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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for TCF7L2

Z-value: 0.53

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Transcription factors associated with TCF7L2

Gene Symbol Gene ID Gene Info
TCF7L2
ENSG00000148737.11 transcription factor 7 like 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TCF7L2hg19_v2_chr10_+_114709999_1147100310.982.1e-02Click!

Activity profile of TCF7L2 motif

Sorted Z-values of TCF7L2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_+_32579271 0.39 ENST00000518084.1
NRG1
neuregulin 1
chr5_-_16936340 0.27 ENST00000507288.1
ENST00000513610.1
MYO10
myosin X
chr14_+_64565442 0.25 ENST00000553308.1
SYNE2
spectrin repeat containing, nuclear envelope 2
chr15_+_96897466 0.25 ENST00000558382.1
ENST00000558499.1
RP11-522B15.3
RP11-522B15.3
chr16_+_53242350 0.24 ENST00000565442.1
CHD9
chromodomain helicase DNA binding protein 9
chr8_+_29953163 0.22 ENST00000518192.1
LEPROTL1
leptin receptor overlapping transcript-like 1
chr17_+_70026795 0.22 ENST00000472655.2
ENST00000538810.1
RP11-84E24.3
long intergenic non-protein coding RNA 1152
chr17_+_42081914 0.21 ENST00000293404.3
ENST00000589767.1
NAGS
N-acetylglutamate synthase
chr21_+_18811205 0.20 ENST00000440664.1
C21orf37
chromosome 21 open reading frame 37
chr5_+_66300464 0.19 ENST00000436277.1
MAST4
microtubule associated serine/threonine kinase family member 4
chr13_+_76334795 0.19 ENST00000526202.1
ENST00000465261.2
LMO7
LIM domain 7
chrX_-_43832711 0.19 ENST00000378062.5
NDP
Norrie disease (pseudoglioma)
chr4_-_157892055 0.18 ENST00000422544.2
PDGFC
platelet derived growth factor C
chr7_+_110731062 0.17 ENST00000308478.5
ENST00000451085.1
ENST00000422987.3
ENST00000421101.1
LRRN3
leucine rich repeat neuronal 3
chr17_+_75447326 0.17 ENST00000591088.1
SEPT9
septin 9
chr13_+_76334567 0.17 ENST00000321797.8
LMO7
LIM domain 7
chr8_+_29952914 0.17 ENST00000321250.8
ENST00000518001.1
ENST00000520682.1
ENST00000442880.2
ENST00000523116.1
LEPROTL1
leptin receptor overlapping transcript-like 1
chr17_-_40169659 0.17 ENST00000457167.4
DNAJC7
DnaJ (Hsp40) homolog, subfamily C, member 7
chr6_+_12008986 0.17 ENST00000491710.1
HIVEP1
human immunodeficiency virus type I enhancer binding protein 1
chr10_+_114710516 0.17 ENST00000542695.1
ENST00000346198.4
TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr15_+_101402041 0.16 ENST00000558475.1
ENST00000558641.1
ENST00000559673.1
RP11-66B24.1
RP11-66B24.1
chr2_+_71357744 0.16 ENST00000498451.2
MPHOSPH10
M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)
chr8_+_32579321 0.16 ENST00000522402.1
NRG1
neuregulin 1
chr16_+_19222479 0.15 ENST00000568433.1
SYT17
synaptotagmin XVII
chrX_+_100645812 0.15 ENST00000427805.2
ENST00000553110.3
ENST00000392994.3
ENST00000409338.1
ENST00000409170.3
RPL36A
RPL36A-HNRNPH2
ribosomal protein L36a
RPL36A-HNRNPH2 readthrough
chrX_+_100646190 0.15 ENST00000471855.1
RPL36A
ribosomal protein L36a
chr9_+_128510454 0.15 ENST00000491787.3
ENST00000447726.2
PBX3
pre-B-cell leukemia homeobox 3
chr10_-_14614311 0.15 ENST00000479731.1
ENST00000468492.1
FAM107B
family with sequence similarity 107, member B
chr7_-_75452673 0.15 ENST00000416943.1
CCL24
chemokine (C-C motif) ligand 24
chr9_+_97766469 0.14 ENST00000433691.2
C9orf3
chromosome 9 open reading frame 3
chr13_+_76334498 0.14 ENST00000534657.1
LMO7
LIM domain 7
chr5_+_60628074 0.14 ENST00000252744.5
ZSWIM6
zinc finger, SWIM-type containing 6
chr17_-_56065484 0.13 ENST00000581208.1
VEZF1
vascular endothelial zinc finger 1
chr10_+_114709999 0.13 ENST00000355995.4
ENST00000545257.1
ENST00000543371.1
ENST00000536810.1
ENST00000355717.4
ENST00000538897.1
ENST00000534894.1
TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr2_+_69240511 0.12 ENST00000409349.3
ANTXR1
anthrax toxin receptor 1
chr3_-_113464906 0.12 ENST00000477813.1
NAA50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr2_+_71357434 0.11 ENST00000244230.2
MPHOSPH10
M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)
chr2_+_11679963 0.11 ENST00000263834.5
GREB1
growth regulation by estrogen in breast cancer 1
chr6_-_11779403 0.11 ENST00000414691.3
ADTRP
androgen-dependent TFPI-regulating protein
chr10_-_14614122 0.11 ENST00000378465.3
ENST00000452706.2
ENST00000378458.2
FAM107B
family with sequence similarity 107, member B
chr15_-_89764929 0.10 ENST00000268125.5
RLBP1
retinaldehyde binding protein 1
chr14_-_23762777 0.10 ENST00000431326.2
HOMEZ
homeobox and leucine zipper encoding
chr10_-_14614095 0.10 ENST00000482277.1
ENST00000378462.1
FAM107B
family with sequence similarity 107, member B
chr10_+_114710211 0.10 ENST00000349937.2
ENST00000369397.4
TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr8_+_32579341 0.10 ENST00000519240.1
ENST00000539990.1
NRG1
neuregulin 1
chr9_+_125795788 0.09 ENST00000373643.5
RABGAP1
RAB GTPase activating protein 1
chr17_+_1674982 0.09 ENST00000572048.1
ENST00000573763.1
SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr11_-_76155618 0.09 ENST00000530759.1
RP11-111M22.3
RP11-111M22.3
chr7_-_27219849 0.09 ENST00000396344.4
HOXA10
homeobox A10
chr17_-_79919713 0.09 ENST00000425009.1
NOTUM
notum pectinacetylesterase homolog (Drosophila)
chr10_+_7745303 0.09 ENST00000429820.1
ENST00000379587.4
ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr4_-_123542224 0.09 ENST00000264497.3
IL21
interleukin 21
chr9_+_97766409 0.09 ENST00000425634.2
C9orf3
chromosome 9 open reading frame 3
chr18_+_46065570 0.09 ENST00000591412.1
CTIF
CBP80/20-dependent translation initiation factor
chr17_-_47308128 0.09 ENST00000413580.1
ENST00000511066.1
PHOSPHO1
phosphatase, orphan 1
chr4_-_157892498 0.09 ENST00000502773.1
PDGFC
platelet derived growth factor C
chr5_+_133450365 0.08 ENST00000342854.5
ENST00000321603.6
ENST00000321584.4
ENST00000378564.1
ENST00000395029.1
TCF7
transcription factor 7 (T-cell specific, HMG-box)
chr15_+_93447675 0.08 ENST00000536619.1
CHD2
chromodomain helicase DNA binding protein 2
chr16_+_53407383 0.08 ENST00000566383.1
RP11-44F14.2
RP11-44F14.2
chr15_+_43985725 0.08 ENST00000413453.2
CKMT1A
creatine kinase, mitochondrial 1A
chr4_+_183065793 0.08 ENST00000512480.1
TENM3
teneurin transmembrane protein 3
chr4_+_95972822 0.08 ENST00000509540.1
ENST00000440890.2
BMPR1B
bone morphogenetic protein receptor, type IB
chr3_-_79068138 0.08 ENST00000495273.1
ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr12_+_85673868 0.08 ENST00000316824.3
ALX1
ALX homeobox 1
chr5_+_131593364 0.08 ENST00000253754.3
ENST00000379018.3
PDLIM4
PDZ and LIM domain 4
chr4_-_85419603 0.08 ENST00000295886.4
NKX6-1
NK6 homeobox 1
chr10_-_14613968 0.08 ENST00000488576.1
ENST00000472095.1
FAM107B
family with sequence similarity 107, member B
chr11_+_111945011 0.08 ENST00000532163.1
ENST00000280352.9
ENST00000530104.1
ENST00000526879.1
ENST00000393047.3
ENST00000525785.1
C11orf57
chromosome 11 open reading frame 57
chr8_-_16859690 0.07 ENST00000180166.5
FGF20
fibroblast growth factor 20
chr4_-_109684120 0.07 ENST00000512646.1
ENST00000411864.2
ENST00000296486.3
ENST00000510706.1
ETNPPL
ethanolamine-phosphate phospho-lyase
chr11_+_7597639 0.07 ENST00000533792.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr5_+_112074029 0.07 ENST00000512211.2
APC
adenomatous polyposis coli
chr4_+_170581213 0.07 ENST00000507875.1
CLCN3
chloride channel, voltage-sensitive 3
chr13_-_36429763 0.07 ENST00000379893.1
DCLK1
doublecortin-like kinase 1
chr3_+_183353356 0.07 ENST00000242810.6
ENST00000493074.1
ENST00000437402.1
ENST00000454495.2
ENST00000473045.1
ENST00000468101.1
ENST00000427201.2
ENST00000482138.1
ENST00000454652.2
KLHL24
kelch-like family member 24
chr12_+_122326662 0.07 ENST00000261817.2
ENST00000538613.1
ENST00000542602.1
PSMD9
proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
chr4_+_87857538 0.07 ENST00000511442.1
AFF1
AF4/FMR2 family, member 1
chr9_-_15510287 0.07 ENST00000397519.2
PSIP1
PC4 and SFRS1 interacting protein 1
chr2_-_55646957 0.06 ENST00000263630.8
CCDC88A
coiled-coil domain containing 88A
chr3_-_45957534 0.06 ENST00000536047.1
LZTFL1
leucine zipper transcription factor-like 1
chr2_-_71357344 0.06 ENST00000494660.2
ENST00000244217.5
ENST00000486135.1
MCEE
methylmalonyl CoA epimerase
chr2_-_55647057 0.06 ENST00000436346.1
CCDC88A
coiled-coil domain containing 88A
chrX_+_123097014 0.06 ENST00000394478.1
STAG2
stromal antigen 2
chr12_-_109797249 0.06 ENST00000538041.1
RP11-256L11.1
RP11-256L11.1
chr10_-_75351088 0.06 ENST00000451492.1
ENST00000413442.1
USP54
ubiquitin specific peptidase 54
chrX_+_2670066 0.06 ENST00000381174.5
ENST00000419513.2
ENST00000426774.1
XG
Xg blood group
chr10_+_115312766 0.06 ENST00000351270.3
HABP2
hyaluronan binding protein 2
chr2_+_233385173 0.06 ENST00000449534.2
PRSS56
protease, serine, 56
chr2_+_201936458 0.06 ENST00000237889.4
NDUFB3
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa
chr1_+_110091189 0.06 ENST00000369851.4
GNAI3
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
chr3_+_57875711 0.06 ENST00000442599.2
SLMAP
sarcolemma associated protein
chr10_-_25241499 0.06 ENST00000376378.1
ENST00000376376.3
ENST00000320152.6
PRTFDC1
phosphoribosyl transferase domain containing 1
chr7_-_148725544 0.06 ENST00000413966.1
PDIA4
protein disulfide isomerase family A, member 4
chr21_+_30671690 0.05 ENST00000399921.1
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr10_-_104179682 0.05 ENST00000406432.1
PSD
pleckstrin and Sec7 domain containing
chr17_-_56065540 0.05 ENST00000583932.1
VEZF1
vascular endothelial zinc finger 1
chr6_-_135424186 0.05 ENST00000529882.1
HBS1L
HBS1-like (S. cerevisiae)
chr14_-_53258180 0.05 ENST00000554230.1
GNPNAT1
glucosamine-phosphate N-acetyltransferase 1
chr4_-_157892167 0.05 ENST00000541126.1
PDGFC
platelet derived growth factor C
chr1_+_61330931 0.05 ENST00000371191.1
NFIA
nuclear factor I/A
chr5_-_16742330 0.05 ENST00000505695.1
ENST00000427430.2
MYO10
myosin X
chrX_-_10588459 0.05 ENST00000380782.2
MID1
midline 1 (Opitz/BBB syndrome)
chr1_+_151138526 0.05 ENST00000368902.1
SCNM1
sodium channel modifier 1
chr22_+_31742875 0.05 ENST00000504184.2
AC005003.1
CDNA FLJ20464 fis, clone KAT06158; HCG1777549; Uncharacterized protein
chr15_-_31393910 0.05 ENST00000397795.2
ENST00000256552.6
ENST00000559179.1
TRPM1
transient receptor potential cation channel, subfamily M, member 1
chr20_-_17511962 0.05 ENST00000377873.3
BFSP1
beaded filament structural protein 1, filensin
chr12_+_70760056 0.05 ENST00000258111.4
KCNMB4
potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr8_-_95220775 0.05 ENST00000441892.2
ENST00000521491.1
ENST00000027335.3
CDH17
cadherin 17, LI cadherin (liver-intestine)
chr7_-_27213893 0.05 ENST00000283921.4
HOXA10
homeobox A10
chr11_-_94965667 0.05 ENST00000542176.1
ENST00000278499.2
SESN3
sestrin 3
chr17_+_34848049 0.05 ENST00000588902.1
ENST00000591067.1
ZNHIT3
zinc finger, HIT-type containing 3
chr6_-_24645956 0.05 ENST00000543707.1
KIAA0319
KIAA0319
chr10_-_105677427 0.04 ENST00000369764.1
OBFC1
oligonucleotide/oligosaccharide-binding fold containing 1
chr5_+_54455946 0.04 ENST00000503787.1
ENST00000296734.6
ENST00000515370.1
GPX8
glutathione peroxidase 8 (putative)
chr2_+_69240415 0.04 ENST00000409829.3
ANTXR1
anthrax toxin receptor 1
chrX_-_39956656 0.04 ENST00000397354.3
ENST00000378444.4
BCOR
BCL6 corepressor
chr2_+_69240302 0.04 ENST00000303714.4
ANTXR1
anthrax toxin receptor 1
chr4_-_65275162 0.04 ENST00000381210.3
ENST00000507440.1
TECRL
trans-2,3-enoyl-CoA reductase-like
chr11_-_6677018 0.04 ENST00000299441.3
DCHS1
dachsous cadherin-related 1
chr10_+_101542462 0.04 ENST00000370449.4
ENST00000370434.1
ABCC2
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr1_-_54304212 0.04 ENST00000540001.1
NDC1
NDC1 transmembrane nucleoporin
chr3_+_57875738 0.04 ENST00000417128.1
ENST00000438794.1
SLMAP
sarcolemma associated protein
chr3_-_33686925 0.04 ENST00000485378.2
ENST00000313350.6
ENST00000487200.1
CLASP2
cytoplasmic linker associated protein 2
chrX_-_100183894 0.04 ENST00000328526.5
ENST00000372956.2
XKRX
XK, Kell blood group complex subunit-related, X-linked
chr1_-_40367530 0.04 ENST00000372816.2
ENST00000372815.1
MYCL
v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
chr14_+_59100774 0.04 ENST00000556859.1
ENST00000421793.1
DACT1
dishevelled-binding antagonist of beta-catenin 1
chr5_+_102201509 0.04 ENST00000348126.2
ENST00000379787.4
PAM
peptidylglycine alpha-amidating monooxygenase
chr15_+_43885252 0.03 ENST00000453782.1
ENST00000300283.6
ENST00000437924.1
ENST00000450086.2
CKMT1B
creatine kinase, mitochondrial 1B
chr4_+_86525299 0.03 ENST00000512201.1
ARHGAP24
Rho GTPase activating protein 24
chr4_-_69215467 0.03 ENST00000579690.1
YTHDC1
YTH domain containing 1
chr2_+_33701286 0.03 ENST00000403687.3
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr2_+_201936707 0.03 ENST00000433898.1
ENST00000454214.1
NDUFB3
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa
chr13_+_24144796 0.03 ENST00000403372.2
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr17_+_59529743 0.03 ENST00000589003.1
ENST00000393853.4
TBX4
T-box 4
chr7_+_99613212 0.03 ENST00000426572.1
ENST00000535170.1
ZKSCAN1
zinc finger with KRAB and SCAN domains 1
chr1_+_180199393 0.03 ENST00000263726.2
LHX4
LIM homeobox 4
chr1_-_54303949 0.03 ENST00000234725.8
NDC1
NDC1 transmembrane nucleoporin
chr12_-_133464118 0.03 ENST00000540963.1
CHFR
checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
chr17_+_38337491 0.03 ENST00000538981.1
RAPGEFL1
Rap guanine nucleotide exchange factor (GEF)-like 1
chr2_+_204732487 0.03 ENST00000302823.3
CTLA4
cytotoxic T-lymphocyte-associated protein 4
chr17_-_40170506 0.03 ENST00000589773.1
ENST00000590348.1
DNAJC7
DnaJ (Hsp40) homolog, subfamily C, member 7
chr12_-_12491608 0.03 ENST00000545735.1
MANSC1
MANSC domain containing 1
chrX_-_32173579 0.03 ENST00000359836.1
ENST00000343523.2
ENST00000378707.3
ENST00000541735.1
ENST00000474231.1
DMD
dystrophin
chr12_+_122326630 0.03 ENST00000541212.1
ENST00000340175.5
PSMD9
proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
chrX_-_10588595 0.03 ENST00000423614.1
ENST00000317552.4
MID1
midline 1 (Opitz/BBB syndrome)
chr7_-_16505440 0.03 ENST00000307068.4
SOSTDC1
sclerostin domain containing 1
chr15_+_43985084 0.03 ENST00000434505.1
ENST00000411750.1
CKMT1A
creatine kinase, mitochondrial 1A
chr9_-_100707116 0.03 ENST00000259456.3
HEMGN
hemogen
chr1_+_78383813 0.03 ENST00000342754.5
NEXN
nexilin (F actin binding protein)
chr13_-_67802549 0.03 ENST00000328454.5
ENST00000377865.2
PCDH9
protocadherin 9
chrX_-_122866874 0.03 ENST00000245838.8
ENST00000355725.4
THOC2
THO complex 2
chr17_+_37618257 0.03 ENST00000447079.4
CDK12
cyclin-dependent kinase 12
chr10_+_105005644 0.02 ENST00000441178.2
RP11-332O19.5
ribulose-5-phosphate-3-epimerase-like 1
chr6_+_64281906 0.02 ENST00000370651.3
PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr6_+_35704855 0.02 ENST00000288065.2
ENST00000373866.3
ARMC12
armadillo repeat containing 12
chr9_+_116225999 0.02 ENST00000317613.6
RGS3
regulator of G-protein signaling 3
chr3_+_29323043 0.02 ENST00000452462.1
ENST00000456853.1
RBMS3
RNA binding motif, single stranded interacting protein 3
chrX_+_69488174 0.02 ENST00000480877.2
ENST00000307959.8
ARR3
arrestin 3, retinal (X-arrestin)
chr10_+_115312825 0.02 ENST00000537906.1
ENST00000541666.1
HABP2
hyaluronan binding protein 2
chr17_+_48611853 0.02 ENST00000507709.1
ENST00000515126.1
ENST00000507467.1
EPN3
epsin 3
chr21_+_30672433 0.02 ENST00000451655.1
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr12_-_54694807 0.02 ENST00000435572.2
NFE2
nuclear factor, erythroid 2
chr3_-_45957088 0.02 ENST00000539217.1
LZTFL1
leucine zipper transcription factor-like 1
chr11_-_62572901 0.02 ENST00000439713.2
ENST00000531131.1
ENST00000530875.1
ENST00000531709.2
ENST00000294172.2
NXF1
nuclear RNA export factor 1
chr14_+_75230011 0.02 ENST00000552421.1
ENST00000325680.7
ENST00000238571.3
YLPM1
YLP motif containing 1
chr15_+_57511609 0.02 ENST00000543579.1
ENST00000537840.1
ENST00000343827.3
TCF12
transcription factor 12
chr15_-_65670360 0.02 ENST00000327987.4
IGDCC3
immunoglobulin superfamily, DCC subclass, member 3
chr12_+_6982725 0.02 ENST00000433346.1
LRRC23
leucine rich repeat containing 23
chr6_-_112575758 0.02 ENST00000431543.2
ENST00000453937.2
ENST00000368638.4
ENST00000389463.4
LAMA4
laminin, alpha 4
chrX_+_69488155 0.02 ENST00000374495.3
ARR3
arrestin 3, retinal (X-arrestin)
chr12_+_52056548 0.02 ENST00000545061.1
ENST00000355133.3
SCN8A
sodium channel, voltage gated, type VIII, alpha subunit
chr10_+_114710425 0.02 ENST00000352065.5
ENST00000369395.1
TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr2_+_48796120 0.02 ENST00000394754.1
STON1-GTF2A1L
STON1-GTF2A1L readthrough
chr18_+_29769978 0.02 ENST00000269202.6
ENST00000581447.1
MEP1B
meprin A, beta
chr4_-_146859787 0.02 ENST00000508784.1
ZNF827
zinc finger protein 827
chr17_-_38020392 0.02 ENST00000346872.3
ENST00000439167.2
ENST00000377945.3
ENST00000394189.2
ENST00000377944.3
ENST00000377958.2
ENST00000535189.1
ENST00000377952.2
IKZF3
IKAROS family zinc finger 3 (Aiolos)
chr14_+_68189190 0.01 ENST00000539142.1
RDH12
retinol dehydrogenase 12 (all-trans/9-cis/11-cis)
chr6_+_152130240 0.01 ENST00000427531.2
ESR1
estrogen receptor 1
chr1_-_109935819 0.01 ENST00000538502.1
SORT1
sortilin 1
chr6_-_112575687 0.01 ENST00000521398.1
ENST00000424408.2
ENST00000243219.3
LAMA4
laminin, alpha 4
chr2_+_177028805 0.01 ENST00000249440.3
HOXD3
homeobox D3
chr5_-_175815565 0.01 ENST00000509257.1
ENST00000507413.1
ENST00000510123.1
NOP16
NOP16 nucleolar protein
chr17_-_73389737 0.01 ENST00000392563.1
GRB2
growth factor receptor-bound protein 2
chr5_-_148930960 0.01 ENST00000261798.5
ENST00000377843.2
CSNK1A1
casein kinase 1, alpha 1
chr5_+_175288631 0.01 ENST00000509837.1
CPLX2
complexin 2
chr4_+_78078304 0.01 ENST00000316355.5
ENST00000354403.5
ENST00000502280.1
CCNG2
cyclin G2
chr1_-_54303934 0.01 ENST00000537333.1
NDC1
NDC1 transmembrane nucleoporin
chr7_-_111428957 0.01 ENST00000417165.1
DOCK4
dedicator of cytokinesis 4
chr4_-_36245561 0.01 ENST00000506189.1
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr4_-_120243545 0.01 ENST00000274024.3
FABP2
fatty acid binding protein 2, intestinal
chr6_-_128222103 0.01 ENST00000434358.1
ENST00000543064.1
ENST00000368248.2
THEMIS
thymocyte selection associated
chr7_-_148725733 0.01 ENST00000286091.4
PDIA4
protein disulfide isomerase family A, member 4
chr4_-_139163491 0.01 ENST00000280612.5
SLC7A11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr2_-_9770706 0.01 ENST00000381844.4
YWHAQ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
chr11_+_45944190 0.01 ENST00000401752.1
ENST00000389968.3
ENST00000325468.5
ENST00000536139.1
GYLTL1B
glycosyltransferase-like 1B
chr17_-_63557759 0.01 ENST00000307078.5
AXIN2
axin 2
chr7_-_148581251 0.01 ENST00000478654.1
ENST00000460911.1
ENST00000350995.2
EZH2
enhancer of zeste homolog 2 (Drosophila)
chr2_-_233641265 0.01 ENST00000438786.1
ENST00000409779.1
ENST00000233826.3
KCNJ13
potassium inwardly-rectifying channel, subfamily J, member 13
chr9_-_23826298 0.01 ENST00000380117.1
ELAVL2
ELAV like neuron-specific RNA binding protein 2
chr1_-_201096312 0.01 ENST00000449188.2
ASCL5
achaete-scute family bHLH transcription factor 5

Network of associatons between targets according to the STRING database.

First level regulatory network of TCF7L2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.1 0.2 GO:1901202 negative regulation of extracellular matrix assembly(GO:1901202)
0.1 0.4 GO:0048625 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) myoblast fate commitment(GO:0048625) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.1 0.2 GO:0007388 anterior compartment pattern formation(GO:0007387) posterior compartment specification(GO:0007388)
0.0 0.4 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.0 0.1 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.0 0.2 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.1 GO:1990697 protein depalmitoleylation(GO:1990697)
0.0 0.1 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.0 0.1 GO:1903568 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.0 0.3 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.1 GO:0070632 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.0 0.2 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.1 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.0 0.1 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.0 0.3 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.1 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.0 0.1 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.1 GO:0009730 glandular epithelial cell maturation(GO:0002071) detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594) type B pancreatic cell maturation(GO:0072560)
0.0 0.0 GO:0003192 mitral valve formation(GO:0003192)
0.0 0.0 GO:0050787 antibiotic metabolic process(GO:0016999) detoxification of mercury ion(GO:0050787)
0.0 0.1 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.0 0.0 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
0.0 0.2 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.1 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.1 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.0 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.0 GO:0021526 medial motor column neuron differentiation(GO:0021526)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0034457 Mpp10 complex(GO:0034457)
0.1 0.4 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369) beta-catenin-TCF complex(GO:1990907)
0.0 0.1 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
0.0 0.8 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.6 GO:0030673 axolemma(GO:0030673)
0.0 0.0 GO:0035838 growing cell tip(GO:0035838)
0.0 0.1 GO:0031415 NatA complex(GO:0031415)
0.0 0.1 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.1 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.0 0.2 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.1 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.3 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.5 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.1 GO:1990699 palmitoleyl hydrolase activity(GO:1990699)
0.0 0.1 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.0 0.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.0 GO:0005427 proton-dependent oligopeptide secondary active transmembrane transporter activity(GO:0005427) secondary active oligopeptide transmembrane transporter activity(GO:0015322)
0.0 0.1 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID ERBB NETWORK PATHWAY ErbB receptor signaling network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.5 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling