
NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
chr2_-_61108449 0.04 ENST00000439412.1
ENST00000452343.1
AC010733.4
AC010733.4
chr11_+_73358594 0.04 ENST00000227214.6
ENST00000398494.4
ENST00000543085.1
PLEKHB1
pleckstrin homology domain containing, family B (evectins) member 1
chr11_-_128737259 0.04 ENST00000440599.2
ENST00000392666.1
ENST00000324036.3
KCNJ1
potassium inwardly-rectifying channel, subfamily J, member 1
chr2_-_160473114 0.04 ENST00000392783.2
BAZ2B
bromodomain adjacent to zinc finger domain, 2B
chr15_-_83474806 0.04 ENST00000541889.1
ENST00000334574.8
ENST00000561368.1
FSD2
fibronectin type III and SPRY domain containing 2
chr5_+_56469775 0.04 ENST00000424459.3
GPBP1
GC-rich promoter binding protein 1
chr7_-_150675372 0.04 ENST00000262186.5
KCNH2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr1_+_114471809 0.04 ENST00000426820.2
HIPK1
homeodomain interacting protein kinase 1
chr15_-_38852251 0.04 ENST00000558432.1
RASGRP1
RAS guanyl releasing protein 1 (calcium and DAG-regulated)
chr11_-_7818520 0.04 ENST00000329434.2
OR5P2
olfactory receptor, family 5, subfamily P, member 2
chr15_-_58357932 0.04 ENST00000347587.3
ALDH1A2
aldehyde dehydrogenase 1 family, member A2
chr11_-_18343669 0.04 ENST00000396253.3
ENST00000349215.3
ENST00000438420.2
HPS5
Hermansky-Pudlak syndrome 5
chr1_+_114471972 0.03 ENST00000369559.4
ENST00000369554.2
HIPK1
homeodomain interacting protein kinase 1
chr11_+_4116054 0.03 ENST00000423050.2
RRM1
ribonucleotide reductase M1
chr12_-_90024360 0.03 ENST00000393164.2
ATP2B1
ATPase, Ca++ transporting, plasma membrane 1
chr20_+_11898507 0.03 ENST00000378226.2
BTBD3
BTB (POZ) domain containing 3
chr16_+_2587965 0.03 ENST00000342085.4
ENST00000566659.1
PDPK1
3-phosphoinositide dependent protein kinase-1
chr1_+_114472481 0.03 ENST00000369555.2
HIPK1
homeodomain interacting protein kinase 1
chr11_-_85430356 0.03 ENST00000526999.1
SYTL2
synaptotagmin-like 2
chr4_-_114682597 0.03 ENST00000394524.3
CAMK2D
calcium/calmodulin-dependent protein kinase II delta
chr7_+_27282319 0.03 ENST00000222761.3
EVX1
even-skipped homeobox 1
chr4_-_146859787 0.03 ENST00000508784.1
ZNF827
zinc finger protein 827
chr7_-_71801980 0.03 ENST00000329008.5
CALN1
calneuron 1
chrX_+_46771848 0.02 ENST00000218343.4
PHF16
jade family PHD finger 3
chrX_+_123095890 0.02 ENST00000435215.1
STAG2
stromal antigen 2
chr1_+_206680879 0.02 ENST00000355294.4
ENST00000367117.3
RASSF5
Ras association (RalGDS/AF-6) domain family member 5
chr17_+_57970469 0.02 ENST00000443572.2
ENST00000406116.3
ENST00000225577.4
ENST00000393021.3
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
chr20_+_44657845 0.02 ENST00000243964.3
SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr3_+_167453026 0.02 ENST00000472941.1
SERPINI1
serpin peptidase inhibitor, clade I (neuroserpin), member 1
chr14_+_75746664 0.02 ENST00000557139.1
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr17_-_26220366 0.02 ENST00000460380.2
ENST00000508862.1
ENST00000379102.3
ENST00000582441.1
LYRM9
RP1-66C13.4
LYR motif containing 9
Uncharacterized protein
chr13_-_103053946 0.02 ENST00000376131.4
FGF14
fibroblast growth factor 14
chr4_-_102268484 0.02 ENST00000394853.4
PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chrX_-_11445856 0.02 ENST00000380736.1
ARHGAP6
Rho GTPase activating protein 6
chr8_+_22435762 0.01 ENST00000456545.1
PDLIM2
PDZ and LIM domain 2 (mystique)
chr4_-_102268708 0.01 ENST00000525819.1
PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr11_-_33891362 0.01 ENST00000395833.3
LMO2
LIM domain only 2 (rhombotin-like 1)
chrM_+_10758 0.01 ENST00000361381.2
MT-ND4
mitochondrially encoded NADH dehydrogenase 4
chr2_-_40680578 0.01 ENST00000455476.1
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr11_-_74660159 0.01 ENST00000527087.1
ENST00000321448.8
ENST00000340360.6
XRRA1
X-ray radiation resistance associated 1
chr2_+_171571827 0.01 ENST00000375281.3
SP5
Sp5 transcription factor
chr18_-_53068782 0.01 ENST00000569012.1
TCF4
transcription factor 4
chr14_-_62217779 0.01 ENST00000554254.1
HIF1A-AS2
HIF1A antisense RNA 2
chr18_-_56296182 0.01 ENST00000361673.3
ALPK2
alpha-kinase 2
chr4_-_114682719 0.01 ENST00000394522.3
CAMK2D
calcium/calmodulin-dependent protein kinase II delta
chr20_+_2517253 0.01 ENST00000358864.1
TMC2
transmembrane channel-like 2
chr8_+_56014949 0.00 ENST00000327381.6
XKR4
XK, Kell blood group complex subunit-related family, member 4
chr2_+_210636697 0.00 ENST00000439458.1
ENST00000272845.6
UNC80
unc-80 homolog (C. elegans)

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0031247 actin rod assembly(GO:0031247)
0.1 0.4 GO:0016103 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.1 0.2 GO:0051866 general adaptation syndrome(GO:0051866)
0.1 0.2 GO:0035621 ER to Golgi ceramide transport(GO:0035621)
0.1 0.6 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.3 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.3 GO:1902896 terminal web assembly(GO:1902896)
0.0 0.1 GO:0035283 rhombomere 3 development(GO:0021569) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.1 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.0 0.2 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.3 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.5 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.0 0.3 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.2 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.0 0.1 GO:0060032 notochord regression(GO:0060032)
0.0 0.2 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.0 0.1 GO:0043449 cellular alkene metabolic process(GO:0043449)
0.0 0.2 GO:1905232 cellular response to L-glutamate(GO:1905232)
0.0 0.1 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.2 GO:1900165 adiponectin secretion(GO:0070162) regulation of adiponectin secretion(GO:0070163) negative regulation of monocyte chemotactic protein-1 production(GO:0071638) negative regulation of interleukin-6 secretion(GO:1900165)
0.0 0.1 GO:0002447 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308)
0.0 0.3 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.2 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.0 0.4 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.1 GO:0070602 regulation of centromeric sister chromatid cohesion(GO:0070602)
0.0 0.1 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.1 GO:0035803 egg coat formation(GO:0035803)
0.0 0.1 GO:2000784 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.0 0.1 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 0.1 GO:0033563 dorsal/ventral axon guidance(GO:0033563)
0.0 0.1 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.0 0.6 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.1 GO:0046373 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.0 0.1 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.0 0.2 GO:0002158 osteoclast proliferation(GO:0002158)
0.0 0.0 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.0 0.6 GO:0007140 male meiosis(GO:0007140)
0.0 0.3 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.1 GO:0002860 positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0097486 multivesicular body lumen(GO:0097486)
0.0 0.2 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.0 0.3 GO:1990357 terminal web(GO:1990357)
0.0 0.2 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.0 0.1 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.4 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.3 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.1 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.2 GO:0042025 host cell nucleus(GO:0042025)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.1 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.1 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.3 GO:0071682 endoplasmic reticulum chaperone complex(GO:0034663) endocytic vesicle lumen(GO:0071682)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.2 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.0 0.2 GO:0097001 ceramide binding(GO:0097001)
0.0 0.3 GO:0046790 virion binding(GO:0046790)
0.0 0.2 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.0 0.2 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.3 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.2 GO:0005549 odorant binding(GO:0005549)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.1 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.2 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.6 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.1 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.0 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.1 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 0.1 GO:0032190 acrosin binding(GO:0032190)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR