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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for TFAP2B

Z-value: 0.63

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Transcription factors associated with TFAP2B

Gene Symbol Gene ID Gene Info
TFAP2B
ENSG00000008196.8 transcription factor AP-2 beta

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TFAP2Bhg19_v2_chr6_+_50786414_50786439-0.955.5e-02Click!

Activity profile of TFAP2B motif

Sorted Z-values of TFAP2B motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_100065686 0.65 ENST00000423266.1
ENST00000456330.1
TSC22D4
TSC22 domain family, member 4
chr4_-_1723040 0.64 ENST00000382936.3
ENST00000536901.1
ENST00000303277.2
TMEM129
transmembrane protein 129
chr6_+_33378517 0.51 ENST00000428274.1
PHF1
PHD finger protein 1
chr9_+_130922537 0.48 ENST00000372994.1
C9orf16
chromosome 9 open reading frame 16
chr2_-_220408260 0.46 ENST00000373891.2
CHPF
chondroitin polymerizing factor
chr11_-_64052111 0.44 ENST00000394532.3
ENST00000394531.3
ENST00000309032.3
BAD
BCL2-associated agonist of cell death
chr17_-_8093471 0.43 ENST00000389017.4
C17orf59
chromosome 17 open reading frame 59
chr19_+_41107249 0.40 ENST00000396819.3
LTBP4
latent transforming growth factor beta binding protein 4
chr2_-_220408430 0.39 ENST00000243776.6
CHPF
chondroitin polymerizing factor
chr19_+_47778119 0.36 ENST00000552360.2
PRR24
proline rich 24
chr8_-_21988558 0.34 ENST00000312841.8
HR
hair growth associated
chr10_+_104178946 0.32 ENST00000432590.1
FBXL15
F-box and leucine-rich repeat protein 15
chr16_-_28223229 0.31 ENST00000566073.1
XPO6
exportin 6
chr6_+_33378738 0.30 ENST00000374512.3
ENST00000374516.3
PHF1
PHD finger protein 1
chr17_-_61777459 0.30 ENST00000578993.1
ENST00000583211.1
ENST00000259006.3
LIMD2
LIM domain containing 2
chr1_+_155179012 0.29 ENST00000609421.1
MTX1
metaxin 1
chr8_+_21906433 0.29 ENST00000522148.1
DMTN
dematin actin binding protein
chr17_+_18163848 0.28 ENST00000323019.4
ENST00000578174.1
ENST00000395704.4
ENST00000395703.4
ENST00000578621.1
ENST00000579341.1
MIEF2
mitochondrial elongation factor 2
chr6_-_31763276 0.27 ENST00000440048.1
VARS
valyl-tRNA synthetase
chr1_-_1677358 0.27 ENST00000355439.2
ENST00000400924.1
ENST00000246421.4
SLC35E2
solute carrier family 35, member E2
chr5_-_176730733 0.26 ENST00000504395.1
RAB24
RAB24, member RAS oncogene family
chr17_+_1627834 0.26 ENST00000419248.1
ENST00000418841.1
WDR81
WD repeat domain 81
chr2_+_130939827 0.26 ENST00000409255.1
ENST00000455239.1
MZT2B
mitotic spindle organizing protein 2B
chr1_+_155178481 0.26 ENST00000368376.3
MTX1
metaxin 1
chr1_-_2345236 0.25 ENST00000508384.1
PEX10
peroxisomal biogenesis factor 10
chr17_-_17726907 0.25 ENST00000423161.3
SREBF1
sterol regulatory element binding transcription factor 1
chr19_+_7710774 0.24 ENST00000602355.1
STXBP2
syntaxin binding protein 2
chr2_+_232575168 0.23 ENST00000440384.1
PTMA
prothymosin, alpha
chr17_-_7760457 0.23 ENST00000576384.1
LSMD1
LSM domain containing 1
chr19_+_13228917 0.23 ENST00000586171.1
NACC1
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
chr12_+_48152774 0.22 ENST00000549243.1
SLC48A1
solute carrier family 48 (heme transporter), member 1
chr5_+_172068232 0.22 ENST00000520919.1
ENST00000522853.1
ENST00000369800.5
NEURL1B
neuralized E3 ubiquitin protein ligase 1B
chr1_+_155178518 0.22 ENST00000316721.4
MTX1
metaxin 1
chr8_+_142402089 0.22 ENST00000521578.1
ENST00000520105.1
ENST00000523147.1
PTP4A3
protein tyrosine phosphatase type IVA, member 3
chr20_+_62327996 0.22 ENST00000369996.1
TNFRSF6B
tumor necrosis factor receptor superfamily, member 6b, decoy
chr14_+_24458093 0.22 ENST00000558753.1
ENST00000537912.1
DHRS4L2
dehydrogenase/reductase (SDR family) member 4 like 2
chr7_-_86849836 0.21 ENST00000455575.1
TMEM243
transmembrane protein 243, mitochondrial
chr19_-_46145696 0.21 ENST00000588172.1
EML2
echinoderm microtubule associated protein like 2
chr16_+_30960375 0.21 ENST00000318663.4
ENST00000566237.1
ENST00000562699.1
ORAI3
ORAI calcium release-activated calcium modulator 3
chr10_+_103825080 0.21 ENST00000299238.5
HPS6
Hermansky-Pudlak syndrome 6
chr17_-_72869086 0.21 ENST00000581530.1
ENST00000420580.2
ENST00000455107.2
ENST00000413947.2
ENST00000581219.1
ENST00000582944.1
FDXR
ferredoxin reductase
chr17_-_72869140 0.20 ENST00000583917.1
ENST00000293195.5
ENST00000442102.2
FDXR
ferredoxin reductase
chr20_-_49639631 0.20 ENST00000424171.1
ENST00000439216.1
ENST00000371571.4
KCNG1
potassium voltage-gated channel, subfamily G, member 1
chr14_+_65171099 0.20 ENST00000247226.7
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr9_+_135037334 0.19 ENST00000393229.3
ENST00000360670.3
ENST00000393228.4
ENST00000372179.3
NTNG2
netrin G2
chr11_+_62379194 0.19 ENST00000525801.1
ENST00000534093.1
ROM1
retinal outer segment membrane protein 1
chr1_-_44497118 0.19 ENST00000537678.1
ENST00000466926.1
SLC6A9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr22_+_42665742 0.19 ENST00000332965.3
ENST00000415205.1
ENST00000446578.1
Z83851.3
Z83851.3
chr20_-_30539773 0.19 ENST00000202017.4
PDRG1
p53 and DNA-damage regulated 1
chr9_+_136325089 0.18 ENST00000291722.7
ENST00000316948.4
ENST00000540581.1
CACFD1
calcium channel flower domain containing 1
chr6_+_30294186 0.18 ENST00000458516.1
TRIM39
tripartite motif containing 39
chr19_+_39989535 0.18 ENST00000356433.5
DLL3
delta-like 3 (Drosophila)
chr5_-_134369973 0.18 ENST00000265340.7
PITX1
paired-like homeodomain 1
chr1_-_21948906 0.18 ENST00000374761.2
ENST00000599760.1
RAP1GAP
RAP1 GTPase activating protein
chr1_-_156399184 0.17 ENST00000368243.1
ENST00000357975.4
ENST00000310027.5
ENST00000400991.2
C1orf61
chromosome 1 open reading frame 61
chr1_-_1535455 0.17 ENST00000422725.1
C1orf233
chromosome 1 open reading frame 233
chr2_-_132249955 0.17 ENST00000309451.6
MZT2A
mitotic spindle organizing protein 2A
chr11_+_809647 0.17 ENST00000321153.4
RPLP2
ribosomal protein, large, P2
chr16_+_88772866 0.17 ENST00000453996.2
ENST00000312060.5
ENST00000378384.3
ENST00000567949.1
ENST00000564921.1
CTU2
cytosolic thiouridylase subunit 2 homolog (S. pombe)
chr2_-_73511559 0.17 ENST00000521871.1
FBXO41
F-box protein 41
chr19_+_14544099 0.17 ENST00000242783.6
ENST00000586557.1
ENST00000590097.1
PKN1
protein kinase N1
chr22_+_45072925 0.17 ENST00000006251.7
PRR5
proline rich 5 (renal)
chr17_-_73874654 0.17 ENST00000254816.2
TRIM47
tripartite motif containing 47
chr14_+_23341513 0.17 ENST00000546834.1
LRP10
low density lipoprotein receptor-related protein 10
chr11_-_62379752 0.16 ENST00000466671.1
ENST00000466886.1
EML3
echinoderm microtubule associated protein like 3
chr3_-_50360192 0.16 ENST00000442581.1
ENST00000447092.1
ENST00000357750.4
HYAL2
hyaluronoglucosaminidase 2
chr19_+_13229126 0.16 ENST00000292431.4
NACC1
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
chr19_+_41119794 0.16 ENST00000593463.1
LTBP4
latent transforming growth factor beta binding protein 4
chr17_+_36861735 0.16 ENST00000378137.5
ENST00000325718.7
MLLT6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr15_+_73976715 0.16 ENST00000558689.1
ENST00000560786.2
ENST00000561213.1
ENST00000563584.1
ENST00000561416.1
CD276
CD276 molecule
chr8_-_145018905 0.16 ENST00000398774.2
PLEC
plectin
chr17_-_7760779 0.16 ENST00000335155.5
ENST00000575071.1
LSMD1
LSM domain containing 1
chr22_-_19842330 0.16 ENST00000416337.1
ENST00000328554.4
ENST00000403325.1
ENST00000453108.1
C22orf29
GNB1L
chromosome 22 open reading frame 29
guanine nucleotide binding protein (G protein), beta polypeptide 1-like
chr16_-_67970990 0.16 ENST00000358514.4
PSMB10
proteasome (prosome, macropain) subunit, beta type, 10
chrX_+_48916497 0.16 ENST00000496529.2
ENST00000376396.3
ENST00000422185.2
ENST00000603986.1
ENST00000536628.2
CCDC120
coiled-coil domain containing 120
chr19_-_42724261 0.16 ENST00000595337.1
DEDD2
death effector domain containing 2
chr12_+_133067157 0.16 ENST00000261673.6
FBRSL1
fibrosin-like 1
chr17_-_71308119 0.16 ENST00000439510.2
ENST00000581014.1
ENST00000579611.1
CDC42EP4
CDC42 effector protein (Rho GTPase binding) 4
chr6_-_34664612 0.15 ENST00000374023.3
ENST00000374026.3
C6orf106
chromosome 6 open reading frame 106
chr22_+_45072958 0.15 ENST00000403581.1
PRR5
proline rich 5 (renal)
chr3_-_10052849 0.15 ENST00000437616.1
ENST00000429065.2
AC022007.5
AC022007.5
chr14_+_23340822 0.15 ENST00000359591.4
LRP10
low density lipoprotein receptor-related protein 10
chr19_+_46144884 0.15 ENST00000593161.1
AC006132.1
chromosome 19 open reading frame 83
chr22_-_29663690 0.14 ENST00000406335.1
RHBDD3
rhomboid domain containing 3
chr17_-_27230035 0.14 ENST00000378895.4
ENST00000394901.3
DHRS13
dehydrogenase/reductase (SDR family) member 13
chr12_+_110011571 0.14 ENST00000539696.1
ENST00000228510.3
ENST00000392727.3
MVK
mevalonate kinase
chrX_+_70316005 0.14 ENST00000374259.3
FOXO4
forkhead box O4
chr8_-_146017736 0.14 ENST00000528957.1
RPL8
ribosomal protein L8
chr9_+_116917807 0.14 ENST00000356083.3
COL27A1
collagen, type XXVII, alpha 1
chr16_+_30418910 0.14 ENST00000566625.1
ZNF771
zinc finger protein 771
chr3_-_185216766 0.14 ENST00000296254.3
TMEM41A
transmembrane protein 41A
chr1_+_155051379 0.14 ENST00000418360.2
EFNA3
ephrin-A3
chr5_-_176981417 0.14 ENST00000514747.1
ENST00000443375.2
ENST00000329540.5
FAM193B
family with sequence similarity 193, member B
chr11_-_63536113 0.14 ENST00000433688.1
ENST00000546282.2
C11orf95
RP11-466C23.4
chromosome 11 open reading frame 95
RP11-466C23.4
chr16_+_31085714 0.14 ENST00000300850.5
ENST00000564189.1
ENST00000428260.1
ZNF646
zinc finger protein 646
chr1_+_33207381 0.13 ENST00000401073.2
KIAA1522
KIAA1522
chr12_+_53693466 0.13 ENST00000267103.5
ENST00000548632.1
C12orf10
chromosome 12 open reading frame 10
chr16_-_88772761 0.13 ENST00000567844.1
ENST00000312838.4
RNF166
ring finger protein 166
chr17_+_7255208 0.13 ENST00000333751.3
KCTD11
potassium channel tetramerization domain containing 11
chr10_-_135238076 0.13 ENST00000414069.2
SPRN
shadow of prion protein homolog (zebrafish)
chr1_-_44497024 0.13 ENST00000372306.3
ENST00000372310.3
ENST00000475075.2
SLC6A9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr7_+_65939543 0.13 ENST00000600021.1
AC008267.1
HCG1983814; Uncharacterized protein
chr7_+_150076406 0.13 ENST00000329630.5
ZNF775
zinc finger protein 775
chr9_-_131534160 0.13 ENST00000291900.2
ZER1
zyg-11 related, cell cycle regulator
chr6_+_43139037 0.13 ENST00000265354.4
SRF
serum response factor (c-fos serum response element-binding transcription factor)
chr17_+_36858694 0.13 ENST00000563897.1
CTB-58E17.1
CTB-58E17.1
chr17_-_48133054 0.13 ENST00000499842.1
RP11-1094H24.4
RP11-1094H24.4
chr1_+_33722080 0.13 ENST00000483388.1
ENST00000539719.1
ZNF362
zinc finger protein 362
chr19_-_42758040 0.13 ENST00000593944.1
ERF
Ets2 repressor factor
chr9_+_136325149 0.13 ENST00000542192.1
CACFD1
calcium channel flower domain containing 1
chr19_-_39832563 0.13 ENST00000599274.1
CTC-246B18.10
CTC-246B18.10
chr9_+_131182697 0.13 ENST00000372838.4
ENST00000411852.1
CERCAM
cerebral endothelial cell adhesion molecule
chr14_+_65171315 0.13 ENST00000394691.1
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr3_-_50360165 0.12 ENST00000428028.1
HYAL2
hyaluronoglucosaminidase 2
chr19_+_39989580 0.12 ENST00000596614.1
ENST00000205143.4
DLL3
delta-like 3 (Drosophila)
chr12_+_6493319 0.12 ENST00000536876.1
LTBR
lymphotoxin beta receptor (TNFR superfamily, member 3)
chr8_-_146017765 0.12 ENST00000532702.1
ENST00000394920.2
ENST00000527914.1
RPL8
ribosomal protein L8
chr1_+_161129240 0.12 ENST00000492950.1
USP21
ubiquitin specific peptidase 21
chr22_-_31742218 0.12 ENST00000266269.5
ENST00000405309.3
ENST00000351933.4
PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr5_+_149980622 0.12 ENST00000394243.1
SYNPO
synaptopodin
chr16_+_57126428 0.12 ENST00000290776.8
CPNE2
copine II
chr10_+_99079008 0.12 ENST00000371021.3
FRAT1
frequently rearranged in advanced T-cell lymphomas
chr9_-_140009130 0.12 ENST00000497375.1
ENST00000371579.2
DPP7
dipeptidyl-peptidase 7
chr16_+_3014269 0.12 ENST00000575885.1
ENST00000571007.1
ENST00000319500.6
KREMEN2
kringle containing transmembrane protein 2
chr17_+_46985823 0.12 ENST00000508468.2
UBE2Z
ubiquitin-conjugating enzyme E2Z
chr20_+_44462749 0.12 ENST00000372541.1
SNX21
sorting nexin family member 21
chr1_+_45792541 0.12 ENST00000334815.3
HPDL
4-hydroxyphenylpyruvate dioxygenase-like
chr9_-_131534188 0.12 ENST00000414921.1
ZER1
zyg-11 related, cell cycle regulator
chr12_+_6493199 0.12 ENST00000228918.4
LTBR
lymphotoxin beta receptor (TNFR superfamily, member 3)
chr19_-_10679644 0.12 ENST00000393599.2
CDKN2D
cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chr1_+_9299895 0.12 ENST00000602477.1
H6PD
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr22_-_36018569 0.12 ENST00000419229.1
ENST00000406324.1
MB
myoglobin
chr19_+_42724423 0.12 ENST00000301215.3
ENST00000597945.1
ZNF526
zinc finger protein 526
chr18_+_3450161 0.12 ENST00000551402.1
ENST00000577543.1
TGIF1
TGFB-induced factor homeobox 1
chr1_-_246670614 0.12 ENST00000403792.3
SMYD3
SET and MYND domain containing 3
chr17_+_7761013 0.12 ENST00000571846.1
CYB5D1
cytochrome b5 domain containing 1
chr1_-_167905225 0.11 ENST00000367846.4
MPC2
mitochondrial pyruvate carrier 2
chr11_-_62380199 0.11 ENST00000419857.1
ENST00000394773.2
EML3
echinoderm microtubule associated protein like 3
chrX_+_152240819 0.11 ENST00000421798.3
ENST00000535416.1
PNMA6C
PNMA6A
paraneoplastic Ma antigen family member 6C
paraneoplastic Ma antigen family member 6A
chr19_+_39833036 0.11 ENST00000602243.1
ENST00000598913.1
ENST00000314471.6
SAMD4B
sterile alpha motif domain containing 4B
chr19_-_49149553 0.11 ENST00000084798.4
CA11
carbonic anhydrase XI
chr16_+_2285817 0.11 ENST00000564065.1
DNASE1L2
deoxyribonuclease I-like 2
chr10_-_35930219 0.11 ENST00000374694.1
FZD8
frizzled family receptor 8
chr14_+_65170820 0.11 ENST00000555982.1
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr14_+_24422795 0.11 ENST00000313250.5
ENST00000558263.1
ENST00000543741.2
ENST00000421831.1
ENST00000397073.2
ENST00000308178.8
ENST00000382761.3
ENST00000397075.3
ENST00000397074.3
ENST00000559632.1
ENST00000558581.1
DHRS4
dehydrogenase/reductase (SDR family) member 4
chr19_-_19739321 0.11 ENST00000588461.1
LPAR2
lysophosphatidic acid receptor 2
chr20_-_49639612 0.11 ENST00000396017.3
ENST00000433903.1
KCNG1
potassium voltage-gated channel, subfamily G, member 1
chr12_-_122238913 0.11 ENST00000537157.1
AC084018.1
AC084018.1
chr15_+_90319557 0.11 ENST00000341735.3
MESP2
mesoderm posterior 2 homolog (mouse)
chr22_-_27620603 0.11 ENST00000418271.1
ENST00000444114.1
RP5-1172A22.1
RP5-1172A22.1
chr6_-_33385854 0.11 ENST00000488478.1
CUTA
cutA divalent cation tolerance homolog (E. coli)
chr17_-_2304365 0.11 ENST00000575394.1
ENST00000174618.4
MNT
MAX network transcriptional repressor
chr8_+_22462145 0.11 ENST00000308511.4
ENST00000523801.1
ENST00000521301.1
CCAR2
cell cycle and apoptosis regulator 2
chr16_-_75285380 0.11 ENST00000393420.6
ENST00000162330.5
BCAR1
breast cancer anti-estrogen resistance 1
chr11_+_47279155 0.11 ENST00000444396.1
ENST00000457932.1
ENST00000412937.1
NR1H3
nuclear receptor subfamily 1, group H, member 3
chr11_-_62379994 0.10 ENST00000278845.4
ENST00000529309.1
EML3
echinoderm microtubule associated protein like 3
chr15_+_75335604 0.10 ENST00000563393.1
PPCDC
phosphopantothenoylcysteine decarboxylase
chr22_+_30115986 0.10 ENST00000216144.3
CABP7
calcium binding protein 7
chr22_-_20255212 0.10 ENST00000416372.1
RTN4R
reticulon 4 receptor
chr17_-_79869340 0.10 ENST00000538936.2
PCYT2
phosphate cytidylyltransferase 2, ethanolamine
chr19_+_42387228 0.10 ENST00000354532.3
ENST00000599846.1
ENST00000347545.4
ARHGEF1
Rho guanine nucleotide exchange factor (GEF) 1
chr3_+_44903361 0.10 ENST00000302392.4
TMEM42
transmembrane protein 42
chr17_+_48638371 0.10 ENST00000360761.4
ENST00000352832.5
ENST00000354983.4
CACNA1G
calcium channel, voltage-dependent, T type, alpha 1G subunit
chr9_+_35605274 0.10 ENST00000336395.5
TESK1
testis-specific kinase 1
chr17_-_33446820 0.10 ENST00000592577.1
ENST00000590016.1
ENST00000345365.6
ENST00000360276.3
ENST00000357906.3
RAD51D
RAD51 paralog D
chr13_-_99852916 0.10 ENST00000426037.2
ENST00000445737.2
UBAC2-AS1
UBAC2 antisense RNA 1
chr19_+_38397839 0.10 ENST00000222345.6
SIPA1L3
signal-induced proliferation-associated 1 like 3
chr2_+_26915584 0.10 ENST00000302909.3
KCNK3
potassium channel, subfamily K, member 3
chr6_-_30654977 0.10 ENST00000399199.3
PPP1R18
protein phosphatase 1, regulatory subunit 18
chr16_-_66586365 0.10 ENST00000562484.2
TK2
thymidine kinase 2, mitochondrial
chr1_+_160370344 0.10 ENST00000368061.2
VANGL2
VANGL planar cell polarity protein 2
chr22_-_46933067 0.10 ENST00000262738.3
ENST00000395964.1
CELSR1
cadherin, EGF LAG seven-pass G-type receptor 1
chr19_-_19774473 0.10 ENST00000357324.6
ATP13A1
ATPase type 13A1
chr12_-_58131931 0.10 ENST00000547588.1
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr8_-_145047688 0.10 ENST00000356346.3
PLEC
plectin
chr11_+_64001962 0.10 ENST00000309422.2
VEGFB
vascular endothelial growth factor B
chr8_+_22844913 0.10 ENST00000519685.1
RHOBTB2
Rho-related BTB domain containing 2
chr16_-_31085514 0.10 ENST00000300849.4
ZNF668
zinc finger protein 668
chr14_+_24458021 0.10 ENST00000397071.1
ENST00000559411.1
ENST00000335125.6
DHRS4L2
dehydrogenase/reductase (SDR family) member 4 like 2
chr3_-_48470838 0.10 ENST00000358459.4
ENST00000358536.4
PLXNB1
plexin B1
chr5_-_176730676 0.09 ENST00000393611.2
ENST00000303251.6
ENST00000303270.6
RAB24
RAB24, member RAS oncogene family
chr8_+_22462532 0.09 ENST00000389279.3
CCAR2
cell cycle and apoptosis regulator 2
chr20_+_2673383 0.09 ENST00000380648.4
ENST00000342725.5
EBF4
early B-cell factor 4
chr3_-_49170522 0.09 ENST00000418109.1
LAMB2
laminin, beta 2 (laminin S)
chr16_-_1401799 0.09 ENST00000007390.2
TSR3
TSR3, 20S rRNA accumulation, homolog (S. cerevisiae)
chr20_-_44516256 0.09 ENST00000372519.3
SPATA25
spermatogenesis associated 25
chr16_+_57126482 0.09 ENST00000537605.1
ENST00000535318.2
CPNE2
copine II
chr16_-_28503080 0.09 ENST00000565316.1
ENST00000565778.1
ENST00000357857.9
ENST00000568558.1
ENST00000357806.7
CLN3
ceroid-lipofuscinosis, neuronal 3
chr17_-_43502987 0.09 ENST00000376922.2
ARHGAP27
Rho GTPase activating protein 27
chr11_-_417388 0.09 ENST00000332725.3
SIGIRR
single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
chr17_+_46985731 0.09 ENST00000360943.5
UBE2Z
ubiquitin-conjugating enzyme E2Z
chr16_-_71323617 0.09 ENST00000563876.1
CMTR2
cap methyltransferase 2
chr22_+_42229100 0.09 ENST00000361204.4
SREBF2
sterol regulatory element binding transcription factor 2
chr11_-_6502534 0.09 ENST00000254584.2
ENST00000525235.1
ENST00000445086.2
ARFIP2
ADP-ribosylation factor interacting protein 2
chr14_+_92980111 0.09 ENST00000216487.7
ENST00000557762.1
RIN3
Ras and Rab interactor 3
chr1_+_154377669 0.09 ENST00000368485.3
ENST00000344086.4
IL6R
interleukin 6 receptor
chr15_+_29211570 0.08 ENST00000558804.1
APBA2
amyloid beta (A4) precursor protein-binding, family A, member 2
chr22_+_31742875 0.08 ENST00000504184.2
AC005003.1
CDNA FLJ20464 fis, clone KAT06158; HCG1777549; Uncharacterized protein
chr6_+_143381594 0.08 ENST00000367601.4
AIG1
androgen-induced 1
chr4_+_8271471 0.08 ENST00000307358.2
ENST00000382512.3
HTRA3
HtrA serine peptidase 3

Network of associatons between targets according to the STRING database.

First level regulatory network of TFAP2B

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0052151 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.1 0.8 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.1 0.3 GO:0061536 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.1 0.7 GO:0070235 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 0.2 GO:0060490 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.1 0.2 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.1 0.2 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
0.0 0.3 GO:0019087 transformation of host cell by virus(GO:0019087) renal water absorption(GO:0070295)
0.0 0.1 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.3 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.0 0.1 GO:0061145 bronchus cartilage development(GO:0060532) lung smooth muscle development(GO:0061145)
0.0 0.2 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.0 0.3 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.2 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.0 0.1 GO:0036451 cap mRNA methylation(GO:0036451)
0.0 0.1 GO:0072312 metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
0.0 0.2 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.3 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
0.0 0.1 GO:0002384 hepatic immune response(GO:0002384)
0.0 0.1 GO:0006850 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.0 0.2 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.0 0.1 GO:0003335 corneocyte development(GO:0003335)
0.0 0.1 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.0 0.1 GO:0015793 glycerol transport(GO:0015793)
0.0 0.2 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.1 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.0 0.1 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0 0.1 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
0.0 0.1 GO:0061760 antifungal humoral response(GO:0019732) antifungal innate immune response(GO:0061760)
0.0 0.1 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.0 0.1 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.0 0.1 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.0 0.1 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.0 0.1 GO:2001178 mediator complex assembly(GO:0036034) regulation of mediator complex assembly(GO:2001176) positive regulation of mediator complex assembly(GO:2001178)
0.0 0.9 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.1 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.0 0.0 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0 0.1 GO:0046092 deoxycytidine metabolic process(GO:0046092)
0.0 0.2 GO:0045542 positive regulation of cholesterol biosynthetic process(GO:0045542)
0.0 0.2 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.0 0.1 GO:1990785 response to water-immersion restraint stress(GO:1990785)
0.0 0.1 GO:0009956 radial pattern formation(GO:0009956)
0.0 0.1 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.0 0.2 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.0 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.0 0.1 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.0 0.1 GO:0061143 alveolar primary septum development(GO:0061143)
0.0 0.3 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.1 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
0.0 0.1 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.3 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.0 0.7 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.4 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.6 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.1 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.1 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.0 0.2 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.1 GO:0098886 modification of dendritic spine(GO:0098886)
0.0 0.2 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.2 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 0.1 GO:1901162 primary amino compound biosynthetic process(GO:1901162)
0.0 0.1 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.1 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.0 0.2 GO:0015886 heme transport(GO:0015886)
0.0 0.0 GO:2000742 anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.0 0.3 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.1 GO:1901382 chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
0.0 0.1 GO:0015798 myo-inositol transport(GO:0015798)
0.0 0.1 GO:1903906 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.0 0.1 GO:0048102 autophagic cell death(GO:0048102)
0.0 0.3 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.0 0.0 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.2 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.1 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.1 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.0 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0044609 DBIRD complex(GO:0044609)
0.1 0.2 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 0.1 GO:0005608 laminin-3 complex(GO:0005608)
0.0 0.2 GO:0044194 cytolytic granule(GO:0044194)
0.0 0.1 GO:0097444 spine apparatus(GO:0097444)
0.0 0.4 GO:0008274 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0 0.1 GO:0070110 ciliary neurotrophic factor receptor complex(GO:0070110)
0.0 0.2 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.1 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.0 0.1 GO:0060187 cell pole(GO:0060187)
0.0 0.1 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.1 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.2 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.8 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.2 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.1 GO:0001739 sex chromatin(GO:0001739)
0.0 0.2 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.3 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.4 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.3 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.2 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 0.4 GO:0004324 ferredoxin-NADP+ reductase activity(GO:0004324) NADPH-adrenodoxin reductase activity(GO:0015039) oxidoreductase activity, acting on iron-sulfur proteins as donors(GO:0016730) oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor(GO:0016731)
0.1 0.3 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.1 0.3 GO:0033906 protein tyrosine kinase inhibitor activity(GO:0030292) hyaluronoglucuronidase activity(GO:0033906)
0.0 0.3 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.0 0.4 GO:0032810 sterol response element binding(GO:0032810)
0.0 0.1 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.0 0.2 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.0 0.1 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.0 0.1 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.0 0.1 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.0 0.1 GO:0038131 neuregulin receptor activity(GO:0038131)
0.0 0.4 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.2 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.2 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 0.6 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.1 GO:0010736 serum response element binding(GO:0010736)
0.0 0.1 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.0 0.1 GO:0008478 pyridoxal kinase activity(GO:0008478)
0.0 0.1 GO:0090541 MIT domain binding(GO:0090541)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.5 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.0 0.1 GO:0004137 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.0 0.1 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.0 0.2 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.1 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.0 0.1 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.0 0.1 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.0 0.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.3 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.2 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.1 GO:0016213 linoleoyl-CoA desaturase activity(GO:0016213)
0.0 0.4 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.3 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.1 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.0 GO:0030617 transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity(GO:0030617)
0.0 0.3 GO:0033613 activating transcription factor binding(GO:0033613)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.1 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.0 0.4 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.3 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.2 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.1 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins